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name Structure Reference Source Properties Activities Metabolism

Chloroquine

AlkaPlorer ID: AK322548

Synonym: None

IUPAC Name: 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine

Structure

SMILES: CCN(CC)CCCC(C)NC1=CC=NC2=CC(Cl)=CC=C12

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InChI: InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)

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InChIKey: WHTVZRBIWZFKQO-UHFFFAOYSA-N

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Properties Information

Molecule Weight: 319.88000000000005

TPSA？: 28.16

MolLogP？: 4.810600000000004

Number of H-Donors: 1

Number of H-Acceptors: 3

RingCount: 2

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Acinetobacter baumannii Acinetobacter baumannii MIC 20000.0 nM 10.6019/CHEMBL4513161
Aspergillus fumigatus Aspergillus fumigatus Activity nan None 10.1016/j.bmc.2006.10.006
Bacteria DNA log K nan None 10.1016/j.ejmech.2018.02.021
Betapolyomavirus hominis BK polyomavirus EC50 1700.0 nM 10.1128/aac.00843-07
Bos taurus Calf thymus DNA Delta Tm 4.0 degrees C 10.1016/j.ejmech.2018.02.021
Bos taurus Calf thymus DNA log K nan None 10.1016/j.ejmech.2018.02.021
Bos taurus Dihydrofolate reductase IC50 0.01 ug.mL-1 10.1016/j.bmc.2017.10.041
Bos taurus Dihydrofolate reductase IC50 0.01 ug.mL-1 10.1016/j.bmc.2019.06.038
Bos taurus Dihydrofolate reductase IC50 0.01 ug.mL-1 10.1016/j.ejmech.2017.02.012
Bos taurus Dihydrofolate reductase IC50 30.1 nM 10.1016/j.bmc.2017.05.054
Bos taurus Dihydrofolate reductase IC50 30.1 nM 10.1016/j.bmc.2017.07.057
Bos taurus DNA Delta Tm 9.0 degrees C 10.1016/j.ejmech.2013.05.046
Bos taurus DNA log K nan None 10.1016/j.ejmech.2013.05.046
Candida albicans Candida albicans FICI 0.156 None 10.1021/acs.jmedchem.6b01203
Candida albicans Candida albicans IC50 nan None 10.1016/j.bmc.2006.10.006
Candida albicans Candida albicans MIC 200.0 ug.mL-1 10.1016/j.bmcl.2007.09.056
Candida albicans Candida albicans MIC 20000.0 nM 10.6019/CHEMBL4513161
Canis lupus familiaris Canis familiaris Methemoglobin nan None 10.1016/S0960-894X(97)10074-9
Canis lupus familiaris Canis familiaris Methemoglobin nan None 10.1016/s0960-894x(99)00058-x
Canis lupus familiaris MDCK CC50 55600.0 nM 10.1016/j.ejmech.2015.06.024
Canis lupus familiaris MDCK MCC 100000.0 nM 10.1016/j.ejmech.2015.06.024
Canis lupus familiaris MDCK Papp 13.0 ucm/s 10.1016/j.bmc.2013.09.065
Canis lupus familiaris MDCK Papp 14.0 ucm/s 10.1016/j.bmc.2013.09.065
Canis lupus familiaris MDCK Ratio 1.08 None 10.1016/j.bmc.2013.09.065
Carica papaya Papain IC50 nan None 10.1016/j.ejmech.2013.08.037
Chikungunya virus Chikungunya virus EC50 11000.0 nM 10.1016/j.bmc.2018.01.002
Chikungunya virus Chikungunya virus EC50 11000.0 nM 10.1016/j.ejmech.2018.02.054
Chikungunya virus Chikungunya virus EC50 11000.0 nM 10.1021/acs.jnatprod.7b00233
Chikungunya virus Chikungunya virus EC50 11000.0 nM 10.1021/acs.jnatprod.8b00800
Chikungunya virus Chikungunya virus EC90 21.0 uM 10.1016/j.bmc.2018.01.002
Chikungunya virus Chikungunya virus EC90 21.0 uM 10.1016/j.ejmech.2018.02.054
Chlorocebus sabaeus Vero Activity 500.0 nM 10.1128/aac.00951-09
Chlorocebus sabaeus Vero Activity nan None 10.1016/j.bmc.2008.05.079
Chlorocebus sabaeus Vero Activity nan None 10.1016/j.bmc.2009.06.020
Chlorocebus sabaeus Vero Activity nan None 10.1016/j.bmcl.2007.12.069
Chlorocebus sabaeus Vero Activity nan None 10.1016/j.bmcl.2009.01.103
Chlorocebus sabaeus Vero Activity nan None 10.1016/j.bmcl.2012.11.004
Chlorocebus sabaeus Vero Activity nan None 10.1016/j.ejmech.2011.04.002
Chlorocebus sabaeus Vero Activity nan None 10.1016/j.ejmech.2014.10.061
Chlorocebus sabaeus Vero Activity nan None 10.1016/j.ejmech.2017.02.024
Chlorocebus sabaeus Vero Activity nan None 10.1016/j.ejmech.2017.03.007
Chlorocebus sabaeus Vero Activity nan None 10.1016/j.ejmech.2018.11.021
Chlorocebus sabaeus Vero Activity nan None 10.1021/ml3000808
Chlorocebus sabaeus Vero Activity nan None 10.1021/np020592u
Chlorocebus sabaeus Vero Activity nan None 10.1021/np030045o
Chlorocebus sabaeus Vero Activity nan None 10.1021/np030086k
Chlorocebus sabaeus Vero Activity nan None 10.1021/np0400095
Chlorocebus sabaeus Vero Activity nan None 10.1128/aac.01304-08
Chlorocebus sabaeus Vero CC50 75.0 ug.mL-1 10.1016/j.bmcl.2012.10.101
Chlorocebus sabaeus Vero CC50 25000.0 nM 10.1016/j.bmcl.2020.127667
Chlorocebus sabaeus Vero CC50 25000.0 nM 10.1016/j.bmcl.2023.129214
Chlorocebus sabaeus Vero CC50 75000.0 nM 10.1016/j.ejmech.2017.07.052
Chlorocebus sabaeus Vero CC50 89000.0 nM 10.1016/j.bmc.2018.01.002
Chlorocebus sabaeus Vero CC50 89000.0 nM 10.1016/j.ejmech.2018.02.054
Chlorocebus sabaeus Vero CC50 89000.0 nM 10.1021/acs.jnatprod.5b00116
Chlorocebus sabaeus Vero CC50 89000.0 nM 10.1021/acs.jnatprod.8b00800
Chlorocebus sabaeus Vero CC50 89000.0 nM 10.1021/jm401844c
Chlorocebus sabaeus Vero CC50 89000.0 nM 10.1021/np300637t
Chlorocebus sabaeus Vero CC50 89000.0 nM 10.1021/np500271u
Chlorocebus sabaeus Vero CC50 94950.0 nM 10.1021/acs.jmedchem.9b00775
Chlorocebus sabaeus Vero CC50 100000.0 nM 10.1021/acs.jmedchem.0c00502
Chlorocebus sabaeus Vero CC50 125000.0 nM 10.1016/j.bmcl.2015.08.030
Chlorocebus sabaeus Vero CC50 125900.0 nM 10.1016/j.ejmech.2012.12.019
Chlorocebus sabaeus Vero CC50 150000.0 nM 10.1101/2020.03.20.999730
Chlorocebus sabaeus Vero CC50 226000.0 nM 10.1016/j.ejmech.2017.03.010
Chlorocebus sabaeus Vero CC50 226700.0 nM 10.1016/j.ejmech.2020.113084
Chlorocebus sabaeus Vero CC50 412000.0 nM 10.1016/j.ejmech.2016.12.058
Chlorocebus sabaeus Vero CC50 412000.0 nM 10.1016/j.ejmech.2017.01.007
Chlorocebus sabaeus Vero CC50 500000.0 nM 10.1016/j.ejmech.2018.06.042
Chlorocebus sabaeus Vero CC50 500000.0 nM 10.1016/j.ejmech.2018.11.008
Chlorocebus sabaeus Vero CC50 684680.0 nM 10.1021/ml500211c
Chlorocebus sabaeus Vero CC50 nan None 10.1016/j.bmcl.2017.12.060
Chlorocebus sabaeus Vero CC50 nan None 10.1016/j.ejmech.2017.04.063
Chlorocebus sabaeus Vero IC50 4.7 ug.mL-1 10.1016/j.bmc.2006.10.062
Chlorocebus sabaeus Vero IC50 10.0 ug.mL-1 10.1021/np030524n
Chlorocebus sabaeus Vero IC50 48.5 ug.mL-1 10.1021/np800333r
Chlorocebus sabaeus Vero IC50 14880.0 nM 10.1016/j.ejmech.2016.11.057
Chlorocebus sabaeus Vero IC50 21000.0 nM 10.1016/j.ejmech.2013.04.066
Chlorocebus sabaeus Vero IC50 50000.0 nM 10.1016/j.bmc.2012.05.061
Chlorocebus sabaeus Vero IC50 234470.0 nM 10.1016/j.bmcl.2015.09.033
Chlorocebus sabaeus Vero IC50 234470.0 nM 10.1016/j.bmcl.2015.12.080
Chlorocebus sabaeus Vero IC50 nan None 10.1007/s00044-011-9798-7
Chlorocebus sabaeus Vero IC50 nan None 10.1016/j.bmc.2006.10.006
Chlorocebus sabaeus Vero IC50 nan None 10.1016/j.bmc.2009.10.042
Chlorocebus sabaeus Vero IC50 nan None 10.1016/j.bmc.2010.06.066
Chlorocebus sabaeus Vero IC50 nan None 10.1016/j.bmc.2017.10.041
Chlorocebus sabaeus Vero IC50 nan None 10.1016/j.bmc.2019.06.038
Chlorocebus sabaeus Vero IC50 nan None 10.1016/j.ejmech.2010.03.006
Chlorocebus sabaeus Vero IC50 nan None 10.1016/j.ejmech.2014.10.061
Chlorocebus sabaeus Vero IC50 nan None 10.1016/j.ejmech.2015.05.020
Chlorocebus sabaeus Vero IC50 nan None 10.1016/j.ejmech.2018.02.021
Chlorocebus sabaeus Vero IC50 nan None 10.1021/acsmedchemlett.9b00521
Chlorocebus sabaeus Vero IC50 nan None 10.1021/jm100507q
Chlorocebus sabaeus Vero IC50 nan None 10.1021/jm900672t
Chlorocebus sabaeus Vero IC50 nan None 10.1021/np050484i
Chlorocebus sabaeus Vero IC50 nan None 10.1021/np0601399
Chlorocebus sabaeus Vero IC50 nan None 10.1021/np1000939
Chlorocebus sabaeus Vero IC50 nan None 10.1021/np2004825
Chlorocebus sabaeus Vero IC50 nan None 10.1021/np200940b
Chlorocebus sabaeus Vero IC50 nan None 10.1021/np300638f
Chlorocebus sabaeus Vero IC50 nan None 10.1021/np800653z
Chlorocebus sabaeus Vero IC50 nan None 10.1021/np960013j
Chlorocebus sabaeus Vero IC50 nan None 10.1039/C3MD00097D
Chlorocebus sabaeus Vero Inhibition nan % 10.1021/np900334k
Chlorocebus sabaeus Vero MCC 100000.0 nM 10.1016/j.ejmech.2015.06.024
Chlorocebus sabaeus Vero TC50 14881.0 nM 10.1021/acs.jmedchem.5b01380
Chlorocebus sabaeus Vero TC50 14881.0 uM 10.1016/j.bmc.2008.11.050
Chlorocebus sabaeus Vero TC50 14881.0 uM 10.1016/j.bmc.2009.10.019
Chlorocebus sabaeus Vero TC50 nan None 10.1021/np800163u
Chlorocebus sabaeus Vero C1008 CC50 38700.0 nM 10.6019/CHEMBL4651402
Chlorocebus sabaeus Vero C1008 CC50 83400.0 nM 10.1021/acsmedchemlett.2c00123
Chlorocebus sabaeus Vero C1008 CC50 100000.0 nM 10.1016/j.ejmech.2020.112559
Chlorocebus sabaeus Vero C1008 CC50 100000.0 nM 10.1016/j.ejmech.2020.112687
Chlorocebus sabaeus Vero C1008 CC50 100000.0 nM 10.1016/j.ejmech.2021.113157
Chlorocebus sabaeus Vero C1008 CC50 100000.0 nM 10.1021/acs.jmedchem.0c00626
Chlorocebus sabaeus Vero C1008 CC50 128000.0 nM 10.1021/acs.jmedchem.0c00626
Chlorocebus sabaeus Vero C1008 CC50 249500.0 nM 10.1016/j.ejmech.2021.113220
Chlorocebus sabaeus Vero C1008 CC50 261000.0 nM 10.1021/acs.jmedchem.0c00626
Chlorocebus sabaeus Vero C1008 FC 9.0 None 10.1021/acsmedchemlett.2c00123
Chlorocebus sabaeus Vero C1008 pCC50 4.41 None 10.6019/CHEMBL4651402
Chromobacterium violaceum Chromobacterium violaceum Activity 10.1 % 10.1016/j.bmcl.2020.127336
Chromobacterium violaceum Chromobacterium violaceum Activity nan None 10.1016/j.bmcl.2020.127336
Clostridium botulinum Botulinum neurotoxin type A Inhibition 6.0 % 10.1021/jm500033r
Coxsackievirus Coxsackievirus EC50 100000.0 nM 10.1016/j.ejmech.2015.06.024
Cricetulus griseus CHO CC50 155000.0 nM 10.1016/j.ejmech.2015.03.011
Cricetulus griseus CHO IC50 35800.0 nM 10.1016/j.bmcl.2016.01.052
Cricetulus griseus CHO IC50 57840.0 nM 10.1016/j.bmcl.2018.03.026
Cricetulus griseus CHO IC50 nan None 10.1016/j.bmc.2015.07.051
Cricetulus griseus CHO IC50 nan None 10.1016/j.bmcl.2010.09.130
Cricetulus griseus CHO IC50 nan None 10.1016/j.bmcl.2011.01.103
Cricetulus griseus CHO IC50 nan None 10.1016/j.bmcl.2012.10.094
Cricetulus griseus CHO IC50 nan None 10.1016/j.bmcl.2013.12.067
Cricetulus griseus CHO IC50 nan None 10.1021/acsmedchemlett.8b00496
Cricetulus griseus CHO IC50 nan None 10.1039/C3MD20377H
Cricetulus griseus CHO IC50 nan None 10.1039/C7MD00063D
Cricetulus griseus V79 LD50 167.0 uM 10.1021/acsmedchemlett.1c00589
Cryptococcus neoformans Cryptococcus neoformans IC50 nan None 10.1016/j.bmc.2006.10.006
Cryptococcus neoformans Cryptococcus neoformans MIC 20000.0 nM 10.6019/CHEMBL4513161
Cryptosporidium parvum Cryptosporidium parvum IC50 27.0 nM 10.1128/aac.00207-08
dengue virus type 2 dengue virus type 2 EC90 5.04 uM 10.1021/acs.jmedchem.5b01653
Ebolavirus Ebolavirus EC50 16000.0 nM 10.1016/j.ejmech.2018.10.061
Entamoeba histolytica Entamoeba histolytica IC50 9579.0 nM 10.1016/j.bmc.2010.07.008
Enterococcus faecium Enterococcus faecium IC50 6600000.0 nM 10.1021/jm00212a010
Enterococcus faecium Enterococcus faecium IC50 7500000.0 nM 10.1021/jm00212a010
Enterococcus faecium Enterococcus faecium Inhibition nan % 10.1021/jm00212a010
Enterococcus faecium Enterococcus faecium Ratio IC50 1.0 None 10.1021/jm00212a010
Escherichia coli DNA gyrase Inhibition nan % 10.1021/acs.jnatprod.0c01032
Escherichia coli Escherichia coli MIC 20000.0 nM 10.6019/CHEMBL4513161
Gallus gallus Riboflavin-binding protein Kd 2100.0 nM 10.1021/ml100296z
Giardia intestinalis Giardia intestinalis IC50 401.0 nM 10.1016/j.bmc.2010.07.008
Homo sapiens 184B5 IC50 76130.0 nM 10.1016/j.ejmech.2017.05.052
Homo sapiens A2780 IC50 nan None 10.1016/j.bmc.2009.02.022
Homo sapiens A2780 IC50 nan None 10.1021/np200499d
Homo sapiens A-431 ED50 20.0 ug ml-1 10.1021/np50091a005
Homo sapiens A549 IC50 40.0 nM 10.1021/jm030545e
Homo sapiens A549 IC50 100000.0 nM 10.1016/j.ejmech.2021.113685
Homo sapiens Adenosine A1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor Ki 4365.16 nM 10.1038/s41586-020-2286-9
Homo sapiens Alpha-2b adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor Ki 31622.78 nM 10.1038/s41586-020-2286-9
Homo sapiens Alpha-2c adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor Ki 10000.0 nM 10.1038/s41586-020-2286-9
Homo sapiens Amyloid-beta A4 protein Activity 13.0 % 10.1021/acs.jmedchem.7b01417
Homo sapiens Amyloid-beta A4 protein Activity 36.9 % 10.1021/acs.jmedchem.7b01417
Homo sapiens Amyloid-beta A4 protein Activity 68.25 % 10.1016/j.bmc.2015.04.009
Homo sapiens Amyloid-beta A4 protein FC 1.0 None 10.1016/j.bmc.2018.03.016
Homo sapiens Amyloid-beta A4 protein IC50 7000.0 nM 10.1016/j.bmc.2018.03.016
Homo sapiens Amyloid-beta A4 protein IC50 12800.0 nM 10.1016/j.bmc.2018.03.016
Homo sapiens Amyloid-beta A4 protein Inhibition 19.6 % 10.1021/acs.jmedchem.7b01417
Homo sapiens Amyloid-beta A4 protein Inhibition 56.7 % 10.1016/j.bmc.2014.08.035
Homo sapiens Angiotensin-converting enzyme 2 IC50 1130.0 nM 10.1021/acs.jmedchem.0c00502
Homo sapiens Ataxin-2 Potency 14125.4 nM None
Homo sapiens Ataxin-2 Potency 15848.9 nM None
Homo sapiens BEAS-2B IC50 3070.0 nM 10.1016/j.ejmech.2021.113685
Homo sapiens Beta-1 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-secretase 1 IC50 7000.0 nM 10.1016/j.ejmech.2018.08.092
Homo sapiens Beta-secretase 1 IC50 12700.0 nM 10.1016/j.ejmech.2018.08.092
Homo sapiens Beta-secretase 1 Inhibition 50.0 % 10.1016/j.bmc.2018.08.019
Homo sapiens Bile salt export pump AC50 300000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Bile salt export pump IC50 135000.0 nM 10.1093/toxsci/kfq269
Homo sapiens BJ EC50 25000.0 nM 10.1016/j.bmcl.2014.09.061
Homo sapiens Bradykinin B2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens BT-474 EC50 4800.0 nM 10.1016/j.ejmech.2022.114846
Homo sapiens BT-474 IC50 1000000.0 nM 10.1021/acs.jmedchem.7b01019
Homo sapiens BT-549 IC50 nan None 10.1016/j.ejmech.2015.05.020
Homo sapiens BT-549 IC50 nan None 10.1021/np960013j
Homo sapiens BXPC-3 Ratio IC50 1.2 None 10.1021/ml500348p
Homo sapiens Caco-2 GI50 38670.0 nM 10.1016/j.bmcl.2013.10.025
Homo sapiens Canalicular multispecific organic anion transporter 1 Activity 102.0 % 10.1021/jm7015683
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Canalicular multispecific organic anion transporter 2 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Cannabinoid CB1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cathepsin B Inhibition nan % 10.1016/j.ejmech.2018.10.061
Homo sapiens Cathepsin D IC50 nan None 10.1016/j.bmcl.2012.07.069
Homo sapiens CCRF-CEM IC50 23000.0 nM 10.1016/j.ejmech.2015.06.024
Homo sapiens CDGSH iron-sulfur domain-containing protein 1 IC50 nan None 10.1016/j.bmcl.2016.09.009
Homo sapiens CDGSH iron-sulfur domain-containing protein 1 Ki nan None 10.1016/j.bmcl.2016.09.009
Homo sapiens Cholecystokinin A receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens C-X-C chemokine receptor type 4 EC50 6500.0 nM 10.1016/j.ejmech.2018.08.028
Homo sapiens Cyclooxygenase-2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cytochrome P450 1A2 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2B6 Inhibition 112.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 2B6 Inhibition 134.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 2C19 Inhibition 111.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 2C19 Inhibition 113.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 2C19 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2C9 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 2C9 Inhibition 114.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 2C9 Inhibition 128.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 2C9 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 2D6 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 2D6 Inhibition 90.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 2D6 Inhibition 99.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 2D6 Inhibition nan % 10.1021/tx300075j
Homo sapiens Cytochrome P450 3A4 FC 1.0 None 10.1016/j.bmcl.2016.06.088
Homo sapiens Cytochrome P450 3A4 IC50 349945.17 nM 10.1016/j.ejmech.2008.12.004
Homo sapiens Cytochrome P450 3A4 Inhibition 102.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 3A4 Inhibition 105.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 3A4 Inhibition 106.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 3A4 Inhibition 110.0 % 10.1021/jm100057h
Homo sapiens Cytochrome P450 3A4 Inhibition nan % 10.1021/tx300075j
Homo sapiens Daudi TC50 16.7 uM 10.1021/jm801352s
Homo sapiens Daudi TC50 nan None 10.1021/jm701247k
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Equilibrative nucleoside transporter 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Fibrinogen C domain-containing protein 1 Activity nan None None
Homo sapiens Flap endonuclease 1 Potency 89125.1 nM None
Homo sapiens Ghrelin receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HCT-116 Activity nan None 10.1021/acs.jmedchem.2c00432
Homo sapiens HCT-116 IC50 33700.0 nM 10.1021/np020070e
Homo sapiens HCT-8 Activity 5.0 % 10.1128/aac.00207-08
Homo sapiens HCT-8 Activity 12.0 % 10.1128/aac.00207-08
Homo sapiens HCT-8 Activity 15.0 % 10.1128/aac.00207-08
Homo sapiens HEK293 Activity 0.0 % 10.1021/np9002564
Homo sapiens HEK293 Activity 40.0 % 10.1021/acs.jnatprod.9b00933
Homo sapiens HEK293 Activity 51.0 % 10.1021/acs.jnatprod.5b00581
Homo sapiens HEK293 Activity 67.0 % 10.1021/acs.jnatprod.0c00929
Homo sapiens HEK293 Activity nan None 10.1016/j.ejmech.2016.05.069
Homo sapiens HEK293 Activity nan None 10.1021/acs.jmedchem.6b01885
Homo sapiens HEK293 Activity nan None 10.1021/acs.jnatprod.8b00154
Homo sapiens HEK293 CC50 20000.0 nM 10.1016/j.ejmech.2021.113685
Homo sapiens HEK293 CC50 20000.0 nM 10.1021/acs.jmedchem.8b01310
Homo sapiens HEK293 CC50 20000.0 nM 10.6019/CHEMBL4513161
Homo sapiens HEK293 EC50 25000.0 nM 10.1016/j.bmcl.2014.09.061
Homo sapiens HEK293 GI 17.3 % 10.1021/acs.jmedchem.8b01310
Homo sapiens HEK293 GI 53.2 % 10.1021/acs.jnatprod.8b00956
Homo sapiens HEK293 GI 57.0 % 10.1021/acs.jmedchem.8b01310
Homo sapiens HEK293 GI 60.0 % 10.1021/acs.jnatprod.6b00759
Homo sapiens HEK293 GI 60.0 % 10.1021/acs.jnatprod.9b00721
Homo sapiens HEK293 GI nan None 10.1016/j.bmcl.2017.07.039
Homo sapiens HEK293 GI nan None 10.1021/acs.jnatprod.7b00992
Homo sapiens HEK293 IC50 120.0 nM 10.1016/j.bmcl.2016.05.039
Homo sapiens HEK293 IC50 490.0 nM 10.1021/acs.jnatprod.7b00587
Homo sapiens HEK293 IC50 10000.0 nM 10.1021/acs.jnatprod.2c01041
Homo sapiens HEK293 IC50 12000.0 nM 10.1021/np100737q
Homo sapiens HEK293 IC50 40000.0 nM 10.1016/j.bmcl.2017.07.039
Homo sapiens HEK293 IC50 40000.0 nM 10.1021/acs.jnatprod.9b00933
Homo sapiens HEK293 IC50 48000.0 nM 10.1016/j.bmcl.2010.11.081
Homo sapiens HEK293 IC50 101190.0 nM 10.1016/j.ejmech.2021.113330
Homo sapiens HEK293 IC50 1000000.0 nM 10.1021/acs.jmedchem.0c01744
Homo sapiens HEK293 IC50 nan None 10.1016/j.ejmech.2016.12.041
Homo sapiens HEK293 Inhibition 100.0 % 10.6019/CHEMBL2113921
Homo sapiens HEK-293T EC50 nan None 10.1016/j.ejmech.2014.04.076
Homo sapiens HEK-293T EC50 nan None 10.1021/jm4011466
Homo sapiens HEK-293T IC50 50000.0 nM 10.1016/j.ejmech.2013.08.037
Homo sapiens HEL CC50 58500.0 nM 10.1016/j.ejmech.2015.06.024
Homo sapiens HEL MCC 20000.0 nM 10.1016/j.ejmech.2015.06.024
Homo sapiens HEL 299 CC50 33600.0 nM 10.1021/acsmedchemlett.2c00123
Homo sapiens HeLa Activity 3.6 % 10.1016/j.bmcl.2019.05.001
Homo sapiens HeLa Activity 82.0 % 10.1021/jm060736s
Homo sapiens HeLa Activity 92.0 % 10.1016/j.bmcl.2015.04.014
Homo sapiens HeLa Activity 94.0 % 10.1016/j.bmcl.2015.04.014
Homo sapiens HeLa Activity 97.0 % 10.1016/j.bmcl.2015.04.014
Homo sapiens HeLa Activity 98.0 % 10.1016/j.bmcl.2015.04.014
Homo sapiens HeLa Activity 100.0 % 10.1016/j.bmcl.2015.04.014
Homo sapiens HeLa Activity 4300000.0 RLU/mg 10.1021/jm060736s
Homo sapiens HeLa Activity nan None 10.1016/j.bmc.2009.08.054
Homo sapiens HeLa Activity nan None 10.1016/j.ejmech.2018.07.011
Homo sapiens HeLa Activity nan None 10.1016/j.ejmech.2018.10.061
Homo sapiens HeLa CC50 1000.0 ug.mL-1 10.1016/j.bmcl.2015.04.014
Homo sapiens HeLa EC50 19600.0 nM 10.1021/acs.jnatprod.9b00856
Homo sapiens HeLa FC 1.7 None 10.1016/j.ejmech.2018.07.011
Homo sapiens HeLa FC 1.8 None 10.1021/acs.jnatprod.6b00550
Homo sapiens HeLa FC 1.9 None 10.1016/j.ejmech.2018.07.011
Homo sapiens HeLa FC 3.1 None 10.1016/j.ejmech.2018.07.011
Homo sapiens HeLa FC 4.2 None 10.1016/j.ejmech.2018.07.011
Homo sapiens HeLa FC 7.37 None 10.1021/acs.jnatprod.6b00550
Homo sapiens HeLa GI50 2100.0 nM 10.1016/j.bmc.2009.08.054
Homo sapiens HeLa GI50 4400.0 nM 10.1016/j.bmc.2009.08.054
Homo sapiens HeLa GI50 5300.0 nM 10.1016/j.bmc.2009.08.054
Homo sapiens HeLa GI50 5600.0 nM 10.1016/j.bmc.2009.08.054
Homo sapiens HeLa GI50 6100.0 nM 10.1016/j.bmc.2009.08.054
Homo sapiens HeLa GI50 18600.0 nM 10.1016/j.bmc.2009.08.054
Homo sapiens HeLa IC50 8540.0 nM 10.1016/j.ejmech.2021.113408
Homo sapiens HeLa IC50 9665.0 nM 10.1016/j.bmcl.2007.07.049
Homo sapiens HeLa IC50 9670.0 nM 10.1016/j.bmcl.2011.03.090
Homo sapiens HeLa IC50 18000.0 nM 10.1016/j.ejmech.2015.06.024
Homo sapiens HeLa IC50 29960.0 nM 10.1016/j.bmc.2015.11.007
Homo sapiens HeLa IC50 100000.0 nM 10.1016/j.bmc.2012.06.038
Homo sapiens HeLa IC50 1000000.0 nM 10.1021/acs.jmedchem.0c01744
Homo sapiens HeLa Inhibition nan % 10.1016/j.bmc.2021.116041
Homo sapiens HeLa Inhibition nan % 10.1016/j.ejmech.2018.07.011
Homo sapiens HeLa MCC 100000.0 nM 10.1016/j.ejmech.2015.06.024
Homo sapiens Hep 3B2 Activity 0.4 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Hep 3B2 Activity 0.8 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Hep 3B2 Activity 1.5 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Hep 3B2 Activity 4.4 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Hep 3B2 Activity 17.4 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Hep 3B2 Activity 17.9 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Hep 3B2 Activity 63.9 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Hep 3B2 Activity 93.6 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Hep 3B2 Activity nan None 10.1021/acs.jnatprod.2c01155
Homo sapiens Hep 3B2 IC50 10000.0 nM 10.1021/acs.jmedchem.1c01036
Homo sapiens HepG2 Activity 0.0 % 10.1016/j.bmc.2011.06.025
Homo sapiens HepG2 Activity 11.9 % 10.1021/jm060736s
Homo sapiens HepG2 Activity 60.0 % 10.1016/j.bmcl.2015.04.014
Homo sapiens HepG2 Activity 60.0 % 10.1021/jm060736s
Homo sapiens HepG2 Activity 67.0 % 10.1016/j.bmcl.2015.04.014
Homo sapiens HepG2 Activity 67.7 % 10.1021/jm060736s
Homo sapiens HepG2 Activity 92.0 % 10.1016/j.bmcl.2015.04.014
Homo sapiens HepG2 Activity 93.0 % 10.1016/j.bmcl.2015.04.014
Homo sapiens HepG2 Activity 97.0 % 10.1016/j.bmcl.2015.04.014
Homo sapiens HepG2 Activity 16000000.0 RLU/mg 10.1021/jm060736s
Homo sapiens HepG2 Activity nan None 10.1021/acs.jmedchem.5b00511
Homo sapiens HepG2 Activity nan None 10.1021/acsmedchemlett.6b00466
Homo sapiens HepG2 Activity nan None 10.1021/ml3000808
Homo sapiens HepG2 CC50 1000.0 ug.mL-1 10.1016/j.bmcl.2015.04.014
Homo sapiens HepG2 CC50 1600.0 nM 10.1016/j.ejmech.2015.03.011
Homo sapiens HepG2 CC50 30000.0 nM 10.1016/j.bmcl.2011.06.113
Homo sapiens HepG2 CC50 30000.0 nM 10.1016/j.ejmech.2011.06.021
Homo sapiens HepG2 CC50 30000.0 nM 10.1016/j.ejmech.2012.04.029
Homo sapiens HepG2 CC50 30000.0 nM 10.1016/j.ejmech.2012.07.034
Homo sapiens HepG2 CC50 30000.0 nM 10.1016/j.ejmech.2014.05.037
Homo sapiens HepG2 CC50 30000.0 nM 10.1016/j.ejmech.2014.06.014
Homo sapiens HepG2 CC50 30000.0 nM 10.1016/j.ejmech.2014.07.113
Homo sapiens HepG2 CC50 30000.0 nM 10.1016/j.ejmech.2015.03.011
Homo sapiens HepG2 CC50 30000.0 nM 10.1016/j.ejmech.2016.04.059
Homo sapiens HepG2 CC50 30000.0 nM 10.1016/j.ejmech.2021.113722
Homo sapiens HepG2 CC50 30000.0 nM 10.1021/acs.jmedchem.0c02022
Homo sapiens HepG2 CC50 137420.0 nM 10.1016/j.ejmech.2018.08.063
Homo sapiens HepG2 CC50 393000.0 nM 10.1016/j.ejmech.2017.12.051
Homo sapiens HepG2 CC50 504100.0 nM 10.1016/j.ejmech.2012.12.010
Homo sapiens HepG2 CC50 810000.0 nM 10.1016/j.ejmech.2013.11.022
Homo sapiens HepG2 CC50 nan None 10.1016/j.bmcl.2017.12.060
Homo sapiens HepG2 CC50 nan None 10.1021/jm400246e
Homo sapiens HepG2 Drug uptake 12.0 mM 10.1021/jm060736s
Homo sapiens HepG2 Drug uptake 13.0 mM 10.1021/jm060736s
Homo sapiens HepG2 EC50 10100.0 nM 10.1016/j.ejmech.2018.05.022
Homo sapiens HepG2 EC50 10430.0 nM 10.1021/acs.jmedchem.0c00858
Homo sapiens HepG2 EC50 25000.0 nM 10.1016/j.bmcl.2014.09.061
Homo sapiens HepG2 EC50 25000.0 nM 10.1021/jm200636z
Homo sapiens HepG2 EC50 384000.0 nM 10.1021/acs.jmedchem.8b00143
Homo sapiens HepG2 EC50 nan None 10.1016/j.ejmech.2015.07.047
Homo sapiens HepG2 EC50 nan None 10.1021/jm500797g
Homo sapiens HepG2 GI50 22160.0 nM 10.1021/jm200463z
Homo sapiens HepG2 GI50 43090.0 nM 10.1016/j.bmc.2015.01.036
Homo sapiens HepG2 IC50 12.02 ug.mL-1 10.1021/jm501809x
Homo sapiens HepG2 IC50 8300.0 nM 10.1021/np100737q
Homo sapiens HepG2 IC50 10000.0 nM 10.1016/j.ejmech.2014.05.050
Homo sapiens HepG2 IC50 10000.0 nM 10.1021/acs.jmedchem.1c01036
Homo sapiens HepG2 IC50 12900.0 nM 10.1016/j.bmcl.2010.11.081
Homo sapiens HepG2 IC50 25000.0 nM 10.1021/acs.jmedchem.5b00511
Homo sapiens HepG2 IC50 30000.0 nM 10.1016/j.bmc.2009.05.022
Homo sapiens HepG2 IC50 30000.0 nM 10.1016/j.bmcl.2007.10.027
Homo sapiens HepG2 IC50 30000.0 nM 10.1016/j.ejmech.2009.11.005
Homo sapiens HepG2 IC50 37577.0 nM 10.1021/acs.jmedchem.0c00539
Homo sapiens HepG2 IC50 37577.0 nM 10.1021/acs.jmedchem.1c00748
Homo sapiens HepG2 IC50 37577.0 nM 10.1021/acs.jmedchem.8b01961
Homo sapiens HepG2 IC50 49020.0 nM 10.1016/j.ejmech.2021.113685
Homo sapiens HepG2 IC50 73700.0 nM 10.1021/acs.jmedchem.0c01744
Homo sapiens HepG2 IC50 116000.0 nM 10.1016/j.ejmech.2012.01.039
Homo sapiens HepG2 IC50 116000.0 nM 10.1021/jm201676t
Homo sapiens HepG2 IC50 384000.0 nM 10.1016/j.ejmech.2020.112941
Homo sapiens HepG2 IC50 nan None 10.1021/acs.jmedchem.7b00140
Homo sapiens HepG2 IC50 nan None 10.1039/C3MD00097D
Homo sapiens HepG2 IC50 nan None 10.1039/C7MD00052A
Homo sapiens HepG2 LD50 360.0 ug ml-1 10.1016/j.ejmech.2011.09.025
Homo sapiens HepG2 LD50 10000.0 nM 10.1021/jm500066b
Homo sapiens HepG2 Potency 562.3 nM None
Homo sapiens HepG2 TC50 4.3 uM 10.1021/jm300802s
Homo sapiens HepG2 TC50 31.0 uM 10.1021/jm300831b
Homo sapiens HERG AC50 7313.1 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 2500.0 nM 10.1016/j.bmcl.2004.06.070
Homo sapiens HERG IC50 2500.0 nM 10.1016/j.bmcl.2015.02.044
Homo sapiens HERG IC50 2500.0 nM 10.1021/jm8012618
Homo sapiens HERG IC50 2511.89 nM 10.1016/j.ejmech.2010.11.042
Homo sapiens HERG Inhibition 39.0 % 10.1021/acs.jmedchem.0c00539
Homo sapiens HERG Inhibition 39.0 % 10.1021/acs.jmedchem.8b01961
Homo sapiens HERG Inhibition 71.0 % 10.1021/jm501809x
Homo sapiens HERG Ki 3162.28 nM 10.1038/s41586-020-2286-9
Homo sapiens HERG Ki 7500.0 nM 10.1021/ml400015f
Homo sapiens Histamine H1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H3 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histone deacetylase IC50 nan None 10.1016/j.bmc.2009.10.042
Homo sapiens Histone deacetylase 6 Inhibition -43.27 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition -7.2 % 10.6019/CHEMBL4808148
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 IC50 nan None 10.1039/C7MD00052A
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Potency 25118.9 nM None
Homo sapiens HL-60 Activity 0.66 % 10.1016/j.bmc.2017.12.022
Homo sapiens HL-60 Activity 2.14 % 10.1016/j.bmc.2017.12.022
Homo sapiens HL-60 Activity 23.6 % 10.1016/j.bmc.2017.12.022
Homo sapiens HL-60 GI50 128000.0 nM 10.1016/j.bmc.2012.11.009
Homo sapiens HL-60 IC50 100000.0 nM 10.1016/j.bmc.2017.12.022
Homo sapiens HMEC-1 IC50 40000.0 nM 10.1021/acsmedchemlett.8b00592
Homo sapiens HMEC-1 IC50 100000.0 nM 10.1021/acs.jmedchem.6b01685
Homo sapiens Homo sapiens Activity 8.0 % 10.1128/aac.01111-08
Homo sapiens Homo sapiens Activity 14.0 % 10.1128/aac.01111-08
Homo sapiens Homo sapiens Activity 21.0 % 10.1128/aac.01111-08
Homo sapiens Homo sapiens Activity 24.0 % 10.1128/aac.01111-08
Homo sapiens Homo sapiens Activity 25.0 % 10.1128/aac.01111-08
Homo sapiens Homo sapiens Activity 33.0 % 10.1128/aac.01111-08
Homo sapiens Homo sapiens Activity 42.0 % 10.1128/aac.01111-08
Homo sapiens Homo sapiens Activity 64.0 % 10.1128/aac.01111-08
Homo sapiens Homo sapiens AUC 23876.0 ng.hr.mL-1 10.1128/aac.01269-09
Homo sapiens Homo sapiens AUC 31835.0 ng.hr.mL-1 10.1128/aac.01269-09
Homo sapiens Homo sapiens AUC 35659.0 ng.hr.mL-1 10.1128/aac.01269-09
Homo sapiens Homo sapiens AUC 37489.94 ng.hr.mL-1 10.1128/aac.00555-07
Homo sapiens Homo sapiens AUC 39185.3 ng.hr.mL-1 10.1128/aac.00555-07
Homo sapiens Homo sapiens AUC 39793.0 ng.hr.mL-1 10.1128/aac.01269-09
Homo sapiens Homo sapiens AUC 41255.0 ng.hr.mL-1 10.1128/aac.01269-09
Homo sapiens Homo sapiens AUC 47545.0 ng.hr.mL-1 10.1128/aac.01269-09
Homo sapiens Homo sapiens AUC 50028.0 ng.hr.mL-1 10.1128/aac.01269-09
Homo sapiens Homo sapiens AUC 59431.0 ng.hr.mL-1 10.1128/aac.01269-09
Homo sapiens Homo sapiens CL 1.8 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 4.1 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL 4.1 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL/F 2.167 mL.min-1.kg-1 10.1128/aac.00555-07
Homo sapiens Homo sapiens CL/F 3.6 L/hr 10.1128/aac.01269-09
Homo sapiens Homo sapiens CL/F 7.0 L/hr 10.1128/aac.01269-09
Homo sapiens Homo sapiens CL/F 9.2 L/hr 10.1128/aac.01269-09
Homo sapiens Homo sapiens CL/F 13.33 mL.min-1.kg-1 10.1128/aac.00555-07
Homo sapiens Homo sapiens CL/F 20.0 L/hr 10.1128/aac.01269-09
Homo sapiens Homo sapiens CL/F 29.3 L/hr 10.1128/aac.01269-09
Homo sapiens Homo sapiens CL/F 34.1 L/hr 10.1128/aac.01269-09
Homo sapiens Homo sapiens CL_renal 2.3 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL_renal 2.3 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens Cmax 240.0 nM 10.1128/aac.00527-07
Homo sapiens Homo sapiens Cmax 434.54 nM 10.1128/aac.01269-09
Homo sapiens Homo sapiens Cmax 578.34 nM 10.1128/aac.01269-09
Homo sapiens Homo sapiens Cmax 581.47 nM 10.1128/aac.01269-09
Homo sapiens Homo sapiens Cmax 725.27 nM 10.1128/aac.01269-09
Homo sapiens Homo sapiens Cmax 925.35 nM 10.1128/aac.01269-09
Homo sapiens Homo sapiens Cmax 1175.44 nM 10.1128/aac.01269-09
Homo sapiens Homo sapiens Cmax 1234.84 nM 10.1128/aac.01269-09
Homo sapiens Homo sapiens Cmax 1544.33 nM 10.1128/aac.01269-09
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 3.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens Fa 1.0 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fabs 89.0 % 10.1124/dmd.110.034629
Homo sapiens Homo sapiens F_fraction 0.8 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fg 0.87 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fh 0.92 None 10.1021/jm901371v
Homo sapiens Homo sapiens Hemolysis 1.0 % 10.1021/jm0305319
Homo sapiens Homo sapiens IC50 nan nM 10.1016/j.bmcl.2004.05.026
Homo sapiens Homo sapiens Inhibition nan % 10.1016/j.bmcl.2004.05.026
Homo sapiens Homo sapiens T1/2 0.16 hr 10.1128/aac.00555-07
Homo sapiens Homo sapiens T1/2 0.43 hr 10.1128/aac.00555-07
Homo sapiens Homo sapiens T1/2 12.8 hr 10.1128/aac.00555-07
Homo sapiens Homo sapiens T1/2 233.0 hr 10.1128/aac.00555-07
Homo sapiens Homo sapiens T1/2 240.0 hr 10.1128/aac.00527-07
Homo sapiens Homo sapiens T1/2 480.0 hr 10.1021/jm300802s
Homo sapiens Homo sapiens T1/2 730.0 hr 10.1016/j.ejmech.2009.02.024
Homo sapiens Homo sapiens TIME 12.0 hr 10.1128/aac.01111-08
Homo sapiens Homo sapiens TIME 26.4 hr 10.1128/aac.01111-08
Homo sapiens Homo sapiens TIME 33.6 hr 10.1128/aac.01111-08
Homo sapiens Homo sapiens Tlag 0.55 hr 10.1128/aac.00555-07
Homo sapiens Homo sapiens Tmax 6.6 hr 10.1128/aac.00527-07
Homo sapiens Homo sapiens Vc/F 39.9 l 10.1128/aac.01269-09
Homo sapiens Homo sapiens Vc/F 40.0 l 10.1128/aac.01269-09
Homo sapiens Homo sapiens Vc/F 4160.0 l 10.1128/aac.01269-09
Homo sapiens Homo sapiens Vc/F 4220.0 l 10.1128/aac.01269-09
Homo sapiens Homo sapiens Vd 100.0 L.kg-1 10.1128/aac.01111-08
Homo sapiens Homo sapiens Vd 200.0 L.kg-1 10.1021/jm300802s
Homo sapiens Homo sapiens Vd/F 154.0 L.kg-1 10.1128/aac.00555-07
Homo sapiens Homo sapiens Vdss 140.0 L.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens Vp/F 812.0 l 10.1128/aac.01269-09
Homo sapiens Homo sapiens Vp/F 840.0 l 10.1128/aac.01269-09
Homo sapiens Homo sapiens Vp/F 5190.0 l 10.1128/aac.01269-09
Homo sapiens Homo sapiens Vp/F 5200.0 l 10.1128/aac.01269-09
Homo sapiens HT-1080 ED50 6.5 ug ml-1 10.1021/np50091a005
Homo sapiens HT-29 IC50 58.0 ug.mL-1 10.1021/np9704157
Homo sapiens HT-29 IC50 3600.0 nM 10.1021/ml500348p
Homo sapiens Huh-7 Activity 1.9 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Huh-7 Activity 2.9 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Huh-7 Activity 3.4 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Huh-7 Activity 4.9 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Huh-7 Activity 12.1 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Huh-7 Activity 19.1 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Huh-7 Activity 65.4 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Huh-7 Activity 90.3 % 10.1021/acs.jnatprod.2c01155
Homo sapiens Huh-7 Activity nan None 10.1021/acs.jnatprod.2c01155
Homo sapiens Huh-7 CC50 100.0 ug.mL-1 10.1016/j.ejmech.2022.114774
Homo sapiens Huh-7 CC50 12420.0 nM 10.1073/pnas.0802982105
Homo sapiens Huh-7 CC50 50000.0 nM 10.1021/acs.jmedchem.0c00626
Homo sapiens Huh-7 Inhibition 2.0 % 10.1101/2020.04.13.039917
Homo sapiens Huh-7 Inhibition 3.0 % 10.1101/2020.04.13.039917
Homo sapiens HUVEC CC50 31500.0 nM 10.1016/j.bmcl.2021.128196
Homo sapiens Jurkat IC50 95000.0 nM 10.1016/j.bmc.2017.12.022
Homo sapiens Jurkat E6.1 Activity 1.4 % 10.1016/j.bmc.2017.12.022
Homo sapiens Jurkat E6.1 Activity 7.85 % 10.1016/j.bmc.2017.12.022
Homo sapiens Jurkat E6.1 Activity 23.7 % 10.1016/j.bmc.2017.12.022
Homo sapiens Jurkat E6.1 IC50 83640.0 nM 10.1016/j.bmc.2017.12.022
Homo sapiens K562 CC50 9700.0 nM 10.1021/jm8007322
Homo sapiens K562 CC50 25000.0 nM 10.1016/j.bmc.2010.08.001
Homo sapiens K562 IC50 43.8 ug.mL-1 10.1007/s00044-011-9694-1
Homo sapiens K562 IC50 25300.0 nM 10.1021/acs.jmedchem.0c00131
Homo sapiens K562 IC50 29030.0 nM 10.1016/j.bmc.2008.05.068
Homo sapiens K562 IC50 32000.0 nM 10.1016/j.bmc.2009.05.022
Homo sapiens K562 IC50 32000.0 nM 10.1016/j.ejmech.2009.11.005
Homo sapiens K562 IC50 nan None 10.1021/np960013j
Homo sapiens Kappa opioid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens KB CC50 44000.0 nM 10.1021/jm901300d
Homo sapiens KB CC50 187000.0 nM 10.1016/j.bmc.2007.05.038
Homo sapiens KB ED50 17.4 ug ml-1 10.1021/np010037c
Homo sapiens KB ED50 17.4 ug ml-1 10.1021/np050510c
Homo sapiens KB ED50 17.4 ug ml-1 10.1021/np50091a005
Homo sapiens KB ED50 30.8 uM 10.1021/np050313d
Homo sapiens KB ED50 260.0 uM 10.1021/jm7012375
Homo sapiens KB ED50 33700.0 nM 10.1021/np980144f
Homo sapiens KB GI 31.42 % 10.1016/j.bmcl.2011.05.119
Homo sapiens KB GI 96.95 % 10.1016/j.bmcl.2011.05.119
Homo sapiens KB IC50 17.4 ug.mL-1 10.1021/np50090a014
Homo sapiens KB IC50 17.4 ug.mL-1 10.1021/np9602325
Homo sapiens KB IC50 17.4 ug.mL-1 10.1021/np9605394
Homo sapiens KB IC50 51.4 ug.mL-1 10.1021/np010419i
Homo sapiens KB IC50 20400.0 nM 10.1021/np0101705
Homo sapiens KB IC50 22500.0 nM 10.1016/j.bmc.2009.10.005
Homo sapiens KB IC50 34000.0 nM 10.1021/ml4001084
Homo sapiens KB IC50 35950.0 nM 10.1016/j.bmcl.2011.05.119
Homo sapiens KB IC50 97480.0 nM 10.1016/j.bmcl.2008.08.043
Homo sapiens KB IC50 97725.5 nM 10.1016/j.bmc.2013.09.047
Homo sapiens KB IC50 110000.0 nM 10.1016/j.ejmech.2007.11.024
Homo sapiens KB IC50 nan None 10.1016/j.ejmech.2015.05.020
Homo sapiens KB IC50 nan None 10.1021/np960013j
Homo sapiens KB TC50 207.0 uM 10.1021/jm701247k
Homo sapiens KB TC50 nan None 10.1021/jm801352s
Homo sapiens KB TD50 127.33 uM 10.1021/jm7009292
Homo sapiens KYSE-410 Activity 11.3 % 10.1016/j.ejmech.2018.05.042
Homo sapiens KYSE-410 Activity 13.7 % 10.1016/j.ejmech.2018.05.042
Homo sapiens KYSE-410 Activity 20.7 % 10.1016/j.ejmech.2018.05.042
Homo sapiens KYSE-410 Activity 24.4 % 10.1016/j.ejmech.2018.05.042
Homo sapiens KYSE-410 Activity 64.3 % 10.1016/j.ejmech.2018.05.042
Homo sapiens KYSE-410 Activity 65.6 % 10.1016/j.ejmech.2018.05.042
Homo sapiens L02 IC50 15000.0 nM 10.1016/j.ejmech.2021.113685
Homo sapiens Liver microsome T1/2 1.0 hr 10.1021/jm501809x
Homo sapiens Liver microsomes Activity nan None 10.1021/tx300075j
Homo sapiens Liver microsomes Stability nan % 10.1021/tx300075j
Homo sapiens Liver microsomes T1/2 4.167 hr 10.1021/jm200149e
Homo sapiens Liver microsomes T1/2 12.48 hr 10.1021/jm100057h
Homo sapiens LNCaP Activity nan None 10.1021/acs.jmedchem.1c02113
Homo sapiens LNCaP Activity nan None 10.1021/acs.jmedchem.5b00511
Homo sapiens LNCaP ED50 14.3 ug ml-1 10.1021/np50091a005
Homo sapiens LNCaP IC50 32870.0 nM 10.1021/acs.jmedchem.5b00511
Homo sapiens Lymphocyte IC50 100000.0 nM 10.1016/j.bmc.2017.12.022
Homo sapiens Mahlavu IC50 10000.0 nM 10.1021/acs.jmedchem.1c01036
Homo sapiens MCF7 Activity 500.0 nM 10.1128/aac.00951-09
Homo sapiens MCF7 Activity nan None 10.1016/j.bmc.2021.116112
Homo sapiens MCF7 Activity nan None 10.1016/j.bmcl.2005.07.090
Homo sapiens MCF7 CC50 19000.0 nM 10.1039/C1MD00127B
Homo sapiens MCF7 CC50 19400.0 nM 10.1016/j.ejmech.2014.02.038
Homo sapiens MCF7 CC50 19400.0 nM 10.1016/j.ejmech.2014.03.059
Homo sapiens MCF7 CC50 19400.0 nM 10.1021/jm901300d
Homo sapiens MCF7 GI50 38440.0 nM 10.1016/j.bmc.2009.08.068
Homo sapiens MCF7 GI50 38440.0 nM 10.1016/j.bmc.2010.01.001
Homo sapiens MCF7 GI50 38440.0 nM 10.1016/j.ejmech.2010.05.046
Homo sapiens MCF7 GI50 64350.0 nM 10.1016/j.bmcl.2013.10.025
Homo sapiens MCF7 IC50 100.0 ug.mL-1 10.1021/np8005953
Homo sapiens MCF7 IC50 12000.0 nM 10.1021/np8000909
Homo sapiens MCF7 IC50 13200.0 nM 10.1016/j.ejmech.2022.114196
Homo sapiens MCF7 IC50 23430.0 nM 10.1021/acs.jmedchem.5b00511
Homo sapiens MCF7 IC50 36100.0 nM 10.1016/j.bmc.2009.10.013
Homo sapiens MCF7 IC50 38440.0 nM 10.1016/j.ejmech.2017.05.052
Homo sapiens MCF7 IC50 nan None 10.1016/j.bmc.2015.11.007
Homo sapiens MCF7 IC50 nan None 10.1016/j.ejmech.2010.03.006
Homo sapiens MCF7 Ratio nan None 10.1016/j.bmcl.2005.07.090
Homo sapiens MDA-MB-231 Activity nan None 10.1016/j.bmc.2021.116112
Homo sapiens MDA-MB-231 GI50 22520.0 nM 10.1016/j.bmc.2009.08.068
Homo sapiens MDA-MB-231 GI50 22520.0 nM 10.1016/j.ejmech.2010.05.046
Homo sapiens MDA-MB-231 IC50 22520.0 nM 10.1016/j.ejmech.2017.05.052
Homo sapiens MDA-MB-231 IC50 36530.0 nM 10.1016/j.bmc.2015.11.007
Homo sapiens MDA-MB-361 IC50 97000.0 nM 10.1021/acs.jmedchem.5b00511
Homo sapiens MDA-MB-468 GI50 28580.0 nM 10.1016/j.bmc.2009.08.068
Homo sapiens MDA-MB-468 GI50 28580.0 nM 10.1016/j.bmc.2010.01.001
Homo sapiens MDA-MB-468 IC50 10600.0 nM 10.1021/acs.jmedchem.0c00873
Homo sapiens MDA-MB-468 IC50 19860.0 nM 10.1016/j.bmc.2015.11.007
Homo sapiens MDA-MB-468 IC50 28580.0 nM 10.1016/j.ejmech.2017.05.052
Homo sapiens Melanocortin receptor 3 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 4 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens MIA PaCa-2 EC50 14000.0 nM 10.1021/acsmedchemlett.6b00392
Homo sapiens MIA PaCa-2 IC50 3500.0 nM 10.1016/j.ejmech.2018.08.028
Homo sapiens Monoamine oxidase A AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Motilin receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens MRC5 Activity 57000.0 nM 10.1021/acsmedchemlett.8b00222
Homo sapiens MRC5 Activity nan None 10.1016/j.bmcl.2006.11.051
Homo sapiens MRC5 CC50 50000.0 nM 10.1016/j.bmcl.2003.07.008
Homo sapiens MRC5 CC50 50000.0 nM 10.1016/j.bmcl.2004.06.056
Homo sapiens MRC5 CC50 50000.0 nM 10.1016/j.bmcl.2005.09.058
Homo sapiens MRC5 CC50 50000.0 nM 10.1016/j.ejmech.2007.11.003
Homo sapiens MRC5 CC50 50000.0 nM 10.1021/jm020960r
Homo sapiens MRC5 CC50 50000.0 nM 10.1021/jm0602763
Homo sapiens MRC5 CC50 nan None 10.1021/acs.jnatprod.7b00249
Homo sapiens MRC5 Cytotoxicity 0.0 % 10.1021/jm010842o
Homo sapiens MRC5 IC50 64.0 nM 10.1021/jm9018383
Homo sapiens MRC5 IC50 50000.0 nM 10.1016/j.bmc.2008.09.038
Homo sapiens MRC5 IC50 50000.0 nM 10.1016/s0960-894x(02)00475-4
Homo sapiens MRC5 IC50 58200.0 nM 10.1021/acs.jnatprod.1c00870
Homo sapiens MRC5 IC50 nan nM 10.1016/j.bmcl.2004.05.026
Homo sapiens MRC5 Selectivity index 12.5 None 10.1021/jm0602763
Homo sapiens MRC5 Selectivity index 397.0 None 10.1016/j.bmcl.2003.07.008
Homo sapiens MRC5 SI 396.0 None 10.1016/j.bmcl.2004.06.056
Homo sapiens Multidrug resistance-associated protein 4 IC50 103900.0 nM 10.1093/toxsci/kft176
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 Ki 9120.11 nM 10.1038/s41586-020-2286-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 Ki 4677.35 nM 10.1038/s41586-020-2286-9
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 Ki 3311.31 nM 10.1038/s41586-020-2286-9
Homo sapiens Muscarinic acetylcholine receptor M4 Ki 5754.4 nM 10.1038/s41586-020-2286-9
Homo sapiens Muscarinic acetylcholine receptor M5 Ki 21877.62 nM 10.1038/s41586-020-2286-9
Homo sapiens MV4-11 Inhibition nan % 10.1021/acs.jmedchem.0c00442
Homo sapiens NADH-cytochrome b5 reductase Activity 0.067 nM min-1 (mg of protein)-1 10.1016/s0960-894x(99)00058-x
Homo sapiens NADH-cytochrome b5 reductase Methemoglobin 0.065 None 10.1016/S0960-894X(97)10074-9
Homo sapiens NCH89 IC50 41200.0 nM 10.1021/jm9018383
Homo sapiens NCI-H460 Activity nan None 10.1021/ml500348p
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens NFF IC50 34000.0 nM 10.1016/j.bmc.2011.12.037
Homo sapiens NFF IC50 37300.0 nM 10.1016/j.bmc.2012.09.052
Homo sapiens NFF IC50 45900.0 nM 10.1021/ml400447v
Homo sapiens NFF IC50 46608.0 nM 10.1016/j.ejmech.2018.09.018
Homo sapiens NFF IC50 1000000.0 nM 10.1016/j.bmcl.2013.09.015
Homo sapiens NFF Inhibition nan % 10.1016/j.bmc.2011.07.009
Homo sapiens Norepinephrine transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Nuclear receptor subfamily 4 group A member 1 Activity nan None 10.1021/acs.jmedchem.0c00894
Homo sapiens Nuclear receptor subfamily 4 group A member 2 Activity nan None 10.1021/acs.jmedchem.0c00894
Homo sapiens Nuclear receptor subfamily 4 group A member 2 Activity nan None 10.1021/acs.jmedchem.0c01779
Homo sapiens Nuclear receptor subfamily 4 group A member 2 EC50 47000.0 nM 10.1021/acs.jmedchem.0c01779
Homo sapiens Nuclear receptor subfamily 4 group A member 2 EC50 50000.0 nM 10.1021/acs.jmedchem.2c00585
Homo sapiens Nuclear receptor subfamily 4 group A member 2 FC 2.0 None 10.1021/acs.jmedchem.0c01779
Homo sapiens Nuclear receptor subfamily 4 group A member 3 Activity nan None 10.1021/acs.jmedchem.0c00894
Homo sapiens PANC-1 FC 2.0 None 10.1021/acs.jnatprod.8b00733
Homo sapiens PBMC IC50 5100.0 nM 10.1016/j.ejmech.2007.11.012
Homo sapiens P-glycoprotein 1 Activity nan None None
Homo sapiens P-glycoprotein 1 % maximum response 2.49 % None
Homo sapiens P-glycoprotein 1 Papp 44.9 nm/s None
Homo sapiens P-glycoprotein 1 Papp 172.0 nm/s None
Homo sapiens P-glycoprotein 1 Ratio_ATPase activity 0.77 None None
Homo sapiens P-glycoprotein 1 Ratio_Papp 3.83 None None
Homo sapiens Phosphodiesterase 3A AC50 17999.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Plasma PPB 50.0 % 10.1128/aac.01111-08
Homo sapiens Plasma PPB 87.0 % 10.1021/jm200265b
Homo sapiens Plasma T1/2 1.0 hr 10.1016/j.bmc.2013.09.065
Homo sapiens Pregnane X receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Prion protein EC50 4000.0 nM 10.1021/jm034093h
Homo sapiens Progesterone receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Quinone reductase 2 IC50 1500.0 nM 10.1016/j.bmcl.2010.10.070
Homo sapiens Quinone reductase 2 Inhibition nan % 10.1016/j.bmcl.2010.10.070
Homo sapiens Raji EC50 25000.0 nM 10.1016/j.bmcl.2014.09.061
Homo sapiens SCC-4 Activity nan None 10.1016/j.ejmech.2022.114274
Homo sapiens Serine/threonine-protein kinase mTOR IC50 270.0 nM 10.1016/j.ejmech.2020.112391
Homo sapiens Serine/threonine-protein kinase mTOR IC50 270.0 nM 10.1021/acs.jmedchem.0c01511
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None 10.1021/ml300008j
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serum albumin Ka 2.0 10^3/M 10.1016/j.bmc.2008.01.053
Homo sapiens SH-SY5Y CC50 30000.0 nM 10.1016/j.bmc.2018.03.016
Homo sapiens SH-SY5Y Potency 15848.9 nM None
Homo sapiens Sigma intracellular receptor 2 Ki 501.19 nM 10.1038/s41586-020-2286-9
Homo sapiens Sigma opioid receptor Ki 79.43 nM 10.1038/s41586-020-2286-9
Homo sapiens SK-MEL IC50 nan None 10.1016/j.ejmech.2015.05.020
Homo sapiens SK-MEL-2 ED50 20.0 ug ml-1 10.1021/np50091a005
Homo sapiens SK-N-BE(2) Activity nan None 10.1021/acs.jmedchem.0c00894
Homo sapiens SK-OV-3 IC50 nan None 10.1016/j.ejmech.2015.05.020
Homo sapiens SK-OV-3 IC50 nan None 10.1021/np960013j
Homo sapiens Solute carrier family 22 member 1 Inhibition 46.0 % 10.1021/jm8003152
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition -1.4 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition -7.2 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 2B1 Inhibition 23.5 % 10.1021/jm300212s
Homo sapiens SW480 IC50 14700.0 nM 10.1016/j.ejmech.2022.114196
Homo sapiens THP-1 Activity 500.0 nM 10.1128/aac.00951-09
Homo sapiens THP-1 IC50 40000.0 nM 10.1016/j.bmc.2010.06.067
Homo sapiens THP-1 IC50 40000.0 nM 10.1016/j.bmcl.2007.10.027
Homo sapiens THP-1 IC50 40000.0 nM 10.1016/j.bmcl.2009.08.013
Homo sapiens THP-1 IC50 40000.0 nM 10.1016/j.ejmech.2009.10.022
Homo sapiens THP-1 LC50 250000.0 nM 10.1016/j.bmcl.2007.10.027
Homo sapiens Thromboxane A2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens TLR7 and TLR8 Inhibition nan % 10.1128/aac.01246-09
Homo sapiens Toll-like receptor 7 Inhibition nan % 10.1021/jm2010207
Homo sapiens Toll-like receptor 7 Inhibition nan % 10.1128/aac.01246-09
Homo sapiens Toll-like receptor 9 Inhibition nan % 10.1128/aac.01246-09
Homo sapiens Toll-like receptor (TLR7/TLR9) Activity 4.3 % 10.1128/aac.01246-09
Homo sapiens Toll-like receptor (TLR7/TLR9) Activity 8.2 % 10.1128/aac.01246-09
Homo sapiens Toll-like receptor (TLR7/TLR9) Activity 11.1 % 10.1128/aac.01246-09
Homo sapiens Toll-like receptor (TLR7/TLR9) Activity 12.6 % 10.1128/aac.01246-09
Homo sapiens Toll-like receptor (TLR7/TLR9) Inhibition 23.4 % 10.1128/aac.01246-09
Homo sapiens Toll-like receptor (TLR7/TLR9) Inhibition nan % 10.1128/aac.01246-09
Homo sapiens Type-1 angiotensin II receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 707.9 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 794.3 nM None
Homo sapiens Vasopressin V1a receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens ZR-75-1 ED50 1.2 ug ml-1 10.1021/np50091a005
Human alphaherpesvirus 1 Human alphaherpesvirus 1 EC50 20000.0 nM 10.1016/j.ejmech.2015.06.024
Human alphaherpesvirus 1 Human alphaherpesvirus 1 IC50 27.0 ug.mL-1 10.1021/jm00402a016
Human alphaherpesvirus 1 Human alphaherpesvirus 1 IC50 85.0 ug.mL-1 10.1021/jm00402a016
Human alphaherpesvirus 1 Human alphaherpesvirus 1 Therapeutic index 3.0 None 10.1021/jm00402a016
Human alphaherpesvirus 2 Human alphaherpesvirus 2 EC50 20000.0 nM 10.1016/j.ejmech.2015.06.024
Human alphaherpesvirus 3 Human alphaherpesvirus 3 EC50 4000.0 nM 10.1016/j.ejmech.2015.06.024
Human betaherpesvirus 5 Human betaherpesvirus 5 EC50 4000.0 nM 10.1016/j.ejmech.2015.06.024
Human betaherpesvirus 5 Human betaherpesvirus 5 EC50 20000.0 nM 10.1016/j.ejmech.2015.06.024
Human coronavirus 229E Human coronavirus 229E EC50 1300.0 nM 10.1021/acsmedchemlett.2c00123
Human coronavirus 229E Human coronavirus 229E EC50 3300.0 nM 10.1016/j.ejmech.2020.112275
Human coronavirus 229E Human coronavirus 229E EC50 3300.0 nM 10.1021/acs.jmedchem.0c00626
Human coronavirus OC43 Human coronavirus OC43 EC50 330.0 nM 10.1021/acs.jmedchem.0c00626
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 nan None 10.1021/acs.jnatprod.5b00073
Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50 12480.0 nM 10.1016/j.bmc.2012.06.038
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 integrase IC50 4073802778041.12 nM 10.1007/s00044-011-9593-5
Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 nan None 10.1021/acs.jnatprod.5b00073
Human orthopneumovirus Human orthopneumovirus EC50 100000.0 nM 10.1016/j.ejmech.2015.06.024
Human respirovirus 3 Human respirovirus 3 EC50 100000.0 nM 10.1016/j.ejmech.2015.06.024
Influenza A virus Influenza A virus Activity nan None 10.1016/j.ejmech.2020.112223
Influenza A virus Influenza A virus EC50 20000.0 nM 10.1016/j.ejmech.2015.06.024
Influenza A virus Influenza A virus Inhibition nan % 10.1016/j.ejmech.2018.08.058
Influenza B virus Influenza B virus EC50 20000.0 nM 10.1016/j.ejmech.2015.06.024
Klebsiella pneumoniae Klebsiella pneumoniae MIC 20000.0 nM 10.6019/CHEMBL4513161
Lacticaseibacillus casei Lacticaseibacillus casei IC50 6000000.0 nM 10.1021/jm00212a010
Lacticaseibacillus casei Lacticaseibacillus casei IC50 6400000.0 nM 10.1021/jm00212a010
Lacticaseibacillus casei Lacticaseibacillus casei Inhibition nan % 10.1021/jm00212a010
Lacticaseibacillus casei Lacticaseibacillus casei Ratio IC50 1.0 None 10.1021/jm00212a010
Leishmania amazonensis Leishmania amazonensis Activity nan None 10.1016/j.bmcl.2005.07.090
Leishmania amazonensis Leishmania amazonensis IC50 20000.0 nM 10.1016/j.bmcl.2011.05.125
Leishmania amazonensis Leishmania amazonensis IC50 nan nM 10.1016/j.bmcl.2004.05.026
Leishmania amazonensis Leishmania amazonensis IC50 nan None 10.1016/j.ejmech.2014.06.022
Leishmania amazonensis Leishmania amazonensis Ratio IC50 100.0 None 10.1016/j.bmcl.2011.05.125
Leishmania braziliensis Leishmania braziliensis IC50 nan None 10.1016/j.bmc.2014.11.028
Leishmania donovani Leishmania donovani EC50 nan None 10.1021/np2004825
Leishmania donovani Leishmania donovani IC50 0.055 ug.mL-1 10.1016/j.ejmech.2007.03.003
Leishmania donovani Leishmania donovani IC50 30000.0 nM 10.1128/aac.00425-07
Leishmania donovani Leishmania donovani IC50 58850.0 nM 10.6019/CHEMBL3392926
Leishmania donovani Leishmania donovani IC50 196150.0 nM 10.6019/CHEMBL3392926
Leishmania donovani Leishmania donovani IC50 nan None 10.1007/s00044-011-9798-7
Leishmania donovani Leishmania donovani IC50 nan None 10.1016/j.bmc.2006.10.006
Leishmania donovani Leishmania donovani IC50 nan None 10.1016/j.bmc.2009.10.042
Leishmania donovani Leishmania donovani IC50 nan None 10.1016/j.bmcl.2008.11.098
Leishmania donovani Leishmania donovani IC50 nan None 10.1021/jm100507q
Leishmania donovani Leishmania donovani IC50 nan None 10.1021/np010419i
Leishmania donovani Leishmania donovani IC50 nan None 10.1021/np020592u
Leishmania donovani Leishmania donovani IC50 nan None 10.1021/np030045o
Leishmania donovani Leishmania donovani IC50 nan None 10.1021/np030086k
Leishmania donovani Leishmania donovani IC50 nan None 10.1021/np030524n
Leishmania donovani Leishmania donovani IC50 nan None 10.1021/np0400095
Leishmania donovani Leishmania donovani IC50 nan None 10.1021/np0601399
Leishmania donovani Leishmania donovani IC50 nan None 10.1021/np300638f
Leishmania donovani Leishmania donovani IC50 nan None 10.1021/np800163u
Leishmania donovani Leishmania donovani IC50 nan None 10.1021/np800653z
Leishmania donovani Leishmania donovani IC50 nan None 10.1039/C3MD00097D
Leishmania donovani Leishmania donovani IC90 nan None 10.1016/j.bmc.2006.10.006
Leishmania donovani Leishmania donovani IC90 nan None 10.1016/j.bmc.2009.10.042
Leishmania donovani Leishmania donovani IC90 nan None 10.1021/jm100507q
Leishmania donovani Leishmania donovani IC90 nan None 10.1021/np020592u
Leishmania donovani Leishmania donovani IC90 nan None 10.1021/np030045o
Leishmania donovani Leishmania donovani IC90 nan None 10.1021/np030086k
Leishmania donovani Leishmania donovani IC90 nan None 10.1021/np030524n
Leishmania donovani Leishmania donovani IC90 nan None 10.1021/np0400095
Leishmania donovani Leishmania donovani IC90 nan None 10.1021/np0601399
Leishmania donovani Leishmania donovani IC90 nan None 10.1021/np800163u
Leishmania donovani Leishmania donovani IC90 nan None 10.1021/np800653z
Leishmania donovani Leishmania donovani IC90 nan None 10.1039/C3MD00097D
Leishmania infantum Leishmania infantum GI50 3700.0 nM 10.1016/j.bmc.2012.11.009
Leishmania infantum Leishmania infantum IC50 24100.0 nM 10.1128/aac.00587-08
Leishmania infantum Leishmania infantum IC50 nan nM 10.1016/j.bmcl.2004.05.026
Leishmania infantum Leishmania infantum IC50 nan None 10.1016/j.bmc.2014.11.028
Leishmania infantum Leishmania infantum IC50 nan None 10.1016/j.bmcl.2017.02.049
Leishmania infantum Leishmania infantum IC50 nan None 10.1021/acsmedchemlett.1c00354
Leishmania infantum Leishmania infantum IC50 nan None 10.1128/aac.00587-08
Leishmania major Leishmania major EC50 18750.0 nM 10.1128/aac.01545-10
Leishmania major Leishmania major EC50 23820.0 nM 10.1128/aac.01545-10
Leishmania major Leishmania major Ratio EC50 1.3 None 10.1128/aac.01545-10
Leishmania mexicana Leishmania mexicana IC50 50000.0 nM 10.1016/j.bmc.2010.07.008
Leishmania tropica Leishmania tropica IC50 nan None 10.1016/j.bmc.2014.11.028
Leishmania tropica Leishmania tropica IC50 nan None 10.1021/acsmedchemlett.1c00354
Macaca mulatta Rhesus monkey Activity nan None 10.1021/jm8012618
Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 100000.0 nM 10.1016/j.ejmech.2015.06.024
Mesocricetus auratus BHK-21 CC50 20000.0 nM 10.1021/acs.jmedchem.0c00626
Middle East respiratory syndrome-related coronavirus Middle East respiratory syndrome-related coronavirus EC50 3000.0 nM 10.1016/j.ejmech.2020.112275
Mus musculus FM3A EC50 0.00032 nM 10.1021/jm0201971
Mus musculus FM3A EC50 32000.0 nM 10.1016/j.bmc.2008.04.051
Mus musculus FM3A EC50 32000.0 nM 10.1016/j.bmcl.2006.02.030
Mus musculus FM3A EC50 32000.0 nM 10.1021/jm000952f
Mus musculus FM3A EC50 32000.0 nM 10.1021/jm010448q
Mus musculus FM3A EC50 32000.0 nM 10.1021/jm0155704
Mus musculus FM3A EC50 32000.0 nM 10.1021/jm0302086
Mus musculus FM3A EC50 32000.0 nM 10.1021/jm990131e
Mus musculus FM3A Ratio EC50 1800.0 None 10.1016/j.bmcl.2006.02.030
Mus musculus FM3A Selectivity 1778.0 None 10.1021/jm010448q
Mus musculus FM3A Toxicity ratio 1800.0 None 10.1021/jm0155704
Mus musculus J774 Activity 0.0 % 10.1016/j.bmc.2011.06.025
Mus musculus J774 EC50 47200.0 nM 10.1021/acs.jmedchem.6b00759
Mus musculus J774 EC50 47200.0 nM 10.1021/acs.jmedchem.7b00738
Mus musculus J774 EC50 nan None 10.1021/jm1007903
Mus musculus J774 IC50 nan None 10.1021/jm061232x
Mus musculus L1210 IC50 15000.0 nM 10.1016/j.ejmech.2015.06.024
Mus musculus L929 EC50 18.6 ug.mL-1 10.1021/jm0601809
Mus musculus L929 IC50 14.0 ug.mL-1 10.1021/np8004612
Mus musculus L929 Ratio EC50 392.0 None 10.1021/jm0601809
Mus musculus Liver T1/2 1.0 hr 10.1021/jm501809x
Mus musculus Liver T1/2 2.95 hr 10.1021/jm200149e
Mus musculus Monoamine oxidase A Activity nan None 10.1021/jm800656v
Mus musculus Mus musculus Activity 0.0 % 10.1128/aac.01526-09
Mus musculus Mus musculus Activity 1.4 % 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 1.5 % 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 2.0 % 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 2.1 % 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 2.3 % 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 2.4 % 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 2.7 % 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 4.0 None 10.1016/s0960-894x(03)00782-0
Mus musculus Mus musculus Activity 6.2 % 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 12.8 day 10.1021/jm050966r
Mus musculus Mus musculus Activity 15.1 cm 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 18.7 cm/s 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 22.7 day 10.1021/jm0606241
Mus musculus Mus musculus Activity 25.6 day 10.1021/jm050966r
Mus musculus Mus musculus Activity 35.0 % 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 45.8 cm 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 300.0 mg kg-1 10.1021/jm8012757
Mus musculus Mus musculus Activity 416.4 cm 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity 840.0 mg kg-1 10.1021/jm8012757
Mus musculus Mus musculus Activity nan None 10.1016/j.bmcl.2006.08.009
Mus musculus Mus musculus Activity nan None 10.1016/j.bmcl.2015.04.014
Mus musculus Mus musculus Activity nan None 10.1016/j.ejmech.2007.11.003
Mus musculus Mus musculus Activity nan None 10.1016/j.ejmech.2013.06.002
Mus musculus Mus musculus Activity nan None 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Activity nan None 10.1021/jm070733v
Mus musculus Mus musculus Activity nan None 10.1021/jm7012375
Mus musculus Mus musculus Activity nan None 10.1021/jm8012757
Mus musculus Mus musculus Activity nan None 10.1021/ml3000808
Mus musculus Mus musculus Activity nan None 10.1021/np060233p
Mus musculus Mus musculus Activity nan None 10.1128/aac.01304-08
Mus musculus Mus musculus AUC 844.16 ng.hr.mL-1 10.1021/jm100057h
Mus musculus Mus musculus CL 17.0 mL.min-1.kg-1 10.1021/ml4002858
Mus musculus Mus musculus Cmax 444.3 nM 10.1021/jm100057h
Mus musculus Mus musculus Complete survival dose 256.0 mg kg-1 10.1021/jm010089z
Mus musculus Mus musculus ED50 1.0 mg.kg-1 10.1021/jm0102396
Mus musculus Mus musculus ED50 1.0 mg kg-1 5day-1 10.1021/jm020584a
Mus musculus Mus musculus ED50 1.1 mg.kg-1 10.1021/jm0492608
Mus musculus Mus musculus ED50 1.7 (mg/kg)/day 10.1021/jm049040u
Mus musculus Mus musculus ED50 1.8 mg.kg-1 10.1021/jm980529v
Mus musculus Mus musculus ED50 1.9 mg kg-1 5day-1 10.1021/jm020584a
Mus musculus Mus musculus ED50 1.9 (mg/kg)/day 10.1021/jm049040u
Mus musculus Mus musculus ED50 2.0 mg.kg-1 10.1021/jm0201971
Mus musculus Mus musculus ED50 2.4 mg kg-1 5day-1 10.1021/jm020584a
Mus musculus Mus musculus ED50 3.0 (mg/kg)/day 10.1021/jm049040u
Mus musculus Mus musculus ED50 4.7 umol.kg-1 10.1021/jm990131e
Mus musculus Mus musculus ED50 5.0 mg.kg-1 10.1021/jm0102396
Mus musculus Mus musculus ED90 1.2 mg kg-1 5day-1 10.1021/jm020584a
Mus musculus Mus musculus ED90 2.3 mg kg-1 5day-1 10.1021/jm020584a
Mus musculus Mus musculus ED90 3.0 mg kg-1 10.1021/jm010089z
Mus musculus Mus musculus ED90 3.1 mg kg-1 10.1021/jm980529v
Mus musculus Mus musculus ED90 3.1 (mg/kg)/day 10.1021/jm049040u
Mus musculus Mus musculus ED90 3.3 mg kg-1 10.1021/jm0201971
Mus musculus Mus musculus ED90 4.2 (mg/kg)/day 10.1021/jm049040u
Mus musculus Mus musculus ED90 9.4 uM kg-1 10.1021/jm990131e
Mus musculus Mus musculus ED90 56.0 mg kg-1 5day-1 10.1021/jm020584a
Mus musculus Mus musculus ILS 15.0 % 10.1021/jm0201971
Mus musculus Mus musculus Infected erythrocytes 62.1 % 10.1021/jm020244p
Mus musculus Mus musculus Infected erythrocytes 65.0 % 10.1021/jm020244p
Mus musculus Mus musculus Infected erythrocytes 71.3 % 10.1021/jm020244p
Mus musculus Mus musculus Infected erythrocytes 81.3 % 10.1021/jm020244p
Mus musculus Mus musculus Infected erythrocytes 82.4 % 10.1021/jm020244p
Mus musculus Mus musculus Inhibition 0.0 % 10.1021/np8000909
Mus musculus Mus musculus Inhibition 5.15 % 10.1021/jm058208o
Mus musculus Mus musculus Inhibition 100.0 % 10.1021/np8000909
Mus musculus Mus musculus LD50 70.0 mg.kg-1 10.1016/j.bmcl.2007.09.044
Mus musculus Mus musculus LD50 nan None 10.1021/jm0601809
Mus musculus Mus musculus Mean survival days 22.7 day 10.1021/jm070201e
Mus musculus Mus musculus MSD 20.0 day 10.1016/j.bmc.2010.07.046
Mus musculus Mus musculus MST 14.8 day 10.1016/j.bmcl.2003.10.051
Mus musculus Mus musculus MST 17.6 day 10.1016/j.bmcl.2003.10.051
Mus musculus Mus musculus MST 17.6 None 10.1016/s0960-894x(03)00782-0
Mus musculus Mus musculus MST 20.0 day 10.1021/jm061002i
Mus musculus Mus musculus MST 20.0 None 10.1016/s0960-894x(03)00782-0
Mus musculus Mus musculus MTD 240.0 mg kg-1 10.1016/j.bmc.2009.05.011
Mus musculus Mus musculus No. of mice protected 3.0 None 10.1016/s0960-894x(02)00320-7
Mus musculus Mus musculus Number 1.0 None 10.1021/jm9803828
Mus musculus Mus musculus Number 2.0 None 10.1021/jm9803828
Mus musculus Mus musculus Number 3.0 None 10.1021/jm9803828
Mus musculus Mus musculus Parasitemia 0.0 % 10.1021/jm970401y
Mus musculus Mus musculus Parasitemia 0.59 % 10.1021/jm970401y
Mus musculus Mus musculus Parasitemia 1.53 % 10.1016/s0960-894x(02)00320-7
Mus musculus Mus musculus Parasitemia 2.08 % 10.1021/jm970401y
Mus musculus Mus musculus Parasitemia 17.6 % 10.1016/s0960-894x(02)00320-7
Mus musculus Mus musculus Parasitemia 32.74 % 10.1016/s0960-894x(02)00320-7
Mus musculus Mus musculus Parasitemia 60.1 % 10.1021/jm970401y
Mus musculus Mus musculus Parasitemia 64.7 % 10.1021/jm970401y
Mus musculus Mus musculus Parasitemia 69.2 % 10.1021/jm970401y
Mus musculus Mus musculus Parasitemia 76.6 % 10.1021/jm970401y
Mus musculus Mus musculus Reduction 100.0 % 10.1021/jm030084x
Mus musculus Mus musculus Suppression 100.0 % 10.1016/j.bmcl.2003.10.051
Mus musculus Mus musculus Suppression 100.0 % 10.1016/s0960-894x(03)00782-0
Mus musculus Mus musculus Survival 0.0 None 10.1021/jm020244p
Mus musculus Mus musculus Survival 4.0 % 10.1021/jm010089z
Mus musculus Mus musculus Survival 100.0 % 10.1016/j.bmc.2007.02.027
Mus musculus Mus musculus Survival rate 0.0 % 10.1021/jm020244p
Mus musculus Mus musculus Survival time 15.0 day 10.1016/j.bmcl.2004.10.037
Mus musculus Mus musculus T1/2 5.5 hr 10.1021/jm100057h
Mus musculus Mus musculus T/C 41 1.71 None 10.1021/jm0101747
Mus musculus Mus musculus T/C untreated 1.81 None 10.1021/jm0101747
Mus musculus Mus musculus TIME 0.0005833 hr 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus TIME 0.004194 hr 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus TIME 0.006722 hr 10.1021/acs.jmedchem.7b01417
Mus musculus Mus musculus Tmax 0.5 hr 10.1021/jm100057h
Mus musculus NIH3T3 IC50 50000.0 nM 10.1016/j.ejmech.2013.08.037
Mus musculus NIH3T3 IC50 71954.0 nM 10.1016/j.bmc.2011.10.037
Mus musculus NIH3T3 TC50 80.0 uM 10.1021/jm300802s
Mus musculus NIH3T3 TC50 80.0 uM 10.1021/jm300831b
Mus musculus NSO TC50 14.9 uM 10.1021/jm801352s
Mus musculus NSO TC50 nan None 10.1021/jm701247k
Mus musculus P388 ED50 5.0 ug ml-1 10.1021/np50091a005
Mus musculus Peritoneal macrophage LD50 134.5 uM 10.1016/j.ejmech.2017.10.051
Mus musculus Plasma IC50 3.95 ug.mL-1 10.1016/j.ejmech.2013.05.023
Mus musculus Plasma Inhibition nan % 10.1016/j.ejmech.2013.05.023
Mus musculus Plasma T1/2 1.0 hr 10.1016/j.bmc.2013.09.065
Mus musculus ScN2a Activity 10000.0 nM 10.1021/jm0602763
Mus musculus ScN2a Activity nan None 10.1021/jm0602763
Mus musculus ScN2a EC50 4000.0 nM 10.1021/jm0602763
Mus musculus ScN2a Selectivity index 2.5 None 10.1021/jm0602763
Mus musculus WEHI ED50 9.7 uM 10.1016/j.bmcl.2006.07.060
Mycobacterium intracellulare Mycobacterium intracellulare Activity nan None 10.1016/j.bmc.2006.10.006
Mycobacterium tuberculosis Mycobacterium tuberculosis IC50 8.0 ug.mL-1 10.1016/j.bmc.2010.07.008
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC nan None 10.1021/np020592u
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC nan None 10.1021/np0400095
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC nan None 10.1021/np0601399
Mycobacterium tuberculosis Mycobacterium tuberculosis MIC99 160.0 uM 10.1021/ml300362a
Oryzias latipes Oryzias latipes LD50 121.0 uM 10.1021/np0601399
Plasmodium berghei Plasmodium berghei Activity 0.0 % 10.1016/j.bmcl.2009.11.088
Plasmodium berghei Plasmodium berghei Activity 0.0 % 10.1021/jm900672t
Plasmodium berghei Plasmodium berghei Activity 0.0 % 10.1021/jm901473s
Plasmodium berghei Plasmodium berghei Activity 0.0 % 10.1128/aac.01526-09
Plasmodium berghei Plasmodium berghei Activity 0.1 % 10.1021/jm7009292
Plasmodium berghei Plasmodium berghei Activity 0.1 % 10.1021/np010216u
Plasmodium berghei Plasmodium berghei Activity 0.13 % 10.1021/jm7009292
Plasmodium berghei Plasmodium berghei Activity 0.2 % 10.1016/j.bmc.2019.01.016
Plasmodium berghei Plasmodium berghei Activity 0.2 % 10.1021/jm900672t
Plasmodium berghei Plasmodium berghei Activity 0.32 % 10.1016/j.ejmech.2021.113865
Plasmodium berghei Plasmodium berghei Activity 0.6 % 10.1016/j.bmc.2015.05.040
Plasmodium berghei Plasmodium berghei Activity 0.6 % 10.1016/j.bmc.2019.01.016
Plasmodium berghei Plasmodium berghei Activity 0.6 % 10.1016/j.ejmech.2017.10.051
Plasmodium berghei Plasmodium berghei Activity 0.8 % 10.1016/j.bmc.2017.12.022
Plasmodium berghei Plasmodium berghei Activity 1.0 % 10.1016/j.bmc.2007.02.027
Plasmodium berghei Plasmodium berghei Activity 1.3 % 10.1016/j.ejmech.2008.08.005
Plasmodium berghei Plasmodium berghei Activity 1.31 % 10.1016/j.bmc.2008.02.011
Plasmodium berghei Plasmodium berghei Activity 1.55 % 10.1016/j.bmcl.2015.04.014
Plasmodium berghei Plasmodium berghei Activity 1.72 % 10.1016/j.bmcl.2015.04.014
Plasmodium berghei Plasmodium berghei Activity 2.2 % 10.1021/np9605246
Plasmodium berghei Plasmodium berghei Activity 3.0 % 10.1016/j.ejmech.2008.09.044
Plasmodium berghei Plasmodium berghei Activity 3.66 % 10.1016/j.ejmech.2007.01.001
Plasmodium berghei Plasmodium berghei Activity 4.0 % 10.1021/jm900672t
Plasmodium berghei Plasmodium berghei Activity 5.99 % 10.1016/j.bmcl.2019.02.029
Plasmodium berghei Plasmodium berghei Activity 6.2 % 10.1128/aac.00562-08
Plasmodium berghei Plasmodium berghei Activity 8.0 % 10.1021/jm900672t
Plasmodium berghei Plasmodium berghei Activity 8.5 % 10.1016/j.bmc.2007.02.027
Plasmodium berghei Plasmodium berghei Activity 10.76 % 10.1016/j.bmcl.2019.02.029
Plasmodium berghei Plasmodium berghei Activity 11.9 % 10.1016/j.bmc.2019.01.016
Plasmodium berghei Plasmodium berghei Activity 30.0 % 10.1016/j.ejmech.2008.08.005
Plasmodium berghei Plasmodium berghei Activity 30.0 day 10.1016/j.ejmech.2008.09.044
Plasmodium berghei Plasmodium berghei Activity 35.0 % 10.1021/jm3002795
Plasmodium berghei Plasmodium berghei Activity 40.0 % 10.1021/acs.jmedchem.7b00699
Plasmodium berghei Plasmodium berghei Activity 41.27 % 10.1016/j.ejmech.2021.113271
Plasmodium berghei Plasmodium berghei Activity 53.0 % 10.1016/j.bmcl.2005.10.033
Plasmodium berghei Plasmodium berghei Activity 58.0 % 10.1021/np100737q
Plasmodium berghei Plasmodium berghei Activity 58.3 % 10.1016/j.bmcl.2019.02.029
Plasmodium berghei Plasmodium berghei Activity 75.0 % 10.1128/aac.01304-08
Plasmodium berghei Plasmodium berghei Activity 76.8 % 10.1016/j.ejmech.2020.113084
Plasmodium berghei Plasmodium berghei Activity 80.0 % 10.1021/jm900672t
Plasmodium berghei Plasmodium berghei Activity 83.0 % 10.1021/jm201108k
Plasmodium berghei Plasmodium berghei Activity 83.0 % 10.1021/jm3001373
Plasmodium berghei Plasmodium berghei Activity 84.0 % 10.1016/j.bmc.2019.01.044
Plasmodium berghei Plasmodium berghei Activity 85.0 % 10.1016/j.ejmech.2015.03.011
Plasmodium berghei Plasmodium berghei Activity 86.3 % 10.1016/j.ejmech.2020.113084
Plasmodium berghei Plasmodium berghei Activity 89.0 % 10.1128/aac.01526-09
Plasmodium berghei Plasmodium berghei Activity 89.04 % 10.1016/j.bmcl.2019.02.029
Plasmodium berghei Plasmodium berghei Activity 89.1 % 10.1021/jm701247k
Plasmodium berghei Plasmodium berghei Activity 89.3 % 10.1128/aac.00562-08
Plasmodium berghei Plasmodium berghei Activity 90.6 % 10.1016/j.bmc.2009.01.021
Plasmodium berghei Plasmodium berghei Activity 90.6 % 10.1021/jm0606241
Plasmodium berghei Plasmodium berghei Activity 90.6 % 10.1021/jm070201e
Plasmodium berghei Plasmodium berghei Activity 90.6 % 10.1021/ml400311r
Plasmodium berghei Plasmodium berghei Activity 91.2 % 10.1021/acs.jmedchem.7b01537
Plasmodium berghei Plasmodium berghei Activity 94.0 % 10.1021/np060233p
Plasmodium berghei Plasmodium berghei Activity 94.04 % 10.1016/j.ejmech.2021.113271
Plasmodium berghei Plasmodium berghei Activity 95.7 % 10.1021/np060233p
Plasmodium berghei Plasmodium berghei Activity 97.0 % 10.1021/np100737q
Plasmodium berghei Plasmodium berghei Activity 97.1 % 10.1016/j.ejmech.2018.01.082
Plasmodium berghei Plasmodium berghei Activity 98.0 % 10.1021/jm200694q
Plasmodium berghei Plasmodium berghei Activity 98.0 % 10.1021/jm7012375
Plasmodium berghei Plasmodium berghei Activity 98.4 % 10.1016/j.bmc.2009.01.021
Plasmodium berghei Plasmodium berghei Activity 98.6 % 10.1016/j.bmc.2019.01.016
Plasmodium berghei Plasmodium berghei Activity 98.6 % 10.1021/jm2003359
Plasmodium berghei Plasmodium berghei Activity 98.6 % 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei Activity 98.8 % 10.1128/aac.01526-09
Plasmodium berghei Plasmodium berghei Activity 99.0 % 10.1016/j.bmc.2019.01.044
Plasmodium berghei Plasmodium berghei Activity 99.0 % 10.1016/j.bmc.2020.115832
Plasmodium berghei Plasmodium berghei Activity 99.1 % 10.1021/jm401278d
Plasmodium berghei Plasmodium berghei Activity 99.2 % 10.1021/acsmedchemlett.8b00496
Plasmodium berghei Plasmodium berghei Activity 99.2 % 10.1021/jm801352s
Plasmodium berghei Plasmodium berghei Activity 99.2 % 10.1021/jm9018383
Plasmodium berghei Plasmodium berghei Activity 99.3 % 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei Activity 99.5 % 10.1021/jm100410f
Plasmodium berghei Plasmodium berghei Activity 99.5 % 10.1021/jm1006484
Plasmodium berghei Plasmodium berghei Activity 99.5 % 10.1021/jm201108k
Plasmodium berghei Plasmodium berghei Activity 99.5 % 10.1021/jm300041e
Plasmodium berghei Plasmodium berghei Activity 99.5 % 10.1021/jm3001373
Plasmodium berghei Plasmodium berghei Activity 99.6 % 10.1016/j.bmc.2010.07.046
Plasmodium berghei Plasmodium berghei Activity 99.6 % 10.1016/j.bmc.2017.02.043
Plasmodium berghei Plasmodium berghei Activity 99.6 % 10.1016/j.bmc.2019.03.061
Plasmodium berghei Plasmodium berghei Activity 99.6 % 10.1016/j.ejmech.2017.11.025
Plasmodium berghei Plasmodium berghei Activity 99.6 % 10.1021/jm100410f
Plasmodium berghei Plasmodium berghei Activity 99.6 % 10.1021/jm200227r
Plasmodium berghei Plasmodium berghei Activity 99.6 % 10.1021/jm300041e
Plasmodium berghei Plasmodium berghei Activity 99.6 % 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei Activity 99.7 % 10.1016/j.bmc.2007.05.038
Plasmodium berghei Plasmodium berghei Activity 99.7 % 10.1016/j.bmcl.2009.11.088
Plasmodium berghei Plasmodium berghei Activity 99.7 % 10.1021/jm1006484
Plasmodium berghei Plasmodium berghei Activity 99.7 % 10.1021/jm2003359
Plasmodium berghei Plasmodium berghei Activity 99.7 % 10.1021/jm201108k
Plasmodium berghei Plasmodium berghei Activity 99.7 % 10.1021/jm3001373
Plasmodium berghei Plasmodium berghei Activity 99.7 % 10.1021/jm901473s
Plasmodium berghei Plasmodium berghei Activity 99.7 % 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei Activity 99.8 % 10.1021/jm100410f
Plasmodium berghei Plasmodium berghei Activity 99.8 % 10.1021/jm300041e
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1016/j.bmc.2015.07.051
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/acs.jmedchem.0c01744
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/acs.jmedchem.1c00354
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/acs.jmedchem.2c01516
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/acs.jmedchem.5b01605
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/acs.jmedchem.6b01265
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/acs.jmedchem.7b00140
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/jm1006484
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/jm200227r
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/jm2003359
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/jm201108k
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/jm3001373
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/jm400009c
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/jm401278d
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/jm500535j
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1021/np0496284
Plasmodium berghei Plasmodium berghei Activity 99.9 % 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei Activity 99.97 % 10.1021/jm400009c
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.bmc.2007.05.038
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.bmc.2016.09.013
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.bmcl.2005.10.033
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.bmcl.2012.09.094
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.bmcl.2018.03.058
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.ejmech.2007.03.008
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.ejmech.2007.11.003
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.ejmech.2013.06.002
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.ejmech.2015.04.028
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.ejmech.2021.113685
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.ejmech.2021.113865
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1016/j.ejmech.2022.114774
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1021/acs.jmedchem.8b00143
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1021/acsmedchemlett.8b00496
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1021/jm900672t
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1021/jm901300d
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1021/ml3000808
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1021/np060233p
Plasmodium berghei Plasmodium berghei Activity 100.0 % 10.1128/aac.01304-08
Plasmodium berghei Plasmodium berghei Activity nan None 10.1016/j.bmc.2007.02.027
Plasmodium berghei Plasmodium berghei Activity nan None 10.1016/j.bmc.2015.07.051
Plasmodium berghei Plasmodium berghei Activity nan None 10.1016/j.bmc.2016.09.013
Plasmodium berghei Plasmodium berghei Activity nan None 10.1016/j.bmc.2020.115832
Plasmodium berghei Plasmodium berghei Activity nan None 10.1016/j.bmcl.2018.03.058
Plasmodium berghei Plasmodium berghei Activity nan None 10.1016/j.bmcl.2019.02.029
Plasmodium berghei Plasmodium berghei Activity nan None 10.1016/j.ejmech.2007.03.008
Plasmodium berghei Plasmodium berghei Activity nan None 10.1016/j.ejmech.2007.11.003
Plasmodium berghei Plasmodium berghei Activity nan None 10.1016/j.ejmech.2018.10.041
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/acs.jmedchem.7b00140
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/acs.jmedchem.8b01026
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/acs.jmedchem.9b00504
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/acsmedchemlett.1c00663
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/acsmedchemlett.1c00697
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/acsmedchemlett.8b00496
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/jm100211e
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/jm200302d
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/jm201615t
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/jm501809x
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/ml3000808
Plasmodium berghei Plasmodium berghei Activity nan None 10.1021/np200260f
Plasmodium berghei Plasmodium berghei Activity nan None 10.1039/d2md00392a
Plasmodium berghei Plasmodium berghei Activity nan None 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei Activity nan None 10.1128/aac.00562-08
Plasmodium berghei Plasmodium berghei AUClast nan None 10.1021/jm500715u
Plasmodium berghei Plasmodium berghei Cmax nan None 10.1021/jm500715u
Plasmodium berghei Plasmodium berghei EC50 10000.0 nM 10.1021/jm500066b
Plasmodium berghei Plasmodium berghei ED50 1.0 umol.kg-1 10.1021/jm970686e
Plasmodium berghei Plasmodium berghei ED50 1.1 mg.kg-1 10.1021/acs.jmedchem.8b01799
Plasmodium berghei Plasmodium berghei ED50 1.15 mg/kg/day 10.1021/acs.jmedchem.1c00044
Plasmodium berghei Plasmodium berghei ED50 1.2 umol.kg-1 10.1021/jm970686e
Plasmodium berghei Plasmodium berghei ED50 1.5 mg.kg-1 10.1021/jm020142z
Plasmodium berghei Plasmodium berghei ED50 1.53 mg.kg-1 10.1021/jm0601809
Plasmodium berghei Plasmodium berghei ED50 1.8 mg.kg-1 10.1016/j.ejmech.2021.113193
Plasmodium berghei Plasmodium berghei ED50 1.8 mg.kg-1 10.1021/jm020142z
Plasmodium berghei Plasmodium berghei ED50 1.9 mg.kg-1 10.1016/j.bmcl.2013.03.067
Plasmodium berghei Plasmodium berghei ED50 1.9 mg.kg-1 10.1021/jm201108k
Plasmodium berghei Plasmodium berghei ED50 1.9 mg.kg-1 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei ED50 1.9 mg.kg-1 10.1128/aac.01526-09
Plasmodium berghei Plasmodium berghei ED50 1.9 mg/kg/day 10.1021/jm3002795
Plasmodium berghei Plasmodium berghei ED50 2.0 mg.kg-1 10.1016/j.bmcl.2007.09.044
Plasmodium berghei Plasmodium berghei ED50 3.0 mg.kg-1 10.1021/jm901300d
Plasmodium berghei Plasmodium berghei ED50 3.3 mg.kg-1 10.1021/jm201184h
Plasmodium berghei Plasmodium berghei ED50 4.5 mg.kg-1 10.1016/j.bmc.2009.05.011
Plasmodium berghei Plasmodium berghei ED50 4.5 mg.kg-1 10.1016/j.bmc.2011.11.053
Plasmodium berghei Plasmodium berghei ED50 4.7 umol.kg-1 10.1021/jm010448q
Plasmodium berghei Plasmodium berghei ED50 5.4 mg.kg-1 10.1021/jm0302086
Plasmodium berghei Plasmodium berghei ED50 32.0 mg.kg-1 10.1021/jm0302086
Plasmodium berghei Plasmodium berghei ED90 2.8 mg Kg-1 10.1021/np8004612
Plasmodium berghei Plasmodium berghei ED90 3.0 mg kg-1 10.1021/jm020142z
Plasmodium berghei Plasmodium berghei ED90 3.4 mg kg-1 10.1021/jm020142z
Plasmodium berghei Plasmodium berghei ED90 4.2 mg kg-1 10.1021/jm201108k
Plasmodium berghei Plasmodium berghei ED90 4.2 mg kg-1 10.1128/aac.01526-09
Plasmodium berghei Plasmodium berghei ED90 4.6 mg kg-1 10.1021/jm201184h
Plasmodium berghei Plasmodium berghei ED90 5.0 uM kg-1 10.1021/jm970686e
Plasmodium berghei Plasmodium berghei ED90 9.4 uM kg-1 10.1021/jm010448q
Plasmodium berghei Plasmodium berghei ED90 13.0 mg kg-1 10.1021/jm0302086
Plasmodium berghei Plasmodium berghei ED90 89.0 mg kg-1 10.1021/jm0302086
Plasmodium berghei Plasmodium berghei ED99 8.4 mg kg-1 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei IC50 1.2 nM 10.1016/j.ejmech.2018.01.039
Plasmodium berghei Plasmodium berghei IC50 60.0 nM 10.1016/j.bmcl.2012.09.094
Plasmodium berghei Plasmodium berghei IC50 9000.0 nM 10.1021/acs.jmedchem.5b01374
Plasmodium berghei Plasmodium berghei IC50 10000.0 nM 10.1016/j.ejmech.2014.05.050
Plasmodium berghei Plasmodium berghei IC50 15000.0 nM 10.1016/j.bmcl.2012.12.032
Plasmodium berghei Plasmodium berghei IC50 15900.0 nM 10.1021/jm301654b
Plasmodium berghei Plasmodium berghei IC50 31262.0 nM 10.1021/acs.jmedchem.0c00539
Plasmodium berghei Plasmodium berghei IC50 31262.0 nM 10.1021/acs.jmedchem.8b01961
Plasmodium berghei Plasmodium berghei IC50 nan None 10.1016/j.ejmech.2019.111927
Plasmodium berghei Plasmodium berghei IC50 nan None 10.1021/acs.jmedchem.7b00140
Plasmodium berghei Plasmodium berghei IC50 nan None 10.1021/jm400246e
Plasmodium berghei Plasmodium berghei IC50 nan None 10.1021/jm4011466
Plasmodium berghei Plasmodium berghei ID50 5.0 mg.kg-1 10.1016/j.bmcl.2008.09.030
Plasmodium berghei Plasmodium berghei Inhibition 1.3 % 10.1016/j.bmc.2011.01.050
Plasmodium berghei Plasmodium berghei Inhibition 24.12 % 10.1016/j.bmc.2008.02.011
Plasmodium berghei Plasmodium berghei Inhibition 24.12 % 10.1016/j.bmc.2011.01.050
Plasmodium berghei Plasmodium berghei Inhibition 24.12 % 10.1016/j.ejmech.2008.08.005
Plasmodium berghei Plasmodium berghei Inhibition 40.0 % 10.1016/j.ejmech.2015.08.022
Plasmodium berghei Plasmodium berghei Inhibition 68.0 % 10.1016/j.bmcl.2015.04.014
Plasmodium berghei Plasmodium berghei Inhibition 76.0 % 10.1016/j.bmc.2015.06.056
Plasmodium berghei Plasmodium berghei Inhibition 82.0 % 10.1016/j.bmcl.2015.04.014
Plasmodium berghei Plasmodium berghei Inhibition 82.96 % 10.1016/j.bmcl.2017.03.005
Plasmodium berghei Plasmodium berghei Inhibition 93.0 % 10.1016/j.bmc.2015.06.056
Plasmodium berghei Plasmodium berghei Inhibition 98.0 % 10.1016/j.bmcl.2003.12.069
Plasmodium berghei Plasmodium berghei Inhibition 98.0 % 10.1016/j.bmcl.2013.06.033
Plasmodium berghei Plasmodium berghei Inhibition 98.0 % 10.1016/j.ejmech.2015.08.022
Plasmodium berghei Plasmodium berghei Inhibition 98.9 % 10.1021/jm9018383
Plasmodium berghei Plasmodium berghei Inhibition 99.0 % 10.1016/j.bmcl.2003.12.069
Plasmodium berghei Plasmodium berghei Inhibition 99.0 % 10.1016/j.ejmech.2015.08.022
Plasmodium berghei Plasmodium berghei Inhibition 99.2 % 10.1021/jm7009292
Plasmodium berghei Plasmodium berghei Inhibition 99.6 % 10.1016/j.bmcl.2015.02.044
Plasmodium berghei Plasmodium berghei Inhibition 99.9 % 10.1021/acs.jmedchem.8b01769
Plasmodium berghei Plasmodium berghei Inhibition 99.9 % 10.1021/jm500715u
Plasmodium berghei Plasmodium berghei Inhibition 99.9 % 10.1021/ml100120a
Plasmodium berghei Plasmodium berghei Inhibition 99.97 % 10.1016/j.ejmech.2015.08.044
Plasmodium berghei Plasmodium berghei Inhibition 100.0 % 10.1016/j.bmc.2011.06.025
Plasmodium berghei Plasmodium berghei Inhibition 100.0 % 10.1016/j.ejmech.2014.10.061
Plasmodium berghei Plasmodium berghei Inhibition 100.0 % 10.1016/j.ejmech.2015.08.022
Plasmodium berghei Plasmodium berghei Inhibition 100.0 % 10.1016/j.ejmech.2020.113065
Plasmodium berghei Plasmodium berghei Inhibition 100.0 % 10.1021/jm100211e
Plasmodium berghei Plasmodium berghei Inhibition nan % 10.1016/j.bmcl.2003.12.069
Plasmodium berghei Plasmodium berghei Inhibition nan % 10.1128/aac.01526-09
Plasmodium berghei Plasmodium berghei MCD 40.0 mg kg-1 10.1016/j.bmc.2009.05.011
Plasmodium berghei Plasmodium berghei MCD 40.0 mg kg-1 10.1016/j.bmc.2011.11.053
Plasmodium berghei Plasmodium berghei MCD 80.0 mg kg-1 10.1021/jm00212a010
Plasmodium berghei Plasmodium berghei MED 20.0 mg kg-1 10.1021/jm00212a010
Plasmodium berghei Plasmodium berghei MSD 7.0 day 10.1021/jm201108k
Plasmodium berghei Plasmodium berghei MSD 7.0 day 10.1021/jm3001373
Plasmodium berghei Plasmodium berghei MSD 9.0 day 10.1021/jm201108k
Plasmodium berghei Plasmodium berghei MSD 9.0 day 10.1021/jm3001373
Plasmodium berghei Plasmodium berghei MSD 9.6 day 10.1016/j.bmc.2009.01.021
Plasmodium berghei Plasmodium berghei MSD 10.0 day 10.1021/jm401278d
Plasmodium berghei Plasmodium berghei MSD 11.0 day 10.1016/j.ejmech.2018.04.038
Plasmodium berghei Plasmodium berghei MSD 11.0 day 10.1021/jm400009c
Plasmodium berghei Plasmodium berghei MSD 12.0 day 10.1021/jm201108k
Plasmodium berghei Plasmodium berghei MSD 12.0 day 10.1021/jm3001373
Plasmodium berghei Plasmodium berghei MSD 12.6 day 10.1021/ml100120a
Plasmodium berghei Plasmodium berghei MSD 14.0 day 10.1016/j.bmc.2019.01.016
Plasmodium berghei Plasmodium berghei MSD 16.0 day 10.1016/j.bmc.2015.07.051
Plasmodium berghei Plasmodium berghei MSD 16.0 day 10.1021/jm401278d
Plasmodium berghei Plasmodium berghei MSD 17.0 day 10.1021/jm200227r
Plasmodium berghei Plasmodium berghei MSD 20.0 day 10.1016/j.bmc.2017.02.043
Plasmodium berghei Plasmodium berghei MSD 20.0 day 10.1016/j.bmc.2019.03.061
Plasmodium berghei Plasmodium berghei MSD 20.0 day 10.1016/j.bmcl.2015.02.044
Plasmodium berghei Plasmodium berghei MSD 20.0 day 10.1016/j.ejmech.2017.11.025
Plasmodium berghei Plasmodium berghei MSD 20.0 day 10.1021/jm200227r
Plasmodium berghei Plasmodium berghei MSD 20.0 day 10.1021/jm400009c
Plasmodium berghei Plasmodium berghei MSD 21.0 day 10.1021/acs.jmedchem.0c01744
Plasmodium berghei Plasmodium berghei MSD 22.7 day 10.1016/j.bmc.2009.01.021
Plasmodium berghei Plasmodium berghei MSD 24.0 day 10.1016/j.bmc.2015.07.051
Plasmodium berghei Plasmodium berghei MSD 24.0 day 10.1021/acs.jmedchem.5b01605
Plasmodium berghei Plasmodium berghei MSD 24.0 day 10.1021/acs.jmedchem.6b01265
Plasmodium berghei Plasmodium berghei MSD 24.0 day 10.1021/jm201108k
Plasmodium berghei Plasmodium berghei MSD 24.0 day 10.1021/jm3001373
Plasmodium berghei Plasmodium berghei MSD 24.0 day 10.1021/jm500098s
Plasmodium berghei Plasmodium berghei MSD 25.0 day 10.1021/jm500715u
Plasmodium berghei Plasmodium berghei MSD 29.98 day 10.1016/j.bmc.2017.12.022
Plasmodium berghei Plasmodium berghei MSD 30.0 day 10.1016/j.ejmech.2018.01.082
Plasmodium berghei Plasmodium berghei MSD 30.0 day 10.1021/jm400009c
Plasmodium berghei Plasmodium berghei MSD 60.0 day 10.1016/j.bmcl.2013.06.033
Plasmodium berghei Plasmodium berghei MSD 99.9 day 10.1021/jm500098s
Plasmodium berghei Plasmodium berghei MSD nan None 10.1016/j.bmc.2015.07.051
Plasmodium berghei Plasmodium berghei MST 17.0 day 10.1021/jm300286a
Plasmodium berghei Plasmodium berghei MST 20.7 day 10.1021/jm100211e
Plasmodium berghei Plasmodium berghei MST 21.0 day 10.1021/acs.jmedchem.8b01769
Plasmodium berghei Plasmodium berghei MST 22.0 day 10.1021/jm300286a
Plasmodium berghei Plasmodium berghei MST 24.0 day 10.1021/acs.jmedchem.7b00140
Plasmodium berghei Plasmodium berghei MST 25.6 day 10.1021/acs.jmedchem.5b01374
Plasmodium berghei Plasmodium berghei MST 26.2 day 10.1016/j.ejmech.2014.10.061
Plasmodium berghei Plasmodium berghei MST 28.0 day 10.1021/acsmedchemlett.8b00496
Plasmodium berghei Plasmodium berghei MST 28.0 day 10.1021/ml3000808
Plasmodium berghei Plasmodium berghei MST 31.0 day 10.1021/acs.jmedchem.5b01374
Plasmodium berghei Plasmodium berghei Parasitemia 1.0 % 10.1021/jm010374i
Plasmodium berghei Plasmodium berghei Parasitemia 2.0 % 10.1021/jm010374i
Plasmodium berghei Plasmodium berghei Parasitemia 3.0 % 10.1021/jm010374i
Plasmodium berghei Plasmodium berghei Parasitemia 7.0 % 10.1021/jm010374i
Plasmodium berghei Plasmodium berghei Parasitemia 18.0 % 10.1021/jm010374i
Plasmodium berghei Plasmodium berghei Parasitemia 20.0 % 10.1021/jm010374i
Plasmodium berghei Plasmodium berghei Parasitemia 21.0 % 10.1021/jm010374i
Plasmodium berghei Plasmodium berghei Survival 6.0 day 10.1016/j.bmc.2009.02.050
Plasmodium berghei Plasmodium berghei Survival 8.0 % 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei Survival 8.7 day 10.1021/jm2003359
Plasmodium berghei Plasmodium berghei Survival 8.7 day 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei Survival 9.0 day 10.1021/jm100410f
Plasmodium berghei Plasmodium berghei Survival 9.0 day 10.1021/jm1006484
Plasmodium berghei Plasmodium berghei Survival 9.0 day 10.1021/jm300041e
Plasmodium berghei Plasmodium berghei Survival 9.4 day 10.1016/j.bmcl.2009.11.088
Plasmodium berghei Plasmodium berghei Survival 9.4 day 10.1021/jm901473s
Plasmodium berghei Plasmodium berghei Survival 10.0 day 10.1021/jm1006484
Plasmodium berghei Plasmodium berghei Survival 12.0 day 10.1021/jm2003359
Plasmodium berghei Plasmodium berghei Survival 12.0 day 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei Survival 12.5 day 10.1021/jm100410f
Plasmodium berghei Plasmodium berghei Survival 12.5 day 10.1021/jm300041e
Plasmodium berghei Plasmodium berghei Survival 13.6 day 10.1021/jm100410f
Plasmodium berghei Plasmodium berghei Survival 13.6 day 10.1021/jm300041e
Plasmodium berghei Plasmodium berghei Survival 14.3 day 10.1021/jm100410f
Plasmodium berghei Plasmodium berghei Survival 15.4 day 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei Survival 16.3 day 10.1021/jm801352s
Plasmodium berghei Plasmodium berghei Survival 18.8 day 10.1021/jm2003359
Plasmodium berghei Plasmodium berghei Survival 18.8 day 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei Survival 20.0 % 10.1021/acs.jmedchem.5b00678
Plasmodium berghei Plasmodium berghei Survival 20.0 day 10.1016/j.ejmech.2015.08.044
Plasmodium berghei Plasmodium berghei Survival 22.1 day 10.1128/aac.01526-09
Plasmodium berghei Plasmodium berghei Survival 23.0 day 10.1016/j.ejmech.2015.04.028
Plasmodium berghei Plasmodium berghei Survival 23.0 day 10.1021/jm1006484
Plasmodium berghei Plasmodium berghei Survival 24.0 day 10.1016/j.bmc.2019.01.044
Plasmodium berghei Plasmodium berghei Survival 25.5 day 10.1128/aac.01526-09
Plasmodium berghei Plasmodium berghei Survival 27.0 day 10.1021/jm500535j
Plasmodium berghei Plasmodium berghei Survival 29.4 day 10.1016/j.bmc.2015.05.040
Plasmodium berghei Plasmodium berghei Survival 30.0 day 10.1016/j.bmc.2008.02.011
Plasmodium berghei Plasmodium berghei Survival 30.0 day 10.1016/j.bmc.2011.01.050
Plasmodium berghei Plasmodium berghei Survival 30.0 day 10.1021/acs.jmedchem.8b00143
Plasmodium berghei Plasmodium berghei Survival 100.0 % 10.1016/j.ejmech.2013.06.002
Plasmodium berghei Plasmodium berghei Survival 100.0 % 10.1021/acs.jmedchem.5b00678
Plasmodium berghei Plasmodium berghei Survival 100.0 % 10.1021/acs.jmedchem.7b00621
Plasmodium berghei Plasmodium berghei Survival nan None 10.1016/j.ejmech.2013.06.002
Plasmodium berghei Plasmodium berghei Survival nan None 10.1021/jm200694q
Plasmodium berghei Plasmodium berghei Survival nan None 10.1126/science.1193225
Plasmodium berghei Plasmodium berghei t1/2 nan None 10.1021/jm500715u
Plasmodium berghei Plasmodium berghei T-C 8.7 day 10.1021/jm00089a025
Plasmodium berghei Plasmodium berghei T-C 60.0 day 10.1021/jm00089a025
Plasmodium berghei Plasmodium berghei TIME 599.76 hr 10.1016/j.ejmech.2021.113865
Plasmodium berghei Plasmodium berghei TIME 628.8 hr 10.1016/j.ejmech.2021.113865
Plasmodium berghei Plasmodium berghei TIME 672.0 hr 10.1128/aac.01304-08
Plasmodium berghei Plasmodium berghei TIME 705.6 hr 10.1016/j.ejmech.2017.10.051
Plasmodium chabaudi Plasmodium chabaudi Activity 6.9 % 10.1021/jm070733v
Plasmodium chabaudi Plasmodium chabaudi Activity 99.9 % 10.1021/jm801352s
Plasmodium chabaudi Plasmodium chabaudi Activity 100.0 % 10.1021/jm701247k
Plasmodium chabaudi Plasmodium chabaudi Activity nan None 10.1016/j.bmcl.2011.06.085
Plasmodium chabaudi Plasmodium chabaudi Activity nan None 10.1128/aac.01329-07
Plasmodium chabaudi Plasmodium chabaudi Inhibition 95.0 % 10.1021/acs.jmedchem.8b01972
Plasmodium chabaudi Plasmodium chabaudi Inhibition 99.9 % 10.1021/acsmedchemlett.9b00123
Plasmodium chabaudi Plasmodium chabaudi Inhibition 99.99 % 10.1021/ml400412x
Plasmodium cynomolgi Plasmodium cynomolgi TIME 264.0 hr 10.1016/j.bmc.2010.12.028
Plasmodium cynomolgi Plasmodium cynomolgi TIME 264.0 hr 10.1021/jm200111g
Plasmodium falciparum Chloroquine resistance transporter Inhibition nan % 10.1021/jm2009698
Plasmodium falciparum Cysteine protease falcipain-3 IC50 nan None 10.1016/j.ejmech.2011.01.008
Plasmodium falciparum Cysteine protease falcipain-3 IC50 nan None 10.1021/acs.jmedchem.9b00504
Plasmodium falciparum Falcipain 2 IC50 20.0 nM 10.1016/j.bmcl.2018.03.058
Plasmodium falciparum Falcipain 2 IC50 200.0 nM 10.1016/j.bmcl.2018.03.058
Plasmodium falciparum Falcipain 2 IC50 nan nM 10.1021/jm058208o
Plasmodium falciparum Falcipain 2 IC50 nan None 10.1016/j.ejmech.2011.01.008
Plasmodium falciparum Falcipain 2 IC50 nan None 10.1021/acs.jmedchem.9b00504
Plasmodium falciparum Falcipain 2 Ratio IC50 0.01 None 10.1016/j.bmcl.2018.03.058
Plasmodium falciparum Ferriprotoporphyrin IX IC50 8.5 ug.mL-1 10.1016/s0960-894x(03)00509-2
Plasmodium falciparum Ferriprotoporphyrin IX IC50 17900.0 nM 10.1021/jm7013088
Plasmodium falciparum Ferriprotoporphyrin IX IC50 28000.0 nM 10.1016/s0960-894x(03)00509-2
Plasmodium falciparum Ferriprotoporphyrin IX Index 100.0 % 10.1016/s0960-894x(03)00509-2
Plasmodium falciparum Ferriprotoporphyrin IX log K 5.52 None 10.1021/acs.jmedchem.6b00719
Plasmodium falciparum Ferriprotoporphyrin IX Log K 5.52 None 10.1021/jm031132g
Plasmodium falciparum Ferriprotoporphyrin IX Log K 5.52 None 10.1021/jm990437l
Plasmodium falciparum Hemozoin Activity 5.0 fg 10.1021/acs.jmedchem.6b00719
Plasmodium falciparum Hemozoin Activity 15.0 fg 10.1021/acs.jmedchem.6b00719
Plasmodium falciparum Hemozoin Activity 68.2 % 10.1021/acs.jnatprod.0c01032
Plasmodium falciparum Hemozoin IC50 1.91 equiv 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Hemozoin IC50 16800.0 nM 10.1016/j.bmcl.2021.128442
Plasmodium falciparum Hemozoin IC50 16900.0 nM 10.1039/c9md00468h
Plasmodium falciparum Hemozoin IC50 18000.0 nM 10.1021/acs.jmedchem.8b01769
Plasmodium falciparum Hemozoin IC50 19000.0 nM 10.1021/acs.jmedchem.0c02022
Plasmodium falciparum Hemozoin IC50 21000.0 nM 10.1021/acs.jmedchem.0c01411
Plasmodium falciparum Hemozoin IC50 22000.0 nM 10.1021/acs.jmedchem.2c01516
Plasmodium falciparum Hemozoin IC50 31500.0 nM 10.1021/acs.jmedchem.6b00719
Plasmodium falciparum Hemozoin IC50 53000.0 nM 10.1021/acs.jmedchem.6b00719
Plasmodium falciparum Hemozoin IC50 53000.0 nM 10.1039/C8MD00608C
Plasmodium falciparum Hemozoin IC50 74000.0 nM 10.1016/j.ejmech.2019.06.069
Plasmodium falciparum Hemozoin IC50 800000.0 nM 10.1016/j.bmc.2016.09.013
Plasmodium falciparum Hemozoin IC50 890000.0 nM 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Hemozoin INH 6.6 uM 10.1021/acs.jmedchem.6b00028
Plasmodium falciparum Hemozoin Inhibition 52.1 % 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Hemozoin Inhibition nan % 10.1016/j.ejmech.2020.112889
Plasmodium falciparum Hemozoin Inhibition nan % 10.1021/acs.jmedchem.0c00858
Plasmodium falciparum Histidine-rich protein Activity 84.16 % 10.1016/j.ejmech.2008.09.044
Plasmodium falciparum Histidine-rich protein Activity nan None 10.1021/jm7012375
Plasmodium falciparum Histidine-rich protein Activity nan None 10.1128/aac.00239-07
Plasmodium falciparum Histidine-rich protein IC50 1.78 molar ratio 10.1021/jm8012757
Plasmodium falciparum Histidine-rich protein IC50 2.56 milliequivalent 10.1021/jm801490z
Plasmodium falciparum Histidine-rich protein IC50 4.87 ug.mL-1 10.1016/j.bmcl.2009.03.026
Plasmodium falciparum Histidine-rich protein IC50 76.5 nM 10.1021/jm020960r
Plasmodium falciparum Histidine-rich protein IC50 400.0 nM 10.1021/jm061002i
Plasmodium falciparum Histidine-rich protein IC50 15000.0 nM 10.1021/jm9902180
Plasmodium falciparum Histidine-rich protein IC50 15400.0 nM 10.1128/aac.00288-07
Plasmodium falciparum Histidine-rich protein IC50 38000.0 nM 10.1021/jm0108707
Plasmodium falciparum Histidine-rich protein IC50 46300.0 nM 10.1021/jm060259d
Plasmodium falciparum Histidine-rich protein IC50 60000.0 nM 10.1016/j.bmcl.2005.09.058
Plasmodium falciparum Histidine-rich protein IC50 75000.0 nM 10.1016/s0960-894x(01)00383-3
Plasmodium falciparum Histidine-rich protein IC50 76500.0 nM 10.1016/j.bmcl.2003.07.008
Plasmodium falciparum Histidine-rich protein IC50 252000.0 nM 10.1128/aac.00985-06
Plasmodium falciparum Histidine-rich protein IC50 910000000.0 nM 10.1016/j.bmcl.2006.07.060
Plasmodium falciparum Histidine-rich protein IC50 1690000000.0 nM 10.1021/jm061429p
Plasmodium falciparum Histidine-rich protein IC50 2560000000.0 nM 10.1021/np0496284
Plasmodium falciparum Histidine-rich protein Inhibition 55.0 uM 10.1016/j.bmcl.2004.06.056
Plasmodium falciparum Histidine-rich protein Inhibition 86.25 % 10.1016/j.ejmech.2007.01.001
Plasmodium falciparum Histidine-rich protein Inhibition 86.6 % 10.1016/j.bmc.2008.02.011
Plasmodium falciparum Histidine-rich protein Inhibition 86.6 % 10.1016/j.ejmech.2008.08.005
Plasmodium falciparum Histidine-rich protein Inhibition 86.6 % 10.1021/jm058208o
Plasmodium falciparum Histidine-rich protein Inhibition nan % 10.1016/j.bmcl.2004.01.070
Plasmodium falciparum Histidine-rich protein Inhibition nan % 10.1021/jm031132g
Plasmodium falciparum Histidine-rich protein Inhibition nan % 10.1021/jm990437l
Plasmodium falciparum Histidine-rich protein Ratio 2.5 None 10.1021/jm801352s
Plasmodium falciparum Histidine-rich protein VAR 5310.0 None 10.1016/j.bmcl.2003.07.008
Plasmodium falciparum Phosphoethanolamine N-methyltransferase IC50 554000.0 nM 10.1016/j.bmcl.2012.06.032
Plasmodium falciparum Plasmepsin 2 Ki nan None 10.1016/j.bmcl.2012.07.069
Plasmodium falciparum Plasmodium falciparum Accumulation coefficient 18.0 None 10.1021/jm011046l
Plasmodium falciparum Plasmodium falciparum Accumulation coefficient 191.0 None 10.1021/jm011046l
Plasmodium falciparum Plasmodium falciparum Activity 0.0 % 10.1016/j.ejmech.2012.06.046
Plasmodium falciparum Plasmodium falciparum Activity 0.0 % 10.1021/jm200302d
Plasmodium falciparum Plasmodium falciparum Activity 0.0 % 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Activity 0.06 % 10.1016/j.ejmech.2012.06.046
Plasmodium falciparum Plasmodium falciparum Activity 0.06 % 10.1021/jm200302d
Plasmodium falciparum Plasmodium falciparum Activity 0.06 uM 10.1016/j.bmcl.2005.07.090
Plasmodium falciparum Plasmodium falciparum Activity 0.145 uM 10.1016/j.bmcl.2005.07.090
Plasmodium falciparum Plasmodium falciparum Activity 0.2 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 0.25 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 0.37 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 0.52 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 0.53 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 0.56 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 0.65 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 0.75 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 0.82 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.0 % 10.1016/j.bmc.2012.06.038
Plasmodium falciparum Plasmodium falciparum Activity 1.09 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.11 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.12 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.13 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.22 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.26 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.38 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.51 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.62 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.64 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.72 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.78 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.82 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.83 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 1.85 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 2.17 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 3.05 None 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum Activity 3.2 % 10.1128/aac.00610-09
Plasmodium falciparum Plasmodium falciparum Activity 5.0 % 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Activity 5.0 mg kg-1 10.1021/jm00196a019
Plasmodium falciparum Plasmodium falciparum Activity 5.24 % 10.1016/j.bmc.2009.08.057
Plasmodium falciparum Plasmodium falciparum Activity 7.0 nM 10.1016/j.bmc.2014.12.018
Plasmodium falciparum Plasmodium falciparum Activity 8.0 % 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Activity 12.0 % 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Activity 15.0 % 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum Activity 20.0 mg kg-1 10.1021/jm00196a019
Plasmodium falciparum Plasmodium falciparum Activity 23.0 % 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Activity 25.9 % 10.1016/j.bmc.2017.06.047
Plasmodium falciparum Plasmodium falciparum Activity 26.92 % 10.1016/j.ejmech.2008.09.044
Plasmodium falciparum Plasmodium falciparum Activity 36.0 % 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Activity 54.0 % 10.1007/s00044-010-9397-z
Plasmodium falciparum Plasmodium falciparum Activity 67.0 % 10.1007/s00044-012-0371-9
Plasmodium falciparum Plasmodium falciparum Activity 67.8 % 10.1021/np9605394
Plasmodium falciparum Plasmodium falciparum Activity 68.0 % 10.1021/jm901474p
Plasmodium falciparum Plasmodium falciparum Activity 68.5 % 10.1007/s00044-010-9460-9
Plasmodium falciparum Plasmodium falciparum Activity 74.3 % 10.1016/j.ejmech.2009.11.022
Plasmodium falciparum Plasmodium falciparum Activity 84.0 % 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Activity 85.0 % 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Activity 86.3 % 10.1016/j.bmc.2009.08.057
Plasmodium falciparum Plasmodium falciparum Activity 90.0 % 10.1021/jm5019719
Plasmodium falciparum Plasmodium falciparum Activity 96.0 % 10.1021/jm901540n
Plasmodium falciparum Plasmodium falciparum Activity 97.0 % 10.1021/jm901540n
Plasmodium falciparum Plasmodium falciparum Activity 97.1 % 10.1016/j.ejmech.2009.11.022
Plasmodium falciparum Plasmodium falciparum Activity 99.6 % 10.1016/j.bmc.2013.06.059
Plasmodium falciparum Plasmodium falciparum Activity 99.6 % 10.1021/jm7013088
Plasmodium falciparum Plasmodium falciparum Activity 99.9 % 10.1021/jm400004u
Plasmodium falciparum Plasmodium falciparum Activity 100.0 % 10.1016/j.ejmech.2009.11.022
Plasmodium falciparum Plasmodium falciparum Activity 100.0 % 10.1016/j.ejmech.2020.112666
Plasmodium falciparum Plasmodium falciparum Activity 100.0 % 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum Activity 102.0 nM 10.1016/j.bmc.2014.12.018
Plasmodium falciparum Plasmodium falciparum Activity 145.0 nM 10.1016/j.bmc.2014.12.018
Plasmodium falciparum Plasmodium falciparum Activity 735.0 nM 10.1016/j.bmc.2014.12.018
Plasmodium falciparum Plasmodium falciparum Activity 3000.0 % 10.1021/np9605394
Plasmodium falciparum Plasmodium falciparum Activity 3700.0 None 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum Activity 23000.0 None 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1016/j.bmc.2011.06.002
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1016/j.bmcl.2010.11.099
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1016/j.bmcl.2011.05.131
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1021/acs.jmedchem.0c01755
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1021/acs.jmedchem.0c02022
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1021/acs.jmedchem.1c00044
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1021/acs.jmedchem.7b01537
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1021/acsmedchemlett.0c00196
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1021/jm400004u
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1021/jm500535j
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1021/ml300008j
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1021/ml400306r
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1128/aac.00519-09
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1128/aac.00808-06
Plasmodium falciparum Plasmodium falciparum Activity nan None 10.1128/aac.01479-06
Plasmodium falciparum Plasmodium falciparum AUCED90 3.1 uM.hr/day 10.1021/acs.jmedchem.6b00275
Plasmodium falciparum Plasmodium falciparum CD90 2.0 mg kg-1 10.1021/jm00196a019
Plasmodium falciparum Plasmodium falciparum CD90 5.0 mg kg-1 10.1021/jm00196a019
Plasmodium falciparum Plasmodium falciparum CD90 20.0 mg kg-1 10.1021/jm00196a019
Plasmodium falciparum Plasmodium falciparum EC50 0.0475 ug.mL-1 10.1021/jm0601809
Plasmodium falciparum Plasmodium falciparum EC50 0.095 nM 10.1021/jm400009c
Plasmodium falciparum Plasmodium falciparum EC50 0.1 ug.mL-1 10.1016/j.ejmech.2015.08.044
Plasmodium falciparum Plasmodium falciparum EC50 0.11 ug.mL-1 10.1021/jm500191u
Plasmodium falciparum Plasmodium falciparum EC50 0.375 ug.mL-1 10.1021/jm0601809
Plasmodium falciparum Plasmodium falciparum EC50 0.67 nM 10.1021/ml200160k
Plasmodium falciparum Plasmodium falciparum EC50 2.426 nM 10.1073/pnas.0802982105
Plasmodium falciparum Plasmodium falciparum EC50 3.0 nM 10.1021/jm500797g
Plasmodium falciparum Plasmodium falciparum EC50 4.0 nM 10.1016/j.ejmech.2021.113253
Plasmodium falciparum Plasmodium falciparum EC50 6.0 nM 10.1016/j.ejmech.2013.05.007
Plasmodium falciparum Plasmodium falciparum EC50 6.0 nM 10.1016/j.ejmech.2018.05.022
Plasmodium falciparum Plasmodium falciparum EC50 6.0 nM 10.1021/jm500066b
Plasmodium falciparum Plasmodium falciparum EC50 7.0 nM 10.1016/j.bmcl.2008.10.083
Plasmodium falciparum Plasmodium falciparum EC50 7.0 nM 10.1021/acsmedchemlett.1c00697
Plasmodium falciparum Plasmodium falciparum EC50 7.0 nM 10.1021/jm301328h
Plasmodium falciparum Plasmodium falciparum EC50 7.1 nM 10.1021/jm200265b
Plasmodium falciparum Plasmodium falciparum EC50 8.0 nM 10.1016/j.bmcl.2008.02.037
Plasmodium falciparum Plasmodium falciparum EC50 8.9 nM 10.1021/acsmedchemlett.8b00245
Plasmodium falciparum Plasmodium falciparum EC50 9.0 nM 10.1021/jm0493717
Plasmodium falciparum Plasmodium falciparum EC50 9.4 nM 10.1016/j.bmcl.2010.02.022
Plasmodium falciparum Plasmodium falciparum EC50 9.8 nM 10.1016/j.bmc.2018.05.041
Plasmodium falciparum Plasmodium falciparum EC50 9.8 nM 10.1016/j.ejmech.2018.03.076
Plasmodium falciparum Plasmodium falciparum EC50 9.8 nM 10.1016/j.ejmech.2019.03.004
Plasmodium falciparum Plasmodium falciparum EC50 9.8 nM 10.1016/j.ejmech.2021.113193
Plasmodium falciparum Plasmodium falciparum EC50 10.0 nM 10.1038/nchembio.87
Plasmodium falciparum Plasmodium falciparum EC50 10.0 nM 10.1039/C4MD00409D
Plasmodium falciparum Plasmodium falciparum EC50 10.0 nM 10.1128/aac.01418-06
Plasmodium falciparum Plasmodium falciparum EC50 12.0 nM 10.1016/j.bmc.2016.03.027
Plasmodium falciparum Plasmodium falciparum EC50 13.0 nM 10.1016/j.bmc.2018.10.029
Plasmodium falciparum Plasmodium falciparum EC50 13.0 nM 10.1021/acs.jmedchem.5b00515
Plasmodium falciparum Plasmodium falciparum EC50 13.0 nM 10.1021/jm500066b
Plasmodium falciparum Plasmodium falciparum EC50 14.0 nM 10.1007/s00044-006-0142-6
Plasmodium falciparum Plasmodium falciparum EC50 14.0 nM 10.1016/j.bmcl.2003.11.055
Plasmodium falciparum Plasmodium falciparum EC50 14.0 nM 10.1016/j.bmcl.2008.10.083
Plasmodium falciparum Plasmodium falciparum EC50 14.0 nM 10.1021/acs.jmedchem.0c02022
Plasmodium falciparum Plasmodium falciparum EC50 14.0 nM 10.1021/jm400009c
Plasmodium falciparum Plasmodium falciparum EC50 16.9 nM 10.1021/acs.jmedchem.9b00363
Plasmodium falciparum Plasmodium falciparum EC50 17.0 nM 10.1016/j.bmcl.2004.12.037
Plasmodium falciparum Plasmodium falciparum EC50 17.8 nM 10.1021/acs.jmedchem.0c00858
Plasmodium falciparum Plasmodium falciparum EC50 18.0 nM 10.1016/j.bmc.2008.04.051
Plasmodium falciparum Plasmodium falciparum EC50 18.0 nM 10.1016/j.bmc.2014.02.040
Plasmodium falciparum Plasmodium falciparum EC50 18.0 nM 10.1016/j.bmcl.2006.02.030
Plasmodium falciparum Plasmodium falciparum EC50 18.0 nM 10.1021/jm000952f
Plasmodium falciparum Plasmodium falciparum EC50 18.0 nM 10.1021/jm0155704
Plasmodium falciparum Plasmodium falciparum EC50 18.0 nM 10.1021/jm0201971
Plasmodium falciparum Plasmodium falciparum EC50 18.0 nM 10.1021/jm0302086
Plasmodium falciparum Plasmodium falciparum EC50 18.0 nM 10.1021/jm990131e
Plasmodium falciparum Plasmodium falciparum EC50 20.0 nM 10.1016/j.bmcl.2010.06.099
Plasmodium falciparum Plasmodium falciparum EC50 20.0 nM 10.1021/acs.jmedchem.6b01673
Plasmodium falciparum Plasmodium falciparum EC50 21.0 nM 10.1021/acs.jmedchem.0c02022
Plasmodium falciparum Plasmodium falciparum EC50 21.0 nM 10.1021/ml300419r
Plasmodium falciparum Plasmodium falciparum EC50 23.0 nM 10.1016/j.bmcl.2014.09.061
Plasmodium falciparum Plasmodium falciparum EC50 23.0 nM 10.1016/j.ejmech.2015.07.047
Plasmodium falciparum Plasmodium falciparum EC50 23.0 nM 10.1021/acs.jmedchem.6b01673
Plasmodium falciparum Plasmodium falciparum EC50 23.0 nM 10.1128/aac.01512-09
Plasmodium falciparum Plasmodium falciparum EC50 25.0 nM 10.1128/aac.01512-09
Plasmodium falciparum Plasmodium falciparum EC50 28.97 ppm 10.1016/j.bmc.2019.06.038
Plasmodium falciparum Plasmodium falciparum EC50 28.97 ppm 10.1016/j.ejmech.2017.02.012
Plasmodium falciparum Plasmodium falciparum EC50 30.0 nM 10.1016/j.ejmech.2010.08.026
Plasmodium falciparum Plasmodium falciparum EC50 30.0 nM 10.1021/jm200636z
Plasmodium falciparum Plasmodium falciparum EC50 33.0 nM 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum EC50 46.0 nM 10.1016/j.bmcl.2008.10.083
Plasmodium falciparum Plasmodium falciparum EC50 49.0 nM 10.1016/j.bmcl.2013.03.067
Plasmodium falciparum Plasmodium falciparum EC50 52.0 nM 10.1016/j.bmcl.2008.10.083
Plasmodium falciparum Plasmodium falciparum EC50 55.0 nM 10.1128/aac.00840-06
Plasmodium falciparum Plasmodium falciparum EC50 57.0 nM 10.1021/acs.jmedchem.7b00405
Plasmodium falciparum Plasmodium falciparum EC50 59.0 nM 10.1007/s00044-005-0126-y
Plasmodium falciparum Plasmodium falciparum EC50 59.0 nM 10.1021/acs.jmedchem.6b01673
Plasmodium falciparum Plasmodium falciparum EC50 66.0 nM 10.1016/j.bmcl.2008.10.083
Plasmodium falciparum Plasmodium falciparum EC50 83.7 nM 10.1073/pnas.0802982105
Plasmodium falciparum Plasmodium falciparum EC50 90.0 nM 10.1016/j.bmc.2010.02.013
Plasmodium falciparum Plasmodium falciparum EC50 97.0 nM 10.1016/j.ejmech.2021.113253
Plasmodium falciparum Plasmodium falciparum EC50 100.0 nM 10.1016/j.bmc.2011.02.012
Plasmodium falciparum Plasmodium falciparum EC50 100.0 nM 10.1016/j.bmc.2013.07.004
Plasmodium falciparum Plasmodium falciparum EC50 112.0 nM 10.1021/acsmedchemlett.3c00039
Plasmodium falciparum Plasmodium falciparum EC50 120.0 nM 10.1021/ml300419r
Plasmodium falciparum Plasmodium falciparum EC50 130.0 nM 10.1021/jm990131e
Plasmodium falciparum Plasmodium falciparum EC50 131.0 nM 10.1021/jm200015a
Plasmodium falciparum Plasmodium falciparum EC50 131.0 nM 10.1021/jm200718m
Plasmodium falciparum Plasmodium falciparum EC50 140.0 nM 10.1021/jm400009c
Plasmodium falciparum Plasmodium falciparum EC50 150.0 nM 10.1021/jm0606241
Plasmodium falciparum Plasmodium falciparum EC50 158.49 nM 10.1021/acs.jmedchem.0c01104
Plasmodium falciparum Plasmodium falciparum EC50 162.0 nM 10.1021/jm200015a
Plasmodium falciparum Plasmodium falciparum EC50 162.0 nM 10.1021/jm200718m
Plasmodium falciparum Plasmodium falciparum EC50 163.9 nM 10.1021/jm1007903
Plasmodium falciparum Plasmodium falciparum EC50 165.3 nM 10.1016/j.bmcl.2020.127514
Plasmodium falciparum Plasmodium falciparum EC50 165.3 nM 10.1016/j.ejmech.2020.112955
Plasmodium falciparum Plasmodium falciparum EC50 165.3 nM 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Plasmodium falciparum EC50 174.0 nM 10.1021/acs.jmedchem.0c00858
Plasmodium falciparum Plasmodium falciparum EC50 208.0 nM 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum EC50 221.0 nM 10.1021/jm5009693
Plasmodium falciparum Plasmodium falciparum EC50 229.0 nM 10.1021/acs.jmedchem.6b00759
Plasmodium falciparum Plasmodium falciparum EC50 229.0 nM 10.1021/jm500942v
Plasmodium falciparum Plasmodium falciparum EC50 229.09 nM 10.1021/acs.jmedchem.0c01104
Plasmodium falciparum Plasmodium falciparum EC50 230.0 nM 10.1021/acs.jmedchem.7b00738
Plasmodium falciparum Plasmodium falciparum EC50 250.0 nM 10.1016/j.ejmech.2021.113253
Plasmodium falciparum Plasmodium falciparum EC50 250.0 nM 10.1021/acs.jmedchem.6b01673
Plasmodium falciparum Plasmodium falciparum EC50 250.0 nM 10.1021/jm400009c
Plasmodium falciparum Plasmodium falciparum EC50 255.0 nM 10.1021/jm500066b
Plasmodium falciparum Plasmodium falciparum EC50 260.0 nM 10.1021/jm400009c
Plasmodium falciparum Plasmodium falciparum EC50 280.0 nM 10.1021/jm0493717
Plasmodium falciparum Plasmodium falciparum EC50 285.0 nM 10.1016/j.ejmech.2015.07.047
Plasmodium falciparum Plasmodium falciparum EC50 286.0 nM 10.1021/acs.jmedchem.6b01673
Plasmodium falciparum Plasmodium falciparum EC50 293.0 nM 10.1128/aac.01418-06
Plasmodium falciparum Plasmodium falciparum EC50 302.8 nM 10.1016/j.bmcl.2020.127514
Plasmodium falciparum Plasmodium falciparum EC50 302.8 nM 10.1016/j.ejmech.2020.112955
Plasmodium falciparum Plasmodium falciparum EC50 310.0 nM 10.1007/s00044-006-0142-6
Plasmodium falciparum Plasmodium falciparum EC50 310.0 nM 10.1016/j.bmcl.2003.11.055
Plasmodium falciparum Plasmodium falciparum EC50 319.0 nM 10.1021/acsmedchemlett.1c00697
Plasmodium falciparum Plasmodium falciparum EC50 320.0 nM 10.1016/j.ejmech.2021.113253
Plasmodium falciparum Plasmodium falciparum EC50 328.0 nM 10.1021/jm500066b
Plasmodium falciparum Plasmodium falciparum EC50 359.0 nM 10.1007/s00044-005-0126-y
Plasmodium falciparum Plasmodium falciparum EC50 382.0 nM 10.1016/j.bmcl.2004.12.037
Plasmodium falciparum Plasmodium falciparum EC50 420.0 nM 10.1021/acs.jmedchem.7b00738
Plasmodium falciparum Plasmodium falciparum EC50 421.0 nM 10.1021/acs.jmedchem.6b00759
Plasmodium falciparum Plasmodium falciparum EC50 421.0 nM 10.1021/jm500942v
Plasmodium falciparum Plasmodium falciparum EC50 470.0 nM 10.1021/acsmedchemlett.8b00543
Plasmodium falciparum Plasmodium falciparum EC50 560.0 nM 10.1016/j.ejmech.2021.113253
Plasmodium falciparum Plasmodium falciparum EC50 580.0 nM 10.1016/j.ejmech.2021.113253
Plasmodium falciparum Plasmodium falciparum EC50 608.0 nM 10.1021/acs.jmedchem.6b01673
Plasmodium falciparum Plasmodium falciparum EC50 643.0 nM 10.1021/acs.jmedchem.6b01673
Plasmodium falciparum Plasmodium falciparum EC50 690.0 nM 10.1016/j.bmcl.2014.09.061
Plasmodium falciparum Plasmodium falciparum EC50 800.0 nM 10.1016/j.ejmech.2021.113722
Plasmodium falciparum Plasmodium falciparum EC50 1000.0 nM 10.1021/jm200636z
Plasmodium falciparum Plasmodium falciparum EC50 1500.0 nM 10.1021/jm070201e
Plasmodium falciparum Plasmodium falciparum EC50 1610.0 nM 10.1016/j.bmc.2010.02.013
Plasmodium falciparum Plasmodium falciparum EC50 2970.0 nM 10.1016/j.ejmech.2018.01.082
Plasmodium falciparum Plasmodium falciparum EC50 10000.0 nM 10.1016/j.ejmech.2021.113253
Plasmodium falciparum Plasmodium falciparum EC50 11250.0 nM 10.1016/j.ejmech.2018.01.082
Plasmodium falciparum Plasmodium falciparum EC50 21000.0 nM 10.1016/j.ejmech.2021.113253
Plasmodium falciparum Plasmodium falciparum EC50 40000.0 nM 10.1021/acs.jmedchem.6b01673
Plasmodium falciparum Plasmodium falciparum EC50 48200.0 nM 10.1021/jm1007903
Plasmodium falciparum Plasmodium falciparum EC50 nan None 10.1128/aac.00840-06
Plasmodium falciparum Plasmodium falciparum ED50 0.002 ug ml-1 10.1016/s0960-894x(01)00528-5
Plasmodium falciparum Plasmodium falciparum ED50 0.003 uM 10.1021/jm060290f
Plasmodium falciparum Plasmodium falciparum ED50 0.15 ug ml-1 10.1016/s0960-894x(01)00528-5
Plasmodium falciparum Plasmodium falciparum ED50 1.3 ng/ml 10.1021/np50099a005
Plasmodium falciparum Plasmodium falciparum ED50 1.3 ug ml-1 10.1021/np50098a017
Plasmodium falciparum Plasmodium falciparum ED50 2.0 mg.kg-1 10.1021/ml2001517
Plasmodium falciparum Plasmodium falciparum ED50 2.5 ng/ml 10.1021/np50091a005
Plasmodium falciparum Plasmodium falciparum ED50 2.8 mg.kg-1 10.1021/acsmedchemlett.7b00391
Plasmodium falciparum Plasmodium falciparum ED50 3.2 mg.kg-1 10.1021/jm200592f
Plasmodium falciparum Plasmodium falciparum ED50 3.5 ng/ml 10.1021/np50112a013
Plasmodium falciparum Plasmodium falciparum ED50 5.0 nM 10.1021/jm0491039
Plasmodium falciparum Plasmodium falciparum ED50 5.8 nM 10.1021/jm0504860
Plasmodium falciparum Plasmodium falciparum ED50 8.0 ng ml-1 10.1021/jm020244p
Plasmodium falciparum Plasmodium falciparum ED50 8.0 nM 10.1021/jm0491039
Plasmodium falciparum Plasmodium falciparum ED50 8.52 nM 10.1016/j.bmc.2007.07.012
Plasmodium falciparum Plasmodium falciparum ED50 11.2 ng/ml 10.1021/np50099a005
Plasmodium falciparum Plasmodium falciparum ED50 11.2 ug ml-1 10.1021/np50098a017
Plasmodium falciparum Plasmodium falciparum ED50 14.3 nM 10.1021/jm010268g
Plasmodium falciparum Plasmodium falciparum ED50 19.0 nM 10.1021/jm010268g
Plasmodium falciparum Plasmodium falciparum ED50 20.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum ED50 31.7 ng/ml 10.1021/np50091a005
Plasmodium falciparum Plasmodium falciparum ED50 36.5 ng/ml 10.1021/np50112a013
Plasmodium falciparum Plasmodium falciparum ED50 54.0 nM 10.1021/jm010268g
Plasmodium falciparum Plasmodium falciparum ED50 78.0 nM 10.1021/jm0491039
Plasmodium falciparum Plasmodium falciparum ED50 125.0 nM 10.1021/jm0491039
Plasmodium falciparum Plasmodium falciparum ED50 126.0 nM 10.1021/jm010268g
Plasmodium falciparum Plasmodium falciparum ED50 175.0 nM 10.1021/jm010268g
Plasmodium falciparum Plasmodium falciparum ED50 183.0 nM 10.1021/jm010268g
Plasmodium falciparum Plasmodium falciparum ED50 200.0 nM 10.1021/jm0491039
Plasmodium falciparum Plasmodium falciparum ED50 220.0 ng ml-1 10.1021/jm020244p
Plasmodium falciparum Plasmodium falciparum ED50 290.0 nM 10.1016/j.bmc.2007.07.012
Plasmodium falciparum Plasmodium falciparum ED50 1030.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum ED90 4.3 mg kg-1 10.1021/acs.jmedchem.5b01605
Plasmodium falciparum Plasmodium falciparum ED90 4.3 mg kg-1 10.1021/acs.jmedchem.6b00275
Plasmodium falciparum Plasmodium falciparum ED90 4.4 mg Kg-1 10.1128/aac.00519-09
Plasmodium falciparum Plasmodium falciparum ED90 4.9 mg kg-1 10.1021/jm200592f
Plasmodium falciparum Plasmodium falciparum ED90 4.9 mg Kg-1 10.1128/aac.00519-09
Plasmodium falciparum Plasmodium falciparum ED90 6.4 mg/kg/day 10.1016/j.bmcl.2013.03.067
Plasmodium falciparum Plasmodium falciparum ED90 50.0 mg Kg-1 10.1128/aac.00519-09
Plasmodium falciparum Plasmodium falciparum GI 10.0 % 10.1128/aac.00544-08
Plasmodium falciparum Plasmodium falciparum GI 58.2 % 10.1016/j.ejmech.2015.02.040
Plasmodium falciparum Plasmodium falciparum GI 99.0 % 10.1016/j.ejmech.2021.113253
Plasmodium falciparum Plasmodium falciparum GI nan None 10.1007/s00044-004-0117-4
Plasmodium falciparum Plasmodium falciparum GI nan None 10.1128/aac.00544-08
Plasmodium falciparum Plasmodium falciparum IC10 2.01 ng ml-1 10.1016/S0960-894X(00)80047-5
Plasmodium falciparum Plasmodium falciparum IC10 52.65 ng ml-1 10.1016/S0960-894X(00)80047-5
Plasmodium falciparum Plasmodium falciparum IC50 0.001 ug.mL-1 10.1016/j.bmcl.2013.06.035
Plasmodium falciparum Plasmodium falciparum IC50 0.0012 ug.mL-1 10.1021/np8004612
Plasmodium falciparum Plasmodium falciparum IC50 0.0013 ug.mL-1 10.1021/np000436s
Plasmodium falciparum Plasmodium falciparum IC50 0.0013 ug.mL-1 10.1021/np9605394
Plasmodium falciparum Plasmodium falciparum IC50 0.0016 ug.mL-1 10.1021/np049626j
Plasmodium falciparum Plasmodium falciparum IC50 0.0016 ug.mL-1 10.1021/np9602325
Plasmodium falciparum Plasmodium falciparum IC50 0.0019 ug.mL-1 10.1021/np50077a020
Plasmodium falciparum Plasmodium falciparum IC50 0.00195 ug.mL-1 10.1021/np50090a014
Plasmodium falciparum Plasmodium falciparum IC50 0.002 ug.mL-1 10.1016/j.bmc.2008.11.005
Plasmodium falciparum Plasmodium falciparum IC50 0.002 ug.mL-1 10.1016/j.bmc.2008.11.021
Plasmodium falciparum Plasmodium falciparum IC50 0.002 ug.mL-1 10.1016/j.ejmech.2013.08.008
Plasmodium falciparum Plasmodium falciparum IC50 0.00212 ug.mL-1 10.1016/S0960-894X(01)81211-7
Plasmodium falciparum Plasmodium falciparum IC50 0.0023 ug.mL-1 10.1021/np9605246
Plasmodium falciparum Plasmodium falciparum IC50 0.00245 ug.mL-1 10.1016/j.bmc.2012.03.011
Plasmodium falciparum Plasmodium falciparum IC50 0.00245 ug.mL-1 10.1016/j.bmcl.2012.10.101
Plasmodium falciparum Plasmodium falciparum IC50 0.00245 ug.mL-1 10.1039/C1MD00188D
Plasmodium falciparum Plasmodium falciparum IC50 0.00254 ug.mL-1 10.1021/np000306j
Plasmodium falciparum Plasmodium falciparum IC50 0.0026 ug.mL-1 10.1016/j.bmcl.2008.10.049
Plasmodium falciparum Plasmodium falciparum IC50 0.0026 ug.mL-1 10.1021/jm00013a001
Plasmodium falciparum Plasmodium falciparum IC50 0.00269 ug.mL-1 10.1016/S0960-894X(00)80047-5
Plasmodium falciparum Plasmodium falciparum IC50 0.0029 ug.mL-1 10.1021/np50101a014
Plasmodium falciparum Plasmodium falciparum IC50 0.00296 ug.mL-1 10.1021/jm061232x
Plasmodium falciparum Plasmodium falciparum IC50 0.003 ug.mL-1 10.1016/j.ejmech.2021.113545
Plasmodium falciparum Plasmodium falciparum IC50 0.003 ug.mL-1 10.1021/np010037c
Plasmodium falciparum Plasmodium falciparum IC50 0.003 ug.mL-1 10.1021/np050510c
Plasmodium falciparum Plasmodium falciparum IC50 0.003 ug.mL-1 10.1021/np800338p
Plasmodium falciparum Plasmodium falciparum IC50 0.0031 ug.mL-1 10.1021/jm00126a017
Plasmodium falciparum Plasmodium falciparum IC50 0.0032 ug.mL-1 10.1021/np000199t
Plasmodium falciparum Plasmodium falciparum IC50 0.0034 ug.mL-1 10.1021/np960195h
Plasmodium falciparum Plasmodium falciparum IC50 0.004 ug.mL-1 10.1016/j.bmc.2012.04.061
Plasmodium falciparum Plasmodium falciparum IC50 0.004 ug.mL-1 10.1016/j.bmcl.2005.09.008
Plasmodium falciparum Plasmodium falciparum IC50 0.004 ug.mL-1 10.1021/np990555b
Plasmodium falciparum Plasmodium falciparum IC50 0.0041 ug.mL-1 10.1128/aac.01607-06
Plasmodium falciparum Plasmodium falciparum IC50 0.004174 ug.mL-1 10.1021/jm0504252
Plasmodium falciparum Plasmodium falciparum IC50 0.0043 ug.mL-1 10.1039/C8MD00382C
Plasmodium falciparum Plasmodium falciparum IC50 0.0044 ug.mL-1 10.1021/np000247+
Plasmodium falciparum Plasmodium falciparum IC50 0.0046 ug.mL-1 10.1021/np9704157
Plasmodium falciparum Plasmodium falciparum IC50 0.0046 ug.mL-1 10.1021/np990502u
Plasmodium falciparum Plasmodium falciparum IC50 0.0049 ug.mL-1 10.1021/np0101752
Plasmodium falciparum Plasmodium falciparum IC50 0.005 ug.mL-1 10.1016/j.bmc.2012.04.061
Plasmodium falciparum Plasmodium falciparum IC50 0.005 ug.mL-1 10.1016/j.bmcl.2005.09.008
Plasmodium falciparum Plasmodium falciparum IC50 0.005 ug.mL-1 10.1021/jm0110892
Plasmodium falciparum Plasmodium falciparum IC50 0.005 ug.mL-1 10.1021/np049640w
Plasmodium falciparum Plasmodium falciparum IC50 0.0051 ug.mL-1 10.1021/np800338p
Plasmodium falciparum Plasmodium falciparum IC50 0.0052 ug.mL-1 10.1016/j.bmc.2009.05.075
Plasmodium falciparum Plasmodium falciparum IC50 0.0052 ug.mL-1 10.1016/j.bmcl.2009.03.026
Plasmodium falciparum Plasmodium falciparum IC50 0.0052 ug.mL-1 10.1016/j.bmcl.2012.04.100
Plasmodium falciparum Plasmodium falciparum IC50 0.0052 ug.mL-1 10.1039/C3MD00310H
Plasmodium falciparum Plasmodium falciparum IC50 0.0055 ug.mL-1 10.1021/np0497088
Plasmodium falciparum Plasmodium falciparum IC50 0.006 ug.mL-1 10.1016/j.bmcl.2008.05.035
Plasmodium falciparum Plasmodium falciparum IC50 0.006 ug.mL-1 10.1016/j.ejmech.2012.07.018
Plasmodium falciparum Plasmodium falciparum IC50 0.006 ug.mL-1 10.1021/jm020104f
Plasmodium falciparum Plasmodium falciparum IC50 0.006 ug.mL-1 10.1021/np960013j
Plasmodium falciparum Plasmodium falciparum IC50 0.0061 ug.mL-1 10.1016/j.bmc.2008.11.048
Plasmodium falciparum Plasmodium falciparum IC50 0.0061 ug.mL-1 10.1021/np8007107
Plasmodium falciparum Plasmodium falciparum IC50 0.0064 ug.mL-1 10.1021/jm990002y
Plasmodium falciparum Plasmodium falciparum IC50 0.007 ug.mL-1 10.1016/j.bmc.2006.11.024
Plasmodium falciparum Plasmodium falciparum IC50 0.007 ug.mL-1 10.1021/np0202226
Plasmodium falciparum Plasmodium falciparum IC50 0.00736 ug.mL-1 10.1021/jm020142z
Plasmodium falciparum Plasmodium falciparum IC50 0.00758 ug.mL-1 10.1021/jm020142z
Plasmodium falciparum Plasmodium falciparum IC50 0.0076 ug.mL-1 10.1021/np50034a027
Plasmodium falciparum Plasmodium falciparum IC50 0.008 ug.mL-1 10.1016/j.bmc.2010.09.071
Plasmodium falciparum Plasmodium falciparum IC50 0.008 ug.mL-1 10.1016/j.bmcl.2003.12.104
Plasmodium falciparum Plasmodium falciparum IC50 0.0081 ug.mL-1 10.1128/aac.01607-06
Plasmodium falciparum Plasmodium falciparum IC50 0.0094 ug.mL-1 10.1128/aac.01607-06
Plasmodium falciparum Plasmodium falciparum IC50 0.01 ug.mL-1 10.1021/np030077b
Plasmodium falciparum Plasmodium falciparum IC50 0.01 ug.mL-1 10.1021/np0340549
Plasmodium falciparum Plasmodium falciparum IC50 0.01 ug.mL-1 10.1021/np1000939
Plasmodium falciparum Plasmodium falciparum IC50 0.01 ug.mL-1 10.1021/np900334k
Plasmodium falciparum Plasmodium falciparum IC50 0.01 ug.mL-1 10.1021/np990604k
Plasmodium falciparum Plasmodium falciparum IC50 0.0103 ug.mL-1 10.1021/np0701071
Plasmodium falciparum Plasmodium falciparum IC50 0.0104 ug.mL-1 10.1128/aac.01607-06
Plasmodium falciparum Plasmodium falciparum IC50 0.011 ug.mL-1 10.1016/j.ejmech.2018.01.039
Plasmodium falciparum Plasmodium falciparum IC50 0.011 ug well-1 10.1016/s0960-894x(02)00802-8
Plasmodium falciparum Plasmodium falciparum IC50 0.012 ug.mL-1 10.1021/jm100507q
Plasmodium falciparum Plasmodium falciparum IC50 0.013 ug.mL-1 10.1016/s0960-894x(03)00509-2
Plasmodium falciparum Plasmodium falciparum IC50 0.01347 ug.mL-1 10.1016/j.bmc.2015.05.009
Plasmodium falciparum Plasmodium falciparum IC50 0.014 ug.mL-1 10.1016/j.bmc.2006.10.036
Plasmodium falciparum Plasmodium falciparum IC50 0.014 ug.mL-1 10.1016/j.bmc.2010.11.036
Plasmodium falciparum Plasmodium falciparum IC50 0.014 ug.mL-1 10.1016/j.ejmech.2012.03.019
Plasmodium falciparum Plasmodium falciparum IC50 0.014 ug.mL-1 10.1021/np800163u
Plasmodium falciparum Plasmodium falciparum IC50 0.014 ug.mL-1 10.1039/C0MD00267D
Plasmodium falciparum Plasmodium falciparum IC50 0.015 ug.mL-1 10.1016/j.bmcl.2013.02.075
Plasmodium falciparum Plasmodium falciparum IC50 0.015 ug.mL-1 10.1021/np030045o
Plasmodium falciparum Plasmodium falciparum IC50 0.0155 ug.mL-1 10.1021/np020592u
Plasmodium falciparum Plasmodium falciparum IC50 0.0155 ug.mL-1 10.1021/np0400095
Plasmodium falciparum Plasmodium falciparum IC50 0.0155 ug.mL-1 10.1021/np0601399
Plasmodium falciparum Plasmodium falciparum IC50 0.016 ug.mL-1 10.1007/s00044-011-9798-7
Plasmodium falciparum Plasmodium falciparum IC50 0.016 ug.mL-1 10.1016/j.ejmech.2017.11.043
Plasmodium falciparum Plasmodium falciparum IC50 0.016 ug.mL-1 10.1021/jm900672t
Plasmodium falciparum Plasmodium falciparum IC50 0.017 ug.mL-1 10.1016/j.bmc.2009.10.042
Plasmodium falciparum Plasmodium falciparum IC50 0.017 ug.mL-1 10.1021/np800653z
Plasmodium falciparum Plasmodium falciparum IC50 0.018 ug.mL-1 10.1021/np010216u
Plasmodium falciparum Plasmodium falciparum IC50 0.018 ug.mL-1 10.1021/np030086k
Plasmodium falciparum Plasmodium falciparum IC50 0.018 ug.mL-1 10.1021/np030524n
Plasmodium falciparum Plasmodium falciparum IC50 0.019 ug.mL-1 10.1021/np000436s
Plasmodium falciparum Plasmodium falciparum IC50 0.019 ug.mL-1 10.1021/np0102861
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1016/j.bmc.2016.02.028
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1016/j.bmc.2017.10.041
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1016/j.bmc.2019.06.038
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1016/j.bmcl.2016.06.038
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1016/j.bmcl.2021.127819
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1016/j.ejmech.2014.02.015
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1016/j.ejmech.2014.07.008
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1016/j.ejmech.2017.02.012
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1016/j.ejmech.2020.112652
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1021/np400908u
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1021/np800333r
Plasmodium falciparum Plasmodium falciparum IC50 0.02 ug.mL-1 10.1039/d2md00076h
Plasmodium falciparum Plasmodium falciparum IC50 0.0223 ug.mL-1 10.1007/s00044-011-9694-1
Plasmodium falciparum Plasmodium falciparum IC50 0.0228 ug.mL-1 10.1021/np50090a014
Plasmodium falciparum Plasmodium falciparum IC50 0.023 ug.mL-1 10.1021/np0680230
Plasmodium falciparum Plasmodium falciparum IC50 0.026 ug.mL-1 10.1016/j.bmc.2009.01.011
Plasmodium falciparum Plasmodium falciparum IC50 0.027 ug.mL-1 10.1021/np2002012
Plasmodium falciparum Plasmodium falciparum IC50 0.0295 ug.mL-1 10.1021/np000436s
Plasmodium falciparum Plasmodium falciparum IC50 0.0295 ug.mL-1 10.1021/np9605394
Plasmodium falciparum Plasmodium falciparum IC50 0.0299 ug.mL-1 10.1021/np9602325
Plasmodium falciparum Plasmodium falciparum IC50 0.03 nM 10.1016/j.ejmech.2009.02.008
Plasmodium falciparum Plasmodium falciparum IC50 0.03 ug.mL-1 10.1021/np800333r
Plasmodium falciparum Plasmodium falciparum IC50 0.03186 ug.mL-1 10.1021/jm061232x
Plasmodium falciparum Plasmodium falciparum IC50 0.033 ug.mL-1 10.1021/np050510c
Plasmodium falciparum Plasmodium falciparum IC50 0.03457 ug.mL-1 10.1021/jm0504252
Plasmodium falciparum Plasmodium falciparum IC50 0.035 ug.mL-1 10.1021/np8004612
Plasmodium falciparum Plasmodium falciparum IC50 0.038 ug.mL-1 10.1021/np010037c
Plasmodium falciparum Plasmodium falciparum IC50 0.04 nM 10.1021/np900144c
Plasmodium falciparum Plasmodium falciparum IC50 0.04 ug.mL-1 10.1016/j.ejmech.2021.113193
Plasmodium falciparum Plasmodium falciparum IC50 0.04 ug.mL-1 10.1021/np0497245
Plasmodium falciparum Plasmodium falciparum IC50 0.041 ug.mL-1 10.1021/np0497651
Plasmodium falciparum Plasmodium falciparum IC50 0.042 ug.mL-1 10.1021/np000199t
Plasmodium falciparum Plasmodium falciparum IC50 0.0436 ug.mL-1 10.1021/jm00126a017
Plasmodium falciparum Plasmodium falciparum IC50 0.044 ug.mL-1 10.1021/np0340549
Plasmodium falciparum Plasmodium falciparum IC50 0.048 ug.mL-1 10.1021/jm970401y
Plasmodium falciparum Plasmodium falciparum IC50 0.05003 ug.mL-1 10.1016/S0960-894X(01)81211-7
Plasmodium falciparum Plasmodium falciparum IC50 0.0518 ug.mL-1 10.1021/np960195h
Plasmodium falciparum Plasmodium falciparum IC50 0.054 ug.mL-1 10.1021/np990555b
Plasmodium falciparum Plasmodium falciparum IC50 0.05445 ug.mL-1 10.1128/aac.01023-06
Plasmodium falciparum Plasmodium falciparum IC50 0.055 ug.mL-1 10.1021/np030077b
Plasmodium falciparum Plasmodium falciparum IC50 0.056 ug.mL-1 10.1016/j.bmc.2010.08.055
Plasmodium falciparum Plasmodium falciparum IC50 0.058 ug.mL-1 10.1021/np000306j
Plasmodium falciparum Plasmodium falciparum IC50 0.06 nM 10.1021/jm00398a026
Plasmodium falciparum Plasmodium falciparum IC50 0.06 ug.mL-1 10.1021/np50034a027
Plasmodium falciparum Plasmodium falciparum IC50 0.06 ug.mL-1 10.1021/np800333r
Plasmodium falciparum Plasmodium falciparum IC50 0.06 ug.mL-1 10.1021/np900528m
Plasmodium falciparum Plasmodium falciparum IC50 0.0611 ug.mL-1 10.1021/np9704157
Plasmodium falciparum Plasmodium falciparum IC50 0.062 ug.mL-1 10.1021/np800338p
Plasmodium falciparum Plasmodium falciparum IC50 0.0632 ug.mL-1 10.1021/np50101a014
Plasmodium falciparum Plasmodium falciparum IC50 0.065 ug.mL-1 10.1021/np000247+
Plasmodium falciparum Plasmodium falciparum IC50 0.0664 ug.mL-1 10.1021/np0101752
Plasmodium falciparum Plasmodium falciparum IC50 0.068 ug.mL-1 10.1021/np9605246
Plasmodium falciparum Plasmodium falciparum IC50 0.07 ug.mL-1 10.1021/jm010089z
Plasmodium falciparum Plasmodium falciparum IC50 0.07002 ug.mL-1 10.1016/S0960-894X(00)80047-5
Plasmodium falciparum Plasmodium falciparum IC50 0.072 ug.mL-1 10.1021/np9605246
Plasmodium falciparum Plasmodium falciparum IC50 0.073 ug.mL-1 10.1016/j.ejmech.2011.12.028
Plasmodium falciparum Plasmodium falciparum IC50 0.0747 ug.mL-1 10.1021/np50077a020
Plasmodium falciparum Plasmodium falciparum IC50 0.079 ug.mL-1 10.1021/np800294q
Plasmodium falciparum Plasmodium falciparum IC50 0.07901 ug.mL-1 10.1021/jm020142z
Plasmodium falciparum Plasmodium falciparum IC50 0.083 ug.mL-1 10.1039/C8MD00382C
Plasmodium falciparum Plasmodium falciparum IC50 0.084 ug.mL-1 10.1021/np800338p
Plasmodium falciparum Plasmodium falciparum IC50 0.085 ug.mL-1 10.1016/j.ejmech.2011.09.025
Plasmodium falciparum Plasmodium falciparum IC50 0.086 ug.mL-1 10.1016/j.ejmech.2008.10.003
Plasmodium falciparum Plasmodium falciparum IC50 0.091 ug.mL-1 10.1021/jm0110892
Plasmodium falciparum Plasmodium falciparum IC50 0.091 ug.mL-1 10.1021/jm970401y
Plasmodium falciparum Plasmodium falciparum IC50 0.091 ug.mL-1 10.1021/np049640w
Plasmodium falciparum Plasmodium falciparum IC50 0.091 ug.mL-1 10.1021/np990502u
Plasmodium falciparum Plasmodium falciparum IC50 0.092 ug.mL-1 10.1016/s0960-894x(00)00604-1
Plasmodium falciparum Plasmodium falciparum IC50 0.09716 ug.mL-1 10.1128/aac.01607-06
Plasmodium falciparum Plasmodium falciparum IC50 0.1 ug.mL-1 10.1016/j.bmc.2006.10.036
Plasmodium falciparum Plasmodium falciparum IC50 0.1 ug.mL-1 10.1016/j.bmc.2010.11.036
Plasmodium falciparum Plasmodium falciparum IC50 0.1 ug.mL-1 10.1016/j.ejmech.2012.03.019
Plasmodium falciparum Plasmodium falciparum IC50 0.1 ug.mL-1 10.1021/np1000939
Plasmodium falciparum Plasmodium falciparum IC50 0.1 ug.mL-1 10.1021/np2004825
Plasmodium falciparum Plasmodium falciparum IC50 0.1 ug.mL-1 10.1021/np800104p
Plasmodium falciparum Plasmodium falciparum IC50 0.1 ug.mL-1 10.1021/np900334k
Plasmodium falciparum Plasmodium falciparum IC50 0.1 ug.mL-1 10.1021/np960013j
Plasmodium falciparum Plasmodium falciparum IC50 0.1 ug.mL-1 10.1039/C0MD00267D
Plasmodium falciparum Plasmodium falciparum IC50 0.11 nM 10.1016/j.ejmech.2015.01.012
Plasmodium falciparum Plasmodium falciparum IC50 0.11 ug.mL-1 10.1021/jm2015183
Plasmodium falciparum Plasmodium falciparum IC50 0.11 ug.mL-1 10.1021/np0497088
Plasmodium falciparum Plasmodium falciparum IC50 0.113 ug.mL-1 10.1016/j.ejmech.2010.04.011
Plasmodium falciparum Plasmodium falciparum IC50 0.113 ug.mL-1 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 0.113 ug.mL-1 10.1021/jm0304562
Plasmodium falciparum Plasmodium falciparum IC50 0.114 ug.mL-1 10.1021/jm020104f
Plasmodium falciparum Plasmodium falciparum IC50 0.115 ug.mL-1 10.1016/j.bmc.2006.11.024
Plasmodium falciparum Plasmodium falciparum IC50 0.117 ug.mL-1 10.1016/j.bmcl.2014.07.050
Plasmodium falciparum Plasmodium falciparum IC50 0.118 ug.mL-1 10.1021/jm020142z
Plasmodium falciparum Plasmodium falciparum IC50 0.1246 ug.mL-1 10.1128/aac.01607-06
Plasmodium falciparum Plasmodium falciparum IC50 0.125 ug.mL-1 10.1016/j.bmc.2009.10.042
Plasmodium falciparum Plasmodium falciparum IC50 0.1257 ug.mL-1 10.1021/jm0504252
Plasmodium falciparum Plasmodium falciparum IC50 0.1304 ug.mL-1 10.1128/aac.01607-06
Plasmodium falciparum Plasmodium falciparum IC50 0.1399 ug.mL-1 10.1016/j.bmc.2015.05.009
Plasmodium falciparum Plasmodium falciparum IC50 0.14 ug.mL-1 10.1016/j.bmc.2006.10.062
Plasmodium falciparum Plasmodium falciparum IC50 0.14 ug.mL-1 10.1016/j.ejmech.2008.04.009
Plasmodium falciparum Plasmodium falciparum IC50 0.14 ug.mL-1 10.1016/j.ejmech.2017.11.043
Plasmodium falciparum Plasmodium falciparum IC50 0.14 ug.mL-1 10.1021/np000436s
Plasmodium falciparum Plasmodium falciparum IC50 0.14 ug.mL-1 10.1021/np0102861
Plasmodium falciparum Plasmodium falciparum IC50 0.14 ug.mL-1 10.1021/np030045o
Plasmodium falciparum Plasmodium falciparum IC50 0.14 ug.mL-1 10.1021/np800333r
Plasmodium falciparum Plasmodium falciparum IC50 0.14 ug.mL-1 10.1021/np800653z
Plasmodium falciparum Plasmodium falciparum IC50 0.1415 ug.mL-1 10.1016/j.bmcl.2012.10.101
Plasmodium falciparum Plasmodium falciparum IC50 0.1438 ug.mL-1 10.1021/jm061232x
Plasmodium falciparum Plasmodium falciparum IC50 0.147 ug.mL-1 10.1021/jm100507q
Plasmodium falciparum Plasmodium falciparum IC50 0.155 ug.mL-1 10.1007/s00044-011-9798-7
Plasmodium falciparum Plasmodium falciparum IC50 0.155 ug.mL-1 10.1021/jm900672t
Plasmodium falciparum Plasmodium falciparum IC50 0.155 ug.mL-1 10.1021/np800163u
Plasmodium falciparum Plasmodium falciparum IC50 0.1608 ug.mL-1 10.1021/jm990002y
Plasmodium falciparum Plasmodium falciparum IC50 0.17 ug.mL-1 10.1021/np020592u
Plasmodium falciparum Plasmodium falciparum IC50 0.17 ug.mL-1 10.1021/np0400095
Plasmodium falciparum Plasmodium falciparum IC50 0.17 ug.mL-1 10.1021/np0496284
Plasmodium falciparum Plasmodium falciparum IC50 0.17 ug.mL-1 10.1021/np0601399
Plasmodium falciparum Plasmodium falciparum IC50 0.1767 ug.mL-1 10.1021/np030086k
Plasmodium falciparum Plasmodium falciparum IC50 0.1767 ug.mL-1 10.1021/np030524n
Plasmodium falciparum Plasmodium falciparum IC50 0.184 ug.mL-1 10.1016/j.bmcl.2013.02.075
Plasmodium falciparum Plasmodium falciparum IC50 0.19 ug.mL-1 10.1016/j.bmcl.2015.04.014
Plasmodium falciparum Plasmodium falciparum IC50 0.19 ug.mL-1 10.1021/np8005953
Plasmodium falciparum Plasmodium falciparum IC50 0.194 ug.mL-1 10.1021/jm970401y
Plasmodium falciparum Plasmodium falciparum IC50 0.22 ug.mL-1 10.1016/j.bmcl.2003.12.104
Plasmodium falciparum Plasmodium falciparum IC50 0.22 ug.mL-1 10.1016/j.bmcl.2005.10.033
Plasmodium falciparum Plasmodium falciparum IC50 0.22 ug.mL-1 10.1021/np010216u
Plasmodium falciparum Plasmodium falciparum IC50 0.22 ug.mL-1 10.1021/np010419i
Plasmodium falciparum Plasmodium falciparum IC50 0.22 ug.mL-1 10.1021/np0202226
Plasmodium falciparum Plasmodium falciparum IC50 0.224 ug.mL-1 10.1016/j.bmc.2009.05.011
Plasmodium falciparum Plasmodium falciparum IC50 0.2301 ug.mL-1 10.1007/s00044-011-9694-1
Plasmodium falciparum Plasmodium falciparum IC50 0.24 ug.mL-1 10.1016/j.ejmech.2018.01.039
Plasmodium falciparum Plasmodium falciparum IC50 0.2485 ug.mL-1 10.1128/aac.01607-06
Plasmodium falciparum Plasmodium falciparum IC50 0.25 ug.mL-1 10.1016/j.bmcl.2009.02.120
Plasmodium falciparum Plasmodium falciparum IC50 0.2559 ug.mL-1 10.1039/C1MD00188D
Plasmodium falciparum Plasmodium falciparum IC50 0.2677 ug.mL-1 10.1128/aac.01607-06
Plasmodium falciparum Plasmodium falciparum IC50 0.2746 ug.mL-1 10.1128/aac.01607-06
Plasmodium falciparum Plasmodium falciparum IC50 0.3315 ug.mL-1 10.1128/aac.01607-06
Plasmodium falciparum Plasmodium falciparum IC50 0.39 ug.mL-1 10.1016/j.bmcl.2015.04.014
Plasmodium falciparum Plasmodium falciparum IC50 0.405 ug.mL-1 10.1016/j.ejmech.2016.07.055
Plasmodium falciparum Plasmodium falciparum IC50 0.501 ug.mL-1 10.1021/jm970401y
Plasmodium falciparum Plasmodium falciparum IC50 0.54 ug.mL-1 10.1016/j.ejmech.2012.12.013
Plasmodium falciparum Plasmodium falciparum IC50 0.6 ug.mL-1 10.1016/j.ejmech.2012.07.018
Plasmodium falciparum Plasmodium falciparum IC50 0.8 ug.mL-1 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Plasmodium falciparum IC50 0.97 nM 10.1021/jm00398a026
Plasmodium falciparum Plasmodium falciparum IC50 1.241 ug.mL-1 10.1021/jm970401y
Plasmodium falciparum Plasmodium falciparum IC50 1.4 nM 10.1016/j.ejmech.2012.03.007
Plasmodium falciparum Plasmodium falciparum IC50 2.0 nM 10.1016/j.bmcl.2011.05.119
Plasmodium falciparum Plasmodium falciparum IC50 2.0 nM 10.1021/np300773x
Plasmodium falciparum Plasmodium falciparum IC50 2.4 nM 10.1016/j.bmc.2007.05.038
Plasmodium falciparum Plasmodium falciparum IC50 2.62 ug.mL-1 10.1021/jm970401y
Plasmodium falciparum Plasmodium falciparum IC50 2.813 ug.mL-1 10.1021/jm970401y
Plasmodium falciparum Plasmodium falciparum IC50 3.0 nM 10.1016/j.bmcl.2014.12.048
Plasmodium falciparum Plasmodium falciparum IC50 3.0 nM 10.1016/j.ejmech.2019.111927
Plasmodium falciparum Plasmodium falciparum IC50 3.0 nM 10.1016/j.ejmech.2020.112837
Plasmodium falciparum Plasmodium falciparum IC50 3.0 nM 10.1016/j.ejmech.2021.113687
Plasmodium falciparum Plasmodium falciparum IC50 3.0 nM 10.1021/jm0002578
Plasmodium falciparum Plasmodium falciparum IC50 3.0 nM 10.1021/jm401675a
Plasmodium falciparum Plasmodium falciparum IC50 3.02 nM 10.1016/j.ejmech.2020.112837
Plasmodium falciparum Plasmodium falciparum IC50 3.8 nM 10.1016/j.ejmech.2015.02.011
Plasmodium falciparum Plasmodium falciparum IC50 3.8 nM 10.1021/acsmedchemlett.2c00531
Plasmodium falciparum Plasmodium falciparum IC50 3.9 nM 10.1016/j.bmc.2016.12.006
Plasmodium falciparum Plasmodium falciparum IC50 3.9 nM 10.1016/j.bmc.2017.02.043
Plasmodium falciparum Plasmodium falciparum IC50 3.9 nM 10.1021/jm301614w
Plasmodium falciparum Plasmodium falciparum IC50 4.0 nM 10.1016/j.ejmech.2017.11.025
Plasmodium falciparum Plasmodium falciparum IC50 4.0 nM 10.1021/acs.jmedchem.1c00044
Plasmodium falciparum Plasmodium falciparum IC50 4.0 nM 10.1021/acs.jmedchem.2c01516
Plasmodium falciparum Plasmodium falciparum IC50 4.0 nM 10.1021/acs.jmedchem.8b01333
Plasmodium falciparum Plasmodium falciparum IC50 4.0 nM 10.1021/acs.jmedchem.8b01799
Plasmodium falciparum Plasmodium falciparum IC50 4.0 nM 10.1021/acs.jmedchem.9b00504
Plasmodium falciparum Plasmodium falciparum IC50 4.0 nM 10.1021/acs.jnatprod.8b01031
Plasmodium falciparum Plasmodium falciparum IC50 4.0 nM 10.1021/acsmedchemlett.1c00328
Plasmodium falciparum Plasmodium falciparum IC50 4.0 nM 10.1021/jm200227r
Plasmodium falciparum Plasmodium falciparum IC50 4.0 ug.mL-1 10.1021/np050315y
Plasmodium falciparum Plasmodium falciparum IC50 4.2 nM 10.1016/j.bmcl.2019.126778
Plasmodium falciparum Plasmodium falciparum IC50 4.2 nM 10.1128/aac.00808-06
Plasmodium falciparum Plasmodium falciparum IC50 4.3 nM 10.1021/acs.jnatprod.5b00581
Plasmodium falciparum Plasmodium falciparum IC50 4.36 nM 10.1016/j.ejmech.2022.114774
Plasmodium falciparum Plasmodium falciparum IC50 4.5 nM 10.1021/acs.jnatprod.6b00759
Plasmodium falciparum Plasmodium falciparum IC50 4.5 nM 10.1021/acs.jnatprod.9b00721
Plasmodium falciparum Plasmodium falciparum IC50 4.6 nM 10.1021/jm901796s
Plasmodium falciparum Plasmodium falciparum IC50 4.69 nM 10.1016/j.ejmech.2019.111983
Plasmodium falciparum Plasmodium falciparum IC50 4.7 nM 10.1021/acs.jnatprod.0c00245
Plasmodium falciparum Plasmodium falciparum IC50 4.7 nM 10.1021/np800406q
Plasmodium falciparum Plasmodium falciparum IC50 4.75 nM 10.1016/j.bmc.2014.09.009
Plasmodium falciparum Plasmodium falciparum IC50 4.8 nM 10.1021/jm00036a014
Plasmodium falciparum Plasmodium falciparum IC50 4.8 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 4.8 nM 10.1128/aac.00808-06
Plasmodium falciparum Plasmodium falciparum IC50 4.9 nM 10.1039/C8MD00098K
Plasmodium falciparum Plasmodium falciparum IC50 4.9 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 5.0 nM 10.1016/j.bmc.2013.06.067
Plasmodium falciparum Plasmodium falciparum IC50 5.0 nM 10.1016/j.bmcl.2015.08.030
Plasmodium falciparum Plasmodium falciparum IC50 5.0 nM 10.1016/j.ejmech.2014.05.073
Plasmodium falciparum Plasmodium falciparum IC50 5.0 nM 10.1016/j.ejmech.2017.07.052
Plasmodium falciparum Plasmodium falciparum IC50 5.0 nM 10.1021/acs.jnatprod.2c00484
Plasmodium falciparum Plasmodium falciparum IC50 5.0 nM 10.1021/np3002942
Plasmodium falciparum Plasmodium falciparum IC50 5.0 nM 10.1021/np5007907
Plasmodium falciparum Plasmodium falciparum IC50 5.2 nM 10.1021/ml400311r
Plasmodium falciparum Plasmodium falciparum IC50 5.3 nM 10.1016/j.bmcl.2017.07.039
Plasmodium falciparum Plasmodium falciparum IC50 5.3 nM 10.1021/acs.jnatprod.7b00992
Plasmodium falciparum Plasmodium falciparum IC50 5.35 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 5.4 nM 10.1016/j.bmc.2014.05.024
Plasmodium falciparum Plasmodium falciparum IC50 5.4 nM 10.1016/j.ejmech.2013.01.017
Plasmodium falciparum Plasmodium falciparum IC50 5.4 nM 10.1016/j.ejmech.2013.05.023
Plasmodium falciparum Plasmodium falciparum IC50 5.49 nM 10.1016/j.bmcl.2014.09.088
Plasmodium falciparum Plasmodium falciparum IC50 5.5 nM 10.1021/jm101383f
Plasmodium falciparum Plasmodium falciparum IC50 5.5 nM 10.1021/np500577v
Plasmodium falciparum Plasmodium falciparum IC50 5.6 nM 10.1016/j.bmc.2011.01.030
Plasmodium falciparum Plasmodium falciparum IC50 5.64 nM 10.1128/aac.00527-07
Plasmodium falciparum Plasmodium falciparum IC50 5.7 nM 10.1021/acs.jmedchem.7b00140
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1016/j.bmc.2011.08.033
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1016/j.bmc.2017.06.029
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1016/j.bmcl.2004.10.069
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1016/j.bmcl.2014.12.051
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1016/j.ejmech.2014.04.083
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1016/j.ejmech.2017.09.040
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1021/acs.jmedchem.0c01744
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1021/acs.jnatprod.6b00980
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1021/acs.jnatprod.8b00425
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1021/jm030545e
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1021/jm200227r
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1021/np4007525
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1021/np500390b
Plasmodium falciparum Plasmodium falciparum IC50 6.0 nM 10.1021/np5004164
Plasmodium falciparum Plasmodium falciparum IC50 6.18 nM 10.1021/np980144f
Plasmodium falciparum Plasmodium falciparum IC50 6.25 nM 10.1016/j.bmc.2021.116018
Plasmodium falciparum Plasmodium falciparum IC50 6.3 nM 10.1021/np3002223
Plasmodium falciparum Plasmodium falciparum IC50 6.3 nM 10.6019/CHEMBL2113921
Plasmodium falciparum Plasmodium falciparum IC50 6.4 nM 10.1016/j.ejmech.2018.01.039
Plasmodium falciparum Plasmodium falciparum IC50 6.5 nM 10.1016/j.ejmech.2011.02.004
Plasmodium falciparum Plasmodium falciparum IC50 6.5 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 6.5 nM 10.1021/jm060399n
Plasmodium falciparum Plasmodium falciparum IC50 6.5 nM 10.1021/jm9803828
Plasmodium falciparum Plasmodium falciparum IC50 6.5 nM 10.1128/aac.00638-09
Plasmodium falciparum Plasmodium falciparum IC50 6.57 nM 10.1016/j.bmcl.2014.02.044
Plasmodium falciparum Plasmodium falciparum IC50 6.6 nM 10.1016/j.bmcl.2015.09.033
Plasmodium falciparum Plasmodium falciparum IC50 6.6 nM 10.1021/jm701435h
Plasmodium falciparum Plasmodium falciparum IC50 6.8 nM 10.1021/jm500811p
Plasmodium falciparum Plasmodium falciparum IC50 6.9 nM 10.1016/j.ejmech.2014.11.022
Plasmodium falciparum Plasmodium falciparum IC50 6.9 nM 10.1021/acs.jnatprod.9b01147
Plasmodium falciparum Plasmodium falciparum IC50 6.9 nM 10.1021/jm1006484
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1016/j.bmcl.2013.03.007
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1016/j.ejmech.2017.03.010
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1016/j.ejmech.2018.06.042
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1016/j.ejmech.2018.11.008
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1016/j.ejmech.2020.112969
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1016/j.ejmech.2020.113065
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1021/acs.jnatprod.9b00933
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1021/jm3007596
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1021/jm300802s
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1021/jm801352s
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1021/jm900972u
Plasmodium falciparum Plasmodium falciparum IC50 7.0 nM 10.1021/jm980146x
Plasmodium falciparum Plasmodium falciparum IC50 7.2 nM 10.1016/j.ejmech.2016.07.027
Plasmodium falciparum Plasmodium falciparum IC50 7.2 nM 10.1128/aac.00431-10
Plasmodium falciparum Plasmodium falciparum IC50 7.6 nM 10.1021/acs.jnatprod.8b00643
Plasmodium falciparum Plasmodium falciparum IC50 7.6 nM 10.1021/acs.jnatprod.9b00749
Plasmodium falciparum Plasmodium falciparum IC50 7.68 nM 10.1016/j.bmcl.2012.07.028
Plasmodium falciparum Plasmodium falciparum IC50 7.68 nM 10.1016/j.ejmech.2017.04.063
Plasmodium falciparum Plasmodium falciparum IC50 7.75 nM 10.1016/j.ejmech.2009.09.012
Plasmodium falciparum Plasmodium falciparum IC50 7.8 nM 10.1016/j.bmc.2007.10.083
Plasmodium falciparum Plasmodium falciparum IC50 7.8 nM 10.1016/j.bmcl.2018.03.026
Plasmodium falciparum Plasmodium falciparum IC50 8.0 nM 10.1016/j.bmcl.2020.127037
Plasmodium falciparum Plasmodium falciparum IC50 8.0 nM 10.1021/acs.jmedchem.0c01411
Plasmodium falciparum Plasmodium falciparum IC50 8.0 nM 10.1021/acs.jmedchem.6b00719
Plasmodium falciparum Plasmodium falciparum IC50 8.0 nM 10.1021/acs.jnatprod.7b01041
Plasmodium falciparum Plasmodium falciparum IC50 8.0 nM 10.1021/acs.jnatprod.9b00755
Plasmodium falciparum Plasmodium falciparum IC50 8.0 nM 10.1021/jm8007322
Plasmodium falciparum Plasmodium falciparum IC50 8.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 8.0 nM 10.1039/C7MD00052A
Plasmodium falciparum Plasmodium falciparum IC50 8.1 nM 10.1021/jm701435h
Plasmodium falciparum Plasmodium falciparum IC50 8.15 nM 10.1016/j.bmcl.2009.10.010
Plasmodium falciparum Plasmodium falciparum IC50 8.15 nM 10.1016/j.ejmech.2010.12.003
Plasmodium falciparum Plasmodium falciparum IC50 8.15 nM 10.1039/C9MD00298G
Plasmodium falciparum Plasmodium falciparum IC50 8.2 nM 10.1128/aac.01304-08
Plasmodium falciparum Plasmodium falciparum IC50 8.3 nM 10.1021/np300638f
Plasmodium falciparum Plasmodium falciparum IC50 8.4 nM 10.1016/j.bmc.2009.08.003
Plasmodium falciparum Plasmodium falciparum IC50 8.49 nM 10.1128/aac.00527-07
Plasmodium falciparum Plasmodium falciparum IC50 8.5 nM 10.1016/j.bmcl.2011.04.090
Plasmodium falciparum Plasmodium falciparum IC50 8.5 nM 10.1021/jm030038x
Plasmodium falciparum Plasmodium falciparum IC50 8.6 nM 10.1016/j.ejmech.2014.11.016
Plasmodium falciparum Plasmodium falciparum IC50 8.6 nM 10.1021/acsmedchemlett.9b00457
Plasmodium falciparum Plasmodium falciparum IC50 8.6 nM 10.1128/aac.00544-08
Plasmodium falciparum Plasmodium falciparum IC50 8.7 nM 10.1016/j.bmcl.2011.01.101
Plasmodium falciparum Plasmodium falciparum IC50 8.9 nM 10.1021/jm00089a025
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1016/j.bmc.2015.01.036
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1016/j.bmcl.2016.01.052
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1016/j.bmcl.2023.129258
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1021/acs.jmedchem.1c00483
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1021/acs.jnatprod.6b00967
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1021/acs.jnatprod.7b00543
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1021/acs.jnatprod.7b00650
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1021/acs.jnatprod.8b00154
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1021/acs.jnatprod.9b00932
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1021/jm200463z
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1021/np050315y
Plasmodium falciparum Plasmodium falciparum IC50 9.0 nM 10.1021/np970217f
Plasmodium falciparum Plasmodium falciparum IC50 9.25 nM 10.1021/jm5004528
Plasmodium falciparum Plasmodium falciparum IC50 9.3 nM 10.1016/j.bmcl.2017.03.065
Plasmodium falciparum Plasmodium falciparum IC50 9.3 nM 10.1021/np0105275
Plasmodium falciparum Plasmodium falciparum IC50 9.4 nM 10.1016/j.bmc.2014.03.030
Plasmodium falciparum Plasmodium falciparum IC50 9.4 nM 10.1016/j.ejmech.2013.03.072
Plasmodium falciparum Plasmodium falciparum IC50 9.4 nM 10.1021/jm300887b
Plasmodium falciparum Plasmodium falciparum IC50 9.4 nM 10.1021/np3002223
Plasmodium falciparum Plasmodium falciparum IC50 9.4 nM 10.1039/C4MD00091A
Plasmodium falciparum Plasmodium falciparum IC50 9.4 nM 10.1128/aac.01568-08
Plasmodium falciparum Plasmodium falciparum IC50 9.47 nM 10.1128/aac.01144-06
Plasmodium falciparum Plasmodium falciparum IC50 9.5 nM 10.1021/np050313d
Plasmodium falciparum Plasmodium falciparum IC50 9.6 nM 10.1021/acs.jmedchem.7b01672
Plasmodium falciparum Plasmodium falciparum IC50 9.6 nM 10.1021/acs.jmedchem.8b01961
Plasmodium falciparum Plasmodium falciparum IC50 9.7 nM 10.1016/j.bmc.2011.11.053
Plasmodium falciparum Plasmodium falciparum IC50 9.75 nM 10.1021/jm960370r
Plasmodium falciparum Plasmodium falciparum IC50 9.8 nM 10.1016/j.bmc.2015.07.048
Plasmodium falciparum Plasmodium falciparum IC50 9.8 nM 10.1021/acs.jmedchem.5b01380
Plasmodium falciparum Plasmodium falciparum IC50 9.9 nM 10.1021/jm400004u
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.bmc.2007.10.031
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.bmc.2008.11.009
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.bmc.2014.12.018
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.bmc.2015.07.051
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.bmcl.2016.05.024
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.ejmech.2010.07.068
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.ejmech.2011.08.043
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.ejmech.2014.05.050
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.ejmech.2014.07.105
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.ejmech.2020.113084
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1016/j.ejmech.2021.113518
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/acs.jmedchem.1c00354
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/acs.jmedchem.1c00441
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/acs.jnatprod.7b01019
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/acs.jnatprod.8b00498
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/acsmedchemlett.6b00416
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/acsmedchemlett.9b00457
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/jm0310840
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/jm061429p
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/jm200227r
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/jm301506h
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/jm7012375
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/jm701247k
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/jm801352s
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/jm801490z
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/ml2002136
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/ml300008j
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/ml4001084
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1021/np100737q
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 10.0 nM 10.1039/c9md00468h
Plasmodium falciparum Plasmodium falciparum IC50 10.0 ug.mL-1 10.1007/s00044-012-0328-z
Plasmodium falciparum Plasmodium falciparum IC50 10.1 nM 10.1016/j.bmcl.2006.07.060
Plasmodium falciparum Plasmodium falciparum IC50 10.11 nM 10.1128/aac.01144-06
Plasmodium falciparum Plasmodium falciparum IC50 10.2 nM 10.1016/j.bmc.2013.09.047
Plasmodium falciparum Plasmodium falciparum IC50 10.2 nM 10.1016/j.ejmech.2019.06.069
Plasmodium falciparum Plasmodium falciparum IC50 10.41 nM 10.1128/aac.00057-08
Plasmodium falciparum Plasmodium falciparum IC50 10.6 nM 10.1016/j.bmcl.2014.09.071
Plasmodium falciparum Plasmodium falciparum IC50 10.7 nM 10.1128/aac.01304-08
Plasmodium falciparum Plasmodium falciparum IC50 10.84 nM 10.1021/jm00398a026
Plasmodium falciparum Plasmodium falciparum IC50 10.9 nM 10.1016/j.bmcl.2015.12.080
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1016/j.bmc.2009.10.013
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1016/j.bmc.2014.04.066
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1016/j.bmc.2015.05.055
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1016/j.bmcl.2011.03.104
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1016/j.ejmech.2017.02.024
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1016/j.ejmech.2018.09.018
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1016/j.ejmech.2019.111983
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1016/j.ejmech.2022.114408
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1021/acs.jnatprod.1c00063
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1021/jm200543y
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1021/ml100308d
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1021/ml500211c
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1021/np020070e
Plasmodium falciparum Plasmodium falciparum IC50 11.0 nM 10.1128/aac.00638-09
Plasmodium falciparum Plasmodium falciparum IC50 11.2 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 11.35 nM 10.1016/j.bmcl.2016.05.039
Plasmodium falciparum Plasmodium falciparum IC50 11.57 nM 10.1128/aac.00057-08
Plasmodium falciparum Plasmodium falciparum IC50 11.6 nM 10.1016/j.bmcl.2009.04.100
Plasmodium falciparum Plasmodium falciparum IC50 11.7 nM 10.1021/acs.jmedchem.8b01310
Plasmodium falciparum Plasmodium falciparum IC50 11.81 nM 10.1021/jm500535j
Plasmodium falciparum Plasmodium falciparum IC50 11.81 nM 10.1021/jm500715u
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1016/j.bmc.2014.09.040
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1016/j.bmc.2019.115185
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1016/j.bmcl.2011.05.119
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1016/j.bmcl.2019.126911
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1016/j.ejmech.2012.06.046
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1016/j.ejmech.2021.113330
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1016/s0960-894x(02)00289-5
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1021/acs.jmedchem.5b01374
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1021/acs.jnatprod.9b00589
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1021/jm030084x
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1021/jm200302d
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1021/jm5018303
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1039/C8MD00608C
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1128/aac.00757-07
Plasmodium falciparum Plasmodium falciparum IC50 12.0 nM 10.1128/aac.01220-10
Plasmodium falciparum Plasmodium falciparum IC50 12.07 nM 10.1128/aac.01144-06
Plasmodium falciparum Plasmodium falciparum IC50 12.08 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 12.08 nM 10.1021/jm8006905
Plasmodium falciparum Plasmodium falciparum IC50 12.1 nM 10.1016/j.bmc.2015.06.044
Plasmodium falciparum Plasmodium falciparum IC50 12.27 nM 10.1021/jm100938u
Plasmodium falciparum Plasmodium falciparum IC50 12.27 nM 10.1021/jm500033r
Plasmodium falciparum Plasmodium falciparum IC50 12.3 nM 10.1021/acsmedchemlett.8b00371
Plasmodium falciparum Plasmodium falciparum IC50 12.3 nM 10.1039/C5MD00062A
Plasmodium falciparum Plasmodium falciparum IC50 12.4 nM 10.1016/j.bmc.2008.03.005
Plasmodium falciparum Plasmodium falciparum IC50 12.44 nM 10.1021/jm800737y
Plasmodium falciparum Plasmodium falciparum IC50 12.5 nM 10.1016/j.bmc.2016.06.047
Plasmodium falciparum Plasmodium falciparum IC50 12.5 nM 10.1016/j.ejmech.2015.06.045
Plasmodium falciparum Plasmodium falciparum IC50 12.52 nM 10.1039/C1MD00102G
Plasmodium falciparum Plasmodium falciparum IC50 12.56 nM 10.1021/acsmedchemlett.0c00196
Plasmodium falciparum Plasmodium falciparum IC50 12.6 nM 10.1128/aac.01466-08
Plasmodium falciparum Plasmodium falciparum IC50 12.63 nM 10.1128/aac.01144-06
Plasmodium falciparum Plasmodium falciparum IC50 12.8 nM 10.1021/np200399t
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1016/j.bmc.2006.12.034
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1016/j.bmc.2008.05.079
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1016/j.bmcl.2006.08.009
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1016/j.bmcl.2015.12.032
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1016/j.ejmech.2021.113193
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1021/acs.jnatprod.7b00876
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1021/jm00026a010
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1021/jm9902180
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1039/C4MD00406J
Plasmodium falciparum Plasmodium falciparum IC50 13.0 nM 10.1128/aac.00638-09
Plasmodium falciparum Plasmodium falciparum IC50 13.17 nM 10.1021/jm701417a
Plasmodium falciparum Plasmodium falciparum IC50 13.4 nM 10.1016/j.bmcl.2010.11.099
Plasmodium falciparum Plasmodium falciparum IC50 13.5 nM 10.1016/j.ejmech.2007.11.024
Plasmodium falciparum Plasmodium falciparum IC50 13.5 nM 10.1021/jm800106u
Plasmodium falciparum Plasmodium falciparum IC50 13.5 ug.mL-1 10.1016/j.bmc.2006.10.006
Plasmodium falciparum Plasmodium falciparum IC50 13.5 ug.mL-1 10.1016/j.bmc.2007.10.055
Plasmodium falciparum Plasmodium falciparum IC50 13.7 nM 10.1021/jm050966r
Plasmodium falciparum Plasmodium falciparum IC50 13.72 nM 10.1016/j.bmc.2008.05.017
Plasmodium falciparum Plasmodium falciparum IC50 13.76 nM 10.1021/jm020891g
Plasmodium falciparum Plasmodium falciparum IC50 13.9 nM 10.1021/acs.jmedchem.8b01799
Plasmodium falciparum Plasmodium falciparum IC50 13.9 nM 10.1021/acs.jnatprod.8b00956
Plasmodium falciparum Plasmodium falciparum IC50 14.0 nM 10.1007/s00044-007-9025-8
Plasmodium falciparum Plasmodium falciparum IC50 14.0 nM 10.1016/j.bmc.2022.116830
Plasmodium falciparum Plasmodium falciparum IC50 14.0 nM 10.1016/j.bmcl.2006.11.051
Plasmodium falciparum Plasmodium falciparum IC50 14.0 nM 10.1016/j.bmcl.2014.11.039
Plasmodium falciparum Plasmodium falciparum IC50 14.0 nM 10.1016/j.ejmech.2017.04.016
Plasmodium falciparum Plasmodium falciparum IC50 14.0 nM 10.1016/j.ejmech.2020.113065
Plasmodium falciparum Plasmodium falciparum IC50 14.0 nM 10.1021/acs.jmedchem.0c00131
Plasmodium falciparum Plasmodium falciparum IC50 14.0 nM 10.1021/jm701606b
Plasmodium falciparum Plasmodium falciparum IC50 14.0 nM 10.1021/np000285t
Plasmodium falciparum Plasmodium falciparum IC50 14.0 nM 10.1128/aac.00439-08
Plasmodium falciparum Plasmodium falciparum IC50 14.2 nM 10.1021/jm101383f
Plasmodium falciparum Plasmodium falciparum IC50 14.3 nM 10.1016/j.bmc.2012.07.040
Plasmodium falciparum Plasmodium falciparum IC50 14.3 nM 10.1016/j.bmcl.2019.05.001
Plasmodium falciparum Plasmodium falciparum IC50 14.3 nM 10.1016/j.ejmech.2007.03.008
Plasmodium falciparum Plasmodium falciparum IC50 14.3 nM 10.1016/j.ejmech.2007.11.003
Plasmodium falciparum Plasmodium falciparum IC50 14.3 nM 10.1021/jm010842o
Plasmodium falciparum Plasmodium falciparum IC50 14.5 nM 10.1021/acsmedchemlett.8b00371
Plasmodium falciparum Plasmodium falciparum IC50 14.5 nM 10.1039/C5MD00062A
Plasmodium falciparum Plasmodium falciparum IC50 14.7 nM 10.1021/np200499d
Plasmodium falciparum Plasmodium falciparum IC50 14.7 nM 10.1128/aac.00669-07
Plasmodium falciparum Plasmodium falciparum IC50 14.9 nM 10.1021/jm8012618
Plasmodium falciparum Plasmodium falciparum IC50 14.98 nM 10.1021/jm030796n
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1007/s00044-008-9092-5
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1016/j.bmc.2009.02.050
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1016/j.bmc.2015.02.061
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1016/j.bmcl.2008.05.068
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1016/j.bmcl.2010.06.007
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1021/acs.jmedchem.0c00539
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1021/acs.jmedchem.1c00748
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1021/acs.jmedchem.8b01961
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1021/jm400938g
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1021/jm501809x
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1021/jm7009292
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1021/ml400447v
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.1039/C4MD00454J
Plasmodium falciparum Plasmodium falciparum IC50 15.0 nM 10.6019/CHEMBL2113921
Plasmodium falciparum Plasmodium falciparum IC50 15.62 nM 10.1016/j.bmcl.2009.02.013
Plasmodium falciparum Plasmodium falciparum IC50 15.7 nM 10.1128/aac.01412-09
Plasmodium falciparum Plasmodium falciparum IC50 15.9 nM 10.1016/j.ejmech.2015.03.045
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1016/j.bmc.2010.05.054
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1016/j.bmc.2011.10.044
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1016/j.bmcl.2013.12.067
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1016/j.bmcl.2014.06.012
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1016/j.ejmech.2012.01.039
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1016/j.ejmech.2014.09.060
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1016/j.ejmech.2018.09.060
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1016/j.ejmech.2021.113518
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/acs.jmedchem.5b01156
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/acs.jmedchem.5b01605
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/acs.jmedchem.6b01265
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/acs.jmedchem.6b01685
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/acs.jmedchem.8b00382
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/acs.jmedchem.8b01333
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/acs.jmedchem.8b01769
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/jm201108k
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/jm201676t
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/jm500098s
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1021/jm800106u
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1039/C5MD00343A
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1039/C7MD00063D
Plasmodium falciparum Plasmodium falciparum IC50 16.0 nM 10.1128/aac.00544-08
Plasmodium falciparum Plasmodium falciparum IC50 16.11 nM 10.1016/j.ejmech.2019.05.043
Plasmodium falciparum Plasmodium falciparum IC50 16.3 nM 10.1021/acs.jmedchem.0c01744
Plasmodium falciparum Plasmodium falciparum IC50 16.48 nM 10.1128/aac.01479-06
Plasmodium falciparum Plasmodium falciparum IC50 16.5 nM 10.1021/jm030181q
Plasmodium falciparum Plasmodium falciparum IC50 16.6 nM 10.1016/j.bmcl.2021.128196
Plasmodium falciparum Plasmodium falciparum IC50 16.7 nM 10.1128/aac.01656-08
Plasmodium falciparum Plasmodium falciparum IC50 16.9 nM 10.1016/j.bmcl.2009.04.100
Plasmodium falciparum Plasmodium falciparum IC50 16.92 nM 10.1016/j.bmc.2012.07.041
Plasmodium falciparum Plasmodium falciparum IC50 17.0 nM 10.1016/j.bmc.2010.10.009
Plasmodium falciparum Plasmodium falciparum IC50 17.0 nM 10.1016/j.bmcl.2004.01.083
Plasmodium falciparum Plasmodium falciparum IC50 17.0 nM 10.1016/j.bmcl.2014.12.037
Plasmodium falciparum Plasmodium falciparum IC50 17.0 nM 10.1016/j.bmcl.2015.01.003
Plasmodium falciparum Plasmodium falciparum IC50 17.0 nM 10.1021/acs.jmedchem.7b00140
Plasmodium falciparum Plasmodium falciparum IC50 17.0 nM 10.1021/jm0600951
Plasmodium falciparum Plasmodium falciparum IC50 17.0 nM 10.1021/jm100057h
Plasmodium falciparum Plasmodium falciparum IC50 17.0 nM 10.1021/jm200149e
Plasmodium falciparum Plasmodium falciparum IC50 17.0 nM 10.1021/jm300588j
Plasmodium falciparum Plasmodium falciparum IC50 17.0 nM 10.1021/jm301893b
Plasmodium falciparum Plasmodium falciparum IC50 17.0 nM 10.1021/jm9002632
Plasmodium falciparum Plasmodium falciparum IC50 17.09 nM 10.1021/jm500535j
Plasmodium falciparum Plasmodium falciparum IC50 17.1 nM 10.1021/jm500715u
Plasmodium falciparum Plasmodium falciparum IC50 17.3 nM 10.1021/jm501439w
Plasmodium falciparum Plasmodium falciparum IC50 17.4 nM 10.1016/j.ejmech.2013.08.046
Plasmodium falciparum Plasmodium falciparum IC50 17.45 ppm 10.1016/j.bmc.2019.06.038
Plasmodium falciparum Plasmodium falciparum IC50 17.45 ppm 10.1016/j.ejmech.2017.02.012
Plasmodium falciparum Plasmodium falciparum IC50 17.63 nM 10.1021/jm070684m
Plasmodium falciparum Plasmodium falciparum IC50 17.7 nM 10.1016/j.bmcl.2011.05.131
Plasmodium falciparum Plasmodium falciparum IC50 17.8 nM 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum IC50 18.0 nM 10.1016/j.bmc.2007.02.022
Plasmodium falciparum Plasmodium falciparum IC50 18.0 nM 10.1016/j.bmc.2009.10.005
Plasmodium falciparum Plasmodium falciparum IC50 18.0 nM 10.1016/j.bmcl.2004.05.026
Plasmodium falciparum Plasmodium falciparum IC50 18.0 nM 10.1016/j.bmcl.2005.03.050
Plasmodium falciparum Plasmodium falciparum IC50 18.0 nM 10.1016/j.bmcl.2012.05.064
Plasmodium falciparum Plasmodium falciparum IC50 18.0 nM 10.1016/j.bmcl.2013.08.077
Plasmodium falciparum Plasmodium falciparum IC50 18.0 nM 10.1016/j.ejmech.2015.02.047
Plasmodium falciparum Plasmodium falciparum IC50 18.0 nM 10.1016/j.ejmech.2018.01.039
Plasmodium falciparum Plasmodium falciparum IC50 18.0 nM 10.1016/j.ejmech.2018.02.021
Plasmodium falciparum Plasmodium falciparum IC50 18.0 nM 10.1021/jm010374i
Plasmodium falciparum Plasmodium falciparum IC50 18.0 nM 10.1039/C1MD00022E
Plasmodium falciparum Plasmodium falciparum IC50 18.5 nM 10.1016/j.ejmech.2015.06.024
Plasmodium falciparum Plasmodium falciparum IC50 18.5 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 18.5 nM 10.1128/aac.00610-09
Plasmodium falciparum Plasmodium falciparum IC50 18.9 ug.mL-1 10.1016/j.ejmech.2015.02.040
Plasmodium falciparum Plasmodium falciparum IC50 19.0 nM 10.1016/j.bmc.2018.06.037
Plasmodium falciparum Plasmodium falciparum IC50 19.0 nM 10.1016/j.ejmech.2009.02.024
Plasmodium falciparum Plasmodium falciparum IC50 19.0 nM 10.1021/acs.jmedchem.0c00960
Plasmodium falciparum Plasmodium falciparum IC50 19.0 nM 10.1021/acs.jmedchem.0c01480
Plasmodium falciparum Plasmodium falciparum IC50 19.0 nM 10.1021/jm001096a
Plasmodium falciparum Plasmodium falciparum IC50 19.0 nM 10.1021/jm0108707
Plasmodium falciparum Plasmodium falciparum IC50 19.0 nM 10.1021/jm9901374
Plasmodium falciparum Plasmodium falciparum IC50 19.0 nM 10.1021/ml100120a
Plasmodium falciparum Plasmodium falciparum IC50 19.0 nM 10.1128/aac.00669-07
Plasmodium falciparum Plasmodium falciparum IC50 19.4 nM 10.1021/jm8012618
Plasmodium falciparum Plasmodium falciparum IC50 19.5 nM 10.1016/j.bmc.2008.09.038
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1007/s00044-008-9089-0
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/0960-894X(95)00326-O
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/0960-894X(96)00040-6
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmc.2011.07.009
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmc.2011.10.037
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmc.2014.09.040
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmc.2014.11.028
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmc.2014.12.018
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmc.2016.06.003
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmc.2019.06.038
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmcl.2003.12.069
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmcl.2005.01.011
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmcl.2006.11.013
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmcl.2007.06.070
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmcl.2010.11.081
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmcl.2012.10.126
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.bmcl.2021.128442
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.ejmech.2013.08.004
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.ejmech.2016.12.041
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.ejmech.2019.111983
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1016/s0960-894x(01)00798-3
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/acs.jnatprod.5b00114
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/acsmedchemlett.8b00592
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/jm030974c
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/jm0492608
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/jm200686d
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/jm9604944
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/jm990946n
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/ml2002136
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/np000285t
Plasmodium falciparum Plasmodium falciparum IC50 20.0 nM 10.1021/np100737q
Plasmodium falciparum Plasmodium falciparum IC50 20.2 nM 10.1021/jm8012757
Plasmodium falciparum Plasmodium falciparum IC50 20.4 nM 10.1016/j.ejmech.2018.11.021
Plasmodium falciparum Plasmodium falciparum IC50 21.0 nM 10.1016/j.bmcl.2005.11.060
Plasmodium falciparum Plasmodium falciparum IC50 21.0 nM 10.1016/j.ejmech.2014.12.020
Plasmodium falciparum Plasmodium falciparum IC50 21.0 nM 10.1016/j.ejmech.2018.10.035
Plasmodium falciparum Plasmodium falciparum IC50 21.0 nM 10.1021/acs.jmedchem.5b00678
Plasmodium falciparum Plasmodium falciparum IC50 21.0 nM 10.1021/acs.jmedchem.6b00719
Plasmodium falciparum Plasmodium falciparum IC50 21.0 nM 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum IC50 21.0 nM 10.1021/jm020960r
Plasmodium falciparum Plasmodium falciparum IC50 21.0 nM 10.1128/aac.00638-09
Plasmodium falciparum Plasmodium falciparum IC50 21.0 nM 10.1128/aac.01392-07
Plasmodium falciparum Plasmodium falciparum IC50 21.0 ug.mL-1 10.1021/np050315y
Plasmodium falciparum Plasmodium falciparum IC50 21.3 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 21.5 nM 10.1016/j.ejmech.2018.10.041
Plasmodium falciparum Plasmodium falciparum IC50 21.54 nM 10.1016/j.bmcl.2010.09.130
Plasmodium falciparum Plasmodium falciparum IC50 21.54 nM 10.1016/j.bmcl.2011.01.103
Plasmodium falciparum Plasmodium falciparum IC50 21.55 nM 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Plasmodium falciparum IC50 21.8 nM 10.1021/jm060259d
Plasmodium falciparum Plasmodium falciparum IC50 21.9 nM 10.1021/acs.jnatprod.2c01041
Plasmodium falciparum Plasmodium falciparum IC50 22.0 nM 10.1016/j.ejmech.2021.113227
Plasmodium falciparum Plasmodium falciparum IC50 22.0 nM 10.1021/jm061429p
Plasmodium falciparum Plasmodium falciparum IC50 22.0 nM 10.1021/jm101642g
Plasmodium falciparum Plasmodium falciparum IC50 22.0 nM 10.1021/jm300802s
Plasmodium falciparum Plasmodium falciparum IC50 22.0 nM 10.1021/jm701247k
Plasmodium falciparum Plasmodium falciparum IC50 22.0 nM 10.1021/jm801352s
Plasmodium falciparum Plasmodium falciparum IC50 22.0 nM 10.1021/jm990946n
Plasmodium falciparum Plasmodium falciparum IC50 22.0 nM 10.1021/np020008h
Plasmodium falciparum Plasmodium falciparum IC50 22.0 nM 10.1128/aac.00431-10
Plasmodium falciparum Plasmodium falciparum IC50 22.5 nM 10.1016/j.bmcl.2006.07.060
Plasmodium falciparum Plasmodium falciparum IC50 22.76 nM 10.1128/aac.01479-06
Plasmodium falciparum Plasmodium falciparum IC50 22.9 nM 10.1016/j.bmc.2007.07.012
Plasmodium falciparum Plasmodium falciparum IC50 22.9 nM 10.1016/j.bmcl.2009.12.030
Plasmodium falciparum Plasmodium falciparum IC50 22.9 nM 10.1128/aac.01656-08
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1016/j.bmc.2010.09.005
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1016/j.bmc.2015.02.007
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1016/j.bmcl.2006.01.009
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1016/j.bmcl.2007.07.049
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1016/j.bmcl.2012.07.069
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1016/j.bmcl.2019.06.045
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1016/j.bmcl.2021.127855
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1016/j.ejmech.2016.02.056
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1021/acs.jmedchem.0c01480
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1021/acs.jnatprod.7b00587
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1021/jm2009698
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1021/jm3000328
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.1039/C5MD00115C
Plasmodium falciparum Plasmodium falciparum IC50 23.0 nM 10.6019/CHEMBL2113921
Plasmodium falciparum Plasmodium falciparum IC50 23.37 nM 10.1128/aac.01479-06
Plasmodium falciparum Plasmodium falciparum IC50 23.4 nM 10.1021/acsmedchemlett.9b00457
Plasmodium falciparum Plasmodium falciparum IC50 23.5 nM 10.1021/np900853n
Plasmodium falciparum Plasmodium falciparum IC50 23.66 nM 10.1016/j.bmcl.2011.05.119
Plasmodium falciparum Plasmodium falciparum IC50 23.7 nM 10.1021/acs.jmedchem.0c00033
Plasmodium falciparum Plasmodium falciparum IC50 23.72 nM 10.1016/j.bmc.2012.07.041
Plasmodium falciparum Plasmodium falciparum IC50 23.9 nM 10.1016/j.bmcl.2007.10.003
Plasmodium falciparum Plasmodium falciparum IC50 23.9 nM 10.1016/j.ejmech.2021.113981
Plasmodium falciparum Plasmodium falciparum IC50 24.0 nM 10.1021/ml200135p
Plasmodium falciparum Plasmodium falciparum IC50 24.0 nM 10.1021/ml2001517
Plasmodium falciparum Plasmodium falciparum IC50 24.0 nM 10.1021/np0105275
Plasmodium falciparum Plasmodium falciparum IC50 24.7 nM 10.1128/aac.00536-09
Plasmodium falciparum Plasmodium falciparum IC50 24.8 nM 10.1016/j.bmc.2010.08.001
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1016/j.ejmech.2009.02.024
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1016/j.ejmech.2011.02.029
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1021/acs.jnatprod.0c00929
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1021/jm3002795
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1021/np9002564
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1021/np900834g
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1021/np970217f
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1128/aac.00967-06
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1128/aac.01392-07
Plasmodium falciparum Plasmodium falciparum IC50 25.0 nM 10.1128/aac.01462-08
Plasmodium falciparum Plasmodium falciparum IC50 25.5 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 25.6 nM 10.1016/j.bmcl.2016.11.077
Plasmodium falciparum Plasmodium falciparum IC50 26.0 nM 10.1016/j.ejmech.2018.03.024
Plasmodium falciparum Plasmodium falciparum IC50 26.0 nM 10.1016/j.ejmech.2018.08.063
Plasmodium falciparum Plasmodium falciparum IC50 26.0 nM 10.1021/np100196b
Plasmodium falciparum Plasmodium falciparum IC50 26.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 26.0 nM 10.1128/aac.01392-07
Plasmodium falciparum Plasmodium falciparum IC50 27.0 nM 10.1016/j.bmc.2011.06.025
Plasmodium falciparum Plasmodium falciparum IC50 27.0 nM 10.1016/j.ejmech.2019.111983
Plasmodium falciparum Plasmodium falciparum IC50 27.0 nM 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum IC50 27.0 nM 10.1021/acsmedchemlett.8b00496
Plasmodium falciparum Plasmodium falciparum IC50 27.0 nM 10.1021/jm00035a017
Plasmodium falciparum Plasmodium falciparum IC50 27.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 27.2 nM 10.1016/j.bmc.2008.05.068
Plasmodium falciparum Plasmodium falciparum IC50 27.2 nM 10.1016/j.ejmech.2007.09.014
Plasmodium falciparum Plasmodium falciparum IC50 28.0 nM 10.1021/acs.jmedchem.1c00441
Plasmodium falciparum Plasmodium falciparum IC50 28.0 nM 10.1021/acsmedchemlett.1c00354
Plasmodium falciparum Plasmodium falciparum IC50 28.0 nM 10.1021/np0780093
Plasmodium falciparum Plasmodium falciparum IC50 29.0 nM 10.1021/acs.jmedchem.8b00143
Plasmodium falciparum Plasmodium falciparum IC50 29.0 nM 10.1021/jm201056j
Plasmodium falciparum Plasmodium falciparum IC50 29.0 nM 10.1128/aac.01175-08
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.bmc.2010.11.014
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.bmc.2011.12.037
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.bmc.2012.06.038
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.bmcl.2004.05.063
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.bmcl.2005.01.011
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.bmcl.2012.12.029
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.bmcl.2013.08.108
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.bmcl.2013.09.015
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.bmcl.2016.09.038
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.bmcl.2017.02.049
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.ejmech.2009.03.041
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.ejmech.2010.11.037
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.ejmech.2013.03.018
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.ejmech.2014.11.022
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.ejmech.2017.10.010
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1016/j.ejmech.2020.112941
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1021/acs.jnatprod.2c00684
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1021/acs.jnatprod.5b01054
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1021/jm0305319
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1021/np0101705
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1021/np100325q
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1021/np200940b
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1039/C3MD20377H
Plasmodium falciparum Plasmodium falciparum IC50 30.0 nM 10.1128/aac.01469-08
Plasmodium falciparum Plasmodium falciparum IC50 30.2 nM 10.1128/aac.01220-10
Plasmodium falciparum Plasmodium falciparum IC50 30.6 nM 10.1016/j.bmcl.2011.03.090
Plasmodium falciparum Plasmodium falciparum IC50 30.8 nM 10.1021/jm8012757
Plasmodium falciparum Plasmodium falciparum IC50 31.0 nM 10.1021/jm4004279
Plasmodium falciparum Plasmodium falciparum IC50 31.0 nM 10.1128/aac.01392-07
Plasmodium falciparum Plasmodium falciparum IC50 31.92 nM 10.1021/acsmedchemlett.1c00031
Plasmodium falciparum Plasmodium falciparum IC50 32.0 nM 10.1016/j.bmc.2012.05.061
Plasmodium falciparum Plasmodium falciparum IC50 32.0 nM 10.1021/np020070e
Plasmodium falciparum Plasmodium falciparum IC50 32.0 nM 10.1128/aac.01392-07
Plasmodium falciparum Plasmodium falciparum IC50 33.0 nM 10.1016/j.ejmech.2009.02.024
Plasmodium falciparum Plasmodium falciparum IC50 33.4 nM 10.1016/j.bmc.2011.11.053
Plasmodium falciparum Plasmodium falciparum IC50 34.0 nM 10.1016/j.ejmech.2019.111755
Plasmodium falciparum Plasmodium falciparum IC50 34.0 nM 10.1021/acs.jmedchem.0c00539
Plasmodium falciparum Plasmodium falciparum IC50 34.6 nM 10.1128/aac.00801-10
Plasmodium falciparum Plasmodium falciparum IC50 35.0 nM 10.1016/j.ejmech.2013.05.046
Plasmodium falciparum Plasmodium falciparum IC50 35.0 nM 10.1016/j.ejmech.2014.10.061
Plasmodium falciparum Plasmodium falciparum IC50 35.0 nM 10.1021/jm031132g
Plasmodium falciparum Plasmodium falciparum IC50 35.0 nM 10.1021/jm901300d
Plasmodium falciparum Plasmodium falciparum IC50 36.0 nM 10.1016/j.bmc.2013.06.067
Plasmodium falciparum Plasmodium falciparum IC50 36.0 nM 10.1016/j.bmcl.2016.11.077
Plasmodium falciparum Plasmodium falciparum IC50 36.0 nM 10.1016/j.ejmech.2017.04.016
Plasmodium falciparum Plasmodium falciparum IC50 36.0 nM 10.1016/s0960-894x(02)00173-7
Plasmodium falciparum Plasmodium falciparum IC50 36.0 nM 10.1021/acs.jmedchem.5b00114
Plasmodium falciparum Plasmodium falciparum IC50 36.0 nM 10.1021/ml400311r
Plasmodium falciparum Plasmodium falciparum IC50 36.0 nM 10.1128/aac.00951-09
Plasmodium falciparum Plasmodium falciparum IC50 36.1 nM 10.1128/aac.01334-07
Plasmodium falciparum Plasmodium falciparum IC50 36.11 nM 10.1016/j.ejmech.2012.07.037
Plasmodium falciparum Plasmodium falciparum IC50 36.2 nM 10.1021/jm5004528
Plasmodium falciparum Plasmodium falciparum IC50 36.37 nM 10.1016/j.ejmech.2014.07.064
Plasmodium falciparum Plasmodium falciparum IC50 36.9 nM 10.1128/aac.01334-07
Plasmodium falciparum Plasmodium falciparum IC50 38.0 nM 10.1016/j.bmcl.2009.12.062
Plasmodium falciparum Plasmodium falciparum IC50 38.0 nM 10.1021/acs.jmedchem.8b01972
Plasmodium falciparum Plasmodium falciparum IC50 38.0 nM 10.1021/jm990437l
Plasmodium falciparum Plasmodium falciparum IC50 39.0 nM 10.1021/jm7012375
Plasmodium falciparum Plasmodium falciparum IC50 39.0 nM 10.1021/jm990946n
Plasmodium falciparum Plasmodium falciparum IC50 39.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.bmc.2010.05.023
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.bmc.2010.06.066
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.bmc.2012.07.036
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.bmc.2012.09.052
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.bmc.2012.10.019
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.bmcl.2008.08.043
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.bmcl.2012.10.094
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.ejmech.2010.08.049
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.ejmech.2015.03.011
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.ejmech.2017.03.007
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.ejmech.2018.06.025
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.ejmech.2018.10.035
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/j.ejmech.2019.01.047
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/s0960-894x(01)00383-3
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1016/s0960-894x(03)00509-2
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1021/acs.jnatprod.1c00870
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1021/jm201216y
Plasmodium falciparum Plasmodium falciparum IC50 40.0 nM 10.1021/ml3000808
Plasmodium falciparum Plasmodium falciparum IC50 40.0 ug.mL-1 10.1016/j.bmc.2014.01.036
Plasmodium falciparum Plasmodium falciparum IC50 41.0 nM 10.1021/acs.jnatprod.6b00758
Plasmodium falciparum Plasmodium falciparum IC50 41.0 nM 10.1021/jm200227r
Plasmodium falciparum Plasmodium falciparum IC50 41.0 nM 10.1021/np0104626
Plasmodium falciparum Plasmodium falciparum IC50 41.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 41.0 nM 10.1128/aac.00638-09
Plasmodium falciparum Plasmodium falciparum IC50 41.6 nM 10.1016/j.bmc.2009.10.019
Plasmodium falciparum Plasmodium falciparum IC50 41.6 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 41.6 nM 10.1128/aac.00555-07
Plasmodium falciparum Plasmodium falciparum IC50 41.7 nM 10.1016/j.bmcl.2020.127037
Plasmodium falciparum Plasmodium falciparum IC50 42.0 nM 10.1016/j.bmcl.2009.10.106
Plasmodium falciparum Plasmodium falciparum IC50 42.0 nM 10.1016/j.ejmech.2011.04.002
Plasmodium falciparum Plasmodium falciparum IC50 42.0 ug.mL-1 10.1021/np050315y
Plasmodium falciparum Plasmodium falciparum IC50 42.4 nM 10.1016/j.bmc.2011.01.030
Plasmodium falciparum Plasmodium falciparum IC50 43.6 nM 10.1128/aac.00801-10
Plasmodium falciparum Plasmodium falciparum IC50 45.2 nM 10.1128/aac.00527-07
Plasmodium falciparum Plasmodium falciparum IC50 45.2 nM 10.1128/aac.01656-08
Plasmodium falciparum Plasmodium falciparum IC50 45.5 nM 10.1021/acs.jnatprod.5b00581
Plasmodium falciparum Plasmodium falciparum IC50 45.8 nM 10.1016/j.bmc.2011.11.053
Plasmodium falciparum Plasmodium falciparum IC50 46.0 nM 10.1016/j.ejmech.2010.03.006
Plasmodium falciparum Plasmodium falciparum IC50 46.0 nM 10.1021/acs.jnatprod.6b00759
Plasmodium falciparum Plasmodium falciparum IC50 46.0 nM 10.1021/acs.jnatprod.9b00721
Plasmodium falciparum Plasmodium falciparum IC50 46.0 nM 10.1021/acsmedchemlett.8b00222
Plasmodium falciparum Plasmodium falciparum IC50 46.64 nM 10.1016/j.bmc.2012.06.014
Plasmodium falciparum Plasmodium falciparum IC50 47.16 nM 10.1016/j.ejmech.2021.113193
Plasmodium falciparum Plasmodium falciparum IC50 47.47 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 47.8 nM 10.1128/aac.01412-09
Plasmodium falciparum Plasmodium falciparum IC50 48.0 nM 10.1016/j.ejmech.2016.11.057
Plasmodium falciparum Plasmodium falciparum IC50 48.0 nM 10.1021/jm300831b
Plasmodium falciparum Plasmodium falciparum IC50 48.0 nM 10.1128/aac.00669-07
Plasmodium falciparum Plasmodium falciparum IC50 48.52 nM 10.1128/aac.01479-06
Plasmodium falciparum Plasmodium falciparum IC50 49.0 nM 10.1016/j.bmc.2015.07.051
Plasmodium falciparum Plasmodium falciparum IC50 49.0 nM 10.1016/j.bmcl.2012.06.010
Plasmodium falciparum Plasmodium falciparum IC50 49.0 nM 10.1016/j.ejmech.2018.09.018
Plasmodium falciparum Plasmodium falciparum IC50 49.0 nM 10.1021/acsmedchemlett.2c00531
Plasmodium falciparum Plasmodium falciparum IC50 49.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1007/s00044-010-9325-2
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1016/j.bmc.2009.06.020
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1016/j.bmc.2009.09.026
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1016/j.bmc.2013.12.032
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1016/j.bmcl.2007.12.069
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1016/j.bmcl.2009.01.103
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1016/j.ejmech.2020.113084
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1021/acs.jnatprod.9b01247
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1021/jm060899g
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1021/ml400164t
Plasmodium falciparum Plasmodium falciparum IC50 50.0 nM 10.1021/np0580558
Plasmodium falciparum Plasmodium falciparum IC50 50.4 nM 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum IC50 50.5 nM 10.1016/j.ejmech.2010.07.068
Plasmodium falciparum Plasmodium falciparum IC50 50.5 nM 10.1016/j.ejmech.2015.02.011
Plasmodium falciparum Plasmodium falciparum IC50 51.0 nM 10.1016/j.bmcl.2009.05.017
Plasmodium falciparum Plasmodium falciparum IC50 51.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 51.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 51.0 nM 10.1128/aac.00431-10
Plasmodium falciparum Plasmodium falciparum IC50 51.1 nM 10.1016/j.bmcl.2009.04.100
Plasmodium falciparum Plasmodium falciparum IC50 51.1 nM 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum IC50 51.2 nM 10.1021/np034033e
Plasmodium falciparum Plasmodium falciparum IC50 51.9 nM 10.1016/j.bmcl.2015.12.080
Plasmodium falciparum Plasmodium falciparum IC50 52.0 nM 10.1016/j.bmcl.2009.05.017
Plasmodium falciparum Plasmodium falciparum IC50 52.0 nM 10.1021/jm400246e
Plasmodium falciparum Plasmodium falciparum IC50 52.45 nM 10.1021/jm301654b
Plasmodium falciparum Plasmodium falciparum IC50 52.7 nM 10.1128/aac.01656-08
Plasmodium falciparum Plasmodium falciparum IC50 53.0 nM 10.1016/j.bmcl.2012.11.004
Plasmodium falciparum Plasmodium falciparum IC50 53.0 nM 10.1016/j.ejmech.2021.113271
Plasmodium falciparum Plasmodium falciparum IC50 53.0 nM 10.1021/jm901112f
Plasmodium falciparum Plasmodium falciparum IC50 54.0 nM 10.1021/acsmedchemlett.9b00123
Plasmodium falciparum Plasmodium falciparum IC50 54.0 nM 10.1021/jm001096a
Plasmodium falciparum Plasmodium falciparum IC50 54.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 54.0 nM 10.1128/aac.00638-09
Plasmodium falciparum Plasmodium falciparum IC50 54.5 nM 10.1016/j.ejmech.2021.113685
Plasmodium falciparum Plasmodium falciparum IC50 55.0 nM 10.1021/acs.jmedchem.9b00504
Plasmodium falciparum Plasmodium falciparum IC50 55.0 nM 10.1021/jm061464w
Plasmodium falciparum Plasmodium falciparum IC50 55.9 nM 10.1128/aac.01334-07
Plasmodium falciparum Plasmodium falciparum IC50 56.0 nM 10.1128/aac.00325-10
Plasmodium falciparum Plasmodium falciparum IC50 56.3 nM 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum IC50 57.0 nM 10.1128/aac.00638-09
Plasmodium falciparum Plasmodium falciparum IC50 59.0 nM 10.1016/j.bmc.2013.06.067
Plasmodium falciparum Plasmodium falciparum IC50 59.0 nM 10.1016/j.bmc.2014.12.018
Plasmodium falciparum Plasmodium falciparum IC50 59.0 nM 10.1016/j.ejmech.2007.01.001
Plasmodium falciparum Plasmodium falciparum IC50 59.0 nM 10.1021/jm058208o
Plasmodium falciparum Plasmodium falciparum IC50 59.0 nM 10.1021/ml400311r
Plasmodium falciparum Plasmodium falciparum IC50 59.09 nM 10.1016/j.ejmech.2013.10.079
Plasmodium falciparum Plasmodium falciparum IC50 59.3 nM 10.1021/jm8012757
Plasmodium falciparum Plasmodium falciparum IC50 60.0 nM 10.1016/j.bmcl.2013.12.109
Plasmodium falciparum Plasmodium falciparum IC50 60.0 nM 10.1016/j.ejmech.2016.05.069
Plasmodium falciparum Plasmodium falciparum IC50 60.0 nM 10.1016/j.ejmech.2020.112215
Plasmodium falciparum Plasmodium falciparum IC50 60.0 nM 10.1021/acs.jnatprod.1c00143
Plasmodium falciparum Plasmodium falciparum IC50 60.0 nM 10.1021/np050484i
Plasmodium falciparum Plasmodium falciparum IC50 60.0 nM 10.1021/np8000909
Plasmodium falciparum Plasmodium falciparum IC50 60.0 nM 10.1128/aac.00967-06
Plasmodium falciparum Plasmodium falciparum IC50 60.6 nM 10.1128/aac.00801-10
Plasmodium falciparum Plasmodium falciparum IC50 61.8 nM 10.1021/jm060259d
Plasmodium falciparum Plasmodium falciparum IC50 61.8 nM 10.1128/aac.01412-09
Plasmodium falciparum Plasmodium falciparum IC50 62.0 nM 10.1016/j.ejmech.2016.02.016
Plasmodium falciparum Plasmodium falciparum IC50 62.0 nM 10.1021/jm400938g
Plasmodium falciparum Plasmodium falciparum IC50 62.0 nM 10.1039/C1MD00129A
Plasmodium falciparum Plasmodium falciparum IC50 63.0 nM 10.1016/j.bmc.2017.05.054
Plasmodium falciparum Plasmodium falciparum IC50 63.0 nM 10.1016/j.bmc.2017.07.057
Plasmodium falciparum Plasmodium falciparum IC50 63.0 nM 10.1021/acs.jmedchem.7b00140
Plasmodium falciparum Plasmodium falciparum IC50 63.0 nM 10.1021/acs.jnatprod.7b00917
Plasmodium falciparum Plasmodium falciparum IC50 63.2 nM 10.1128/aac.01220-10
Plasmodium falciparum Plasmodium falciparum IC50 64.0 nM 10.1016/j.ejmech.2014.09.060
Plasmodium falciparum Plasmodium falciparum IC50 64.2 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 64.7 nM 10.1021/jm5004528
Plasmodium falciparum Plasmodium falciparum IC50 65.0 nM 10.1016/j.bmcl.2009.04.100
Plasmodium falciparum Plasmodium falciparum IC50 65.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 66.9 nM 10.1016/j.bmcl.2012.02.045
Plasmodium falciparum Plasmodium falciparum IC50 67.0 nM 10.1021/acs.jmedchem.1c00441
Plasmodium falciparum Plasmodium falciparum IC50 68.0 nM 10.1038/nchembio.87
Plasmodium falciparum Plasmodium falciparum IC50 69.0 nM 10.1016/j.bmc.2010.10.009
Plasmodium falciparum Plasmodium falciparum IC50 69.0 nM 10.1016/j.bmcl.2009.12.062
Plasmodium falciparum Plasmodium falciparum IC50 69.0 nM 10.1016/j.ejmech.2018.06.063
Plasmodium falciparum Plasmodium falciparum IC50 69.0 nM 10.1021/jm200149e
Plasmodium falciparum Plasmodium falciparum IC50 69.4 nM 10.1016/j.bmcl.2011.02.008
Plasmodium falciparum Plasmodium falciparum IC50 70.0 nM 10.1016/j.bmc.2015.01.036
Plasmodium falciparum Plasmodium falciparum IC50 70.0 nM 10.1016/j.bmcl.2009.07.095
Plasmodium falciparum Plasmodium falciparum IC50 70.0 nM 10.1016/j.ejmech.2017.11.075
Plasmodium falciparum Plasmodium falciparum IC50 70.0 nM 10.1021/jm0705760
Plasmodium falciparum Plasmodium falciparum IC50 70.0 nM 10.1021/jm200463z
Plasmodium falciparum Plasmodium falciparum IC50 70.0 nM 10.1021/jm900946n
Plasmodium falciparum Plasmodium falciparum IC50 70.0 nM 10.1021/np060007f
Plasmodium falciparum Plasmodium falciparum IC50 70.0 nM 10.1128/aac.01392-07
Plasmodium falciparum Plasmodium falciparum IC50 70.1 nM 10.1016/j.ejmech.2014.11.016
Plasmodium falciparum Plasmodium falciparum IC50 71.0 nM 10.1016/j.bmcl.2016.04.053
Plasmodium falciparum Plasmodium falciparum IC50 71.0 nM 10.1021/np5007907
Plasmodium falciparum Plasmodium falciparum IC50 71.08 nM 10.1016/j.bmc.2016.04.021
Plasmodium falciparum Plasmodium falciparum IC50 71.2 nM 10.1016/j.bmcl.2010.11.099
Plasmodium falciparum Plasmodium falciparum IC50 72.0 nM 10.1016/j.bmc.2013.07.002
Plasmodium falciparum Plasmodium falciparum IC50 72.0 nM 10.1016/j.ejmech.2015.12.045
Plasmodium falciparum Plasmodium falciparum IC50 72.0 nM 10.1021/acsmedchemlett.9b00669
Plasmodium falciparum Plasmodium falciparum IC50 72.0 nM 10.1021/jm701435h
Plasmodium falciparum Plasmodium falciparum IC50 72.0 nM 10.1039/C2MD20197F
Plasmodium falciparum Plasmodium falciparum IC50 72.0 nM 10.1039/C3MD00065F
Plasmodium falciparum Plasmodium falciparum IC50 72.0 nM 10.1128/aac.00638-09
Plasmodium falciparum Plasmodium falciparum IC50 73.9 nM 10.1021/jm701435h
Plasmodium falciparum Plasmodium falciparum IC50 73.97 nM 10.1128/aac.00312-09
Plasmodium falciparum Plasmodium falciparum IC50 75.0 nM 10.1016/j.bmcl.2019.126810
Plasmodium falciparum Plasmodium falciparum IC50 75.0 nM 10.1128/aac.01677-08
Plasmodium falciparum Plasmodium falciparum IC50 75.9 nM 10.1016/j.ejmech.2021.113981
Plasmodium falciparum Plasmodium falciparum IC50 76.0 nM 10.1016/j.ejmech.2012.05.022
Plasmodium falciparum Plasmodium falciparum IC50 76.0 nM 10.1016/j.ejmech.2015.02.047
Plasmodium falciparum Plasmodium falciparum IC50 77.0 nM 10.1016/j.ejmech.2017.11.033
Plasmodium falciparum Plasmodium falciparum IC50 78.0 nM 10.1016/j.ejmech.2013.10.028
Plasmodium falciparum Plasmodium falciparum IC50 78.0 nM 10.1021/np020244s
Plasmodium falciparum Plasmodium falciparum IC50 78.1 nM 10.1016/j.bmcl.2009.04.100
Plasmodium falciparum Plasmodium falciparum IC50 79.0 nM 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Plasmodium falciparum IC50 79.0 nM 10.1128/aac.01392-07
Plasmodium falciparum Plasmodium falciparum IC50 80.0 nM 10.1016/j.bmc.2011.05.046
Plasmodium falciparum Plasmodium falciparum IC50 80.0 nM 10.1016/j.bmcl.2003.12.069
Plasmodium falciparum Plasmodium falciparum IC50 80.0 nM 10.1016/j.bmcl.2007.10.027
Plasmodium falciparum Plasmodium falciparum IC50 80.0 nM 10.1016/j.ejmech.2015.05.020
Plasmodium falciparum Plasmodium falciparum IC50 80.0 nM 10.1021/jm100265s
Plasmodium falciparum Plasmodium falciparum IC50 80.0 nM 10.1021/np5007907
Plasmodium falciparum Plasmodium falciparum IC50 80.0 nM 10.1021/np800472q
Plasmodium falciparum Plasmodium falciparum IC50 80.0 nM 10.1039/C3MD00097D
Plasmodium falciparum Plasmodium falciparum IC50 80.5 nM 10.1021/jm701435h
Plasmodium falciparum Plasmodium falciparum IC50 81.0 nM 10.1021/np050315y
Plasmodium falciparum Plasmodium falciparum IC50 82.0 nM 10.1016/j.ejmech.2014.05.037
Plasmodium falciparum Plasmodium falciparum IC50 82.0 nM 10.1021/acs.jnatprod.7b00992
Plasmodium falciparum Plasmodium falciparum IC50 82.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 82.3 nM 10.1016/j.bmcl.2017.07.039
Plasmodium falciparum Plasmodium falciparum IC50 83.0 nM 10.1016/j.ejmech.2017.11.069
Plasmodium falciparum Plasmodium falciparum IC50 83.7 nM 10.1021/jm701435h
Plasmodium falciparum Plasmodium falciparum IC50 84.0 nM 10.1021/np0702133
Plasmodium falciparum Plasmodium falciparum IC50 84.0 nM 10.1128/aac.01392-07
Plasmodium falciparum Plasmodium falciparum IC50 85.0 nM 10.1021/jm200227r
Plasmodium falciparum Plasmodium falciparum IC50 87.0 nM 10.1007/s00044-010-9323-4
Plasmodium falciparum Plasmodium falciparum IC50 87.2 nM 10.1128/aac.01304-08
Plasmodium falciparum Plasmodium falciparum IC50 87.9 nM 10.1016/j.ejmech.2021.113518
Plasmodium falciparum Plasmodium falciparum IC50 88.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 89.0 nM 10.1016/j.bmc.2006.12.034
Plasmodium falciparum Plasmodium falciparum IC50 89.0 nM 10.1021/jm101383f
Plasmodium falciparum Plasmodium falciparum IC50 89.0 nM 10.1021/jm3007596
Plasmodium falciparum Plasmodium falciparum IC50 89.0 nM 10.1128/aac.01677-08
Plasmodium falciparum Plasmodium falciparum IC50 89.6 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 90.0 nM 10.1016/j.ejmech.2016.12.041
Plasmodium falciparum Plasmodium falciparum IC50 90.0 nM 10.1021/np8003529
Plasmodium falciparum Plasmodium falciparum IC50 90.0 nM 10.1021/np900622m
Plasmodium falciparum Plasmodium falciparum IC50 90.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 90.0 nM 10.1128/aac.01304-08
Plasmodium falciparum Plasmodium falciparum IC50 90.3 nM 10.1021/acs.jmedchem.8b01310
Plasmodium falciparum Plasmodium falciparum IC50 91.3 nM 10.1021/jm701435h
Plasmodium falciparum Plasmodium falciparum IC50 92.3 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 93.0 nM 10.1021/ml2002136
Plasmodium falciparum Plasmodium falciparum IC50 93.0 nM 10.1128/aac.00544-08
Plasmodium falciparum Plasmodium falciparum IC50 95.0 nM 10.1021/acs.jmedchem.8b01799
Plasmodium falciparum Plasmodium falciparum IC50 95.0 nM 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum IC50 95.0 nM 10.1021/jm980146x
Plasmodium falciparum Plasmodium falciparum IC50 95.1 nM 10.1021/jm8012757
Plasmodium falciparum Plasmodium falciparum IC50 96.4 nM 10.1016/j.bmc.2011.11.053
Plasmodium falciparum Plasmodium falciparum IC50 96.5 nM 10.1021/np010032f
Plasmodium falciparum Plasmodium falciparum IC50 96.8 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 97.0 nM 10.1016/j.bmc.2010.10.009
Plasmodium falciparum Plasmodium falciparum IC50 97.0 nM 10.1021/jm200149e
Plasmodium falciparum Plasmodium falciparum IC50 97.4 nM 10.1021/np200399t
Plasmodium falciparum Plasmodium falciparum IC50 99.0 nM 10.1016/j.ejmech.2013.01.032
Plasmodium falciparum Plasmodium falciparum IC50 99.0 nM 10.1016/j.ejmech.2014.07.048
Plasmodium falciparum Plasmodium falciparum IC50 99.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 99.0 nM 10.1021/jm9803828
Plasmodium falciparum Plasmodium falciparum IC50 99.7 nM 10.1128/aac.01334-07
Plasmodium falciparum Plasmodium falciparum IC50 99.97 nM 10.1021/jm00398a026
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1016/j.bmcl.2013.09.015
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1016/j.ejmech.2012.10.052
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1016/j.ejmech.2018.10.035
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1021/jm00089a025
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1021/jm001096a
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1021/jm060126s
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1021/ml4001084
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1021/np049576i
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1021/np800110e
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1021/np8004437
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1021/np900067k
Plasmodium falciparum Plasmodium falciparum IC50 100.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 101.0 nM 10.1128/aac.01392-07
Plasmodium falciparum Plasmodium falciparum IC50 101.1 nM 10.1128/aac.01412-09
Plasmodium falciparum Plasmodium falciparum IC50 101.8 nM 10.1016/j.bmcl.2014.09.088
Plasmodium falciparum Plasmodium falciparum IC50 102.0 nM 10.1016/j.ejmech.2014.11.022
Plasmodium falciparum Plasmodium falciparum IC50 102.0 nM 10.1021/jm060399n
Plasmodium falciparum Plasmodium falciparum IC50 102.0 nM 10.1021/jm1006484
Plasmodium falciparum Plasmodium falciparum IC50 102.0 nM 10.1021/jm900972u
Plasmodium falciparum Plasmodium falciparum IC50 102.0 nM 10.1021/jm990946n
Plasmodium falciparum Plasmodium falciparum IC50 102.2 nM 10.1128/aac.00669-07
Plasmodium falciparum Plasmodium falciparum IC50 103.5 nM 10.1021/jm0612867
Plasmodium falciparum Plasmodium falciparum IC50 105.3 nM 10.1016/j.bmc.2008.09.038
Plasmodium falciparum Plasmodium falciparum IC50 106.0 nM 10.1021/jm061002i
Plasmodium falciparum Plasmodium falciparum IC50 106.0 nM 10.1021/jm1006484
Plasmodium falciparum Plasmodium falciparum IC50 106.4 nM 10.1128/aac.00669-07
Plasmodium falciparum Plasmodium falciparum IC50 108.5 nM 10.1074/jbc.m608615200
Plasmodium falciparum Plasmodium falciparum IC50 110.0 nM 10.1016/j.bmcl.2004.05.026
Plasmodium falciparum Plasmodium falciparum IC50 110.0 nM 10.1016/j.bmcl.2005.03.050
Plasmodium falciparum Plasmodium falciparum IC50 110.0 nM 10.1016/j.ejmech.2020.113084
Plasmodium falciparum Plasmodium falciparum IC50 110.0 nM 10.1021/jm001096a
Plasmodium falciparum Plasmodium falciparum IC50 110.0 nM 10.1021/jm0602763
Plasmodium falciparum Plasmodium falciparum IC50 110.0 nM 10.1021/jm301506h
Plasmodium falciparum Plasmodium falciparum IC50 110.0 nM 10.1021/np0401866
Plasmodium falciparum Plasmodium falciparum IC50 110.0 nM 10.1021/np970030o
Plasmodium falciparum Plasmodium falciparum IC50 111.0 nM 10.1016/j.bmcl.2009.07.095
Plasmodium falciparum Plasmodium falciparum IC50 111.0 nM 10.1016/j.ejmech.2013.04.066
Plasmodium falciparum Plasmodium falciparum IC50 111.2 nM 10.1021/acs.jmedchem.8b01799
Plasmodium falciparum Plasmodium falciparum IC50 112.5 nM 10.1016/j.ejmech.2016.07.027
Plasmodium falciparum Plasmodium falciparum IC50 112.6 nM 10.1021/np900853n
Plasmodium falciparum Plasmodium falciparum IC50 112.8 nM 10.1021/jm8012757
Plasmodium falciparum Plasmodium falciparum IC50 113.0 nM 10.1016/j.ejmech.2018.01.039
Plasmodium falciparum Plasmodium falciparum IC50 114.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 114.0 nM 10.1128/aac.01175-08
Plasmodium falciparum Plasmodium falciparum IC50 114.4 nM 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Plasmodium falciparum IC50 115.0 nM 10.1128/aac.00967-06
Plasmodium falciparum Plasmodium falciparum IC50 115.0 ug.mL-1 10.1016/j.bmc.2007.10.055
Plasmodium falciparum Plasmodium falciparum IC50 115.2 nM 10.1016/j.bmc.2011.11.053
Plasmodium falciparum Plasmodium falciparum IC50 116.0 nM 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum IC50 117.0 nM 10.1021/acs.jmedchem.0c00131
Plasmodium falciparum Plasmodium falciparum IC50 118.0 nM 10.1021/jm200227r
Plasmodium falciparum Plasmodium falciparum IC50 120.0 nM 10.1016/j.bmc.2007.05.042
Plasmodium falciparum Plasmodium falciparum IC50 120.0 nM 10.1016/j.bmc.2013.12.032
Plasmodium falciparum Plasmodium falciparum IC50 120.0 nM 10.1016/j.bmcl.2006.01.027
Plasmodium falciparum Plasmodium falciparum IC50 120.0 nM 10.1016/j.bmcl.2006.07.057
Plasmodium falciparum Plasmodium falciparum IC50 120.0 nM 10.1016/j.bmcl.2015.02.044
Plasmodium falciparum Plasmodium falciparum IC50 120.0 nM 10.1016/j.ejmech.2007.06.007
Plasmodium falciparum Plasmodium falciparum IC50 120.0 nM 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum IC50 120.0 nM 10.1021/jm400004u
Plasmodium falciparum Plasmodium falciparum IC50 120.0 nM 10.1021/jm4004279
Plasmodium falciparum Plasmodium falciparum IC50 120.0 nM 10.1128/aac.01175-08
Plasmodium falciparum Plasmodium falciparum IC50 122.0 nM 10.1016/j.bmc.2009.08.003
Plasmodium falciparum Plasmodium falciparum IC50 123.0 nM 10.1016/j.bmcl.2009.07.095
Plasmodium falciparum Plasmodium falciparum IC50 124.0 nM 10.1016/j.bmcl.2016.01.052
Plasmodium falciparum Plasmodium falciparum IC50 124.0 nM 10.1021/jm0708634
Plasmodium falciparum Plasmodium falciparum IC50 124.0 nM 10.1021/jm800918v
Plasmodium falciparum Plasmodium falciparum IC50 124.0 nM 10.1021/jm801547t
Plasmodium falciparum Plasmodium falciparum IC50 124.0 nM 10.1021/jm900805v
Plasmodium falciparum Plasmodium falciparum IC50 124.0 nM 10.1021/jm901178d
Plasmodium falciparum Plasmodium falciparum IC50 124.24 nM 10.1021/jm800737y
Plasmodium falciparum Plasmodium falciparum IC50 124.61 nM 10.1128/aac.01144-06
Plasmodium falciparum Plasmodium falciparum IC50 125.0 nM 10.1016/j.bmc.2013.10.050
Plasmodium falciparum Plasmodium falciparum IC50 125.0 nM 10.1016/j.ejmech.2009.07.021
Plasmodium falciparum Plasmodium falciparum IC50 125.0 nM 10.1016/j.ejmech.2014.06.022
Plasmodium falciparum Plasmodium falciparum IC50 125.0 nM 10.1021/jm2009698
Plasmodium falciparum Plasmodium falciparum IC50 125.0 nM 10.1021/jm400508e
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1016/j.bmcl.2003.07.008
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1016/j.bmcl.2004.06.056
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1016/j.bmcl.2005.09.058
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1016/j.bmcl.2014.11.039
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1016/j.ejmech.2007.03.008
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1016/j.ejmech.2007.11.003
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1016/j.ejmech.2018.10.035
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1016/s0960-894x(02)00475-4
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1016/s0960-894x(03)00550-x
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1021/acs.jmedchem.1c00441
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1021/jm010842o
Plasmodium falciparum Plasmodium falciparum IC50 126.0 nM 10.1021/jm020960r
Plasmodium falciparum Plasmodium falciparum IC50 126.9 nM 10.1128/aac.01656-08
Plasmodium falciparum Plasmodium falciparum IC50 127.0 nM 10.1016/j.bmc.2008.11.009
Plasmodium falciparum Plasmodium falciparum IC50 129.78 nM 10.1021/jm8006905
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1007/s00044-008-9089-0
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1016/j.bmc.2007.10.031
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1016/j.bmc.2019.01.016
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1016/j.bmcl.2005.03.021
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1016/j.bmcl.2019.03.008
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1016/j.bmcl.2019.03.009
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1021/acs.jnatprod.7b00587
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1021/jm0310840
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1021/jm3002795
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1021/jm5018303
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1021/ml400447v
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1021/np030008x
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1021/np9002564
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1021/np900341f
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1021/np900834g
Plasmodium falciparum Plasmodium falciparum IC50 130.0 nM 10.1128/aac.00527-07
Plasmodium falciparum Plasmodium falciparum IC50 131.0 nM 10.1016/j.ejmech.2015.02.047
Plasmodium falciparum Plasmodium falciparum IC50 131.0 nM 10.1021/acs.jmedchem.0c00131
Plasmodium falciparum Plasmodium falciparum IC50 132.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 133.5 nM 10.1021/jm8012757
Plasmodium falciparum Plasmodium falciparum IC50 134.0 nM 10.1016/j.ejmech.2018.01.039
Plasmodium falciparum Plasmodium falciparum IC50 135.0 nM 10.1016/j.bmc.2008.05.079
Plasmodium falciparum Plasmodium falciparum IC50 135.0 nM 10.1021/jm200543y
Plasmodium falciparum Plasmodium falciparum IC50 135.0 nM 10.1021/np980144f
Plasmodium falciparum Plasmodium falciparum IC50 136.0 nM 10.1021/acs.jnatprod.8b00956
Plasmodium falciparum Plasmodium falciparum IC50 138.0 nM 10.1016/j.bmcl.2010.08.043
Plasmodium falciparum Plasmodium falciparum IC50 138.0 nM 10.1021/jm101383f
Plasmodium falciparum Plasmodium falciparum IC50 138.0 nM 10.1021/jm701606b
Plasmodium falciparum Plasmodium falciparum IC50 138.0 nM 10.1128/aac.00439-08
Plasmodium falciparum Plasmodium falciparum IC50 138.6 nM 10.1021/jm990946n
Plasmodium falciparum Plasmodium falciparum IC50 138.82 nM 10.1021/jm100938u
Plasmodium falciparum Plasmodium falciparum IC50 138.82 nM 10.1021/jm500033r
Plasmodium falciparum Plasmodium falciparum IC50 139.0 nM 10.1021/acs.jmedchem.5b01374
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1016/j.bmc.2017.02.016
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1016/j.bmcl.2017.02.049
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1016/j.ejmech.2011.01.008
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1016/j.ejmech.2013.08.004
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1016/j.ejmech.2013.08.037
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1016/j.ejmech.2014.04.076
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1016/j.ejmech.2016.02.028
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1016/j.ejmech.2020.113034
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1021/acs.jmedchem.2c01516
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1021/acsmedchemlett.1c00328
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1021/acsmedchemlett.6b00416
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1021/acsmedchemlett.9b00457
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1021/jm500811p
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1021/jm800106u
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1021/np970217f
Plasmodium falciparum Plasmodium falciparum IC50 140.0 nM 10.1039/C1MD00127B
Plasmodium falciparum Plasmodium falciparum IC50 140.0 ug.mL-1 10.1016/j.bmc.2006.10.006
Plasmodium falciparum Plasmodium falciparum IC50 141.0 nM 10.1021/np100625a
Plasmodium falciparum Plasmodium falciparum IC50 141.9 nM 10.1016/j.bmc.2021.116159
Plasmodium falciparum Plasmodium falciparum IC50 142.7 nM 10.1021/ml300242v
Plasmodium falciparum Plasmodium falciparum IC50 143.0 nM 10.1016/j.bmcl.2006.11.013
Plasmodium falciparum Plasmodium falciparum IC50 143.8 nM 10.1128/aac.01656-08
Plasmodium falciparum Plasmodium falciparum IC50 144.0 nM 10.1016/j.bmc.2011.10.037
Plasmodium falciparum Plasmodium falciparum IC50 144.0 nM 10.1021/acs.jmedchem.1c00441
Plasmodium falciparum Plasmodium falciparum IC50 144.0 nM 10.1021/acsmedchemlett.9b00457
Plasmodium falciparum Plasmodium falciparum IC50 144.0 nM 10.1021/jm00036a014
Plasmodium falciparum Plasmodium falciparum IC50 144.0 nM 10.1021/jm2009698
Plasmodium falciparum Plasmodium falciparum IC50 144.9 nM 10.1016/j.bmc.2008.05.017
Plasmodium falciparum Plasmodium falciparum IC50 144.9 nM 10.1021/jm050966r
Plasmodium falciparum Plasmodium falciparum IC50 144.9 nM 10.1021/jm070684m
Plasmodium falciparum Plasmodium falciparum IC50 145.0 nM 10.1016/j.ejmech.2015.02.047
Plasmodium falciparum Plasmodium falciparum IC50 145.0 nM 10.1016/j.ejmech.2020.113084
Plasmodium falciparum Plasmodium falciparum IC50 145.0 nM 10.1021/np800212g
Plasmodium falciparum Plasmodium falciparum IC50 145.4 nM 10.1016/j.bmcl.2011.03.090
Plasmodium falciparum Plasmodium falciparum IC50 147.0 nM 10.1016/j.bmc.2009.02.022
Plasmodium falciparum Plasmodium falciparum IC50 147.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 147.72 nM 10.1016/j.bmc.2009.01.021
Plasmodium falciparum Plasmodium falciparum IC50 148.0 nM 10.1016/j.bmcl.2011.07.112
Plasmodium falciparum Plasmodium falciparum IC50 148.0 nM 10.1021/jm8003619
Plasmodium falciparum Plasmodium falciparum IC50 148.0 nM 10.1039/C2MD20136D
Plasmodium falciparum Plasmodium falciparum IC50 149.0 nM 10.1016/j.bmc.2011.05.046
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.bmc.2008.05.007
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.bmc.2009.04.002
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.bmc.2010.06.066
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.bmc.2010.07.046
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.bmc.2013.06.059
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.bmc.2016.06.024
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.bmc.2016.12.006
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.bmc.2017.02.043
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.bmc.2019.03.061
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.bmcl.2008.05.068
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.ejmech.2009.09.040
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.ejmech.2011.11.022
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.ejmech.2014.01.023
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.ejmech.2017.07.041
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1016/j.ejmech.2018.09.060
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1021/acs.jnatprod.0c01119
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1021/acs.jnatprod.9b00149
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1021/jm030038x
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1021/jm2009698
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1021/np970010m
Plasmodium falciparum Plasmodium falciparum IC50 150.0 nM 10.1021/np970030o
Plasmodium falciparum Plasmodium falciparum IC50 150.8 nM 10.1021/acsmedchemlett.1c00589
Plasmodium falciparum Plasmodium falciparum IC50 151.0 nM 10.1016/j.ejmech.2014.02.038
Plasmodium falciparum Plasmodium falciparum IC50 151.0 nM 10.1016/j.ejmech.2014.03.059
Plasmodium falciparum Plasmodium falciparum IC50 151.0 nM 10.1021/jm200227r
Plasmodium falciparum Plasmodium falciparum IC50 151.0 nM 10.1021/jm901300d
Plasmodium falciparum Plasmodium falciparum IC50 152.0 nM 10.1128/aac.00169-08
Plasmodium falciparum Plasmodium falciparum IC50 152.2 nM 10.1016/j.bmc.2011.11.053
Plasmodium falciparum Plasmodium falciparum IC50 152.2 nM 10.1016/j.ejmech.2019.111983
Plasmodium falciparum Plasmodium falciparum IC50 154.0 nM 10.1021/acsmedchemlett.9b00457
Plasmodium falciparum Plasmodium falciparum IC50 154.0 nM 10.1021/jm300802s
Plasmodium falciparum Plasmodium falciparum IC50 154.0 nM 10.1021/jm301506h
Plasmodium falciparum Plasmodium falciparum IC50 154.0 nM 10.1021/jm8012757
Plasmodium falciparum Plasmodium falciparum IC50 154.0 nM 10.1021/jm801352s
Plasmodium falciparum Plasmodium falciparum IC50 154.73 nM 10.1016/j.bmcl.2016.05.024
Plasmodium falciparum Plasmodium falciparum IC50 155.0 nM 10.1016/j.ejmech.2010.03.006
Plasmodium falciparum Plasmodium falciparum IC50 155.0 nM 10.1021/jm7009292
Plasmodium falciparum Plasmodium falciparum IC50 156.0 nM 10.1016/j.bmcl.2017.12.060
Plasmodium falciparum Plasmodium falciparum IC50 156.0 nM 10.1021/jm031132g
Plasmodium falciparum Plasmodium falciparum IC50 157.0 nM 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum IC50 157.9 nM 10.1016/j.bmcl.2010.09.130
Plasmodium falciparum Plasmodium falciparum IC50 157.9 nM 10.1016/j.bmcl.2011.01.103
Plasmodium falciparum Plasmodium falciparum IC50 158.0 nM 10.1016/j.bmcl.2006.11.013
Plasmodium falciparum Plasmodium falciparum IC50 158.0 nM 10.1128/aac.00638-09
Plasmodium falciparum Plasmodium falciparum IC50 159.8 nM 10.1128/aac.01656-08
Plasmodium falciparum Plasmodium falciparum IC50 160.0 nM 10.1016/j.ejmech.2008.05.002
Plasmodium falciparum Plasmodium falciparum IC50 160.0 nM 10.1021/acs.jmedchem.1c00441
Plasmodium falciparum Plasmodium falciparum IC50 160.0 nM 10.1021/acs.jnatprod.5b00770
Plasmodium falciparum Plasmodium falciparum IC50 160.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 160.3 nM 10.1128/aac.01656-08
Plasmodium falciparum Plasmodium falciparum IC50 162.0 nM 10.1016/j.bmc.2011.05.046
Plasmodium falciparum Plasmodium falciparum IC50 162.3 nM 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum IC50 162.8 nM 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum IC50 163.0 nM 10.1021/acs.jmedchem.0c00539
Plasmodium falciparum Plasmodium falciparum IC50 163.0 nM 10.1021/acs.jmedchem.1c00748
Plasmodium falciparum Plasmodium falciparum IC50 163.0 nM 10.1021/acs.jmedchem.8b01961
Plasmodium falciparum Plasmodium falciparum IC50 163.0 nM 10.1128/aac.00544-08
Plasmodium falciparum Plasmodium falciparum IC50 163.9 nM 10.1021/jm500715u
Plasmodium falciparum Plasmodium falciparum IC50 163.91 nM 10.1021/jm500535j
Plasmodium falciparum Plasmodium falciparum IC50 165.6 nM 10.1016/j.bmc.2011.11.053
Plasmodium falciparum Plasmodium falciparum IC50 166.6 nM 10.1016/j.bmc.2011.01.030
Plasmodium falciparum Plasmodium falciparum IC50 167.0 nM 10.1021/acs.jnatprod.7b00876
Plasmodium falciparum Plasmodium falciparum IC50 167.0 nM 10.1128/aac.00951-09
Plasmodium falciparum Plasmodium falciparum IC50 168.74 nM 10.1016/j.bmc.2012.06.014
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1016/j.bmc.2012.05.061
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1016/j.bmcl.2018.02.051
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1016/j.ejmech.2010.08.049
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1016/j.ejmech.2018.06.025
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1016/s0960-894x(00)00684-3
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1016/s0960-894x(01)00798-3
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1016/s0960-894x(02)00555-3
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1016/s0960-894x(02)00837-5
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1016/s0960-894x(02)01003-x
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1016/s0960-894x(03)00179-3
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1016/s0960-894x(03)00353-6
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1021/jm200227r
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1021/jm2009698
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.1021/jm800106u
Plasmodium falciparum Plasmodium falciparum IC50 170.0 nM 10.6019/CHEMBL3392926
Plasmodium falciparum Plasmodium falciparum IC50 170.6 nM 10.1021/jm8012757
Plasmodium falciparum Plasmodium falciparum IC50 171.0 nM 10.1021/acs.jmedchem.0c00539
Plasmodium falciparum Plasmodium falciparum IC50 171.0 nM 10.1021/acs.jmedchem.1c00748
Plasmodium falciparum Plasmodium falciparum IC50 171.0 nM 10.1021/acs.jmedchem.8b01961
Plasmodium falciparum Plasmodium falciparum IC50 172.0 nM 10.1021/jm201216y
Plasmodium falciparum Plasmodium falciparum IC50 172.0 nM 10.1021/np020008h
Plasmodium falciparum Plasmodium falciparum IC50 172.0 nM 10.1128/aac.00124-09
Plasmodium falciparum Plasmodium falciparum IC50 173.0 nM 10.1016/j.ejmech.2020.112215
Plasmodium falciparum Plasmodium falciparum IC50 174.0 nM 10.1016/j.bmc.2011.05.046
Plasmodium falciparum Plasmodium falciparum IC50 174.0 nM 10.1021/acs.jmedchem.8b01464
Plasmodium falciparum Plasmodium falciparum IC50 174.5 nM 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum IC50 174.5 nM 10.1039/d1md00038a
Plasmodium falciparum Plasmodium falciparum IC50 175.0 nM 10.1021/jm001096a
Plasmodium falciparum Plasmodium falciparum IC50 178.0 nM 10.1016/j.bmcl.2011.08.116
Plasmodium falciparum Plasmodium falciparum IC50 179.2 nM 10.1021/jm020960r
Plasmodium falciparum Plasmodium falciparum IC50 180.0 nM 10.1016/j.bmcl.2006.11.051
Plasmodium falciparum Plasmodium falciparum IC50 180.0 nM 10.1016/j.ejmech.2014.11.022
Plasmodium falciparum Plasmodium falciparum IC50 180.0 nM 10.1021/acs.jmedchem.0c01480
Plasmodium falciparum Plasmodium falciparum IC50 180.0 nM 10.1021/acs.jnatprod.0c00929
Plasmodium falciparum Plasmodium falciparum IC50 180.0 nM 10.1021/ml2002136
Plasmodium falciparum Plasmodium falciparum IC50 180.0 nM 10.1021/np8000909
Plasmodium falciparum Plasmodium falciparum IC50 180.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 180.0 nM 10.1128/aac.00967-06
Plasmodium falciparum Plasmodium falciparum IC50 182.0 nM 10.1021/acs.jmedchem.8b01961
Plasmodium falciparum Plasmodium falciparum IC50 182.0 nM 10.1021/jm9901374
Plasmodium falciparum Plasmodium falciparum IC50 183.0 nM 10.1016/j.ejmech.2007.03.008
Plasmodium falciparum Plasmodium falciparum IC50 183.0 nM 10.1016/j.ejmech.2007.11.003
Plasmodium falciparum Plasmodium falciparum IC50 183.0 nM 10.1021/jm010842o
Plasmodium falciparum Plasmodium falciparum IC50 183.2 nM 10.1021/jm8012618
Plasmodium falciparum Plasmodium falciparum IC50 183.82 nM 10.1021/jm030796n
Plasmodium falciparum Plasmodium falciparum IC50 184.0 nM 10.1016/j.bmc.2011.10.039
Plasmodium falciparum Plasmodium falciparum IC50 185.38 nM 10.1021/jm020891g
Plasmodium falciparum Plasmodium falciparum IC50 186.0 nM 10.1016/j.ejmech.2013.09.008
Plasmodium falciparum Plasmodium falciparum IC50 186.0 nM 10.1021/acs.jmedchem.8b01961
Plasmodium falciparum Plasmodium falciparum IC50 186.0 nM 10.1021/jm4011466
Plasmodium falciparum Plasmodium falciparum IC50 187.34 nM 10.1016/j.bmcl.2009.02.013
Plasmodium falciparum Plasmodium falciparum IC50 189.0 nM 10.1021/jm701606b
Plasmodium falciparum Plasmodium falciparum IC50 189.0 nM 10.1128/aac.00439-08
Plasmodium falciparum Plasmodium falciparum IC50 190.0 nM 10.1007/s00044-007-9025-8
Plasmodium falciparum Plasmodium falciparum IC50 190.0 nM 10.1016/j.bmc.2009.01.024
Plasmodium falciparum Plasmodium falciparum IC50 190.0 nM 10.1016/j.bmc.2010.06.008
Plasmodium falciparum Plasmodium falciparum IC50 190.0 nM 10.1016/j.bmcl.2012.10.092
Plasmodium falciparum Plasmodium falciparum IC50 190.0 nM 10.1016/j.ejmech.2008.02.005
Plasmodium falciparum Plasmodium falciparum IC50 190.0 nM 10.1016/j.ejmech.2009.02.024
Plasmodium falciparum Plasmodium falciparum IC50 190.0 nM 10.1016/j.ejmech.2013.11.022
Plasmodium falciparum Plasmodium falciparum IC50 190.0 nM 10.1016/s0960-894x(02)00173-7
Plasmodium falciparum Plasmodium falciparum IC50 190.0 nM 10.1021/jm0108707
Plasmodium falciparum Plasmodium falciparum IC50 190.0 nM 10.1021/jm030974c
Plasmodium falciparum Plasmodium falciparum IC50 190.0 nM 10.1128/aac.01344-06
Plasmodium falciparum Plasmodium falciparum IC50 190.55 nM 10.1016/j.ejmech.2013.11.022
Plasmodium falciparum Plasmodium falciparum IC50 192.45 nM 10.1016/j.bmc.2008.05.017
Plasmodium falciparum Plasmodium falciparum IC50 194.0 nM 10.1016/j.bmcl.2017.03.065
Plasmodium falciparum Plasmodium falciparum IC50 194.0 nM 10.1021/acs.jmedchem.5b01156
Plasmodium falciparum Plasmodium falciparum IC50 194.0 nM 10.1021/acs.jmedchem.5b01605
Plasmodium falciparum Plasmodium falciparum IC50 194.0 nM 10.1021/acs.jmedchem.6b01265
Plasmodium falciparum Plasmodium falciparum IC50 194.0 nM 10.1021/acs.jmedchem.8b00382
Plasmodium falciparum Plasmodium falciparum IC50 194.0 nM 10.1021/acs.jmedchem.8b01769
Plasmodium falciparum Plasmodium falciparum IC50 194.0 nM 10.1021/acs.jnatprod.8b00154
Plasmodium falciparum Plasmodium falciparum IC50 194.0 nM 10.1021/jm201108k
Plasmodium falciparum Plasmodium falciparum IC50 194.0 nM 10.1021/jm500098s
Plasmodium falciparum Plasmodium falciparum IC50 196.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 196.0 nM 10.1021/acs.jmedchem.8b01972
Plasmodium falciparum Plasmodium falciparum IC50 196.0 nM 10.1128/aac.00951-09
Plasmodium falciparum Plasmodium falciparum IC50 198.0 nM 10.1016/j.bmc.2014.04.066
Plasmodium falciparum Plasmodium falciparum IC50 198.0 nM 10.1016/j.ejmech.2014.05.037
Plasmodium falciparum Plasmodium falciparum IC50 198.8 nM 10.1016/j.ejmech.2021.113981
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.bmc.2010.05.054
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.bmc.2011.10.044
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.bmc.2011.12.053
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.bmc.2020.115832
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.bmcl.2003.12.069
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.bmcl.2004.11.043
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.bmcl.2006.11.051
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.bmcl.2014.06.012
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.ejmech.2007.11.012
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.ejmech.2018.03.048
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.ejmech.2019.111927
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1016/j.ejmech.2021.113687
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1021/acs.jnatprod.6b00131
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1021/jm030545e
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1021/jm301678j
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1021/np100348x
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1021/np1008619
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1128/aac.00425-07
Plasmodium falciparum Plasmodium falciparum IC50 200.0 nM 10.1128/aac.00967-06
Plasmodium falciparum Plasmodium falciparum IC50 201.0 nM 10.1016/j.ejmech.2006.11.006
Plasmodium falciparum Plasmodium falciparum IC50 201.0 nM 10.1016/j.ejmech.2013.06.033
Plasmodium falciparum Plasmodium falciparum IC50 201.0 nM 10.1128/aac.00555-07
Plasmodium falciparum Plasmodium falciparum IC50 201.8 nM 10.1016/j.ejmech.2012.03.007
Plasmodium falciparum Plasmodium falciparum IC50 204.1 nM 10.1128/aac.01656-08
Plasmodium falciparum Plasmodium falciparum IC50 205.0 nM 10.1016/j.ejmech.2019.06.069
Plasmodium falciparum Plasmodium falciparum IC50 205.0 nM 10.1128/aac.01689-08
Plasmodium falciparum Plasmodium falciparum IC50 206.0 nM 10.1016/j.bmc.2015.02.061
Plasmodium falciparum Plasmodium falciparum IC50 206.0 nM 10.1021/jm501809x
Plasmodium falciparum Plasmodium falciparum IC50 207.0 nM 10.1016/j.ejmech.2018.08.063
Plasmodium falciparum Plasmodium falciparum IC50 208.0 nM 10.1021/acs.jmedchem.0c00539
Plasmodium falciparum Plasmodium falciparum IC50 208.0 nM 10.1021/acs.jmedchem.1c00748
Plasmodium falciparum Plasmodium falciparum IC50 208.0 nM 10.1021/acs.jmedchem.8b01961
Plasmodium falciparum Plasmodium falciparum IC50 209.5 nM 10.1016/j.bmc.2014.03.030
Plasmodium falciparum Plasmodium falciparum IC50 209.5 nM 10.1021/jm300887b
Plasmodium falciparum Plasmodium falciparum IC50 209.5 nM 10.1039/C4MD00091A
Plasmodium falciparum Plasmodium falciparum IC50 210.0 nM 10.1016/j.ejmech.2013.03.072
Plasmodium falciparum Plasmodium falciparum IC50 210.0 nM 10.1016/j.ejmech.2018.10.035
Plasmodium falciparum Plasmodium falciparum IC50 212.0 nM 10.1021/acsmedchemlett.9b00457
Plasmodium falciparum Plasmodium falciparum IC50 213.0 nM 10.1021/ml300362a
Plasmodium falciparum Plasmodium falciparum IC50 215.0 nM 10.1016/j.ejmech.2010.11.037
Plasmodium falciparum Plasmodium falciparum IC50 216.0 nM 10.1021/jm990946n
Plasmodium falciparum Plasmodium falciparum IC50 219.0 nM 10.1016/j.bmc.2014.12.018
Plasmodium falciparum Plasmodium falciparum IC50 219.0 nM 10.1016/j.bmcl.2009.07.095
Plasmodium falciparum Plasmodium falciparum IC50 219.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 219.0 nM 10.1021/jm990946n
Plasmodium falciparum Plasmodium falciparum IC50 220.0 nM 10.1016/j.bmcl.2009.04.060
Plasmodium falciparum Plasmodium falciparum IC50 220.0 nM 10.1021/ml400311r
Plasmodium falciparum Plasmodium falciparum IC50 220.0 nM 10.1021/np100415m
Plasmodium falciparum Plasmodium falciparum IC50 220.3 nM 10.1016/j.ejmech.2022.114408
Plasmodium falciparum Plasmodium falciparum IC50 220.36 nM 10.1128/aac.01479-06
Plasmodium falciparum Plasmodium falciparum IC50 221.9 nM 10.1016/j.ejmech.2013.05.046
Plasmodium falciparum Plasmodium falciparum IC50 222.0 nM 10.1021/acs.jmedchem.6b00719
Plasmodium falciparum Plasmodium falciparum IC50 222.0 nM 10.1021/acsmedchemlett.8b00496
Plasmodium falciparum Plasmodium falciparum IC50 224.0 nM 10.1021/np200499d
Plasmodium falciparum Plasmodium falciparum IC50 224.7 nM 10.1021/acs.jmedchem.7b00140
Plasmodium falciparum Plasmodium falciparum IC50 225.7 nM 10.1016/j.bmc.2008.09.038
Plasmodium falciparum Plasmodium falciparum IC50 228.0 nM 10.1039/C4MD00454J
Plasmodium falciparum Plasmodium falciparum IC50 229.0 nM 10.1016/j.bmc.2015.02.007
Plasmodium falciparum Plasmodium falciparum IC50 230.0 nM 10.1016/j.bmcl.2008.11.047
Plasmodium falciparum Plasmodium falciparum IC50 230.0 nM 10.1016/j.bmcl.2014.11.039
Plasmodium falciparum Plasmodium falciparum IC50 230.0 nM 10.1021/acs.jmedchem.0c01744
Plasmodium falciparum Plasmodium falciparum IC50 230.0 nM 10.1021/acs.jnatprod.5b00114
Plasmodium falciparum Plasmodium falciparum IC50 230.0 nM 10.1021/jm400637m
Plasmodium falciparum Plasmodium falciparum IC50 230.0 nM 10.1021/jm700938n
Plasmodium falciparum Plasmodium falciparum IC50 232.6 nM 10.1021/jm030181q
Plasmodium falciparum Plasmodium falciparum IC50 232.65 nM 10.1021/acsmedchemlett.9b00521
Plasmodium falciparum Plasmodium falciparum IC50 233.0 nM 10.1021/acsmedchemlett.9b00457
Plasmodium falciparum Plasmodium falciparum IC50 233.18 nM 10.1016/j.bmcl.2016.05.024
Plasmodium falciparum Plasmodium falciparum IC50 236.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 240.0 nM 10.1016/j.bmc.2006.09.055
Plasmodium falciparum Plasmodium falciparum IC50 240.0 nM 10.1016/j.bmc.2009.08.057
Plasmodium falciparum Plasmodium falciparum IC50 240.0 nM 10.1016/j.bmc.2012.05.061
Plasmodium falciparum Plasmodium falciparum IC50 240.0 nM 10.1016/j.bmcl.2004.05.063
Plasmodium falciparum Plasmodium falciparum IC50 240.0 nM 10.1016/j.bmcl.2006.08.009
Plasmodium falciparum Plasmodium falciparum IC50 240.0 nM 10.1016/j.bmcl.2015.12.032
Plasmodium falciparum Plasmodium falciparum IC50 240.0 nM 10.1021/jm00026a010
Plasmodium falciparum Plasmodium falciparum IC50 240.0 nM 10.1021/jm0310840
Plasmodium falciparum Plasmodium falciparum IC50 240.0 nM 10.1021/jm900629w
Plasmodium falciparum Plasmodium falciparum IC50 240.0 nM 10.1128/aac.01220-10
Plasmodium falciparum Plasmodium falciparum IC50 241.3 nM 10.1016/j.bmc.2012.07.041
Plasmodium falciparum Plasmodium falciparum IC50 242.3 nM 10.1016/j.ejmech.2012.07.037
Plasmodium falciparum Plasmodium falciparum IC50 243.0 nM 10.1021/acs.jmedchem.1c00441
Plasmodium falciparum Plasmodium falciparum IC50 244.76 nM 10.1021/jm701417a
Plasmodium falciparum Plasmodium falciparum IC50 245.0 nM 10.1016/j.bmc.2015.06.044
Plasmodium falciparum Plasmodium falciparum IC50 249.0 nM 10.1016/j.bmcl.2008.01.015
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/0960-894X(96)00040-6
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/j.bmc.2009.11.010
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/j.bmc.2010.11.014
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/j.bmc.2013.09.047
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/j.bmc.2019.01.044
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/j.bmcl.2007.06.070
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/j.bmcl.2008.11.098
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/j.bmcl.2012.10.126
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/j.bmcl.2017.07.081
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/j.ejmech.2009.02.024
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/j.ejmech.2017.07.052
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1016/s0960-894x(02)00430-4
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1021/jm960370r
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1021/jm9604944
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 250.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 251.3 nM 10.1021/jm500715u
Plasmodium falciparum Plasmodium falciparum IC50 251.34 nM 10.1021/jm500535j
Plasmodium falciparum Plasmodium falciparum IC50 252.4 nM 10.1021/jm901796s
Plasmodium falciparum Plasmodium falciparum IC50 254.0 nM 10.1016/j.bmcl.2015.08.030
Plasmodium falciparum Plasmodium falciparum IC50 254.0 nM 10.1016/j.ejmech.2013.05.023
Plasmodium falciparum Plasmodium falciparum IC50 254.05 nM 10.1016/j.ejmech.2013.01.017
Plasmodium falciparum Plasmodium falciparum IC50 255.0 nM 10.1016/j.bmc.2014.05.024
Plasmodium falciparum Plasmodium falciparum IC50 255.0 nM 10.1016/j.ejmech.2018.10.035
Plasmodium falciparum Plasmodium falciparum IC50 255.0 nM 10.1021/jm0109816
Plasmodium falciparum Plasmodium falciparum IC50 256.0 nM 10.1016/j.bmc.2008.03.005
Plasmodium falciparum Plasmodium falciparum IC50 257.6 nM 10.1016/j.ejmech.2015.06.024
Plasmodium falciparum Plasmodium falciparum IC50 258.0 nM 10.1016/j.bmcl.2006.07.060
Plasmodium falciparum Plasmodium falciparum IC50 259.0 nM 10.1016/j.ejmech.2010.08.062
Plasmodium falciparum Plasmodium falciparum IC50 260.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 260.0 nM 10.1021/acs.jmedchem.8b01961
Plasmodium falciparum Plasmodium falciparum IC50 260.0 nM 10.1021/jm061429p
Plasmodium falciparum Plasmodium falciparum IC50 260.0 nM 10.1021/jm7012375
Plasmodium falciparum Plasmodium falciparum IC50 260.0 nM 10.1021/jm701247k
Plasmodium falciparum Plasmodium falciparum IC50 260.0 nM 10.1021/jm801352s
Plasmodium falciparum Plasmodium falciparum IC50 262.0 nM 10.1128/aac.01392-07
Plasmodium falciparum Plasmodium falciparum IC50 262.4 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 263.0 nM 10.1021/acs.jmedchem.1c00483
Plasmodium falciparum Plasmodium falciparum IC50 263.0 nM 10.1021/jm401007p
Plasmodium falciparum Plasmodium falciparum IC50 264.0 nM 10.1016/j.bmc.2007.06.047
Plasmodium falciparum Plasmodium falciparum IC50 266.0 nM 10.1021/np0105275
Plasmodium falciparum Plasmodium falciparum IC50 266.58 nM 10.1128/aac.01479-06
Plasmodium falciparum Plasmodium falciparum IC50 267.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 267.0 nM 10.1021/jm990946n
Plasmodium falciparum Plasmodium falciparum IC50 267.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 270.0 nM 10.1016/j.bmcl.2006.11.051
Plasmodium falciparum Plasmodium falciparum IC50 270.0 nM 10.1016/j.ejmech.2020.112969
Plasmodium falciparum Plasmodium falciparum IC50 270.0 nM 10.1021/jm0101747
Plasmodium falciparum Plasmodium falciparum IC50 270.0 nM 10.1021/np050313d
Plasmodium falciparum Plasmodium falciparum IC50 271.0 nM 10.1128/aac.01469-08
Plasmodium falciparum Plasmodium falciparum IC50 272.0 nM 10.1016/j.bmcl.2021.128442
Plasmodium falciparum Plasmodium falciparum IC50 273.5 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 274.0 nM 10.1016/j.ejmech.2014.12.020
Plasmodium falciparum Plasmodium falciparum IC50 275.0 nM 10.1016/j.ejmech.2018.02.021
Plasmodium falciparum Plasmodium falciparum IC50 276.5 nM 10.1128/aac.00536-09
Plasmodium falciparum Plasmodium falciparum IC50 278.0 nM 10.1021/jm7013088
Plasmodium falciparum Plasmodium falciparum IC50 279.0 nM 10.1021/acs.jmedchem.0c01480
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1016/j.bmcl.2006.07.060
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1016/j.bmcl.2012.11.072
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1016/j.ejmech.2021.113227
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1021/acs.jmedchem.0c01411
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1021/jm061429p
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1021/jm200686d
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1021/jm300802s
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1021/jm7012375
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1021/jm701247k
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1021/jm801352s
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1021/np100737q
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1021/np200509g
Plasmodium falciparum Plasmodium falciparum IC50 280.0 nM 10.1021/np970217f
Plasmodium falciparum Plasmodium falciparum IC50 282.0 nM 10.1016/j.bmcl.2017.03.005
Plasmodium falciparum Plasmodium falciparum IC50 283.5 nM 10.1128/aac.01304-08
Plasmodium falciparum Plasmodium falciparum IC50 284.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 284.0 nM 10.1021/np000285t
Plasmodium falciparum Plasmodium falciparum IC50 284.0 nM 10.1021/np020070e
Plasmodium falciparum Plasmodium falciparum IC50 284.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 285.0 nM 10.1016/j.bmc.2015.02.007
Plasmodium falciparum Plasmodium falciparum IC50 287.89 nM 10.1016/j.bmc.2014.09.009
Plasmodium falciparum Plasmodium falciparum IC50 290.0 nM 10.1016/j.bmc.2007.10.083
Plasmodium falciparum Plasmodium falciparum IC50 290.0 nM 10.1016/j.ejmech.2018.10.041
Plasmodium falciparum Plasmodium falciparum IC50 290.0 nM 10.1021/jm301893b
Plasmodium falciparum Plasmodium falciparum IC50 290.05 nM 10.1128/aac.01479-06
Plasmodium falciparum Plasmodium falciparum IC50 291.0 nM 10.1016/j.bmcl.2007.09.056
Plasmodium falciparum Plasmodium falciparum IC50 291.0 nM 10.1021/acs.jnatprod.6b00967
Plasmodium falciparum Plasmodium falciparum IC50 291.0 nM 10.1021/acs.jnatprod.7b01041
Plasmodium falciparum Plasmodium falciparum IC50 293.0 nM 10.1128/aac.00757-07
Plasmodium falciparum Plasmodium falciparum IC50 293.3 nM 10.1128/aac.01656-08
Plasmodium falciparum Plasmodium falciparum IC50 299.0 nM 10.1128/aac.01175-08
Plasmodium falciparum Plasmodium falciparum IC50 299.45 nM 10.1128/aac.01479-06
Plasmodium falciparum Plasmodium falciparum IC50 300.0 nM 10.1016/j.bmc.2022.116830
Plasmodium falciparum Plasmodium falciparum IC50 300.0 nM 10.1016/j.bmcl.2011.05.125
Plasmodium falciparum Plasmodium falciparum IC50 300.0 nM 10.1016/j.bmcl.2015.03.077
Plasmodium falciparum Plasmodium falciparum IC50 300.0 nM 10.1016/j.bmcl.2018.03.026
Plasmodium falciparum Plasmodium falciparum IC50 300.0 nM 10.1016/j.ejmech.2020.113084
Plasmodium falciparum Plasmodium falciparum IC50 300.0 nM 10.1021/acs.jnatprod.5b01054
Plasmodium falciparum Plasmodium falciparum IC50 300.0 nM 10.1021/acs.jnatprod.6b00633
Plasmodium falciparum Plasmodium falciparum IC50 300.0 nM 10.1021/jm00035a017
Plasmodium falciparum Plasmodium falciparum IC50 300.0 nM 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum IC50 300.0 nM 10.1128/aac.00288-07
Plasmodium falciparum Plasmodium falciparum IC50 300.0 nM 10.1128/aac.00967-06
Plasmodium falciparum Plasmodium falciparum IC50 310.0 nM 10.1016/j.bmcl.2007.09.044
Plasmodium falciparum Plasmodium falciparum IC50 310.0 nM 10.1016/j.ejmech.2018.03.024
Plasmodium falciparum Plasmodium falciparum IC50 310.0 nM 10.1021/np200940b
Plasmodium falciparum Plasmodium falciparum IC50 311.0 nM 10.1016/j.bmcl.2009.07.095
Plasmodium falciparum Plasmodium falciparum IC50 315.0 nM 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum IC50 316.0 nM 10.1016/j.bmc.2014.09.040
Plasmodium falciparum Plasmodium falciparum IC50 316.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 316.3 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 317.0 nM 10.1016/j.ejmech.2017.02.024
Plasmodium falciparum Plasmodium falciparum IC50 317.1 nM 10.1016/j.bmc.2012.07.040
Plasmodium falciparum Plasmodium falciparum IC50 320.0 nM 10.1016/j.bmc.2007.05.038
Plasmodium falciparum Plasmodium falciparum IC50 320.0 nM 10.1016/j.bmc.2015.05.055
Plasmodium falciparum Plasmodium falciparum IC50 320.0 nM 10.1021/np0101705
Plasmodium falciparum Plasmodium falciparum IC50 320.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 325.0 nM 10.1039/C1MD00102G
Plasmodium falciparum Plasmodium falciparum IC50 328.0 nM 10.1021/ml400039r
Plasmodium falciparum Plasmodium falciparum IC50 330.4 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 338.0 nM 10.1016/j.bmcl.2006.01.009
Plasmodium falciparum Plasmodium falciparum IC50 340.0 nM 10.1016/j.bmcl.2012.10.094
Plasmodium falciparum Plasmodium falciparum IC50 340.0 nM 10.1016/j.ejmech.2009.03.041
Plasmodium falciparum Plasmodium falciparum IC50 340.0 nM 10.1021/ml400164t
Plasmodium falciparum Plasmodium falciparum IC50 340.0 nM 10.1021/np100325q
Plasmodium falciparum Plasmodium falciparum IC50 344.0 nM 10.1016/j.bmc.2015.07.051
Plasmodium falciparum Plasmodium falciparum IC50 344.0 nM 10.1016/j.bmcl.2012.06.010
Plasmodium falciparum Plasmodium falciparum IC50 347.0 nM 10.1016/j.bmcl.2014.12.037
Plasmodium falciparum Plasmodium falciparum IC50 347.0 nM 10.1016/j.bmcl.2015.01.003
Plasmodium falciparum Plasmodium falciparum IC50 347.29 nM 10.1021/jm500535j
Plasmodium falciparum Plasmodium falciparum IC50 347.3 nM 10.1021/jm500715u
Plasmodium falciparum Plasmodium falciparum IC50 349.35 nM 10.1016/j.bmc.2008.05.017
Plasmodium falciparum Plasmodium falciparum IC50 349.4 nM 10.1021/jm050966r
Plasmodium falciparum Plasmodium falciparum IC50 350.0 nM 10.1016/j.bmcl.2006.01.027
Plasmodium falciparum Plasmodium falciparum IC50 350.0 nM 10.1016/j.ejmech.2017.11.053
Plasmodium falciparum Plasmodium falciparum IC50 350.0 nM 10.1021/jm9902180
Plasmodium falciparum Plasmodium falciparum IC50 352.3 nM 10.1016/j.bmc.2007.07.012
Plasmodium falciparum Plasmodium falciparum IC50 352.3 nM 10.1016/j.bmcl.2009.12.030
Plasmodium falciparum Plasmodium falciparum IC50 352.3 nM 10.1016/j.bmcl.2014.02.044
Plasmodium falciparum Plasmodium falciparum IC50 354.7 nM 10.1016/j.ejmech.2013.08.046
Plasmodium falciparum Plasmodium falciparum IC50 360.0 nM 10.1016/j.bmc.2014.11.028
Plasmodium falciparum Plasmodium falciparum IC50 360.0 nM 10.1016/j.bmcl.2012.12.029
Plasmodium falciparum Plasmodium falciparum IC50 360.0 nM 10.1021/acs.jnatprod.9b00755
Plasmodium falciparum Plasmodium falciparum IC50 364.2 nM 10.1016/j.ejmech.2022.114408
Plasmodium falciparum Plasmodium falciparum IC50 367.0 nM 10.1016/j.ejmech.2014.10.061
Plasmodium falciparum Plasmodium falciparum IC50 370.0 nM 10.1021/acs.jnatprod.5b00317
Plasmodium falciparum Plasmodium falciparum IC50 374.66 nM 10.1021/jm500535j
Plasmodium falciparum Plasmodium falciparum IC50 374.7 nM 10.1021/jm500715u
Plasmodium falciparum Plasmodium falciparum IC50 378.0 nM 10.1016/j.bmcl.2013.12.067
Plasmodium falciparum Plasmodium falciparum IC50 378.3 nM 10.1016/j.bmc.2009.10.019
Plasmodium falciparum Plasmodium falciparum IC50 382.0 nM 10.1021/jm100057h
Plasmodium falciparum Plasmodium falciparum IC50 384.0 nM 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum IC50 389.5 nM 10.1128/aac.01656-08
Plasmodium falciparum Plasmodium falciparum IC50 390.0 nM 10.1021/ml3000808
Plasmodium falciparum Plasmodium falciparum IC50 392.09 nM 10.1021/jm800737y
Plasmodium falciparum Plasmodium falciparum IC50 392.1 nM 10.1016/j.ejmech.2022.114408
Plasmodium falciparum Plasmodium falciparum IC50 393.0 nM 10.1039/C1MD00022E
Plasmodium falciparum Plasmodium falciparum IC50 394.0 nM 10.1021/jm0600951
Plasmodium falciparum Plasmodium falciparum IC50 396.2 nM 10.1016/j.bmcl.2007.10.003
Plasmodium falciparum Plasmodium falciparum IC50 397.0 nM 10.1016/j.bmcl.2010.11.099
Plasmodium falciparum Plasmodium falciparum IC50 400.0 nM 10.1007/s00044-010-9325-2
Plasmodium falciparum Plasmodium falciparum IC50 400.0 nM 10.1016/j.bmc.2022.116830
Plasmodium falciparum Plasmodium falciparum IC50 400.0 nM 10.1016/j.bmcl.2003.12.069
Plasmodium falciparum Plasmodium falciparum IC50 400.0 nM 10.1016/j.ejmech.2011.06.021
Plasmodium falciparum Plasmodium falciparum IC50 400.0 nM 10.1016/j.ejmech.2017.12.051
Plasmodium falciparum Plasmodium falciparum IC50 400.0 nM 10.1016/j.ejmech.2021.113865
Plasmodium falciparum Plasmodium falciparum IC50 400.0 nM 10.1021/acs.jmedchem.6b01685
Plasmodium falciparum Plasmodium falciparum IC50 400.0 nM 10.1021/acs.jnatprod.1c00232
Plasmodium falciparum Plasmodium falciparum IC50 400.0 nM 10.1021/acsmedchemlett.8b00592
Plasmodium falciparum Plasmodium falciparum IC50 400.0 nM 10.1021/np100737q
Plasmodium falciparum Plasmodium falciparum IC50 400.0 nM 10.1128/aac.01175-08
Plasmodium falciparum Plasmodium falciparum IC50 405.0 nM 10.1021/jm701606b
Plasmodium falciparum Plasmodium falciparum IC50 405.0 nM 10.1128/aac.00439-08
Plasmodium falciparum Plasmodium falciparum IC50 406.0 nM 10.1021/acsmedchemlett.1c00354
Plasmodium falciparum Plasmodium falciparum IC50 410.0 nM 10.1016/j.bmc.2009.02.022
Plasmodium falciparum Plasmodium falciparum IC50 410.0 nM 10.1016/j.bmc.2009.06.020
Plasmodium falciparum Plasmodium falciparum IC50 410.0 nM 10.1016/j.bmcl.2007.12.069
Plasmodium falciparum Plasmodium falciparum IC50 410.0 nM 10.1016/j.bmcl.2009.01.103
Plasmodium falciparum Plasmodium falciparum IC50 410.0 nM 10.1021/np100196b
Plasmodium falciparum Plasmodium falciparum IC50 412.0 nM 10.1016/j.bmcl.2012.07.069
Plasmodium falciparum Plasmodium falciparum IC50 412.0 nM 10.1039/C5MD00115C
Plasmodium falciparum Plasmodium falciparum IC50 417.0 nM 10.1016/j.bmc.2012.10.019
Plasmodium falciparum Plasmodium falciparum IC50 420.0 nM 10.1016/j.bmcl.2009.10.106
Plasmodium falciparum Plasmodium falciparum IC50 420.0 nM 10.1016/j.ejmech.2011.04.002
Plasmodium falciparum Plasmodium falciparum IC50 420.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 420.0 nM 10.1016/j.ejmech.2019.01.047
Plasmodium falciparum Plasmodium falciparum IC50 420.0 nM 10.1021/acs.jmedchem.1c00354
Plasmodium falciparum Plasmodium falciparum IC50 420.0 nM 10.1021/np0780093
Plasmodium falciparum Plasmodium falciparum IC50 421.5 nM 10.1016/j.ejmech.2018.11.021
Plasmodium falciparum Plasmodium falciparum IC50 421.59 nM 10.1021/jm8006905
Plasmodium falciparum Plasmodium falciparum IC50 422.0 nM 10.1016/j.ejmech.2017.11.069
Plasmodium falciparum Plasmodium falciparum IC50 430.0 nM 10.1016/j.bmcl.2011.04.090
Plasmodium falciparum Plasmodium falciparum IC50 430.0 nM 10.1016/j.bmcl.2012.11.004
Plasmodium falciparum Plasmodium falciparum IC50 430.0 nM 10.1016/j.ejmech.2017.03.007
Plasmodium falciparum Plasmodium falciparum IC50 430.6 nM 10.1021/acsmedchemlett.0c00196
Plasmodium falciparum Plasmodium falciparum IC50 431.0 nM 10.1016/j.ejmech.2012.01.039
Plasmodium falciparum Plasmodium falciparum IC50 431.0 nM 10.1021/jm201676t
Plasmodium falciparum Plasmodium falciparum IC50 431.0 nM 10.1039/C8MD00608C
Plasmodium falciparum Plasmodium falciparum IC50 437.62 nM 10.1016/j.bmc.2012.07.041
Plasmodium falciparum Plasmodium falciparum IC50 440.0 nM 10.1016/j.bmc.2007.02.022
Plasmodium falciparum Plasmodium falciparum IC50 440.0 nM 10.1016/j.bmc.2009.10.005
Plasmodium falciparum Plasmodium falciparum IC50 440.0 nM 10.1016/j.ejmech.2017.03.010
Plasmodium falciparum Plasmodium falciparum IC50 440.0 nM 10.1016/j.ejmech.2018.06.025
Plasmodium falciparum Plasmodium falciparum IC50 440.0 nM 10.1021/ml4001084
Plasmodium falciparum Plasmodium falciparum IC50 440.7 nM 10.1016/j.bmc.2010.08.001
Plasmodium falciparum Plasmodium falciparum IC50 442.6 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 443.57 nM 10.1021/jm300588j
Plasmodium falciparum Plasmodium falciparum IC50 450.0 nM 10.1016/j.bmc.2017.06.029
Plasmodium falciparum Plasmodium falciparum IC50 451.4 nM 10.1021/jm901796s
Plasmodium falciparum Plasmodium falciparum IC50 452.4 nM 10.1021/jm060259d
Plasmodium falciparum Plasmodium falciparum IC50 455.0 nM 10.1039/C1MD00022E
Plasmodium falciparum Plasmodium falciparum IC50 456.0 nM 10.1021/acs.jmedchem.5b01374
Plasmodium falciparum Plasmodium falciparum IC50 456.2 nM 10.1021/jm100938u
Plasmodium falciparum Plasmodium falciparum IC50 456.2 nM 10.1021/jm500033r
Plasmodium falciparum Plasmodium falciparum IC50 457.0 nM 10.1016/j.ejmech.2019.111755
Plasmodium falciparum Plasmodium falciparum IC50 460.0 nM 10.1016/j.bmc.2015.06.056
Plasmodium falciparum Plasmodium falciparum IC50 460.0 nM 10.1021/acs.jnatprod.6b00758
Plasmodium falciparum Plasmodium falciparum IC50 462.02 nM 10.1021/acsmedchemlett.1c00031
Plasmodium falciparum Plasmodium falciparum IC50 463.0 nM 10.1016/j.bmcl.2012.07.028
Plasmodium falciparum Plasmodium falciparum IC50 463.0 nM 10.1016/j.ejmech.2017.04.063
Plasmodium falciparum Plasmodium falciparum IC50 469.2 nM 10.1016/j.ejmech.2021.113981
Plasmodium falciparum Plasmodium falciparum IC50 472.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 475.0 nM 10.1039/C1MD00022E
Plasmodium falciparum Plasmodium falciparum IC50 477.5 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 480.0 nM 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum IC50 481.2 nM 10.1016/j.bmc.2008.05.068
Plasmodium falciparum Plasmodium falciparum IC50 484.0 nM 10.1016/j.bmc.2009.09.026
Plasmodium falciparum Plasmodium falciparum IC50 485.3 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 491.53 nM 10.1021/jm070684m
Plasmodium falciparum Plasmodium falciparum IC50 493.2 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1016/j.bmc.2007.02.022
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1016/j.bmc.2009.10.005
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1016/j.bmc.2011.06.025
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1016/j.bmcl.2011.06.113
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1016/j.ejmech.2012.04.029
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1016/j.ejmech.2012.07.034
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1016/j.ejmech.2014.07.113
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1016/j.ejmech.2015.03.011
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1016/j.ejmech.2018.06.042
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1016/j.ejmech.2018.11.008
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1021/jm201216y
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1021/np0580558
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1021/np900067k
Plasmodium falciparum Plasmodium falciparum IC50 500.0 nM 10.1039/d2md00392a
Plasmodium falciparum Plasmodium falciparum IC50 501.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 501.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 503.0 nM 10.1016/j.ejmech.2016.11.057
Plasmodium falciparum Plasmodium falciparum IC50 508.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 508.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 518.0 nM 10.1016/j.ejmech.2019.111983
Plasmodium falciparum Plasmodium falciparum IC50 518.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC50 518.0 nM 10.1021/acs.jmedchem.1c00790
Plasmodium falciparum Plasmodium falciparum IC50 519.0 nM 10.1039/C1MD00022E
Plasmodium falciparum Plasmodium falciparum IC50 519.3 nM 10.1021/jm7009292
Plasmodium falciparum Plasmodium falciparum IC50 520.0 nM 10.1016/j.bmc.2007.02.022
Plasmodium falciparum Plasmodium falciparum IC50 520.0 nM 10.1016/j.bmc.2009.10.005
Plasmodium falciparum Plasmodium falciparum IC50 520.0 nM 10.1021/acs.jnatprod.6b00758
Plasmodium falciparum Plasmodium falciparum IC50 520.0 nM 10.1021/jm201056j
Plasmodium falciparum Plasmodium falciparum IC50 523.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 523.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 525.0 nM 10.1021/jm501809x
Plasmodium falciparum Plasmodium falciparum IC50 525.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 527.0 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 530.0 nM 10.1039/C3MD20377H
Plasmodium falciparum Plasmodium falciparum IC50 538.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 540.0 nM 10.1016/j.bmcl.2007.10.003
Plasmodium falciparum Plasmodium falciparum IC50 540.0 nM 10.1016/j.ejmech.2010.04.011
Plasmodium falciparum Plasmodium falciparum IC50 540.0 nM 10.1016/j.ejmech.2017.07.061
Plasmodium falciparum Plasmodium falciparum IC50 540.0 nM 10.1016/s0960-894x(01)00383-3
Plasmodium falciparum Plasmodium falciparum IC50 540.0 nM 10.1021/acs.jnatprod.7b00249
Plasmodium falciparum Plasmodium falciparum IC50 540.0 nM 10.1021/np000285t
Plasmodium falciparum Plasmodium falciparum IC50 543.0 nM 10.1021/acs.jnatprod.2c01041
Plasmodium falciparum Plasmodium falciparum IC50 546.0 nM 10.1016/j.ejmech.2021.113193
Plasmodium falciparum Plasmodium falciparum IC50 546.0 nM 10.1016/j.ejmech.2021.113685
Plasmodium falciparum Plasmodium falciparum IC50 550.0 nM 10.1016/j.bmc.2016.07.049
Plasmodium falciparum Plasmodium falciparum IC50 556.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 560.0 nM 10.1016/j.bmcl.2004.05.063
Plasmodium falciparum Plasmodium falciparum IC50 560.0 nM 10.1128/aac.00967-06
Plasmodium falciparum Plasmodium falciparum IC50 561.0 nM 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum IC50 563.0 nM 10.1016/j.bmc.2010.09.005
Plasmodium falciparum Plasmodium falciparum IC50 570.0 nM 10.1016/j.bmcl.2004.03.070
Plasmodium falciparum Plasmodium falciparum IC50 570.0 nM 10.1016/j.ejmech.2016.08.055
Plasmodium falciparum Plasmodium falciparum IC50 570.0 nM 10.1021/acsmedchemlett.8b00222
Plasmodium falciparum Plasmodium falciparum IC50 580.0 nM 10.1021/acs.jnatprod.1c00870
Plasmodium falciparum Plasmodium falciparum IC50 590.0 nM 10.1016/j.bmcl.2016.03.027
Plasmodium falciparum Plasmodium falciparum IC50 595.0 nM 10.1016/j.bmc.2015.02.061
Plasmodium falciparum Plasmodium falciparum IC50 600.0 nM 10.1016/j.ejmech.2014.06.014
Plasmodium falciparum Plasmodium falciparum IC50 600.0 nM 10.1016/j.ejmech.2016.04.059
Plasmodium falciparum Plasmodium falciparum IC50 600.0 nM 10.1016/j.ejmech.2016.09.029
Plasmodium falciparum Plasmodium falciparum IC50 600.0 nM 10.1021/np8000909
Plasmodium falciparum Plasmodium falciparum IC50 616.94 nM 10.1021/jm701417a
Plasmodium falciparum Plasmodium falciparum IC50 620.0 nM 10.1021/np100737q
Plasmodium falciparum Plasmodium falciparum IC50 630.0 nM 10.1016/j.bmcl.2014.11.039
Plasmodium falciparum Plasmodium falciparum IC50 630.6 nM 10.1128/aac.01412-09
Plasmodium falciparum Plasmodium falciparum IC50 632.0 nM 10.1016/j.ejmech.2011.02.029
Plasmodium falciparum Plasmodium falciparum IC50 645.0 nM 10.1016/j.bmcl.2007.10.003
Plasmodium falciparum Plasmodium falciparum IC50 648.6 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 660.0 nM 10.1016/j.ejmech.2020.112327
Plasmodium falciparum Plasmodium falciparum IC50 665.0 nM 10.1128/aac.00183-10
Plasmodium falciparum Plasmodium falciparum IC50 681.0 nM 10.1021/jm300831b
Plasmodium falciparum Plasmodium falciparum IC50 682.0 nM 10.1016/j.ejmech.2007.11.024
Plasmodium falciparum Plasmodium falciparum IC50 690.0 nM 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum IC50 697.94 nM 10.1016/j.ejmech.2019.05.043
Plasmodium falciparum Plasmodium falciparum IC50 700.0 nM 10.1016/j.bmc.2009.05.022
Plasmodium falciparum Plasmodium falciparum IC50 700.0 nM 10.1016/j.bmc.2010.06.067
Plasmodium falciparum Plasmodium falciparum IC50 700.0 nM 10.1016/j.bmcl.2007.10.027
Plasmodium falciparum Plasmodium falciparum IC50 700.0 nM 10.1016/j.bmcl.2009.08.013
Plasmodium falciparum Plasmodium falciparum IC50 700.0 nM 10.1016/j.ejmech.2009.10.022
Plasmodium falciparum Plasmodium falciparum IC50 700.0 nM 10.1016/j.ejmech.2009.11.005
Plasmodium falciparum Plasmodium falciparum IC50 710.0 nM 10.1016/j.bmc.2012.06.038
Plasmodium falciparum Plasmodium falciparum IC50 710.0 nM 10.1021/ml300008j
Plasmodium falciparum Plasmodium falciparum IC50 720.0 nM 10.1016/j.ejmech.2015.05.020
Plasmodium falciparum Plasmodium falciparum IC50 720.0 nM 10.1039/C3MD00097D
Plasmodium falciparum Plasmodium falciparum IC50 750.0 nM 10.1016/j.bmcl.2013.08.108
Plasmodium falciparum Plasmodium falciparum IC50 780.0 nM 10.1016/j.ejmech.2012.12.010
Plasmodium falciparum Plasmodium falciparum IC50 800.0 nM 10.1016/j.bmcl.2008.08.043
Plasmodium falciparum Plasmodium falciparum IC50 810.0 nM 10.1021/jm060899g
Plasmodium falciparum Plasmodium falciparum IC50 830.0 nM 10.1039/C8MD00098K
Plasmodium falciparum Plasmodium falciparum IC50 850.0 nM 10.1021/jm901300d
Plasmodium falciparum Plasmodium falciparum IC50 860.0 nM 10.1016/j.bmc.2007.05.038
Plasmodium falciparum Plasmodium falciparum IC50 879.0 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC50 900.0 nM 10.1016/j.bmc.2009.01.026
Plasmodium falciparum Plasmodium falciparum IC50 900.0 nM 10.1021/jm011046l
Plasmodium falciparum Plasmodium falciparum IC50 930.0 nM 10.1016/j.bmc.2015.01.031
Plasmodium falciparum Plasmodium falciparum IC50 950.0 nM 10.1021/jm0108707
Plasmodium falciparum Plasmodium falciparum IC50 980.0 nM 10.1021/np100737q
Plasmodium falciparum Plasmodium falciparum IC50 1000.0 nM 10.1016/j.bmc.2010.01.068
Plasmodium falciparum Plasmodium falciparum IC50 1000.0 nM 10.1021/acs.jmedchem.5b00114
Plasmodium falciparum Plasmodium falciparum IC50 1000.0 nM 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum IC50 1030.0 nM 10.1016/j.bmc.2010.06.033
Plasmodium falciparum Plasmodium falciparum IC50 1110.0 nM 10.1016/j.ejmech.2016.05.069
Plasmodium falciparum Plasmodium falciparum IC50 1120.0 nM 10.1016/j.ejmech.2020.113084
Plasmodium falciparum Plasmodium falciparum IC50 1160.0 nM 10.1021/ml500211c
Plasmodium falciparum Plasmodium falciparum IC50 1280.0 nM 10.1021/acs.jnatprod.2c00684
Plasmodium falciparum Plasmodium falciparum IC50 1330.0 nM 10.1016/j.ejmech.2020.112215
Plasmodium falciparum Plasmodium falciparum IC50 1500.0 nM 10.1039/d2md00392a
Plasmodium falciparum Plasmodium falciparum IC50 1600.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 1760.0 nM 10.1021/jm0108707
Plasmodium falciparum Plasmodium falciparum IC50 1828.0 nM 10.1016/j.ejmech.2017.09.040
Plasmodium falciparum Plasmodium falciparum IC50 1900.0 nM 10.1039/d2md00392a
Plasmodium falciparum Plasmodium falciparum IC50 1950.0 ug.mL-1 10.1021/np050315y
Plasmodium falciparum Plasmodium falciparum IC50 2000.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 3000.0 nM 10.1016/s0960-894x(01)00308-0
Plasmodium falciparum Plasmodium falciparum IC50 5500.0 nM 10.1016/j.ejmech.2012.12.019
Plasmodium falciparum Plasmodium falciparum IC50 10000.0 nM 10.1016/j.ejmech.2020.112215
Plasmodium falciparum Plasmodium falciparum IC50 10000.0 nM 10.1038/nchembio.215
Plasmodium falciparum Plasmodium falciparum IC50 10700.0 nM 10.1128/aac.00967-06
Plasmodium falciparum Plasmodium falciparum IC50 11000.0 nM 10.1016/j.ejmech.2014.09.077
Plasmodium falciparum Plasmodium falciparum IC50 11300.0 nM 10.1016/j.ejmech.2020.112330
Plasmodium falciparum Plasmodium falciparum IC50 12500.0 nM 10.1016/j.bmcl.2014.10.015
Plasmodium falciparum Plasmodium falciparum IC50 15000.0 nM 10.1016/j.ejmech.2013.06.002
Plasmodium falciparum Plasmodium falciparum IC50 16300.0 nM 10.1021/acs.jnatprod.7b00570
Plasmodium falciparum Plasmodium falciparum IC50 19000.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 21000.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 29640.0 nM 10.1016/j.ejmech.2019.01.047
Plasmodium falciparum Plasmodium falciparum IC50 29700.0 nM 10.1016/j.bmc.2008.11.050
Plasmodium falciparum Plasmodium falciparum IC50 32000.0 nM 10.1021/ml400015f
Plasmodium falciparum Plasmodium falciparum IC50 37000.0 nM 10.1016/s0960-894x(01)00383-3
Plasmodium falciparum Plasmodium falciparum IC50 60000.0 nM 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum IC50 64000.0 nM 10.1016/j.bmc.2014.08.005
Plasmodium falciparum Plasmodium falciparum IC50 80000.0 nM 10.1021/jm9803828
Plasmodium falciparum Plasmodium falciparum IC50 120000.0 nM 10.1016/j.ejmech.2014.05.050
Plasmodium falciparum Plasmodium falciparum IC50 166500.0 nM 10.1016/j.ejmech.2020.112330
Plasmodium falciparum Plasmodium falciparum IC50 177000.0 nM 10.1016/j.bmcl.2016.05.039
Plasmodium falciparum Plasmodium falciparum IC50 254000.0 nM 10.1016/j.ejmech.2012.12.019
Plasmodium falciparum Plasmodium falciparum IC50 277500.0 nM 10.1016/j.ejmech.2019.01.047
Plasmodium falciparum Plasmodium falciparum IC50 462000.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 480000.0 nM 10.1021/jm901357n
Plasmodium falciparum Plasmodium falciparum IC50 744100.0 nM 10.1016/j.bmc.2008.11.050
Plasmodium falciparum Plasmodium falciparum IC50 nan None 10.1016/j.bmcl.2011.05.131
Plasmodium falciparum Plasmodium falciparum IC50 nan None 10.1016/j.ejmech.2018.03.024
Plasmodium falciparum Plasmodium falciparum IC50 nan None 10.1016/s0960-894x(02)00802-8
Plasmodium falciparum Plasmodium falciparum IC50 nan None 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum IC50 nan None 10.1021/acsmedchemlett.0c00196
Plasmodium falciparum Plasmodium falciparum IC50 nan None 10.1021/jm011046l
Plasmodium falciparum Plasmodium falciparum IC50 nan None 10.1128/aac.00951-09
Plasmodium falciparum Plasmodium falciparum IC50 nan None 10.1128/aac.01412-09
Plasmodium falciparum Plasmodium falciparum IC80 40.1 ng/ml 10.1007/s00044-011-9694-1
Plasmodium falciparum Plasmodium falciparum IC90 0.00361 ug.mL-1 10.1016/S0960-894X(00)80047-5
Plasmodium falciparum Plasmodium falciparum IC90 0.0051 ug.mL-1 10.1021/jm200647u
Plasmodium falciparum Plasmodium falciparum IC90 0.00533 ug.mL-1 10.1021/jm0504252
Plasmodium falciparum Plasmodium falciparum IC90 0.015 ug well-1 10.1016/s0960-894x(02)00802-8
Plasmodium falciparum Plasmodium falciparum IC90 0.018 ug.mL-1 10.1016/j.bmcl.2005.09.008
Plasmodium falciparum Plasmodium falciparum IC90 0.02 ug.mL-1 10.1016/j.bmcl.2005.09.008
Plasmodium falciparum Plasmodium falciparum IC90 0.05524 ug.mL-1 10.1021/jm0504252
Plasmodium falciparum Plasmodium falciparum IC90 0.089 ug.mL-1 10.1021/jm200647u
Plasmodium falciparum Plasmodium falciparum IC90 0.09312 ug.mL-1 10.1016/S0960-894X(00)80047-5
Plasmodium falciparum Plasmodium falciparum IC90 0.1296 ug.mL-1 10.1128/aac.01023-06
Plasmodium falciparum Plasmodium falciparum IC90 0.139 ug.mL-1 10.1021/jm200647u
Plasmodium falciparum Plasmodium falciparum IC90 0.1987 ug.mL-1 10.1021/jm0504252
Plasmodium falciparum Plasmodium falciparum IC90 0.266 ug.mL-1 10.1021/jm200647u
Plasmodium falciparum Plasmodium falciparum IC90 13.72 nM 10.1021/jm070684m
Plasmodium falciparum Plasmodium falciparum IC90 15.94 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC90 15.94 nM 10.1021/jm8006905
Plasmodium falciparum Plasmodium falciparum IC90 16.11 nM 10.1021/jm100938u
Plasmodium falciparum Plasmodium falciparum IC90 16.11 nM 10.1021/jm500033r
Plasmodium falciparum Plasmodium falciparum IC90 16.38 nM 10.1021/jm800737y
Plasmodium falciparum Plasmodium falciparum IC90 17.58 nM 10.1021/jm701417a
Plasmodium falciparum Plasmodium falciparum IC90 17.6 nM 10.1021/jm050966r
Plasmodium falciparum Plasmodium falciparum IC90 17.63 nM 10.1016/j.bmc.2008.05.017
Plasmodium falciparum Plasmodium falciparum IC90 18.58 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC90 40.4 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 41.7 nM 10.1016/j.bmcl.2007.10.003
Plasmodium falciparum Plasmodium falciparum IC90 44.4 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 44.6 nM 10.1128/aac.00536-09
Plasmodium falciparum Plasmodium falciparum IC90 45.7 nM 10.1021/jm060259d
Plasmodium falciparum Plasmodium falciparum IC90 50.0 nM 10.1007/s00044-008-9089-0
Plasmodium falciparum Plasmodium falciparum IC90 50.0 nM 10.1016/j.bmcl.2005.01.011
Plasmodium falciparum Plasmodium falciparum IC90 59.2 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 63.0 nM 10.1021/np000285t
Plasmodium falciparum Plasmodium falciparum IC90 67.0 nM 10.1021/jm9002632
Plasmodium falciparum Plasmodium falciparum IC90 71.0 nM 10.1021/np020070e
Plasmodium falciparum Plasmodium falciparum IC90 84.0 nM 10.1021/np020070e
Plasmodium falciparum Plasmodium falciparum IC90 119.0 nM 10.1021/np000285t
Plasmodium falciparum Plasmodium falciparum IC90 152.81 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC90 166.7 nM 10.1021/jm060259d
Plasmodium falciparum Plasmodium falciparum IC90 243.15 nM 10.1021/jm800737y
Plasmodium falciparum Plasmodium falciparum IC90 250.0 nM 10.1007/s00044-008-9089-0
Plasmodium falciparum Plasmodium falciparum IC90 263.56 nM 10.1021/jm8006905
Plasmodium falciparum Plasmodium falciparum IC90 268.76 nM 10.1016/j.bmc.2008.05.017
Plasmodium falciparum Plasmodium falciparum IC90 268.76 nM 10.1021/jm070684m
Plasmodium falciparum Plasmodium falciparum IC90 268.8 nM 10.1021/jm050966r
Plasmodium falciparum Plasmodium falciparum IC90 301.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum IC90 302.68 nM 10.1128/aac.00312-09
Plasmodium falciparum Plasmodium falciparum IC90 316.2 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 345.08 nM 10.1021/jm701417a
Plasmodium falciparum Plasmodium falciparum IC90 349.35 nM 10.1021/jm070684m
Plasmodium falciparum Plasmodium falciparum IC90 373.25 nM 10.1021/jm100938u
Plasmodium falciparum Plasmodium falciparum IC90 373.25 nM 10.1021/jm500033r
Plasmodium falciparum Plasmodium falciparum IC90 397.09 nM 10.1016/j.bmc.2008.05.017
Plasmodium falciparum Plasmodium falciparum IC90 417.8 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 441.2 nM 10.1128/aac.00536-09
Plasmodium falciparum Plasmodium falciparum IC90 483.1 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 491.5 nM 10.1021/jm050966r
Plasmodium falciparum Plasmodium falciparum IC90 491.53 nM 10.1016/j.bmc.2008.05.017
Plasmodium falciparum Plasmodium falciparum IC90 500.0 nM 10.1016/j.bmcl.2005.01.011
Plasmodium falciparum Plasmodium falciparum IC90 529.86 nM 10.1021/jm800737y
Plasmodium falciparum Plasmodium falciparum IC90 613.8 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 639.71 nM 10.1021/jm8006905
Plasmodium falciparum Plasmodium falciparum IC90 685.5 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 693.4 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 697.97 nM 10.1021/jm100938u
Plasmodium falciparum Plasmodium falciparum IC90 697.97 nM 10.1021/jm500033r
Plasmodium falciparum Plasmodium falciparum IC90 700.0 nM 10.1128/aac.01344-06
Plasmodium falciparum Plasmodium falciparum IC90 721.8 nM 10.1016/j.bmcl.2007.10.003
Plasmodium falciparum Plasmodium falciparum IC90 802.2 nM 10.1021/jm060259d
Plasmodium falciparum Plasmodium falciparum IC90 912.0 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 991.8 nM 10.1016/j.bmcl.2007.10.003
Plasmodium falciparum Plasmodium falciparum IC90 1019.71 nM 10.1021/jm701417a
Plasmodium falciparum Plasmodium falciparum IC90 1129.8 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 1175.0 nM 10.1016/j.bmcl.2007.10.003
Plasmodium falciparum Plasmodium falciparum IC90 1241.7 nM 10.1021/jm9018383
Plasmodium falciparum Plasmodium falciparum IC90 1544.0 nM 10.1021/np000285t
Plasmodium falciparum Plasmodium falciparum IC90 1745.0 nM 10.1021/np000285t
Plasmodium falciparum Plasmodium falciparum IC90 1750.0 nM 10.1021/np020070e
Plasmodium falciparum Plasmodium falciparum IC90 nan None 10.1016/s0960-894x(02)00802-8
Plasmodium falciparum Plasmodium falciparum IC99 0.1723 ug.mL-1 10.1128/aac.01023-06
Plasmodium falciparum Plasmodium falciparum IC99 250.0 nM 10.1021/jm00036a014
Plasmodium falciparum Plasmodium falciparum IC99 436.3 nM 10.1128/aac.00312-09
Plasmodium falciparum Plasmodium falciparum IC99 531.0 nM 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum ID50 0.23 umol.kg-1 10.1021/jm0408013
Plasmodium falciparum Plasmodium falciparum Index 100.0 % 10.1016/s0960-894x(03)00509-2
Plasmodium falciparum Plasmodium falciparum Inhibition 17.2 % 10.1016/j.bmcl.2004.11.067
Plasmodium falciparum Plasmodium falciparum Inhibition 44.0 % 10.1021/jm500811p
Plasmodium falciparum Plasmodium falciparum Inhibition 54.0 % 10.1016/j.bmc.2008.11.062
Plasmodium falciparum Plasmodium falciparum Inhibition 86.0 % 10.1016/j.bmc.2008.11.062
Plasmodium falciparum Plasmodium falciparum Inhibition 88.4 % 10.1007/s00044-010-9397-z
Plasmodium falciparum Plasmodium falciparum Inhibition 97.0 % 10.1016/j.bmc.2008.11.062
Plasmodium falciparum Plasmodium falciparum Inhibition 97.1 % 10.1007/s00044-010-9397-z
Plasmodium falciparum Plasmodium falciparum Inhibition 99.8 % 10.1016/j.bmcl.2004.11.067
Plasmodium falciparum Plasmodium falciparum Inhibition 100.0 % 10.1007/s00044-010-9397-z
Plasmodium falciparum Plasmodium falciparum Inhibition 100.0 % 10.1016/j.bmc.2008.11.062
Plasmodium falciparum Plasmodium falciparum Inhibition 100.0 % 10.1016/j.bmcl.2009.02.120
Plasmodium falciparum Plasmodium falciparum Inhibition 100.0 % 10.1016/j.bmcl.2014.11.039
Plasmodium falciparum Plasmodium falciparum Inhibition 100.0 % 10.1021/acs.jnatprod.2c00484
Plasmodium falciparum Plasmodium falciparum Inhibition 100.0 % 10.1021/jm070773z
Plasmodium falciparum Plasmodium falciparum Inhibition 100.0 % 10.1021/jm4004279
Plasmodium falciparum Plasmodium falciparum Inhibition 100.0 % 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Inhibition nan % 10.1016/j.bmc.2011.06.002
Plasmodium falciparum Plasmodium falciparum Inhibition nan % 10.1016/j.ejmech.2010.08.049
Plasmodium falciparum Plasmodium falciparum Inhibition nan % 10.1021/jm1006484
Plasmodium falciparum Plasmodium falciparum Inhibition nan % 10.1021/jm500715u
Plasmodium falciparum Plasmodium falciparum Inhibition nan % 10.1128/aac.01478-07
Plasmodium falciparum Plasmodium falciparum Inhibition nan % 10.1128/aac.01512-09
Plasmodium falciparum Plasmodium falciparum LD50 0.1 uM 10.1021/np300750q
Plasmodium falciparum Plasmodium falciparum LD50 15.3 uM 10.1021/np300750q
Plasmodium falciparum Plasmodium falciparum log(activity) 0.7 None 10.1016/j.ejmech.2016.12.024
Plasmodium falciparum Plasmodium falciparum log(activity) 2.5 None 10.1016/j.ejmech.2016.12.024
Plasmodium falciparum Plasmodium falciparum log(ratio) 4.5 None 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum MIC 0.015 ug.mL-1 10.1016/j.bmc.2008.11.021
Plasmodium falciparum Plasmodium falciparum MIC 0.025 ug.mL-1 10.1016/j.bmc.2008.11.062
Plasmodium falciparum Plasmodium falciparum MIC 0.04 ug.mL-1 10.1007/s00044-007-9068-x
Plasmodium falciparum Plasmodium falciparum MIC 0.04 ug.mL-1 10.1016/s0960-894x(02)00320-7
Plasmodium falciparum Plasmodium falciparum MIC 0.04 ug.mL-1 10.1016/s0960-894x(02)00457-2
Plasmodium falciparum Plasmodium falciparum MIC 0.05 ug.mL-1 10.1016/j.bmc.2010.09.071
Plasmodium falciparum Plasmodium falciparum MIC 0.125 ug.mL-1 10.1007/s00044-013-0472-0
Plasmodium falciparum Plasmodium falciparum MIC 0.125 ug.mL-1 10.1016/j.bmc.2008.11.005
Plasmodium falciparum Plasmodium falciparum MIC 0.125 ug.mL-1 10.1016/j.bmc.2015.04.017
Plasmodium falciparum Plasmodium falciparum MIC 0.125 ug.mL-1 10.1016/j.bmcl.2010.09.107
Plasmodium falciparum Plasmodium falciparum MIC 0.125 ug.mL-1 10.1016/j.ejmech.2008.10.011
Plasmodium falciparum Plasmodium falciparum MIC 0.125 ug.mL-1 10.1016/j.ejmech.2016.08.039
Plasmodium falciparum Plasmodium falciparum MIC 390.0 nM 10.1021/jm061002i
Plasmodium falciparum Plasmodium falciparum MIC 391.0 nM 10.1016/j.bmcl.2008.04.030
Plasmodium falciparum Plasmodium falciparum MIC90 11.0 nM 10.1128/aac.00808-06
Plasmodium falciparum Plasmodium falciparum MIC>99 0.06 uM 10.1016/j.ejmech.2017.04.029
Plasmodium falciparum Plasmodium falciparum Parasitemia 0.1 % 10.1016/j.bmcl.2004.11.067
Plasmodium falciparum Plasmodium falciparum Parasitemia 32.2 % 10.1016/j.bmcl.2004.11.067
Plasmodium falciparum Plasmodium falciparum Ratio 13.0 None 10.1021/jm0310840
Plasmodium falciparum Plasmodium falciparum Ratio 23.17 None 10.1021/jm500033r
Plasmodium falciparum Plasmodium falciparum Ratio 24.0 None 10.1021/jm0310840
Plasmodium falciparum Plasmodium falciparum Ratio 43.32 None 10.1021/jm500033r
Plasmodium falciparum Plasmodium falciparum Ratio 57500.0 None 10.1007/s00044-008-9092-5
Plasmodium falciparum Plasmodium falciparum Ratio EC50 0.29 None 10.1021/jm1007903
Plasmodium falciparum Plasmodium falciparum Ratio EC50 33.0 None 10.1021/jm200636z
Plasmodium falciparum Plasmodium falciparum Ratio IC50 0.09 None 10.1016/j.ejmech.2021.113685
Plasmodium falciparum Plasmodium falciparum Ratio IC50 0.15 None 10.1016/j.bmc.2006.12.034
Plasmodium falciparum Plasmodium falciparum Ratio IC50 1.0 None 10.1016/j.bmcl.2011.05.125
Plasmodium falciparum Plasmodium falciparum Ratio IC50 1.5 None 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Ratio IC50 2.0 None 10.1016/j.ejmech.2020.113065
Plasmodium falciparum Plasmodium falciparum Ratio IC50 2.2 None 10.1016/j.bmc.2013.12.032
Plasmodium falciparum Plasmodium falciparum Ratio IC50 3.1 None 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum Ratio IC50 3.2 None 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum Ratio IC50 3.4 None 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum Ratio IC50 3.618 None 10.1016/j.bmc.2012.06.014
Plasmodium falciparum Plasmodium falciparum Ratio IC50 4.0 None 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Ratio IC50 4.2 None 10.1016/j.ejmech.2010.08.049
Plasmodium falciparum Plasmodium falciparum Ratio IC50 4.3 None 10.1021/jm901300d
Plasmodium falciparum Plasmodium falciparum Ratio IC50 4.7 None 10.1016/j.bmcl.2011.03.090
Plasmodium falciparum Plasmodium falciparum Ratio IC50 4.7 None 10.1016/j.bmcl.2014.06.012
Plasmodium falciparum Plasmodium falciparum Ratio IC50 5.0 None 10.1016/j.ejmech.2012.07.037
Plasmodium falciparum Plasmodium falciparum Ratio IC50 5.05 None 10.1016/j.ejmech.2010.07.068
Plasmodium falciparum Plasmodium falciparum Ratio IC50 5.3 None 10.1016/j.bmcl.2010.11.099
Plasmodium falciparum Plasmodium falciparum Ratio IC50 5.4 None 10.1021/jm2009698
Plasmodium falciparum Plasmodium falciparum Ratio IC50 6.3 None 10.1021/jm2009698
Plasmodium falciparum Plasmodium falciparum Ratio IC50 6.5 None 10.1021/jm2009698
Plasmodium falciparum Plasmodium falciparum Ratio IC50 6.9 None 10.1021/ml400311r
Plasmodium falciparum Plasmodium falciparum Ratio IC50 7.0 None 10.1016/j.bmcl.2010.09.130
Plasmodium falciparum Plasmodium falciparum Ratio IC50 7.0 None 10.1016/j.bmcl.2011.01.103
Plasmodium falciparum Plasmodium falciparum Ratio IC50 7.0 None 10.1016/j.bmcl.2012.06.010
Plasmodium falciparum Plasmodium falciparum Ratio IC50 7.0 None 10.1016/j.bmcl.2012.12.029
Plasmodium falciparum Plasmodium falciparum Ratio IC50 7.0 None 10.1016/j.ejmech.2013.08.004
Plasmodium falciparum Plasmodium falciparum Ratio IC50 7.02 None 10.1016/j.bmc.2015.07.051
Plasmodium falciparum Plasmodium falciparum Ratio IC50 7.27 None 10.1016/j.ejmech.2010.11.037
Plasmodium falciparum Plasmodium falciparum Ratio IC50 7.4 None 10.1021/jm2009698
Plasmodium falciparum Plasmodium falciparum Ratio IC50 7.78 None 10.1016/j.bmc.2015.01.036
Plasmodium falciparum Plasmodium falciparum Ratio IC50 8.0 None 10.1016/j.bmcl.2012.10.094
Plasmodium falciparum Plasmodium falciparum Ratio IC50 8.0 None 10.1021/jm200463z
Plasmodium falciparum Plasmodium falciparum Ratio IC50 9.1 None 10.1016/j.ejmech.2018.04.038
Plasmodium falciparum Plasmodium falciparum Ratio IC50 10.0 None 10.1016/j.bmc.2015.02.007
Plasmodium falciparum Plasmodium falciparum Ratio IC50 10.4 None 10.1016/j.bmc.2012.10.019
Plasmodium falciparum Plasmodium falciparum Ratio IC50 10.4 None 10.1021/jm800106u
Plasmodium falciparum Plasmodium falciparum Ratio IC50 10.5 None 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum Ratio IC50 10.6 None 10.1021/jm800106u
Plasmodium falciparum Plasmodium falciparum Ratio IC50 11.0 None 10.1016/j.ejmech.2021.113408
Plasmodium falciparum Plasmodium falciparum Ratio IC50 11.2 None 10.1128/aac.00536-09
Plasmodium falciparum Plasmodium falciparum Ratio IC50 11.31 None 10.1021/jm100938u
Plasmodium falciparum Plasmodium falciparum Ratio IC50 12.0 None 10.1016/j.bmcl.2012.10.126
Plasmodium falciparum Plasmodium falciparum Ratio IC50 12.0 None 10.1021/jm300802s
Plasmodium falciparum Plasmodium falciparum Ratio IC50 13.0 None 10.1016/j.ejmech.2014.12.020
Plasmodium falciparum Plasmodium falciparum Ratio IC50 13.6 None 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum Ratio IC50 13.92 None 10.1016/j.ejmech.2015.06.024
Plasmodium falciparum Plasmodium falciparum Ratio IC50 14.2 None 10.1021/jm300831b
Plasmodium falciparum Plasmodium falciparum Ratio IC50 14.7 None 10.1016/j.ejmech.2020.112330
Plasmodium falciparum Plasmodium falciparum Ratio IC50 15.0 None 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Ratio IC50 15.7 None 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum Ratio IC50 17.8 None 10.1016/j.bmc.2010.08.001
Plasmodium falciparum Plasmodium falciparum Ratio IC50 18.0 None 10.1016/j.bmc.2014.11.028
Plasmodium falciparum Plasmodium falciparum Ratio IC50 18.5 None 10.1016/j.bmcl.2006.08.009
Plasmodium falciparum Plasmodium falciparum Ratio IC50 18.7 None 10.1021/jm7009292
Plasmodium falciparum Plasmodium falciparum Ratio IC50 19.0 None 10.1016/j.bmcl.2015.12.032
Plasmodium falciparum Plasmodium falciparum Ratio IC50 19.6 None 10.1021/jm701478a
Plasmodium falciparum Plasmodium falciparum Ratio IC50 20.0 None 10.1016/j.bmc.2015.06.044
Plasmodium falciparum Plasmodium falciparum Ratio IC50 20.0 None 10.1021/jm400656s
Plasmodium falciparum Plasmodium falciparum Ratio IC50 20.3 None 10.1016/j.ejmech.2013.08.046
Plasmodium falciparum Plasmodium falciparum Ratio IC50 22.0 None 10.1021/jm300802s
Plasmodium falciparum Plasmodium falciparum Ratio IC50 22.3 None 10.1016/j.ejmech.2013.03.072
Plasmodium falciparum Plasmodium falciparum Ratio IC50 22.3 None 10.1021/jm300887b
Plasmodium falciparum Plasmodium falciparum Ratio IC50 22.3 None 10.1039/C4MD00091A
Plasmodium falciparum Plasmodium falciparum Ratio IC50 23.0 None 10.1016/j.bmcl.2014.09.088
Plasmodium falciparum Plasmodium falciparum Ratio IC50 23.73 None 10.1016/j.bmcl.2013.12.067
Plasmodium falciparum Plasmodium falciparum Ratio IC50 24.3 None 10.1021/jm901300d
Plasmodium falciparum Plasmodium falciparum Ratio IC50 25.0 None 10.1016/j.bmcl.2013.08.108
Plasmodium falciparum Plasmodium falciparum Ratio IC50 25.0 None 10.1021/jm101383f
Plasmodium falciparum Plasmodium falciparum Ratio IC50 25.2 None 10.1021/jm300588j
Plasmodium falciparum Plasmodium falciparum Ratio IC50 27.5 None 10.1016/j.bmc.2015.07.051
Plasmodium falciparum Plasmodium falciparum Ratio IC50 27.8 None 10.1021/acs.jmedchem.6b00719
Plasmodium falciparum Plasmodium falciparum Ratio IC50 29.0 None 10.1016/j.bmc.2015.05.055
Plasmodium falciparum Plasmodium falciparum Ratio IC50 29.5 None 10.1016/j.bmcl.2010.11.099
Plasmodium falciparum Plasmodium falciparum Ratio IC50 34.2 None 10.1021/acsmedchemlett.0c00196
Plasmodium falciparum Plasmodium falciparum Ratio IC50 35.0 None 10.1021/acs.jmedchem.2c01516
Plasmodium falciparum Plasmodium falciparum Ratio IC50 35.0 None 10.1021/jm501809x
Plasmodium falciparum Plasmodium falciparum Ratio IC50 38.18 None 10.1021/jm100938u
Plasmodium falciparum Plasmodium falciparum Ratio IC50 47.03 None 10.1016/j.ejmech.2013.05.023
Plasmodium falciparum Plasmodium falciparum Ratio IC50 47.22 None 10.1016/j.bmc.2014.05.024
Plasmodium falciparum Plasmodium falciparum Ratio IC50 60.6 None 10.1016/j.bmc.2014.09.009
Plasmodium falciparum Plasmodium falciparum Ratio IC50 71.0 None 10.1021/ml300008j
Plasmodium falciparum Plasmodium falciparum Ratio IC50 100.0 None 10.1016/j.ejmech.2011.08.043
Plasmodium falciparum Plasmodium falciparum Ratio IC50 140.39 None 10.1016/j.ejmech.2012.03.007
Plasmodium falciparum Plasmodium falciparum Resistance index 6.49 None 10.1016/j.bmcl.2004.05.063
Plasmodium falciparum Plasmodium falciparum Resistance index 15.5 None 10.1016/j.bmcl.2004.05.063
Plasmodium falciparum Plasmodium falciparum Reversal 0.0 % 10.1021/jm011046l
Plasmodium falciparum Plasmodium falciparum Survival 8.0 % 10.1021/acs.jmedchem.8b00143
Plasmodium falciparum Plasmodium falciparum Survival 9.0 day 10.1021/jm7013088
Plasmodium falciparum Plasmodium falciparum Survival 10.0 day 10.1021/jm400004u
Plasmodium falciparum Plasmodium falciparum Survival 16.0 % 10.1021/acs.jmedchem.8b00143
Plasmodium falciparum Plasmodium falciparum Survival 20.0 day 10.1021/jm7013088
Plasmodium falciparum Plasmodium falciparum Survival 100.0 % 10.1016/j.bmc.2009.08.057
Plasmodium falciparum Plasmodium falciparum T99.9% 34.0 hr 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum TIME 0.0 hr 10.1021/acs.jmedchem.7b00621
Plasmodium falciparum Plasmodium falciparum TIME 192.0 hr 10.1016/j.bmcl.2021.127884
Plasmodium falciparum Plasmodium falciparum TIME 336.0 hr 10.1128/aac.01636-09
Plasmodium falciparum Plasmodium falciparum TIME 480.0 hr 10.1016/j.bmc.2013.06.059
Plasmodium falciparum Protein kinase Pfmrk IC50 150000.0 nM 10.1021/jm040108f
Plasmodium falciparum (isolate 3D7) Plasmepsin V Activity nan None 10.1021/jm500797g
Plasmodium falciparum K1 Plasmodium falciparum K1 IC50 235.0 nM 10.6019/CHEMBL2113921
Plasmodium falciparum K1 Plasmodium falciparum K1 IC50 266.0 nM 10.6019/CHEMBL2113921
Plasmodium knowlesi Plasmodium knowlesi EC50 10.0 nM 10.1016/j.ejmech.2021.113253
Plasmodium knowlesi Plasmodium knowlesi IC50 10.0 nM 10.1021/ml2002136
Plasmodium malariae Plasmodium malariae IC50 14.0 nM 10.1128/aac.01122-10
Plasmodium malariae Plasmodium malariae IC50 127.9 nM 10.1128/aac.01122-10
Plasmodium malariae Plasmodium malariae Ratio 86.0 None 10.1128/aac.01122-10
Plasmodium vinckei Plasmodium vinckei ED100 100.0 mg/kg/day 10.1016/j.ejmech.2021.113408
Plasmodium vinckei petteri Plasmodium vinckei petteri ED100 16.0 mg/kg/day 10.1016/j.ejmech.2021.113408
Plasmodium vinckei petteri Plasmodium vinckei petteri ED50 1.1 mg.kg-1 10.1016/j.bmcl.2019.06.045
Plasmodium vinckei petteri Plasmodium vinckei petteri ED50 1.1 mg.kg-1 10.1021/jm3000328
Plasmodium vinckei petteri Plasmodium vinckei petteri ED50 3.4 mg.kg-1 10.1016/j.bmcl.2019.06.045
Plasmodium vinckei petteri Plasmodium vinckei petteri ED50 3.4 mg.kg-1 10.1021/jm3000328
Plasmodium vinckei petteri Plasmodium vinckei petteri ED50 5.0 mg/ml 10.1016/j.bmc.2010.06.008
Plasmodium vinckei petteri Plasmodium vinckei petteri ED50 5.5 mg/kg/day 10.1016/j.bmc.2012.05.061
Plasmodium vinckei petteri Plasmodium vinckei petteri Inhibition 0.0 % 10.1016/j.bmc.2010.06.008
Plasmodium vinckei petteri Plasmodium vinckei petteri Inhibition 0.0 % 10.1021/np8000909
Plasmodium vinckei petteri Plasmodium vinckei petteri Inhibition 0.0 % 10.1128/aac.00951-09
Plasmodium vinckei petteri Plasmodium vinckei petteri Inhibition 3.2 % 10.1016/j.bmc.2012.05.061
Plasmodium vinckei petteri Plasmodium vinckei petteri Inhibition 94.8 % 10.1016/j.bmc.2012.05.061
Plasmodium vinckei petteri Plasmodium vinckei petteri Inhibition 100.0 % 10.1016/j.bmc.2010.06.008
Plasmodium vinckei petteri Plasmodium vinckei petteri Inhibition 100.0 % 10.1021/np8000909
Plasmodium vinckei petteri Plasmodium vinckei petteri Inhibition 100.0 % 10.1128/aac.00951-09
Plasmodium vinckei petteri Plasmodium vinckei petteri MSD 9.5 day 10.1016/j.bmc.2012.05.061
Plasmodium vinckei petteri Plasmodium vinckei petteri MSD 13.0 day 10.1016/j.bmc.2012.05.061
Plasmodium vinckei petteri Plasmodium vinckei petteri MST 12.8 day 10.1128/aac.00951-09
Plasmodium vinckei petteri Plasmodium vinckei petteri MST 19.2 day 10.1128/aac.00951-09
Plasmodium vinckei petteri Plasmodium vinckei petteri MST 43.87 day 10.1128/aac.00951-09
Plasmodium vivax Plasmodium vivax CD90 2.5 mg kg-1 10.1021/jm00196a019
Plasmodium vivax Plasmodium vivax IC50 5.5 nM 10.1128/aac.01385-06
Plasmodium vivax Plasmodium vivax IC50 11.9 nM 10.1128/aac.01385-06
Plasmodium vivax Plasmodium vivax IC50 38.0 nM 10.1128/aac.00169-08
Plasmodium vivax Plasmodium vivax IC50 39.9 nM 10.1128/aac.01334-07
Plasmodium vivax Plasmodium vivax IC50 40.4 nM 10.1128/aac.01220-10
Plasmodium vivax Plasmodium vivax IC50 48.4 nM 10.1021/acs.jmedchem.8b01799
Plasmodium vivax Plasmodium vivax IC50 49.2 nM 10.1128/aac.00801-10
Plasmodium vivax Plasmodium vivax IC50 52.7 nM 10.1128/aac.01511-08
Plasmodium vivax Plasmodium vivax IC50 53.0 nM 10.1128/aac.01220-10
Plasmodium vivax Plasmodium vivax IC50 55.2 nM 10.1128/aac.01334-07
Plasmodium vivax Plasmodium vivax IC50 55.3 nM 10.1128/aac.00801-10
Plasmodium vivax Plasmodium vivax IC50 59.8 nM 10.1128/aac.01334-07
Plasmodium vivax Plasmodium vivax IC50 89.9 nM 10.1128/aac.01385-06
Plasmodium vivax Plasmodium vivax IC50 141.5 nM 10.1128/aac.00801-10
Plasmodium vivax Plasmodium vivax IC50 180.0 nM 10.1128/aac.01385-06
Plasmodium vivax Plasmodium vivax IC50 298.0 nM 10.1128/aac.01334-07
Plasmodium vivax Plasmodium vivax IC50 435.0 nM 10.1128/aac.01334-07
Plasmodium vivax Plasmodium vivax IC50 442.0 nM 10.1128/aac.00169-08
Plasmodium vivax Plasmodium vivax IC50 475.0 nM 10.1128/aac.01334-07
Plasmodium vivax Plasmodium vivax IC50 478.0 nM 10.1128/aac.01334-07
Plasmodium vivax Plasmodium vivax IC50 539.0 nM 10.1128/aac.01334-07
Plasmodium vivax Plasmodium vivax IC50 841.4 nM 10.1128/aac.01220-10
Plasmodium vivax Plasmodium vivax IC50 2427.0 nM 10.1128/aac.00801-10
Plasmodium vivax Plasmodium vivax IC50 2812.0 nM 10.1128/aac.01334-07
Plasmodium yoelii Plasmodium yoelii Activity 1.65 % 10.1021/np9605246
Plasmodium yoelii Plasmodium yoelii Activity 40.0 mg kg-1 10.1021/jm8012618
Plasmodium yoelii Plasmodium yoelii Activity 40.0 mg kg-1 10.1021/jm8012757
Plasmodium yoelii Plasmodium yoelii Activity 73.92 % 10.1016/j.bmcl.2009.03.026
Plasmodium yoelii Plasmodium yoelii Activity 94.26 % 10.1016/j.bmcl.2008.10.049
Plasmodium yoelii Plasmodium yoelii Activity 99.0 % 10.1021/jm300588j
Plasmodium yoelii Plasmodium yoelii Activity 99.05 % 10.1016/j.bmcl.2009.03.026
Plasmodium yoelii Plasmodium yoelii Activity 99.9 % 10.1016/j.bmcl.2008.10.049
Plasmodium yoelii Plasmodium yoelii Activity 99.9 % 10.1016/j.ejmech.2009.02.024
Plasmodium yoelii Plasmodium yoelii Activity 99.99 % 10.1016/j.ejmech.2013.05.023
Plasmodium yoelii Plasmodium yoelii Activity 99.99 % 10.1021/jm061002i
Plasmodium yoelii Plasmodium yoelii Activity 100.0 % 10.1021/acs.jmedchem.1c00748
Plasmodium yoelii Plasmodium yoelii Activity nan None 10.1016/j.bmc.2014.09.009
Plasmodium yoelii Plasmodium yoelii Activity nan None 10.1016/j.ejmech.2013.05.023
Plasmodium yoelii Plasmodium yoelii Activity nan None 10.1021/jm500147k
Plasmodium yoelii Plasmodium yoelii ED50 1.46 mg/kg.day 10.1021/acs.jmedchem.8b01961
Plasmodium yoelii Plasmodium yoelii ED50 1.5 mg/kg/day 10.1021/acs.jmedchem.0c00539
Plasmodium yoelii Plasmodium yoelii ED50 1.6 mg.kg-1 10.1021/jm020142z
Plasmodium yoelii Plasmodium yoelii ED50 1.8 mg.kg-1 10.1021/jm0705760
Plasmodium yoelii Plasmodium yoelii ED50 2.2 mg/kg/day 10.1021/jm500147k
Plasmodium yoelii Plasmodium yoelii ED50 3.3 mg.kg-1 10.1021/jm8012618
Plasmodium yoelii Plasmodium yoelii ED50 3.3 mg.kg-1 10.1021/jm8012757
Plasmodium yoelii Plasmodium yoelii ED90 1.5 mg/kg/day 10.1021/acs.jmedchem.1c00748
Plasmodium yoelii Plasmodium yoelii ED90 3.28 mg/kg.day 10.1021/acs.jmedchem.8b01961
Plasmodium yoelii Plasmodium yoelii ED90 3.3 mg/kg/day 10.1021/acs.jmedchem.0c00539
Plasmodium yoelii Plasmodium yoelii ED90 3.3 mg/kg/day 10.1021/acs.jmedchem.1c00748
Plasmodium yoelii Plasmodium yoelii ED90 4.4 mg kg-1 10.1021/jm8012618
Plasmodium yoelii Plasmodium yoelii ED90 4.4 mg kg-1 10.1021/jm8012757
Plasmodium yoelii Plasmodium yoelii ED90 28.0 mg kg-1 10.1021/jm020142z
Plasmodium yoelii Plasmodium yoelii IC50 0.00487 ug.mL-1 10.1016/j.bmc.2009.05.075
Plasmodium yoelii Plasmodium yoelii IC50 3.65 ug.mL-1 10.1016/j.bmc.2012.03.011
Plasmodium yoelii Plasmodium yoelii IC50 3.65 ug.mL-1 10.1039/C1MD00188D
Plasmodium yoelii Plasmodium yoelii IC50 3.75 ug.mL-1 10.1016/j.bmcl.2012.07.028
Plasmodium yoelii Plasmodium yoelii IC50 4.3 ug.mL-1 10.1016/j.ejmech.2013.01.017
Plasmodium yoelii Plasmodium yoelii IC50 106.0 nM 10.1016/j.ejmech.2009.02.024
Plasmodium yoelii Plasmodium yoelii IC50 1650.0 nM 10.1016/j.ejmech.2015.03.011
Plasmodium yoelii Plasmodium yoelii IC50 7700.0 nM 10.1016/j.ejmech.2012.12.019
Plasmodium yoelii Plasmodium yoelii Inhibition 93.6 % 10.1016/j.bmc.2012.03.011
Plasmodium yoelii Plasmodium yoelii Inhibition 93.9 % 10.1016/j.bmc.2012.03.011
Plasmodium yoelii Plasmodium yoelii Inhibition 99.0 % 10.1016/j.bmc.2012.03.011
Plasmodium yoelii Plasmodium yoelii Inhibition 99.0 % 10.1016/j.bmc.2014.09.009
Plasmodium yoelii Plasmodium yoelii Inhibition 99.05 % 10.1016/j.bmc.2009.05.075
Plasmodium yoelii Plasmodium yoelii Inhibition 99.9 % 10.1016/j.bmcl.2009.10.010
Plasmodium yoelii Plasmodium yoelii Inhibition 100.0 % 10.1016/j.bmcl.2005.10.044
Plasmodium yoelii Plasmodium yoelii MIC 390.0 nM 10.1016/j.ejmech.2009.02.024
Plasmodium yoelii Plasmodium yoelii MST 13.6 day 10.1016/j.bmc.2012.03.011
Plasmodium yoelii Plasmodium yoelii MST 16.5 day 10.1016/j.ejmech.2013.05.023
Plasmodium yoelii Plasmodium yoelii MST 28.0 day 10.1016/j.bmc.2012.03.011
Plasmodium yoelii Plasmodium yoelii MST 28.0 day 10.1021/jm300588j
Plasmodium yoelii Plasmodium yoelii NRD 64.0 mg/kg/day 10.1021/jm500147k
Plasmodium yoelii Plasmodium yoelii Survival 20.0 day 10.1016/j.ejmech.2009.02.024
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis Activity 100.0 % 10.1021/jm051130r
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis CD50 3.0 mg/kg/day 10.1128/aac.00967-06
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis CD50 7.0 mg/kg/day 10.1016/j.ejmech.2021.113408
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis CD50 nan None 10.1016/j.ejmech.2021.113408
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis CD50 nan None 10.1128/aac.00967-06
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis CD90 5.0 mg/kg/day 10.1128/aac.00967-06
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis CD90 23.0 mg/kg/day 10.1016/j.ejmech.2021.113408
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis CD90 nan None 10.1016/j.ejmech.2021.113408
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis CD90 nan None 10.1128/aac.00967-06
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis ED50 3.0 mg/kg/day 10.1128/aac.00967-06
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis ED50 5.0 mg/kg/day 10.1016/j.ejmech.2021.113408
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis ED50 nan None 10.1016/j.bmcl.2007.09.044
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis ED50 nan None 10.1016/j.ejmech.2021.113408
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis ED50 nan None 10.1128/aac.00967-06
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis ED90 5.0 mg/kg/day 10.1128/aac.00967-06
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis ED90 23.0 mg/kg/day 10.1016/j.ejmech.2021.113408
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis ED90 nan None 10.1016/j.ejmech.2021.113408
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis ED90 nan None 10.1128/aac.00967-06
Plasmodium yoelii nigeriensis Plasmodium yoelii nigeriensis IC50 2.5 mg kg-1 10.1016/j.ejmech.2018.10.035
Pseudomonas aeruginosa Pseudomonas aeruginosa DIZ nan None 10.1016/j.bmcl.2019.05.001
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 20000.0 nM 10.6019/CHEMBL4513161
Punta Toro virus Punta Toro virus EC50 100000.0 nM 10.1016/j.ejmech.2015.06.024
Rattus norvegicus Androgen Receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Cyclooxygenase-1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Hepatocyte TC50 50.0 uM 10.1021/jm100057h
Rattus norvegicus Hepatocyte TC50 77.0 uM 10.1021/jm100057h
Rattus norvegicus L6 CC50 92800.0 nM 10.1021/acs.jmedchem.8b01464
Rattus norvegicus L6 IC50 0.007 ug.mL-1 10.1016/j.ejmech.2013.08.008
Rattus norvegicus L6 IC50 188.5 nM 10.1016/j.ejmech.2006.11.006
Rattus norvegicus L6 IC50 7700.0 nM 10.1016/j.bmc.2006.12.034
Rattus norvegicus L6 IC50 43100.0 nM 10.1016/j.bmc.2009.08.057
Rattus norvegicus L6 IC50 70100.0 nM 10.1016/j.bmcl.2008.11.098
Rattus norvegicus L6 IC50 76500.0 nM 10.1016/j.bmc.2013.10.050
Rattus norvegicus L6 IC50 76500.0 nM 10.1016/j.ejmech.2014.06.022
Rattus norvegicus L6 IC50 76500.0 nM 10.1021/jm400508e
Rattus norvegicus L6 IC50 78000.0 nM 10.1021/jm500811p
Rattus norvegicus L6 IC50 90920.0 nM 10.1016/j.bmc.2017.02.043
Rattus norvegicus L6 IC50 91000.0 nM 10.1016/j.bmc.2017.02.016
Rattus norvegicus L6 IC50 91000.0 nM 10.1016/j.bmc.2019.115185
Rattus norvegicus L6 IC50 116900.0 nM 10.1016/j.ejmech.2009.03.014
Rattus norvegicus L6 IC50 116900.0 nM 10.1016/j.ejmech.2020.112969
Rattus norvegicus L6 IC50 117000.0 nM 10.1021/jm0708634
Rattus norvegicus L6 IC50 117000.0 nM 10.1021/jm800918v
Rattus norvegicus L6 IC50 117000.0 nM 10.1021/jm801547t
Rattus norvegicus L6 IC50 117000.0 nM 10.1021/jm900805v
Rattus norvegicus L6 IC50 117000.0 nM 10.1021/jm901178d
Rattus norvegicus L6 IC50 120000.0 nM 10.1016/j.bmcl.2016.04.053
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.bmc.2007.05.042
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.bmc.2008.05.007
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.bmc.2009.04.002
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.bmc.2010.07.046
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.bmc.2013.06.059
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.bmc.2016.06.024
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.bmc.2019.03.061
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.bmcl.2006.07.057
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.bmcl.2015.02.044
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.ejmech.2007.06.007
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.ejmech.2009.09.040
Rattus norvegicus L6 IC50 188500.0 nM 10.1016/j.ejmech.2011.11.022
Rattus norvegicus L6 IC50 117000000.0 nM 10.1016/j.ejmech.2013.06.033
Rattus norvegicus L6 IC50 nan nM 10.1021/jm0310840
Rattus norvegicus L6 IC50 nan None 10.1021/ml100120a
Rattus norvegicus L6 IC50 nan None 10.1021/ml400164t
Rattus norvegicus L6 IC50 nan None 10.1128/aac.00544-08
Rattus norvegicus Plasma Fu 0.43 None 10.1021/jm901371v
Rattus norvegicus Rattus norvegicus AUC 30.15 ng.hr.mL-1 10.1016/j.ejmech.2013.05.023
Rattus norvegicus Rattus norvegicus CL 0.15 L/hr 10.1016/j.ejmech.2013.05.023
Rattus norvegicus Rattus norvegicus Cmax 16346.76 nM 10.1016/j.ejmech.2013.05.023
Rattus norvegicus Rattus norvegicus IC50 90920.0 nM 10.1016/j.bmc.2016.12.006
Rattus norvegicus Rattus norvegicus MTD 240.0 mg kg-1 10.1016/j.bmc.2011.11.053
Rattus norvegicus Rattus norvegicus T1/2 9.5 hr 10.1016/j.ejmech.2013.05.023
Rattus norvegicus Rattus norvegicus Tmax 0.91 hr 10.1016/j.ejmech.2013.05.023
Rattus norvegicus Rattus norvegicus Vd 1.49 l 10.1016/j.ejmech.2013.05.023
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Potency 354.8 nM None
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity nan None 10.1021/acs.jmedchem.0c02056
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 520000.0 nM 10.1021/acs.jmedchem.0c02056
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 15000000.0 nM 10.1021/acs.jmedchem.0c02056
Saccharomyces cerevisiae Saccharomyces cerevisiae Ratio 30.0 None 10.1021/acs.jmedchem.0c02056
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 7.0 % 10.1021/jm300802s
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 14.0 % 10.1021/jm300802s
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 19.0 % 10.1021/jm300802s
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 21.0 % 10.1021/jm300802s
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 23.0 % 10.1021/jm300802s
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 24.0 % 10.1021/jm300802s
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 26.0 % 10.1021/jm300802s
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 29.0 % 10.1021/jm300802s
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 36.0 % 10.1021/jm300802s
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 38.0 % 10.1021/jm300802s
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 50.0 % 10.1021/jm300802s
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium Activity 61.0 % 10.1021/jm300802s
Semliki Forest virus Semliki Forest virus EC50 13800.0 nM 10.1021/np500271u
Semliki Forest virus Semliki Forest virus EC50 14000.0 nM 10.1021/acs.jnatprod.5b00116
Semliki Forest virus Semliki Forest virus EC50 14000.0 nM 10.1021/np300637t
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab IC50 7280.0 nM 10.1016/j.ejmech.2020.112559
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 1130.0 nM 10.1016/j.ejmech.2020.112559
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 1130.0 nM 10.1016/j.ejmech.2021.113157
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 1130.0 nM 10.1021/acs.jmedchem.0c00626
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 5470.0 nM 10.1016/j.ejmech.2021.113157
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 8200.0 nM 10.1016/j.bmcl.2023.129214
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 EC50 10900.0 nM 10.1021/acsmedchemlett.2c00123
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 ED50 4.4 uM 10.1016/j.ejmech.2021.113157
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.0509 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.6704 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 1130.0 nM 10.1021/acs.jmedchem.0c00502
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 5860.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 5888.44 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 7280.0 nM 10.1101/2020.03.20.999730
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 8000.0 nM 10.1016/j.bmcl.2020.127667
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 9460.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 9549.93 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 50200.0 nM 10.1021/acs.jnatprod.2c00580
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 10.0 % 10.1101/2020.04.13.039917
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 50.0 % 10.1101/2020.04.13.039917
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 85.0 % 10.1101/2020.04.13.039917
Severe acute respiratory syndrome coronavirus 2 Spike glycoprotein IC50 160.0 nM 10.1021/acs.jnatprod.0c01136
Severe acute respiratory syndrome coronavirus 2 Spike glycoprotein/Angiotensin-converting enzyme 2 IC50 7000.0 nM 10.1021/acs.jnatprod.1c00426
Severe acute respiratory syndrome-related coronavirus SARS-CoV EC50 1130.0 nM 10.1016/j.ejmech.2020.112687
Severe acute respiratory syndrome-related coronavirus SARS-CoV EC50 4100.0 nM 10.1016/j.ejmech.2020.112275
Severe acute respiratory syndrome-related coronavirus SARS-CoV EC50 4100.0 nM 10.1021/acs.jmedchem.0c00626
Severe acute respiratory syndrome-related coronavirus SARS-CoV IC50 8800.0 nM 10.1021/acs.jmedchem.0c00626
Sindbis virus Sindbis virus EC50 11000.0 nM 10.1021/acs.jnatprod.5b00116
Sindbis virus Sindbis virus EC50 11000.0 nM 10.1021/np300637t
Sindbis virus Sindbis virus EC50 11000.0 nM 10.1021/np500271u
Sindbis virus Sindbis virus EC50 100000.0 nM 10.1016/j.ejmech.2015.06.024
Staphylococcus aureus Staphylococcus aureus IC50 nan None 10.1016/j.bmc.2006.10.006
Staphylococcus aureus Staphylococcus aureus MIC 64.0 ug.mL-1 10.1021/jm201676t
Staphylococcus aureus Staphylococcus aureus MIC 20000.0 nM 10.6019/CHEMBL4513161
Streptococcus pneumoniae Streptococcus pneumoniae MIC 64.0 ug.mL-1 10.1021/jm201676t
Streptococcus pyogenes Streptococcus pyogenes MIC 64.0 ug.mL-1 10.1021/jm201676t
Sus scrofa LLC-PK1 IC50 nan None 10.1016/j.bmc.2006.10.006
Sus scrofa LLC-PK1 IC50 nan None 10.1016/j.ejmech.2015.05.020
Sus scrofa LLC-PK1 IC50 nan None 10.1039/C3MD00097D
Trichomonas vaginalis Trichomonas vaginalis IC50 30000.0 nM 10.1016/j.bmc.2010.07.008
Trichophyton benhamiae Trichophyton benhamiae MIC 50.0 ug.mL-1 10.1016/0960-894X(95)00577-G
Trypanosoma brucei Trypanosoma brucei GI50 15600.0 nM 10.1016/j.bmc.2012.11.009
Trypanosoma brucei Trypanosoma brucei IC50 nan nM 10.1016/j.bmcl.2004.05.026
Trypanosoma brucei brucei Trypanosoma brucei brucei EC50 nan None 10.1021/np2004825
Trypanosoma brucei brucei Trypanosoma brucei brucei IC50 nan None 10.1021/jm900946n
Trypanosoma brucei brucei Trypanosoma brucei brucei IC50 nan None 10.1021/np010419i
Trypanosoma brucei brucei Trypanosoma brucei brucei IC50 nan None 10.1021/np300638f
Trypanosoma brucei rhodesiense Rhodesain Ki nan None 10.1021/jm900946n
Trypanosoma brucei rhodesiense Trypanosoma brucei rhodesiense IC50 3810.0 nM 10.6019/CHEMBL3392926
Trypanosoma brucei rhodesiense Trypanosoma brucei rhodesiense IC50 nan None 10.1016/j.bmcl.2006.07.057
Trypanosoma brucei rhodesiense Trypanosoma brucei rhodesiense IC50 nan None 10.1016/j.ejmech.2014.06.022
Trypanosoma cruzi Trypanosoma cruzi GI50 22200.0 nM 10.1016/j.bmc.2012.11.009
Trypanosoma cruzi Trypanosoma cruzi IC50 30000.0 nM 10.1128/aac.00425-07
Trypanosoma cruzi Trypanosoma cruzi IC50 50000.0 nM 10.1016/j.bmc.2010.07.008
Trypanosoma cruzi Trypanosoma cruzi IC50 99250.0 nM 10.6019/CHEMBL3392926
Trypanosoma cruzi Trypanosoma cruzi IC50 nan nM 10.1016/j.bmcl.2004.05.026
Trypanosoma cruzi Trypanosoma cruzi IC50 nan None 10.1016/j.ejmech.2014.06.022
unidentified adenovirus unidentified adenovirus EC50 20000.0 nM 10.1016/j.ejmech.2015.06.024
Vaccinia virus Vaccinia virus EC50 20000.0 nM 10.1016/j.ejmech.2015.06.024
Vesicular stomatitis virus Vesicular stomatitis virus EC50 20000.0 nM 10.1016/j.ejmech.2015.06.024
Vesicular stomatitis virus Vesicular stomatitis virus EC50 100000.0 nM 10.1016/j.ejmech.2015.06.024
Zaire ebolavirus Zaire ebolavirus Activity nan None 10.1016/j.ejmech.2018.10.061
Zika virus Zika virus EC50 9820.0 nM 10.1021/acs.jmedchem.9b00775
Zika virus Zika virus EC50 12000.0 nM 10.1016/j.ejmech.2016.12.058
Zika virus Zika virus EC50 12000.0 nM 10.1016/j.ejmech.2017.01.007
Zika virus Zika virus Inhibition 47.0 % 10.1016/j.ejmech.2017.01.007
None ADMET Activity 0.72 % 10.1016/j.ejmech.2011.02.004
None ADMET Activity 84.0 % 10.1128/aac.00536-09
None ADMET Activity 99.0 % 10.1016/j.bmc.2019.01.016
None ADMET Activity 101.0 % 10.1016/j.bmc.2019.01.016
None ADMET Activity 12000.0 nM 10.1021/jm1006484
None ADMET Activity nan None 10.1007/s00044-012-0328-z
None ADMET Activity nan None 10.1016/j.bmcl.2011.05.131
None ADMET Activity nan None 10.1016/j.bmcl.2019.02.029
None ADMET Activity nan None 10.1016/j.ejmech.2018.10.061
None ADMET Activity nan None 10.1021/jm100057h
None ADMET Activity nan None 10.1021/jm201082a
None ADMET Activity nan None 10.1021/ml3000808
None ADMET Activity nan None 10.1021/np0601399
None ADMET Activity nan None 10.1021/np0701071
None ADMET Activity nan None 10.1124/dmd.112.050054
None ADMET Activity nan None 10.1128/aac.00288-07
None ADMET Activity nan None 10.1128/aac.00536-09
None ADMET B(DPB) 8.7 % 10.1021/jm040760a
None ADMET CC50 8500.0 nM 10.1128/aac.00843-07
None ADMET CC50 32000.0 nM 10.1016/j.bmc.2010.08.001
None ADMET CC50 32000.0 nM 10.1016/j.ejmech.2007.03.008
None ADMET CC50 38000.0 nM 10.1016/j.bmc.2010.08.001
None ADMET CC50 38000.0 nM 10.1016/j.bmc.2014.09.040
None ADMET CC50 88600.0 nM 10.1016/j.bmcl.2011.05.125
None ADMET CC50 235109.0 nM 10.1021/jm300588j
None ADMET CL 4.1 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET Cp 68.6 nM 10.1021/acsmedchemlett.9b00123
None ADMET Cp 80.7 nM 10.1021/acsmedchemlett.9b00123
None ADMET Cp 83.4 nM 10.1021/acsmedchemlett.9b00123
None ADMET Cytotoxicity nan None 10.1021/jm011046l
None ADMET delta logD -0.9 None 10.1021/jm0000564
None ADMET Drug uptake 0.5 10'-8mol 10.1021/jm1006484
None ADMET Drug uptake 0.7 10'-8mol 10.1021/jm1006484
None ADMET Drug uptake 10.0 % 10.1128/aac.00536-09
None ADMET Drug uptake 20.0 uM 10.1021/jm1006484
None ADMET Drug uptake 29.0 uM 10.1021/jm1006484
None ADMET Drug uptake 204.0 nM 10.1128/aac.01111-08
None ADMET Drug uptake 626.0 nM 10.1128/aac.01111-08
None ADMET Drug uptake 894.0 nM 10.1128/aac.01111-08
None ADMET Drug uptake nan None 10.1021/acs.jmedchem.7b00124
None ADMET ED50 7.8 ug ml-1 10.1021/np50091a005
None ADMET ED50 10.1 ug ml-1 10.1021/np50091a005
None ADMET ED50 20.0 ug ml-1 10.1021/np50091a005
None ADMET F 80.0 % 10.1021/jm0000564
None ADMET GI50 76130.0 nM 10.1016/j.bmc.2009.08.068
None ADMET GI50 76130.0 nM 10.1016/j.bmc.2010.01.001
None ADMET GI50 81260.0 nM 10.1016/j.bmc.2009.08.068
None ADMET GI50 81260.0 nM 10.1016/j.bmc.2010.01.001
None ADMET GI50 81260.0 nM 10.1016/j.ejmech.2010.05.046
None ADMET GI50 100000.0 nM 10.1016/j.bmcl.2013.10.025
None ADMET IC50 18.57 ug.mL-1 10.1016/j.bmcl.2013.02.075
None ADMET IC50 3460.0 nM 10.1021/jm901357n
None ADMET IC50 3630.0 nM 10.1016/j.ejmech.2014.11.016
None ADMET IC50 12000.0 nM 10.1021/jm900972u
None ADMET IC50 16000.0 nM 10.1021/jm200543y
None ADMET IC50 18400.0 nM 10.1016/j.bmc.2016.06.003
None ADMET IC50 20000.0 nM 10.1016/j.bmc.2015.05.055
None ADMET IC50 32000.0 nM 10.1016/j.bmc.2008.05.068
None ADMET IC50 38000.0 nM 10.1016/j.bmc.2008.05.068
None ADMET IC50 38000.0 nM 10.1016/j.bmc.2012.07.040
None ADMET IC50 38000.0 nM 10.1016/j.bmc.2012.07.041
None ADMET IC50 38000.0 nM 10.1016/j.bmc.2014.11.028
None ADMET IC50 50000.0 nM 10.1128/aac.00967-06
None ADMET IC50 63080.0 nM 10.1016/j.bmc.2015.11.007
None ADMET IC50 220000.0 nM 10.1124/dmd.112.050054
None ADMET IC50 nan ug.mL-1 10.1016/s0960-894x(02)00350-5
None ADMET IC50 nan None 10.1016/j.bmc.2013.12.032
None ADMET IC50 nan None 10.1016/j.bmc.2015.02.007
None ADMET IC50 nan None 10.1016/j.bmcl.2016.05.024
None ADMET IC50 nan None 10.1021/np800338p
None ADMET K 0.02012 /min 10.1021/acs.jmedchem.7b01417
None ADMET Ka 400000.0 M-1 10.1021/jm9902180
None ADMET LC50 200.0 ug.mL-1 10.1016/j.ejmech.2015.02.040
None ADMET LC50 100000.0 nM 10.1016/j.ejmech.2018.10.061
None ADMET LD50 383.0 ug ml-1 10.1016/j.ejmech.2011.09.025
None ADMET LD50 nan None 10.1016/j.bmcl.2015.03.077
None ADMET MLC50 385.3 uM 10.1016/j.bmc.2015.06.056
None ADMET MLD50 385.0 uM 10.1016/j.bmc.2016.07.049
None ADMET MLD50 1219.0 uM 10.1016/j.bmcl.2016.03.027
None ADMET Mortality 5.0 None 10.1021/jm970401y
None ADMET MRT 740.0 hr 10.1124/dmd.108.020479
None ADMET NA nan None 10.1021/jm010842o
None ADMET No. of survivals 0.0 None 10.1016/j.bmcl.2003.10.051
None ADMET No. of survivals 2.0 None 10.1016/j.bmcl.2003.10.051
None ADMET Papp 1.0 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 2.2 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 2.6 ucm/s 10.1124/dmd.110.034629
None ADMET Papp 3.4 ucm/s 10.1124/dmd.110.034629
None ADMET permeability 0.5 10'-6 cm/s 10.1021/jm100057h
None ADMET permeability 51.0 10'-6 cm/s 10.1021/jm100057h
None ADMET permeability 775.0 10'-6 cm/s 10.1021/jm100057h
None ADMET pKa 10.2 None 10.1021/jm030038x
None ADMET Ratio -20.0 None 10.1124/dmd.110.034629
None ADMET Ratio 0.8 None 10.1124/dmd.110.034629
None ADMET Ratio 2.2 None 10.1124/dmd.110.034629
None ADMET Ratio 3.76 None 10.1021/jm100057h
None ADMET Ratio 4.08 None 10.1021/jm100057h
None ADMET Ratio 36.64 None 10.1016/j.ejmech.2021.113685
None ADMET Ratio 65.0 None 10.1124/dmd.110.034629
None ADMET Ratio 241.0 None 10.1124/dmd.110.034629
None ADMET Ratio 6000.0 None 10.1021/jm1006484
None ADMET Ratio 9000.0 None 10.1021/jm1006484
None ADMET Ratio 21834.07 None 10.1021/jm8012757
None ADMET Ratio 22749.0 None 10.1016/j.ejmech.2014.04.076
None ADMET Ratio 22856.0 None 10.1128/aac.00536-09
None ADMET Ratio 22908.7 None 10.1016/j.bmc.2010.08.001
None ADMET Ratio CC50/EC50 3.0 None 10.1016/j.bmcl.2023.129214
None ADMET Ratio CC50/EC50 7.7 None 10.1021/acsmedchemlett.2c00123
None ADMET Ratio CC50/EC50 16.11 None 10.1016/j.bmc.2019.06.038
None ADMET Ratio CC50/EC50 25.1 None 10.1021/acsmedchemlett.2c00123
None ADMET Ratio CC50/EC50 37.5 None 10.1016/j.ejmech.2021.113722
None ADMET Ratio CC50/EC50 40.8 None 10.1021/acsmedchemlett.2c00123
None ADMET Ratio CC50/EC50 88.5 None 10.1016/j.ejmech.2020.112687
None ADMET Ratio CC50/EC50 88.5 None 10.1016/j.ejmech.2021.113157
None ADMET Ratio CC50/IC50 201.7 None 10.1016/j.ejmech.2020.113084
None ADMET Ratio CC50/IC50 1897.0 None 10.1016/j.bmcl.2021.128196
None ADMET Ratio CC50/IC50 nan None 10.1016/j.bmcl.2021.128196
None ADMET Ratio EC50 nan None 10.1021/jm1007903
None ADMET Ratio IC50 0.03 None 10.1016/j.ejmech.2021.113685
None ADMET Ratio IC50 7.2 None 10.1021/jm901357n
None ADMET Ratio IC50 18.4 None 10.1021/acs.jnatprod.2c01041
None ADMET Ratio IC50 36.63 None 10.1016/j.ejmech.2021.113193
None ADMET Ratio IC50 39.0 None 10.1016/j.ejmech.2021.113408
None ADMET Ratio IC50 103.0 None 10.1021/acs.jnatprod.1c00870
None ADMET Ratio IC50 122.0 None 10.1021/jm1006484
None ADMET Ratio IC50 132.0 None 10.1021/jm201676t
None ADMET Ratio IC50 182.0 None 10.1021/jm901357n
None ADMET Ratio IC50 194.0 None 10.1016/j.bmc.2012.05.061
None ADMET Ratio IC50 200.0 None 10.1021/jm201216y
None ADMET Ratio IC50 390.9 None 10.1016/j.bmc.2013.09.047
None ADMET Ratio IC50 456.0 None 10.1021/acs.jnatprod.2c01041
None ADMET Ratio IC50 1000.0 None 10.1021/acs.jmedchem.0c01744
None ADMET Ratio IC50 1090.0 None 10.1016/j.ejmech.2007.03.003
None ADMET Ratio IC50 1550.0 None 10.1021/acs.jnatprod.1c00870
None ADMET Ratio IC50 2505.0 None 10.1021/acs.jmedchem.1c00748
None ADMET Ratio IC50 8432.5 None 10.1016/j.ejmech.2021.113330
None ADMET Ratio IC50 10000.0 None 10.1016/j.bmcl.2016.05.039
None ADMET Ratio IC50 12267.0 None 10.1021/acs.jmedchem.0c01744
None ADMET Ratio LD50/ED50 35.0 None 10.1016/j.bmcl.2007.09.044
None ADMET Ratio LD50/IC50 11074.0 None 10.1021/acsmedchemlett.1c00589
None ADMET Selectivity 30.0 None 10.1038/s41586-020-2286-9
None ADMET Selectivity index 20.61 None 10.1101/2020.03.20.999730
None ADMET T1/2 0.5733 hr 10.1021/acs.jmedchem.7b01417
None ADMET T1/2 1.0 hr 10.1021/acs.jmedchem.0c00539
None ADMET T1/2 570.0 hr 10.1124/dmd.108.020479
None ADMET TC50 18.6 uM 10.1021/jm801352s
None ADMET TC50 nan None 10.1021/jm701247k
None ADMET TI 6.0 None 10.1016/j.bmc.2009.05.011
None ADMET TI 6.0 None 10.1016/j.bmc.2011.11.053
None ADMET TI 100.0 None 10.1016/j.bmcl.2009.12.030
None ADMET TI 13241.0 None 10.1021/acs.jmedchem.8b00143
None ADMET Vdss 140.0 L.kg-1 10.1124/dmd.108.020479
None CFU-GM Average colony count 5.0 None 10.1016/0960-894X(95)00326-O
None CFU-GM Average colony count 48.0 None 10.1016/0960-894X(95)00326-O
None CFU-GM Average colony count 54.0 None 10.1016/0960-894X(95)00326-O
None CFU-GM Average colony count 56.0 None 10.1016/0960-894X(95)00326-O
None Erythrocyte Activity 40.0 nmol/hr 10.1128/aac.00536-09
None Erythrocyte Activity nan None 10.1016/j.ejmech.2021.113271
None Erythrocyte CC50 100.0 ug.mL-1 10.1016/j.bmc.2016.09.013
None Erythrocyte CC50 466.66 ppm 10.1016/j.bmc.2019.06.038
None Erythrocyte HC10 20.0 uM 10.6019/CHEMBL4513161
None Erythrocyte HC50 1500.0 uM 10.1016/j.ejmech.2017.10.051
None Heme Activity 3.8 None 10.1021/jm8012618
None Heme Activity 4.0 None 10.1021/jm8012618
None Heme Activity 4.4 None 10.1021/jm8012618
None Heme Activity 4.69 None 10.1021/jm8012618
None Heme Activity 4.7 None 10.1021/jm8012618
None Heme Activity 5.0 None 10.1021/jm8012618
None Heme Activity 5.3 None 10.1021/jm8012618
None Heme Activity 6.23 None 10.1021/jm8012618
None Heme Activity nan None 10.1021/acsmedchemlett.0c00196
None Heme IC50 1.23 equiv 10.1016/j.bmc.2015.02.061
None Heme IC50 1.71 molar ratio 10.1016/j.bmc.2014.09.040
None Heme IC50 1.91 equiv 10.1128/aac.01466-08
None Heme IC50 20060.0 nM 10.1016/j.ejmech.2014.07.048
None Heme IC50 24000.0 nM 10.1007/s00044-007-9025-8
None Heme IC50 30000.0 nM 10.1039/C4MD00091A
None Heme IC50 170000.0 nM 10.1016/j.bmc.2014.09.009
None Heme IC50 374100.0 nM 10.1128/aac.01466-08
None Heme Inhibition 75.0 % 10.1016/j.ejmech.2012.05.022
None Heme Inhibition nan % 10.1128/aac.00544-08
None Heme Ka 4.0 10'-5/M 10.1016/j.ejmech.2014.11.022
None Heme Ka 5.5 10'4/M 10.1039/C3MD00019B
None Heme Kd 4000.0 nM 10.1021/jm1006484
None Heme log K 4.65 None 10.1016/j.ejmech.2013.05.046
None Heme log K 4.65 None 10.1016/j.ejmech.2014.10.061
None Heme log K 4.67 None 10.1016/j.ejmech.2018.02.021
None Heme log K 4.72 None 10.1016/j.ejmech.2018.01.082
None Heme log K 4.82 None 10.1016/j.ejmech.2016.07.055
None Heme log K 5.1 None 10.1016/j.bmc.2021.116159
None Heme log K 5.1 None 10.1021/acsmedchemlett.9b00521
None Heme log K 5.15 None 10.1016/j.ejmech.2013.05.046
None Heme log K 5.15 None 10.1016/j.ejmech.2014.10.061
None Heme log K 5.16 None 10.1016/j.ejmech.2018.02.021
None Heme log K 5.18 None 10.1016/j.bmc.2021.116159
None Heme log K 5.18 None 10.1021/acsmedchemlett.9b00521
None Heme log K 5.2 None 10.1016/j.ejmech.2016.07.055
None Heme log K 5.23 None 10.1016/j.ejmech.2018.01.082
None Heme logKa 4.65 None 10.1016/j.ejmech.2015.06.024
None Heme logKa 5.15 None 10.1016/j.ejmech.2015.06.024
None Heme log Ks 3.0 None 10.1021/jm8012757
None Heme log Ks 3.5 None 10.1021/jm8012757
None Heme log Ks 3.8 None 10.1021/jm8012757
None Heme log Ks 4.0 None 10.1021/jm8012757
None Heme log Ks 4.4 None 10.1021/jm8012757
None Heme log Ks 4.5 None 10.1021/jm8012757
None Heme log Ks 4.6 None 10.1021/jm8012757
None Heme log Ks 4.69 None 10.1021/jm8012757
None Heme log Ks 4.7 None 10.1021/jm8012757
None Heme log Ks 4.82 None 10.1016/j.ejmech.2012.03.007
None Heme log Ks 5.0 None 10.1021/jm8012757
None Heme log Ks 5.9 None 10.1021/jm8012757
None Heme log Ks 6.1 None 10.1021/jm8012757
None Heme log Ks 6.23 None 10.1021/jm8012757
None Heme log Ks 6.3 None 10.1021/jm8012757
None Heme log Ks 6.7 None 10.1021/jm8012757
None Hepatocyte IC50 1900.0 nM 10.1016/j.bmcl.2006.01.009
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity HepSE_bilirubinemia 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LTKB_BD DILI severity score 3.0 None 10.1016/j.drudis.2011.05.007
None Molecular identity unknown Activity nan None 10.1021/acs.jmedchem.5b00511
None Molecular identity unknown Activity nan None 10.1021/np970433o
None Molecular identity unknown CAR 1859.0 None 10.1021/jm960370r
None mu-oxodimeric heme log K 5.58 None 10.1016/j.ejmech.2013.05.046
None mu-oxodimeric heme log K 5.58 None 10.1016/j.ejmech.2014.10.061
None mu-oxodimeric heme log K 5.6 None 10.1016/j.ejmech.2016.07.055
None mu-oxodimeric heme log K 5.68 None 10.1016/j.ejmech.2018.01.082
None mu-oxodimeric heme log K nan None 10.1016/j.ejmech.2018.02.021
None mu-oxodimeric heme logKa 5.58 None 10.1016/j.ejmech.2015.06.024
None mu-oxodimeric heme log Ks 5.6 None 10.1016/j.ejmech.2012.03.007
None NON-PROTEIN TARGET Activity 45.0 % 10.1016/j.ejmech.2016.08.055
None NON-PROTEIN TARGET Activity 50.0 % 10.1021/acsmedchemlett.6b00466
None NON-PROTEIN TARGET Activity 50.0 % 10.1021/jm200265b
None NON-PROTEIN TARGET Activity 97.1 % 10.1016/j.ejmech.2016.07.055
None NON-PROTEIN TARGET CC50 30000.0 nM 10.1016/j.ejmech.2016.09.029
None NON-PROTEIN TARGET EC50 110.0 nM 10.1016/s0960-894x(99)00291-7
None NON-PROTEIN TARGET EC50 2300.0 nM 10.1016/j.bmcl.2011.04.090
None NON-PROTEIN TARGET EC50 10000.0 nM 10.1021/acs.jnatprod.5b00073
None NON-PROTEIN TARGET EC50 10000.0 nM 10.1021/np500271u
None NON-PROTEIN TARGET EC50 11000.0 nM 10.1021/acs.jnatprod.5b00116
None NON-PROTEIN TARGET EC50 11000.0 nM 10.1021/jm401844c
None NON-PROTEIN TARGET EC50 11000.0 nM 10.1021/np300637t
None NON-PROTEIN TARGET EC90 21.0 uM 10.1021/jm401844c
None NON-PROTEIN TARGET ED50 1.8 mg.kg-1 10.1021/jm200265b
None NON-PROTEIN TARGET Fu 0.43 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET GI50 9500.0 nM 10.1016/j.bmc.2009.08.054
None NON-PROTEIN TARGET GI50 10200.0 nM 10.1016/j.bmc.2009.08.054
None NON-PROTEIN TARGET GI50 23400.0 nM 10.1016/j.bmc.2009.08.054
None NON-PROTEIN TARGET GI50 44440.0 nM 10.1016/j.bmcl.2013.10.025
None NON-PROTEIN TARGET Hepatotoxicity (acute) 0.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 1.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 0.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 7.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET IC50 0.02 ug.mL-1 10.1016/j.bmc.2006.10.062
None NON-PROTEIN TARGET IC50 1.1 ug.mL-1 10.1021/jm400460d
None NON-PROTEIN TARGET IC50 2.154 ug.mL-1 10.1016/j.ejmech.2016.07.055
None NON-PROTEIN TARGET IC50 7.8 nM 10.1128/aac.01122-10
None NON-PROTEIN TARGET IC50 23.2 nM 10.1128/aac.01122-10
None NON-PROTEIN TARGET IC50 750.0 nM 10.1016/j.bmcl.2016.09.038
None NON-PROTEIN TARGET IC50 3600.0 nM 10.1021/ml500348p
None NON-PROTEIN TARGET IC50 10000.0 nM 10.1021/acs.jmedchem.5b00511
None NON-PROTEIN TARGET IC50 25000.0 nM 10.1021/ml500348p
None NON-PROTEIN TARGET IC50 50370.0 nM 10.1021/acs.jmedchem.5b00511
None NON-PROTEIN TARGET IC50 50610.0 nM 10.6019/CHEMBL3392926
None NON-PROTEIN TARGET IC50 52000.0 nM 10.1021/ml500348p
None NON-PROTEIN TARGET IC50 58850.0 nM 10.6019/CHEMBL3392926
None NON-PROTEIN TARGET IC50 76000.0 nM 10.1021/ml500348p
None NON-PROTEIN TARGET IC50 100000.0 nM 10.1021/acs.jmedchem.5b00511
None NON-PROTEIN TARGET IC50 2500000.0 nM 10.1021/jm00212a010
None NON-PROTEIN TARGET IC50 nan nM 10.1016/j.bmcl.2005.03.021
None NON-PROTEIN TARGET IC50 nan None 10.1016/j.ejmech.2016.07.027
None NON-PROTEIN TARGET ID50 8.3 umol.kg-1 10.1021/jm0408013
None NON-PROTEIN TARGET Inhibition 75.0 % 10.1016/j.ejmech.2022.114408
None NON-PROTEIN TARGET Inhibition nan % 10.1016/j.ejmech.2018.10.061
None NON-PROTEIN TARGET Inhibition nan % 10.1021/jm00212a010
None NON-PROTEIN TARGET MSD 30.0 day 10.1016/j.ejmech.2016.07.055
None NON-PROTEIN TARGET Potency 188.2 nM None
None NON-PROTEIN TARGET Ratio 10.0 None 10.1021/jm201108k
None NON-PROTEIN TARGET Ratio 150.0 None 10.1128/aac.01122-10
None NON-PROTEIN TARGET Ratio 1778.0 None 10.1021/jm0302086
None NON-PROTEIN TARGET Ratio EC50 nan None 10.1016/j.bmcl.2014.09.061
None NON-PROTEIN TARGET Ratio IC50 189.0 None 10.1016/j.ejmech.2013.04.066
None NON-PROTEIN TARGET Selectivity 246.0 None 10.1021/jm990131e
None NON-PROTEIN TARGET Selectivity 1778.0 None 10.1021/jm990131e
None NON-PROTEIN TARGET Selectivity Index 16.0 None 10.1021/np9002564
None NON-PROTEIN TARGET Selectivity Index 80.0 None 10.1021/np9002564
None NON-PROTEIN TARGET Survival 5.0 None 10.1021/jm010374i
None No relevant target IC50 0.14 equiv 10.1016/j.bmc.2015.01.031
None No relevant target IC50 0.17 mMequiv 10.1016/j.bmc.2014.05.024
None No relevant target IC50 1.23 equiv 10.1021/acs.jmedchem.5b01374
None No relevant target IC50 1.36 equiv 10.1039/C5MD00115C
None No relevant target IC50 1.9 equiv 10.1016/j.bmcl.2014.06.012
None No relevant target IC50 1.91 equiv 10.1016/j.bmc.2016.06.003
None No relevant target IC50 3.01 equiv 10.1016/j.bmc.2016.06.003
None No relevant target IC50 18200.0 nM 10.1016/j.ejmech.2013.08.046
None No relevant target IC50 27870.0 nM 10.1016/j.ejmech.2014.11.022
None No relevant target IC50 28200.0 nM 10.1016/j.bmc.2015.02.007
None No relevant target IC50 80000.0 nM 10.1039/C0MD00267D
None No relevant target IC50 1890000.0 nM 10.1007/s00044-008-9092-5
None No relevant target IC50 nan None 10.1016/j.bmc.2015.07.051
None No relevant target Inhibition 4.0 % 10.1016/j.ejmech.2015.02.011
None No relevant target Inhibition 87.1 % 10.1016/j.ejmech.2014.01.023
None No relevant target Inhibition 94.0 % 10.1016/j.bmc.2014.12.018
None No relevant target Inhibition 98.57 % 10.1016/j.bmc.2015.05.040
None No relevant target Inhibition nan % 10.1016/j.bmc.2015.05.009
None No relevant target LogD -3.44 None 10.1016/j.ejmech.2014.04.076
None No relevant target LogD -1.2 None 10.1016/j.bmc.2015.02.007
None No relevant target LogD -1.2 None 10.1021/jm060259d
None No relevant target LogD -1.2 None 10.1021/jm9018383
None No relevant target LogD 0.06 None 10.1021/jm8012757
None No relevant target LogD 0.17 None 10.1021/jm011046l
None No relevant target LogD 0.33 None 10.1021/jm0000564
None No relevant target LogD 0.4 None 10.1021/jm200149e
None No relevant target LogD 0.85 None 10.1016/j.bmc.2015.02.007
None No relevant target LogD 0.85 None 10.1021/jm060259d
None No relevant target LogD 0.85 None 10.1021/jm9018383
None No relevant target LogD 0.89 None 10.1016/j.bmc.2012.07.040
None No relevant target LogD 0.9 None 10.1016/j.bmc.2010.08.001
None No relevant target LogD 0.9 None 10.1128/aac.00536-09
None No relevant target LogD 0.92 None 10.1016/j.ejmech.2014.04.076
None No relevant target LogD 2.0 None 10.1021/jm200149e
None No relevant target LogD 4.3 None 10.1016/j.ejmech.2012.07.037
None No relevant target LogD5.0 0.51 None 10.1021/jm020960r
None No relevant target LogD5.0 nan None 10.1021/jm0310840
None No relevant target LogD7.4 0.93 None 10.1021/jm020960r
None No relevant target LogD7.4 1.23 None 10.1021/jm040760a
None No relevant target LogD7.4 nan None 10.1021/jm0310840
None No relevant target log K 5.52 None 10.1016/j.bmc.2014.05.024
None No relevant target LogP 3.73 None 10.1021/jm8012757
None No relevant target LogP 3.93 None 10.1021/acsmedchemlett.0c00196
None No relevant target LogP 4.61 None 10.1021/jm801441s
None No relevant target LogP 4.63 None 10.1021/jm070524a
None No relevant target LogP 4.69 None 10.1021/jm801441s
None No relevant target LogP 4.72 None 10.1021/jm011046l
None No relevant target LogP 4.73 None 10.1016/j.bmc.2010.08.001
None No relevant target LogP 4.73 None 10.1128/aac.00536-09
None No relevant target LogP 4.89 None 10.1016/j.bmc.2012.07.040
None No relevant target LogP nan None 10.1016/j.bmc.2012.11.009
None No relevant target Log S -4.06 None 10.1016/j.ejmech.2013.09.008
None No relevant target pKa 8.1 None 10.1016/j.bmc.2009.10.005
None No relevant target pKa 8.38 None 10.1016/j.bmc.2012.10.019
None No relevant target pKa 8.4 None 10.1021/jm2009698
None No relevant target pKa 8.41 None 10.1128/aac.00288-07
None No relevant target pKa 8.5 None 10.1021/jm400656s
None No relevant target pKa 9.9 None 10.1021/jm0000564
None No relevant target pKa 9.94 None 10.1021/jm040760a
None No relevant target pKa 9.94 None 10.1021/jm070524a
None No relevant target pKa 10.27 None 10.1021/jm011046l
None No relevant target pKa 10.8 None 10.1021/jm2009698
None No relevant target Ratio 0.8684 None 10.1021/jm8012757
None No relevant target Ratio 7.9 None 10.1016/j.bmc.2010.08.001
None No relevant target Ratio 7.9 None 10.1128/aac.00536-09
None No relevant target Ratio 8.25 None 10.1016/j.ejmech.2014.04.076
None No relevant target Solubility 100.0 ug.mL-1 10.1021/jm200149e
None No relevant target Solubility 30000.0 nM 10.1016/j.ejmech.2012.07.037
None NSC CC50 94950.0 nM 10.1021/acs.jmedchem.9b00775
None Nucleic Acid Activity 10.0 % 10.1021/jm060736s
None Nucleic Acid Activity 23.0 % 10.1021/jm060736s
None Nucleic Acid Activity 50.0 % 10.1021/jm060736s
None Nucleic Acid Activity 75.0 % 10.1021/jm060736s
None Nucleic Acid Activity nan None 10.1021/jm060736s
None Nucleic Acid IC50 nan None 10.1021/jm801490z
None Nucleic Acid Kd 7500.0 nM 10.1021/jm9018383
None Nucleic Acid Kd 9000.0 nM 10.1021/jm9018383
None Nucleic Acid Log Kd 4.25 None 10.1021/jm00370a007
None Nucleic Acid log Ks nan None 10.1016/j.ejmech.2012.03.007
None Nucleic Acid Tm 46.6 degrees C 10.1021/jm9018383
None Nucleic Acid Tm 46.9 degrees C 10.1021/jm9018383
None Nucleic Acid Tm 47.0 degrees C 10.1021/jm9018383
None Nucleic Acid Tm 73.2 degrees C 10.1021/jm9018383
None Nucleic Acid Tm 73.7 degrees C 10.1021/jm9018383
None Nucleic Acid Tm 74.65 degrees C 10.1021/jm9018383
None Phospholipidosis Maximum test concentration that did not exhibit cytotoxicity 10.0 uM None
None Phospholipidosis Phospholipidosis nan None 10.1021/ci6004542
None Phospholipidosis Phospholipidosis nan None 10.1021/mp100103e
None Phospholipidosis Phospholipidosis nan None 10.1080/15376510701857262
None Phospholipidosis Phospholipidosis as % of positive control 22.8 % None
None Radical scavenging activity Activity 4.06 % 10.1016/j.ejmech.2011.02.004
None Unchecked Activity 1.0 % 10.1039/d2md00392a
None Unchecked Activity 65.0 % 10.1016/j.bmcl.2012.07.028
None Unchecked Activity nan None 10.1016/j.bmc.2010.09.041
None Unchecked Activity nan None 10.1016/j.bmc.2020.115732
None Unchecked Activity nan None 10.1016/j.bmc.2021.116306
None Unchecked Activity nan None 10.1016/j.bmcl.2008.09.030
None Unchecked Activity nan None 10.1016/j.bmcl.2011.11.014
None Unchecked Activity nan None 10.1016/j.bmcl.2020.127336
None Unchecked Activity nan None 10.1021/acs.jmedchem.0c00894
None Unchecked Activity nan None 10.1021/acs.jmedchem.7b01417
None Unchecked Activity nan None 10.1021/acsmedchemlett.1c00589
None Unchecked Activity nan None 10.1021/acsmedchemlett.8b00222
None Unchecked Activity nan None 10.1021/jm011046l
None Unchecked Activity nan None 10.1128/aac.00288-07
None Unchecked Activity nan None 10.1128/aac.00536-09
None Unchecked CC50 19380.0 nM 10.1016/j.ejmech.2021.113271
None Unchecked CC50 89000.0 nM 10.1021/acs.jnatprod.7b00233
None Unchecked CC50 94950.0 nM 10.1021/acs.jmedchem.9b00775
None Unchecked CC50 137490.0 nM 10.1016/j.ejmech.2018.04.038
None Unchecked CC50 nan None 10.1016/j.bmcl.2017.02.049
None Unchecked Drug uptake nan None 10.1021/acs.jmedchem.7b00124
None Unchecked EC50 1.8 mg kg-1 day-1 10.1021/jm010374i
None Unchecked EC50 18.0 nM 10.1021/jm010448q
None Unchecked EC50 110.0 nM 10.1021/acs.jmedchem.1c00300
None Unchecked EC50 800.0 nM 10.1021/acsmedchemlett.2c00123
None Unchecked EC50 907000.0 nM 10.1016/j.bmc.2019.01.044
None Unchecked ED50 1.5 mg.kg-1 10.1021/jm990002y
None Unchecked ED50 2.4 mg.kg-1 10.1021/jm990002y
None Unchecked ED90 3.3 mg kg-1 10.1021/jm990002y
None Unchecked ED90 5.0 mg kg-1 10.1021/jm990002y
None Unchecked Hepatotoxicity (acute) 8.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 4.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 0.04 ug.mL-1 10.1016/s0960-894x(02)00350-5
None Unchecked IC50 0.17 mMequiv 10.1016/j.ejmech.2010.07.068
None Unchecked IC50 1.09 equiv 10.1021/jm100938u
None Unchecked IC50 1.27 mol 10.1016/j.bmc.2010.08.001
None Unchecked IC50 1.5 None 10.1021/jm9018383
None Unchecked IC50 1.9 equiv 10.1021/ml4001084
None Unchecked IC50 1.9 nM 10.1021/jm2009698
None Unchecked IC50 1.91 equiv 10.1016/j.bmc.2010.10.009
None Unchecked IC50 1.94 molar ratio 10.1016/j.bmc.2012.07.040
None Unchecked IC50 3.65 ug 10.1016/j.ejmech.2010.12.003
None Unchecked IC50 28.0 nM 10.1021/jm901300d
None Unchecked IC50 40.0 ug.mL-1 10.1016/j.bmc.2014.01.036
None Unchecked IC50 46.0 nM 10.1021/acsmedchemlett.8b00222
None Unchecked IC50 69.4 nM 10.1016/j.bmcl.2010.02.017
None Unchecked IC50 270.0 nM 10.1021/acs.jmedchem.0c01511
None Unchecked IC50 1480.0 nM 10.1016/j.ejmech.2017.10.051
None Unchecked IC50 1630.0 nM 10.1021/jm400282d
None Unchecked IC50 1910.0 nM 10.1021/jm400282d
None Unchecked IC50 6600.0 nM 10.1021/jm400246e
None Unchecked IC50 8100.0 ug.mL-1 10.1021/np8004612
None Unchecked IC50 9500.0 nM 10.1128/aac.01304-08
None Unchecked IC50 10000.0 nM 10.1021/acs.jmedchem.1c01036
None Unchecked IC50 10100.0 nM 10.1016/j.bmc.2015.01.036
None Unchecked IC50 16000.0 nM 10.1021/jm701478a
None Unchecked IC50 18000.0 nM 10.1016/j.ejmech.2012.03.007
None Unchecked IC50 18400.0 nM 10.1016/j.ejmech.2013.03.072
None Unchecked IC50 22290.0 nM 10.1016/j.bmc.2011.06.025
None Unchecked IC50 24400.0 nM 10.1021/jm400282d
None Unchecked IC50 24970.0 nM 10.1016/j.ejmech.2011.02.004
None Unchecked IC50 27200.0 nM 10.1016/j.bmcl.2017.03.005
None Unchecked IC50 30000.0 nM 10.1016/j.bmc.2014.03.030
None Unchecked IC50 30000.0 nM 10.1021/jm400656s
None Unchecked IC50 33000.0 nM 10.1016/j.bmc.2012.03.042
None Unchecked IC50 35000.0 nM 10.1021/jm701478a
None Unchecked IC50 43800.0 nM 10.1021/jm400282d
None Unchecked IC50 45000.0 nM 10.1021/jm400282d
None Unchecked IC50 49000.0 nM 10.1016/j.bmc.2012.03.042
None Unchecked IC50 50000.0 nM 10.1021/jm400282d
None Unchecked IC50 57000.0 nM 10.1016/j.bmcl.2009.08.013
None Unchecked IC50 64000.0 nM 10.1016/j.ejmech.2017.11.075
None Unchecked IC50 70000.0 nM 10.1016/j.ejmech.2007.03.008
None Unchecked IC50 73760.0 nM 10.1016/j.ejmech.2013.08.004
None Unchecked IC50 80000.0 nM 10.1016/j.bmc.2010.11.036
None Unchecked IC50 80000.0 nM 10.1016/j.ejmech.2012.03.019
None Unchecked IC50 80000.0 nM 10.1021/jm030038x
None Unchecked IC50 80000.0 nM 10.1021/jm400282d
None Unchecked IC50 117050.0 nM 10.1021/jm400282d
None Unchecked IC50 200000.0 nM 10.1016/j.bmcl.2004.05.031
None Unchecked IC50 252000.0 nM 10.1021/jm400282d
None Unchecked IC50 315000.0 nM 10.1021/acsmedchemlett.6b00416
None Unchecked IC50 374100.0 nM 10.1021/jm400282d
None Unchecked IC50 400000.0 nM 10.1021/jm400282d
None Unchecked IC50 415000.0 nM 10.1021/np100737q
None Unchecked IC50 600000.0 nM 10.1021/np100737q
None Unchecked IC50 900000.0 nM 10.1016/j.bmc.2009.10.005
None Unchecked IC50 1460000.0 nM 10.1016/j.ejmech.2015.03.011
None Unchecked IC50 nan None 10.1016/j.bmcl.2010.06.007
None Unchecked IC50 nan None 10.1016/j.bmcl.2011.02.008
None Unchecked IC50 nan None 10.1016/j.bmcl.2016.01.052
None Unchecked IC50 nan None 10.1016/j.ejmech.2009.02.024
None Unchecked IC50 nan None 10.1016/j.ejmech.2012.05.022
None Unchecked IC50 nan None 10.1016/j.ejmech.2013.08.037
None Unchecked IC50 nan None 10.1021/acsmedchemlett.8b00371
None Unchecked IC50 nan None 10.1021/jm201216y
None Unchecked IC50 nan None 10.1021/np0496284
None Unchecked IC50 nan None 10.1021/np8000909
None Unchecked IC50 nan None 10.1038/nchembio.87
None Unchecked IFI 1.163 % 10.1073/pnas.0802982105
None Unchecked INH 24.0 uM 10.1021/jm1006484
None Unchecked Inhibition 13.2 % 10.1016/j.bmcl.2020.127336
None Unchecked Inhibition 46.0 % 10.1016/0960-894X(95)00577-G
None Unchecked Inhibition 47.0 % 10.1016/0960-894X(95)00577-G
None Unchecked Inhibition 48.8 % 10.1016/j.ejmech.2017.07.077
None Unchecked Inhibition 53.5 % 10.1016/j.ejmech.2012.12.019
None Unchecked Inhibition 65.4 % 10.1021/acs.jmedchem.7b01417
None Unchecked Inhibition 75.0 % 10.1021/jm301654b
None Unchecked Inhibition 87.0 % 10.1016/j.bmc.2017.02.025
None Unchecked Inhibition 94.19 % 10.1016/j.bmc.2011.01.050
None Unchecked Inhibition 98.0 % 10.1016/j.ejmech.2013.05.046
None Unchecked Inhibition 98.52 % 10.1016/j.bmc.2017.12.022
None Unchecked Inhibition 98.57 % 10.1016/j.ejmech.2017.10.051
None Unchecked Inhibition nan % 10.1016/j.bmcl.2016.01.052
None Unchecked Inhibition nan % 10.1016/j.bmcl.2016.12.040
None Unchecked Inhibition nan % 10.1021/acs.jmedchem.0c01744
None Unchecked Inhibition nan % 10.1021/acs.jmedchem.0c02022
None Unchecked Inhibition nan % 10.1021/acs.jmedchem.7b01417
None Unchecked Inhibition nan % 10.1021/acs.jmedchem.8b01961
None Unchecked Inhibition nan % 10.1021/jm900629w
None Unchecked K 4.9 /M 10.1016/j.bmcl.2010.08.043
None Unchecked Ka 0.3 10^5/M 10.1016/j.bmc.2008.01.053
None Unchecked Ka 0.54 M 10.1021/jm030038x
None Unchecked Ka 1.75 10'5/M 10.1021/jm701478a
None Unchecked Ka 3.24 10'5/M 10.1128/aac.00288-07
None Unchecked Ka 4.0 10^5/M 10.1016/j.bmc.2007.10.083
None Unchecked Kd 5400.0 nM 10.1016/j.bmc.2009.10.005
None Unchecked Ki nan None 10.1016/j.bmcl.2012.07.069
None Unchecked Ki nan None 10.1021/jm900629w
None Unchecked Ki nan None 10.1021/jm900946n
None Unchecked Ki nan None 10.1021/ml300419r
None Unchecked log K 5.52 None 10.1016/j.bmc.2014.09.009
None Unchecked log K nan None 10.1016/j.ejmech.2013.05.046
None Unchecked Log K 5.3 None 10.1021/jm0408013
None Unchecked Log K 5.4 None 10.1021/jm0408013
None Unchecked Log K 5.8 None 10.1021/jm0408013
None Unchecked logKA 4.8 None 10.1021/jm400246e
None Unchecked logKA 5.2 None 10.1021/jm701478a
None Unchecked log Ks 5.52 None 10.1016/j.ejmech.2010.07.068
None Unchecked MDL50 457.0 uM 10.1016/j.bmc.2020.115832
None Unchecked MIC 125000.0 nM 10.1016/j.ejmech.2014.04.076
None Unchecked MIC 125000.0 nM 10.1021/jm4011466
None Unchecked Potency 132.1 nM None
None Unchecked Potency 742.7 nM None
None Unchecked Potency 7304.8 nM None
None Unchecked Ratio 1.36 None 10.1016/j.bmcl.2012.07.069
None Unchecked Ratio 11.0 None 10.1016/j.bmc.2007.10.031
None Unchecked Ratio 12.9 None 10.1021/acsmedchemlett.2c00531
None Unchecked Ratio 20.0 None 10.1016/j.bmc.2008.11.050
None Unchecked Ratio 32.0 None 10.1021/jm070201e
None Unchecked Ratio 61.1 None 10.1021/jm0310840
None Unchecked Ratio 200.0 None 10.1016/j.ejmech.2010.08.049
None Unchecked Ratio 209.0 None 10.1021/acs.jmedchem.6b00719
None Unchecked Ratio 501.0 None 10.1016/j.bmc.2008.11.050
None Unchecked Ratio 2285.0 None 10.1016/j.bmc.2020.115832
None Unchecked Ratio 8983.0 None 10.1016/j.bmcl.2009.03.026
None Unchecked Ratio nan None 10.1021/acsmedchemlett.8b00592
None Unchecked Ratio nan None 10.1021/jm0310840
None Unchecked Ratio CC50/EC50 5.32 None 10.1128/aac.00843-07
None Unchecked Ratio CC50/EC50 6.0 None 10.1021/acs.jnatprod.5b00116
None Unchecked Ratio CC50/EC50 6.4 None 10.1021/np500271u
None Unchecked Ratio CC50/EC50 8.0 None 10.1021/acs.jnatprod.8b00800
None Unchecked Ratio CC50/EC50 8.1 None 10.1016/j.bmc.2018.01.002
None Unchecked Ratio CC50/EC50 8.1 None 10.1016/j.ejmech.2018.02.054
None Unchecked Ratio CC50/EC50 8.1 None 10.1021/acs.jnatprod.5b00116
None Unchecked Ratio CC50/EC50 8.1 None 10.1021/acs.jnatprod.7b00233
None Unchecked Ratio CC50/EC50 8.1 None 10.1021/np300637t
None Unchecked Ratio CC50/EC50 8.1 None 10.1021/np500271u
None Unchecked Ratio CC50/EC50 8.9 None 10.1021/acs.jnatprod.5b00073
None Unchecked Ratio CC50/EC50 8.9 None 10.1021/np500271u
None Unchecked Ratio CC50/EC50 15.0 None 10.1021/acs.jmedchem.0c00626
None Unchecked Ratio CC50/EC50 16.11 None 10.1016/j.ejmech.2017.02.012
None Unchecked Ratio CC50/EC50 30.0 None 10.1021/acs.jmedchem.0c00626
None Unchecked Ratio CC50/EC50 34.0 None 10.1016/j.ejmech.2016.12.058
None Unchecked Ratio CC50/EC50 34.0 None 10.1016/j.ejmech.2017.01.007
None Unchecked Ratio CC50/EC50 60.0 None 10.1021/acs.jmedchem.0c00626
None Unchecked Ratio CC50/EC50 88.0 None 10.1021/acs.jmedchem.0c00626
None Unchecked Ratio CC50/EC50 450.0 None 10.1021/jm5009693
None Unchecked Ratio CC50/EC50 nan None 10.1021/acs.jnatprod.5b00073
None Unchecked Ratio CC50/IC50 0.97 None 10.1016/j.ejmech.2015.03.011
None Unchecked Ratio CC50/IC50 3.1 None 10.1016/j.bmcl.2020.127667
None Unchecked Ratio CC50/IC50 4.4 None 10.1016/j.bmcl.2011.05.125
None Unchecked Ratio CC50/IC50 8.0 None 10.1016/j.bmc.2012.06.038
None Unchecked Ratio CC50/IC50 50.0 None 10.1016/j.ejmech.2014.06.014
None Unchecked Ratio CC50/IC50 50.0 None 10.1016/j.ejmech.2016.04.059
None Unchecked Ratio CC50/IC50 50.0 None 10.1016/j.ejmech.2016.09.029
None Unchecked Ratio CC50/IC50 60.0 None 10.1016/j.bmcl.2011.06.113
None Unchecked Ratio CC50/IC50 60.0 None 10.1016/j.ejmech.2012.07.034
None Unchecked Ratio CC50/IC50 60.0 None 10.1016/j.ejmech.2014.07.113
None Unchecked Ratio CC50/IC50 60.0 None 10.1016/j.ejmech.2015.03.011
None Unchecked Ratio CC50/IC50 75.0 None 10.1016/j.ejmech.2011.06.021
None Unchecked Ratio CC50/IC50 120.0 None 10.1016/j.bmc.2014.09.040
None Unchecked Ratio CC50/IC50 136.0 None 10.1039/C1MD00127B
None Unchecked Ratio CC50/IC50 140.8 None 10.1016/j.bmc.2012.06.038
None Unchecked Ratio CC50/IC50 151.0 None 10.1016/j.ejmech.2014.05.037
None Unchecked Ratio CC50/IC50 167.0 None 10.1016/j.ejmech.2014.02.038
None Unchecked Ratio CC50/IC50 167.0 None 10.1016/j.ejmech.2014.03.059
None Unchecked Ratio CC50/IC50 167.0 None 10.1021/jm901300d
None Unchecked Ratio CC50/IC50 175.0 None 10.1016/j.ejmech.2007.03.008
None Unchecked Ratio CC50/IC50 217.0 None 10.1016/j.bmc.2007.05.038
None Unchecked Ratio CC50/IC50 365.66 None 10.1016/j.ejmech.2021.113271
None Unchecked Ratio CC50/IC50 366.0 None 10.1016/j.ejmech.2014.05.037
None Unchecked Ratio CC50/IC50 397.0 None 10.1016/j.ejmech.2007.11.003
None Unchecked Ratio CC50/IC50 492.13 None 10.1016/j.bmcl.2015.08.030
None Unchecked Ratio CC50/IC50 513.0 None 10.1016/j.ejmech.2017.03.010
None Unchecked Ratio CC50/IC50 530.0 None 10.1021/jm300588j
None Unchecked Ratio CC50/IC50 578.68 None 10.1021/ml500211c
None Unchecked Ratio CC50/IC50 584.0 None 10.1016/j.bmc.2007.05.038
None Unchecked Ratio CC50/IC50 646.3 None 10.1016/j.ejmech.2012.12.010
None Unchecked Ratio CC50/IC50 663.86 None 10.1016/j.ejmech.2018.08.063
None Unchecked Ratio CC50/IC50 750.0 None 10.1016/j.ejmech.2015.03.011
None Unchecked Ratio CC50/IC50 982.5 None 10.1016/j.ejmech.2017.12.051
None Unchecked Ratio CC50/IC50 1000.0 None 10.1016/j.bmcl.2015.04.014
None Unchecked Ratio CC50/IC50 1000.0 None 10.1016/j.ejmech.2018.06.042
None Unchecked Ratio CC50/IC50 1000.0 None 10.1016/j.ejmech.2018.11.008
None Unchecked Ratio CC50/IC50 1146.0 None 10.1016/j.ejmech.2018.04.038
None Unchecked Ratio CC50/IC50 1257.0 None 10.1021/jm901300d
None Unchecked Ratio CC50/IC50 1709.0 None 10.1021/acs.jmedchem.8b01310
None Unchecked Ratio CC50/IC50 1900.0 None 10.1016/j.bmc.2014.09.040
None Unchecked Ratio CC50/IC50 3166.0 None 10.1016/j.bmc.2014.09.040
None Unchecked Ratio CC50/IC50 3333.3 None 10.1016/j.bmc.2012.06.038
None Unchecked Ratio CC50/IC50 4263.0 None 10.1016/j.ejmech.2013.11.022
None Unchecked Ratio CC50/IC50 8983.0 None 10.1016/j.bmc.2009.05.075
None Unchecked Ratio CC50/IC50 8983.0 None 10.1016/j.bmc.2014.05.024
None Unchecked Ratio CC50/IC50 8983.0 None 10.1016/j.ejmech.2013.01.017
None Unchecked Ratio CC50/IC50 8983.0 None 10.1016/j.ejmech.2013.05.023
None Unchecked Ratio CC50/IC50 13393.0 None 10.1021/jm300588j
None Unchecked Ratio CC50/IC50 15000.0 None 10.1016/j.ejmech.2017.07.052
None Unchecked Ratio CC50/IC50 22890.0 None 10.1016/j.ejmech.2012.12.019
None Unchecked Ratio CC50/IC50 25000.0 None 10.1016/j.bmcl.2015.08.030
None Unchecked Ratio CC50/IC50 30612.0 None 10.1016/j.bmcl.2012.10.101
None Unchecked Ratio CC50/IC50 30612.0 None 10.1016/j.ejmech.2017.04.063
None Unchecked Ratio CC50/IC50 32285.0 None 10.1016/j.ejmech.2017.03.010
None Unchecked Ratio CC50/IC50 58833.3 None 10.1021/ml500211c
None Unchecked Ratio CC50/IC50 71428.0 None 10.1016/j.ejmech.2018.11.008
None Unchecked Ratio CC50/IC50 71428.6 None 10.1016/j.ejmech.2018.06.042
None Unchecked Ratio CC50/IC50 77917.0 None 10.1016/j.bmc.2007.05.038
None Unchecked Ratio CC50/IC50 nan None 10.1016/j.bmcl.2017.02.049
None Unchecked Ratio EC50 3.78 None 10.1016/j.ejmech.2018.01.082
None Unchecked Ratio EC50 9.8 None 10.1021/acs.jmedchem.0c00858
None Unchecked Ratio EC50 33.0 None 10.1021/jm200636z
None Unchecked Ratio EC50 60.0 None 10.1021/acs.jmedchem.0c00858
None Unchecked Ratio EC50 833.0 None 10.1021/jm200636z
None Unchecked Ratio EC50 nan None 10.1016/j.ejmech.2015.07.047
None Unchecked Ratio ED50 158.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 205.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 246.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 319.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 451.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 498.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 631.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 649.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 1550.0 None 10.1021/np50098a017
None Unchecked Ratio ED50 1550.0 None 10.1021/np50099a005
None Unchecked Ratio ED50 2000.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 2600.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 3120.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 4040.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 5720.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 6320.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 6960.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 8000.0 None 10.1021/np50091a005
None Unchecked Ratio ED50 13380.0 None 10.1021/np50098a017
None Unchecked Ratio ED50 13380.0 None 10.1021/np50099a005
None Unchecked RatioGI50 6.0 None 10.1016/j.bmc.2012.11.009
None Unchecked RatioGI50 8.0 None 10.1016/j.bmc.2012.11.009
None Unchecked RatioGI50 35.0 None 10.1016/j.bmc.2012.11.009
None Unchecked Ratio IC50 0.05 None 10.1016/j.ejmech.2021.113981
None Unchecked Ratio IC50 0.19 None 10.1007/s00044-011-9694-1
None Unchecked Ratio IC50 0.3 None 10.1016/j.ejmech.2021.113685
None Unchecked Ratio IC50 0.4 None 10.1016/j.ejmech.2021.113981
None Unchecked Ratio IC50 1.0 None 10.1016/j.bmcl.2018.03.026
None Unchecked Ratio IC50 1.0 None 10.1021/jm00212a010
None Unchecked Ratio IC50 1.2 None 10.1021/ml500348p
None Unchecked Ratio IC50 1.8 None 10.1016/j.ejmech.2018.11.021
None Unchecked Ratio IC50 1.91 None 10.1021/jm200149e
None Unchecked Ratio IC50 1.96 None 10.1007/s00044-011-9694-1
None Unchecked Ratio IC50 4.01 None 10.1016/j.bmcl.2017.12.060
None Unchecked Ratio IC50 4.2 None 10.1016/j.ejmech.2018.06.025
None Unchecked Ratio IC50 4.3 None 10.1021/jm201216y
None Unchecked Ratio IC50 4.6 None 10.1016/j.ejmech.2018.09.018
None Unchecked Ratio IC50 5.4 None 10.1016/j.bmc.2008.09.038
None Unchecked Ratio IC50 6.49 None 10.1016/j.ejmech.2009.02.024
None Unchecked Ratio IC50 8.2 None 10.1016/j.ejmech.2014.11.016
None Unchecked Ratio IC50 8.22 None 10.1021/acsmedchemlett.8b00496
None Unchecked Ratio IC50 8.8 None 10.1016/j.ejmech.2021.113518
None Unchecked Ratio IC50 9.4 None 10.1016/j.ejmech.2018.09.060
None Unchecked Ratio IC50 9.8 None 10.1021/acs.jnatprod.8b00956
None Unchecked Ratio IC50 10.0 None 10.1016/j.ejmech.2009.02.024
None Unchecked Ratio IC50 10.48 None 10.1016/j.ejmech.2014.10.061
None Unchecked Ratio IC50 11.0 None 10.1016/j.ejmech.2018.06.025
None Unchecked Ratio IC50 11.6 None 10.1016/j.bmc.2008.09.038
None Unchecked Ratio IC50 12.5 None 10.1021/jm201216y
None Unchecked Ratio IC50 12.7 None 10.1016/j.bmc.2008.11.009
None Unchecked Ratio IC50 14.0 None 10.1016/j.ejmech.2019.111755
None Unchecked Ratio IC50 14.0 None 10.1021/acsmedchemlett.6b00416
None Unchecked Ratio IC50 14.6 None 10.1016/j.bmc.2009.08.003
None Unchecked Ratio IC50 14.84 None 10.1021/jm800737y
None Unchecked Ratio IC50 15.0 None 10.1021/jm500715u
None Unchecked Ratio IC50 15.0 None 10.1021/jm900972u
None Unchecked Ratio IC50 15.4 None 10.1016/j.bmcl.2016.05.024
None Unchecked Ratio IC50 15.46 None 10.1016/j.bmcl.2017.07.039
None Unchecked Ratio IC50 15.5 None 10.1016/j.ejmech.2009.02.024
None Unchecked Ratio IC50 15.6 None 10.1016/j.ejmech.2016.07.027
None Unchecked Ratio IC50 16.0 None 10.1016/j.bmc.2014.09.040
None Unchecked Ratio IC50 17.7 None 10.1016/j.bmc.2008.05.068
None Unchecked Ratio IC50 20.0 None 10.1016/j.bmcl.2012.11.004
None Unchecked Ratio IC50 20.0 None 10.1016/j.ejmech.2022.114408
None Unchecked Ratio IC50 20.0 None 10.1021/np8000909
None Unchecked Ratio IC50 20.2 None 10.1016/j.ejmech.2019.06.069
None Unchecked Ratio IC50 21.25 None 10.1039/C3MD20377H
None Unchecked Ratio IC50 21.6 None 10.1021/acs.jnatprod.6b00967
None Unchecked Ratio IC50 22.0 None 10.1021/acs.jnatprod.0c00929
None Unchecked Ratio IC50 22.2 None 10.1016/j.bmc.2012.07.040
None Unchecked Ratio IC50 22.3 None 10.1016/j.bmc.2014.03.030
None Unchecked Ratio IC50 23.3 None 10.1016/j.bmcl.2016.05.024
None Unchecked Ratio IC50 24.8 None 10.1021/acs.jnatprod.2c01041
None Unchecked Ratio IC50 25.0 None 10.1016/j.bmcl.2016.09.038
None Unchecked Ratio IC50 26.0 None 10.1016/j.bmc.2014.09.040
None Unchecked Ratio IC50 28.81 None 10.1016/j.ejmech.2017.02.024
None Unchecked Ratio IC50 29.58 None 10.1016/j.ejmech.2016.11.057
None Unchecked Ratio IC50 30.0 None 10.1016/j.ejmech.2011.04.002
None Unchecked Ratio IC50 31.54 None 10.1016/j.ejmech.2017.02.024
None Unchecked Ratio IC50 32.35 None 10.1021/jm800737y
None Unchecked Ratio IC50 33.1 None 10.1016/j.ejmech.2022.114408
None Unchecked Ratio IC50 34.0 None 10.1021/np000436s
None Unchecked Ratio IC50 34.0 None 10.1021/np0102861
None Unchecked Ratio IC50 34.0 None 10.1021/np030045o
None Unchecked Ratio IC50 34.6 None 10.1016/j.ejmech.2017.03.007
None Unchecked Ratio IC50 35.0 None 10.1021/acs.jmedchem.0c01411
None Unchecked Ratio IC50 35.7 None 10.1016/j.ejmech.2022.114408
None Unchecked Ratio IC50 36.5 None 10.1016/j.ejmech.2018.11.021
None Unchecked Ratio IC50 38.46 None 10.1016/j.bmcl.2018.03.026
None Unchecked Ratio IC50 38.5 None 10.1016/j.bmc.2016.12.006
None Unchecked Ratio IC50 42.0 None 10.1016/j.bmc.2009.06.020
None Unchecked Ratio IC50 42.0 None 10.1016/j.bmcl.2007.12.069
None Unchecked Ratio IC50 42.0 None 10.1016/j.bmcl.2009.01.103
None Unchecked Ratio IC50 42.0 None 10.1021/acs.jmedchem.1c00354
None Unchecked Ratio IC50 42.9 None 10.1016/j.bmc.2009.05.022
None Unchecked Ratio IC50 42.9 None 10.1016/j.bmcl.2007.10.027
None Unchecked Ratio IC50 43.0 None 10.1016/j.bmc.2009.10.005
None Unchecked Ratio IC50 43.0 None 10.1016/j.ejmech.2009.11.005
None Unchecked Ratio IC50 45.0 None 10.1016/j.bmc.2009.10.005
None Unchecked Ratio IC50 45.7 None 10.1016/j.bmc.2009.05.022
None Unchecked Ratio IC50 46.0 None 10.1016/j.ejmech.2009.11.005
None Unchecked Ratio IC50 50.52 None 10.1016/j.ejmech.2007.11.024
None Unchecked Ratio IC50 51.0 None 10.1016/j.bmc.2009.10.005
None Unchecked Ratio IC50 54.49 None 10.1016/j.ejmech.2014.10.061
None Unchecked Ratio IC50 56.0 None 10.1021/np030086k
None Unchecked Ratio IC50 56.0 None 10.1021/np030524n
None Unchecked Ratio IC50 57.1 None 10.1016/j.bmcl.2007.10.027
None Unchecked Ratio IC50 57.1 None 10.1016/j.ejmech.2009.10.022
None Unchecked Ratio IC50 60.0 None 10.1021/np8000909
None Unchecked Ratio IC50 62.85 None 10.1016/j.ejmech.2017.03.010
None Unchecked Ratio IC50 69.8 None 10.1016/j.ejmech.2015.06.024
None Unchecked Ratio IC50 100.0 None 10.1016/j.bmc.2008.05.079
None Unchecked Ratio IC50 100.0 None 10.1021/acsmedchemlett.8b00592
None Unchecked Ratio IC50 101.0 None 10.1016/j.bmcl.2013.02.075
None Unchecked Ratio IC50 118.6 None 10.1021/np020070e
None Unchecked Ratio IC50 119.0 None 10.1016/j.bmc.2014.11.028
None Unchecked Ratio IC50 152.0 None 10.1021/ml3000808
None Unchecked Ratio IC50 160.0 None 10.1016/j.bmcl.2012.11.004
None Unchecked Ratio IC50 161.0 None 10.1016/j.ejmech.2007.11.024
None Unchecked Ratio IC50 161.0 None 10.1021/acs.jnatprod.0c00929
None Unchecked Ratio IC50 169.3 None 10.1039/C8MD00098K
None Unchecked Ratio IC50 193.0 None 10.1016/j.bmcl.2018.03.026
None Unchecked Ratio IC50 200.0 None 10.1016/j.ejmech.2018.06.025
None Unchecked Ratio IC50 200.0 None 10.1021/np8000909
None Unchecked Ratio IC50 221.5 None 10.1016/j.bmc.2008.09.038
None Unchecked Ratio IC50 238.0 None 10.1016/j.ejmech.2012.03.019
None Unchecked Ratio IC50 238.0 None 10.1039/C0MD00267D
None Unchecked Ratio IC50 251.0 None 10.1021/np000436s
None Unchecked Ratio IC50 251.0 None 10.1021/np0102861
None Unchecked Ratio IC50 251.0 None 10.1021/np030045o
None Unchecked Ratio IC50 270.0 None 10.1128/aac.00967-06
None Unchecked Ratio IC50 298.0 None 10.1016/j.bmc.2009.06.020
None Unchecked Ratio IC50 298.0 None 10.1016/j.bmcl.2007.12.069
None Unchecked Ratio IC50 298.0 None 10.1016/j.bmcl.2009.01.103
None Unchecked Ratio IC50 300.0 None 10.1016/j.ejmech.2011.04.002
None Unchecked Ratio IC50 310.0 None 10.1016/j.ejmech.2016.11.057
None Unchecked Ratio IC50 326.6 None 10.1016/j.bmcl.2011.08.116
None Unchecked Ratio IC50 347.0 None 10.1021/acsmedchemlett.9b00669
None Unchecked Ratio IC50 353.0 None 10.1021/ml400447v
None Unchecked Ratio IC50 357.0 None 10.1016/j.ejmech.2013.08.037
None Unchecked Ratio IC50 372.0 None 10.1016/j.ejmech.2017.03.007
None Unchecked Ratio IC50 420.21 None 10.1016/j.bmcl.2007.07.049
None Unchecked Ratio IC50 422.0 None 10.1016/j.ejmech.2014.11.016
None Unchecked Ratio IC50 433.0 None 10.1016/j.ejmech.2020.112969
None Unchecked Ratio IC50 474.8 None 10.1016/j.bmc.2008.09.038
None Unchecked Ratio IC50 486.0 None 10.1021/acs.jnatprod.7b00992
None Unchecked Ratio IC50 500.0 None 10.1016/j.bmc.2011.10.037
None Unchecked Ratio IC50 500.0 None 10.1021/np8005953
None Unchecked Ratio IC50 514.0 None 10.1016/j.bmcl.2010.11.081
None Unchecked Ratio IC50 530.0 None 10.1021/np050510c
None Unchecked Ratio IC50 533.3 None 10.1021/acs.jmedchem.8b01464
None Unchecked Ratio IC50 556.0 None 10.1021/np030086k
None Unchecked Ratio IC50 556.0 None 10.1021/np030524n
None Unchecked Ratio IC50 571.42 None 10.1016/j.ejmech.2014.10.061
None Unchecked Ratio IC50 580.0 None 10.1021/np9602325
None Unchecked Ratio IC50 606.0 None 10.1016/j.bmc.2017.02.043
None Unchecked Ratio IC50 606.1 None 10.1016/j.bmc.2016.12.006
None Unchecked Ratio IC50 612.0 None 10.1016/j.bmc.2013.10.050
None Unchecked Ratio IC50 612.0 None 10.1016/j.ejmech.2014.06.022
None Unchecked Ratio IC50 612.0 None 10.1021/jm400508e
None Unchecked Ratio IC50 667.0 None 10.1021/acs.jnatprod.6b00967
None Unchecked Ratio IC50 909.09 None 10.1016/j.ejmech.2017.02.024
None Unchecked Ratio IC50 920.0 None 10.1016/j.bmc.2016.06.003
None Unchecked Ratio IC50 932.5 None 10.1016/j.bmc.2012.09.052
None Unchecked Ratio IC50 944.0 None 10.1021/jm0708634
None Unchecked Ratio IC50 944.0 None 10.1021/jm800918v
None Unchecked Ratio IC50 944.0 None 10.1021/jm801547t
None Unchecked Ratio IC50 944.0 None 10.1021/jm900805v
None Unchecked Ratio IC50 944.0 None 10.1021/jm901178d
None Unchecked Ratio IC50 953.0 None 10.1016/j.ejmech.2018.09.018
None Unchecked Ratio IC50 972.9 None 10.1016/j.ejmech.2015.06.024
None Unchecked Ratio IC50 1000.0 None 10.1016/j.bmc.2008.05.079
None Unchecked Ratio IC50 1000.0 None 10.1016/j.ejmech.2014.05.050
None Unchecked Ratio IC50 1053.0 None 10.1021/np020070e
None Unchecked Ratio IC50 1238.0 None 10.1016/j.bmcl.2013.02.075
None Unchecked Ratio IC50 1250.0 None 10.1016/j.bmc.2009.10.005
None Unchecked Ratio IC50 1257.0 None 10.1016/j.bmc.2009.04.002
None Unchecked Ratio IC50 1257.0 None 10.1016/j.bmc.2010.07.046
None Unchecked Ratio IC50 1257.0 None 10.1016/j.bmc.2013.06.059
None Unchecked Ratio IC50 1257.0 None 10.1016/j.ejmech.2009.09.040
None Unchecked Ratio IC50 1257.0 None 10.1016/j.ejmech.2011.11.022
None Unchecked Ratio IC50 1500.0 None 10.1021/ml3000808
None Unchecked Ratio IC50 1570.0 None 10.1016/j.bmc.2016.06.024
None Unchecked Ratio IC50 1570.0 None 10.1016/j.bmc.2019.03.061
None Unchecked Ratio IC50 1570.0 None 10.1016/j.bmcl.2006.07.057
None Unchecked Ratio IC50 1570.0 None 10.1016/j.bmcl.2015.02.044
None Unchecked Ratio IC50 1571.0 None 10.1016/j.bmc.2007.05.042
None Unchecked Ratio IC50 1571.0 None 10.1016/j.bmc.2008.05.007
None Unchecked Ratio IC50 1690.0 None 10.1016/j.bmcl.2016.04.053
None Unchecked Ratio IC50 1700.0 None 10.1016/j.ejmech.2012.03.019
None Unchecked Ratio IC50 1700.0 None 10.1039/C0MD00267D
None Unchecked Ratio IC50 1728.0 None 10.1021/acs.jnatprod.7b00587
None Unchecked Ratio IC50 1807.0 None 10.1021/acs.jmedchem.0c00131
None Unchecked Ratio IC50 1900.0 None 10.1016/j.bmc.2014.11.028
None Unchecked Ratio IC50 2000.0 None 10.1021/acsmedchemlett.8b00592
None Unchecked Ratio IC50 2437.0 None 10.1016/j.bmcl.2008.08.043
None Unchecked Ratio IC50 2505.0 None 10.1021/acs.jmedchem.0c00539
None Unchecked Ratio IC50 2505.0 None 10.1021/acs.jmedchem.8b01961
None Unchecked Ratio IC50 2564.1 None 10.1016/j.bmc.2008.09.038
None Unchecked Ratio IC50 3060.0 None 10.1021/ml400447v
None Unchecked Ratio IC50 3063.0 None 10.1021/np020070e
None Unchecked Ratio IC50 3281.0 None 10.1016/j.bmc.2009.10.013
None Unchecked Ratio IC50 4000.0 None 10.1021/acs.jnatprod.9b00721
None Unchecked Ratio IC50 4518.0 None 10.1016/j.bmcl.2015.12.080
None Unchecked Ratio IC50 6210.0 None 10.1021/np050510c
None Unchecked Ratio IC50 7512.0 None 10.1016/j.bmcl.2017.07.039
None Unchecked Ratio IC50 7512.0 None 10.1021/acs.jnatprod.7b00992
None Unchecked Ratio IC50 7592.0 None 10.1016/j.bmc.2019.115185
None Unchecked Ratio IC50 8150.0 None 10.1016/j.ejmech.2007.11.024
None Unchecked Ratio IC50 8983.0 None 10.1016/j.bmcl.2008.10.049
None Unchecked Ratio IC50 8983.0 None 10.1016/j.bmcl.2009.10.010
None Unchecked Ratio IC50 8983.0 None 10.1039/C1MD00188D
None Unchecked Ratio IC50 10610.0 None 10.1021/np9602325
None Unchecked Ratio IC50 11403.0 None 10.1021/jm500811p
None Unchecked Ratio IC50 12800.0 None 10.1016/j.ejmech.2020.112941
None Unchecked Ratio IC50 16700.0 None 10.1016/j.ejmech.2020.112969
None Unchecked Ratio IC50 21511.0 None 10.1016/j.bmcl.2015.12.080
None Unchecked Ratio IC50 23313.0 None 10.1016/j.bmc.2016.12.006
None Unchecked Ratio IC50 23313.0 None 10.1016/j.bmc.2017.02.043
None Unchecked Ratio IC50 30612.0 None 10.1016/j.bmcl.2012.07.028
None Unchecked Ratio IC50 35526.0 None 10.1016/j.bmcl.2015.09.033
None Unchecked Ratio IC50 nan None 10.1016/j.bmc.2009.01.021
None Unchecked Ratio IC50 nan None 10.1016/j.bmc.2009.10.042
None Unchecked Ratio IC50 nan None 10.1016/j.bmc.2013.12.032
None Unchecked Ratio IC50 nan None 10.1016/j.bmc.2014.11.028
None Unchecked Ratio IC50 nan None 10.1016/j.bmc.2015.02.007
None Unchecked Ratio IC50 nan None 10.1016/j.bmc.2015.05.055
None Unchecked Ratio IC50 nan None 10.1016/j.bmcl.2010.09.130
None Unchecked Ratio IC50 nan None 10.1016/j.bmcl.2011.07.112
None Unchecked Ratio IC50 nan None 10.1016/j.bmcl.2012.10.094
None Unchecked Ratio IC50 nan None 10.1016/j.bmcl.2013.12.067
None Unchecked Ratio IC50 nan None 10.1016/j.bmcl.2016.01.052
None Unchecked Ratio IC50 nan None 10.1016/j.bmcl.2016.05.024
None Unchecked Ratio IC50 nan None 10.1016/j.ejmech.2016.07.027
None Unchecked Ratio IC50 nan None 10.1016/j.ejmech.2016.12.041
None Unchecked Ratio IC50 nan None 10.1016/j.ejmech.2018.02.021
None Unchecked Ratio IC50 nan None 10.1021/acs.jmedchem.7b00140
None Unchecked Ratio IC50 nan None 10.1021/acs.jnatprod.8b00956
None Unchecked Ratio IC50 nan None 10.1021/acsmedchemlett.8b00496
None Unchecked Ratio IC50 nan None 10.1021/acsmedchemlett.9b00521
None Unchecked Ratio IC50 nan None 10.1021/jm100507q
None Unchecked Ratio IC50 nan None 10.1021/ml100120a
None Unchecked Ratio IC50 nan None 10.1021/ml300008j
None Unchecked Ratio IC50 nan None 10.1039/C2MD20136D
None Unchecked Ratio IC50 nan None 10.1039/C3MD20377H
None Unchecked Ratio IC50 nan None 10.1039/C7MD00052A
None Unchecked Resistance factor 9.57 None 10.1021/jm9901374
None Unchecked Resistance factor 10.0 None 10.1021/jm0108707
None Unchecked Resistance index 11.0 None 10.1021/jm00089a025
None Unchecked Resistance index 18.0 None 10.1021/jm00026a010
None Unchecked Selectivity index 238.0 None 10.1016/j.bmc.2006.10.036
None Unchecked Selectivity index 1700.0 None 10.1016/j.bmc.2006.10.036
None Unchecked Selectivity index 1780.0 None 10.1021/jm0201971
None Unchecked Selectivity Index 1.09 None 10.1007/s00044-011-9694-1
None Unchecked Selectivity Index 16.0 None 10.1016/j.ejmech.2019.111755
None Unchecked Selectivity Index 30.0 None 10.1016/j.bmcl.2009.10.106
None Unchecked Selectivity Index 35.0 None 10.1021/jm8007322
None Unchecked Selectivity Index 57.0 None 10.1016/j.bmc.2010.06.067
None Unchecked Selectivity Index 88.5 None 10.1016/j.ejmech.2020.112559
None Unchecked Selectivity Index 100.0 None 10.1021/acsmedchemlett.8b00222
None Unchecked Selectivity Index 113.0 None 10.1021/np050313d
None Unchecked Selectivity Index 115.0 None 10.1128/aac.01304-08
None Unchecked Selectivity Index 218.0 None 10.1016/j.ejmech.2019.111755
None Unchecked Selectivity Index 250.0 None 10.1021/np980144f
None Unchecked Selectivity Index 300.0 None 10.1016/j.bmcl.2009.10.106
None Unchecked Selectivity Index 460.0 None 10.1021/np010037c
None Unchecked Selectivity Index 480.0 None 10.1021/np50112a013
None Unchecked Selectivity Index 700.0 None 10.1016/j.bmc.2016.07.049
None Unchecked Selectivity Index 837.74 None 10.1016/j.bmc.2015.06.056
None Unchecked Selectivity Index 943.0 None 10.1128/aac.01304-08
None Unchecked Selectivity Index 2066.0 None 10.1016/j.bmcl.2016.03.027
None Unchecked Selectivity Index 2462.0 None 10.1021/jm200463z
None Unchecked Selectivity Index 3245.0 None 10.1021/np050313d
None Unchecked Selectivity Index 3628.0 None 10.1016/j.bmc.2019.01.044
None Unchecked Selectivity Index 4000.0 None 10.1021/acs.jnatprod.6b00759
None Unchecked Selectivity Index 4788.0 None 10.1016/j.bmc.2015.01.036
None Unchecked Selectivity Index 4900.0 None 10.1016/j.ejmech.2019.05.043
None Unchecked Selectivity Index 4970.0 None 10.1021/np50112a013
None Unchecked Selectivity Index 5460.0 None 10.1021/np980144f
None Unchecked Selectivity Index 5800.0 None 10.1021/np010037c
None Unchecked Selectivity Index 8983.0 None 10.1016/j.bmc.2014.09.009
None Unchecked Selectivity Index 8983.0 None 10.1016/j.ejmech.2010.12.003
None Unchecked Selectivity Index nan None 10.1016/j.bmcl.2011.01.103
None Unchecked Selectivity Index nan None 10.1016/j.ejmech.2014.04.076
None Unchecked Selectivity ratio 39.3 None 10.1016/j.bmc.2009.10.019
None Unchecked Selectivity ratio 357.9 None 10.1016/j.bmc.2009.10.019
None Unchecked VAR 53600.0 None 10.1021/jm020960r

Metabolism Information