Hyapyrroline A
AlkaPlorer ID: AK322591
Synonym: None
IUPAC Name: 2-hydroxy-1-(2-hydroxyethyl)-2,4-dimethyl-5-[(5Z,7E,9E,11E)-2,4,14-trihydroxy-9,13,15-trimethyl-17-phenylheptadeca-5,7,9,11-tetraenyl]pyrrol-3-one
Structure
SMILES: CC1=C(CC(O)CC(O)/C=C\C=C\C(C)=C\C=C\C(C)C(O)C(C)CCC2=CC=CC=C2)N(CCO)C(C)(O)C1=O
InChI: InChI=1S/C34H49NO6/c1-24(13-11-14-25(2)32(39)26(3)18-19-28-15-7-6-8-16-28)12-9-10-17-29(37)22-30(38)23-31-27(4)33(40)34(5,41)35(31)20-21-36/h6-17,25-26,29-30,32,36-39,41H,18-23H2,1-5H3/b12-9+,14-11+,17-10-,24-13+
InChIKey: FFUGEMHREAXPTP-AYKAIXJZSA-N
Reference
Hyafurones, Hyapyrrolines, and Hyapyrones: Polyketides from <i>Hyalangium minutum</i>
PubChem CID: 90681740
LOTUS: LTS0035035
NPASS: NPC477248
{NPAtlas: NPA000155
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Hyalangium minutum | Hyalangium | Archangiaceae | Myxococcales | Myxococcia | Myxococcota | None | Bacteria |
Properties Information
Molecule Weight: 567.7670000000004
TPSA？: 121.46
MolLogP？: 4.228700000000005
Number of H-Donors: 5
Number of H-Acceptors: 7
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Candida albicans | Candida albicans | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |
| Chromobacterium violaceum | Chromobacterium violaceum | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |
| Escherichia coli | Escherichia coli | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |
| Micrococcus luteus | Micrococcus luteus | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |
| Mucor hiemalis | Mucor hiemalis | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |
| Mycolicibacterium phlei | Mycolicibacterium phlei | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |
| Nocardia canis | Nocardia canis | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |
| Pseudomonas aeruginosa | Pseudomonas aeruginosa | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |
| Rhodotorula glutinis | Rhodotorula glutinis | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |
| Schizosaccharomyces pombe | Schizosaccharomyces pombe | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |
| Wickerhamomyces anomalus | Wickerhamomyces anomalus | MIC | 67.0 | ug.mL-1 | 10.1021/np500145f |