Molecule

None

AlkaPlorer ID: AK322654

Synonym: None

IUPAC Name: 5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one

Structure

SMILES: CC[C@H](NC1=NC=NC2=C1N=CN2)C1=NC2=CC=CC(F)=C2C(=O)N1C1=CC=CC=C1

InChI: InChI=1S/C22H18FN7O/c1-2-15(28-20-18-19(25-11-24-18)26-12-27-20)21-29-16-10-6-9-14(23)17(16)22(31)30(21)13-7-4-3-5-8-13/h3-12,15H,2H2,1H3,(H2,24,25,26,27,28)/t15-/m0/s1

InChIKey: IFSDAJWBUCMOAH-HNNXBMFYSA-N

Reference

PubChem CID: 11625818

CAS: 870281-82-6

NPASS: NPC478418

Source

Species	Genus	Family	Order	Class	Phylum	Kingdom	Domain
Sinularia erecta	Sinularia	Sinulariidae	Malacalcyonacea	Anthozoa	Cnidaria	Metazoa	Eukaryota
Bletilla formosana	Bletilla	Orchidaceae	Asparagales	Magnoliopsida	Streptophyta	Viridiplantae	Eukaryota

Properties Information

Molecule Weight: 415.4320000000002

TPSA？: 101.38000000000002

MolLogP？: 3.7543000000000015

Number of H-Donors: 2

Number of H-Acceptors: 7

RingCount: 5

Activities Information

Organism	Target Name	Standard Type	Standard Value	Standard Units	doi
Chlorocebus sabaeus	Vero	IC50	20000.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	26S protease regulatory subunit 6B	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	A498	GI50	1100.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	A549	IC50	330.0	nM	10.1039/C5MD00364D
Homo sapiens	Acetylcholinesterase	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Actin-related protein 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Actin-related protein 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Activin receptor type-1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Activin receptor type-1B	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Activin receptor type-2B	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Acyl-CoA dehydrogenase family member 10	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Acyl-CoA dehydrogenase family member 11	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Adaptor-associated kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Adenine phosphoribosyltransferase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Adenosine A2a receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Adenosine A3 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Adenosine kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Adenylate kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	ADP/ATP translocase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	ADP/ATP translocase 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Alpha-1a adrenergic receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2a adrenergic receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Alpha-2c adrenergic receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	AMP-activated protein kinase, alpha-1 subunit	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	AMP-activated protein kinase, gamma-1 subunit	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	AMP-activated protein kinase, gamma-2 subunit	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Androgen Receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	ATP-dependent RNA helicase DDX1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	ATP-dependent RNA helicase DDX3X	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	ATP-dependent RNA helicase DDX42	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	ATP-dependent RNA helicase DHX30	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Bel-7402	Activity	0.32	g	10.1021/acs.jmedchem.1c01520
Homo sapiens	Bel-7402	Activity	5.52	%	10.1021/acs.jmedchem.1c01520
Homo sapiens	Bel-7402	Activity	14.41	None	10.1021/acs.jmedchem.1c01520
Homo sapiens	Bel-7402	Activity	nan	None	10.1021/acs.jmedchem.1c01520
Homo sapiens	Bel-7402	IC50	66230.0	nM	10.1021/acs.jmedchem.1c01520
Homo sapiens	Bel-7402	Inhibition	9.0	%	10.1021/acs.jmedchem.1c01520
Homo sapiens	Bel-7402	Inhibition	44.56	%	10.1021/acs.jmedchem.1c01520
Homo sapiens	Bel-7402	T/C	56.1	%	10.1021/acs.jmedchem.1c01520
Homo sapiens	Beta-1 adrenergic receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Bile salt export pump	AC50	17999.9	nM	10.1038/s41467-023-40064-9
Homo sapiens	BMP-2-inducible protein kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Bone morphogenetic protein receptor type-1A	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Bone morphogenetic protein receptor type-1B	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Bone morphogenetic protein receptor type-2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Brain glycogen phosphorylase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Breakpoint cluster region protein	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Bromodomain-containing protein 4	Delta TM	-1.67	C	None
Homo sapiens	Bromodomain-containing protein 4	Delta TM	0.03447	C	None
Homo sapiens	CAKI-1	GI50	20500.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	CaM kinase II delta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	CaM kinase II gamma	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	CaM kinase IV	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	CaM-kinase kinase beta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	cAMP-dependent protein kinase alpha-catalytic subunit	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	cAMP-dependent protein kinase beta-1 catalytic subunit	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	cAMP-dependent protein kinase, gamma catalytic subunit	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	cAMP-dependent protein kinase type II-alpha regulatory subunit	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Casein kinase I alpha	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Casein kinase I delta	Delta TM	-0.1565	C	None
Homo sapiens	Casein kinase I delta	Delta TM	0.0	C	None
Homo sapiens	Casein kinase I delta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Casein kinase I epsilon	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Casein kinase I gamma 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Casein kinase I gamma 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Casein kinase II alpha (prime)	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Casein kinase I isoform gamma-3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	CCRF-CEM	GI50	22300.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	cGMP-dependent protein kinase 1 beta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Chaperone activity of bc1 complex-like, mitochondrial	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Chromodomain-helicase-DNA-binding protein 4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Citron Rho-interacting kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	c-Jun N-terminal kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	c-Jun N-terminal kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	c-Jun N-terminal kinase 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclin-dependent kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclin-dependent kinase 12	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclin-dependent kinase 13	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclin-dependent kinase 2	Delta TM	-0.6419	C	None
Homo sapiens	Cyclin-dependent kinase 2	Delta TM	0.39	C	None
Homo sapiens	Cyclin-dependent kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclin-dependent kinase 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclin-dependent kinase 4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclin-dependent kinase 5	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclin-dependent kinase 6	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclin-dependent kinase 7	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclin-dependent kinase 9	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclin-dependent kinase-like 5	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cyclooxygenase-1	AC50	4996.2	nM	10.1038/s41467-023-40064-9
Homo sapiens	Cyclooxygenase-1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Cysteine--tRNA ligase, cytoplasmic	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Cytochrome c1, heme protein, mitochondrial	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	dCTP pyrophosphatase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Delta(24)-sterol reductase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Deoxycytidine kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Discoidin domain-containing receptor 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	DNA-dependent protein kinase	IC50	6700.0	nM	10.1021/acs.jmedchem.6b00963
Homo sapiens	DNA-dependent protein kinase	IC50	6700.0	nM	10.1021/ml500354e
Homo sapiens	DnaJ homolog subfamily A member 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	DNA replication licensing factor MCM4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	DNA topoisomerase II alpha	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	DNA topoisomerase II beta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	DOHH-2	Activity	38.1	%	10.1016/j.ejmech.2022.114232
Homo sapiens	DOHH-2	Activity	57.9	%	10.1016/j.ejmech.2022.114232
Homo sapiens	DOHH-2	IC50	860.0	nM	10.1016/j.ejmech.2022.114232
Homo sapiens	Dopamine D1 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine D2 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine D3 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine transporter	AC50	9590.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dopamine transporter	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Dual specificity mitogen-activated protein kinase kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual specificity mitogen-activated protein kinase kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual specificity mitogen-activated protein kinase kinase 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual specificity mitogen-activated protein kinase kinase 4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual specificity mitogen-activated protein kinase kinase 5	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual specificity mitogen-activated protein kinase kinase 6	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual specificity protein kinase CLK2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual specificity protein kinase CLK4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual specificity testis-specific protein kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual specificity testis-specific protein kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual-specificity tyrosine-phosphorylation regulated kinase 1A	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dual specificty protein kinase CLK1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Dynamin-like 120 kDa protein, mitochondrial	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Electron transfer flavoprotein subunit beta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Elongation factor Tu, mitochondrial	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	EOL1	IC50	50000.0	nM	10.1016/j.bmcl.2023.129152
Homo sapiens	Ephrin type-A receptor 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ephrin type-A receptor 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ephrin type-A receptor 4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ephrin type-A receptor 5	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ephrin type-A receptor 7	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ephrin type-B receptor 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ephrin type-B receptor 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ephrin type-B receptor 4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ephrin type-B receptor 6	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Epidermal growth factor receptor erbB1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Epithelial discoidin domain-containing receptor 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Estrogen receptor alpha	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Eukaryotic translation initiation factor 2-alpha kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Eukaryotic translation initiation factor 5B	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Exosome RNA helicase MTR4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ferrochelatase, mitochondrial	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Fibroblast	Control DMSO Apoptotic Cells (%)	52.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Apoptotic Cells (%)	55.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Apoptotic Cells (%)	65.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Apoptotic Cells (%)	69.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Apoptotic Cells (%)	80.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	55.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	58.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Fragmented Nuclei %	59.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Growth Rate	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Growth Rate	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Growth Rate	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Growth Rate	231110.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	34.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	53.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	59.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Healthy Nuclei (%)	61.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Membrane Permeable-Phenotype Cells (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitochondria Different-Phenotype Cells (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	34.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	44.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Mitotic Cells (%)	47.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Pyknosed Nuclei (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	80.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	84.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	99.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	211.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	230.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Total Cells	242.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Control DMSO Tubulin Phenotype Different Cells (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Growth Rate	-0.73	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	-0.51	None	10.6019/CHEMBL5303304
Homo sapiens	Fibroblast	Growth Rate	-0.13	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	-0.05	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	-0.04	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	0.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Growth Rate	0.15	None	10.6019/CHEMBL5303304
Homo sapiens	Fibroblast	Growth Rate	0.25	None	10.6019/CHEMBL5303304
Homo sapiens	Fibroblast	Growth Rate	0.36	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	0.48	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	0.49	None	10.6019/CHEMBL5303304
Homo sapiens	Fibroblast	Growth Rate	0.59	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	0.75	None	10.6019/CHEMBL5058564
Homo sapiens	Fibroblast	Growth Rate	0.92	None	10.6019/CHEMBL5303304
Homo sapiens	Fibroblast	Growth Rate	0.95	None	10.6019/CHEMBL5303304
Homo sapiens	Fibroblast	Growth Rate	1.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	50.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	58.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	59.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	66.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	73.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	91.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Apoptotic (%)	95.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	47.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	56.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	58.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	67.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Fragmented Nuclei (%)	70.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	34.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	43.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	47.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	51.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	54.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	56.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Healthy Nuclei (%)	59.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	34.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	35.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Hoechst High Intensity Objects (%)	43.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Membrane Permeable-Phenotype (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	35.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitochondria Different-Phenotype (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	41.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	50.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	60.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Mitotic Cells (%)	100.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	56.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	65.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	69.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	77.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	87.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	88.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	89.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Normal (%)	90.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Pyknosed Nuclei (%)	17.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	21.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Population Tubulin-Different-Phenotype (%)	53.0	%	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	60.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	63.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	67.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	73.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	77.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	110.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	156.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	184.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	199.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	211.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	221.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast	Total Cell Count	222.0	None	10.6019/CHEMBL4689842
Homo sapiens	Fibroblast growth factor receptor 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Fibroblast growth factor receptor 3	Delta TM	0.03	C	None
Homo sapiens	Fibroblast growth factor receptor 3	Delta TM	0.05233	C	None
Homo sapiens	Focal adhesion kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	General transcription and DNA repair factor IIH helicase subunit XPD	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Glycine--tRNA ligase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Glycogen synthase kinase-3 alpha	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Glycogen synthase kinase-3 beta	Delta TM	-0.32	C	None
Homo sapiens	Glycogen synthase kinase-3 beta	Delta TM	-0.008089	C	None
Homo sapiens	Glycogen synthase kinase-3 beta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	G-protein coupled receptor kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	G protein-coupled receptor kinase 6	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	GTP-binding nuclear protein Ran	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Guanine nucleotide-binding protein G(i) subunit alpha-2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	HCC 2998	GI50	38500.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	HCT-116	IC50	2960.0	nM	10.1016/j.bmc.2022.117028
Homo sapiens	HCT-116	IC50	10000.0	nM	10.1016/j.bmc.2019.07.051
Homo sapiens	HEK293	IC50	20000.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Apoptotic Cells (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Fragmented Nuclei %	23.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Growth Rate	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Growth Rate	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	49.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	69.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	73.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	77.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	79.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Healthy Nuclei (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Membrane Permeable-Phenotype Cells (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitochondria Different-Phenotype Cells (%)	32.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	81.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	83.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	84.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Mitotic Cells (%)	91.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Pyknosed Nuclei (%)	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	691.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	838.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	865.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	1080.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	1765.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Total Cells	3025.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Control DMSO Tubulin Phenotype Different Cells (%)	45.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Growth Rate	-0.34	None	10.6019/CHEMBL5303304
Homo sapiens	HEK-293T	Growth Rate	0.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Growth Rate	0.12	None	10.6019/CHEMBL5303304
Homo sapiens	HEK-293T	Growth Rate	0.2	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.29	None	10.6019/CHEMBL5303304
Homo sapiens	HEK-293T	Growth Rate	0.31	None	10.6019/CHEMBL5303304
Homo sapiens	HEK-293T	Growth Rate	0.36	None	10.6019/CHEMBL5303304
Homo sapiens	HEK-293T	Growth Rate	0.38	None	10.6019/CHEMBL5303304
Homo sapiens	HEK-293T	Growth Rate	0.52	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.56	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.57	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.62	None	10.6019/CHEMBL5303304
Homo sapiens	HEK-293T	Growth Rate	0.64	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.68	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.7	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Growth Rate	0.76	None	10.6019/CHEMBL5058564
Homo sapiens	HEK-293T	Population Apoptotic (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	17.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Apoptotic (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	17.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Fragmented Nuclei (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	43.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	44.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	46.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	60.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	67.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	68.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	77.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	78.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Healthy Nuclei (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Hoechst High Intensity Objects (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Membrane Permeable-Phenotype (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	22.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitochondria Different-Phenotype (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	77.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	81.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	82.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	84.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	87.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	89.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	91.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Mitotic Cells (%)	96.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	80.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	81.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	89.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	91.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	94.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	96.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Normal (%)	97.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	17.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	23.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	34.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Pyknosed Nuclei (%)	35.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	48.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	64.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Population Tubulin-Different-Phenotype (%)	68.0	%	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	500.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	587.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	588.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	613.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	888.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	911.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	995.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1058.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1315.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	1603.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	2065.0	None	10.6019/CHEMBL4689842
Homo sapiens	HEK-293T	Total Cell Count	2772.0	None	10.6019/CHEMBL4689842
Homo sapiens	HeLa	IC50	150.0	nM	10.1039/C5MD00364D
Homo sapiens	Heme oxygenase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Hep 3B2	IC50	77550.0	nM	10.1021/acs.jmedchem.1c01520
Homo sapiens	Hep 3B2	Inhibition	21.0	%	10.1021/acs.jmedchem.1c01520
Homo sapiens	Hepatocyte growth factor receptor	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	HepG2	IC50	920.0	nM	10.1039/C5MD00364D
Homo sapiens	HepG2	IC50	89500.0	nM	10.1021/acs.jmedchem.1c01520
Homo sapiens	HepG2	Inhibition	20.0	%	10.1021/acs.jmedchem.1c01520
Homo sapiens	HERG	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Histamine H1 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Histamine H3 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Histone deacetylase 1	IC50	nan	None	10.1016/j.bmc.2022.117028
Homo sapiens	Histone deacetylase 6	IC50	nan	None	10.1016/j.bmc.2022.117028
Homo sapiens	Histone deacetylase 6	Inhibition	-5.22	%	10.6019/CHEMBL4808148
Homo sapiens	Histone deacetylase 6	Inhibition	-3.14	%	10.6019/CHEMBL4808148
Homo sapiens	HL-60	IC50	480.0	nM	10.1016/j.bmcl.2023.129152
Homo sapiens	Homo sapiens	Activity	56.0	%	10.1021/jm300847w
Homo sapiens	Homo sapiens	MTD	200.0	mg	10.1021/jm300847w
Homo sapiens	Homo sapiens	MTD	400.0	mg	10.1021/jm300847w
Homo sapiens	HOP-62	GI50	100000.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	HOP-92	GI50	14100.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	Hs-578T	GI50	6000.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	HT	IC50	10000.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	HUVEC	IC50	38220.0	nM	10.1016/j.bmc.2022.117028
Homo sapiens	IGROV-1	GI50	4800.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	Inhibitor of nuclear factor kappa B kinase epsilon subunit	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Inosine-5'-monophosphate dehydrogenase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Insulin-like growth factor I receptor	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Insulin receptor	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Interleukin-1 receptor-associated kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Interleukin-1 receptor-associated kinase 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Interleukin-1 receptor-associated kinase 4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	JeKo-1	IC50	120.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	KARPAS-422	GI50	680.0	nM	10.1021/acsmedchemlett.7b00222
Homo sapiens	KARPAS-422	IC50	8100.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	KG-1	IC50	15200.0	nM	10.1016/j.bmcl.2023.129152
Homo sapiens	KM12	GI50	1200.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	KM12	IC50	960.0	nM	10.1016/j.bmc.2022.117028
Homo sapiens	L02	IC50	20000.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	LIM domain kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	LIM domain kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Liver glycogen phosphorylase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Long-chain-fatty-acid--CoA ligase 5	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	LOX IMVI	GI50	33500.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	M14	GI50	37800.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	Macrophage-stimulating protein receptor	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	MAP kinase-activated protein kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	MAP kinase-activated protein kinase 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	MAP kinase-activated protein kinase 5	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	MAP kinase ERK1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	MAP kinase ERK2	Delta TM	-0.09	C	None
Homo sapiens	MAP kinase ERK2	Delta TM	-0.04486	C	None
Homo sapiens	MAP kinase ERK2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	MAP kinase p38 alpha	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	MAP kinase p38 beta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	MAP/microtubule affinity-regulating kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	MAP/microtubule affinity-regulating kinase 4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Maternal embryonic leucine zipper kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	MCF7	GI50	nan	None	10.1021/acsmedchemlett.7b00222
Homo sapiens	MCF7	IC50	780.0	nM	10.1039/C5MD00364D
Homo sapiens	MCF7	IC50	10000.0	nM	10.1016/j.bmc.2019.07.051
Homo sapiens	MDA-MB-231	GI50	42300.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	Melanocortin receptor 3	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Membrane-associated progesterone receptor component 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Midasin	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Misshapen-like kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase 15	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase 7	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase 11	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase 4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase 5	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase 6	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase kinase 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase kinase 4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitogen-activated protein kinase kinase kinase kinase 5	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mitotic checkpoint serine/threonine-protein kinase BUB1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mixed lineage kinase 7	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	MOLM-13	GI50	1700.0	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	MOLM-14	Activity	nan	None	10.1016/j.ejmech.2018.07.036
Homo sapiens	MOLM-14	GI50	6400.0	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	MOLM-14	TGI	nan	None	10.1016/j.ejmech.2018.07.036
Homo sapiens	MOLT-4	Activity	2.34	%	10.1016/j.bmc.2021.116312
Homo sapiens	MOLT-4	Activity	19.2	%	10.1016/j.bmc.2021.116312
Homo sapiens	MOLT-4	Activity	22.0	%	10.1016/j.bmc.2021.116312
Homo sapiens	MOLT-4	Activity	56.5	%	10.1016/j.bmc.2021.116312
Homo sapiens	MOLT-4	Activity	74.57	%	10.1016/j.bmc.2021.116312
Homo sapiens	MOLT-4	IC50	10000.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	MOLT-4	Inhibition	nan	%	10.1016/j.bmc.2021.116312
Homo sapiens	Monoamine oxidase A	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	MRC5	IC50	100000.0	nM	10.1016/j.bmc.2021.116312
Homo sapiens	MRC5	Inhibition	18.41	%	10.1016/j.bmc.2021.116312
Homo sapiens	Multifunctional protein ADE2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Mu opioid receptor	AC50	14610.3	nM	10.1038/s41467-023-40064-9
Homo sapiens	Muscarinic acetylcholine receptor M1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Muscarinic acetylcholine receptor M2	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	MV4-11	GI50	10000.0	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	MV4-11	IC50	4300.0	nM	10.1016/j.bmcl.2023.129152
Homo sapiens	MV4-11	Inhibition	nan	%	10.1021/acs.jmedchem.0c00193
Homo sapiens	Myosin light chain kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Myosin light chain kinase, smooth muscle	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	NALM-6	GI50	10000.0	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	NAMALVA	IC50	10000.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	NCI-H460	GI50	nan	None	10.1021/acsmedchemlett.7b00222
Homo sapiens	Nerve growth factor receptor Trk-A	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Neuronal acetylcholine receptor protein alpha-4 subunit	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Neutrophil	IC50	70.0	nM	10.1021/acs.jnatprod.5b01142
Homo sapiens	Neutrophil	IC50	300.0	nM	10.1021/acs.jnatprod.5b01142
Homo sapiens	Neutrophil	Inhibition	100.0	%	10.1021/acs.jnatprod.5b01142
Homo sapiens	Neutrophil	Inhibition	103.0	%	10.1021/acs.jnatprod.5b01142
Homo sapiens	Non-receptor tyrosine-protein kinase TNK1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Norepinephrine transporter	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	NUAK family SNF1-like kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Nucleolar GTP-binding protein 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	OCI-Ly10	Activity	0.48	g	10.1021/acs.jmedchem.0c01264
Homo sapiens	OCI-Ly10	Activity	828.42	mm3	10.1021/acs.jmedchem.0c01264
Homo sapiens	OCI-Ly10	IC50	31.9	nM	10.1021/acs.jmedchem.0c01264
Homo sapiens	OCI-Ly10	IC50	10000.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	OCI-Ly10	TGI	47.33	%	10.1021/acs.jmedchem.0c01264
Homo sapiens	OCI-Ly3	IC50	5200.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	OVCAR-3	GI50	17700.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	PAS domain-containing serine/threonine-protein kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Peregrin	Delta TM	-1.86	C	None
Homo sapiens	Peregrin	Delta TM	0.4331	C	None
Homo sapiens	Peroxisomal acyl-coenzyme A oxidase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Peroxisomal acyl-coenzyme A oxidase 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	PF-382	GI50	10000.0	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	Pfeiffer	GI50	740.0	nM	10.1021/acsmedchemlett.7b00222
Homo sapiens	Pfeiffer	IC50	6800.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	Phenylalanine--tRNA ligase beta subunit	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Phosphatidylethanolamine-binding protein 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Phosphatidylinositol 3-kinase catalytic subunit type 3	IC50	980.0	nM	10.1021/acs.jmedchem.8b01298
Homo sapiens	Phosphatidylinositol 3-kinase catalytic subunit type 3	IC50	4417.0	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	Phosphatidylinositol 3-kinase catalytic subunit type 3	IC50	978000.0	nM	10.1021/acs.jmedchem.6b00963
Homo sapiens	Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	IC50	579.0	nM	10.1039/C5MD00364D
Homo sapiens	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide	IC50	1000.0	nM	10.1021/acs.jmedchem.6b00963
Homo sapiens	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide	IC50	1000.0	nM	10.1021/ml500354e
Homo sapiens	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide	IC50	10000.0	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha	IC50	10000.0	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha	IC50	nan	None	10.1021/ml500354e
Homo sapiens	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma	IC50	nan	None	10.1021/ml500354e
Homo sapiens	Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Phosphodiesterase 3A	AC50	15153.7	nM	10.1038/s41467-023-40064-9
Homo sapiens	Phosphodiesterase 3A	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Phosphodiesterase 4A	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Phosphodiesterase 4D	AC50	17999.9	nM	10.1038/s41467-023-40064-9
Homo sapiens	Phosphofructokinase platelet type	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Phosphorylase kinase gamma subunit 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	PI3-kinase p110-alpha/p85-alpha	IC50	409.0	nM	10.1016/j.bmc.2021.116312
Homo sapiens	PI3-kinase p110-alpha/p85-alpha	IC50	800.0	nM	10.1016/j.ejmech.2018.11.072
Homo sapiens	PI3-kinase p110-alpha/p85-alpha	IC50	825.0	nM	10.1039/C5MD00364D
Homo sapiens	PI3-kinase p110-alpha/p85-alpha	IC50	2000.0	nM	10.1016/j.ejmech.2018.09.033
Homo sapiens	PI3-kinase p110-alpha/p85-alpha	IC50	2164.0	nM	10.1016/j.ejmech.2019.03.005
Homo sapiens	PI3-kinase p110-alpha/p85-alpha	IC50	7500.0	nM	10.1021/acs.jmedchem.6b01821
Homo sapiens	PI3-kinase p110-alpha/p85-alpha	IC50	8600.0	nM	10.1021/acs.jmedchem.9b00640
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	177.2	nM	10.1016/j.bmc.2019.07.051
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	306.4	nM	10.1016/j.bmc.2018.03.002
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	332.0	nM	10.1016/j.bmcl.2023.129152
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	391.3	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	467.0	nM	10.1016/j.bmc.2022.117028
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	500.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	583.0	nM	10.1016/j.bmc.2019.05.043
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	737.0	nM	10.1016/j.ejmech.2018.03.068
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	800.0	nM	10.1016/j.bmcl.2017.01.077
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	800.0	nM	10.1021/acs.jmedchem.7b00618
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	820.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	820.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	820.0	nM	10.1021/acs.jmedchem.1c00986
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	820.0	nM	10.1021/acs.jmedchem.1c01520
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	820.0	nM	10.1021/jm301522m
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	820.0	nM	10.1039/C2MD20044A
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	822.0	nM	10.1039/C8MD00556G
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	1650.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	8695.5	nM	10.1021/acs.jmedchem.1c00004
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	9700.0	nM	10.1016/j.bmcl.2015.01.001
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	10000.0	nM	10.1021/acs.jmedchem.9b01499
Homo sapiens	PI3-kinase p110-alpha subunit	IC50	nan	None	10.1021/acs.jmedchem.1c00004
Homo sapiens	PI3-kinase p110-beta subunit	IC50	120.1	nM	10.1016/j.bmc.2018.03.002
Homo sapiens	PI3-kinase p110-beta subunit	IC50	129.0	nM	10.1016/j.ejmech.2018.03.068
Homo sapiens	PI3-kinase p110-beta subunit	IC50	134.0	nM	10.1016/j.bmc.2019.05.043
Homo sapiens	PI3-kinase p110-beta subunit	IC50	139.1	nM	10.1016/j.bmc.2019.07.051
Homo sapiens	PI3-kinase p110-beta subunit	IC50	154.0	nM	10.1016/j.ejmech.2019.03.005
Homo sapiens	PI3-kinase p110-beta subunit	IC50	198.0	nM	10.1016/j.bmcl.2023.129152
Homo sapiens	PI3-kinase p110-beta subunit	IC50	281.0	nM	10.1039/C8MD00556G
Homo sapiens	PI3-kinase p110-beta subunit	IC50	380.0	nM	10.1016/j.bmcl.2017.01.077
Homo sapiens	PI3-kinase p110-beta subunit	IC50	380.0	nM	10.1021/acs.jmedchem.7b00618
Homo sapiens	PI3-kinase p110-beta subunit	IC50	500.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	PI3-kinase p110-beta subunit	IC50	562.0	nM	10.1021/jm301522m
Homo sapiens	PI3-kinase p110-beta subunit	IC50	564.0	nM	10.1021/acs.jmedchem.1c00986
Homo sapiens	PI3-kinase p110-beta subunit	IC50	565.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	PI3-kinase p110-beta subunit	IC50	565.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	PI3-kinase p110-beta subunit	IC50	565.0	nM	10.1021/acs.jmedchem.1c01520
Homo sapiens	PI3-kinase p110-beta subunit	IC50	565.0	nM	10.1039/C2MD20044A
Homo sapiens	PI3-kinase p110-beta subunit	IC50	571.0	nM	10.1016/j.bmcl.2019.04.007
Homo sapiens	PI3-kinase p110-beta subunit	IC50	613.0	nM	10.1016/j.bmc.2021.116312
Homo sapiens	PI3-kinase p110-beta subunit	IC50	669.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	PI3-kinase p110-beta subunit	IC50	845.5	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	PI3-kinase p110-beta subunit	IC50	1400.0	nM	10.1016/j.bmcl.2015.01.001
Homo sapiens	PI3-kinase p110-beta subunit	IC50	1995.26	nM	10.1021/acs.jmedchem.9b01499
Homo sapiens	PI3-kinase p110-beta subunit	IC50	2473.5	nM	10.1021/acs.jmedchem.1c00004
Homo sapiens	PI3-kinase p110-beta subunit	IC50	4000.0	nM	10.1021/acs.jmedchem.9b00640
Homo sapiens	PI3-kinase p110-beta subunit	IC50	nan	None	10.1021/acs.jmedchem.1c00004
Homo sapiens	PI3-kinase p110-delta/p85-alpha	IC50	1.08	nM	10.1016/j.bmc.2021.116312
Homo sapiens	PI3-kinase p110-delta/p85-alpha	IC50	1.8	nM	10.1016/j.ejmech.2019.03.005
Homo sapiens	PI3-kinase p110-delta/p85-alpha	IC50	2.0	nM	10.1021/acs.jmedchem.8b02014
Homo sapiens	PI3-kinase p110-delta/p85-alpha	IC50	2.7	nM	10.1016/j.bmcl.2017.03.020
Homo sapiens	PI3-kinase p110-delta/p85-alpha	IC50	3.4	nM	10.1016/j.ejmech.2020.112143
Homo sapiens	PI3-kinase p110-delta/p85-alpha	IC50	17.0	nM	10.1016/j.ejmech.2018.09.033
Homo sapiens	PI3-kinase p110-delta/p85-alpha	IC50	18.0	nM	10.1021/acs.jmedchem.6b01821
Homo sapiens	PI3-kinase p110-delta/p85-alpha	IC50	19.0	nM	10.1021/acs.jmedchem.9b00640
Homo sapiens	PI3-kinase p110-delta/p85-alpha	IC50	25.0	nM	10.1021/acs.jmedchem.6b00963
Homo sapiens	PI3-kinase p110-delta/p85-alpha	Inhibition	50.0	%	10.1021/acs.jmedchem.8b02014
Homo sapiens	PI3-kinase p110-delta/p85-alpha	Inhibition	96.0	%	10.1016/j.bmcl.2017.03.020
Homo sapiens	PI3-kinase p110-delta subunit	Activity	nan	None	10.1021/acs.jmedchem.0c00193
Homo sapiens	PI3-kinase p110-delta subunit	EC50	8.0	nM	10.1016/j.ejmech.2021.113218
Homo sapiens	PI3-kinase p110-delta subunit	IC50	1.0	nM	10.1016/j.bmcl.2023.129152
Homo sapiens	PI3-kinase p110-delta subunit	IC50	1.2	nM	10.1016/j.bmc.2019.07.051
Homo sapiens	PI3-kinase p110-delta subunit	IC50	1.6	nM	10.1016/j.ejmech.2018.03.068
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.0	nM	10.1016/j.bmcl.2017.01.077
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.0	nM	10.1016/j.ejmech.2018.11.072
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.0	nM	10.1016/j.ejmech.2021.113661
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.0	nM	10.1021/acs.jmedchem.7b00618
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.0	nM	10.1021/acsmedchemlett.6b00209
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.1	nM	10.1016/j.bmcl.2019.04.007
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.5	nM	10.1016/j.bmc.2018.03.002
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.5	nM	10.1016/j.bmcl.2018.02.032
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.5	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.5	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.5	nM	10.1016/j.ejmech.2021.113218
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.5	nM	10.1021/acs.jmedchem.1c00986
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.5	nM	10.1021/acs.jmedchem.8b01298
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.5	nM	10.1021/jm301522m
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.5	nM	10.1039/C2MD20044A
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.5	nM	None
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.7	nM	10.1016/j.bmc.2018.03.002
Homo sapiens	PI3-kinase p110-delta subunit	IC50	2.7	nM	10.1016/j.bmcl.2015.01.001
Homo sapiens	PI3-kinase p110-delta subunit	IC50	3.0	nM	10.1039/C5MD00364D
Homo sapiens	PI3-kinase p110-delta subunit	IC50	3.1	nM	10.1016/j.bmc.2019.05.043
Homo sapiens	PI3-kinase p110-delta subunit	IC50	3.2	nM	10.1039/C8MD00556G
Homo sapiens	PI3-kinase p110-delta subunit	IC50	4.0	nM	10.1021/acs.jmedchem.8b02014
Homo sapiens	PI3-kinase p110-delta subunit	IC50	4.3	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	PI3-kinase p110-delta subunit	IC50	4.7	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	PI3-kinase p110-delta subunit	IC50	5.9	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	PI3-kinase p110-delta subunit	IC50	6.0	nM	10.1021/acs.jmedchem.0c01544
Homo sapiens	PI3-kinase p110-delta subunit	IC50	6.1	nM	10.1021/jm300847w
Homo sapiens	PI3-kinase p110-delta subunit	IC50	7.0	nM	10.1016/j.bmc.2022.117028
Homo sapiens	PI3-kinase p110-delta subunit	IC50	9.0	nM	10.1016/j.ejmech.2016.02.018
Homo sapiens	PI3-kinase p110-delta subunit	IC50	9.0	nM	10.1021/jm300847w
Homo sapiens	PI3-kinase p110-delta subunit	IC50	9.0	nM	None
Homo sapiens	PI3-kinase p110-delta subunit	IC50	10.0	nM	10.1021/acs.jmedchem.9b01499
Homo sapiens	PI3-kinase p110-delta subunit	IC50	19.0	nM	10.1021/acs.jmedchem.8b01732
Homo sapiens	PI3-kinase p110-delta subunit	IC50	24.0	nM	10.1016/j.bmcl.2015.01.001
Homo sapiens	PI3-kinase p110-delta subunit	IC50	25.0	nM	10.1021/ml500354e
Homo sapiens	PI3-kinase p110-delta subunit	IC50	31.0	nM	10.1021/acs.jmedchem.1c00004
Homo sapiens	PI3-kinase p110-delta subunit	IC50	48.93	nM	10.1021/acs.jmedchem.1c00004
Homo sapiens	PI3-kinase p110-delta subunit	IC50	831.0	nM	10.1016/j.bmcl.2019.04.007
Homo sapiens	PI3-kinase p110-delta subunit	IC50	nan	None	10.1021/acs.jmedchem.1c00004
Homo sapiens	PI3-kinase p110-delta subunit	Inhibition	91.91	%	10.1016/j.ejmech.2018.03.068
Homo sapiens	PI3-kinase p110-delta subunit	Inhibition	96.0	%	10.1016/j.bmc.2018.03.002
Homo sapiens	PI3-kinase p110-delta subunit	Inhibition	96.0	%	10.1016/j.bmcl.2019.04.007
Homo sapiens	PI3-kinase p110-delta subunit	Inhibition	nan	%	10.1016/j.bmc.2021.116312
Homo sapiens	PI3-kinase p110-delta subunit	Inhibition	nan	%	10.1021/acsmedchemlett.6b00209
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	27.4	nM	10.1016/j.bmc.2021.116312
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	50.5	nM	10.1016/j.bmc.2022.117028
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	60.0	nM	10.1016/j.bmcl.2023.129152
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	60.0	nM	10.1039/C8MD00556G
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	63.0	nM	10.1016/j.bmcl.2017.01.077
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	63.0	nM	10.1016/j.ejmech.2018.11.072
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	63.0	nM	10.1016/j.ejmech.2019.03.005
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	63.0	nM	10.1021/acs.jmedchem.7b00618
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	64.0	nM	10.1021/acsmedchemlett.6b00209
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	67.0	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	89.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	89.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	89.0	nM	10.1021/acs.jmedchem.1c00986
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	89.0	nM	10.1021/acs.jmedchem.1c01520
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	89.0	nM	10.1021/acs.jmedchem.8b01298
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	89.0	nM	10.1021/jm301522m
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	89.0	nM	10.1039/C2MD20044A
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	92.0	nM	10.1016/j.bmcl.2019.04.007
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	92.0	nM	10.1039/C5MD00364D
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	104.0	nM	10.1021/acs.jmedchem.8b02014
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	139.0	nM	10.1016/j.ejmech.2018.03.068
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	139.4	nM	10.1016/j.bmc.2018.03.002
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	145.3	nM	10.1016/j.bmc.2019.07.051
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	199.53	nM	10.1021/acs.jmedchem.9b01499
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	241.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	245.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	250.0	nM	10.1016/j.ejmech.2018.09.033
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	381.0	nM	10.1016/j.bmc.2019.05.043
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	580.0	nM	10.1016/j.bmcl.2015.01.001
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	2100.0	nM	10.1021/acs.jmedchem.6b01821
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	2100.0	nM	10.1021/acs.jmedchem.9b00640
Homo sapiens	PI3-kinase p110-gamma subunit	IC50	nan	None	10.1021/acs.jmedchem.1c00004
Homo sapiens	PI3-kinase p110-gamma subunit	Inhibition	50.0	%	10.1021/acs.jmedchem.8b02014
Homo sapiens	PI3K p110 beta/p85 alpha	IC50	293.0	nM	10.1021/acs.jmedchem.8b02014
Homo sapiens	PI3K p110 beta/p85 alpha	IC50	600.0	nM	10.1016/j.ejmech.2018.09.033
Homo sapiens	PI3K p110 beta/p85 alpha	IC50	3700.0	nM	10.1021/acs.jmedchem.6b01821
Homo sapiens	PI3K p110 beta/p85 alpha	IC50	3807.0	nM	10.1016/j.ejmech.2018.11.072
Homo sapiens	PI3K p110 beta/p85 alpha	Inhibition	50.0	%	10.1021/acs.jmedchem.8b02014
Homo sapiens	PI4-kinase alpha subunit	IC50	10000.0	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	PI4-kinase beta subunit	IC50	10000.0	nM	10.1016/j.ejmech.2018.07.036
Homo sapiens	Platelet-derived growth factor receptor beta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Pregnane X receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Pregnane X receptor	Activity	3.7	%	10.1016/j.bmcl.2015.01.001
Homo sapiens	Probable ATP-dependent RNA helicase DDX6	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Progesterone receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Protein kinase C alpha	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Protein kinase C beta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Protein kinase C delta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Protein kinase C iota	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Protein kinase C nu	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Protein kinase C theta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Protein kinase N1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Protein kinase N2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Protein tyrosine kinase 2 beta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Putative heat shock protein HSP 90-beta 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Pyridoxal kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Quinone reductase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Rab-like protein 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Raji	IC50	9.95	nM	10.1016/j.bmcl.2017.03.020
Homo sapiens	Raji	IC50	9950.0	nM	10.1016/j.bmc.2018.03.002
Homo sapiens	Raji	IC50	10000.0	nM	10.1016/j.bmc.2019.07.051
Homo sapiens	Ramos	IC50	10.0	nM	10.1016/j.bmcl.2017.03.020
Homo sapiens	Ramos	IC50	10000.0	nM	10.1016/j.bmc.2018.03.002
Homo sapiens	Ramos	IC50	10000.0	nM	10.1016/j.bmc.2019.07.051
Homo sapiens	Ras-related protein Rab-10	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ras-related protein Rab-27A	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ras-related protein Rab-6A	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Receptor-interacting serine/threonine-protein kinase 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Rho-associated protein kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Rho-associated protein kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ribosomal protein S6 kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ribosomal protein S6 kinase alpha 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ribosomal protein S6 kinase alpha 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ribosomal protein S6 kinase alpha 4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ribosomal protein S6 kinase alpha 5	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Ribosomal protein S6 kinase alpha 6	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	RNA cytidine acetyltransferase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	RPMI-8226	IC50	5490.0	nM	10.1016/j.bmc.2018.03.002
Homo sapiens	RXF 393	GI50	1400.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	S-adenosylmethionine synthase isoform type-2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Septin-9	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine-protein kinase ATR	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase 10	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase 11	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase 16	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase 24	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase 38	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase 38-like	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase AKT	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase AKT2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase AKT3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase A-Raf	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase Aurora-A	Delta TM	-0.27	C	None
Homo sapiens	Serine/threonine-protein kinase Aurora-A	Delta TM	0.281	C	None
Homo sapiens	Serine/threonine-protein kinase Aurora-A	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase Aurora-B	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase B-raf	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase Chk1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase c-TAK1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase D2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase/endoribonuclease IRE1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase/endoribonuclease IRE2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase GAK	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase ICK	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase ILK-1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase LATS1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase MRCK-A	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase MRCK beta	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase MRCK gamma	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase MST1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase MST2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase MST4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase mTOR	IC50	1000.0	nM	10.1016/j.bmcl.2019.04.007
Homo sapiens	Serine/threonine-protein kinase mTOR	IC50	10000.0	nM	10.1039/C2MD20044A
Homo sapiens	Serine/threonine-protein kinase N3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase Nek1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase NEK2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase Nek3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase NEK9	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine protein kinase NLK	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase PAK 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase PAK 4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase PAK6	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase PCTAIRE-1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase PCTAIRE-2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase PIM1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase PLK1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase PLK4	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase RIPK2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase SIK2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase SIK3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase TAO1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase TAO2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase TAO3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase TBK1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase ULK1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase ULK3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serine/threonine-protein kinase WEE1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Serotonin 1a (5-HT1a) receptor	AC50	4604.6	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 2a (5-HT2a) receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin 2b (5-HT2b) receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Serotonin transporter	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Signal recognition particle receptor subunit alpha	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	SNB-75	GI50	1200.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	STE20-related kinase adapter protein alpha	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Structural maintenance of chromosomes protein 1A	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Structural maintenance of chromosomes protein 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	SUD4	IC50	1600.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	SU-DHL-1	IC50	10000.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	SU-DHL10	Activity	1.7	%	10.1016/j.bmc.2021.116312
Homo sapiens	SU-DHL10	Activity	12.2	%	10.1016/j.bmc.2021.116312
Homo sapiens	SU-DHL10	Activity	30.4	%	10.1016/j.bmc.2021.116312
Homo sapiens	SU-DHL10	Activity	55.7	%	10.1016/j.bmc.2021.116312
Homo sapiens	SU-DHL10	IC50	10000.0	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	SU-DHL-5	Activity	41.34	%	10.1016/j.bmc.2021.116312
Homo sapiens	SU-DHL-6	Activity	1.25	g	10.1021/acs.jmedchem.0c01264
Homo sapiens	SU-DHL-6	Activity	1276.78	mm3	10.1021/acs.jmedchem.0c01264
Homo sapiens	SU-DHL-6	GI50	20.0	nM	10.1039/C8MD00556G
Homo sapiens	SU-DHL-6	GI50	34.0	nM	10.1016/j.ejmech.2020.112143
Homo sapiens	SU-DHL-6	GI50	42.0	nM	10.1016/j.ejmech.2018.03.068
Homo sapiens	SU-DHL-6	GI50	124.0	nM	10.1016/j.ejmech.2019.03.005
Homo sapiens	SU-DHL-6	IC50	22.5	nM	10.1021/acs.jmedchem.0c01264
Homo sapiens	SU-DHL-6	IC50	33.0	nM	10.1016/j.bmc.2019.07.051
Homo sapiens	SU-DHL-6	IC50	53.0	nM	10.1016/j.bmc.2022.117028
Homo sapiens	SU-DHL-6	IC50	117.6	nM	10.1016/j.ejmech.2016.11.014
Homo sapiens	SU-DHL-6	IC50	120.0	nM	10.1016/j.bmcl.2020.127479
Homo sapiens	SU-DHL-6	IC50	650.0	nM	10.1016/j.bmc.2018.03.002
Homo sapiens	SU-DHL-6	TGI	38.52	%	10.1021/acs.jmedchem.0c01264
Homo sapiens	T47D	GI50	5200.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	T47D	GI50	nan	None	10.1021/acsmedchemlett.7b00222
Homo sapiens	T47D	IC50	510.0	nM	10.1016/j.bmc.2022.117028
Homo sapiens	TGF-beta receptor type I	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	TGF-beta receptor type II	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Thrombin	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Thromboxane A2 receptor	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Thyroid hormone receptor-associated protein 3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	TMD8	Activity	1.07	g	10.1021/acs.jmedchem.0c01264
Homo sapiens	TMD8	Activity	1312.58	mm3	10.1021/acs.jmedchem.0c01264
Homo sapiens	TMD8	IC50	7.3	nM	10.1021/acs.jmedchem.0c01264
Homo sapiens	TMD8	IC50	795.0	nM	10.1016/j.bmcl.2019.04.007
Homo sapiens	TMD8	TGI	29.28	%	10.1021/acs.jmedchem.0c01264
Homo sapiens	TP53-regulating kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	TRAF2- and NCK-interacting kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Transcription intermediary factor 1-alpha	Delta TM	-0.98	C	None
Homo sapiens	Transcription intermediary factor 1-alpha	Delta TM	-0.2391	C	None
Homo sapiens	Tyrosine- and threonine-specific cdc2-inhibitory kinase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine kinase non-receptor protein 2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase ABL	Delta TM	-0.1913	C	None
Homo sapiens	Tyrosine-protein kinase ABL	Delta TM	0.82	C	None
Homo sapiens	Tyrosine-protein kinase ABL	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase ABL2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase BRK	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase BTK	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase CSK	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase FER	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase FES	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase FGR	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase FRK	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase FYN	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase HCK	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase JAK1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase LCK	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase Lyn	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase receptor FLT3	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase receptor RET	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase SRC	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase SYK	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase TEC	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase TYK2	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosine-protein kinase YES	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Tyrosyl-tRNA synthetase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	U-251	GI50	53200.0	nM	10.1021/acs.jmedchem.0c00193
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	36.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	37.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Apoptotic Cells (%)	59.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Fragmented Nuclei %	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Growth Rate	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Growth Rate	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	87.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	88.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Healthy Nuclei (%)	91.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Membrane Permeable-Phenotype Cells (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	21.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitochondria Different-Phenotype Cells (%)	29.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	62.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	63.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	68.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Mitotic Cells (%)	75.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	99.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	139.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	156.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	178.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	199.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Total Cells	276.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	26.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Control DMSO Tubulin Phenotype Different Cells (%)	31.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Growth Rate	-0.03	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Growth Rate	0.06	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.4	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.44	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.46	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.55	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.59	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.68	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.73	None	10.6019/CHEMBL5058564
Homo sapiens	U2OS	Growth Rate	0.92	None	10.6019/CHEMBL5303304
Homo sapiens	U2OS	Growth Rate	0.94	None	10.6019/CHEMBL5303304
Homo sapiens	U2OS	Growth Rate	1.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	33.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	40.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	42.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	45.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Apoptotic (%)	46.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Fragmented Nuclei (%)	14.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	77.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	82.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	84.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	88.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	91.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Healthy Nuclei (%)	93.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	3.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	11.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	16.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Hoechst High Intensity Objects (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	4.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	6.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	32.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	45.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Membrane Permeable-Phenotype (%)	47.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	8.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	12.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	18.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	19.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	28.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitochondria Different-Phenotype (%)	30.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	53.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	54.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	57.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	60.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	66.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	70.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	85.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Mitotic Cells (%)	100.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	79.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	83.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	86.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	88.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	90.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	91.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	93.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	94.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Normal (%)	96.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	0.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	1.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	2.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	5.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	7.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	9.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	10.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Pyknosed Nuclei (%)	13.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	15.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	17.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	20.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	21.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	24.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	25.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	27.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	34.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	90.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	93.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Population Tubulin-Different-Phenotype (%)	94.0	%	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	95.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	103.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	130.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	132.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	134.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	146.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	148.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	162.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	180.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	210.0	None	10.6019/CHEMBL4689842
Homo sapiens	U2OS	Total Cell Count	244.0	None	10.6019/CHEMBL4689842
Homo sapiens	U5 small nuclear ribonucleoprotein 200 kDa helicase	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	U-87 MG	GI50	nan	None	10.1021/acsmedchemlett.7b00222
Homo sapiens	Uncharacterized aarF domain-containing protein kinase 1	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Uncharacterized aarF domain-containing protein kinase 5	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Uncharacterized protein FLJ45252	Kd	30000.0	nM	10.1126/science.aan4368
Homo sapiens	Vascular endothelial growth factor receptor 2	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Homo sapiens	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Kd	30000.0	nM	10.1126/science.aan4368
Mus musculus	Mus musculus	Activity	nan	None	10.1021/acs.jmedchem.1c00004
Mus musculus	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	IC50	1302.0	nM	10.1021/acs.jmedchem.1c00004
Rattus norvegicus	Cyclooxygenase-1	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Rattus norvegicus	Rattus norvegicus	AUC	422.0	ng.hr.mL-1	10.1016/j.bmc.2018.03.002
Rattus norvegicus	Rattus norvegicus	Cmax	310.52	nM	10.1016/j.bmc.2018.03.002
Rattus norvegicus	Rattus norvegicus	F	39.0	%	10.1016/j.bmc.2018.03.002
Rattus norvegicus	Rattus norvegicus	ID50	1.6	mg.kg-1	10.1021/acsmedchemlett.6b00438
Rattus norvegicus	Rattus norvegicus	T1/2	1.52	hr	10.1016/j.bmc.2018.03.002
Rattus norvegicus	Synaptic vesicular amine transporter	AC50	30000.0	nM	10.1038/s41467-023-40064-9
Severe acute respiratory syndrome coronavirus 2	Replicase polyprotein 1ab	Inhibition	-0.9913	%	10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2	Replicase polyprotein 1ab	Inhibition	9.69	%	10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2	Replicase polyprotein 1ab	Inhibition	30.29	%	10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Hit score	-0.08519	None	10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Hit score	0.4259	None	10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	IC50	19952.62	nM	10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	IC50	20000.0	nM	10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition	-4.09	%	10.21203/rs.3.rs-23951/v1
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition	-0.23	%	10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition	-0.1	%	10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2	Inhibition	0.18	%	10.6019/CHEMBL4495565
None	ADMET	Activity	20.68	g	10.1021/acs.jmedchem.0c01264
None	ADMET	Activity	23.84	g	10.1021/acs.jmedchem.0c01264
None	ADMET	Activity	25.03	g	10.1021/acs.jmedchem.0c01264
None	ADMET	Activity	nan	None	10.1016/j.bmc.2021.116312
None	ADMET	AUC	201.88	ng.hr.mL-1	10.1016/j.bmc.2021.116312
None	ADMET	AUC	512.0	ng.hr.mL-1	10.1021/acsmedchemlett.6b00438
None	ADMET	AUC	924.0	ng.hr.mL-1	10.1021/acsmedchemlett.6b00438
None	ADMET	AUC	1396.0	ng.hr.mL-1	10.1016/j.ejmech.2019.03.005
None	ADMET	AUC	3086.64	ng.hr.mL-1	10.1021/acs.jmedchem.0c01264
None	ADMET	AUC	3191.0	ng.hr.mL-1	10.1016/j.ejmech.2019.03.005
None	ADMET	AUC	3842.73	ng.hr.mL-1	10.1021/acs.jmedchem.0c01264
None	ADMET	CL	0.76	mL.min-1.kg-1	10.1021/acs.jmedchem.0c01264
None	ADMET	CL	3.8	mL.min-1.g-1	10.1021/acs.jmedchem.1c00004
None	ADMET	CL	5.25	uL.min-1.(10^6cells)-1	10.6019/CHEMBL3301361
None	ADMET	CL	19.5	uL.min-1.(10^6cells)-1	10.6019/CHEMBL3301361
None	ADMET	CL	21.5	mL.min-1.kg-1	10.1021/acsmedchemlett.6b00438
None	ADMET	CL	21.88	mL.min-1.g-1	10.6019/CHEMBL3301361
None	ADMET	CL	24.5	mL.min-1.kg-1	10.1016/j.ejmech.2019.03.005
None	ADMET	CL	32.8	mL.min-1.kg-1	10.1021/acsmedchemlett.6b00438
None	ADMET	CL	47.8	mL.min-1.kg-1	10.1021/acs.jmedchem.0c01264
None	ADMET	CL	54.0	mL.min-1.kg-1	10.1021/acs.jmedchem.0c01264
None	ADMET	Cmax	127.63	nM	10.1016/j.bmc.2021.116312
None	ADMET	Cmax	310.0	nM	10.1021/acs.jmedchem.0c01264
None	ADMET	Cmax	500.0	nM	10.1021/acs.jmedchem.0c01264
None	ADMET	Cmax	3460.0	nM	10.1021/acs.jmedchem.0c01264
None	ADMET	Cmax	5577.35	nM	10.1016/j.ejmech.2019.03.005
None	ADMET	Cmax	6980.0	nM	10.1021/acs.jmedchem.0c01264
None	ADMET	Cp	0.02	uM	10.1021/acs.jmedchem.0c01264
None	ADMET	Cp	0.03	uM	10.1021/acs.jmedchem.0c01264
None	ADMET	Cp	0.04	uM	10.1021/acs.jmedchem.0c01264
None	ADMET	Drug metabolism	20.0	%	10.1021/acsmedchemlett.6b00438
None	ADMET	Drug metabolism	21.0	%	10.1021/acsmedchemlett.6b00438
None	ADMET	Drug uptake	0.08	uM	10.1021/acs.jmedchem.0c01264
None	ADMET	Drug uptake	0.14	uM	10.1021/acs.jmedchem.0c01264
None	ADMET	Drug uptake	0.15	uM	10.1021/acs.jmedchem.0c01264
None	ADMET	F	37.6	%	10.1021/acs.jmedchem.0c01264
None	ADMET	F	39.0	%	10.1021/acs.jmedchem.0c01264
None	ADMET	F	45.8	%	10.1016/j.ejmech.2019.03.005
None	ADMET	F	48.0	%	10.1021/acs.jmedchem.0c01264
None	ADMET	F	68.0	%	10.1021/acsmedchemlett.6b00438
None	ADMET	PPB	81.01	%	10.6019/CHEMBL3301361
None	ADMET	Stability	nan	%	10.1021/acs.jmedchem.8b02014
None	ADMET	T1/2	0.43	hr	10.1021/acs.jmedchem.0c01264
None	ADMET	T1/2	0.519	hr	10.1016/j.ejmech.2019.03.005
None	ADMET	T1/2	0.8	hr	10.1021/acsmedchemlett.6b00438
None	ADMET	T1/2	0.83	hr	10.1021/acs.jmedchem.0c01264
None	ADMET	T1/2	1.03	hr	10.1016/j.ejmech.2019.03.005
None	ADMET	T1/2	1.52	hr	10.1021/acs.jmedchem.0c01264
None	ADMET	T1/2	1.6	hr	10.1021/acsmedchemlett.6b00438
None	ADMET	T1/2	1.89	hr	10.1021/acs.jmedchem.0c01264
None	ADMET	T1/2	1.99	hr	10.1021/acs.jmedchem.0c01264
None	ADMET	T1/2	2.31	hr	10.1021/acs.jmedchem.0c01264
None	ADMET	T1/2	2.7	hr	10.1016/j.bmc.2021.116312
None	ADMET	T1/2	6.079	hr	10.1021/acs.jmedchem.1c00004
None	ADMET	Tmax	0.08	hr	10.1021/acs.jmedchem.0c01264
None	ADMET	Tmax	0.25	hr	10.1021/acs.jmedchem.0c01264
None	ADMET	Tmax	0.5	hr	10.1016/j.bmc.2021.116312
None	ADMET	Tmax	1.0	hr	10.1021/acs.jmedchem.0c01264
None	ADMET	Tmax	3.0	hr	10.1021/acs.jmedchem.0c01264
None	ADMET	Vdss	0.73	L.kg-1	10.1021/acs.jmedchem.0c01264
None	ADMET	Vdss	0.884	L.kg-1	10.1016/j.ejmech.2019.03.005
None	ADMET	Vdss	2.49	L.kg-1	10.1021/acs.jmedchem.0c01264
None	Neutrophil	IC50	70.0	nM	10.1016/j.bmcl.2017.06.029
None	Neutrophil	IC50	300.0	nM	10.1016/j.bmcl.2017.06.029
None	Neutrophil	Inhibition	99.6	%	10.1016/j.bmcl.2017.06.029
None	Neutrophil	Inhibition	102.8	%	10.1016/j.bmcl.2017.06.029
None	NON-PROTEIN TARGET	IC50	100.0	nM	10.1021/acs.jnatprod.6b00118
None	NON-PROTEIN TARGET	IC50	300.0	nM	10.1021/acs.jnatprod.6b00118
None	NON-PROTEIN TARGET	IC50	3600.0	nM	10.1021/acsmedchemlett.6b00209
None	NON-PROTEIN TARGET	IC50	6300.0	nM	10.1021/acsmedchemlett.6b00209
None	NON-PROTEIN TARGET	IC50	7900.0	nM	10.1021/acsmedchemlett.6b00209
None	NON-PROTEIN TARGET	IC50	8400.0	nM	10.1021/acsmedchemlett.6b00209
None	NON-PROTEIN TARGET	IC50	10000.0	nM	10.1021/acsmedchemlett.6b00209
None	NON-PROTEIN TARGET	IC50	10600.0	nM	10.1021/acsmedchemlett.6b00209
None	NON-PROTEIN TARGET	ID50	15.0	mg.kg-1	10.1021/acsmedchemlett.6b00438
None	NON-PROTEIN TARGET	Inhibition	100.0	%	10.1021/acs.jnatprod.6b00452
None	NON-PROTEIN TARGET	Inhibition	103.0	%	10.1021/acs.jnatprod.6b00452
None	NON-PROTEIN TARGET	Inhibition	nan	%	10.1021/acs.jnatprod.6b00452
None	NON-PROTEIN TARGET	Vd	2.2	L.kg-1	10.1021/acsmedchemlett.6b00438
None	NON-PROTEIN TARGET	Vd	2.5	L.kg-1	10.1021/acsmedchemlett.6b00438
None	No relevant target	LogD7.4	2.72	None	10.6019/CHEMBL3301361
None	Unchecked	Activity	0.5	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	1.14	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	1.49	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	2.6	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	3.44	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	5.71	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	7.95	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	9.19	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	10.1	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	12.4	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	13.6	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	13.9	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	14.8	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	18.2	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	31.7	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	32.8	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	32.9	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	47.9	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	48.4	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	49.6	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	73.2	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	74.6	%	10.1016/j.ejmech.2021.113661
None	Unchecked	Activity	77.0	%	10.1016/j.ejmech.2021.113661
None	Unchecked	IC50	5.49	nM	10.1016/j.bmcl.2017.03.020
None	Unchecked	IC50	337.0	nM	10.1021/acs.jmedchem.8b02014
None	Unchecked	IC50	846.0	nM	10.1021/acs.jmedchem.8b01298
None	Unchecked	IC50	10000.0	nM	10.1016/j.ejmech.2016.11.014
None	Unchecked	IC50	10000.0	nM	10.1039/C2MD20044A
None	Unchecked	IC50	13300.0	nM	10.1016/j.bmcl.2023.129152
None	Unchecked	IC50	20000.0	nM	10.1021/acs.jmedchem.9b00969
None	Unchecked	IC50	978000.0	nM	10.1021/ml500354e
None	Unchecked	Kd	30000.0	nM	10.1126/science.aan4368
None	Unchecked	Ratio IC50	2.5	None	None
None	Unchecked	Ratio IC50	7.2	None	10.1016/j.bmc.2022.117028
None	Unchecked	Ratio IC50	11.0	None	10.1021/acs.jmedchem.0c01544
None	Unchecked	Ratio IC50	19.0	None	10.1039/C8MD00556G
None	Unchecked	Ratio IC50	20.0	None	10.1021/acs.jmedchem.7b00618
None	Unchecked	Ratio IC50	21.0	None	10.1021/jm300847w
None	Unchecked	Ratio IC50	25.37	None	10.1016/j.bmc.2021.116312
None	Unchecked	Ratio IC50	33.0	None	10.1016/j.bmc.2019.05.043
None	Unchecked	Ratio IC50	35.0	None	10.1016/j.ejmech.2019.03.005
None	Unchecked	Ratio IC50	36.0	None	10.1021/jm301522m
None	Unchecked	Ratio IC50	49.0	None	10.1021/jm300847w
None	Unchecked	Ratio IC50	65.0	None	10.1021/acs.jmedchem.0c01544
None	Unchecked	Ratio IC50	67.0	None	10.1016/j.bmc.2022.117028
None	Unchecked	Ratio IC50	80.0	None	10.1016/j.ejmech.2018.03.068
None	Unchecked	Ratio IC50	85.0	None	10.1016/j.ejmech.2019.03.005
None	Unchecked	Ratio IC50	86.0	None	10.1016/j.ejmech.2018.03.068
None	Unchecked	Ratio IC50	88.0	None	10.1039/C8MD00556G
None	Unchecked	Ratio IC50	100.0	None	10.1016/j.bmc.2019.05.043
None	Unchecked	Ratio IC50	106.0	None	10.1016/j.bmcl.2020.127479
None	Unchecked	Ratio IC50	141.0	None	10.1021/acs.jmedchem.0c01544
None	Unchecked	Ratio IC50	225.0	None	10.1021/jm301522m
None	Unchecked	Ratio IC50	230.0	None	10.1021/acs.jmedchem.8b01298
None	Unchecked	Ratio IC50	248.0	None	10.1021/jm300847w
None	Unchecked	Ratio IC50	257.0	None	10.1039/C8MD00556G
None	Unchecked	Ratio IC50	328.0	None	10.1021/jm301522m
None	Unchecked	Ratio IC50	330.0	None	10.1021/acs.jmedchem.8b01298
None	Unchecked	Ratio IC50	460.0	None	10.1016/j.ejmech.2018.03.068
None	Unchecked	Ratio IC50	1202.0	None	10.1016/j.ejmech.2019.03.005