Myxopyronines; Myxopyronine B
AlkaPlorer ID: AK307250
Synonym: None
IUPAC Name: methyl N-[(Z)-5-[5-[(2E,4E)-2,5-dimethylnona-2,4-dienoyl]-4-hydroxy-6-oxopyran-2-yl]hex-1-enyl]carbamate
Structure
SMILES: CCCC/C(C)=C/C=C(\C)C(=O)C1=C(O)C=C(C(C)CC/C=C\NC(=O)OC)OC1=O
InChI: InChI=1S/C24H33NO6/c1-6-7-10-16(2)12-13-18(4)22(27)21-19(26)15-20(31-23(21)28)17(3)11-8-9-14-25-24(29)30-5/h9,12-15,17,26H,6-8,10-11H2,1-5H3,(H,25,29)/b14-9-,16-12+,18-13+
InChIKey: SPQDIDVJAZFBRL-YNYJKMOFSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Myxococcus fulvus | Myxococcus | Myxococcaceae | Myxococcales | Myxococcia | Myxococcota | None | Bacteria |
Properties Information
Molecule Weight: 431.5290000000002
TPSA？: 105.84
MolLogP？: 5.3643000000000045
Number of H-Donors: 2
Number of H-Acceptors: 6
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Escherichia coli | Escherichia coli | MIC | 4.0 | ug.mL-1 | 10.1016/j.bmcl.2004.08.045 |
| Escherichia coli | Escherichia coli | MIC | 64.0 | ug.mL-1 | 10.1016/j.bmcl.2004.08.045 |
| Escherichia coli K-12 | DNA-directed RNA polymerase beta chain | IC50 | 1260.0 | nM | 10.1016/j.bmcl.2004.08.045 |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 4.0 | ug.mL-1 | 10.1016/j.bmcl.2004.08.045 |