Molecule

Uridin

AlkaPlorer ID: AK320702

Synonym: None

IUPAC Name: 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

Structure

SMILES: O=C1N=C(O)C=CN1C1OC(CO)C(O)C1O

InChI: InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)

InChIKey: DRTQHJPVMGBUCF-UHFFFAOYSA-N

Reference

Metabolites produced by an endophyte Alternaria alternata isolated from Maytenus hookeri

PubChem CID: 1177

CAS: 58-96-8

LOTUS: LTS0075646

COCONUT: CNP0230441.11

data_source: manually

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Rehmannia glutinosa	Rehmannia	Orobanchaceae	Lamiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Pseudostellaria heterophylla	Pseudostellaria	Caryophyllaceae	Caryophyllales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Ophiopogon japonicus	Ophiopogon	Asparagaceae	Asparagales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Panax ginseng	Panax	Araliaceae	Apiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Atractylodes lancea	Atractylodes	Asteraceae	Asterales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Angelica sinensis	Angelica	Apiaceae	Apiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Glehnia littoralis	Glehnia	Apiaceae	Apiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota
Anethum graveolens	Anethum	Apiaceae	Apiales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota

Properties Information

Molecule Weight: 244.203

TPSA？: 125.04

MolLogP？: -2.4396

Number of H-Donors: 4

Number of H-Acceptors: 8

RingCount: 2

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Homo sapiens	786-0	GI50	10000.0	nM	None
Homo sapiens	786-0	GI50	1000000.0	nM	None
Homo sapiens	A498	GI50	1698.24	nM	None
Homo sapiens	A498	GI50	1000000.0	nM	None
Homo sapiens	A549	GI50	10000.0	nM	None
Homo sapiens	A549	GI50	1000000.0	nM	None
Homo sapiens	ACHN	GI50	10000.0	nM	None
Homo sapiens	ACHN	GI50	1000000.0	nM	None
Homo sapiens	BT-549	GI50	1000000.0	nM	None
Homo sapiens	CAKI-1	GI50	1000000.0	nM	None
Homo sapiens	CCRF-CEM	GI50	10000.0	nM	None
Homo sapiens	CCRF-CEM	GI50	1000000.0	nM	None
Homo sapiens	COLO 205	GI50	10000.0	nM	None
Homo sapiens	COLO 205	GI50	1000000.0	nM	None
Homo sapiens	DU-145	GI50	1000000.0	nM	None
Homo sapiens	EKVX	GI50	10000.0	nM	None
Homo sapiens	EKVX	GI50	1000000.0	nM	None
Homo sapiens	HCC 2998	GI50	10000.0	nM	None
Homo sapiens	HCC 2998	GI50	1000000.0	nM	None
Homo sapiens	HCT-116	GI50	10000.0	nM	None
Homo sapiens	HCT-116	GI50	1000000.0	nM	None
Homo sapiens	HCT-15	GI50	10000.0	nM	None
Homo sapiens	HCT-15	GI50	1000000.0	nM	None
Homo sapiens	HL-60	GI50	10000.0	nM	None
Homo sapiens	HL-60	GI50	1000000.0	nM	None
Homo sapiens	HOP-62	GI50	10000.0	nM	None
Homo sapiens	HOP-62	GI50	1000000.0	nM	None
Homo sapiens	HOP-92	GI50	10000.0	nM	None
Homo sapiens	HOP-92	GI50	1000000.0	nM	None
Homo sapiens	Hs-578T	GI50	10000.0	nM	None
Homo sapiens	Hs-578T	GI50	1000000.0	nM	None
Homo sapiens	HT-29	GI50	10000.0	nM	None
Homo sapiens	HT-29	GI50	1000000.0	nM	None
Homo sapiens	IGROV-1	GI50	10000.0	nM	None
Homo sapiens	IGROV-1	GI50	1000000.0	nM	None
Homo sapiens	K562	GI50	10000.0	nM	None
Homo sapiens	K562	GI50	1000000.0	nM	None
Homo sapiens	KM12	GI50	10000.0	nM	None
Homo sapiens	KM12	GI50	1000000.0	nM	None
Homo sapiens	LOX IMVI	GI50	10000.0	nM	None
Homo sapiens	LOX IMVI	GI50	1000000.0	nM	None
Homo sapiens	M14	GI50	1000000.0	nM	None
Homo sapiens	Malme-3M	GI50	10000.0	nM	None
Homo sapiens	Malme-3M	GI50	739605.28	nM	None
Homo sapiens	MCF7	GI50	10000.0	nM	None
Homo sapiens	MCF7	GI50	1000000.0	nM	None
Homo sapiens	MDA-MB-231	GI50	1000000.0	nM	None
Homo sapiens	MDA-MB-435	GI50	10000.0	nM	None
Homo sapiens	MDA-MB-435	GI50	1000000.0	nM	None
Homo sapiens	MDA-N	GI50	10000.0	nM	None
Homo sapiens	MDA-N	GI50	1000000.0	nM	None
Homo sapiens	MOLT-4	GI50	10000.0	nM	None
Homo sapiens	MOLT-4	GI50	831763.77	nM	None
Homo sapiens	NCI/ADR-RES	GI50	10000.0	nM	None
Homo sapiens	NCI/ADR-RES	GI50	1000000.0	nM	None
Homo sapiens	NCI-H226	GI50	1000000.0	nM	None
Homo sapiens	NCI-H23	GI50	10000.0	nM	None
Homo sapiens	NCI-H23	GI50	1000000.0	nM	None
Homo sapiens	NCI-H322M	GI50	10000.0	nM	None
Homo sapiens	NCI-H322M	GI50	1000000.0	nM	None
Homo sapiens	NCI-H460	GI50	10000.0	nM	None
Homo sapiens	NCI-H460	GI50	1000000.0	nM	None
Homo sapiens	NCI-H522	GI50	1000000.0	nM	None
Homo sapiens	OVCAR-3	GI50	10000.0	nM	None
Homo sapiens	OVCAR-3	GI50	1000000.0	nM	None
Homo sapiens	OVCAR-4	GI50	10000.0	nM	None
Homo sapiens	OVCAR-4	GI50	1000000.0	nM	None
Homo sapiens	OVCAR-5	GI50	1000000.0	nM	None
Homo sapiens	OVCAR-8	GI50	10000.0	nM	None
Homo sapiens	OVCAR-8	GI50	1000000.0	nM	None
Homo sapiens	PC-3	GI50	10000.0	nM	None
Homo sapiens	PC-3	GI50	1000000.0	nM	None
Homo sapiens	RPMI-8226	GI50	10000.0	nM	None
Homo sapiens	RPMI-8226	GI50	1000000.0	nM	None
Homo sapiens	RXF 393	GI50	10000.0	nM	None
Homo sapiens	RXF 393	GI50	1000000.0	nM	None
Homo sapiens	SF-268	GI50	10000.0	nM	None
Homo sapiens	SF-268	GI50	1000000.0	nM	None
Homo sapiens	SF-295	GI50	10000.0	nM	None
Homo sapiens	SF-295	GI50	1000000.0	nM	None
Homo sapiens	SF-539	GI50	10000.0	nM	None
Homo sapiens	SF-539	GI50	1000000.0	nM	None
Homo sapiens	SK-MEL-2	GI50	10000.0	nM	None
Homo sapiens	SK-MEL-2	GI50	1000000.0	nM	None
Homo sapiens	SK-MEL-28	GI50	10000.0	nM	None
Homo sapiens	SK-MEL-28	GI50	1000000.0	nM	None
Homo sapiens	SK-MEL-5	GI50	10000.0	nM	None
Homo sapiens	SK-MEL-5	GI50	1000000.0	nM	None
Homo sapiens	SK-OV-3	GI50	10000.0	nM	None
Homo sapiens	SK-OV-3	GI50	1000000.0	nM	None
Homo sapiens	SN12C	GI50	10000.0	nM	None
Homo sapiens	SN12C	GI50	1000000.0	nM	None
Homo sapiens	SNB-19	GI50	10000.0	nM	None
Homo sapiens	SNB-19	GI50	1000000.0	nM	None
Homo sapiens	SNB-75	GI50	10000.0	nM	None
Homo sapiens	SNB-75	GI50	788860.12	nM	None
Homo sapiens	SR	GI50	10000.0	nM	None
Homo sapiens	SR	GI50	1000000.0	nM	None
Homo sapiens	SW-620	GI50	10000.0	nM	None
Homo sapiens	SW-620	GI50	1000000.0	nM	None
Homo sapiens	T47D	GI50	10000.0	nM	None
Homo sapiens	T47D	GI50	1000000.0	nM	None
Homo sapiens	TK-10	GI50	10000.0	nM	None
Homo sapiens	TK-10	GI50	1000000.0	nM	None
Homo sapiens	U-251	GI50	10000.0	nM	None
Homo sapiens	U-251	GI50	1000000.0	nM	None
Homo sapiens	UACC-257	GI50	1000000.0	nM	None
Homo sapiens	UACC-62	GI50	10000.0	nM	None
Homo sapiens	UACC-62	GI50	1000000.0	nM	None
Homo sapiens	UO-31	GI50	165.2	nM	None
Homo sapiens	UO-31	GI50	905732.6	nM	None
None	NON-PROTEIN TARGET	Potency	595.2	nM	None
None	NON-PROTEIN TARGET	Potency	667.8	nM	None

Metabolism Information

AKRT ID	Reaction	Reaction Link ID
AKRT024384	O=c1ccn(C2OC(CO)C(O)C2O)c(=O)[nH]1>>Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1	MNXR130941