Molecule

Hydrazidomycin B

AlkaPlorer ID: AK318974

Synonym: None

IUPAC Name: N-[(1Z,8Z)-hexadeca-1,8-dienyl]-N'-(2-methoxyacetyl)decanehydrazide

Structure

SMILES: CCCCCCC/C=C\CCCCC/C=C\N(NC(=O)COC)C(=O)CCCCCCCCC

InChI: InChI=1S/C29H54N2O3/c1-4-6-8-10-12-13-14-15-16-17-18-20-22-24-26-31(30-28(32)27-34-3)29(33)25-23-21-19-11-9-7-5-2/h14-15,24,26H,4-13,16-23,25,27H2,1-3H3,(H,30,32)/b15-14-,26-24-

InChIKey: SLWJBIZOZMCRQW-JYWRQANJSA-N

Reference

Hydrazidomycins, cytotoxic alkylhydrazides from Streptomyces atratus

PubChem CID: 53483941

LOTUS: LTS0163049

NPASS: NPC19497

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NPAtlas: NPA016330

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Streptomyces atratus	Streptomyces	Streptomycetaceae	Kitasatosporales	Actinomycetes	Actinomycetota	None	Bacteria

Properties Information

Molecule Weight: 478.7620000000005

TPSA？: 58.64000000000001

MolLogP？: 8.01420000000001

Number of H-Donors: 1

Number of H-Acceptors: 3

RingCount: 0

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Homo sapiens	CAL-27	IC50	12700.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	CWR22R	IC50	15600.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	DU-145	IC50	7220.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	HCT-116	IC50	19400.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	HT-29	IC50	6540.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	LNCaP	IC50	14100.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	MCF7	IC50	11000.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	MDA-MB-231	IC50	5530.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	MKN-45	IC50	11600.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	NCI-H460	IC50	17200.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	PANC-1	IC50	10000.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	RKO	IC50	13800.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	SAOS-2	IC50	18000.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	T-24	IC50	9190.0	nM	10.1016/j.bmcl.2011.07.108
Homo sapiens	TE-671	IC50	18200.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	876.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	1410.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	1540.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	1730.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	5940.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	7070.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	7390.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	10200.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	10800.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	11000.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	12600.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	12700.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	14300.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	14900.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	15100.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	17300.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	17400.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	18200.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	18300.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	18500.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	19100.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	19300.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	20400.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	21200.0	nM	10.1016/j.bmcl.2011.07.108
None	NON-PROTEIN TARGET	IC50	30000.0	nM	10.1016/j.bmcl.2011.07.108