Viomycin
AlkaPlorer ID: AK317720
Synonym: Vinactin A, Vinactane, Celiomycin, Viocin, Tuberactinomycin B, Florimycin, Koluopthisin, Antibiotic S 300, Phtiomycin, Vionactane, Vioactane
IUPAC Name: 3,6-diamino-N-[(6Z)-3-(2-amino-4-hydroxy-1,4,5,6-tetrahydropyrimidin-6-yl)-6-[(carbamoylamino)methylidene]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentazacyclohexadec-15-yl]hexanamide
Structure
SMILES: N=C1NC(O)CC(C2NC(=O)/C(=C/NC(N)=O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(NC(=O)CC(N)CCCN)CNC2=O)N1
InChI: InChI=1S/C25H43N13O10/c26-3-1-2-10(27)4-16(41)32-12-6-30-23(47)18(11-5-17(42)37-24(28)36-11)38-20(44)13(7-31-25(29)48)33-21(45)14(8-39)35-22(46)15(9-40)34-19(12)43/h7,10-12,14-15,17-18,39-40,42H,1-6,8-9,26-27H2,(H,30,47)(H,32,41)(H,33,45)(H,34,43)(H,35,46)(H,38,44)(H3,28,36,37)(H3,29,31,48)/b13-7-
InChIKey: GXFAIFRPOKBQRV-QPEQYQDCSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 685.6999999999997
TPSA？: 390.35999999999984
MolLogP？: -8.673130000000013
Number of H-Donors: 16
Number of H-Acceptors: 13
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Histone-lysine N-methyltransferase MLL | Potency | 14125.4 | nM | None |
| Homo sapiens | Muscleblind-like protein 1 | Potency | 32609.2 | nM | None |
| Homo sapiens | Muscleblind-like protein 1 | Potency | 46061.7 | nM | None |
| Trypanosoma brucei | 6-phospho-1-fructokinase | Potency | 39810.7 | nM | None |