None
AlkaPlorer ID: AK319667
Synonym: None
IUPAC Name: (2R,3E,12bS)-3-ethylidene-2-(2-hydroxyethyl)-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-9-ol
Structure
SMILES: C/C=C1/CN2CCC3=C(NC4=CC=C(O)C=C34)[C@@H]2C[C@@H]1CCO
InChI: InChI=1S/C19H24N2O2/c1-2-12-11-21-7-5-15-16-10-14(23)3-4-17(16)20-19(15)18(21)9-13(12)6-8-22/h2-4,10,13,18,20,22-23H,5-9,11H2,1H3/b12-2-/t13-,18-/m0/s1
InChIKey: KLYKGWYHZKEJOS-PYTRYUTRSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Picralima nitida | Picralima | Apocynaceae | Gentianales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 312.41300000000007
TPSA？: 59.49000000000001
MolLogP？: 3.121300000000002
Number of H-Donors: 3
Number of H-Acceptors: 3
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | MRC5 | IC50 | 50000.0 | nM | 10.1021/acs.jnatprod.9b01247 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 99000.0 | nM | 10.1021/acs.jnatprod.9b01247 |