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Tricholomic acid

AlkaPlorer ID: AK316328

Synonym: α-Amino-3-oxo-5-isoxazolidineacetic acid, 2-(3-Oxo-5-isoxazolidinyl)glycine

IUPAC Name: 2-amino-2-(3-oxo-1,2-oxazolidin-5-yl)acetic acid

Structure

SMILES: NC(C(=O)O)C1CC(O)=NO1

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InChI: InChI=1S/C5H8N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h2,4H,1,6H2,(H,7,8)(H,9,10)

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InChIKey: NTHMUJMQOXQYBR-UHFFFAOYSA-N

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Reference

PubChem CID: 59951973

CAS: 2644-49-7

COCONUT: CNP0326054.3

Source

Species Genus Family Order Class Phylum Kingdom Domain
Tricholoma muscarium Tricholoma Tricholomataceae Agaricales Agaricomycetes Basidiomycota Fungi Eukaryota

Properties Information

Molecule Weight: 160.129

TPSA？: 105.14

MolLogP？: -0.9412999999999996

Number of H-Donors: 3

Number of H-Acceptors: 4

RingCount: 1

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Rattus norvegicus Glutamate NMDA receptor IC50 1500.0 nM 10.1021/jm701394a
Rattus norvegicus Glutamate NMDA receptor IC50 1513.56 nM 10.1021/jm701394a
Rattus norvegicus Glutamate NMDA receptor IC50 72443.6 nM 10.1021/jm701394a
Rattus norvegicus Glutamate NMDA receptor IC50 73000.0 nM 10.1021/jm701394a
Rattus norvegicus Metabotropic glutamate receptor 1 EC50 110000.0 nM 10.1021/jm701394a
Rattus norvegicus Metabotropic glutamate receptor 1 EC50 790000.0 nM 10.1021/jm701394a
Rattus norvegicus Metabotropic glutamate receptor 1 EC50 1258925411794.17 nM 10.1021/jm701394a
Rattus norvegicus Metabotropic glutamate receptor 1 EC50 12589254117941.66 nM 10.1021/jm701394a
Rattus norvegicus Metabotropic glutamate receptor 2 EC50 100000.0 nM 10.1021/jm701394a
Rattus norvegicus Metabotropic glutamate receptor 2 EC50 1000000.0 nM 10.1021/jm701394a
Rattus norvegicus Metabotropic glutamate receptor 4 EC50 1000000.0 nM 10.1021/jm701394a
None Unchecked IC50 724.44 nM 10.1021/jm701394a
None Unchecked IC50 760.0 nM 10.1021/jm701394a
None Unchecked IC50 1100.0 nM 10.1021/jm701394a
None Unchecked IC50 1380.38 nM 10.1021/jm701394a
None Unchecked IC50 6000.0 nM 10.1021/jm701394a
None Unchecked IC50 6025.6 nM 10.1021/jm701394a
None Unchecked IC50 18620.87 nM 10.1021/jm701394a
None Unchecked IC50 19000.0 nM 10.1021/jm701394a

Metabolism Information