Molecule

Streptomycin

AlkaPlorer ID: AK314493

Synonym: N-Methyl-L-glucosamidinostreptosidostreptidine, Streptomisin, Agrept, Agrimycin, Merstep, NSC 14083, Many other names

IUPAC Name: 2-[3-(diaminomethylideneamino)-4-[3-[4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine

Structure

SMILES: CNC1C(OC2C(OC3C(O)C(O)C(NC(=N)N)C(O)C3NC(=N)N)OC(C)C2(O)C=O)OC(CO)C(O)C1O

InChI: InChI=1S/C21H39N7O12/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28)

InChIKey: UCSJYZPVAKXKNQ-UHFFFAOYSA-N

Reference

Streptomycin-Induced Expression in Bacillus subtilis of YtnP, a Lactonase-Homologous Protein That Inhibits Development and Streptomycin Production in Streptomyces griseus

PubChem CID: 5297

CAS: 57-92-1

LOTUS: LTS0245554

COCONUT: CNP0149907.8

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Streptomyces galbus	Streptomyces	Streptomycetaceae	Kitasatosporales	Actinomycetes	Actinomycetota	None	Bacteria
None	Streptomyces	Streptomycetaceae	Kitasatosporales	Actinomycetes	Actinomycetota	None	Bacteria
Streptomyces griseus	Streptomyces	Streptomycetaceae	Kitasatosporales	Actinomycetes	Actinomycetota	None	Bacteria
Streptomyces bikiniensis	Streptomyces	Streptomycetaceae	Kitasatosporales	Actinomycetes	Actinomycetota	None	Bacteria
Streptomyces olivaceus	Streptomyces	Streptomycetaceae	Kitasatosporales	Actinomycetes	Actinomycetota	None	Bacteria
Streptomyces erythrochromogenes	Streptomyces	Streptomycetaceae	Kitasatosporales	Actinomycetes	Actinomycetota	None	Bacteria

Properties Information

Molecule Weight: 581.5800000000004

TPSA？: 331.43000000000006

MolLogP？: -7.741760000000005

Number of H-Donors: 14

Number of H-Acceptors: 15

RingCount: 3

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Homo sapiens	Cytochrome P450 1A2	AC50	nan	None	None
Homo sapiens	Cytochrome P450 2C19	AC50	nan	None	None
Homo sapiens	Cytochrome P450 2C9	AC50	nan	None	None
Homo sapiens	Cytochrome P450 2D6	AC50	nan	None	None
Homo sapiens	Cytochrome P450 3A4	AC50	nan	None	None
Homo sapiens	Ferrochelatase, mitochondrial	Inhibition	nan	%	10.6019/CHEMBL3987221
Homo sapiens	Porphobilinogen deaminase	Inhibition	nan	%	10.6019/CHEMBL3987221
Homo sapiens	Prelamin-A/C	Potency	8.9	nM	None
Homo sapiens	Thyroid hormone receptor beta-1	Potency	3.5	nM	None
Naegleria gruberi	Naegleria gruberi	Inhibition	0.0	%	10.6019/CHEMBL4513101
None	NON-PROTEIN TARGET	Potency	0.2	nM	None
None	NON-PROTEIN TARGET	Potency	7.6	nM	None
None	NON-PROTEIN TARGET	Potency	9.5	nM	None
None	NON-PROTEIN TARGET	Potency	211.2	nM	None
None	NON-PROTEIN TARGET	Potency	13324.4	nM	None
None	NON-PROTEIN TARGET	Potency	21117.7	nM	None