(2R)-6-hydroxy-2-(2-hydroxypropan-2-yl)-9-methyl-2H,3H-furo[2,3-b]quinolin-4-one
AlkaPlorer ID: AK320613
Synonym: None
IUPAC Name: 6-hydroxy-2-(2-hydroxypropan-2-yl)-9-methyl-2,3-dihydrofuro[2,3-b]quinolin-4-one
Structure
SMILES: CN1C2=C(CC(C(C)(C)O)O2)C(=O)C2=CC(O)=CC=C21
InChI: InChI=1S/C15H17NO4/c1-15(2,19)12-7-10-13(18)9-6-8(17)4-5-11(9)16(3)14(10)20-12/h4-6,12,17,19H,7H2,1-3H3
InChIKey: ONPUKGULNMQBLF-UHFFFAOYSA-N
Reference
Quinoline Alkaloids From the Heartwood of Balfourodendron riedelianum
PubChem CID: 336321
CAS: 6872-52-2
LOTUS: LTS0163391
NPASS: NPC320858
COCONUT: CNP0380577.2
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Ruta graveolens | Ruta | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 275.304
TPSA？: 71.69
MolLogP？: 1.3185
Number of H-Donors: 2
Number of H-Acceptors: 5
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Mus musculus | N1E-115 | BK | 7.0 | % | 10.1021/jm001007u |
| Mus musculus | N1E-115 | BNa | 13.0 | % | 10.1021/jm001007u |
| Mus musculus | Voltage-gated potassium channel subunit Kv1.3 | BK | nan | None | 10.1021/jm001007u |