(5R,8'R)-8'-hydroxy-6-methyl-2',7,8,8'-tetrahydro-2H-spiro[[1,3]dioxolo[4,5-g]isoquinoline-5,7'-indeno[4,5-d][1,3]dioxole]-6'-one
AlkaPlorer ID: AK319075
Synonym: None
IUPAC Name: (5R,8'S)-8'-hydroxy-6-methylspiro[7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline-5,7'-8H-cyclopenta[g][1,3]benzodioxole]-6'-one
Structure
SMILES: CN1CCC2=CC3=C(C=C2[C@@]12C(=O)C1=CC=C4OCOC4=C1[C@@H]2O)OCO3
InChI: InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(26-8-25-14)7-12(10)20(21)18(22)11-2-3-13-17(27-9-24-13)16(11)19(20)23/h2-3,6-7,19,23H,4-5,8-9H2,1H3/t19-,20-/m0/s1
InChIKey: BQZZTMXCHPNTCL-PMACEKPBSA-N
Reference
Alkaloids ofCorydalis pseudoadunca
PubChem CID: 11728283
LOTUS: LTS0227710
NPASS: NPC206625
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Corydalis mucronifera | Corydalis | Papaveraceae | Ranunculales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 367.3570000000001
TPSA？: 77.46000000000001
MolLogP？: 1.7571
Number of H-Donors: 1
Number of H-Acceptors: 7
RingCount: 6
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Acetylcholinesterase | IC50 | 100000.0 | nM | 10.1021/acs.jnatprod.7b00847 |