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(2E)-3-phenyl-N-(2-phenylethyl)prop-2-enamide

AlkaPlorer ID: AK319050

Synonym: None

IUPAC Name: (E)-3-phenyl-N-(2-phenylethyl)prop-2-enamide

Structure

SMILES: OC(/C=C/C1=CC=CC=C1)=NCCC1=CC=CC=C1

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InChI: InChI=1S/C17H17NO/c19-17(12-11-15-7-3-1-4-8-15)18-14-13-16-9-5-2-6-10-16/h1-12H,13-14H2,(H,18,19)/b12-11+

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InChIKey: BOSUEWCVNFFBGV-VAWYXSNFSA-N

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Reference

The N-2-phenylethylcinnamamide from Spilanthes ocymifolia

PubChem CID: 795855

CAS: 55030-23-4

LOTUS: LTS0013880

SuperNatural Ⅲ: SN0031311-02

NPASS: NPC203076

data_source: manually

Properties Information

Molecule Weight: 251.329

TPSA？: 32.59

MolLogP？: 3.899000000000002

Number of H-Donors: 1

Number of H-Acceptors: 1

RingCount: 2

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Homo sapiens ATPase family AAA domain-containing protein 5 Potency 20587.8 nM None
Homo sapiens ATP-dependent DNA helicase Q1 Potency 354.8 nM None
Homo sapiens ATP-dependent DNA helicase Q1 Potency 17782.8 nM None
Homo sapiens ATP-dependent DNA helicase Q1 Potency 39810.7 nM None
Homo sapiens Bromodomain adjacent to zinc finger domain protein 2B Potency 79432.8 nM None
Homo sapiens DNA-(apurinic or apyrimidinic site) lyase Potency 7943.3 nM None
Homo sapiens DNA polymerase beta Potency 25118.9 nM None
Homo sapiens DNA polymerase eta Potency 19952.6 nM None
Homo sapiens DNA polymerase eta Potency 67455.5 nM None
Homo sapiens DNA polymerase iota Potency 56234.1 nM None
Homo sapiens DNA polymerase iota Potency 67015.8 nM None
Homo sapiens DNA polymerase kappa Potency 56234.1 nM None
Homo sapiens Geminin Potency 65.1 nM None
Homo sapiens Histone acetyltransferase GCN5 Potency 39810.7 nM None
Homo sapiens Lysine-specific demethylase 4A Potency 44668.4 nM None
Homo sapiens Matrix metalloproteinase-1 IC50 3252.67 nM 10.1016/j.bmcl.2013.01.027
Homo sapiens Matrix metalloproteinase-2 IC50 9.13 nM 10.1016/j.bmcl.2013.01.027
Homo sapiens Matrix metalloproteinase 9 IC50 8.19 nM 10.1016/j.bmcl.2013.01.027
Homo sapiens microRNA 21 Potency 3689.8 nM None
Homo sapiens MMP-1/MMP-2 Ratio IC50 356.0 None 10.1016/j.bmcl.2013.01.027
Homo sapiens Parathyroid hormone receptor Potency 14125.4 nM None
Homo sapiens Runt-related transcription factor 1/Core-binding factor subunit beta Potency 31622.8 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 9200.0 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 11582.1 nM None
Photinus pyralis Luciferin 4-monooxygenase Potency 19011.5 nM None
Plasmodium falciparum Plasmodium falciparum Potency 82.8 nM None
Plasmodium falciparum Plasmodium falciparum Potency 928.5 nM None
Streptococcus Streptococcus EC50 150000.0 nM None
Streptococcus pyogenes serotype M1 Streptokinase A EC50 48666.0 nM None
Streptococcus pyogenes serotype M1 Streptokinase A EC50 150000.0 nM None
Streptococcus sp. 'group A' Streptococcus sp. 'group A' EC50 150000.0 nM None
Trypanosoma brucei brucei Phosphoglycerate kinase, glycosomal Potency 28183.8 nM None
Trypanosoma brucei brucei (strain 927/4 GUTat10.1) Phosphoglycerate kinase Potency 20574.9 nM None
None Unchecked Potency 3981.1 nM None
None Unchecked Potency 8912.5 nM None
None Unchecked Potency 12589.3 nM None
None Unchecked Potency 56234.1 nM None
None Unchecked Ratio IC50 397.0 None 10.1016/j.bmcl.2013.01.027

Metabolism Information