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name Structure Reference Source Properties Activities Metabolism

Giracodazole; (2'S,3'S)-form 

AlkaPlorer ID: AK299232

Synonym: None

IUPAC Name: 3-amino-1-(2-amino-1H-imidazol-5-yl)-2-chloropropan-1-ol

Structure

SMILES: N=C1NC=C(C(O)C(Cl)CN)N1

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InChI: InChI=1S/C6H11ClN4O/c7-3(1-8)5(12)4-2-10-6(9)11-4/h2-3,5,12H,1,8H2,(H3,9,10,11)

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InChIKey: YILCGOCHVFQMTC-UHFFFAOYSA-N

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Source

Species Genus Family Order Class Phylum Kingdom Domain
Cymbastela cantharella Cymbastela Axinellidae Axinellida Demospongiae Porifera Metazoa Eukaryota

Properties Information

Molecule Weight: 190.634

TPSA？: 101.68

MolLogP？: -0.5782300000000002

Number of H-Donors: 5

Number of H-Acceptors: 3

RingCount: 1

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Homo sapiens A498 GI50 147.23 nM None
Homo sapiens A549 GI50 135.83 nM None
Homo sapiens CAKI-1 GI50 268.53 nM None
Homo sapiens CCRF-CEM GI50 1581.25 nM None
Homo sapiens COLO 205 GI50 306.2 nM None
Homo sapiens DLD-1 GI50 1836.54 nM None
Homo sapiens DMS-114 GI50 1538.15 nM None
Homo sapiens DMS-273 GI50 2046.44 nM None
Homo sapiens EKVX GI50 502.34 nM None
Homo sapiens HCC 2998 GI50 625.17 nM None
Homo sapiens HCT-116 GI50 391.74 nM None
Homo sapiens HCT-15 GI50 3475.36 nM None
Homo sapiens HL-60 GI50 3459.39 nM None
Homo sapiens HOP-18 GI50 275.42 nM None
Homo sapiens HOP-62 GI50 370.68 nM None
Homo sapiens HOP-92 GI50 5457.58 nM None
Homo sapiens HT-29 GI50 453.94 nM None
Homo sapiens IGROV-1 GI50 244.91 nM None
Homo sapiens K562 GI50 2382.32 nM None
Homo sapiens KM12 GI50 117.22 nM None
Homo sapiens KM-20L2 GI50 595.66 nM None
Homo sapiens LOX IMVI GI50 1235.95 nM None
Homo sapiens M19-MEL GI50 2523.48 nM None
Homo sapiens Malme-3M GI50 1432.19 nM None
Homo sapiens MCF7 GI50 2766.94 nM None
Homo sapiens MOLT-4 GI50 529.66 nM None
Homo sapiens NCI/ADR-RES GI50 595.66 nM None
Homo sapiens NCI-H226 GI50 2152.78 nM None
Homo sapiens NCI-H23 GI50 1492.79 nM None
Homo sapiens NCI-H322M GI50 1458.81 nM None
Homo sapiens NCI-H460 GI50 2142.89 nM None
Homo sapiens NCI-H522 GI50 1927.52 nM None
Homo sapiens OVCAR-3 GI50 2032.36 nM None
Homo sapiens OVCAR-4 GI50 668.34 nM None
Homo sapiens OVCAR-5 GI50 2009.09 nM None
Homo sapiens OVCAR-8 GI50 545.76 nM None
Homo sapiens RPMI-8226 GI50 236.59 nM None
Homo sapiens RXF 393 GI50 1193.99 nM None
Homo sapiens SF-268 GI50 1380.38 nM None
Homo sapiens SF-295 GI50 4305.27 nM None
Homo sapiens SF-539 GI50 473.15 nM None
Homo sapiens SK-MEL-2 GI50 3564.51 nM None
Homo sapiens SK-MEL-28 GI50 3605.79 nM None
Homo sapiens SK-MEL-5 GI50 7328.25 nM None
Homo sapiens SK-OV-3 GI50 533.33 nM None
Homo sapiens SN12C GI50 2118.36 nM None
Homo sapiens SN12K1 GI50 506.99 nM None
Homo sapiens SNB-19 GI50 1156.11 nM None
Homo sapiens SNB-75 GI50 1840.77 nM None
Homo sapiens SNB-78 GI50 9794.9 nM None
Homo sapiens SW-620 GI50 369.83 nM None
Homo sapiens U-251 GI50 1032.76 nM None
Homo sapiens UACC-257 GI50 3047.89 nM None
Homo sapiens UACC-62 GI50 3013.01 nM None
Homo sapiens UO-31 GI50 822.24 nM None
Homo sapiens XF498 GI50 2449.06 nM None
Mus musculus P388 GI50 35.32 nM None
Mus musculus P388/ADR GI50 231.74 nM None

Metabolism Information