Narcotinediol
AlkaPlorer ID: AK307432
Synonym: None
IUPAC Name: [2-(hydroxymethyl)-3,4-dimethoxyphenyl]-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methanol
Structure
SMILES: COC1=CC=C(C(O)C2C3=C(OC)C4=C(C=C3CCN2C)OCO4)C(CO)=C1OC
InChI: InChI=1S/C22H27NO7/c1-23-8-7-12-9-16-21(30-11-29-16)22(28-4)17(12)18(23)19(25)13-5-6-15(26-2)20(27-3)14(13)10-24/h5-6,9,18-19,24-25H,7-8,10-11H2,1-4H3
InChIKey: BHLLOBXLOWXZDQ-UHFFFAOYSA-N
Reference
(-)-Papaveroxidine, A Modified Phthalideisoquinoline Alkaloid from Papaver Pseudo-orientale
PubChem CID: 98447
CAS: 23942-99-6
LOTUS: LTS0021061
COCONUT: CNP0258529.1
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Papaver pseudo-orientale | Papaver | Papaveraceae | Ranunculales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 417.4580000000002
TPSA？: 89.85000000000001
MolLogP？: 2.196
Number of H-Donors: 2
Number of H-Acceptors: 8
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 8000.0 | nM | 10.1016/s0960-894x(01)00811-3 |