Molecule

None

AlkaPlorer ID: AK321845

Synonym: None

IUPAC Name: 2-aminobicyclo[2.2.1]heptane-2-carboxylic acid

SMILES: NC1(C(=O)O)CC2CCC1C2

InChI: InChI=1S/C8H13NO2/c9-8(7(10)11)4-5-1-2-6(8)3-5/h5-6H,1-4,9H2,(H,10,11)

InChIKey: MPUVBVXDFRDIPT-UHFFFAOYSA-N

PubChem CID: 115288

CAS: 20448-79-7

NPASS: NPC330633

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain

Molecule Weight: 155.19699999999995

TPSA？: 63.32000000000001

MolLogP？: 0.5884999999999994

Number of H-Donors: 2

Number of H-Acceptors: 2

RingCount: 2

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Homo sapiens	L-type amino acid transporter 1	Activity	3.13	%	10.1021/acs.jmedchem.6b00190
Homo sapiens	L-type amino acid transporter 1	Activity	30.8	%	10.1021/acs.jmedchem.6b00190
Homo sapiens	L-type amino acid transporter 1	Activity	35.9	%	10.1021/acs.jmedchem.6b00190
Homo sapiens	L-type amino acid transporter 1	Activity	42.7	%	10.1021/acs.jmedchem.6b00190
Homo sapiens	L-type amino acid transporter 1	Activity	nan	None	10.1021/acs.jmedchem.6b00190
Homo sapiens	L-type amino acid transporter 1	Drug uptake	11.95	nmol	10.1021/acs.jmedchem.6b00190
Homo sapiens	L-type amino acid transporter 1	IC50	112000.0	nM	10.1021/acs.jmedchem.6b00190
Homo sapiens	L-type amino acid transporter 1	Ratio IC50	6.0	None	10.1021/acs.jmedchem.6b00190
Homo sapiens	L-type amino acid transporter 3	Inhibition	40.2	%	10.1021/acs.jnatprod.6b00190
Homo sapiens	MCF7	Activity	13.9	%	10.1021/acs.jmedchem.6b00190
Homo sapiens	MCF7	Activity	24.1	%	10.1021/acs.jmedchem.6b00190
Homo sapiens	MCF7	Activity	nan	None	10.1021/acs.jmedchem.6b00190
Homo sapiens	MCF7	IC50	362000.0	nM	10.1021/acs.jmedchem.6b00190
Homo sapiens	Sodium-dependent neutral amino acid transporter B(0)AT2	Inhibition	80.0	%	10.1021/jm501086v
Rattus norvegicus	Monocarboxylate transporter 10	Activity	nan	None	10.1074/jbc.m009462200
None	Unchecked	IC50	4060000.0	nM	10.1021/np500968t