Histidine; (±)-form, Nα-Ac
AlkaPlorer ID: AK300497
Synonym: None
IUPAC Name: 2-acetamido-3-(1H-imidazol-5-yl)propanoic acid
Structure
SMILES: CC(=O)NC(CC1=CNC=N1)C(=O)O
InChI: InChI=1S/C8H11N3O3/c1-5(12)11-7(8(13)14)2-6-3-9-4-10-6/h3-4,7H,2H2,1H3,(H,9,10)(H,11,12)(H,13,14)
InChIKey: KBOJOGQFRVVWBH-UHFFFAOYSA-N
Source
Properties Information
Molecule Weight: 197.194
TPSA？: 95.08
MolLogP？: -0.4585000000000006
Number of H-Donors: 3
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Escherichia coli | Escherichia coli | AC50 | 29246.0 | nM | None |
| Escherichia coli K-12 | Beta-lactamase AmpC | Potency | 44668.4 | nM | None |
| Homo sapiens | DNA polymerase iota | Potency | 5011.9 | nM | None |
| Homo sapiens | Guanine nucleotide-binding protein G(s), subunit alpha | Potency | 11220.2 | nM | None |
| Homo sapiens | Lysosomal alpha-glucosidase | Potency | 50118.7 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 41094.8 | nM | None |
| Influenza A virus | Nonstructural protein 1 | Potency | 11220.2 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 73.8 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 369.6 | nM | None |