3-Hydroxy-11-norcytisine
AlkaPlorer ID: AK301660
Synonym: 2,3,4,5-Tetrahydro-8-hydroxy-1,4-methanopyrido[1,2-a][1,4]diazepin-7(1H)-one
IUPAC Name: 5-hydroxy-7,11-diazatricyclo[7.2.1.02,7]dodeca-2,4-dien-6-one
Structure
SMILES: O=C1C(O)=CC=C2C3CC(CN3)CN21
InChI: InChI=1S/C10H12N2O2/c13-9-2-1-8-7-3-6(4-11-7)5-12(8)10(9)14/h1-2,6-7,11,13H,3-5H2
InChIKey: AFTDVOKQJZAVLI-UHFFFAOYSA-N
Reference
Hydroxynorcytisine, a quinolizidone alkaloid from Laburnum anagyroides
PubChem CID: 74426088
CAS: 121063-35-2
LOTUS: LTS0115782
COCONUT: CNP0235091.2
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Laburnum anagyroides | Laburnum | Fabaceae | Fabales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 192.218
TPSA？: 54.26
MolLogP？: 0.2180999999999998
Number of H-Donors: 2
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Rattus norvegicus | Neuronal acetylcholine receptor; alpha4/beta2 | Ki | 14000.0 | nM | 10.1016/j.bmc.2020.115820 |
| Rattus norvegicus | Neuronal acetylcholine receptor protein alpha-7 subunit | Ki | 260000.0 | nM | 10.1016/j.bmc.2020.115820 |