(2E)-3-(2-imino-2,3-dihydro-1H-imidazol-4-yl)prop-2-en-1-amine
AlkaPlorer ID: AK321902
Synonym: None
IUPAC Name: 5-[(E)-3-aminoprop-1-enyl]-1H-imidazol-2-amine
Structure
SMILES: N=C1NC=C(/C=C/CN)N1
InChI: InChI=1S/C6H10N4/c7-3-1-2-5-4-9-6(8)10-5/h1-2,4H,3,7H2,(H3,8,9,10)/b2-1+
InChIKey: YFJXNGUQXKFQAO-OWOJBTEDSA-N
Source
Properties Information
Molecule Weight: 138.174
TPSA？: 81.44999999999999
MolLogP？: -0.20583
Number of H-Donors: 4
Number of H-Acceptors: 2
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Leishmania donovani | Leishmania donovani | IC50 | 13.1 | ug.mL-1 | 10.1016/j.bmc.2007.07.032 |
| Plasmodium falciparum | Enoyl-acyl-carrier protein reductase | IC50 | 100.0 | ug.mL-1 | 10.1016/j.bmc.2007.07.032 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 7.4 | ug.mL-1 | 10.1016/j.bmc.2007.07.032 |
| Rattus norvegicus | L6 | IC50 | 0.7 | ug.mL-1 | 10.1016/j.bmc.2007.07.032 |
| Trypanosoma brucei rhodesiense | Trypanosoma brucei rhodesiense | IC50 | 2.4 | ug.mL-1 | 10.1016/j.bmc.2007.07.032 |
| Trypanosoma cruzi | Trypanosoma cruzi | IC50 | 2.5 | ug.mL-1 | 10.1016/j.bmc.2007.07.032 |