1H-Indole-2,3-diol; (ξ)-Oxindole-form
AlkaPlorer ID: AK302499
Synonym: None
IUPAC Name: 3-hydroxy-1,3-dihydroindol-2-one
Structure
SMILES: O=C1NC2=CC=CC=C2C1O
InChI: InChI=1S/C8H7NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4,7,10H,(H,9,11)
InChIKey: SGZFJWQQBHYNNF-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Sphyraena japonica | Sphyraena | Sphyraenidae | None | Actinopteri | Chordata | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 149.14899999999997
TPSA？: 49.33
MolLogP？: 0.6720999999999999
Number of H-Donors: 2
Number of H-Acceptors: 2
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Acinetobacter baumannii | Acinetobacter baumannii | Inhibition | 0.09 | % | 10.6019/CHEMBL4513160 |
| Homo sapiens | D-amino-acid oxidase | IC50 | 100000.0 | nM | 10.1021/ml300212a |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | Inhibition | -3.58 | % | 10.6019/CHEMBL4513160 |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | Inhibition | 18.01 | % | 10.6019/CHEMBL4513160 |
| None | Unchecked | Percent Effect | -7.262 | % | 10.6019/CHEMBL3988442 |
| None | Unchecked | Percent Effect | 0.1265 | % | 10.6019/CHEMBL3988442 |
| None | Unchecked | Percent Effect | 4.302 | % | 10.6019/CHEMBL3988442 |