Molecule

Formosusin A

AlkaPlorer ID: AK319611

Synonym: None

IUPAC Name: 1-[(2Z,4E,6E,8R)-8-hydroxy-6-methyldodeca-2,4,6-trienoyl]pyrrolidin-2-one

Structure

SMILES: CCCC[C@@H](O)/C=C(C)/C=C/C=C\C(=O)N1CCCC1=O

InChI: InChI=1S/C17H25NO3/c1-3-4-9-15(19)13-14(2)8-5-6-10-16(20)18-12-7-11-17(18)21/h5-6,8,10,13,15,19H,3-4,7,9,11-12H2,1-2H3/b8-5+,10-6-,14-13+/t15-/m1/s1

InChIKey: ZYPGADGCNXOUJP-FMHFZIMOSA-N

Reference

PubChem CID: 76332847

NPASS: NPC277341

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
None	Paecilomyces	Thermoascaceae	Eurotiales	Eurotiomycetes	Ascomycota	Fungi	Eukaryota

Properties Information

Molecule Weight: 291.391

TPSA？: 57.61

MolLogP？: 2.7452000000000014

Number of H-Donors: 1

Number of H-Acceptors: 3

RingCount: 1

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Bos taurus	Deoxyribonuclease-1	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Bos taurus	DNA nucleotidylexotransferase	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Drosophila melanogaster	DNA polymerase alpha catalytic subunit	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Drosophila melanogaster	DNA polymerase delta catalytic subunit	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Enterobacteria phage T4	DNA polymerase	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Enterobacteria phage T4	Polynucleotide kinase	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Enterobacteria phage T7	DNA-directed RNA polymerase	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Homo sapiens	DNA-directed DNA/RNA polymerase mu	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Homo sapiens	DNA polymerase delta subunit 1	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Homo sapiens	DNA polymerase eta	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Homo sapiens	DNA polymerase kappa	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Homo sapiens	DNA polymerase lambda	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Human immunodeficiency virus 1	Human immunodeficiency virus type 1 reverse transcriptase	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Mus musculus	DNA polymerase lambda	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Mus musculus	Inosine-5'-monophosphate dehydrogenase 2	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038
Rattus norvegicus	DNA polymerase beta	IC50	35600.0	nM	10.1016/j.bmc.2013.12.038
Rattus norvegicus	DNA polymerase beta	Inhibition	nan	%	10.1016/j.bmc.2013.12.038
Rattus norvegicus	DNA polymerase beta	Ki	5500.0	nM	10.1016/j.bmc.2013.12.038
Rattus norvegicus	DNA polymerase beta	Ki	11600.0	nM	10.1016/j.bmc.2013.12.038
None	Unchecked	IC50	200000.0	nM	10.1016/j.bmc.2013.12.038