Stemocurtisine
AlkaPlorer ID: AK321940
Synonym: None
IUPAC Name: (5Z)-4-methoxy-3-methyl-5-[(1R,9S,10R,11R,12S)-12-methyl-14,15-dioxa-5-azatetracyclo[7.5.1.01,11.05,10]pentadecan-13-ylidene]furan-2-one
Structure
SMILES: COC1=C(C)C(=O)O/C1=C1\O[C@@]23CCCN4CCC[C@H](O2)[C@H]4[C@H]3[C@@H]1C
InChI: InChI=1S/C19H25NO5/c1-10-13-14-12-6-4-8-20(14)9-5-7-19(13,24-12)25-16(10)17-15(22-3)11(2)18(21)23-17/h10,12-14H,4-9H2,1-3H3/b17-16-/t10-,12-,13+,14-,19+/m0/s1
InChIKey: LXAQGNNSRKLTLE-KDZIKLRDSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Stemona curtisii | Stemona | Stemonaceae | Pandanales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 347.411
TPSA？: 57.23
MolLogP？: 2.311
Number of H-Donors: 0
Number of H-Acceptors: 6
RingCount: 5
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Anopheles minimus | Anopheles minimus | LC50 | 18.0 | ppm | 10.1021/np034066u |
| Homo sapiens | Acetylcholinesterase | MIC | 2.88 | nM | 10.1021/np100474y |
| Homo sapiens | Acetylcholinesterase | MIC | 1000.0 | ng | 10.1021/np100474y |