2-Hexadecenoic acid; (E)-form, Piperidide
AlkaPlorer ID: AK300279
Synonym: 2-Hexadecenoic acid piperidide, Piperlongimine B
IUPAC Name: (E)-1-piperidin-1-ylhexadec-2-en-1-one
Structure
SMILES: CCCCCCCCCCCCC/C=C/C(=O)N1CCCCC1
InChI: InChI=1S/C21H39NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-21(23)22-19-16-14-17-20-22/h15,18H,2-14,16-17,19-20H2,1H3/b18-15+
InChIKey: VXMNUDFIHMERAX-OBGWFSINSA-N
Reference
Two new amides with cytotoxic activity from the fruits of<i>Piper longum</i>
PubChem CID: 53253850
CAS: 147030-05-5
LOTUS: LTS0239037
SuperNatural Ⅲ: SN0402738-01
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Piper longum | Piper | Piperaceae | Piperales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 321.5490000000001
TPSA？: 20.31
MolLogP？: 6.256200000000007
Number of H-Donors: 0
Number of H-Acceptors: 1
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Electrophorus electricus | Acetylcholinesterase | Inhibition | 51.86 | % | 10.1016/j.ejmech.2017.07.081 |
| Electrophorus electricus | Acetylcholinesterase | Ki | 7450.0 | nM | 10.1016/j.ejmech.2017.07.081 |
| Electrophorus electricus | Acetylcholinesterase | Ki | 50000.0 | nM | 10.1016/j.ejmech.2017.07.081 |
| Equus caballus | Cholinesterase | Inhibition | 17.76 | % | 10.1016/j.ejmech.2017.07.081 |
| Homo sapiens | A253 cell line | Survival | 57.0 | % | 10.1016/j.ejmech.2017.07.081 |
| Homo sapiens | FaDu | Survival | 90.0 | % | 10.1016/j.ejmech.2017.07.081 |
| Homo sapiens | HT-29 | Survival | 47.0 | % | 10.1016/j.ejmech.2017.07.081 |
| Homo sapiens | MCF7 | Survival | 40.0 | % | 10.1016/j.ejmech.2017.07.081 |
| Homo sapiens | SW-1736 | Survival | 77.0 | % | 10.1016/j.ejmech.2017.07.081 |
| Mus musculus | NIH3T3 | Survival | 80.0 | % | 10.1016/j.ejmech.2017.07.081 |