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2-Iminopiperidine

AlkaPlorer ID: AK302385

Synonym: 2-Piperidinimine

IUPAC Name: 2,3,4,5-tetrahydropyridin-6-amine

Structure

SMILES: N=C1CCCCN1

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InChI: InChI=1S/C5H10N2/c6-5-3-1-2-4-7-5/h1-4H2,(H2,6,7)

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InChIKey: DHGUMNJVFYRSIG-UHFFFAOYSA-N

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Reference

PubChem CID: 85237

CAS: 22780-54-7

Properties Information

Molecule Weight: 98.149

TPSA？: 35.88

MolLogP？: 0.7371699999999999

Number of H-Donors: 2

Number of H-Acceptors: 1

RingCount: 1

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Homo sapiens Cytochrome P450 1A2 AC50 nan None None
Homo sapiens Cytochrome P450 2C19 AC50 nan None None
Homo sapiens Cytochrome P450 2C9 AC50 nan None None
Homo sapiens Cytochrome P450 2D6 AC50 nan None None
Homo sapiens Cytochrome P450 3A4 AC50 nan None None
Homo sapiens Endoplasmic reticulum-associated amyloid beta-peptide-binding protein Potency 39810.7 nM None
Homo sapiens Menin/Histone-lysine N-methyltransferase MLL Potency 39810.7 nM None
Homo sapiens Nitric-oxide synthase, brain IC50 240.0 nM 10.1016/j.bmcl.2005.02.067
Homo sapiens Nitric-oxide synthase, brain IC50 1100.0 nM 10.1021/jm950766n
Homo sapiens Nitric-oxide synthase, brain IC50 1100.0 nM 10.1021/jm9705059
Homo sapiens Nitric-oxide synthase, endothelial IC50 630.0 nM 10.1016/j.bmcl.2005.02.067
Homo sapiens Nitric-oxide synthase, endothelial IC50 4700.0 nM 10.1021/jm950766n
Homo sapiens Nitric-oxide synthase, endothelial IC50 4700.0 nM 10.1021/jm9705059
Homo sapiens Nitric oxide synthase, inducible IC50 300.0 nM 10.1016/j.bmcl.2005.02.067
Homo sapiens Nitric oxide synthase, inducible IC50 1000.0 nM 10.1021/jm950766n
Homo sapiens Nitric oxide synthase, inducible IC50 1100.0 nM 10.1021/jm9705059
Homo sapiens Nitric oxide synthase (inducible and endothelial) Selectivity 2.1 None 10.1016/j.bmcl.2005.02.067
Homo sapiens Nitric oxide synthase (inducible and endothelial) Selectivity 4.0 None 10.1021/jm9705059
Homo sapiens Nitric oxide sythases; iNOS & nNOS Selectivity 1.0 None 10.1021/jm9705059
Homo sapiens Nitric oxide sythases; iNOS & nNOS Selectivity 8.0 None 10.1016/j.bmcl.2005.02.067
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 2660.9 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 3758.6 nM None
Rattus norvegicus Rattus norvegicus Inhibition 62.0 % 10.1021/jm9705059
None Unchecked Selectivity 1.1 None 10.1021/jm950766n
None Unchecked Selectivity 4.7 None 10.1021/jm950766n

Metabolism Information