2-Piperidinecarboxylic acid; (±)-form
AlkaPlorer ID: AK310518
Synonym: None
IUPAC Name: piperidine-2-carboxylate
Structure
SMILES: O=C([O-])C1CCCCN1
InChI: InChI=1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)/p-1
InChIKey: HXEACLLIILLPRG-UHFFFAOYSA-M
Reference
Amino Acids and gamma-Glutamyl Derivatives in Seeds of Lunaria annua L. Part III.
PubChem CID: 5461049
CAS: 535-75-1
LOTUS: LTS0189894
NPASS: NPC64250
COCONUT: CNP0148927.2
Source
Properties Information
Molecule Weight: 128.151
TPSA？: 52.16
MolLogP？: -1.1216000000000004
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Cyclooxygenase-2 | Inhibition | 30.0 | % | 10.1021/np020023m |
| Homo sapiens | Peroxisomal sarcosine oxidase | Km | 3700000.0 | nM | 10.1021/jm960331f |
| Homo sapiens | Peroxisomal sarcosine oxidase | Vmax | 2.1 | uM min-1mg-1 | 10.1021/jm960331f |
| Homo sapiens | Zinc finger protein GLI1 | Inhibition | nan | % | 10.1016/j.bmcl.2016.08.008 |
| Rattus norvegicus | Carnitine/acylcarnitine translocase | Experimental DPM | 4275.0 | None | 10.1021/jm00155a045 |
| Saccharomyces cerevisiae | General amino-acid permease GAP1 | Inhibition | 15.0 | % | 10.1038/nchembio.132 |
| Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) | Dihydrodipicolinate synthase | Inhibition | 0.0 | % | 10.1016/0960-894X(94)85023-2 |
| None | Unchecked | Anticonvulsant activity | nan | None | 10.1016/s0960-894x(03)00535-3 |