Navigation

name Structure Reference Source Properties Activities Metabolism

1-(butan-2-yl)-4-{4-[4-(4-{[2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one

AlkaPlorer ID: AK322949

Synonym: None

IUPAC Name: 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one

Structure

SMILES: CCC(C)N1N=CN(C2=CC=C(N3CCN(C4=CC=C(OCC5COC(CN6C=NC=N6)(C6=CC=C(Cl)C=C6Cl)O5)C=C4)CC3)C=C2)C1=O

copy

InChI: InChI=1S/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3

copy

InChIKey: VHVPQPYKVGDNFY-UHFFFAOYSA-N

copy

Reference

PubChem CID: 3793

CAS: 84625-61-6

NPASS: NPC479799

COCONUT: CNP0389569.1

Source

Species Genus Family Order Class Phylum Kingdom Domain
Dendrodochium sp. Dendrodochium Bionectriaceae Hypocreales Sordariomycetes Ascomycota Fungi Eukaryota

Properties Information

Molecule Weight: 705.6470000000002

TPSA？: 104.70000000000002

MolLogP？: 5.5773000000000055

Number of H-Donors: 0

Number of H-Acceptors: 12

RingCount: 7

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Absidia Absidia Activity 50.0 % 10.1128/aac.00452-07
Absidia Absidia Activity nan None 10.1128/aac.00452-07
Absidia Absidia MFC 2.0 ug ml-1 10.1128/aac.00662-08
Absidia Absidia MIC50 1.0 ug.mL-1 10.1128/aac.01539-06
Absidia Absidia MIC90 16.0 ug.mL-1 10.1128/aac.01539-06
Acinetobacter baumannii Acinetobacter baumannii MIC 10000.0 nM 10.6019/CHEMBL4513141
Acinetobacter baumannii Acinetobacter baumannii MIC 20000.0 nM 10.6019/CHEMBL4513161
Alternaria alternata Alternaria alternata MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Alternaria alternata Alternaria alternata MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Apophysomyces elegans Apophysomyces elegans Activity 80.0 % 10.1128/aac.00452-07
Apophysomyces elegans Apophysomyces elegans MIC50 0.125 ug.mL-1 10.1128/aac.00452-07
Arthrodermataceae Arthrodermataceae GMMIC 0.89 ug ml-1 10.1016/s0960-894x(02)00282-2
Arthrodermataceae Arthrodermataceae MFC 1.4 ug ml-1 10.1021/jm800009r
Arthrodermataceae Arthrodermataceae MFC50 1.0 ug ml-1 10.1021/jm800009r
Arthrodermataceae Arthrodermataceae MFC90 2.0 ug ml-1 10.1021/jm800009r
Arthrodermataceae Arthrodermataceae MIC 0.14 ug.mL-1 10.1021/jm800009r
Arthrodermataceae Arthrodermataceae MIC50 0.125 ug.mL-1 10.1021/jm800009r
Arthrodermataceae Arthrodermataceae MIC90 0.25 ug.mL-1 10.1021/jm800009r
Aspergillus Aspergillus MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Aspergillus Aspergillus MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Aspergillus flavus Aspergillus flavus IZ 22.0 mm 10.1007/s00044-012-0154-3
Aspergillus flavus Aspergillus flavus IZ 25.0 mm 10.1016/j.ejmech.2012.02.030
Aspergillus flavus Aspergillus flavus MFC 0.5 ug ml-1 10.1128/aac.00662-08
Aspergillus flavus Aspergillus flavus MIC 0.031 ug.mL-1 10.1016/j.ejmech.2022.114161
Aspergillus flavus Aspergillus flavus MIC 0.125 ug.mL-1 10.1016/j.bmcl.2011.06.062
Aspergillus flavus Aspergillus flavus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2010.10.019
Aspergillus flavus Aspergillus flavus MIC 0.125 ug.mL-1 10.1039/C8MD00155C
Aspergillus flavus Aspergillus flavus MIC 0.25 ug.mL-1 10.1128/aac.01176-06
Aspergillus flavus Aspergillus flavus MIC 0.48 ug.mL-1 10.1016/j.bmc.2016.06.010
Aspergillus flavus Aspergillus flavus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2009.02.036
Aspergillus flavus Aspergillus flavus MIC 0.5 ug.mL-1 10.1128/aac.01176-06
Aspergillus flavus Aspergillus flavus MIC 0.59 ug.mL-1 10.1128/aac.00662-08
Aspergillus flavus Aspergillus flavus MIC 1.56 ug.mL-1 10.1007/s00044-012-0154-3
Aspergillus flavus Aspergillus flavus MIC 6.25 ug.mL-1 10.1016/j.ejmech.2019.03.023
Aspergillus flavus Aspergillus flavus MIC 40.0 nM 10.1021/jm900760k
Aspergillus flavus Aspergillus flavus MIC 80.0 ug.mL-1 10.1021/jm00020a005
Aspergillus flavus Aspergillus flavus MIC 8860.0 nM 10.1016/j.ejmech.2012.02.030
Aspergillus flavus Aspergillus flavus MIC 16000.0 ug.mL-1 10.1016/j.ejmech.2006.09.010
Aspergillus flavus Aspergillus flavus MIC50 0.25 ug.mL-1 10.1128/aac.01543-08
Aspergillus flavus Aspergillus flavus MIC50 680.0 nM 10.1016/j.ejmech.2017.03.075
Aspergillus flavus Aspergillus flavus MIC90 0.1 ug.mL-1 10.1016/j.ejmech.2013.06.018
Aspergillus flavus Aspergillus flavus MIC90 0.5 ug.mL-1 10.1128/aac.01543-08
Aspergillus fumigatus Aspergillus fumigatus Activity nan None 10.1128/aac.00692-10
Aspergillus fumigatus Aspergillus fumigatus IC80 0.0004 ug ml-1 10.1016/S0960-894X(01)80190-6
Aspergillus fumigatus Aspergillus fumigatus IC80 0.02 ug ml-1 10.1016/S0960-894X(01)80190-6
Aspergillus fumigatus Aspergillus fumigatus Inhibition nan % 10.1128/aac.00692-10
Aspergillus fumigatus Aspergillus fumigatus IZ 23.0 mm 10.1016/j.ejmech.2012.02.030
Aspergillus fumigatus Aspergillus fumigatus IZ 27.4 mm 10.1016/j.ejmech.2016.11.019
Aspergillus fumigatus Aspergillus fumigatus IZ 28.0 mm 10.1016/j.ejmech.2011.07.035
Aspergillus fumigatus Aspergillus fumigatus IZ 28.0 mm 10.1016/j.ejmech.2011.08.018
Aspergillus fumigatus Aspergillus fumigatus IZ 30.0 mm 10.1007/s00044-012-0154-3
Aspergillus fumigatus Aspergillus fumigatus MFC 2.0 ug ml-1 10.1128/aac.00662-08
Aspergillus fumigatus Aspergillus fumigatus MFC nan None None
Aspergillus fumigatus Aspergillus fumigatus MIC 0.031 ug.mL-1 10.1016/j.ejmech.2022.114161
Aspergillus fumigatus Aspergillus fumigatus MIC 0.053 ug.mL-1 10.1128/aac.00316-10
Aspergillus fumigatus Aspergillus fumigatus MIC 0.0625 ug.mL-1 10.1016/j.bmc.2012.04.045
Aspergillus fumigatus Aspergillus fumigatus MIC 0.12 ug.mL-1 10.1016/j.bmcl.2005.05.080
Aspergillus fumigatus Aspergillus fumigatus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2019.05.047
Aspergillus fumigatus Aspergillus fumigatus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113715
Aspergillus fumigatus Aspergillus fumigatus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113955
Aspergillus fumigatus Aspergillus fumigatus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113987
Aspergillus fumigatus Aspergillus fumigatus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2022.114195
Aspergillus fumigatus Aspergillus fumigatus MIC 0.125 ug.mL-1 10.1128/aac.00931-09
Aspergillus fumigatus Aspergillus fumigatus MIC 0.125 ug.mL-1 10.1128/aac.00942-07
Aspergillus fumigatus Aspergillus fumigatus MIC 0.125 ug.mL-1 10.1128/aac.01599-09
Aspergillus fumigatus Aspergillus fumigatus MIC 0.14 ug.mL-1 10.1016/0960-894X(96)00363-0
Aspergillus fumigatus Aspergillus fumigatus MIC 0.15 ug.mL-1 10.1021/jm00020a005
Aspergillus fumigatus Aspergillus fumigatus MIC 0.17 ug.mL-1 10.1016/j.ejmech.2010.06.029
Aspergillus fumigatus Aspergillus fumigatus MIC 0.19 ug.mL-1 10.1016/0960-894X(96)00363-0
Aspergillus fumigatus Aspergillus fumigatus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2008.10.055
Aspergillus fumigatus Aspergillus fumigatus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2009.02.036
Aspergillus fumigatus Aspergillus fumigatus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2011.06.062
Aspergillus fumigatus Aspergillus fumigatus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2016.02.013
Aspergillus fumigatus Aspergillus fumigatus MIC 0.25 ug.mL-1 10.1128/aac.00692-10
Aspergillus fumigatus Aspergillus fumigatus MIC 0.25 ug.mL-1 10.1128/aac.01492-08
Aspergillus fumigatus Aspergillus fumigatus MIC 0.25 ug.mL-1 10.1128/aac.01599-09
Aspergillus fumigatus Aspergillus fumigatus MIC 0.32 ug.mL-1 10.1128/aac.00156-08
Aspergillus fumigatus Aspergillus fumigatus MIC 0.39 ug.mL-1 10.1016/0960-894X(96)00363-0
Aspergillus fumigatus Aspergillus fumigatus MIC 0.42 ug.mL-1 10.1016/j.bmcl.2009.08.089
Aspergillus fumigatus Aspergillus fumigatus MIC 0.42 ug.mL-1 10.1016/j.ejmech.2020.112082
Aspergillus fumigatus Aspergillus fumigatus MIC 0.42 ug.mL-1 10.1021/ml300429p
Aspergillus fumigatus Aspergillus fumigatus MIC 0.46 ug.mL-1 10.1128/aac.00662-08
Aspergillus fumigatus Aspergillus fumigatus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2007.04.038
Aspergillus fumigatus Aspergillus fumigatus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2008.10.055
Aspergillus fumigatus Aspergillus fumigatus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2020.112082
Aspergillus fumigatus Aspergillus fumigatus MIC 0.5 ug.mL-1 10.1021/np4001703
Aspergillus fumigatus Aspergillus fumigatus MIC 0.5 ug.mL-1 10.1128/aac.01599-09
Aspergillus fumigatus Aspergillus fumigatus MIC 0.71 ug.mL-1 10.1128/aac.00316-10
Aspergillus fumigatus Aspergillus fumigatus MIC 0.85 ug.mL-1 10.1128/aac.00316-10
Aspergillus fumigatus Aspergillus fumigatus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2008.04.056
Aspergillus fumigatus Aspergillus fumigatus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2015.04.047
Aspergillus fumigatus Aspergillus fumigatus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2017.05.043
Aspergillus fumigatus Aspergillus fumigatus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2020.112046
Aspergillus fumigatus Aspergillus fumigatus MIC 1.0 ug.mL-1 10.1039/C7MD00442G
Aspergillus fumigatus Aspergillus fumigatus MIC 1.0 ug.mL-1 10.1128/aac.01599-09
Aspergillus fumigatus Aspergillus fumigatus MIC 2.0 ug.mL-1 10.1016/j.ejmech.2010.07.002
Aspergillus fumigatus Aspergillus fumigatus MIC 4.0 ug.mL-1 10.1016/j.bmc.2016.11.051
Aspergillus fumigatus Aspergillus fumigatus MIC 4.0 ug.mL-1 10.1016/j.bmc.2018.04.054
Aspergillus fumigatus Aspergillus fumigatus MIC 4.0 ug.mL-1 10.1016/j.bmcl.2019.07.037
Aspergillus fumigatus Aspergillus fumigatus MIC 4.0 ug.mL-1 10.1016/j.ejmech.2014.02.019
Aspergillus fumigatus Aspergillus fumigatus MIC 4.0 ug.mL-1 10.1016/j.ejmech.2016.07.067
Aspergillus fumigatus Aspergillus fumigatus MIC 4.0 ug.mL-1 10.1128/aac.00692-10
Aspergillus fumigatus Aspergillus fumigatus MIC 4.0 ug.mL-1 10.1128/aac.01599-09
Aspergillus fumigatus Aspergillus fumigatus MIC 6.25 ug.mL-1 10.1007/s00044-012-0154-3
Aspergillus fumigatus Aspergillus fumigatus MIC 6.25 ug.mL-1 10.1016/j.ejmech.2019.03.023
Aspergillus fumigatus Aspergillus fumigatus MIC 8.0 ug.mL-1 10.1128/aac.01092-06
Aspergillus fumigatus Aspergillus fumigatus MIC 8.0 ug.mL-1 10.1128/aac.01599-09
Aspergillus fumigatus Aspergillus fumigatus MIC 16.0 ug.mL-1 10.1128/aac.00156-08
Aspergillus fumigatus Aspergillus fumigatus MIC 16.0 ug.mL-1 10.1128/aac.00931-09
Aspergillus fumigatus Aspergillus fumigatus MIC 16.0 ug.mL-1 10.1128/aac.01492-08
Aspergillus fumigatus Aspergillus fumigatus MIC 16.0 ug.mL-1 10.1128/aac.01599-09
Aspergillus fumigatus Aspergillus fumigatus MIC 40.0 nM 10.1021/jm900760k
Aspergillus fumigatus Aspergillus fumigatus MIC 71.0 ug.mL-1 10.1021/ml300429p
Aspergillus fumigatus Aspergillus fumigatus MIC 100.0 ug.mL-1 10.1016/j.ejmech.2020.112082
Aspergillus fumigatus Aspergillus fumigatus MIC 350.0 nM 10.1021/jm900760k
Aspergillus fumigatus Aspergillus fumigatus MIC 552.0 nM 10.1039/d2md00138a
Aspergillus fumigatus Aspergillus fumigatus MIC 1000.0 nM 10.1016/s0960-894x(00)00445-5
Aspergillus fumigatus Aspergillus fumigatus MIC 1000.0 nM 10.1016/s0960-894x(00)00551-5
Aspergillus fumigatus Aspergillus fumigatus MIC 8860.0 nM 10.1016/j.ejmech.2012.02.030
Aspergillus fumigatus Aspergillus fumigatus MIC 16000.0 ug.mL-1 10.1016/j.ejmech.2006.09.010
Aspergillus fumigatus Aspergillus fumigatus MIC=>50 0.25 ug ml-1 10.1021/acs.jmedchem.1c00883
Aspergillus fumigatus Aspergillus fumigatus MIC=>50 16.0 ug ml-1 10.1021/acs.jmedchem.1c00883
Aspergillus fumigatus Aspergillus fumigatus MIC50 0.125 ug.mL-1 10.1128/aac.00234-08
Aspergillus fumigatus Aspergillus fumigatus MIC50 0.25 ug.mL-1 10.1128/aac.01543-08
Aspergillus fumigatus Aspergillus fumigatus MIC50 0.5 ug.mL-1 10.1128/aac.00234-08
Aspergillus fumigatus Aspergillus fumigatus MIC50 0.5 ug.mL-1 10.1128/aac.01492-08
Aspergillus fumigatus Aspergillus fumigatus MIC50 1.0 ug.mL-1 10.1021/acs.jmedchem.2c00595
Aspergillus fumigatus Aspergillus fumigatus MIC50 1.0 ug.mL-1 10.1128/aac.00234-08
Aspergillus fumigatus Aspergillus fumigatus MIC50 2.0 ug.mL-1 10.1128/aac.00234-08
Aspergillus fumigatus Aspergillus fumigatus MIC50 32.0 ug.mL-1 10.1021/acs.jmedchem.2c00595
Aspergillus fumigatus Aspergillus fumigatus MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2011.06.008
Aspergillus fumigatus Aspergillus fumigatus MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2012.02.042
Aspergillus fumigatus Aspergillus fumigatus MIC80 0.0625 ug.mL-1 10.1016/j.ejmech.2011.02.001
Aspergillus fumigatus Aspergillus fumigatus MIC80 0.42 ug.mL-1 10.1016/j.bmcl.2008.02.027
Aspergillus fumigatus Aspergillus fumigatus MIC80 0.42 ug.mL-1 10.1016/j.bmcl.2008.11.101
Aspergillus fumigatus Aspergillus fumigatus MIC80 0.5 ug.mL-1 10.1016/j.bmcl.2009.01.048
Aspergillus fumigatus Aspergillus fumigatus MIC80 0.5 ug.mL-1 10.1016/j.ejmech.2008.11.007
Aspergillus fumigatus Aspergillus fumigatus MIC80 1.0 ug.mL-1 10.1016/j.bmcl.2010.03.014
Aspergillus fumigatus Aspergillus fumigatus MIC80 1.0 ug.mL-1 10.1016/j.bmcl.2010.12.006
Aspergillus fumigatus Aspergillus fumigatus MIC80 1.0 ug.mL-1 10.1016/j.bmcl.2013.11.037
Aspergillus fumigatus Aspergillus fumigatus MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2007.01.006
Aspergillus fumigatus Aspergillus fumigatus MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2011.02.042
Aspergillus fumigatus Aspergillus fumigatus MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2011.04.022
Aspergillus fumigatus Aspergillus fumigatus MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2014.05.079
Aspergillus fumigatus Aspergillus fumigatus MIC80 1.0 ug.mL-1 10.1021/jm051211n
Aspergillus fumigatus Aspergillus fumigatus MIC80 2.0 ug.mL-1 10.1016/j.bmcl.2009.07.144
Aspergillus fumigatus Aspergillus fumigatus MIC80 2.0 ug.mL-1 10.1016/j.ejmech.2009.05.018
Aspergillus fumigatus Aspergillus fumigatus MIC80 2.0 ug.mL-1 10.1039/C3MD20086H
Aspergillus fumigatus Aspergillus fumigatus MIC80 8.0 ug.mL-1 10.1016/j.ejmech.2014.01.009
Aspergillus fumigatus Aspergillus fumigatus MIC80 8.0 ug.mL-1 10.1016/j.ejmech.2017.10.043
Aspergillus fumigatus Aspergillus fumigatus MIC80 32.0 ug.mL-1 10.1021/np500024r
Aspergillus fumigatus Aspergillus fumigatus MIC90 0.2 ug.mL-1 10.1016/j.ejmech.2013.06.018
Aspergillus fumigatus Aspergillus fumigatus MIC90 0.25 ug.mL-1 10.1128/aac.00234-08
Aspergillus fumigatus Aspergillus fumigatus MIC90 0.5 ug.mL-1 10.1128/aac.00156-08
Aspergillus fumigatus Aspergillus fumigatus MIC90 0.5 ug.mL-1 10.1128/aac.01492-08
Aspergillus fumigatus Aspergillus fumigatus MIC90 0.5 ug.mL-1 10.1128/aac.01543-08
Aspergillus fumigatus Aspergillus fumigatus MIC90 1.0 ug.mL-1 10.1128/aac.00234-08
Aspergillus fumigatus Aspergillus fumigatus MIC90 2.0 ug.mL-1 10.1128/aac.00234-08
Aspergillus fumigatus Aspergillus fumigatus MIC90 4.0 ug.mL-1 10.1128/aac.00234-08
Aspergillus nidulans Aspergillus nidulans MIC 0.195 ug.mL-1 10.1016/j.bmc.2016.06.010
Aspergillus nidulans Aspergillus nidulans MIC 1.0 ug.mL-1 10.1128/aac.00692-10
Aspergillus nidulans Aspergillus nidulans MIC 1.95 ug.mL-1 10.1021/acs.jmedchem.5b01375
Aspergillus nidulans Aspergillus nidulans MIC 35400.0 nM 10.1021/jm031089x
Aspergillus nidulans Aspergillus nidulans MIC50 0.25 ug.mL-1 10.1128/aac.01543-08
Aspergillus nidulans Aspergillus nidulans MIC50 280.0 nM 10.1016/j.ejmech.2017.03.075
Aspergillus nidulans Aspergillus nidulans MIC90 0.5 ug.mL-1 10.1128/aac.01543-08
Aspergillus niger Aspergillus niger IZ 17.0 mm 10.1007/s00044-012-0331-4
Aspergillus niger Aspergillus niger IZ 25.0 mm 10.1007/s00044-010-9354-x
Aspergillus niger Aspergillus niger MFC 4.0 ug ml-1 10.1128/aac.00662-08
Aspergillus niger Aspergillus niger MIC 0.007 ug.mL-1 10.1016/j.ejmech.2019.03.023
Aspergillus niger Aspergillus niger MIC 0.125 ug.mL-1 10.1016/j.ejmech.2010.10.019
Aspergillus niger Aspergillus niger MIC 0.14 ug.mL-1 10.1128/aac.00585-09
Aspergillus niger Aspergillus niger MIC 0.5 ug.mL-1 10.1021/np500080m
Aspergillus niger Aspergillus niger MIC 0.5 ug.mL-1 10.1128/aac.00585-09
Aspergillus niger Aspergillus niger MIC 0.98 ug.mL-1 10.1128/aac.00662-08
Aspergillus niger Aspergillus niger MIC 1.0 ug.mL-1 10.1128/aac.00585-09
Aspergillus niger Aspergillus niger MIC 2.0 ug.mL-1 10.1128/aac.00692-10
Aspergillus niger Aspergillus niger MIC 4.75 ug.mL-1 10.1128/aac.00585-09
Aspergillus niger Aspergillus niger MIC 6.25 ug.mL-1 10.1007/s00044-010-9354-x
Aspergillus niger Aspergillus niger MIC 80.0 ug.mL-1 10.1021/jm00020a005
Aspergillus niger Aspergillus niger MIC 350.0 nM 10.1021/jm900760k
Aspergillus niger Aspergillus niger MIC 17700.0 nM 10.1021/jm031089x
Aspergillus niger Aspergillus niger MIC50 1.0 ug.mL-1 10.1128/aac.01543-08
Aspergillus niger Aspergillus niger MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Aspergillus ochraceus Aspergillus ochraceus MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Aspergillus ochraceus Aspergillus ochraceus MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Aspergillus sp. Aspergillus sp. GMMIC 0.3 ug ml-1 10.1016/s0960-894x(02)00282-2
Aspergillus sp. Aspergillus sp. MIC 0.008 ug.mL-1 10.1128/aac.01475-07
Aspergillus sp. Aspergillus sp. MIC50 0.03 ug.mL-1 10.1128/aac.01475-07
Aspergillus sp. Aspergillus sp. MIC50 0.32 ug.mL-1 10.1021/jm0494772
Aspergillus sp. Aspergillus sp. MIC90 0.06 ug.mL-1 10.1128/aac.01475-07
Aspergillus sp. Aspergillus sp. MIC90 1.184 ug.mL-1 10.1021/jm0494772
Aspergillus sydowii Aspergillus sydowii MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Aspergillus sydowii Aspergillus sydowii MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Aspergillus terreus Aspergillus terreus MFC 0.5 ug ml-1 10.1128/aac.00662-08
Aspergillus terreus Aspergillus terreus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2010.10.019
Aspergillus terreus Aspergillus terreus MIC 0.58 ug.mL-1 10.1128/aac.00662-08
Aspergillus terreus Aspergillus terreus MIC 0.975 ug.mL-1 10.1016/j.bmc.2016.06.010
Aspergillus terreus Aspergillus terreus MIC 350.0 nM 10.1021/jm900760k
Aspergillus terreus Aspergillus terreus MIC50 0.125 ug.mL-1 10.1128/aac.00335-08
Aspergillus terreus Aspergillus terreus MIC50 0.25 ug.mL-1 10.1128/aac.01543-08
Aspergillus terreus Aspergillus terreus MIC50 1400.0 nM 10.1016/j.ejmech.2017.03.075
Aspergillus terreus Aspergillus terreus MIC90 0.5 ug.mL-1 10.1128/aac.00335-08
Aspergillus terreus Aspergillus terreus MIC90 0.5 ug.mL-1 10.1128/aac.01543-08
Aspergillus tubingensis Aspergillus tubingensis MIC 0.5 ug.mL-1 10.1128/aac.00585-09
Aspergillus tubingensis Aspergillus tubingensis MIC 0.75 ug.mL-1 10.1128/aac.00585-09
Aspergillus tubingensis Aspergillus tubingensis MIC 1.0 ug.mL-1 10.1128/aac.00585-09
Aspergillus tubingensis Aspergillus tubingensis MIC 3.67 ug.mL-1 10.1128/aac.00585-09
Aspergillus tubingensis Aspergillus tubingensis MIC 4.0 ug.mL-1 10.1128/aac.00585-09
Aspergillus tubingensis Aspergillus tubingensis MIC 11.0 ug.mL-1 10.1128/aac.00585-09
Aspergillus tubingensis Aspergillus tubingensis MIC 16.0 ug.mL-1 10.1128/aac.00585-09
Aspergillus versicolor Aspergillus versicolor MIC 20.0 nM 10.1021/jm900760k
Aspergillus versicolor Aspergillus versicolor MIC 350.0 nM 10.1021/jm900760k
Aspergillus versicolor Aspergillus versicolor MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Aspergillus versicolor Aspergillus versicolor MIC90 1.0 ug.mL-1 10.1128/aac.01543-08
Aureobasidium pullulans Aureobasidium pullulans MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
Aureobasidium pullulans Aureobasidium pullulans MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Beauveria bassiana Beauveria bassiana MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Beauveria bassiana Beauveria bassiana MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Bos taurus Progesterone receptor IC50 nan None None
Bos taurus Progesterone receptor Ki nan None None
Candida Candida GMMIC 0.04 ug ml-1 10.1016/s0960-894x(02)00282-2
Candida Candida MIC 0.02 ug.mL-1 10.1016/j.bmcl.2014.01.060
Candida Candida MIC 0.03 ug.mL-1 10.1016/j.bmcl.2005.05.080
Candida Candida MIC 0.04 ug.mL-1 10.1016/j.bmcl.2014.01.060
Candida Candida MIC 0.09 ug.mL-1 10.1016/j.bmcl.2014.01.060
Candida Candida MIC 0.19 ug.mL-1 10.1016/j.bmcl.2014.01.060
Candida Candida MIC 0.25 ug.mL-1 10.1016/j.bmcl.2005.05.080
Candida Candida MIC 0.25 ug.mL-1 10.1016/j.bmcl.2014.01.060
Candida Candida MIC 0.39 ug.mL-1 10.1016/j.bmcl.2014.01.060
Candida Candida MIC 2.0 ug.mL-1 10.1016/j.bmc.2012.04.045
Candida Candida MIC50 0.016 ug.mL-1 10.1128/aac.01217-06
Candida Candida MIC50 0.1 ug.mL-1 10.1021/jm0494772
Candida Candida MIC50 32.0 ug.mL-1 10.1128/aac.00459-07
Candida Candida MIC90 0.25 ug.mL-1 10.1128/aac.01217-06
Candida Candida MIC90 17.0 ug.mL-1 10.1021/jm0494772
Candida albicans Candida albicans Activity 0.0 % 10.1128/aac.00323-08
Candida albicans Candida albicans Activity 1.4 None 10.1128/aac.01070-07
Candida albicans Candida albicans Activity 2.0 % 10.1128/aac.00323-08
Candida albicans Candida albicans Activity 2.12 None 10.1128/aac.01070-07
Candida albicans Candida albicans Activity 2.13 None 10.1128/aac.01070-07
Candida albicans Candida albicans Activity 2.46 None 10.1128/aac.01070-07
Candida albicans Candida albicans Activity 8.3 % 10.1128/aac.00303-10
Candida albicans Candida albicans Activity 16.7 % 10.1128/aac.00303-10
Candida albicans Candida albicans Activity 25.0 % 10.1128/aac.00303-10
Candida albicans Candida albicans Activity 29.0 % 10.1128/aac.00303-10
Candida albicans Candida albicans Activity 33.0 % 10.1128/aac.00303-10
Candida albicans Candida albicans Activity 38.0 % 10.1128/aac.00303-10
Candida albicans Candida albicans Activity 48.1 % 10.1128/aac.01475-07
Candida albicans Candida albicans Activity 50.0 % 10.1128/aac.00303-10
Candida albicans Candida albicans Activity 50.0 % 10.1128/aac.01475-07
Candida albicans Candida albicans Activity 98.0 % 10.1128/aac.00323-08
Candida albicans Candida albicans Activity nan None 10.1128/aac.00730-10
Candida albicans Candida albicans ED50 5.19 mg.kg-1 10.1016/j.ejmech.2022.114161
Candida albicans Candida albicans ED50 19.0 mg.kg-1 10.1016/j.ejmech.2022.114161
Candida albicans Candida albicans FC 1.0 None 10.1128/aac.01645-09
Candida albicans Candida albicans FC 2.0 None 10.1128/aac.01645-09
Candida albicans Candida albicans FC 8.0 None 10.1128/aac.01645-09
Candida albicans Candida albicans FC 16.0 None 10.1128/aac.01645-09
Candida albicans Candida albicans FICI 0.005 None 10.1128/aac.01497-08
Candida albicans Candida albicans IC50 1390.0 nM 10.1128/aac.00730-10
Candida albicans Candida albicans IC50 1410.0 nM 10.1128/aac.00730-10
Candida albicans Candida albicans IC80 0.0012 ug ml-1 10.1016/S0960-894X(01)80190-6
Candida albicans Candida albicans IC80 0.0056 ug ml-1 10.1016/S0960-894X(01)80190-6
Candida albicans Candida albicans IC80 0.03 ug ml-1 10.1016/S0960-894X(01)80190-6
Candida albicans Candida albicans IZ 2.62 mm 10.1007/s00044-013-0573-9
Candida albicans Candida albicans IZ 2.67 mm 10.1007/s00044-013-0543-2
Candida albicans Candida albicans IZ 5.35 mm 10.1007/s00044-013-0543-2
Candida albicans Candida albicans IZ 5.35 mm 10.1007/s00044-013-0573-9
Candida albicans Candida albicans IZ 12.01 mm 10.1007/s00044-013-0543-2
Candida albicans Candida albicans IZ 12.01 mm 10.1007/s00044-013-0573-9
Candida albicans Candida albicans IZ 20.0 mm 10.1007/s00044-012-0331-4
Candida albicans Candida albicans IZ 21.0 mm 10.1021/np100175x
Candida albicans Candida albicans IZ 23.04 mm 10.1007/s00044-013-0543-2
Candida albicans Candida albicans IZ 23.06 mm 10.1039/C0MD00074D
Candida albicans Candida albicans IZ 25.12 mm 10.1007/s00044-013-0573-9
Candida albicans Candida albicans IZ 25.2 mm 10.1016/j.ejmech.2016.11.019
Candida albicans Candida albicans IZ 26.0 mm 10.1016/j.ejmech.2011.07.035
Candida albicans Candida albicans IZ 26.0 mm 10.1016/j.ejmech.2011.08.018
Candida albicans Candida albicans IZ 27.0 mm 10.1007/s00044-010-9354-x
Candida albicans Candida albicans MBIC50 16.0 ug ml-1 10.1016/j.ejmech.2021.113740
Candida albicans Candida albicans MBIC50 32.0 ug ml-1 10.1016/j.ejmech.2021.113740
Candida albicans Candida albicans MBIC50 64.0 ug ml-1 10.1016/j.ejmech.2021.113740
Candida albicans Candida albicans MFC 0.06 ug ml-1 10.1128/aac.00662-08
Candida albicans Candida albicans MFC 1.0 ug ml-1 10.1021/jm800009r
Candida albicans Candida albicans MFC 16.0 ug ml-1 10.1016/j.ejmech.2021.113740
Candida albicans Candida albicans MFC 256.0 ug ml-1 10.1016/j.ejmech.2013.10.051
Candida albicans Candida albicans MFC nan None None
Candida albicans Candida albicans MFC50 1.0 ug ml-1 10.1021/jm800009r
Candida albicans Candida albicans MFC90 1.0 ug ml-1 10.1021/jm800009r
Candida albicans Candida albicans MIC 0.007 ug.mL-1 10.1016/j.ejmech.2019.03.023
Candida albicans Candida albicans MIC 0.007 ug.mL-1 10.1016/j.ejmech.2019.07.003
Candida albicans Candida albicans MIC 0.008 ug.mL-1 10.1128/aac.01070-07
Candida albicans Candida albicans MIC 0.008 ug.mL-1 10.1128/aac.01475-07
Candida albicans Candida albicans MIC 0.015 ug.mL-1 10.1128/aac.00323-08
Candida albicans Candida albicans MIC 0.015 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC 0.0156 ug.mL-1 10.1128/aac.01645-09
Candida albicans Candida albicans MIC 0.016 ug.mL-1 10.1128/aac.00182-07
Candida albicans Candida albicans MIC 0.016 ug.mL-1 10.1128/aac.00940-08
Candida albicans Candida albicans MIC 0.016 ug.mL-1 10.1128/aac.01070-07
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1016/j.bmcl.2005.05.080
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1016/j.ejmech.2015.04.047
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1016/j.ejmech.2016.02.013
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1016/j.ejmech.2019.05.047
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1016/j.ejmech.2019.111689
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1016/j.ejmech.2021.113715
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1016/j.ejmech.2021.113740
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1016/j.ejmech.2021.113955
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1016/j.ejmech.2021.113987
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1016/j.ejmech.2022.114195
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1021/jm00020a005
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1039/C7MD00442G
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1128/aac.01292-08
Candida albicans Candida albicans MIC 0.03 ug.mL-1 10.1128/aac.01368-08
Candida albicans Candida albicans MIC 0.031 ug.mL-1 10.1016/j.bmcl.2008.10.055
Candida albicans Candida albicans MIC 0.031 ug.mL-1 10.1016/j.bmcl.2009.02.036
Candida albicans Candida albicans MIC 0.031 ug.mL-1 10.1016/j.ejmech.2022.114161
Candida albicans Candida albicans MIC 0.031 ug.mL-1 10.1016/s0960-894x(02)00020-3
Candida albicans Candida albicans MIC 0.031 ug.mL-1 10.1021/jm800009r
Candida albicans Candida albicans MIC 0.031 ug.mL-1 10.1128/aac.00940-08
Candida albicans Candida albicans MIC 0.031 ug.mL-1 10.1128/aac.01070-07
Candida albicans Candida albicans MIC 0.031 ug.mL-1 10.1128/aac.01645-09
Candida albicans Candida albicans MIC 0.03125 ug.mL-1 10.1016/j.ejmech.2017.05.043
Candida albicans Candida albicans MIC 0.06 ug.mL-1 10.1016/j.bmcl.2015.10.028
Candida albicans Candida albicans MIC 0.06 ug.mL-1 10.1016/j.ejmech.2009.11.045
Candida albicans Candida albicans MIC 0.06 ug.mL-1 10.1016/j.ejmech.2015.04.047
Candida albicans Candida albicans MIC 0.06 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC 0.0625 ug.mL-1 10.1016/j.bmc.2016.11.051
Candida albicans Candida albicans MIC 0.0625 ug.mL-1 10.1016/j.bmcl.2019.07.037
Candida albicans Candida albicans MIC 0.0625 ug.mL-1 10.1016/j.ejmech.2010.07.002
Candida albicans Candida albicans MIC 0.0625 ug.mL-1 10.1016/j.ejmech.2019.03.020
Candida albicans Candida albicans MIC 0.0625 ug.mL-1 10.1128/aac.00303-10
Candida albicans Candida albicans MIC 0.0625 ug.mL-1 10.1128/aac.00348-10
Candida albicans Candida albicans MIC 0.063 ug.mL-1 10.1128/aac.01070-07
Candida albicans Candida albicans MIC 0.07 ug.mL-1 10.1021/jm00020a005
Candida albicans Candida albicans MIC 0.07 ug.mL-1 10.1128/aac.00231-10
Candida albicans Candida albicans MIC 0.096 ug.mL-1 10.1021/jm048997u
Candida albicans Candida albicans MIC 0.12 ug.mL-1 10.1016/0960-894X(96)00363-0
Candida albicans Candida albicans MIC 0.12 ug.mL-1 10.1016/j.ejmech.2009.09.024
Candida albicans Candida albicans MIC 0.12 ug.mL-1 10.1016/j.ejmech.2015.04.047
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1016/j.bmc.2018.04.054
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1016/j.bmcl.2008.10.055
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1016/j.bmcl.2009.02.036
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1016/j.bmcl.2011.06.062
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1016/j.ejmech.2010.10.019
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1016/j.ejmech.2016.07.067
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1016/j.ejmech.2017.05.043
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113715
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1016/s0960-894x(02)00020-3
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1128/aac.00940-08
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC 0.125 ug.mL-1 10.1128/aac.01645-09
Candida albicans Candida albicans MIC 0.23 ug.mL-1 10.1128/aac.00662-08
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1016/j.bmcl.2005.05.080
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1016/j.bmcl.2008.10.055
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1016/j.bmcl.2009.02.036
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1016/j.bmcl.2019.07.037
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1016/j.ejmech.2014.02.019
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1016/j.ejmech.2017.07.030
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1016/j.ejmech.2019.111689
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1016/j.ejmech.2022.114161
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1016/s0960-894x(02)00020-3
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1021/np1001412
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC 0.25 ug.mL-1 10.1128/aac.01645-09
Candida albicans Candida albicans MIC 0.32 ug.mL-1 10.1016/j.ejmech.2021.114060
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1016/j.bmc.2016.06.010
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1016/j.bmc.2018.04.054
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1016/j.bmcl.2008.04.056
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1016/j.bmcl.2013.01.039
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1016/j.bmcl.2014.08.047
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1016/j.ejmech.2016.07.067
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1016/j.ejmech.2021.114060
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.2c01497
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1021/jm800009r
Candida albicans Candida albicans MIC 0.5 ug.mL-1 10.1021/np1001412
Candida albicans Candida albicans MIC 0.6 ug.mL-1 10.1016/j.bmcl.2019.02.033
Candida albicans Candida albicans MIC 0.63 ug.mL-1 10.1021/jm00020a005
Candida albicans Candida albicans MIC 0.75 ug.mL-1 10.1039/C8MD00155C
Candida albicans Candida albicans MIC 1.0 ug.mL-1 10.1016/j.bmcl.2008.10.055
Candida albicans Candida albicans MIC 1.0 ug.mL-1 10.1016/j.bmcl.2009.02.036
Candida albicans Candida albicans MIC 1.0 ug.mL-1 10.1016/j.ejmech.2017.07.030
Candida albicans Candida albicans MIC 1.0 ug.mL-1 10.1016/s0960-894x(02)00020-3
Candida albicans Candida albicans MIC 1.56 ug.mL-1 10.1016/j.bmcl.2014.01.060
Candida albicans Candida albicans MIC 2.0 ug.mL-1 10.1039/C8MD00155C
Candida albicans Candida albicans MIC 2.0 ug.mL-1 10.1128/aac.00303-10
Candida albicans Candida albicans MIC 6.25 ug.mL-1 10.1007/s00044-010-9354-x
Candida albicans Candida albicans MIC 6.25 ug.mL-1 10.1021/acs.jmedchem.7b01348
Candida albicans Candida albicans MIC 7.8 ug.mL-1 10.1016/j.bmc.2016.06.010
Candida albicans Candida albicans MIC 8.0 ug.mL-1 10.1039/C8MD00155C
Candida albicans Candida albicans MIC 8.0 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC 16.0 ug.mL-1 10.1016/j.bmcl.2013.01.039
Candida albicans Candida albicans MIC 16.0 ug.mL-1 10.1021/acs.jmedchem.2c01497
Candida albicans Candida albicans MIC 16.0 ug.mL-1 10.1021/jm800009r
Candida albicans Candida albicans MIC 16.0 ug.mL-1 10.1039/C8MD00155C
Candida albicans Candida albicans MIC 16.0 ug.mL-1 10.1128/aac.00303-10
Candida albicans Candida albicans MIC 16.0 ug.mL-1 10.1128/aac.00348-10
Candida albicans Candida albicans MIC 16.0 ug.mL-1 10.1128/aac.00940-08
Candida albicans Candida albicans MIC 16.0 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC 16.0 ug.mL-1 10.1128/aac.01070-07
Candida albicans Candida albicans MIC 31.2 ug.mL-1 10.1016/j.bmc.2016.06.010
Candida albicans Candida albicans MIC 32.0 ug.mL-1 10.1016/j.ejmech.2017.07.030
Candida albicans Candida albicans MIC 32.0 ug.mL-1 10.1128/aac.00940-08
Candida albicans Candida albicans MIC 32.0 ug.mL-1 10.1128/aac.01070-07
Candida albicans Candida albicans MIC 62.5 ug.mL-1 10.1016/j.bmc.2016.06.010
Candida albicans Candida albicans MIC 64.0 ug.mL-1 10.1016/j.ejmech.2019.111689
Candida albicans Candida albicans MIC 64.0 ug.mL-1 10.1021/acs.jmedchem.2c01497
Candida albicans Candida albicans MIC 64.0 ug.mL-1 10.1039/C8MD00155C
Candida albicans Candida albicans MIC 64.0 ug.mL-1 10.1128/aac.00940-08
Candida albicans Candida albicans MIC 78.1 nM 10.6019/CHEMBL4513141
Candida albicans Candida albicans MIC 100.0 nM 10.1016/s0960-894x(00)00445-5
Candida albicans Candida albicans MIC 100.0 nM 10.1016/s0960-894x(00)00551-5
Candida albicans Candida albicans MIC 100.0 ug.mL-1 10.1016/j.ejmech.2020.112768
Candida albicans Candida albicans MIC 128.0 ug.mL-1 10.1128/aac.00940-08
Candida albicans Candida albicans MIC 128.0 ug.mL-1 10.1128/aac.01070-07
Candida albicans Candida albicans MIC 156.2 nM 10.6019/CHEMBL4513161
Candida albicans Candida albicans MIC 170.0 nM 10.1039/C0MD00074D
Candida albicans Candida albicans MIC 700.0 nM 10.1016/j.ejmech.2018.03.083
Candida albicans Candida albicans MIC 4420.0 nM 10.1039/C0MD00074D
Candida albicans Candida albicans MIC 10000.0 nM 10.1016/s0960-894x(00)00445-5
Candida albicans Candida albicans MIC 10000.0 nM 10.1016/s0960-894x(00)00551-5
Candida albicans Candida albicans MIC 20000.0 nM 10.1016/j.bmc.2014.03.044
Candida albicans Candida albicans MIC 64000.0 nM 10.1021/jm0701167
Candida albicans Candida albicans MIC 90700.0 nM 10.1016/j.ejmech.2011.10.053
Candida albicans Candida albicans MIC nan None 10.1016/j.bmcl.2013.03.078
Candida albicans Candida albicans MIC nan None 10.1016/j.ejmech.2020.112046
Candida albicans Candida albicans MIC50 0.0004 ug.mL-1 10.1128/aac.00926-08
Candida albicans Candida albicans MIC50 0.0063 ug.mL-1 10.1128/aac.00926-08
Candida albicans Candida albicans MIC50 0.008 ug.mL-1 10.1128/aac.01217-06
Candida albicans Candida albicans MIC50 0.0125 ug.mL-1 10.1128/aac.00926-08
Candida albicans Candida albicans MIC50 0.015 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC50 0.016 ug.mL-1 10.1016/j.bmcl.2014.05.068
Candida albicans Candida albicans MIC50 0.02 ug.mL-1 10.1128/aac.01543-08
Candida albicans Candida albicans MIC50 0.025 ug.mL-1 10.1128/aac.00926-08
Candida albicans Candida albicans MIC50 0.03 ug.mL-1 10.1128/aac.00323-08
Candida albicans Candida albicans MIC50 0.03 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC50 0.03 ug.mL-1 10.1128/aac.01413-08
Candida albicans Candida albicans MIC50 0.04 ug.mL-1 10.1128/aac.00231-10
Candida albicans Candida albicans MIC50 0.058 ug.mL-1 10.1128/aac.00118-10
Candida albicans Candida albicans MIC50 0.06 ug.mL-1 10.1128/aac.00459-07
Candida albicans Candida albicans MIC50 0.062 ug.mL-1 10.1021/jm048997u
Candida albicans Candida albicans MIC50 0.074 ug.mL-1 10.1128/aac.00118-10
Candida albicans Candida albicans MIC50 0.107 ug.mL-1 10.1128/aac.00118-10
Candida albicans Candida albicans MIC50 0.111 ug.mL-1 10.1128/aac.00118-10
Candida albicans Candida albicans MIC50 0.12 ug.mL-1 10.1128/aac.00459-07
Candida albicans Candida albicans MIC50 0.12 ug.mL-1 10.1128/aac.01475-07
Candida albicans Candida albicans MIC50 0.2 ug.mL-1 10.1128/aac.00926-08
Candida albicans Candida albicans MIC50 0.255 ug.mL-1 10.1128/aac.00118-10
Candida albicans Candida albicans MIC50 0.297 ug.mL-1 10.1128/aac.00118-10
Candida albicans Candida albicans MIC50 0.5 ug.mL-1 10.1021/acs.jmedchem.5b01375
Candida albicans Candida albicans MIC50 0.5 ug.mL-1 10.1021/jm800009r
Candida albicans Candida albicans MIC50 0.75 ug.mL-1 10.1128/aac.00459-07
Candida albicans Candida albicans MIC50 7.8 ug.mL-1 10.1021/acs.jmedchem.5b01375
Candida albicans Candida albicans MIC50 16.0 ug.mL-1 10.1016/j.ejmech.2021.113955
Candida albicans Candida albicans MIC50 31.2 ug.mL-1 10.1021/acs.jmedchem.5b01375
Candida albicans Candida albicans MIC50 32.0 ug.mL-1 10.1016/j.ejmech.2021.113955
Candida albicans Candida albicans MIC50 62.5 ug.mL-1 10.1021/acs.jmedchem.5b01375
Candida albicans Candida albicans MIC50 64.0 ug.mL-1 10.1016/j.ejmech.2021.113955
Candida albicans Candida albicans MIC50 710.0 nM 10.1016/j.ejmech.2017.03.075
Candida albicans Candida albicans MIC50 11100.0 nM 10.1016/j.ejmech.2017.03.075
Candida albicans Candida albicans MIC50 44400.0 nM 10.1016/j.ejmech.2017.03.075
Candida albicans Candida albicans MIC50 88600.0 nM 10.1016/j.ejmech.2017.03.075
Candida albicans Candida albicans MIC80 0.016 ug.mL-1 10.1016/j.bmcl.2010.03.014
Candida albicans Candida albicans MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2009.01.048
Candida albicans Candida albicans MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2011.06.008
Candida albicans Candida albicans MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2012.02.042
Candida albicans Candida albicans MIC80 0.0625 ug.mL-1 10.1016/j.ejmech.2008.11.007
Candida albicans Candida albicans MIC80 0.0625 ug.mL-1 10.1016/j.ejmech.2011.02.001
Candida albicans Candida albicans MIC80 0.0625 ug.mL-1 10.1039/C3MD20086H
Candida albicans Candida albicans MIC80 0.125 ug.mL-1 10.1016/j.bmc.2021.116188
Candida albicans Candida albicans MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2009.07.144
Candida albicans Candida albicans MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2009.05.018
Candida albicans Candida albicans MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2012.04.013
Candida albicans Candida albicans MIC80 0.125 ug.mL-1 10.1021/jm051211n
Candida albicans Candida albicans MIC80 0.25 ug.mL-1 10.1016/j.bmcl.2013.11.037
Candida albicans Candida albicans MIC80 0.5 ug.mL-1 10.1016/j.ejmech.2021.113524
Candida albicans Candida albicans MIC80 0.5 ug.mL-1 10.1021/acs.jmedchem.0c00102
Candida albicans Candida albicans MIC80 1.0 ug.mL-1 10.1016/j.bmcl.2010.12.006
Candida albicans Candida albicans MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2007.01.006
Candida albicans Candida albicans MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2011.02.042
Candida albicans Candida albicans MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2011.04.022
Candida albicans Candida albicans MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2014.05.079
Candida albicans Candida albicans MIC80 4.0 ug.mL-1 10.1016/j.ejmech.2014.01.009
Candida albicans Candida albicans MIC80 4.0 ug.mL-1 10.1021/np500024r
Candida albicans Candida albicans MIC80 8.0 ug.mL-1 10.1016/j.ejmech.2014.01.009
Candida albicans Candida albicans MIC80 8.0 ug.mL-1 10.1016/j.ejmech.2017.10.043
Candida albicans Candida albicans MIC80 64.0 ug.mL-1 10.1016/j.ejmech.2009.05.018
Candida albicans Candida albicans MIC80 64.0 ug.mL-1 10.1016/j.ejmech.2021.113524
Candida albicans Candida albicans MIC80 64.0 ug.mL-1 10.1021/acs.jmedchem.0c00102
Candida albicans Candida albicans MIC80 nan None 10.1016/j.ejmech.2021.113524
Candida albicans Candida albicans MIC90 0.015 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC90 0.016 ug.mL-1 10.1128/aac.01217-06
Candida albicans Candida albicans MIC90 0.03 ug.mL-1 10.1128/aac.00323-08
Candida albicans Candida albicans MIC90 0.03 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC90 0.03 ug.mL-1 10.1128/aac.01543-08
Candida albicans Candida albicans MIC90 0.06 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC90 0.09 ug.mL-1 10.1128/aac.00231-10
Candida albicans Candida albicans MIC90 0.12 ug.mL-1 10.1016/j.ejmech.2013.10.051
Candida albicans Candida albicans MIC90 0.125 ug.mL-1 10.1021/jm048997u
Candida albicans Candida albicans MIC90 0.25 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC90 0.5 ug.mL-1 10.1128/aac.01368-08
Candida albicans Candida albicans MIC90 1.0 ug.mL-1 10.1021/jm800009r
Candida albicans Candida albicans MIC90 16.0 ug.mL-1 10.1128/aac.01031-09
Candida albicans Candida albicans MIC90 16.0 ug.mL-1 10.1128/aac.01475-07
Candida albicans Candida albicans MIC90 256.0 ug.mL-1 10.1016/j.ejmech.2013.10.051
Candida albicans Candida albicans Protection 0.0 % 10.1021/jm970726e
Candida albicans Candida albicans Protection 0.0 % 10.1021/jm9707277
Candida albicans Candida albicans Ratio 1.0 None 10.1128/aac.00926-08
Candida albicans Candida albicans Ratio 2.0 None 10.1016/j.ejmech.2017.11.089
Candida albicans Candida albicans Ratio 8.0 None 10.1128/aac.00926-08
Candida albicans Candida albicans Ratio 500.0 None 10.1128/aac.00926-08
[Candida] auris [Candida] auris MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.2c01497
[Candida] auris [Candida] auris MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.2c01497
[Candida] auris [Candida] auris MIC nan None 10.1016/j.ejmech.2020.112046
Candida dubliniensis Candida dubliniensis IZ 19.45 mm 10.1039/C0MD00074D
Candida dubliniensis Candida dubliniensis MFC 256.0 ug ml-1 10.1016/j.ejmech.2013.10.051
Candida dubliniensis Candida dubliniensis MIC 0.028 ug.mL-1 10.1128/aac.00231-10
Candida dubliniensis Candida dubliniensis MIC 0.06 ug.mL-1 10.1016/j.ejmech.2019.07.003
Candida dubliniensis Candida dubliniensis MIC 0.06 ug.mL-1 10.1128/aac.01368-08
Candida dubliniensis Candida dubliniensis MIC 20.0 nM 10.1039/C0MD00074D
Candida dubliniensis Candida dubliniensis MIC50 0.03 ug.mL-1 10.1128/aac.00231-10
Candida dubliniensis Candida dubliniensis MIC90 0.06 ug.mL-1 10.1128/aac.00231-10
Candida dubliniensis Candida dubliniensis MIC90 256.0 ug.mL-1 10.1016/j.ejmech.2013.10.051
[Candida] inconspicua [Candida] inconspicua MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
[Candida] inconspicua [Candida] inconspicua MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
[Candida] intermedia [Candida] intermedia MIC 0.12 ug.mL-1 10.1128/aac.01368-08
[Candida] intermedia [Candida] intermedia MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
[Candida] intermedia [Candida] intermedia MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Candida metapsilosis Candida metapsilosis MIC 4e-05 ug.mL-1 10.1128/aac.01595-07
Candida metapsilosis Candida metapsilosis MIC50 4e-05 ug.mL-1 10.1128/aac.01595-07
Candida metapsilosis Candida metapsilosis MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
Candida metapsilosis Candida metapsilosis MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Candida orthopsilosis Candida orthopsilosis MIC 4e-05 ug.mL-1 10.1128/aac.01595-07
Candida orthopsilosis Candida orthopsilosis MIC50 3e-05 ug.mL-1 10.1128/aac.01595-07
Candida orthopsilosis Candida orthopsilosis MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
Candida orthopsilosis Candida orthopsilosis MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Candida parapsilosis Candida parapsilosis Activity 0.0 % 10.1128/aac.00323-08
Candida parapsilosis Candida parapsilosis Activity 0.0 % 10.1128/aac.01475-07
Candida parapsilosis Candida parapsilosis Activity 22.0 % 10.1128/aac.00323-08
Candida parapsilosis Candida parapsilosis Activity 63.6 % 10.1128/aac.01475-07
Candida parapsilosis Candida parapsilosis Activity 78.0 % 10.1128/aac.00323-08
Candida parapsilosis Candida parapsilosis Activity nan None 10.1016/j.ejmech.2009.05.018
Candida parapsilosis Candida parapsilosis Activity nan None 10.1016/j.ejmech.2013.06.018
Candida parapsilosis Candida parapsilosis IZ 26.01 mm 10.1039/C0MD00074D
Candida parapsilosis Candida parapsilosis MFC 0.06 ug ml-1 10.1128/aac.00662-08
Candida parapsilosis Candida parapsilosis MFC 0.25 ug ml-1 10.1021/jm800009r
Candida parapsilosis Candida parapsilosis MFC 0.5 ug ml-1 10.1016/j.ejmech.2013.10.051
Candida parapsilosis Candida parapsilosis MIC 2e-05 ug.mL-1 10.1128/aac.01595-07
Candida parapsilosis Candida parapsilosis MIC 0.007 ug.mL-1 10.1016/j.ejmech.2019.03.023
Candida parapsilosis Candida parapsilosis MIC 0.007 ug.mL-1 10.1016/j.ejmech.2019.07.003
Candida parapsilosis Candida parapsilosis MIC 0.015 ug.mL-1 10.1039/C8MD00155C
Candida parapsilosis Candida parapsilosis MIC 0.015 ug.mL-1 10.1128/aac.01475-07
Candida parapsilosis Candida parapsilosis MIC 0.03 ug.mL-1 10.1016/j.bmcl.2013.01.039
Candida parapsilosis Candida parapsilosis MIC 0.03 ug.mL-1 10.1016/j.ejmech.2019.07.003
Candida parapsilosis Candida parapsilosis MIC 0.03 ug.mL-1 10.1128/aac.00323-08
Candida parapsilosis Candida parapsilosis MIC 0.03 ug.mL-1 10.1128/aac.01016-07
Candida parapsilosis Candida parapsilosis MIC 0.03 ug.mL-1 10.1128/aac.01368-08
Candida parapsilosis Candida parapsilosis MIC 0.0312 ug.mL-1 10.1016/j.bmcl.2008.04.056
Candida parapsilosis Candida parapsilosis MIC 0.04 ug.mL-1 10.1016/j.bmcl.2014.01.060
Candida parapsilosis Candida parapsilosis MIC 0.06 ug.mL-1 10.1016/j.ejmech.2009.09.024
Candida parapsilosis Candida parapsilosis MIC 0.06 ug.mL-1 10.1021/jm800009r
Candida parapsilosis Candida parapsilosis MIC 0.06 ug.mL-1 10.1039/C7MD00442G
Candida parapsilosis Candida parapsilosis MIC 0.0625 ug.mL-1 10.1016/j.bmc.2012.04.045
Candida parapsilosis Candida parapsilosis MIC 0.0625 ug.mL-1 10.1016/j.ejmech.2010.07.002
Candida parapsilosis Candida parapsilosis MIC 0.07 ug.mL-1 10.1021/jm00020a005
Candida parapsilosis Candida parapsilosis MIC 0.07 ug.mL-1 10.1128/aac.00231-10
Candida parapsilosis Candida parapsilosis MIC 0.12 ug.mL-1 10.1016/j.bmc.2016.06.010
Candida parapsilosis Candida parapsilosis MIC 0.12 ug.mL-1 10.1128/aac.01016-07
Candida parapsilosis Candida parapsilosis MIC 0.125 ug.mL-1 10.1016/j.bmcl.2008.10.055
Candida parapsilosis Candida parapsilosis MIC 0.125 ug.mL-1 10.1016/j.bmcl.2009.02.036
Candida parapsilosis Candida parapsilosis MIC 0.125 ug.mL-1 10.1016/j.ejmech.2010.10.019
Candida parapsilosis Candida parapsilosis MIC 0.125 ug.mL-1 10.1016/j.ejmech.2019.111689
Candida parapsilosis Candida parapsilosis MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113715
Candida parapsilosis Candida parapsilosis MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113740
Candida parapsilosis Candida parapsilosis MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113955
Candida parapsilosis Candida parapsilosis MIC 0.125 ug.mL-1 10.1016/j.ejmech.2022.114195
Candida parapsilosis Candida parapsilosis MIC 0.125 ug.mL-1 10.1128/aac.01176-06
Candida parapsilosis Candida parapsilosis MIC 0.25 ug.mL-1 10.1016/j.bmcl.2005.05.080
Candida parapsilosis Candida parapsilosis MIC 0.25 ug.mL-1 10.1016/j.bmcl.2011.06.062
Candida parapsilosis Candida parapsilosis MIC 0.25 ug.mL-1 10.1016/j.ejmech.2015.04.047
Candida parapsilosis Candida parapsilosis MIC 0.25 ug.mL-1 10.1016/j.ejmech.2022.114161
Candida parapsilosis Candida parapsilosis MIC 0.25 ug.mL-1 10.1021/np1001412
Candida parapsilosis Candida parapsilosis MIC 0.25 ug.mL-1 10.1128/aac.01176-06
Candida parapsilosis Candida parapsilosis MIC 0.32 ug.mL-1 10.1128/aac.00662-08
Candida parapsilosis Candida parapsilosis MIC 0.5 ug.mL-1 10.1016/j.bmcl.2013.01.039
Candida parapsilosis Candida parapsilosis MIC 0.5 ug.mL-1 10.1021/acs.jmedchem.2c01497
Candida parapsilosis Candida parapsilosis MIC 0.5 ug.mL-1 10.1039/C8MD00155C
Candida parapsilosis Candida parapsilosis MIC 0.5 ug.mL-1 10.1128/aac.01176-06
Candida parapsilosis Candida parapsilosis MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.2c01497
Candida parapsilosis Candida parapsilosis MIC 4.0 ug.mL-1 10.1021/acs.jmedchem.2c01497
Candida parapsilosis Candida parapsilosis MIC 16.0 ug.mL-1 10.1021/np1001412
Candida parapsilosis Candida parapsilosis MIC 20.0 nM 10.1039/C0MD00074D
Candida parapsilosis Candida parapsilosis MIC 100.0 nM 10.1016/s0960-894x(00)00445-5
Candida parapsilosis Candida parapsilosis MIC 100.0 nM 10.1016/s0960-894x(00)00551-5
Candida parapsilosis Candida parapsilosis MIC 180.0 nM 10.1016/j.ejmech.2018.03.083
Candida parapsilosis Candida parapsilosis MIC 512.0 ug.mL-1 10.1016/j.bmcl.2013.03.078
Candida parapsilosis Candida parapsilosis MIC 512.0 ug.mL-1 10.1016/j.bmcl.2014.08.047
Candida parapsilosis Candida parapsilosis MIC 710.0 nM 10.1016/j.bmcl.2014.01.022
Candida parapsilosis Candida parapsilosis MIC nan None 10.1016/j.ejmech.2020.112046
Candida parapsilosis Candida parapsilosis MIC50 3e-05 ug.mL-1 10.1128/aac.01595-07
Candida parapsilosis Candida parapsilosis MIC50 0.016 ug.mL-1 10.1128/aac.01217-06
Candida parapsilosis Candida parapsilosis MIC50 0.02 ug.mL-1 10.1128/aac.01543-08
Candida parapsilosis Candida parapsilosis MIC50 0.06 ug.mL-1 10.1128/aac.00231-10
Candida parapsilosis Candida parapsilosis MIC50 0.06 ug.mL-1 10.1128/aac.00323-08
Candida parapsilosis Candida parapsilosis MIC50 0.06 ug.mL-1 10.1128/aac.01413-08
Candida parapsilosis Candida parapsilosis MIC50 0.06 ug.mL-1 10.1128/aac.01475-07
Candida parapsilosis Candida parapsilosis MIC50 0.25 ug.mL-1 10.1128/aac.00459-07
Candida parapsilosis Candida parapsilosis MIC50 170.0 nM 10.1016/j.ejmech.2017.03.075
Candida parapsilosis Candida parapsilosis MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2010.03.014
Candida parapsilosis Candida parapsilosis MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2011.06.008
Candida parapsilosis Candida parapsilosis MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2012.02.042
Candida parapsilosis Candida parapsilosis MIC80 0.0625 ug.mL-1 10.1016/j.ejmech.2011.02.001
Candida parapsilosis Candida parapsilosis MIC80 0.0625 ug.mL-1 10.1039/C3MD20086H
Candida parapsilosis Candida parapsilosis MIC80 0.125 ug.mL-1 10.1016/j.bmc.2021.116188
Candida parapsilosis Candida parapsilosis MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2009.01.048
Candida parapsilosis Candida parapsilosis MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2013.11.037
Candida parapsilosis Candida parapsilosis MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2008.11.007
Candida parapsilosis Candida parapsilosis MIC80 0.25 ug.mL-1 10.1016/j.bmcl.2010.12.006
Candida parapsilosis Candida parapsilosis MIC80 0.25 ug.mL-1 10.1016/j.ejmech.2007.01.006
Candida parapsilosis Candida parapsilosis MIC80 0.25 ug.mL-1 10.1016/j.ejmech.2011.02.042
Candida parapsilosis Candida parapsilosis MIC80 0.25 ug.mL-1 10.1016/j.ejmech.2011.04.022
Candida parapsilosis Candida parapsilosis MIC80 0.25 ug.mL-1 10.1021/jm051211n
Candida parapsilosis Candida parapsilosis MIC80 4.0 ug.mL-1 10.1016/j.ejmech.2012.04.013
Candida parapsilosis Candida parapsilosis MIC80 4.0 ug.mL-1 10.1016/j.ejmech.2014.05.079
Candida parapsilosis Candida parapsilosis MIC80 8.0 ug.mL-1 10.1016/j.ejmech.2014.01.009
Candida parapsilosis Candida parapsilosis MIC80 8.0 ug.mL-1 10.1016/j.ejmech.2017.10.043
Candida parapsilosis Candida parapsilosis MIC80 8.0 ug.mL-1 10.1021/np500024r
Candida parapsilosis Candida parapsilosis MIC90 0.03 ug.mL-1 10.1128/aac.01543-08
Candida parapsilosis Candida parapsilosis MIC90 0.063 ug.mL-1 10.1128/aac.01217-06
Candida parapsilosis Candida parapsilosis MIC90 0.12 ug.mL-1 10.1128/aac.01368-08
Candida parapsilosis Candida parapsilosis MIC90 0.125 ug.mL-1 10.1128/aac.00231-10
Candida parapsilosis Candida parapsilosis MIC90 0.25 ug.mL-1 10.1016/j.ejmech.2013.06.018
Candida parapsilosis Candida parapsilosis MIC90 0.25 ug.mL-1 10.1016/j.ejmech.2013.10.051
Candida parapsilosis Candida parapsilosis MIC90 0.25 ug.mL-1 10.1128/aac.00323-08
Candida parapsilosis Candida parapsilosis MIC90 0.25 ug.mL-1 10.1128/aac.01475-07
Candida parapsilosis Candida parapsilosis MIC90 0.6 ug.mL-1 10.1016/j.ejmech.2013.10.051
Candida tropicalis Candida tropicalis Activity 0.0 % 10.1128/aac.00323-08
Candida tropicalis Candida tropicalis Activity 0.0 % 10.1128/aac.01475-07
Candida tropicalis Candida tropicalis Activity 35.0 % 10.1128/aac.00323-08
Candida tropicalis Candida tropicalis Activity 65.0 % 10.1128/aac.00323-08
Candida tropicalis Candida tropicalis Activity 100.0 % 10.1128/aac.01475-07
Candida tropicalis Candida tropicalis IZ 23.63 mm 10.1039/C0MD00074D
Candida tropicalis Candida tropicalis MFC 0.25 ug ml-1 10.1128/aac.00662-08
Candida tropicalis Candida tropicalis MFC 256.0 ug ml-1 10.1016/j.ejmech.2013.10.051
Candida tropicalis Candida tropicalis MIC 0.007 ug.mL-1 10.1016/j.ejmech.2019.03.023
Candida tropicalis Candida tropicalis MIC 0.015 ug.mL-1 10.1128/aac.01031-09
Candida tropicalis Candida tropicalis MIC 0.015 ug.mL-1 10.1128/aac.01475-07
Candida tropicalis Candida tropicalis MIC 0.03 ug.mL-1 10.1016/j.ejmech.2016.02.013
Candida tropicalis Candida tropicalis MIC 0.03 ug.mL-1 10.1016/j.ejmech.2019.05.047
Candida tropicalis Candida tropicalis MIC 0.03 ug.mL-1 10.1016/j.ejmech.2019.111689
Candida tropicalis Candida tropicalis MIC 0.03 ug.mL-1 10.1016/j.ejmech.2021.113740
Candida tropicalis Candida tropicalis MIC 0.03 ug.mL-1 10.1016/j.ejmech.2021.113955
Candida tropicalis Candida tropicalis MIC 0.03 ug.mL-1 10.1016/j.ejmech.2021.113987
Candida tropicalis Candida tropicalis MIC 0.03 ug.mL-1 10.1016/j.ejmech.2022.114195
Candida tropicalis Candida tropicalis MIC 0.03 ug.mL-1 10.1128/aac.00323-08
Candida tropicalis Candida tropicalis MIC 0.03 ug.mL-1 10.1128/aac.01031-09
Candida tropicalis Candida tropicalis MIC 0.03125 ug.mL-1 10.1016/j.ejmech.2017.05.043
Candida tropicalis Candida tropicalis MIC 0.06 ug.mL-1 10.1016/j.ejmech.2009.11.045
Candida tropicalis Candida tropicalis MIC 0.06 ug.mL-1 10.1016/j.ejmech.2015.04.047
Candida tropicalis Candida tropicalis MIC 0.06 ug.mL-1 10.1039/C7MD00442G
Candida tropicalis Candida tropicalis MIC 0.0625 ug.mL-1 10.1016/j.bmc.2012.04.045
Candida tropicalis Candida tropicalis MIC 0.0625 ug.mL-1 10.1016/j.ejmech.2010.07.002
Candida tropicalis Candida tropicalis MIC 0.0625 ug.mL-1 10.1016/j.ejmech.2019.03.020
Candida tropicalis Candida tropicalis MIC 0.11 ug.mL-1 10.1128/aac.00231-10
Candida tropicalis Candida tropicalis MIC 0.12 ug.mL-1 10.1016/j.bmcl.2005.05.080
Candida tropicalis Candida tropicalis MIC 0.12 ug.mL-1 10.1128/aac.01368-08
Candida tropicalis Candida tropicalis MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113715
Candida tropicalis Candida tropicalis MIC 0.125 ug.mL-1 10.1128/aac.00802-08
Candida tropicalis Candida tropicalis MIC 0.19 ug.mL-1 10.1016/j.bmcl.2014.01.060
Candida tropicalis Candida tropicalis MIC 0.25 ug.mL-1 10.1016/j.bmcl.2008.04.056
Candida tropicalis Candida tropicalis MIC 0.25 ug.mL-1 10.1016/j.ejmech.2022.114161
Candida tropicalis Candida tropicalis MIC 0.25 ug.mL-1 10.1128/aac.00802-08
Candida tropicalis Candida tropicalis MIC 0.5 ug.mL-1 10.1016/j.bmc.2018.04.054
Candida tropicalis Candida tropicalis MIC 0.5 ug.mL-1 10.1016/j.bmcl.2008.10.055
Candida tropicalis Candida tropicalis MIC 0.5 ug.mL-1 10.1016/j.bmcl.2009.02.036
Candida tropicalis Candida tropicalis MIC 0.5 ug.mL-1 10.1016/j.bmcl.2019.07.037
Candida tropicalis Candida tropicalis MIC 0.5 ug.mL-1 10.1016/j.ejmech.2016.07.067
Candida tropicalis Candida tropicalis MIC 0.5 ug.mL-1 10.1016/s0960-894x(02)00020-3
Candida tropicalis Candida tropicalis MIC 0.5 ug.mL-1 10.1128/aac.00802-08
Candida tropicalis Candida tropicalis MIC 0.56 ug.mL-1 10.1128/aac.00662-08
Candida tropicalis Candida tropicalis MIC 1.0 ug.mL-1 10.1128/aac.00802-08
Candida tropicalis Candida tropicalis MIC 16.0 ug.mL-1 10.1021/acs.jmedchem.2c01497
Candida tropicalis Candida tropicalis MIC 20.0 ug.mL-1 10.1021/jm00020a005
Candida tropicalis Candida tropicalis MIC 25.0 ug.mL-1 10.1039/C8MD00155C
Candida tropicalis Candida tropicalis MIC 90.0 nM 10.1016/j.ejmech.2018.03.083
Candida tropicalis Candida tropicalis MIC 100.0 nM 10.1016/s0960-894x(00)00445-5
Candida tropicalis Candida tropicalis MIC 100.0 nM 10.1016/s0960-894x(00)00551-5
Candida tropicalis Candida tropicalis MIC 170.0 nM 10.1039/C0MD00074D
Candida tropicalis Candida tropicalis MIC 512.0 ug.mL-1 10.1016/j.bmcl.2013.03.078
Candida tropicalis Candida tropicalis MIC 512.0 ug.mL-1 10.1016/j.bmcl.2014.08.047
Candida tropicalis Candida tropicalis MIC50 0.02 ug.mL-1 10.1128/aac.01543-08
Candida tropicalis Candida tropicalis MIC50 0.03 ug.mL-1 10.1128/aac.01475-07
Candida tropicalis Candida tropicalis MIC50 0.12 ug.mL-1 10.1128/aac.00323-08
Candida tropicalis Candida tropicalis MIC50 0.125 ug.mL-1 10.1128/aac.00231-10
Candida tropicalis Candida tropicalis MIC80 0.0156 ug.mL-1 10.1016/j.bmcl.2009.07.144
Candida tropicalis Candida tropicalis MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2010.03.014
Candida tropicalis Candida tropicalis MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2011.06.008
Candida tropicalis Candida tropicalis MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2012.02.042
Candida tropicalis Candida tropicalis MIC80 0.0625 ug.mL-1 10.1016/j.ejmech.2011.02.001
Candida tropicalis Candida tropicalis MIC80 0.0625 ug.mL-1 10.1039/C3MD20086H
Candida tropicalis Candida tropicalis MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2009.01.048
Candida tropicalis Candida tropicalis MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2008.11.007
Candida tropicalis Candida tropicalis MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2009.05.018
Candida tropicalis Candida tropicalis MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2012.04.013
Candida tropicalis Candida tropicalis MIC80 0.125 ug.mL-1 10.1021/jm051211n
Candida tropicalis Candida tropicalis MIC80 0.25 ug.mL-1 10.1016/j.bmcl.2010.12.006
Candida tropicalis Candida tropicalis MIC80 0.25 ug.mL-1 10.1016/j.ejmech.2007.01.006
Candida tropicalis Candida tropicalis MIC80 0.25 ug.mL-1 10.1016/j.ejmech.2011.02.042
Candida tropicalis Candida tropicalis MIC80 0.25 ug.mL-1 10.1016/j.ejmech.2011.04.022
Candida tropicalis Candida tropicalis MIC80 1.0 ug.mL-1 10.1016/j.bmc.2021.116188
Candida tropicalis Candida tropicalis MIC80 64.0 ug.mL-1 10.1016/j.ejmech.2021.113524
Candida tropicalis Candida tropicalis MIC80 64.0 ug.mL-1 10.1021/acs.jmedchem.0c00102
Candida tropicalis Candida tropicalis MIC90 0.06 ug.mL-1 10.1128/aac.01543-08
Candida tropicalis Candida tropicalis MIC90 0.12 ug.mL-1 10.1128/aac.01368-08
Candida tropicalis Candida tropicalis MIC90 0.12 ug.mL-1 10.1128/aac.01475-07
Candida tropicalis Candida tropicalis MIC90 0.25 ug.mL-1 10.1128/aac.00231-10
Candida tropicalis Candida tropicalis MIC90 0.25 ug.mL-1 10.1128/aac.00323-08
Candida tropicalis Candida tropicalis MIC90 1.0 ug.mL-1 10.1016/j.ejmech.2013.10.051
Candida tropicalis Candida tropicalis MIC90 256.0 ug.mL-1 10.1016/j.ejmech.2013.10.051
[Candida] zeylanoides [Candida] zeylanoides MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
[Candida] zeylanoides [Candida] zeylanoides MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Cavia porcellus Cavia porcellus ED50 0.84 mg.kg-1 10.1021/jm0494772
Cavia porcellus Cavia porcellus ED50 1.18 mg.kg-1 10.1021/jm0494772
Cavia porcellus Cavia porcellus ED50 1.2 mg.kg-1 10.1021/jm0494772
Cavia porcellus Cavia porcellus T1/2 13.9 hr 10.1128/aac.00730-10
Cavia porcellus Cavia porcellus Tmax 2.0 hr 10.1128/aac.00730-10
Cavia porcellus Leukotriene C4 synthase IC50 nan None None
Cavia porcellus Leukotriene C4 synthase Ki nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor IC50 nan None None
Cavia porcellus Serotonin 4 (5-HT4) receptor Ki nan None None
Chikungunya virus Chikungunya virus EC50 320.0 nM 10.1016/j.bmc.2023.117239
Chlorocebus sabaeus Vero IC50 50.0 ug.mL-1 10.1016/j.ejmech.2013.06.018
Chlorocebus sabaeus Vero C1008 CC50 100000.0 nM 10.6019/CHEMBL4651402
Chlorocebus sabaeus Vero C1008 pCC50 4.0 None 10.6019/CHEMBL4651402
Cladosporium Cladosporium MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
Cladosporium Cladosporium MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Clavispora lusitaniae Clavispora lusitaniae Activity 0.0 % 10.1128/aac.00323-08
Clavispora lusitaniae Clavispora lusitaniae Activity 100.0 % 10.1128/aac.00323-08
Clavispora lusitaniae Clavispora lusitaniae MFC 0.25 ug ml-1 10.1128/aac.00662-08
Clavispora lusitaniae Clavispora lusitaniae MIC 0.03 ug.mL-1 10.1128/aac.00323-08
Clavispora lusitaniae Clavispora lusitaniae MIC 0.07 ug.mL-1 10.1128/aac.00662-08
Clavispora lusitaniae Clavispora lusitaniae MIC 0.09 ug.mL-1 10.1128/aac.00231-10
Clavispora lusitaniae Clavispora lusitaniae MIC 0.12 ug.mL-1 10.1128/aac.01368-08
Clavispora lusitaniae Clavispora lusitaniae MIC 0.125 ug.mL-1 10.1016/j.ejmech.2009.11.045
Clavispora lusitaniae Clavispora lusitaniae MIC 0.2 ug.mL-1 10.1039/C8MD00155C
Clavispora lusitaniae Clavispora lusitaniae MIC50 0.02 ug.mL-1 10.1128/aac.01543-08
Clavispora lusitaniae Clavispora lusitaniae MIC50 0.06 ug.mL-1 10.1128/aac.00231-10
Clavispora lusitaniae Clavispora lusitaniae MIC50 0.06 ug.mL-1 10.1128/aac.00323-08
Clavispora lusitaniae Clavispora lusitaniae MIC90 0.03 ug.mL-1 10.1128/aac.01543-08
Clavispora lusitaniae Clavispora lusitaniae MIC90 0.06 ug.mL-1 10.1128/aac.00323-08
Clavispora lusitaniae Clavispora lusitaniae MIC90 0.25 ug.mL-1 10.1128/aac.00231-10
Clavispora lusitaniae Clavispora lusitaniae MIC90 0.25 ug.mL-1 10.1128/aac.01368-08
Coccidioides immitis Coccidioides immitis Activity nan None 10.1128/aac.00332-06
Coccidioides immitis Coccidioides immitis log10CFU/g 0.75 None 10.1128/aac.00332-06
Coccidioides immitis Coccidioides immitis log10CFU/g 1.73 None 10.1128/aac.00332-06
Colletotrichum falcatum Colletotrichum falcatum IZ 4.45 mm 10.1007/s00044-013-0543-2
Colletotrichum falcatum Colletotrichum falcatum IZ 4.67 mm 10.1007/s00044-013-0573-9
Colletotrichum falcatum Colletotrichum falcatum IZ 9.34 mm 10.1007/s00044-013-0543-2
Colletotrichum falcatum Colletotrichum falcatum IZ 9.34 mm 10.1007/s00044-013-0573-9
Colletotrichum falcatum Colletotrichum falcatum IZ 18.26 mm 10.1007/s00044-013-0543-2
Colletotrichum falcatum Colletotrichum falcatum IZ 18.26 mm 10.1007/s00044-013-0573-9
Colletotrichum falcatum Colletotrichum falcatum IZ 33.35 mm 10.1007/s00044-013-0573-9
Colletotrichum falcatum Colletotrichum falcatum IZ 33.75 mm 10.1007/s00044-013-0543-2
Colletotrichum graminicola Colletotrichum graminicola ED50 0.007 ug ml-1 10.1128/aac.00654-07
Colletotrichum graminicola Colletotrichum graminicola ED50 0.014 ug ml-1 10.1128/aac.00654-07
Colletotrichum graminicola Colletotrichum graminicola ED90 1.351 ug ml-1 10.1128/aac.00654-07
Colletotrichum graminicola Colletotrichum graminicola ED90 8.848 ug ml-1 10.1128/aac.00654-07
Cryptococcus gattii Cryptococcus bacillisporus MFC 0.5 ug ml-1 10.1128/aac.00662-08
Cryptococcus gattii Cryptococcus bacillisporus MIC 0.016 ug.mL-1 10.1128/aac.01384-07
Cryptococcus gattii Cryptococcus bacillisporus MIC 0.07 ug.mL-1 10.1128/aac.00231-10
Cryptococcus gattii Cryptococcus bacillisporus MIC 0.22 ug.mL-1 10.1128/aac.00662-08
Cryptococcus gattii Cryptococcus bacillisporus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2014.02.019
Cryptococcus gattii Cryptococcus bacillisporus MIC 16.0 ug.mL-1 10.1021/np1001412
Cryptococcus gattii Cryptococcus bacillisporus MIC 180.0 nM 10.1016/j.ejmech.2018.03.083
Cryptococcus gattii Cryptococcus bacillisporus MIC nan None 10.1016/j.ejmech.2020.112046
Cryptococcus gattii Cryptococcus bacillisporus MIC50 0.03 ug.mL-1 10.1007/s00044-009-9170-3
Cryptococcus gattii Cryptococcus bacillisporus MIC50 0.06 ug.mL-1 10.1128/aac.00231-10
Cryptococcus gattii Cryptococcus bacillisporus MIC50 0.063 ug.mL-1 10.1128/aac.01384-07
Cryptococcus gattii Cryptococcus bacillisporus MIC90 0.125 ug.mL-1 10.1128/aac.00231-10
Cryptococcus gattii Cryptococcus bacillisporus MIC90 0.25 ug.mL-1 10.1128/aac.01384-07
Cryptococcus neoformans Cryptococcus neoformans IC80 0.022 ug ml-1 10.1016/S0960-894X(01)80190-6
Cryptococcus neoformans Cryptococcus neoformans IC80 0.046 ug ml-1 10.1016/S0960-894X(01)80190-6
Cryptococcus neoformans Cryptococcus neoformans MFC 0.015 ug ml-1 10.1016/j.bmc.2006.09.038
Cryptococcus neoformans Cryptococcus neoformans MFC 0.15 ug ml-1 10.1016/j.bmc.2006.09.038
Cryptococcus neoformans Cryptococcus neoformans MFC 0.25 ug ml-1 10.1016/j.bmc.2006.09.038
Cryptococcus neoformans Cryptococcus neoformans MFC 0.5 ug ml-1 10.1016/j.bmc.2006.09.038
Cryptococcus neoformans Cryptococcus neoformans MIC 0.007 ug.mL-1 10.1016/j.ejmech.2019.03.023
Cryptococcus neoformans Cryptococcus neoformans MIC 0.015 ug.mL-1 10.1016/j.bmc.2007.10.034
Cryptococcus neoformans Cryptococcus neoformans MIC 0.031 ug.mL-1 10.1016/j.ejmech.2022.114161
Cryptococcus neoformans Cryptococcus neoformans MIC 0.06 ug.mL-1 10.1039/C8MD00155C
Cryptococcus neoformans Cryptococcus neoformans MIC 0.06 ug.mL-1 10.1128/aac.00231-10
Cryptococcus neoformans Cryptococcus neoformans MIC 0.0625 ug.mL-1 10.1016/j.bmc.2012.04.045
Cryptococcus neoformans Cryptococcus neoformans MIC 0.0625 ug.mL-1 10.1016/j.ejmech.2019.03.020
Cryptococcus neoformans Cryptococcus neoformans MIC 0.125 ug.mL-1 10.1016/j.ejmech.2010.07.002
Cryptococcus neoformans Cryptococcus neoformans MIC 0.125 ug.mL-1 10.1016/j.ejmech.2019.05.047
Cryptococcus neoformans Cryptococcus neoformans MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113715
Cryptococcus neoformans Cryptococcus neoformans MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113740
Cryptococcus neoformans Cryptococcus neoformans MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113955
Cryptococcus neoformans Cryptococcus neoformans MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113987
Cryptococcus neoformans Cryptococcus neoformans MIC 0.125 ug.mL-1 10.1016/j.ejmech.2022.114195
Cryptococcus neoformans Cryptococcus neoformans MIC 0.25 ug.mL-1 10.1016/j.bmc.2007.10.034
Cryptococcus neoformans Cryptococcus neoformans MIC 0.25 ug.mL-1 10.1016/j.bmcl.2008.10.055
Cryptococcus neoformans Cryptococcus neoformans MIC 0.25 ug.mL-1 10.1016/j.bmcl.2009.02.036
Cryptococcus neoformans Cryptococcus neoformans MIC 0.25 ug.mL-1 10.1016/j.ejmech.2010.10.019
Cryptococcus neoformans Cryptococcus neoformans MIC 0.37 ug.mL-1 10.1039/C8MD00155C
Cryptococcus neoformans Cryptococcus neoformans MIC 0.39 ug.mL-1 10.1016/0960-894X(96)00363-0
Cryptococcus neoformans Cryptococcus neoformans MIC 0.5 ug.mL-1 10.1016/j.bmc.2007.10.034
Cryptococcus neoformans Cryptococcus neoformans MIC 0.625 ug.mL-1 10.1128/aac.00376-07
Cryptococcus neoformans Cryptococcus neoformans MIC 1.0 ug.mL-1 10.1016/j.bmc.2018.04.054
Cryptococcus neoformans Cryptococcus neoformans MIC 1.0 ug.mL-1 10.1016/j.bmcl.2008.04.056
Cryptococcus neoformans Cryptococcus neoformans MIC 1.0 ug.mL-1 10.1016/j.bmcl.2011.06.062
Cryptococcus neoformans Cryptococcus neoformans MIC 1.0 ug.mL-1 10.1016/j.bmcl.2019.07.037
Cryptococcus neoformans Cryptococcus neoformans MIC 1.0 ug.mL-1 10.1016/j.ejmech.2016.07.067
Cryptococcus neoformans Cryptococcus neoformans MIC 1.0 ug.mL-1 10.1016/j.ejmech.2017.05.043
Cryptococcus neoformans Cryptococcus neoformans MIC 1.56 ug.mL-1 10.1039/C8MD00155C
Cryptococcus neoformans Cryptococcus neoformans MIC 40.0 nM 10.1016/j.ejmech.2018.03.083
Cryptococcus neoformans Cryptococcus neoformans MIC 100.0 nM 10.1016/s0960-894x(00)00445-5
Cryptococcus neoformans Cryptococcus neoformans MIC 100.0 nM 10.1016/s0960-894x(00)00551-5
Cryptococcus neoformans Cryptococcus neoformans MIC 156.2 nM 10.6019/CHEMBL4513161
Cryptococcus neoformans Cryptococcus neoformans MIC 156.3 nM 10.6019/CHEMBL4513141
Cryptococcus neoformans Cryptococcus neoformans MIC nan None 10.1016/j.ejmech.2020.112046
Cryptococcus neoformans Cryptococcus neoformans MIC50 0.06 ug.mL-1 10.1128/aac.00231-10
Cryptococcus neoformans Cryptococcus neoformans MIC50 0.5 ug.mL-1 10.1128/aac.00459-07
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.004 ug.mL-1 10.1016/j.bmcl.2010.03.014
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2011.06.008
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2012.02.042
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.0625 ug.mL-1 10.1016/j.ejmech.2011.02.001
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2009.01.048
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2013.11.037
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2008.11.007
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2009.05.018
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2021.113524
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.125 ug.mL-1 10.1021/acs.jmedchem.0c00102
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.125 ug.mL-1 10.1039/C3MD20086H
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.5 ug.mL-1 10.1016/j.bmcl.2009.07.144
Cryptococcus neoformans Cryptococcus neoformans MIC80 0.5 ug.mL-1 10.1016/j.ejmech.2012.04.013
Cryptococcus neoformans Cryptococcus neoformans MIC80 1.0 ug.mL-1 10.1016/j.bmcl.2010.12.006
Cryptococcus neoformans Cryptococcus neoformans MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2007.01.006
Cryptococcus neoformans Cryptococcus neoformans MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2011.02.042
Cryptococcus neoformans Cryptococcus neoformans MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2011.04.022
Cryptococcus neoformans Cryptococcus neoformans MIC80 2.0 ug.mL-1 10.1016/j.bmc.2021.116188
Cryptococcus neoformans Cryptococcus neoformans MIC80 2.0 ug.mL-1 10.1016/j.ejmech.2014.05.079
Cryptococcus neoformans Cryptococcus neoformans MIC80 2.0 ug.mL-1 10.1021/jm051211n
Cryptococcus neoformans Cryptococcus neoformans MIC80 4.0 ug.mL-1 10.1016/j.ejmech.2014.01.009
Cryptococcus neoformans Cryptococcus neoformans MIC80 4.0 ug.mL-1 10.1016/j.ejmech.2017.10.043
Cryptococcus neoformans Cryptococcus neoformans MIC80 4.0 ug.mL-1 10.1021/np500024r
Cryptococcus neoformans Cryptococcus neoformans MIC90 0.125 ug.mL-1 10.1128/aac.00231-10
Cryptococcus neoformans var. neoformans Cryptococcus neoformans var. neoformans MIC50 0.03 ug.mL-1 10.1007/s00044-009-9170-3
Cryptococcus neoformans var. neoformans Cryptococcus neoformans var. neoformans MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
Cryptococcus neoformans var. neoformans Cryptococcus neoformans var. neoformans MIC90 0.5 ug.mL-1 10.1128/aac.01543-08
Cunninghamella Cunninghamella Activity 29.0 % 10.1128/aac.00452-07
Cunninghamella Cunninghamella MFC 4.0 ug ml-1 10.1128/aac.00662-08
Cunninghamella Cunninghamella MIC 0.5 ug.mL-1 10.1128/aac.01467-08
Cunninghamella Cunninghamella MIC 1.75 ug.mL-1 10.1128/aac.00662-08
Cunninghamella Cunninghamella MIC 4.0 ug.mL-1 10.1128/aac.01467-08
Cunninghamella Cunninghamella MIC50 1.0 ug.mL-1 10.1128/aac.00452-07
Cunninghamella Cunninghamella MIC50 1.0 ug.mL-1 10.1128/aac.01539-06
Cunninghamella Cunninghamella MIC90 4.0 ug.mL-1 10.1128/aac.01539-06
Cunninghamella bertholletiae Cunninghamella bertholletiae Activity nan None 10.1128/aac.00786-10
Cunninghamella bertholletiae Cunninghamella bertholletiae MIC 1.0 ug.mL-1 10.1128/aac.00786-10
Cunninghamella bertholletiae Cunninghamella bertholletiae MIC 2.0 ug.mL-1 10.1128/aac.00786-10
Cunninghamella bertholletiae Cunninghamella bertholletiae MIC 3.17 ug.mL-1 10.1128/aac.01467-08
Cunninghamella bertholletiae Cunninghamella bertholletiae MIC 8.0 ug.mL-1 10.1128/aac.00786-10
Cunninghamella bertholletiae Cunninghamella bertholletiae MIC 10.08 ug.mL-1 10.1128/aac.01467-08
Cunninghamella bertholletiae Cunninghamella bertholletiae MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Cunninghamella bertholletiae Cunninghamella bertholletiae MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Curvularia Curvularia MIC 0.008 ug.mL-1 10.1128/aac.01475-07
Curvularia Curvularia MIC50 0.06 ug.mL-1 10.1128/aac.01475-07
Curvularia Curvularia MIC90 16.0 ug.mL-1 10.1128/aac.01475-07
Curvularia australiensis Curvularia australiensis MFC 0.5 ug ml-1 10.1128/aac.00662-08
Curvularia australiensis Curvularia australiensis MIC 0.12 ug.mL-1 10.1128/aac.00662-08
Curvularia lunata Curvularia lunata MFC 0.5 ug ml-1 10.1128/aac.00662-08
Curvularia lunata Curvularia lunata MIC 0.03 ug.mL-1 10.1128/aac.00662-08
Cutaneotrichosporon cutaneum Cutaneotrichosporon cutaneum MIC 8.0 ug.mL-1 10.1039/C7MD00442G
Cyberlindnera jadinii Cyberlindnera jadinii MIC 0.06 ug.mL-1 10.1016/j.ejmech.2016.02.013
Cyberlindnera jadinii Cyberlindnera jadinii MIC 0.25 ug.mL-1 10.1039/C7MD00442G
Cyberlindnera jadinii Cyberlindnera jadinii MIC 0.5 ug.mL-1 10.1016/j.ejmech.2015.04.047
Debaryomyces hansenii Debaryomyces hansenii MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
Debaryomyces hansenii Debaryomyces hansenii MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Diutina rugosa Diutina rugosa MIC 0.03 ug.mL-1 10.1128/aac.01368-08
Diutina rugosa Diutina rugosa MIC 0.12 ug.mL-1 10.1039/C8MD00155C
Diutina rugosa Diutina rugosa MIC50 0.06 ug.mL-1 10.1128/aac.00459-07
Diutina rugosa Diutina rugosa MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
Diutina rugosa Diutina rugosa MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Epidermophyton floccosum Epidermophyton floccosum MFC nan None None
Epidermophyton floccosum Epidermophyton floccosum MIC 0.125 ug.mL-1 10.1016/j.bmcl.2013.03.098
Epidermophyton floccosum Epidermophyton floccosum MIC 0.19 ug.mL-1 10.1016/j.ejmech.2020.112768
Epidermophyton floccosum Epidermophyton floccosum MIC 0.226 ug.mL-1 10.1128/aac.01382-06
Epidermophyton floccosum Epidermophyton floccosum MIC 0.25 ug.mL-1 10.1016/j.bmcl.2013.03.098
Epidermophyton floccosum Epidermophyton floccosum MIC50 0.032 ug.mL-1 10.1021/jm0494772
Epidermophyton floccosum Epidermophyton floccosum MIC90 0.093 ug.mL-1 10.1021/jm0494772
Escherichia coli Escherichia coli MIC 6.25 ug.mL-1 10.1016/j.ejmech.2019.111744
Escherichia coli Escherichia coli MIC 10000.0 nM 10.6019/CHEMBL4513141
Escherichia coli Escherichia coli MIC 20000.0 nM 10.6019/CHEMBL4513161
Escherichia coli Escherichia coli MIC nan None 10.1016/j.bmcl.2015.10.028
Escherichia coli Escherichia coli MIC nan None 10.1016/j.bmcl.2019.02.033
Exophiala dermatitidis Exophiala dermatitidis MIC 0.5 ug.mL-1 10.1016/j.ejmech.2014.02.019
Exophiala dermatitidis Exophiala dermatitidis MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
Exophiala dermatitidis Exophiala dermatitidis MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Exophiala spinifera Exophiala spinifera MIC 0.06 ug.mL-1 10.1016/j.ejmech.2010.10.019
Exserohilum rostratum Exserohilum rostratum IZ 3.56 mm 10.1007/s00044-013-0543-2
Exserohilum rostratum Exserohilum rostratum IZ 3.58 mm 10.1007/s00044-013-0573-9
Exserohilum rostratum Exserohilum rostratum IZ 7.56 mm 10.1007/s00044-013-0543-2
Exserohilum rostratum Exserohilum rostratum IZ 7.56 mm 10.1007/s00044-013-0573-9
Exserohilum rostratum Exserohilum rostratum IZ 14.76 mm 10.1007/s00044-013-0543-2
Exserohilum rostratum Exserohilum rostratum IZ 14.76 mm 10.1007/s00044-013-0573-9
Exserohilum rostratum Exserohilum rostratum IZ 27.36 mm 10.1007/s00044-013-0543-2
Exserohilum rostratum Exserohilum rostratum IZ 29.56 mm 10.1007/s00044-013-0573-9
Fonsecaea compacta Fonsecaea compacta MIC 0.0625 ug.mL-1 10.1016/j.bmcl.2008.04.056
Fonsecaea compacta Fonsecaea compacta MIC80 0.25 ug.mL-1 10.1016/j.ejmech.2007.01.006
Fonsecaea monophora Fonsecaea monophora Activity nan None 10.1128/aac.01284-09
Fonsecaea monophora Fonsecaea monophora MIC 0.031 ug.mL-1 10.1128/aac.01655-09
Fonsecaea monophora Fonsecaea monophora MIC 0.25 ug.mL-1 10.1128/aac.01284-09
Fonsecaea monophora Fonsecaea monophora MIC 0.5 ug.mL-1 10.1128/aac.01284-09
Fonsecaea monophora Fonsecaea monophora MIC50 0.063 ug.mL-1 10.1128/aac.01655-09
Fonsecaea monophora Fonsecaea monophora MIC90 0.125 ug.mL-1 10.1128/aac.01655-09
Fonsecaea pedrosoi Fonsecaea pedrosoi MIC 0.031 ug.mL-1 10.1128/aac.01655-09
Fonsecaea pedrosoi Fonsecaea pedrosoi MIC50 0.063 ug.mL-1 10.1128/aac.01655-09
Fonsecaea pedrosoi Fonsecaea pedrosoi MIC80 0.5 ug.mL-1 10.1021/jm051211n
Fonsecaea pedrosoi Fonsecaea pedrosoi MIC90 0.125 ug.mL-1 10.1128/aac.01655-09
Fusarium Fusarium MIC80 0.25 ug.mL-1 10.1016/j.bmcl.2010.12.006
Fusarium equiseti Fusarium equiseti MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Fusarium equiseti Fusarium equiseti MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Fusarium oxysporum Fusarium oxysporum IZ 4.82 mm 10.1007/s00044-013-0573-9
Fusarium oxysporum Fusarium oxysporum IZ 5.46 mm 10.1007/s00044-013-0543-2
Fusarium oxysporum Fusarium oxysporum IZ 10.8 mm 10.1007/s00044-013-0543-2
Fusarium oxysporum Fusarium oxysporum IZ 10.8 mm 10.1007/s00044-013-0573-9
Fusarium oxysporum Fusarium oxysporum IZ 20.03 mm 10.1007/s00044-013-0543-2
Fusarium oxysporum Fusarium oxysporum IZ 20.03 mm 10.1007/s00044-013-0573-9
Fusarium oxysporum Fusarium oxysporum IZ 34.35 mm 10.1007/s00044-013-0543-2
Fusarium oxysporum Fusarium oxysporum IZ 39.63 mm 10.1007/s00044-013-0573-9
Fusarium oxysporum Fusarium oxysporum MFC 0.25 ug ml-1 10.1128/aac.00662-08
Fusarium oxysporum Fusarium oxysporum MIC 4.5 ug.mL-1 10.1128/aac.00662-08
Fusarium oxysporum Fusarium oxysporum MIC 16.0 ug.mL-1 10.1128/aac.00272-08
Fusarium oxysporum Fusarium oxysporum MIC nan None 10.1016/j.ejmech.2010.06.029
Fusarium oxysporum Fusarium oxysporum MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Fusarium oxysporum Fusarium oxysporum MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Fusarium proliferatum Fusarium proliferatum MIC 16.0 ug.mL-1 10.1128/aac.00272-08
Fusarium proliferatum Fusarium proliferatum MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Fusarium proliferatum Fusarium proliferatum MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Fusarium solani Fusarium solani MFC 8.0 ug ml-1 10.1128/aac.00662-08
Fusarium solani Fusarium solani MIC 6.0 ug.mL-1 10.1128/aac.00662-08
Fusarium solani Fusarium solani MIC 16.0 ug.mL-1 10.1128/aac.00272-08
Fusarium solani Fusarium solani MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Fusarium solani Fusarium solani MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Fusarium sp. Fusarium sp. MIC 0.008 ug.mL-1 10.1128/aac.01475-07
Fusarium sp. Fusarium sp. MIC 16.0 ug.mL-1 10.1016/j.ejmech.2020.112082
Fusarium sp. Fusarium sp. MIC50 0.06 ug.mL-1 10.1128/aac.01475-07
Fusarium sp. Fusarium sp. MIC90 16.0 ug.mL-1 10.1128/aac.00714-09
Fusarium sp. Fusarium sp. MIC90 16.0 ug.mL-1 10.1128/aac.01475-07
Fusarium subglutinans Fusarium subglutinans MIC 10.8 ug.mL-1 10.1128/aac.00272-08
Fusarium verticillioides Fusarium verticillioides MIC 3.33 ug.mL-1 10.1128/aac.00272-08
Fusarium verticillioides Fusarium verticillioides MIC 12.7 ug.mL-1 10.1128/aac.00176-08
Fusarium verticillioides Fusarium verticillioides MIC 16.0 ug.mL-1 10.1128/aac.00176-08
Fusarium verticillioides Fusarium verticillioides MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Fusarium verticillioides Fusarium verticillioides MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Geotrichum candidum Geotrichum candidum IZ 24.2 mm 10.1016/j.ejmech.2016.11.019
Geotrichum candidum Geotrichum candidum IZ 27.0 mm 10.1016/j.ejmech.2011.07.035
Geotrichum candidum Geotrichum candidum IZ 27.0 mm 10.1016/j.ejmech.2011.08.018
Geotrichum candidum Geotrichum candidum MFC 8.0 ug ml-1 10.1128/aac.00662-08
Geotrichum candidum Geotrichum candidum MIC 1.45 ug.mL-1 10.1128/aac.00662-08
Geotrichum candidum Geotrichum candidum MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Geotrichum candidum Geotrichum candidum MIC90 2.0 ug.mL-1 10.1128/aac.01543-08
Hanseniaspora uvarum Hanseniaspora uvarum MIC50 0.25 ug.mL-1 10.1128/aac.00459-07
Histoplasma capsulatum Histoplasma capsulatum IC50 0.001 ug.mL-1 10.1021/acs.jnatprod.9b00121
Histoplasma capsulatum Histoplasma capsulatum MIC 0.001 ug.mL-1 10.1021/acs.jnatprod.7b01067
Homo sapiens 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase IC50 4700.0 nM None
Homo sapiens A549 Activity 3.84 % 10.1016/j.bmcl.2022.129011
Homo sapiens A549 Activity 7.65 % 10.1016/j.bmcl.2022.129011
Homo sapiens A549 Activity 34.0 % 10.1016/j.bmcl.2022.129011
Homo sapiens A549 Activity 34.6 % 10.1016/j.bmcl.2022.129011
Homo sapiens A549 Activity 36.3 % 10.1016/j.bmcl.2022.129011
Homo sapiens A549 Activity 38.3 % 10.1016/j.bmcl.2022.129011
Homo sapiens A549 Activity 53.9 % 10.1016/j.bmcl.2022.129011
Homo sapiens A549 IC50 182.0 ug.mL-1 10.1016/j.bmcl.2014.01.060
Homo sapiens A549 IC50 3000.0 nM 10.1016/j.bmcl.2022.129011
Homo sapiens A549 IC50 30000.0 nM 10.1016/j.ejmech.2021.113740
Homo sapiens A549 IC50 50000.0 nM 10.1016/j.ejmech.2021.113955
Homo sapiens Acetylcholinesterase IC50 nan None None
Homo sapiens Acetylcholinesterase Ki nan None None
Homo sapiens Adenosine A1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A1 receptor IC50 nan None None
Homo sapiens Adenosine A1 receptor Ki nan None None
Homo sapiens Adenosine A2a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A2a receptor IC50 nan None None
Homo sapiens Adenosine A2a receptor Ki nan None None
Homo sapiens Adenosine A3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Adenosine A3 receptor IC50 nan None None
Homo sapiens Adenosine A3 receptor Ki nan None None
Homo sapiens Alpha-1a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-1d adrenergic receptor IC50 nan None None
Homo sapiens Alpha-1d adrenergic receptor Ki nan None None
Homo sapiens Alpha-2a adrenergic receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2a adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2a adrenergic receptor Ki nan None None
Homo sapiens Alpha-2b adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2b adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2b adrenergic receptor Ki nan None None
Homo sapiens Alpha-2c adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Alpha-2c adrenergic receptor IC50 nan None None
Homo sapiens Alpha-2c adrenergic receptor Ki nan None None
Homo sapiens Alpha-synuclein Potency 2238.7 nM None
Homo sapiens Angiotensin II type 2 (AT-2) receptor IC50 nan None None
Homo sapiens Angiotensin II type 2 (AT-2) receptor Ki nan None None
Homo sapiens Arachidonate 15-lipoxygenase, type II Potency 4466.8 nM None
Homo sapiens ATP-binding cassette sub-family G member 2 Activity nan None 10.1021/acs.jmedchem.8b01283
Homo sapiens ATP-binding cassette sub-family G member 2 IC50 2000.0 nM 10.1016/j.ejmech.2022.114346
Homo sapiens Beta-1 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-1 adrenergic receptor IC50 nan None None
Homo sapiens Beta-1 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-2 adrenergic receptor IC50 nan None None
Homo sapiens Beta-2 adrenergic receptor Ki nan None None
Homo sapiens Beta-2 adrenergic receptor Potency 15848.9 nM None
Homo sapiens Beta-3 adrenergic receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Beta-3 adrenergic receptor IC50 nan None None
Homo sapiens Beta-3 adrenergic receptor Ki nan None None
Homo sapiens Bile acid receptor FXR AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump AC50 660.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bile salt export pump IC50 18000.0 nM 10.1093/toxsci/kfq269
Homo sapiens Bile salt export pump IC50 18000.0 nM 10.1093/toxsci/kft176
Homo sapiens Bradykinin B1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Bradykinin B2 receptor IC50 nan None None
Homo sapiens Bradykinin B2 receptor Ki nan None None
Homo sapiens Bromodomain adjacent to zinc finger domain protein 2B Potency 19952.6 nM None
Homo sapiens Calcitonin receptor IC50 nan None None
Homo sapiens Calcitonin receptor Ki nan None None
Homo sapiens Calcium release-activated calcium channel protein 1 Inhibition 10.0 % 10.1016/j.bmc.2016.11.007
Homo sapiens Canalicular multispecific organic anion transporter 1 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Canalicular multispecific organic anion transporter 2 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Cannabinoid CB1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cannabinoid CB1 receptor IC50 nan None None
Homo sapiens Cannabinoid CB1 receptor Ki nan None None
Homo sapiens Carbonic anhydrase II IC50 nan None None
Homo sapiens Carbonic anhydrase II Ki nan None None
Homo sapiens Caspase-1 IC50 nan None None
Homo sapiens Caspase-1 Ki nan None None
Homo sapiens Cathepsin G IC50 nan None None
Homo sapiens Cathepsin G Ki nan None None
Homo sapiens C-C chemokine receptor type 2 IC50 nan None None
Homo sapiens C-C chemokine receptor type 2 Ki nan None None
Homo sapiens C-C chemokine receptor type 4 IC50 200.0 nM 10.1021/jm301749y
Homo sapiens C-C chemokine receptor type 4 IC50 500.0 nM 10.1021/jm301749y
Homo sapiens C-C chemokine receptor type 4 IC50 501.19 nM 10.1021/jm301749y
Homo sapiens C-C chemokine receptor type 4 IC50 7200.0 nM 10.1021/jm301749y
Homo sapiens C-C chemokine receptor type 4 IC50 7943.28 nM 10.1021/jm301749y
Homo sapiens C-C chemokine receptor type 4 IC50 11400.0 nM 10.1021/jm301749y
Homo sapiens C-C chemokine receptor type 4 IC50 12589.25 nM 10.1021/jm301749y
Homo sapiens C-C chemokine receptor type 4 IC50 nan None None
Homo sapiens C-C chemokine receptor type 4 Ki nan None None
Homo sapiens C-C chemokine receptor type 5 IC50 nan None None
Homo sapiens C-C chemokine receptor type 5 Ki nan None None
Homo sapiens Cholecystokinin A receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cholecystokinin A receptor IC50 nan None None
Homo sapiens Cholecystokinin A receptor Ki nan None None
Homo sapiens Cholecystokinin B receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Corticotropin releasing factor receptor 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Corticotropin releasing factor receptor 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-1 IC50 nan None None
Homo sapiens Cyclooxygenase-1 Ki nan None None
Homo sapiens Cyclooxygenase-2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Cyclooxygenase-2 IC50 nan None None
Homo sapiens Cyclooxygenase-2 Ki nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 IC50 nan None None
Homo sapiens Cysteinyl leukotriene receptor 1 Ki nan None None
Homo sapiens Cytochrome P450 1A2 IC50 nan None None
Homo sapiens Cytochrome P450 1A2 Ki nan None None
Homo sapiens Cytochrome P450 2A6 IC50 nan None None
Homo sapiens Cytochrome P450 2A6 Ki nan None None
Homo sapiens Cytochrome P450 2C19 IC50 nan None None
Homo sapiens Cytochrome P450 2C19 Ki nan None None
Homo sapiens Cytochrome P450 2C9 IC50 nan None None
Homo sapiens Cytochrome P450 2C9 Ki nan None None
Homo sapiens Cytochrome P450 2D6 IC50 nan None None
Homo sapiens Cytochrome P450 2D6 Ki nan None None
Homo sapiens Cytochrome P450 2E1 IC50 nan None None
Homo sapiens Cytochrome P450 2E1 Ki nan None None
Homo sapiens Cytochrome P450 3A4 Activity nan None None
Homo sapiens Cytochrome P450 3A4 IC50 32.6 nM 10.1016/j.bmc.2016.11.051
Homo sapiens Cytochrome P450 3A4 IC50 32.6 nM 10.1016/j.ejmech.2021.113715
Homo sapiens Cytochrome P450 3A4 IC50 40.0 nM 10.1016/j.ejmech.2018.11.056
Homo sapiens Cytochrome P450 3A4 IC50 50.4 nM 10.1021/acs.jmedchem.5b01718
Homo sapiens Cytochrome P450 3A4 IC50 70.0 nM 10.1016/j.bmcl.2014.05.068
Homo sapiens Cytochrome P450 3A4 IC50 700.0 nM 10.1021/jm021012t
Homo sapiens Cytochrome P450 3A4 IC50 900.0 nM None
Homo sapiens Cytochrome P450 3A4 Inhibition 0.04 % 10.1021/acs.jmedchem.8b01283
Homo sapiens Cytochrome P450 3A4 Inhibition 84.0 % 10.1021/acs.jmedchem.8b01252
Homo sapiens Cytochrome P450 3A4 K 0.2 mM 10.1074/jbc.m610346200
Homo sapiens Cytochrome P450 3A4 Ki nan None None
Homo sapiens Cytochrome P450 51 IC50 0.06 ug.mL-1 10.1016/S0960-894X(01)80190-6
Homo sapiens Cytochrome P450 51 IC50 3600.0 nM 10.1124/dmd.106.013888
Homo sapiens Delta opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Delta opioid receptor IC50 nan None None
Homo sapiens Delta opioid receptor Ki nan None None
Homo sapiens DNA polymerase kappa Potency 44668.4 nM None
Homo sapiens Dopamine D1 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D1 receptor IC50 nan None None
Homo sapiens Dopamine D1 receptor Ki nan None None
Homo sapiens Dopamine D2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D2 receptor IC50 nan None None
Homo sapiens Dopamine D2 receptor Ki nan None None
Homo sapiens Dopamine D3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D3 receptor IC50 nan None None
Homo sapiens Dopamine D3 receptor Ki nan None None
Homo sapiens Dopamine D4 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine D4 receptor IC50 nan None None
Homo sapiens Dopamine D4 receptor Ki nan None None
Homo sapiens Dopamine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Dopamine transporter IC50 nan None None
Homo sapiens Dopamine transporter Ki nan None None
Homo sapiens Endothelin receptor ET-A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Endothelin receptor ET-A IC50 nan None None
Homo sapiens Endothelin receptor ET-A Ki nan None None
Homo sapiens Endothelin receptor ET-B AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Epidermal growth factor receptor erbB1 IC50 nan None None
Homo sapiens Epidermal growth factor receptor erbB1 Ki nan None None
Homo sapiens Equilibrative nucleoside transporter 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor alpha IC50 nan None None
Homo sapiens Estrogen receptor alpha Ki nan None None
Homo sapiens Estrogen receptor beta AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Estrogen receptor beta IC50 nan None None
Homo sapiens Estrogen receptor beta Ki nan None None
Homo sapiens GABA-B receptor 1 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Galactocerebrosidase Potency 631.0 nM None
Homo sapiens Gastric inhibitory polypeptide receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Geminin Potency 819.9 nM None
Homo sapiens Geminin Potency 1835.6 nM None
Homo sapiens Geminin Potency 11885.6 nM None
Homo sapiens Ghrelin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucagon receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Glucocorticoid receptor IC50 nan None None
Homo sapiens Glucocorticoid receptor Ki nan None None
Homo sapiens Heat shock protein HSP 90-alpha AC50 195.0 nM None
Homo sapiens HEK293 Activity 90.76 % 10.1016/j.ejmech.2018.03.083
Homo sapiens HEK293 CC50 10000.0 nM 10.6019/CHEMBL4513141
Homo sapiens HEK293 CC50 20000.0 nM 10.6019/CHEMBL4513161
Homo sapiens HEK293 IC50 250000.0 nM 10.1016/j.ejmech.2018.03.083
Homo sapiens HEK-293T IC50 50000.0 nM 10.1016/j.ejmech.2021.113955
Homo sapiens HepG2 IC50 142.0 ug.mL-1 10.1016/j.bmcl.2014.01.060
Homo sapiens HepG2 IC50 7870.0 nM 10.1016/j.bmcl.2022.129011
Homo sapiens HepG2 IC50 50000.0 nM 10.1016/j.ejmech.2021.113955
Homo sapiens HERG AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens HERG IC50 40000.0 nM 10.1021/jm4016284
Homo sapiens HERG IC50 nan None None
Homo sapiens HERG Inhibition 1.0 % 10.1016/j.ejmech.2018.11.056
Homo sapiens HERG Inhibition 1.0 % 10.1021/acs.jmedchem.8b01283
Homo sapiens HERG Ki nan None None
Homo sapiens Histamine H1 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H1 receptor IC50 nan None None
Homo sapiens Histamine H1 receptor Ki nan None None
Homo sapiens Histamine H2 receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histamine H2 receptor IC50 nan None None
Homo sapiens Histamine H2 receptor Ki nan None None
Homo sapiens Histamine H3 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Potency 1584.9 nM None
Homo sapiens HMG-CoA reductase IC50 nan None None
Homo sapiens HMG-CoA reductase Ki nan None None
Homo sapiens Homo sapiens Activity nan None 10.1128/aac.00297-07
Homo sapiens Homo sapiens AUC 905.09 ng.hr.mL-1 None
Homo sapiens Homo sapiens AUC 2121.0 ng.hr.mL-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens AUC 2270.0 ng.hr.mL-1 None
Homo sapiens Homo sapiens AUC 2669.0 ng.hr.mL-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens AUC 3133.0 ng.hr.mL-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens AUC 3340.0 ng.hr.mL-1 None
Homo sapiens Homo sapiens AUC 3765.0 ng.hr.mL-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens AUC 3811.0 ng.hr.mL-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens AUC 4155.0 ng.hr.mL-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens AUC 4166.0 ng.hr.mL-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens AUC 4249.0 ng.hr.mL-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens AUC 4922.0 ng.hr.mL-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens AUC 6134.92 ng.hr.mL-1 10.1093/toxsci/kft176
Homo sapiens Homo sapiens AUC 9046.81 ng.hr.mL-1 None
Homo sapiens Homo sapiens AUC 9510.0 ng.hr.mL-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens AUC 20500.0 ng.hr.mL-1 10.1128/aac.00530-08
Homo sapiens Homo sapiens CL 5.1 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL 5.1 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens CL 8.817 mL.min-1.kg-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens CL 10.35 mL.min-1.kg-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens CL 11.71 mL.min-1.kg-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens CL 12.95 mL.min-1.kg-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens CL 19.05 mL.min-1.kg-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens CL_renal 0.0 mL.min-1.kg-1 10.1021/jm900403j
Homo sapiens Homo sapiens CL_renal 0.0 mL.min-1.kg-1 10.1021/jm901371v
Homo sapiens Homo sapiens Cmax 165.52 nM None
Homo sapiens Homo sapiens Cmax 229.58 nM None
Homo sapiens Homo sapiens Cmax 301.85 nM None
Homo sapiens Homo sapiens Cmax 375.54 nM 10.1128/aac.00297-07
Homo sapiens Homo sapiens Cmax 392.55 nM 10.1128/aac.00297-07
Homo sapiens Homo sapiens Cmax 415.22 nM 10.1128/aac.00297-07
Homo sapiens Homo sapiens Cmax 423.72 nM 10.1128/aac.00297-07
Homo sapiens Homo sapiens Cmax 454.9 nM 10.1128/aac.00297-07
Homo sapiens Homo sapiens Cmax 651.88 nM 10.1128/aac.00530-08
Homo sapiens Homo sapiens Cmax 932.62 nM None
Homo sapiens Homo sapiens Cmax 1112.45 nM 10.1128/aac.00297-07
Homo sapiens Homo sapiens Cmax 1142.21 nM 10.1128/aac.00297-07
Homo sapiens Homo sapiens Cmax 1171.97 nM 10.1128/aac.00297-07
Homo sapiens Homo sapiens Cmax 1438.39 nM 10.1128/aac.00297-07
Homo sapiens Homo sapiens Cmax 2200.81 nM 10.1128/aac.00297-07
Homo sapiens Homo sapiens Css 0.362 uM 10.1093/toxsci/kft176
Homo sapiens Homo sapiens DILI_Concern nan None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens DILI_severity_class 8.0 None 10.1016/j.drudis.2016.02.015
Homo sapiens Homo sapiens F 55.0 % 10.1016/j.bmc.2007.08.060
Homo sapiens Homo sapiens Fa 0.85 None 10.1021/jm901371v
Homo sapiens Homo sapiens F_fraction 0.55 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fg 0.83 None 10.1021/jm901371v
Homo sapiens Homo sapiens Fh 0.78 None 10.1021/jm901371v
Homo sapiens Homo sapiens Ratio 0.02 None 10.1093/toxsci/kft176
Homo sapiens Homo sapiens T1/2 12.3 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens T1/2 12.7 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens T1/2 13.3 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens T1/2 14.0 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens T1/2 14.3 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens T1/2 16.6 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens T1/2 17.2 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens T1/2 20.2 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens T1/2 27.0 hr 10.1128/aac.00530-08
Homo sapiens Homo sapiens T1/2 29.0 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens T1/2 36.84 hr None
Homo sapiens Homo sapiens Tmax 1.2 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens Tmax 1.7 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens Tmax 2.2 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens Tmax 2.9 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens Tmax 2.9 hr None
Homo sapiens Homo sapiens Tmax 4.0 hr 10.1128/aac.00297-07
Homo sapiens Homo sapiens Tmax 4.0 hr None
Homo sapiens Homo sapiens Tmax 4.6 hr None
Homo sapiens Homo sapiens Tmax 24.0 hr 10.1128/aac.00530-08
Homo sapiens Homo sapiens Vd 8.3 L.kg-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens Vd 13.9 L.kg-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens Vd 18.5 L.kg-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens Vd 23.6 L.kg-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens Vd 28.5 L.kg-1 10.1128/aac.00297-07
Homo sapiens Homo sapiens Vdss 7.4 L.kg-1 10.1021/jm901371v
Homo sapiens HUVEC Activity nan None 10.1021/acsmedchemlett.9b00438
Homo sapiens HUVEC GI50 400.0 nM 10.1021/acs.jmedchem.5b01718
Homo sapiens HUVEC IC50 160.0 nM 10.1021/acs.jmedchem.5b01718
Homo sapiens HUVEC IC50 170.0 nM 10.1021/acs.jmedchem.8b01252
Homo sapiens HUVEC Inhibition 45.0 % 10.1021/acs.jmedchem.8b01252
Homo sapiens HUVEC Inhibition nan % 10.1021/acs.jmedchem.5b01718
Homo sapiens HUVEC Ratio IC50 1.0 None 10.1021/jm200944b
Homo sapiens Hypoxia-inducible factor 1 alpha Potency 2511.9 nM None
Homo sapiens Interleukin-8 receptor A IC50 100.0 nM 10.1021/jm301749y
Homo sapiens Interleukin-8 receptor A IC50 158.49 nM 10.1021/jm301749y
Homo sapiens Interleukin-8 receptor A IC50 5000.0 nM 10.1021/jm301749y
Homo sapiens Interleukin-8 receptor A IC50 5011.87 nM 10.1021/jm301749y
Homo sapiens Interleukin-8 receptor A IC50 19952.62 nM 10.1021/jm301749y
Homo sapiens Interleukin-8 receptor A IC50 20800.0 nM 10.1021/jm301749y
Homo sapiens Interleukin-8 receptor A IC50 nan None None
Homo sapiens Interleukin-8 receptor A Ki nan None None
Homo sapiens Interleukin-8 receptor B IC50 nan None None
Homo sapiens Interleukin-8 receptor B Ki nan None None
Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic Potency 2909.3 nM None
Homo sapiens Kappa opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Kappa opioid receptor IC50 nan None None
Homo sapiens Kappa opioid receptor Ki nan None None
Homo sapiens L02 IC50 50000.0 nM 10.1016/j.bmcl.2022.129011
Homo sapiens Leukocyte common antigen IC50 nan None None
Homo sapiens Leukocyte common antigen Ki nan None None
Homo sapiens Leukocyte elastase IC50 nan None None
Homo sapiens Leukocyte elastase Ki nan None None
Homo sapiens LXR-alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens LXR-beta AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Lysine-specific demethylase 4A Potency 7943.3 nM None
Homo sapiens MAP kinase ERK1 IC50 nan None None
Homo sapiens MAP kinase ERK1 Ki nan None None
Homo sapiens MAP kinase ERK2 IC50 nan None None
Homo sapiens MAP kinase ERK2 Ki nan None None
Homo sapiens MAP kinase ERK2 Potency 14125.4 nM None
Homo sapiens MAP kinase p38 alpha IC50 nan None None
Homo sapiens MAP kinase p38 alpha Ki nan None None
Homo sapiens Matrix metalloproteinase-1 IC50 nan None None
Homo sapiens Matrix metalloproteinase-1 Ki nan None None
Homo sapiens Matrix metalloproteinase 9 IC50 nan None None
Homo sapiens Matrix metalloproteinase 9 Ki nan None None
Homo sapiens MCF7 IC50 30000.0 nM 10.1016/j.ejmech.2021.113740
Homo sapiens MCF7 IC50 50000.0 nM 10.1016/j.ejmech.2021.113955
Homo sapiens Melanocortin receptor 3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 3 IC50 nan None None
Homo sapiens Melanocortin receptor 3 Ki nan None None
Homo sapiens Melanocortin receptor 4 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Melanocortin receptor 4 IC50 nan None None
Homo sapiens Melanocortin receptor 4 Ki nan None None
Homo sapiens Melanocortin receptor 5 IC50 nan None None
Homo sapiens Melanocortin receptor 5 Ki nan None None
Homo sapiens Menin/Histone-lysine N-methyltransferase MLL Potency 631.0 nM None
Homo sapiens Menin/Histone-lysine N-methyltransferase MLL Potency 3162.3 nM None
Homo sapiens Microtubule-associated protein tau Potency 1412.5 nM None
Homo sapiens Microtubule-associated protein tau Potency 1995.3 nM None
Homo sapiens Microtubule-associated protein tau Potency 2511.9 nM None
Homo sapiens Microtubule-associated protein tau Potency 3162.3 nM None
Homo sapiens Microtubule-associated protein tau Potency 3981.1 nM None
Homo sapiens Monoamine oxidase A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Monoamine oxidase A IC50 nan None None
Homo sapiens Monoamine oxidase A Ki nan None None
Homo sapiens Motilin receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens MRC5 CC50 49330.0 nM 10.1128/aac.00730-10
Homo sapiens Multidrug resistance-associated protein 4 IC50 133000.0 nM 10.1093/toxsci/kft176
Homo sapiens Mu opioid receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Mu opioid receptor IC50 nan None None
Homo sapiens Mu opioid receptor Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M1 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M1 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M2 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M2 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M3 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M3 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M4 Ki nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Muscarinic acetylcholine receptor M5 IC50 nan None None
Homo sapiens Muscarinic acetylcholine receptor M5 Ki nan None None
Homo sapiens Neurokinin 1 receptor AC50 1543.2 nM 10.1038/s41467-023-40064-9
Homo sapiens Neurokinin 1 receptor IC50 nan None None
Homo sapiens Neurokinin 1 receptor Ki nan None None
Homo sapiens Neurokinin 2 receptor IC50 nan None None
Homo sapiens Neurokinin 2 receptor Ki nan None None
Homo sapiens Neuronal acetylcholine receptor protein alpha-4 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 1 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 1 Ki nan None None
Homo sapiens Neuropeptide Y receptor type 2 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Neuropeptide Y receptor type 2 IC50 nan None None
Homo sapiens Neuropeptide Y receptor type 2 Ki nan None None
Homo sapiens Neurotensin receptor 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Niemann-Pick C1 protein Activity nan None 10.1021/acs.jmedchem.8b01252
Homo sapiens Niemann-Pick C1 protein Inhibition nan % 10.1021/acsmedchemlett.9b00438
Homo sapiens Norepinephrine transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Norepinephrine transporter IC50 nan None None
Homo sapiens Norepinephrine transporter Ki nan None None
Homo sapiens Nuclear factor erythroid 2-related factor 2 Potency 2059.6 nM None
Homo sapiens Nuclear receptor subfamily 1 group I member 3 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens PBMC IC50 1530.0 nM 10.1016/j.bmcl.2014.01.022
Homo sapiens Peroxisome proliferator-activated receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens P-glycoprotein 1 Activity 2.0 % 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 Activity 18.0 nM/mg*min 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 Activity nan None 10.1006/bbrc.2001.6000
Homo sapiens P-glycoprotein 1 Activity nan None 10.1021/acs.jmedchem.8b01283
Homo sapiens P-glycoprotein 1 Activity nan None 10.1248/bpb.22.1355
Homo sapiens P-glycoprotein 1 IC50 30.0 nM 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 IC50 1700.0 nM 10.1128/aac.46.1.160-165.2002
Homo sapiens P-glycoprotein 1 IC50 2100.0 nM 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 IC50 2400.0 nM 10.1006/bbrc.2001.6000
Homo sapiens P-glycoprotein 1 Inhibition 2.0 % 10.1021/jm021012t
Homo sapiens P-glycoprotein 1 % maximum response -0.23 % None
Homo sapiens P-glycoprotein 1 Papp 552.0 nm/s None
Homo sapiens P-glycoprotein 1 Papp 571.0 nm/s None
Homo sapiens P-glycoprotein 1 Ratio_ATPase activity 1.2 None None
Homo sapiens P-glycoprotein 1 Ratio_Papp 0.97 None None
Homo sapiens Phosphodiesterase 3A AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 4D AC50 17999.9 nM 10.1038/s41467-023-40064-9
Homo sapiens Phosphodiesterase 5A IC50 nan None None
Homo sapiens Phosphodiesterase 5A Ki nan None None
Homo sapiens Plasma AUC 34400.0 ng.hr.mL-1 10.1128/aac.00663-08
Homo sapiens Plasma Cmax 2975.98 nM 10.1128/aac.00663-08
Homo sapiens Plasma Cmin 1.46 ug ml-1 10.1128/aac.01807-09
Homo sapiens Plasma Fu 0.0018 None 10.1128/aac.00530-08
Homo sapiens Plasma Stability 114.5 % 10.1128/aac.01807-09
Homo sapiens Platelet activating factor receptor IC50 nan None None
Homo sapiens Platelet activating factor receptor Ki nan None None
Homo sapiens Pregnane X receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Prelamin-A/C Potency 4466.8 nM None
Homo sapiens Progesterone receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Protein kinase C alpha IC50 nan None None
Homo sapiens Protein kinase C alpha Ki nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 nan None None
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Ki nan None None
Homo sapiens Retinoic acid receptor alpha AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Retinoic acid receptor beta AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Retinoic acid receptor gamma AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform IC50 nan None None
Homo sapiens Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform Ki nan None None
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 1a (5-HT1a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2a (5-HT2a) receptor IC50 nan None None
Homo sapiens Serotonin 2a (5-HT2a) receptor Ki nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2b (5-HT2b) receptor IC50 nan None None
Homo sapiens Serotonin 2b (5-HT2b) receptor Ki nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 2c (5-HT2c) receptor IC50 nan None None
Homo sapiens Serotonin 2c (5-HT2c) receptor Ki nan None None
Homo sapiens Serotonin 3a (5-HT3a) receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin 6 (5-HT6) receptor IC50 nan None None
Homo sapiens Serotonin 6 (5-HT6) receptor Ki nan None None
Homo sapiens Serotonin 7 (5-HT7) receptor AC50 10000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Serotonin transporter IC50 nan None None
Homo sapiens Serotonin transporter Ki nan None None
Homo sapiens Serum albumin Log K' 1.04 None 10.1021/jm010960b
Homo sapiens Sigma opioid receptor IC50 nan None None
Homo sapiens Sigma opioid receptor Ki nan None None
Homo sapiens Smoothened homolog Inhibition nan % 10.1021/acs.jmedchem.6b01247
Homo sapiens Solute carrier organic anion transporter family member 1B1 Inhibition 22.3 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 1B3 Inhibition -2.3 % 10.1021/jm300212s
Homo sapiens Solute carrier organic anion transporter family member 2B1 Inhibition 59.8 % 10.1021/jm300212s
Homo sapiens TAR DNA-binding protein 43 Potency 28183.8 nM None
Homo sapiens THLE-2 IC50 30000.0 nM 10.1016/j.ejmech.2021.113740
Homo sapiens Thromboxane A2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Thromboxane-A synthase IC50 nan None None
Homo sapiens Thromboxane-A synthase Ki nan None None
Homo sapiens Type-1 angiotensin II receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Tyrosine-protein kinase FYN IC50 3890.0 nM None
Homo sapiens Tyrosine-protein kinase FYN Ki nan None None
Homo sapiens Tyrosine-protein kinase LCK IC50 nan None None
Homo sapiens Tyrosine-protein kinase LCK Ki nan None None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 2310.9 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 2592.9 nM None
Homo sapiens Vascular endothelial growth factor receptor 1 IC50 nan None None
Homo sapiens Vascular endothelial growth factor receptor 1 Ki nan None None
Homo sapiens Vascular endothelial growth factor receptor 2 Inhibition nan % 10.1021/jm200944b
Homo sapiens Vasoactive intestinal polypeptide receptor 1 IC50 nan None None
Homo sapiens Vasoactive intestinal polypeptide receptor 1 Ki nan None None
Homo sapiens Vasopressin V1a receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V1a receptor IC50 nan None None
Homo sapiens Vasopressin V1a receptor Ki nan None None
Homo sapiens Vasopressin V2 receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Homo sapiens Vasopressin V2 receptor IC50 794.33 nM 10.1021/jm301749y
Homo sapiens Vasopressin V2 receptor IC50 800.0 nM 10.1021/jm301749y
Homo sapiens Vasopressin V2 receptor IC50 6000.0 nM 10.1021/jm301749y
Homo sapiens Vasopressin V2 receptor IC50 6309.57 nM 10.1021/jm301749y
Homo sapiens Vasopressin V2 receptor IC50 11900.0 nM 10.1021/jm301749y
Homo sapiens Vasopressin V2 receptor IC50 12589.25 nM 10.1021/jm301749y
Homo sapiens Vasopressin V2 receptor Inhibition nan % 10.1021/jm301749y
Homo sapiens Voltage-gated N-type calcium channel alpha-1B subunit Inhibition nan % 10.1016/j.bmc.2016.11.007
Issatchenkia orientalis ATP binding cassette transporter Abc1p Activity nan None 10.1128/aac.01095-08
Issatchenkia orientalis ATP binding cassette transporter Abc1p FICI 0.104 None 10.1128/aac.01095-08
Issatchenkia orientalis ATP binding cassette transporter Abc1p FICI 0.298 None 10.1128/aac.01095-08
Klebsiella pneumoniae Klebsiella pneumoniae MIC 6.25 ug.mL-1 10.1016/j.ejmech.2019.111744
Klebsiella pneumoniae Klebsiella pneumoniae MIC 10000.0 nM 10.6019/CHEMBL4513141
Klebsiella pneumoniae Klebsiella pneumoniae MIC 20000.0 nM 10.6019/CHEMBL4513161
Kluyveromyces marxianus Kluyveromyces marxianus IC50 400.0 nM 10.1128/aac.00730-10
Kluyveromyces marxianus Kluyveromyces marxianus IZ 30.88 mm 10.1039/C0MD00074D
Kluyveromyces marxianus Kluyveromyces marxianus MIC 0.0625 ug.mL-1 10.1016/j.ejmech.2010.07.002
Kluyveromyces marxianus Kluyveromyces marxianus MIC 0.125 ug.mL-1 10.1039/C8MD00155C
Kluyveromyces marxianus Kluyveromyces marxianus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2015.04.047
Kluyveromyces marxianus Kluyveromyces marxianus MIC 0.25 ug.mL-1 10.1128/aac.01368-08
Kluyveromyces marxianus Kluyveromyces marxianus MIC 80.0 nM 10.1039/C0MD00074D
Kluyveromyces marxianus Kluyveromyces marxianus MIC 80.0 ug.mL-1 10.1021/jm00020a005
Kluyveromyces marxianus Kluyveromyces marxianus MIC 100.0 nM 10.1016/s0960-894x(00)00445-5
Kluyveromyces marxianus Kluyveromyces marxianus MIC 100.0 nM 10.1016/s0960-894x(00)00551-5
Kluyveromyces marxianus Kluyveromyces marxianus MIC50 0.02 ug.mL-1 10.1128/aac.01543-08
Kluyveromyces marxianus Kluyveromyces marxianus MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2011.06.008
Kluyveromyces marxianus Kluyveromyces marxianus MIC80 0.0625 ug.mL-1 10.1016/j.ejmech.2011.02.001
Kluyveromyces marxianus Kluyveromyces marxianus MIC80 0.0625 ug.mL-1 10.1039/C3MD20086H
Kluyveromyces marxianus Kluyveromyces marxianus MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2012.02.042
Kluyveromyces marxianus Kluyveromyces marxianus MIC90 0.06 ug.mL-1 10.1128/aac.01543-08
Leishmania amazonensis Leishmania amazonensis IC50 80.0 nM 10.1016/j.ejmech.2019.111660
Leishmania amazonensis Leishmania amazonensis IC50 440.0 nM 10.1016/j.ejmech.2019.111660
Leishmania donovani Leishmania donovani IC50 1420.0 nM 10.6019/CHEMBL3392926
Leishmania donovani Leishmania donovani IC50 2420.0 nM 10.6019/CHEMBL3392926
Leishmania major Leishmania major IC50 400.0 nM 10.1016/j.ejmech.2017.04.044
Leishmania major Leishmania major IC50 2000.0 nM 10.1016/j.ejmech.2017.04.044
Lichtheimia corymbifera Lichtheimia corymbifera Activity 100.0 % 10.1128/aac.00452-07
Lichtheimia corymbifera Lichtheimia corymbifera Activity nan None 10.1128/aac.00452-07
Lichtheimia corymbifera Lichtheimia corymbifera MFC 2.0 ug ml-1 10.1128/aac.00662-08
Lichtheimia corymbifera Lichtheimia corymbifera MIC 0.62 ug.mL-1 10.1128/aac.00184-09
Lichtheimia corymbifera Lichtheimia corymbifera MIC 0.62 ug.mL-1 10.1128/aac.01270-09
Lichtheimia corymbifera Lichtheimia corymbifera MIC 0.68 ug.mL-1 10.1128/aac.01467-08
Lichtheimia corymbifera Lichtheimia corymbifera MIC 1.03 ug.mL-1 10.1128/aac.01270-09
Lichtheimia corymbifera Lichtheimia corymbifera MIC 1.35 ug.mL-1 10.1128/aac.01467-08
Lichtheimia corymbifera Lichtheimia corymbifera MIC 2.5 ug.mL-1 10.1128/aac.00662-08
Lichtheimia corymbifera Lichtheimia corymbifera MIC50 1.0 ug.mL-1 10.1128/aac.01543-08
Lichtheimia corymbifera Lichtheimia corymbifera MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Lomentospora prolificans Lomentospora prolificans MFC 8.0 ug ml-1 10.1128/aac.00662-08
Lomentospora prolificans Lomentospora prolificans MIC 0.5 ug.mL-1 10.1128/aac.01388-07
Lomentospora prolificans Lomentospora prolificans MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Lomentospora prolificans Lomentospora prolificans MIC50 16.0 ug.mL-1 10.1128/aac.01388-07
Lomentospora prolificans Lomentospora prolificans MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Lomentospora prolificans Lomentospora prolificans MIC90 16.0 ug.mL-1 10.1128/aac.01388-07
Magnusiomyces capitatus Magnusiomyces capitatus MIC 0.06 ug.mL-1 10.1128/aac.00710-09
Magnusiomyces capitatus Magnusiomyces capitatus MIC50 0.25 ug.mL-1 10.1128/aac.01543-08
Magnusiomyces capitatus Magnusiomyces capitatus MIC90 0.5 ug.mL-1 10.1128/aac.01543-08
Meyerozyma guilliermondii Meyerozyma guilliermondii Activity 6.0 % 10.1128/aac.00323-08
Meyerozyma guilliermondii Meyerozyma guilliermondii Activity 88.0 % 10.1128/aac.00323-08
Meyerozyma guilliermondii Meyerozyma guilliermondii MFC 2.0 ug ml-1 10.1128/aac.00662-08
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC 0.03 ug.mL-1 10.1016/j.ejmech.2019.07.003
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC 0.12 ug.mL-1 10.1128/aac.00323-08
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC 0.15 ug.mL-1 10.1021/jm00020a005
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC 0.5 ug.mL-1 10.1016/j.ejmech.2010.10.019
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC 0.5 ug.mL-1 10.1128/aac.00231-10
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC 0.87 ug.mL-1 10.1128/aac.00662-08
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC 1.0 ug.mL-1 10.1128/aac.01368-08
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC50 0.25 ug.mL-1 10.1128/aac.01543-08
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC50 0.5 ug.mL-1 10.1128/aac.00231-10
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC50 0.5 ug.mL-1 10.1128/aac.00323-08
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC90 0.5 ug.mL-1 10.1128/aac.00323-08
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC90 1.0 ug.mL-1 10.1128/aac.00231-10
Meyerozyma guilliermondii Meyerozyma guilliermondii MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Microsporum Microsporum MIC 0.0625 ug.mL-1 10.1016/j.bmc.2012.04.045
Microsporum Microsporum MIC 2.633 ug.mL-1 10.1128/aac.01382-06
Microsporum Microsporum MIC50 4.0 ug.mL-1 10.1128/aac.01382-06
Microsporum Microsporum MIC80 0.0152 ug.mL-1 10.1016/j.ejmech.2007.01.006
Microsporum Microsporum MIC90 8.0 ug.mL-1 10.1128/aac.01382-06
Microsporum canis Microsporum canis IC50 2020.0 nM 10.1128/aac.00730-10
Microsporum canis Microsporum canis MIC 1.23 ug.mL-1 10.1128/aac.01382-06
Microsporum canis Microsporum canis MIC 16.0 ug.mL-1 10.1021/np1001412
Microsporum canis Microsporum canis MIC 80.0 ug.mL-1 10.1021/jm00020a005
Microsporum canis Microsporum canis MIC 100.0 nM 10.1016/s0960-894x(00)00445-5
Microsporum canis Microsporum canis MIC 100.0 nM 10.1016/s0960-894x(00)00551-5
Mucor Mucor Activity 57.0 % 10.1128/aac.00452-07
Mucor Mucor MFC 4.0 ug ml-1 10.1128/aac.00662-08
Mucor Mucor MIC 4.36 ug.mL-1 10.1128/aac.00662-08
Mucor Mucor MIC50 0.5 ug.mL-1 10.1128/aac.00452-07
Mucor Mucor MIC50 1.0 ug.mL-1 10.1128/aac.01539-06
Mucor Mucor MIC50 4.0 ug.mL-1 10.1128/aac.01539-06
Mucor Mucor MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Mucor Mucor MIC90 8.0 ug.mL-1 10.1128/aac.00452-07
Mucor Mucor MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Mucor Mucor MIC90 16.0 ug.mL-1 10.1128/aac.01539-06
Mucor circinelloides Mucor circinelloides Activity 0.0 % 10.1128/aac.00452-07
Mucor circinelloides Mucor circinelloides Activity nan None 10.1128/aac.00452-07
Mucor circinelloides Mucor circinelloides MIC 0.19 ug.mL-1 10.1016/j.ejmech.2020.112082
Mucor circinelloides Mucor circinelloides MIC 0.62 ug.mL-1 10.1128/aac.00184-09
Mucor circinelloides Mucor circinelloides MIC 11.89 ug.mL-1 10.1128/aac.01467-08
Mucor circinelloides Mucor circinelloides MIC 16.0 ug.mL-1 10.1128/aac.01467-08
Mucor hiemalis Mucor hiemalis MFC 8.0 ug ml-1 10.1128/aac.00662-08
Mucor hiemalis Mucor hiemalis MIC 1.0 ug.mL-1 10.1016/j.ejmech.2016.02.013
Mucor hiemalis Mucor hiemalis MIC 4.0 ug.mL-1 10.1039/C7MD00442G
Mucor hiemalis Mucor hiemalis MIC 16.0 ug.mL-1 10.1016/j.ejmech.2015.04.047
Mucor racemosus Mucor racemosus MIC50 1.0 ug.mL-1 10.1021/acs.jmedchem.2c00595
Mus musculus Brain Drug uptake 6.88 ug/g 10.1128/aac.01284-09
Mus musculus Mus musculus Activity nan None 10.1128/aac.00332-06
Mus musculus Mus musculus CFU 6.68 None 10.1016/S0960-894X(01)80556-4
Mus musculus Mus musculus CFU 8.87 None 10.1016/S0960-894X(01)80556-4
Mus musculus Mus musculus CFU 9.0 None 10.1016/S0960-894X(01)80556-4
Mus musculus Mus musculus CFU nan None 10.1016/S0960-894X(01)80556-4
Mus musculus Mus musculus ED50 2.6 mg.kg-1 10.1021/jm0494772
Mus musculus Mus musculus MIC 0.0078 None 10.1016/S0960-894X(01)80556-4
Mus musculus Mus musculus MIC 0.125 None 10.1016/S0960-894X(01)80556-4
Mus musculus Mus musculus No. of cures 3.0 None 10.1016/0960-894X(96)00363-0
Mus musculus Mus musculus No. of survivors 4.0 None 10.1016/0960-894X(96)00363-0
Mus musculus Mus musculus Protection nan None 10.1021/jm970726e
Mus musculus Mus musculus Protection nan None 10.1021/jm9707277
Mus musculus Mus musculus Survival 0.0 % 10.1016/0960-894X(94)00471-Q
Mus musculus Mus musculus Survival 0.0 % 10.1016/S0960-894X(01)80556-4
Mus musculus Mus musculus Survival 10.0 % 10.1016/0960-894X(94)00471-Q
Mus musculus Mus musculus Survival 10.0 % 10.1016/S0960-894X(01)80556-4
Mus musculus Mus musculus Survival 20.0 % 10.1016/0960-894X(94)00471-Q
Mus musculus Mus musculus Survival 20.0 % 10.1016/S0960-894X(01)80556-4
Mus musculus Mus musculus Survival 40.0 % 10.1016/0960-894X(94)00471-Q
Mus musculus Mus musculus Survival 60.0 % 10.1016/S0960-894X(01)80556-4
Mus musculus Nitric oxide synthase, inducible IC50 nan None None
Mus musculus Nitric oxide synthase, inducible Ki nan None None
Mus musculus P-glycoprotein 1 IC50 700.0 nM 10.1021/jm021012t
Mus musculus P-glycoprotein 3 Activity nan None 10.1128/aac.42.7.1738
Mus musculus P-glycoprotein 3 IC50 200.0 nM 10.1021/jm021012t
Mus musculus Serum Drug uptake 7.32 ug ml-1 10.1128/aac.01284-09
Naganishia albida Naganishia albida MIC 0.016 ug.mL-1 10.1128/aac.01384-07
Naganishia albida Naganishia albida MIC50 0.063 ug.mL-1 10.1128/aac.01384-07
Naganishia albida Naganishia albida MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Naganishia albida Naganishia albida MIC90 0.25 ug.mL-1 10.1128/aac.01384-07
Naganishia albida Naganishia albida MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Nakaseomyces glabratus Nakaseomyces glabratus Activity 0.0 % 10.1128/aac.00323-08
Nakaseomyces glabratus Nakaseomyces glabratus Activity 4.6 % 10.1128/aac.01475-07
Nakaseomyces glabratus Nakaseomyces glabratus Activity 37.0 % 10.1128/aac.00323-08
Nakaseomyces glabratus Nakaseomyces glabratus Activity 63.0 % 10.1128/aac.00323-08
Nakaseomyces glabratus Nakaseomyces glabratus Activity 72.7 % 10.1128/aac.01475-07
Nakaseomyces glabratus Nakaseomyces glabratus IC50 3740.0 nM 10.1128/aac.00730-10
Nakaseomyces glabratus Nakaseomyces glabratus IZ 16.0 mm 10.1128/aac.01510-06
Nakaseomyces glabratus Nakaseomyces glabratus IZ 30.0 mm 10.1128/aac.01510-06
Nakaseomyces glabratus Nakaseomyces glabratus MFC 4.0 ug ml-1 10.1128/aac.00662-08
Nakaseomyces glabratus Nakaseomyces glabratus MFC 256.0 ug ml-1 10.1016/j.ejmech.2013.10.051
Nakaseomyces glabratus Nakaseomyces glabratus MFC nan None None
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.007 ug.mL-1 10.1016/j.ejmech.2019.03.023
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.03 ug.mL-1 10.1016/j.bmcl.2013.01.039
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.03 ug.mL-1 10.1128/aac.01475-07
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.06 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2019.07.003
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2019.111689
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113740
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113955
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.125 ug.mL-1 10.1016/j.ejmech.2022.114195
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.125 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.19 ug.mL-1 10.1016/0960-894X(96)00363-0
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.25 ug.mL-1 10.1016/j.bmcl.2005.05.080
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2010.10.019
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2015.04.047
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.25 ug.mL-1 10.1016/j.ejmech.2022.114161
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.25 ug.mL-1 10.1021/np1001412
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.25 ug.mL-1 10.1128/aac.00323-08
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.25 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.5 ug.mL-1 10.1016/j.bmcl.2013.01.039
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.5 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.5 ug.mL-1 10.1128/aac.01364-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.5 ug.mL-1 10.1128/aac.01368-08
Nakaseomyces glabratus Nakaseomyces glabratus MIC 0.83 ug.mL-1 10.1128/aac.00662-08
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2008.10.055
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2009.02.036
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1.0 ug.mL-1 10.1016/j.bmcl.2013.01.039
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1.0 ug.mL-1 10.1016/j.ejmech.2019.07.003
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1.0 ug.mL-1 10.1016/s0960-894x(02)00020-3
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1.0 ug.mL-1 10.1039/C7MD00442G
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1.0 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1.0 ug.mL-1 10.1128/aac.01364-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1.15 ug.mL-1 10.1128/aac.00231-10
Nakaseomyces glabratus Nakaseomyces glabratus MIC 2.0 ug.mL-1 10.1016/j.bmcl.2013.01.039
Nakaseomyces glabratus Nakaseomyces glabratus MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.2c01497
Nakaseomyces glabratus Nakaseomyces glabratus MIC 2.0 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 2.0 ug.mL-1 10.1128/aac.01364-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 4.0 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 7.8 ug.mL-1 10.1016/j.bmc.2016.06.010
Nakaseomyces glabratus Nakaseomyces glabratus MIC 8.0 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 32.0 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC 64.0 ug.mL-1 10.1016/j.ejmech.2019.07.003
Nakaseomyces glabratus Nakaseomyces glabratus MIC 80.0 ug.mL-1 10.1021/jm00020a005
Nakaseomyces glabratus Nakaseomyces glabratus MIC 256.0 ug.mL-1 10.1016/j.bmcl.2013.03.078
Nakaseomyces glabratus Nakaseomyces glabratus MIC 256.0 ug.mL-1 10.1016/j.bmcl.2014.08.047
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1000.0 nM 10.1016/s0960-894x(00)00445-5
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1000.0 nM 10.1016/s0960-894x(00)00551-5
Nakaseomyces glabratus Nakaseomyces glabratus MIC 1800.0 ug.mL-1 10.1128/aac.01510-06
Nakaseomyces glabratus Nakaseomyces glabratus MIC 18700.0 ug.mL-1 10.1128/aac.01510-06
Nakaseomyces glabratus Nakaseomyces glabratus MIC nan None 10.1016/j.ejmech.2020.112046
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 0.03 ug.mL-1 10.1128/aac.01413-08
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 0.12 ug.mL-1 10.1128/aac.01475-07
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 0.25 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 0.25 ug.mL-1 10.1128/aac.01543-08
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 0.5 ug.mL-1 10.1128/aac.00231-10
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 0.5 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 0.5 ug.mL-1 10.1128/aac.01217-06
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 1.0 ug.mL-1 10.1128/aac.00323-08
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 1.0 ug.mL-1 10.1128/aac.00459-07
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 1.0 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 2.0 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 4.0 ug.mL-1 10.1128/aac.00459-07
Nakaseomyces glabratus Nakaseomyces glabratus MIC50 11100.0 nM 10.1016/j.ejmech.2017.03.075
Nakaseomyces glabratus Nakaseomyces glabratus MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2013.11.037
Nakaseomyces glabratus Nakaseomyces glabratus MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2014.01.009
Nakaseomyces glabratus Nakaseomyces glabratus MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2014.05.079
Nakaseomyces glabratus Nakaseomyces glabratus MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2017.10.043
Nakaseomyces glabratus Nakaseomyces glabratus MIC80 2.0 ug.mL-1 10.1021/np500024r
Nakaseomyces glabratus Nakaseomyces glabratus MIC90 0.12 ug.mL-1 10.1016/j.ejmech.2013.10.051
Nakaseomyces glabratus Nakaseomyces glabratus MIC90 0.5 ug.mL-1 10.1128/aac.01368-08
Nakaseomyces glabratus Nakaseomyces glabratus MIC90 0.5 ug.mL-1 10.1128/aac.01475-07
Nakaseomyces glabratus Nakaseomyces glabratus MIC90 1.0 ug.mL-1 10.1128/aac.00323-08
Nakaseomyces glabratus Nakaseomyces glabratus MIC90 1.0 ug.mL-1 10.1128/aac.01217-06
Nakaseomyces glabratus Nakaseomyces glabratus MIC90 1.0 ug.mL-1 10.1128/aac.01543-08
Nakaseomyces glabratus Nakaseomyces glabratus MIC90 2.0 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC90 8.0 ug.mL-1 10.1128/aac.01031-09
Nakaseomyces glabratus Nakaseomyces glabratus MIC90 16.0 ug.mL-1 10.1128/aac.00231-10
Nakaseomyces glabratus Nakaseomyces glabratus MIC90 16.0 ug.mL-1 10.1128/aac.01031-09
Nannizzia gypsea Nannizzia gypsea MIC 0.06 ug.mL-1 10.1016/j.ejmech.2020.112768
Nannizzia gypsea Nannizzia gypsea MIC 0.0625 ug.mL-1 10.1016/j.bmcl.2008.04.056
Nannizzia gypsea Nannizzia gypsea MIC 0.0625 ug.mL-1 10.1016/j.ejmech.2019.03.020
Nannizzia gypsea Nannizzia gypsea MIC 0.125 ug.mL-1 10.1016/j.bmcl.2013.03.098
Nannizzia gypsea Nannizzia gypsea MIC 0.25 ug.mL-1 10.1016/j.bmcl.2013.03.098
Nannizzia gypsea Nannizzia gypsea MIC 0.25 ug.mL-1 10.1021/np1001412
Nannizzia gypsea Nannizzia gypsea MIC 0.975 ug.mL-1 10.1021/np1001412
Nannizzia gypsea Nannizzia gypsea MIC 3.68 ug.mL-1 10.1128/aac.01382-06
Nannizzia gypsea Nannizzia gypsea MIC 80.0 ug.mL-1 10.1021/jm00020a005
Nannizzia gypsea Nannizzia gypsea MIC100 nan None 10.1016/j.ejmech.2009.09.024
Nannizzia gypsea Nannizzia gypsea MIC80 0.0152 ug.mL-1 10.1016/j.bmcl.2010.12.006
Nannizzia gypsea Nannizzia gypsea MIC80 0.0156 ug.mL-1 10.1016/j.ejmech.2011.02.042
Nannizzia gypsea Nannizzia gypsea MIC80 0.0156 ug.mL-1 10.1016/j.ejmech.2011.04.022
Nannizzia gypsea Nannizzia gypsea MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2009.01.048
Nannizzia gypsea Nannizzia gypsea MIC80 0.0625 ug.mL-1 10.1016/j.ejmech.2008.11.007
Nannizzia gypsea Nannizzia gypsea MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2009.07.144
Nannizzia gypsea Nannizzia gypsea MIC80 0.25 ug.mL-1 10.1016/j.ejmech.2009.05.018
Nannizzia gypsea Nannizzia gypsea MIC80 1.0 ug.mL-1 10.1016/j.bmcl.2013.11.037
Nannizzia gypsea Nannizzia gypsea MIC80 2.0 ug.mL-1 10.1016/j.ejmech.2014.05.079
Nannizzia gypsea Nannizzia gypsea MIC80 4.0 ug.mL-1 10.1016/j.ejmech.2014.01.009
Nannizzia gypsea Nannizzia gypsea MIC80 4.0 ug.mL-1 10.1016/j.ejmech.2017.10.043
Nannizzia gypsea Nannizzia gypsea MIC80 4.0 ug.mL-1 10.1021/np500024r
Neosartorya fumigata (Aspergillus fumigatus) 14-alpha sterol demethylase Kd 31.0 nM 10.1128/aac.00316-10
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSCA1100) (Aspergillus fumigatus) 14-alpha sterol demethylase Cyp51A Kd 1010.0 nM 10.1128/aac.00316-10
Oryctolagus cuniculus Angiotensin-converting enzyme IC50 nan None None
Oryctolagus cuniculus Angiotensin-converting enzyme Ki nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase IC50 nan None None
Oryctolagus cuniculus Arachidonate 15-lipoxygenase Ki nan None None
Paecilomyces variotii Paecilomyces variotii MIC 0.008 ug.mL-1 10.1128/aac.01475-07
Paecilomyces variotii Paecilomyces variotii MIC 0.06 ug.mL-1 10.1128/aac.00538-08
Paecilomyces variotii Paecilomyces variotii MIC50 0.06 ug.mL-1 10.1128/aac.01475-07
Paecilomyces variotii Paecilomyces variotii MIC50 0.06 ug.mL-1 10.1128/aac.01543-08
Paecilomyces variotii Paecilomyces variotii MIC90 0.25 ug.mL-1 10.1128/aac.01543-08
Paecilomyces variotii Paecilomyces variotii MIC90 16.0 ug.mL-1 10.1128/aac.01475-07
Papiliotrema laurentii Papiliotrema laurentii MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Papiliotrema laurentii Papiliotrema laurentii MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Paracoccidioides brasiliensis Paracoccidioides brasiliensis MIC 1.0 ug.mL-1 10.1016/j.bmcl.2020.127244
Paracoccidioides brasiliensis Paracoccidioides brasiliensis MIC 60.0 nM 10.1016/j.ejmech.2018.03.083
Paraphyton cookei Paraphyton cookei MIC 6.0 ug.mL-1 10.1128/aac.01382-06
Penicillium Penicillium MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Penicillium Penicillium MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Penicillium sp. Penicillium sp. MFC 2.0 ug ml-1 10.1128/aac.00662-08
Penicillium sp. Penicillium sp. MIC 0.008 ug.mL-1 10.1128/aac.01475-07
Penicillium sp. Penicillium sp. MIC 4.25 ug.mL-1 10.1128/aac.00662-08
Penicillium sp. Penicillium sp. MIC50 0.06 ug.mL-1 10.1128/aac.01475-07
Penicillium sp. Penicillium sp. MIC90 16.0 ug.mL-1 10.1128/aac.01475-07
Pichia fermentans Pichia fermentans MIC50 2.0 ug.mL-1 10.1128/aac.00459-07
Pichia kudriavzevii Pichia kudriavzevii Activity 0.0 % 10.1128/aac.00323-08
Pichia kudriavzevii Pichia kudriavzevii Activity 0.0 % 10.1128/aac.01475-07
Pichia kudriavzevii Pichia kudriavzevii Activity 10.0 % 10.1128/aac.00323-08
Pichia kudriavzevii Pichia kudriavzevii Activity 10.0 % 10.1128/aac.01475-07
Pichia kudriavzevii Pichia kudriavzevii Activity 90.0 % 10.1128/aac.00323-08
Pichia kudriavzevii Pichia kudriavzevii Activity nan None 10.1128/aac.01095-08
Pichia kudriavzevii Pichia kudriavzevii IC50 4210.0 nM 10.1128/aac.00730-10
Pichia kudriavzevii Pichia kudriavzevii IZ 30.34 mm 10.1039/C0MD00074D
Pichia kudriavzevii Pichia kudriavzevii MFC 0.12 ug ml-1 10.1016/j.ejmech.2013.10.051
Pichia kudriavzevii Pichia kudriavzevii MFC 0.5 ug ml-1 10.1128/aac.00662-08
Pichia kudriavzevii Pichia kudriavzevii MIC 0.007 ug.mL-1 10.1016/j.ejmech.2019.03.023
Pichia kudriavzevii Pichia kudriavzevii MIC 0.05 ug.mL-1 10.1016/0960-894X(96)00363-0
Pichia kudriavzevii Pichia kudriavzevii MIC 0.06 ug.mL-1 10.1016/j.ejmech.2010.10.019
Pichia kudriavzevii Pichia kudriavzevii MIC 0.06 ug.mL-1 10.1128/aac.01016-07
Pichia kudriavzevii Pichia kudriavzevii MIC 0.0625 ug.mL-1 10.1016/j.bmcl.2011.06.062
Pichia kudriavzevii Pichia kudriavzevii MIC 0.12 ug.mL-1 10.1016/j.ejmech.2009.09.024
Pichia kudriavzevii Pichia kudriavzevii MIC 0.12 ug.mL-1 10.1128/aac.01016-07
Pichia kudriavzevii Pichia kudriavzevii MIC 0.12 ug.mL-1 10.1128/aac.01368-08
Pichia kudriavzevii Pichia kudriavzevii MIC 0.12 ug.mL-1 10.1128/aac.01475-07
Pichia kudriavzevii Pichia kudriavzevii MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113715
Pichia kudriavzevii Pichia kudriavzevii MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113740
Pichia kudriavzevii Pichia kudriavzevii MIC 0.125 ug.mL-1 10.1016/j.ejmech.2021.113955
Pichia kudriavzevii Pichia kudriavzevii MIC 0.125 ug.mL-1 10.1016/j.ejmech.2022.114195
Pichia kudriavzevii Pichia kudriavzevii MIC 0.125 ug.mL-1 10.1128/aac.01031-09
Pichia kudriavzevii Pichia kudriavzevii MIC 0.125 ug.mL-1 10.1128/aac.01095-08
Pichia kudriavzevii Pichia kudriavzevii MIC 0.25 ug.mL-1 10.1016/j.ejmech.2009.11.045
Pichia kudriavzevii Pichia kudriavzevii MIC 0.25 ug.mL-1 10.1016/j.ejmech.2022.114161
Pichia kudriavzevii Pichia kudriavzevii MIC 0.25 ug.mL-1 10.1039/C7MD00442G
Pichia kudriavzevii Pichia kudriavzevii MIC 0.25 ug.mL-1 10.1128/aac.00323-08
Pichia kudriavzevii Pichia kudriavzevii MIC 0.25 ug.mL-1 10.1128/aac.01031-09
Pichia kudriavzevii Pichia kudriavzevii MIC 0.25 ug.mL-1 10.1128/aac.01095-08
Pichia kudriavzevii Pichia kudriavzevii MIC 0.33 ug.mL-1 10.1128/aac.00231-10
Pichia kudriavzevii Pichia kudriavzevii MIC 0.48 ug.mL-1 10.1016/j.bmc.2016.06.010
Pichia kudriavzevii Pichia kudriavzevii MIC 0.5 ug.mL-1 10.1016/j.bmcl.2008.10.055
Pichia kudriavzevii Pichia kudriavzevii MIC 0.5 ug.mL-1 10.1016/j.bmcl.2009.02.036
Pichia kudriavzevii Pichia kudriavzevii MIC 0.5 ug.mL-1 10.1021/np1001412
Pichia kudriavzevii Pichia kudriavzevii MIC 0.5 ug.mL-1 10.1128/aac.01031-09
Pichia kudriavzevii Pichia kudriavzevii MIC 0.5 ug.mL-1 10.1128/aac.01095-08
Pichia kudriavzevii Pichia kudriavzevii MIC 0.5 ug.mL-1 10.1128/aac.01176-06
Pichia kudriavzevii Pichia kudriavzevii MIC 1.0 ug.mL-1 10.1016/j.ejmech.2015.04.047
Pichia kudriavzevii Pichia kudriavzevii MIC 1.0 ug.mL-1 10.1021/acs.jmedchem.2c01497
Pichia kudriavzevii Pichia kudriavzevii MIC 1.0 ug.mL-1 10.1128/aac.01031-09
Pichia kudriavzevii Pichia kudriavzevii MIC 1.0 ug.mL-1 10.1128/aac.01095-08
Pichia kudriavzevii Pichia kudriavzevii MIC 1.0 ug.mL-1 10.1128/aac.01176-06
Pichia kudriavzevii Pichia kudriavzevii MIC 1.1 ug.mL-1 10.1128/aac.00662-08
Pichia kudriavzevii Pichia kudriavzevii MIC 1.25 ug.mL-1 10.1021/jm00020a005
Pichia kudriavzevii Pichia kudriavzevii MIC 2.0 ug.mL-1 10.1021/acs.jmedchem.2c01497
Pichia kudriavzevii Pichia kudriavzevii MIC 2.0 ug.mL-1 10.1128/aac.01095-08
Pichia kudriavzevii Pichia kudriavzevii MIC 16.0 ug.mL-1 10.1128/aac.01031-09
Pichia kudriavzevii Pichia kudriavzevii MIC 180.0 nM 10.1016/j.ejmech.2018.03.083
Pichia kudriavzevii Pichia kudriavzevii MIC 700.0 nM 10.1039/C0MD00074D
Pichia kudriavzevii Pichia kudriavzevii MIC 1000.0 nM 10.1016/s0960-894x(00)00445-5
Pichia kudriavzevii Pichia kudriavzevii MIC 1000.0 nM 10.1016/s0960-894x(00)00551-5
Pichia kudriavzevii Pichia kudriavzevii MIC nan None 10.1016/j.ejmech.2020.112046
Pichia kudriavzevii Pichia kudriavzevii MIC50 0.03 ug.mL-1 10.1128/aac.01413-08
Pichia kudriavzevii Pichia kudriavzevii MIC50 0.12 ug.mL-1 10.1128/aac.01413-08
Pichia kudriavzevii Pichia kudriavzevii MIC50 0.25 ug.mL-1 10.1128/aac.00231-10
Pichia kudriavzevii Pichia kudriavzevii MIC50 0.25 ug.mL-1 10.1128/aac.01543-08
Pichia kudriavzevii Pichia kudriavzevii MIC50 0.5 ug.mL-1 10.1128/aac.00323-08
Pichia kudriavzevii Pichia kudriavzevii MIC50 0.5 ug.mL-1 10.1128/aac.00459-07
Pichia kudriavzevii Pichia kudriavzevii MIC50 0.5 ug.mL-1 10.1128/aac.01031-09
Pichia kudriavzevii Pichia kudriavzevii MIC50 0.5 ug.mL-1 10.1128/aac.01217-06
Pichia kudriavzevii Pichia kudriavzevii MIC50 0.5 ug.mL-1 10.1128/aac.01475-07
Pichia kudriavzevii Pichia kudriavzevii MIC50 1.0 ug.mL-1 10.1128/aac.00459-07
Pichia kudriavzevii Pichia kudriavzevii MIC50 680.0 nM 10.1016/j.ejmech.2017.03.075
Pichia kudriavzevii Pichia kudriavzevii MIC50 nan None 10.1128/aac.01031-09
Pichia kudriavzevii Pichia kudriavzevii MIC80 0.25 ug.mL-1 10.1016/j.bmcl.2010.03.014
Pichia kudriavzevii Pichia kudriavzevii MIC80 0.5 ug.mL-1 10.1016/j.bmcl.2009.01.048
Pichia kudriavzevii Pichia kudriavzevii MIC80 0.5 ug.mL-1 10.1016/j.ejmech.2008.11.007
Pichia kudriavzevii Pichia kudriavzevii MIC80 1.0 ug.mL-1 10.1016/j.ejmech.2012.04.013
Pichia kudriavzevii Pichia kudriavzevii MIC90 0.12 ug.mL-1 10.1128/aac.01368-08
Pichia kudriavzevii Pichia kudriavzevii MIC90 0.25 ug.mL-1 10.1128/aac.01543-08
Pichia kudriavzevii Pichia kudriavzevii MIC90 0.5 ug.mL-1 10.1016/j.ejmech.2013.06.018
Pichia kudriavzevii Pichia kudriavzevii MIC90 0.5 ug.mL-1 10.1128/aac.00231-10
Pichia kudriavzevii Pichia kudriavzevii MIC90 0.5 ug.mL-1 10.1128/aac.00323-08
Pichia kudriavzevii Pichia kudriavzevii MIC90 0.5 ug.mL-1 10.1128/aac.01217-06
Pichia kudriavzevii Pichia kudriavzevii MIC90 0.5 ug.mL-1 10.1128/aac.01475-07
Pichia kudriavzevii Pichia kudriavzevii MIC90 0.6 ug.mL-1 10.1016/j.ejmech.2013.10.051
Pichia kudriavzevii Pichia kudriavzevii MIC90 16.0 ug.mL-1 10.1128/aac.01031-09
Pichia kudriavzevii Pichia kudriavzevii MIC90 nan None 10.1128/aac.01031-09
Pichia norvegensis Pichia norvegensis MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
Pichia norvegensis Pichia norvegensis MIC50 1.0 ug.mL-1 10.1128/aac.00459-07
Pichia norvegensis Pichia norvegensis MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Plasmodium falciparum Plasmodium falciparum AbsAC35 3.81 uM None
Plasmodium falciparum Plasmodium falciparum AbsAC35 4.24 uM None
Plasmodium falciparum Plasmodium falciparum IC50 1370.0 nM 10.6019/CHEMBL3392926
Plasmodium falciparum Plasmodium falciparum Potency 3380.8 nM None
Plasmodium falciparum 3D7 HSP40, subfamily A, putative AbsAC1000_uM 0.129 uM None
Plasmodium falciparum 3D7 HSP90 AC50 195.0 nM None
Proteus mirabilis Proteus mirabilis MIC 6.25 ug.mL-1 10.1016/j.ejmech.2019.111744
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 6.25 ug.mL-1 10.1016/j.ejmech.2019.111744
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 10000.0 nM 10.6019/CHEMBL4513141
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC 20000.0 nM 10.6019/CHEMBL4513161
Pseudomonas aeruginosa Pseudomonas aeruginosa MIC nan None 10.1016/j.bmcl.2015.10.028
Rattus norvegicus Aldose reductase IC50 nan None None
Rattus norvegicus Aldose reductase Ki nan None None
Rattus norvegicus Alpha-1a adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1a adrenergic receptor Ki nan None None
Rattus norvegicus Alpha-1b adrenergic receptor IC50 nan None None
Rattus norvegicus Alpha-1b adrenergic receptor Ki nan None None
Rattus norvegicus Androgen Receptor AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Androgen Receptor IC50 nan None None
Rattus norvegicus Androgen Receptor Ki nan None None
Rattus norvegicus Cyclooxygenase-1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus GABA receptor alpha-1 subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glutamate (NMDA) receptor subunit zeta 1 AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Glycine receptor IC50 nan None None
Rattus norvegicus Glycine receptor Ki nan None None
Rattus norvegicus Insulin receptor IC50 nan None None
Rattus norvegicus Insulin receptor Ki nan None None
Rattus norvegicus Nitric-oxide synthase, brain IC50 nan None None
Rattus norvegicus Nitric-oxide synthase, brain Ki nan None None
Rattus norvegicus Peripheral myelin protein 22 Potency 3219.7 nM None
Rattus norvegicus Peripheral myelin protein 22 Potency 12579.7 nM None
Rattus norvegicus Plasma Fu 0.002 None 10.1021/jm901371v
Rattus norvegicus Rattus norvegicus ALB 39000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 39700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 40000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 40300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 41700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALB 42300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 284.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 347.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 402.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 472.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 522.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALP 535.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 52.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 56.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 57.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 59.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 76.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ALT 78.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 71.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 74.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 77.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 81.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 84.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AST 97.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus AUC 27.5 ng.hr.mL-1 10.1016/j.bmcl.2011.06.062
Rattus norvegicus Rattus norvegicus AUC 343.0 ng.hr.mL-1 10.1016/j.bmcl.2011.06.062
Rattus norvegicus Rattus norvegicus BASO 0.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BASOLE 0.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 1.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BILI 2.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 90.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 106.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 110.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 143.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus BUN 160.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 99.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 100.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 102.33 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 102.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHLORIDE 103.67 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 503.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 560.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 670.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 686.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CHOL 748.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 199.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 230.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 240.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 448.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 522.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CK 659.17 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CL 321.67 mL.min-1.kg-1 10.1016/j.bmcl.2011.06.062
Rattus norvegicus Rattus norvegicus Cmax 8.9 nM 10.1016/j.bmcl.2011.06.062
Rattus norvegicus Rattus norvegicus CO2 22330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 22670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 23670000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 25330000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CO2 25500000.0 nM 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 1.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 2.1 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 3.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus CREAT 3.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus ED50 1.7 umol.kg-1 10.1016/s0960-894x(02)00892-2
Rattus norvegicus Rattus norvegicus ED50 2.5 umol.kg-1 10.1016/s0960-894x(02)00892-2
Rattus norvegicus Rattus norvegicus ED50 4.7 umol.kg-1 10.1016/s0960-894x(02)00892-2
Rattus norvegicus Rattus norvegicus ED50 7.2 umol.kg-1 10.1016/s0960-894x(02)00892-2
Rattus norvegicus Rattus norvegicus ED50 8.9 umol.kg-1 10.1016/s0960-894x(02)00892-2
Rattus norvegicus Rattus norvegicus EOS 60.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 104.17 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 139.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 143.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 154.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOS 331.5 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 0.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 1.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 1.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus EOSLE 1.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus F 8.0 % 10.1016/j.bmcl.2011.06.062
Rattus norvegicus Rattus norvegicus GLUC 1606.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1626.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1641.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1650.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1810.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus GLUC 1843.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.22 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 33.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 36.73 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 37.97 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 38.27 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HCT 38.43 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 132000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 133800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 141300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 144300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 145700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus HGB 146700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 54.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 92.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 106.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 126.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 271.5 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LDH 290.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 6.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 6.83 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 9.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 10.0 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 11.67 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LIPASE 17.33 U.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 9936.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 10102.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 10619.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 12564.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 14547.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYM 15021.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 79.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 84.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 87.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus LYMLE 89.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.0 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.2 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.23 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 24.4 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 25.05 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCH 25.17 pg 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 377700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 381700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 384000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 384700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 397300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCHC 397800.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.6 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 62.97 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.38 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 63.43 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MCV 64.1 fL 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 160.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 292.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 376.5 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 425.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 467.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONO 609.67 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 1.83 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 2.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 3.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 3.67 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus MONOLE 5.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 5.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 6.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 8.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 9.33 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 10.0 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTLE 16.5 % 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 634.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 825.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 876.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1115.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 1640.17 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus NEUTSG 3070.33 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 106.3 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 106.5 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 115.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 117.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 117.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PHOS 128.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1142670.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1165330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1189330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1209330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1274500.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PLAT 1278330.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.88 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 5.95 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.01 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.28 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.35 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus POTASSIUM 6.49 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 55500.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 57200.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 58300.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 58700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 59700.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus PROT 64000.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5240000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5350000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5790000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 5970000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBC 6060000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus RBCNUC 0.0 /100WBC 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 139.5 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 139.65 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 141.73 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.3 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 142.93 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus SODIUM 143.47 mEq.L-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus T1/2 2.57 hr 10.1016/j.bmcl.2011.06.062
Rattus norvegicus Rattus norvegicus T1/2 22.0 hr 10.1016/j.bmcl.2011.06.062
Rattus norvegicus Rattus norvegicus Tissue Severity Score nan None 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus Tmax 3.0 hr 10.1016/j.bmcl.2011.06.062
Rattus norvegicus Rattus norvegicus URATE 11.2 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 13.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 16.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 17.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 19.7 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus URATE 20.0 ug.mL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 11030.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 11830.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 11970.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 14000.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 16580.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Rattus norvegicus WBC 18800.0 cells.uL-1 10.6019/CHEMBL3885881
Rattus norvegicus Serotonin 1a (5-HT1a) receptor IC50 nan None None
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Ki nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor IC50 nan None None
Rattus norvegicus Serotonin 1b (5-HT1b) receptor Ki nan None None
Rattus norvegicus Transient receptor potential cation channel subfamily M member 8 Inhibition nan % 10.1016/j.bmc.2016.11.007
Rattus norvegicus Vanilloid receptor Inhibition nan % 10.1016/j.bmc.2016.11.007
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit AC50 30000.0 nM 10.1038/s41467-023-40064-9
Rattus norvegicus Voltage-gated L-type calcium channel alpha-1C subunit IC50 nan None None
Rattus norvegicus Voltage-gated N-type calcium channel alpha-1B subunit AC50 10000.0 nM 10.1038/s41467-023-40064-9
Rhizomucor Rhizomucor Activity 67.0 % 10.1128/aac.00452-07
Rhizomucor Rhizomucor Activity nan None 10.1128/aac.00452-07
Rhizomucor Rhizomucor MFC 2.0 ug ml-1 10.1128/aac.00662-08
Rhizomucor Rhizomucor MIC50 2.0 ug.mL-1 10.1128/aac.01539-06
Rhizomucor Rhizomucor MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Rhizomucor Rhizomucor MIC50 16.0 ug.mL-1 10.1128/aac.01539-06
Rhizomucor Rhizomucor MIC90 2.0 ug.mL-1 10.1128/aac.01539-06
Rhizomucor Rhizomucor MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Rhizomucor Rhizomucor MIC90 16.0 ug.mL-1 10.1128/aac.01539-06
Rhizopus Rhizopus Activity 62.0 % 10.1128/aac.00452-07
Rhizopus Rhizopus MFC 4.0 ug ml-1 10.1128/aac.00662-08
Rhizopus Rhizopus MIC50 0.5 ug.mL-1 10.1128/aac.00452-07
Rhizopus Rhizopus MIC50 1.0 ug.mL-1 10.1128/aac.01539-06
Rhizopus Rhizopus MIC50 4.0 ug.mL-1 10.1128/aac.01539-06
Rhizopus Rhizopus MIC90 4.0 ug.mL-1 10.1128/aac.00452-07
Rhizopus Rhizopus MIC90 16.0 ug.mL-1 10.1128/aac.01539-06
Rhizopus arrhizus Rhizopus arrhizus Activity 50.0 % 10.1128/aac.00452-07
Rhizopus arrhizus Rhizopus arrhizus MFC 8.0 ug ml-1 10.1128/aac.00662-08
Rhizopus arrhizus Rhizopus arrhizus MIC 0.19 ug.mL-1 10.1016/j.ejmech.2020.112082
Rhizopus arrhizus Rhizopus arrhizus MIC 0.5 ug.mL-1 10.1016/j.ejmech.2016.02.013
Rhizopus arrhizus Rhizopus arrhizus MIC 0.62 ug.mL-1 10.1128/aac.00184-09
Rhizopus arrhizus Rhizopus arrhizus MIC 1.0 ug.mL-1 10.1039/C7MD00442G
Rhizopus arrhizus Rhizopus arrhizus MIC 1.125 ug.mL-1 10.1016/j.ejmech.2020.112082
Rhizopus arrhizus Rhizopus arrhizus MIC 4.0 ug.mL-1 10.1128/aac.00662-08
Rhizopus arrhizus Rhizopus arrhizus MIC 4.0 ug.mL-1 10.1128/aac.01467-08
Rhizopus arrhizus Rhizopus arrhizus MIC 6.96 ug.mL-1 10.1128/aac.01467-08
Rhizopus arrhizus Rhizopus arrhizus MIC 16.0 ug.mL-1 10.1016/j.ejmech.2015.04.047
Rhizopus arrhizus Rhizopus arrhizus MIC50 0.5 ug.mL-1 10.1128/aac.00452-07
Rhizopus arrhizus Rhizopus arrhizus MIC50 4.0 ug.mL-1 10.1128/aac.01543-08
Rhizopus arrhizus Rhizopus arrhizus MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Rhizopus microsporus var. microsporus Rhizopus microsporus var. microsporus Activity 0.0 % 10.1128/aac.00452-07
Rhizopus microsporus var. microsporus Rhizopus microsporus var. microsporus Activity nan None 10.1128/aac.00452-07
Rhizopus microsporus var. rhizopodiformis Rhizopus microsporus var. rhizopodiformis Activity 60.0 % 10.1128/aac.00452-07
Rhizopus microsporus var. rhizopodiformis Rhizopus microsporus var. rhizopodiformis MIC50 0.5 ug.mL-1 10.1128/aac.00452-07
Rhodotorula Rhodotorula MIC50 0.06 ug.mL-1 10.1128/aac.00459-07
Rhodotorula glutinis Rhodotorula glutinis MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Rhodotorula glutinis Rhodotorula glutinis MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Rhodotorula mucilaginosa Rhodotorula mucilaginosa MIC 80.0 ug.mL-1 10.1021/jm00020a005
Rhodotorula mucilaginosa Rhodotorula mucilaginosa MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Rhodotorula mucilaginosa Rhodotorula mucilaginosa MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 0.035 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 0.036 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 0.039 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 0.042 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 0.044 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 0.136 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 0.164 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 0.166 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 0.17 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 0.176 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 5.0 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 6.0 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 24.0 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 42.0 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity 52.0 % 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Activity nan None 10.1016/j.ejmech.2011.10.053
Saccharomyces cerevisiae Saccharomyces cerevisiae FC 1.5 None 10.1016/j.ejmech.2011.10.053
Saccharomyces cerevisiae Saccharomyces cerevisiae GI nan None 10.1016/j.bmcl.2012.03.006
Saccharomyces cerevisiae Saccharomyces cerevisiae GI nan None 10.1016/j.ejmech.2011.10.053
Saccharomyces cerevisiae Saccharomyces cerevisiae Inhibition 95.0 % 10.1016/j.ejmech.2011.10.053
Saccharomyces cerevisiae Saccharomyces cerevisiae IZ 0.0 mm 10.1016/j.ejmech.2010.07.050
Saccharomyces cerevisiae Saccharomyces cerevisiae IZ 11.0 mm 10.1016/j.ejmech.2010.07.050
Saccharomyces cerevisiae Saccharomyces cerevisiae IZ 30.0 mm 10.1016/j.ejmech.2011.11.035
Saccharomyces cerevisiae Saccharomyces cerevisiae MFC 4.0 ug ml-1 10.1128/aac.00662-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 0.031 ug.mL-1 10.1128/aac.00349-10
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 0.031 ug.mL-1 10.1128/aac.01095-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 0.063 ug.mL-1 10.1128/aac.01095-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 0.125 ug.mL-1 10.1128/aac.00349-10
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 0.125 ug.mL-1 10.1128/aac.01095-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 0.25 ug.mL-1 10.1128/aac.01095-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 0.5 ug.mL-1 10.1128/aac.01031-09
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 1.0 ug.mL-1 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 2.0 ug.mL-1 10.1128/aac.00662-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 2.0 ug.mL-1 10.1128/aac.01095-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 4.0 ug.mL-1 10.1128/aac.01031-09
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 4.0 ug.mL-1 10.1128/aac.01095-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 8.0 ug.mL-1 10.1128/aac.01095-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 128.0 ug.mL-1 10.1128/aac.00517-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC 128.0 ug.mL-1 10.1128/aac.01095-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC50 2.0 ug.mL-1 10.1128/aac.00459-07
Saccharomyces cerevisiae Saccharomyces cerevisiae MIC90 2.0 ug.mL-1 10.1128/aac.01543-08
Saccharomyces cerevisiae Saccharomyces cerevisiae Potency 12589.3 nM None
Saccharomycopsis Saccharomycopsis MIC50 0.5 ug.mL-1 10.1128/aac.00459-07
Salmonella enterica subsp. enterica serovar Typhimurium Salmonella typhimurium MIC nan None 10.1016/j.bmcl.2015.10.028
Scedosporium apiospermum Scedosporium apiospermum MFC 4.0 ug ml-1 10.1128/aac.00662-08
Scedosporium apiospermum Scedosporium apiospermum MIC 0.125 ug.mL-1 10.1128/aac.01388-07
Scedosporium apiospermum Scedosporium apiospermum MIC 0.5 ug.mL-1 10.1016/j.ejmech.2020.112082
Scedosporium apiospermum Scedosporium apiospermum MIC 2.66 ug.mL-1 10.1128/aac.00662-08
Scedosporium apiospermum Scedosporium apiospermum MIC50 0.5 ug.mL-1 10.1128/aac.01388-07
Scedosporium apiospermum Scedosporium apiospermum MIC50 1.0 ug.mL-1 10.1128/aac.01543-08
Scedosporium apiospermum Scedosporium apiospermum MIC90 2.0 ug.mL-1 10.1128/aac.01388-07
Scedosporium apiospermum Scedosporium apiospermum MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Scedosporium boydii Scedosporium boydii MIC 0.25 ug.mL-1 10.1128/aac.01177-06
Scopulariopsis brevicaulis Scopulariopsis brevicaulis MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Scopulariopsis brevicaulis Scopulariopsis brevicaulis MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 2.535 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 12.23 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score 0.05218 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 100000.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -4.93 % 10.21203/rs.3.rs-23951/v1
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -0.12 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 8.0 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition index 0.5215 None 10.1101/2020.04.03.023846
Sporothrix Sporothrix MIC 0.5 ug.mL-1 10.1128/aac.01012-07
Sporothrix Sporothrix MIC 32.0 ug.mL-1 10.1128/aac.01012-07
Sporothrix Sporothrix MIC 125.0 nM 10.1016/j.ejmech.2020.112962
Sporothrix Sporothrix MIC50 0.5 ug.mL-1 10.1128/aac.01012-07
Sporothrix Sporothrix MIC90 1.0 ug.mL-1 10.1128/aac.01012-07
Sporothrix albicans Sporothrix albicans MIC 32.0 ug.mL-1 10.1128/aac.01012-07
Sporothrix albicans Sporothrix albicans MIC50 32.0 ug.mL-1 10.1128/aac.01012-07
Sporothrix albicans Sporothrix albicans MIC90 32.0 ug.mL-1 10.1128/aac.01012-07
Sporothrix globosa Sporothrix globosa MIC 1.0 ug.mL-1 10.1128/aac.01012-07
Sporothrix globosa Sporothrix globosa MIC50 32.0 ug.mL-1 10.1128/aac.01012-07
Sporothrix globosa Sporothrix globosa MIC90 32.0 ug.mL-1 10.1128/aac.01012-07
Sporothrix schenckii Sporothrix schenckii MFC 0.5 ug ml-1 10.1128/aac.00662-08
Sporothrix schenckii Sporothrix schenckii MIC 0.06 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC 0.12 ug.mL-1 10.1128/aac.00662-08
Sporothrix schenckii Sporothrix schenckii MIC 0.13 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC 0.25 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC 0.5 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC 1.0 ug.mL-1 10.1128/aac.01012-07
Sporothrix schenckii Sporothrix schenckii MIC 1.0 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC 2.0 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC 4.0 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC 8.0 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC 125.0 nM 10.1016/j.ejmech.2020.112962
Sporothrix schenckii Sporothrix schenckii MIC 10000.0 nM 10.1016/s0960-894x(00)00445-5
Sporothrix schenckii Sporothrix schenckii MIC 10000.0 nM 10.1016/s0960-894x(00)00551-5
Sporothrix schenckii Sporothrix schenckii MIC50 0.25 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC50 0.5 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC50 1.0 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC50 4.0 ug.mL-1 10.1128/aac.01012-07
Sporothrix schenckii Sporothrix schenckii MIC90 0.25 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC90 0.5 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC90 2.0 ug.mL-1 10.1128/aac.01176-06
Sporothrix schenckii Sporothrix schenckii MIC90 32.0 ug.mL-1 10.1128/aac.01012-07
Staphylococcus aureus Staphylococcus aureus MIC 10000.0 nM 10.6019/CHEMBL4513141
Staphylococcus aureus Staphylococcus aureus MIC 20000.0 nM 10.6019/CHEMBL4513161
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1016/j.bmcl.2015.10.028
Staphylococcus aureus Staphylococcus aureus MIC nan None 10.1016/j.bmcl.2019.02.033
Starmerella stellata Starmerella stellata MIC50 2.0 ug.mL-1 10.1128/aac.00459-07
Streptococcus mutans Streptococcus mutans MIC nan None 10.1016/j.bmcl.2015.10.028
Streptococcus mutans Streptococcus mutans MIC nan None 10.1016/j.bmcl.2019.02.033
Syncephalastrum Syncephalastrum MIC50 1.0 ug.mL-1 10.1128/aac.01539-06
Syncephalastrum Syncephalastrum MIC90 1.0 ug.mL-1 10.1128/aac.01539-06
Syncephalastrum Syncephalastrum MIC90 8.0 ug.mL-1 10.1128/aac.01539-06
Syncephalastrum racemosum Syncephalastrum racemosum IZ 22.0 mm 10.1016/j.ejmech.2011.07.035
Syncephalastrum racemosum Syncephalastrum racemosum IZ 22.0 mm 10.1016/j.ejmech.2011.08.018
Syncephalastrum racemosum Syncephalastrum racemosum IZ 23.9 mm 10.1016/j.ejmech.2016.11.019
Talaromyces marneffei Talaromyces marneffei IZ 22.0 mm 10.1016/j.ejmech.2012.02.030
Talaromyces marneffei Talaromyces marneffei IZ 25.0 mm 10.1007/s00044-012-0154-3
Talaromyces marneffei Talaromyces marneffei MFC 0.25 ug ml-1 10.1128/aac.00662-08
Talaromyces marneffei Talaromyces marneffei MIC 0.008 ug.mL-1 10.1128/aac.01475-07
Talaromyces marneffei Talaromyces marneffei MIC 0.25 ug.mL-1 10.1128/aac.00662-08
Talaromyces marneffei Talaromyces marneffei MIC 6.25 ug.mL-1 10.1007/s00044-012-0154-3
Talaromyces marneffei Talaromyces marneffei MIC 6.25 ug.mL-1 10.1016/j.ejmech.2019.03.023
Talaromyces marneffei Talaromyces marneffei MIC 2210.0 nM 10.1016/j.ejmech.2012.02.030
Talaromyces marneffei Talaromyces marneffei MIC 16000.0 ug.mL-1 10.1016/j.ejmech.2006.09.010
Talaromyces marneffei Talaromyces marneffei MIC50 0.06 ug.mL-1 10.1128/aac.01475-07
Talaromyces marneffei Talaromyces marneffei MIC90 16.0 ug.mL-1 10.1128/aac.01475-07
Toxoplasma gondii Toxoplasma gondii IC50 500.0 nM 10.1021/acs.jmedchem.1c01569
Toxoplasma gondii Toxoplasma gondii Survival 40.0 % 10.1021/acs.jmedchem.1c01569
Trichoderma Trichoderma MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
Trichoderma Trichoderma MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Trichophyton Trichophyton MIC 1.993 ug.mL-1 10.1128/aac.01382-06
Trichophyton Trichophyton MIC50 2.0 ug.mL-1 10.1128/aac.01382-06
Trichophyton Trichophyton MIC90 4.0 ug.mL-1 10.1128/aac.01382-06
Trichophyton benhamiae Trichophyton benhamiae MIC 80.0 ug.mL-1 10.1021/jm00020a005
Trichophyton benhamiae Trichophyton benhamiae MIC 100.0 nM 10.1016/s0960-894x(00)00445-5
Trichophyton benhamiae Trichophyton benhamiae MIC 100.0 nM 10.1016/s0960-894x(00)00551-5
Trichophyton benhamiae Trichophyton benhamiae MIC 16000.0 ug.mL-1 10.1016/j.ejmech.2006.09.010
Trichophyton benhamiae Trichophyton benhamiae MIC50 0.01 ug.mL-1 10.1021/jm0494772
Trichophyton benhamiae Trichophyton benhamiae MIC90 0.1288 ug.mL-1 10.1021/jm0494772
Trichophyton erinacei Trichophyton erinacei MIC100 nan None 10.1016/j.ejmech.2009.09.024
Trichophyton interdigitale Trichophyton interdigitale MIC 0.095 ug.mL-1 10.1016/j.ejmech.2020.112768
Trichophyton mentagrophytes Trichophyton mentagrophytes IC50 370.0 nM 10.1128/aac.00730-10
Trichophyton mentagrophytes Trichophyton mentagrophytes IZ 23.0 mm 10.1007/s00044-012-0154-3
Trichophyton mentagrophytes Trichophyton mentagrophytes IZ 30.0 mm 10.1016/j.ejmech.2012.02.030
Trichophyton mentagrophytes Trichophyton mentagrophytes MFC nan None None
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC 0.5 ug.mL-1 10.1021/np1001412
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC 1.682 ug.mL-1 10.1128/aac.01382-06
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC 2.0 ug.mL-1 10.1021/np1001412
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC 6.25 ug.mL-1 10.1007/s00044-012-0154-3
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC 6.25 ug.mL-1 10.1016/j.ejmech.2019.03.023
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC 8860.0 nM 10.1016/j.ejmech.2012.02.030
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC nan None 10.1016/j.ejmech.2010.06.029
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC50 2.0 ug.mL-1 10.1128/aac.01382-06
Trichophyton mentagrophytes Trichophyton mentagrophytes MIC90 4.0 ug.mL-1 10.1128/aac.01382-06
Trichophyton quinckeanum Trichophyton quinckeanum IC50 2930.0 nM 10.1128/aac.00730-10
Trichophyton rubrum Trichophyton rubrum IC50 560.0 nM 10.1128/aac.00730-10
Trichophyton rubrum Trichophyton rubrum IC50 980.0 nM 10.1128/aac.00730-10
Trichophyton rubrum Trichophyton rubrum MFC nan None None
Trichophyton rubrum Trichophyton rubrum MIC 0.0156 ug.mL-1 10.1016/j.bmcl.2008.04.056
Trichophyton rubrum Trichophyton rubrum MIC 0.03 ug.mL-1 10.1021/np500080m
Trichophyton rubrum Trichophyton rubrum MIC 0.06 ug.mL-1 10.1016/j.ejmech.2020.112768
Trichophyton rubrum Trichophyton rubrum MIC 0.0625 ug.mL-1 10.1016/j.bmc.2012.04.045
Trichophyton rubrum Trichophyton rubrum MIC 0.0625 ug.mL-1 10.1016/j.ejmech.2010.07.002
Trichophyton rubrum Trichophyton rubrum MIC 0.0625 ug.mL-1 10.1016/j.ejmech.2019.03.020
Trichophyton rubrum Trichophyton rubrum MIC 0.125 ug.mL-1 10.1021/np1001412
Trichophyton rubrum Trichophyton rubrum MIC 0.25 ug.mL-1 10.1021/np4001703
Trichophyton rubrum Trichophyton rubrum MIC 0.5 ug.mL-1 10.1021/np1001412
Trichophyton rubrum Trichophyton rubrum MIC 0.63 ug.mL-1 10.1021/jm00020a005
Trichophyton rubrum Trichophyton rubrum MIC 1.955 ug.mL-1 10.1128/aac.01382-06
Trichophyton rubrum Trichophyton rubrum MIC 100.0 nM 10.1016/s0960-894x(00)00445-5
Trichophyton rubrum Trichophyton rubrum MIC 100.0 nM 10.1016/s0960-894x(00)00551-5
Trichophyton rubrum Trichophyton rubrum MIC nan None 10.1016/j.ejmech.2010.06.029
Trichophyton rubrum Trichophyton rubrum MIC50 0.01 ug.mL-1 10.1021/jm0494772
Trichophyton rubrum Trichophyton rubrum MIC50 0.062 ug.mL-1 10.1016/j.bmcl.2014.05.068
Trichophyton rubrum Trichophyton rubrum MIC50 2.0 ug.mL-1 10.1128/aac.01382-06
Trichophyton rubrum Trichophyton rubrum MIC80 0.004 ug.mL-1 10.1016/j.bmcl.2010.03.014
Trichophyton rubrum Trichophyton rubrum MIC80 0.0152 ug.mL-1 10.1016/j.bmcl.2010.12.006
Trichophyton rubrum Trichophyton rubrum MIC80 0.0152 ug.mL-1 10.1016/j.ejmech.2007.01.006
Trichophyton rubrum Trichophyton rubrum MIC80 0.0156 ug.mL-1 10.1016/j.ejmech.2011.02.042
Trichophyton rubrum Trichophyton rubrum MIC80 0.0156 ug.mL-1 10.1016/j.ejmech.2011.04.022
Trichophyton rubrum Trichophyton rubrum MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2011.06.008
Trichophyton rubrum Trichophyton rubrum MIC80 0.0625 ug.mL-1 10.1016/j.bmcl.2012.02.042
Trichophyton rubrum Trichophyton rubrum MIC80 0.0625 ug.mL-1 10.1016/j.ejmech.2011.02.001
Trichophyton rubrum Trichophyton rubrum MIC80 0.0625 ug.mL-1 10.1039/C3MD20086H
Trichophyton rubrum Trichophyton rubrum MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2009.01.048
Trichophyton rubrum Trichophyton rubrum MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2009.07.144
Trichophyton rubrum Trichophyton rubrum MIC80 0.125 ug.mL-1 10.1016/j.bmcl.2012.05.070
Trichophyton rubrum Trichophyton rubrum MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2008.11.007
Trichophyton rubrum Trichophyton rubrum MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2009.05.018
Trichophyton rubrum Trichophyton rubrum MIC80 0.125 ug.mL-1 10.1016/j.ejmech.2012.04.013
Trichophyton rubrum Trichophyton rubrum MIC80 0.5 ug.mL-1 10.1016/j.bmcl.2013.11.037
Trichophyton rubrum Trichophyton rubrum MIC80 0.5 ug.mL-1 10.1016/j.ejmech.2014.05.079
Trichophyton rubrum Trichophyton rubrum MIC80 1.0 ug.mL-1 10.1021/jm051211n
Trichophyton rubrum Trichophyton rubrum MIC80 2.0 ug.mL-1 10.1021/np500024r
Trichophyton rubrum Trichophyton rubrum MIC80 4.0 ug.mL-1 10.1016/j.ejmech.2014.01.009
Trichophyton rubrum Trichophyton rubrum MIC80 4.0 ug.mL-1 10.1016/j.ejmech.2017.10.043
Trichophyton rubrum Trichophyton rubrum MIC90 0.32 ug.mL-1 10.1021/jm0494772
Trichophyton rubrum Trichophyton rubrum MIC90 4.0 ug.mL-1 10.1128/aac.01382-06
Trichophyton tonsurans Trichophyton tonsurans MIC 0.19 ug.mL-1 10.1016/j.ejmech.2020.112768
Trichophyton tonsurans Trichophyton tonsurans MIC 1.645 ug.mL-1 10.1128/aac.01382-06
Trichophyton tonsurans Trichophyton tonsurans MIC100 nan None 10.1016/j.ejmech.2009.09.024
Trichophyton tonsurans Trichophyton tonsurans MIC50 0.32 ug.mL-1 10.1021/jm0494772
Trichophyton tonsurans Trichophyton tonsurans MIC50 2.0 ug.mL-1 10.1128/aac.01382-06
Trichophyton tonsurans Trichophyton tonsurans MIC90 0.524 ug.mL-1 10.1021/jm0494772
Trichophyton tonsurans Trichophyton tonsurans MIC90 4.0 ug.mL-1 10.1128/aac.01382-06
Trichophyton violaceum Trichophyton violaceum MIC 0.19 ug.mL-1 10.1016/j.ejmech.2020.112768
Trichophyton violaceum Trichophyton violaceum MIC 3.302 ug.mL-1 10.1128/aac.01382-06
Trichosporon Trichosporon MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Trichosporon Trichosporon MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Trichosporon asahii Trichosporon asahii MFC 4.0 ug ml-1 10.1128/aac.00662-08
Trichosporon asahii Trichosporon asahii MIC 0.17 ug.mL-1 10.1128/aac.00662-08
Trichosporon asahii Trichosporon asahii MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Trichosporon asahii Trichosporon asahii MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Trichosporon inkin Trichosporon inkin MFC 0.25 ug ml-1 10.1128/aac.00662-08
Trichosporon inkin Trichosporon inkin MIC 0.21 ug.mL-1 10.1128/aac.00662-08
Trichosporon inkin Trichosporon inkin MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
Trichosporon inkin Trichosporon inkin MIC90 0.25 ug.mL-1 10.1128/aac.01543-08
Trypanosoma brucei rhodesiense Trypanosoma brucei rhodesiense IC50 8530.0 nM 10.6019/CHEMBL3392926
Trypanosoma cruzi Cruzipain IC50 3000.0 nM 10.1021/jm100254w
Trypanosoma cruzi Cruzipain IC50 200000.0 nM 10.1021/jm100254w
Trypanosoma cruzi Trypanosoma cruzi IC50 4.0 nM 10.6019/CHEMBL3392926
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 0.0 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 1.7 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 7.0 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 12.0 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 36.1 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 36.2 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 39.5 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 39.6 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 74.1 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 91.2 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 96.5 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 98.2 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus Activity 100.0 % 10.1128/aac.01038-06
Wickerhamomyces anomalus Wickerhamomyces anomalus MIC 0.25 ug.mL-1 10.1128/aac.01368-08
Wickerhamomyces anomalus Wickerhamomyces anomalus MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
Wickerhamomyces anomalus Wickerhamomyces anomalus MIC50 0.5 ug.mL-1 10.1128/aac.00459-07
Wickerhamomyces anomalus Wickerhamomyces anomalus MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
Yarrowia lipolytica Yarrowia lipolytica MIC 0.12 ug.mL-1 10.1016/j.ejmech.2015.04.047
Yarrowia lipolytica Yarrowia lipolytica MIC 0.12 ug.mL-1 10.1128/aac.01368-08
Yarrowia lipolytica Yarrowia lipolytica MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
Yarrowia lipolytica Yarrowia lipolytica MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
None ADMET Activity 13.0 % 10.1016/j.ejmech.2021.114060
None ADMET Activity nan None 10.1016/j.ejmech.2022.114137
None ADMET AUC 7400.0 ng.hr.mL-1 10.1128/aac.00663-08
None ADMET AUC 23000.0 ng.hr.mL-1 10.1021/acs.jmedchem.9b01813
None ADMET AUC 101000.0 ng.hr.mL-1 10.1128/aac.00663-08
None ADMET Biotransformation nan None 10.1038/s41586-019-1291-3
None ADMET CL 5.1 mL.min-1.kg-1 10.1124/dmd.108.020479
None ADMET CL 5.4 mL.min-1.kg-1 10.1021/acs.jmedchem.9b01813
None ADMET CL 2700.0 mL.min-1.kg-1 10.1021/acs.jmedchem.9b01813
None ADMET CLH nan None 10.1016/j.ejmech.2018.11.056
None ADMET Cmax 496.0 nM 10.1128/aac.00730-10
None ADMET Cmax 708.57 nM 10.1128/aac.00663-08
None ADMET Cmax 7794.23 nM 10.1128/aac.00663-08
None ADMET eLog D 5.79 None 10.1021/jm0200409
None ADMET F 55.0 % 10.1021/acs.jmedchem.9b01813
None ADMET fAUC 50.0 ng.hr.mL-1 10.1021/acs.jmedchem.9b01813
None ADMET Fraction ionised 0.0 None 10.1021/jm0200409
None ADMET Fu 0.002 None 10.1021/acs.jmedchem.9b01813
None ADMET Fu 0.003 None 10.1021/jm0200409
None ADMET Fu 0.028 None 10.1021/jm0200409
None ADMET Fu 0.028 None 10.1021/jm030408h
None ADMET fVdss 5000.0 L/Kg 10.1021/acs.jmedchem.9b01813
None ADMET IC50 201.63 ug.mL-1 10.1016/j.bmcl.2014.01.060
None ADMET IC50 300000.0 nM 10.1016/j.bmcl.2014.01.060
None ADMET Inhibition nan % 10.1124/dmd.110.036780
None ADMET Ki 41.0 nM 10.1124/dmd.110.036780
None ADMET Ki 45.0 nM 10.1124/dmd.110.036780
None ADMET Ki 76.0 nM 10.1124/dmd.110.036780
None ADMET Ki 82.0 nM 10.1124/dmd.110.036780
None ADMET Ki 179.0 nM 10.1124/dmd.110.036780
None ADMET MRT 24.0 hr 10.1124/dmd.108.020479
None ADMET Ratio 0.54 None 10.1124/dmd.110.036780
None ADMET Ratio 0.59 None 10.1124/dmd.110.036780
None ADMET Ratio 2.4 None 10.1124/dmd.110.036780
None ADMET Ratio 3.0 None 10.1128/aac.01407-09
None ADMET Ratio 18.0 None 10.1128/aac.01407-09
None ADMET Ratio 27.3 None 10.1128/aac.01407-09
None ADMET Ratio 44.3 None 10.1128/aac.01407-09
None ADMET Ratio 87.9 None 10.1128/aac.01407-09
None ADMET Ratio 90.4 None 10.1128/aac.01407-09
None ADMET T1/2 0.45 hr 10.1016/j.ejmech.2018.11.056
None ADMET T1/2 0.45 hr 10.1021/acs.jmedchem.8b01283
None ADMET T1/2 23.0 hr 10.1021/acs.jmedchem.9b01813
None ADMET T1/2 25.0 hr 10.1124/dmd.108.020479
None ADMET Vdss 3.9 L.kg-1 10.1021/jm0200409
None ADMET Vdss 3.9 L.kg-1 10.1021/jm030408h
None ADMET Vdss 7.4 L.kg-1 10.1124/dmd.108.020479
None ADMET Vdss 11.0 L.kg-1 10.1021/acs.jmedchem.9b01813
None B-cell Inhibition nan % None
None Erythrocyte HC10 20.0 uM 10.6019/CHEMBL4513161
None Hepatotoxicity Alkaline Phosphatase Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Index Value 12.4 None 10.2174/1570163043334794
None Hepatotoxicity Alkaline Phosphatase Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Active 5.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Marginal 0.0 None 10.2174/1570163043334794
None Hepatotoxicity Composite Activity - Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Index Value 14.1 None 10.2174/1570163043334794
None Hepatotoxicity GGT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity Hepatotoxicity nan None 10.1021/tx900326k
None Hepatotoxicity HepSE_bilirubinemia 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholecystitis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cholelithiasis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_cirrhosis 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_Combined Scores 7.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_elevated liver function tests 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic failure 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatic necrosis 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatitis 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_hepatomegaly 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_jaundice 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver disease 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver fatty 0.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity HepSE_liver function tests abnormal 1.0 None 10.1371/journal.pcbi.1002310
None Hepatotoxicity LDH Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Index Value 5.8 None 10.2174/1570163043334794
None Hepatotoxicity LDH Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Index Value 19.6 None 10.2174/1570163043334794
None Hepatotoxicity SGOT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Activity Score nan None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Index Value 19.8 None 10.2174/1570163043334794
None Hepatotoxicity SGPT Increase - Number of Reports 4.0 None 10.2174/1570163043334794
None Molecular identity unknown Activity 1.7 % 10.1021/acs.jmedchem.5b01718
None Molecular identity unknown FC 0.15 None 10.1021/jm200944b
None Molecular identity unknown IC50 63.0 nM 10.1021/acs.jmedchem.5b01718
None Molecular identity unknown IC50 140.0 nM 10.1021/acs.jmedchem.5b01718
None Molecular identity unknown IC50 390.0 nM 10.1021/acs.jmedchem.5b01718
None Molecular identity unknown IC50 690.0 nM 10.1021/acs.jmedchem.5b01718
None Molecular identity unknown MFC 0.5 ug ml-1 10.1128/aac.00662-08
None Molecular identity unknown MFC 8.0 ug ml-1 10.1128/aac.00662-08
None Molecular identity unknown MIC 0.06 ug.mL-1 10.1016/j.ejmech.2010.10.019
None Molecular identity unknown MIC 0.11 ug.mL-1 10.1128/aac.00662-08
None Molecular identity unknown MIC 0.12 ug.mL-1 10.1128/aac.00662-08
None Molecular identity unknown MIC 0.12 ug.mL-1 10.1128/aac.01368-08
None Molecular identity unknown MIC 0.125 ug.mL-1 10.1016/j.ejmech.2010.10.019
None Molecular identity unknown MIC 0.25 ug.mL-1 10.1016/j.bmcl.2013.03.098
None Molecular identity unknown MIC 0.29 ug.mL-1 10.1128/aac.01467-08
None Molecular identity unknown MIC 0.44 ug.mL-1 10.1128/aac.01467-08
None Molecular identity unknown MIC 0.5 ug.mL-1 10.1016/j.bmcl.2013.03.098
None Molecular identity unknown MIC 0.5 ug.mL-1 10.1128/aac.01270-09
None Molecular identity unknown MIC 0.92 ug.mL-1 10.1128/aac.01270-09
None Molecular identity unknown MIC 1.0 ug.mL-1 10.1016/j.ejmech.2016.02.013
None Molecular identity unknown MIC 1.0 ug.mL-1 10.1128/aac.01270-09
None Molecular identity unknown MIC 1.59 ug.mL-1 10.1128/aac.01467-08
None Molecular identity unknown MIC 2.0 ug.mL-1 10.1128/aac.00786-10
None Molecular identity unknown MIC 2.0 ug.mL-1 10.1128/aac.01177-06
None Molecular identity unknown MIC 2.38 ug.mL-1 10.1128/aac.01270-09
None Molecular identity unknown MIC 3.56 ug.mL-1 10.1128/aac.01467-08
None Molecular identity unknown MIC 8.0 ug.mL-1 10.1016/j.ejmech.2015.04.047
None Molecular identity unknown MIC 16.0 ug.mL-1 10.1128/aac.00176-08
None Molecular identity unknown MIC 16.0 ug.mL-1 10.1128/aac.00786-10
None Molecular identity unknown MIC 16.0 ug.mL-1 10.1128/aac.01177-06
None Molecular identity unknown MIC 16.0 ug.mL-1 10.1128/aac.01467-08
None Molecular identity unknown MIC 1000.0 ug.mL-1 10.1128/aac.01026-09
None Molecular identity unknown MIC 2000.0 ug.mL-1 10.1128/aac.01026-09
None Molecular identity unknown MIC 4000.0 ug.mL-1 10.1128/aac.01026-09
None Molecular identity unknown MIC nan None 10.1021/ml300429p
None Molecular identity unknown MIC nan None None
None Molecular identity unknown MIC50 0.031 ug.mL-1 10.1128/aac.01217-06
None Molecular identity unknown MIC80 0.25 ug.mL-1 10.1016/j.ejmech.2011.02.042
None Molecular identity unknown MIC80 0.25 ug.mL-1 10.1016/j.ejmech.2011.04.022
None Molecular identity unknown MIC90 0.031 ug.mL-1 10.1128/aac.01217-06
None NON-PROTEIN TARGET Activity nan None 10.1128/aac.00332-06
None NON-PROTEIN TARGET Fu 0.002 None 10.1124/dmd.108.020479
None NON-PROTEIN TARGET GI50 440.0 nM 10.1021/acs.jmedchem.5b01718
None NON-PROTEIN TARGET Hepatotoxicity (acute) 30.0 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (animal toxicity known) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (benign tumour) 1.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (granulomatous hepatitis) 0.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (mechanism) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 55.0 None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (moderate) 91.7 % 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET Hepatotoxicity (time to onset) nan None 10.1016/s0399-8320(04)95062-2
None NON-PROTEIN TARGET IC50 55.0 nM 10.1039/C3MD00334E
None NON-PROTEIN TARGET IC50 1110.0 nM 10.6019/CHEMBL3392926
None NON-PROTEIN TARGET IC50 4250.0 nM 10.6019/CHEMBL3392926
None NON-PROTEIN TARGET MFC50 1.56 ug ml-1 10.1128/aac.00332-06
None NON-PROTEIN TARGET MFC90 6.25 ug ml-1 10.1128/aac.00332-06
None NON-PROTEIN TARGET MIC 0.016 ug.mL-1 10.1128/aac.01384-07
None NON-PROTEIN TARGET MIC 0.031 ug.mL-1 10.1128/aac.01655-09
None NON-PROTEIN TARGET MIC 0.12 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 0.16 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 0.185 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1016/j.bmc.2016.11.051
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1016/j.ejmech.2010.10.019
None NON-PROTEIN TARGET MIC 0.25 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 0.33 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 0.43 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1016/j.bmc.2016.11.051
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00692-10
None NON-PROTEIN TARGET MIC 0.5 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 0.62 ug.mL-1 10.1128/aac.00184-09
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1016/j.bmc.2016.11.051
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 10.1128/aac.00585-09
None NON-PROTEIN TARGET MIC 1.0 ug.mL-1 None
None NON-PROTEIN TARGET MIC 2.0 ug.mL-1 10.1128/aac.01467-08
None NON-PROTEIN TARGET MIC 3.42 ug.mL-1 10.1128/aac.01382-06
None NON-PROTEIN TARGET MIC 5.2 ug.mL-1 10.1021/jm970726e
None NON-PROTEIN TARGET MIC 5.2 ug.mL-1 10.1021/jm9707277
None NON-PROTEIN TARGET MIC 6.0 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 6.66 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 7.0 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 8.0 ug.mL-1 10.1128/aac.01177-06
None NON-PROTEIN TARGET MIC 8.25 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 9.25 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 10.25 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 11.0 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 13.4 ug.mL-1 10.1128/aac.00538-08
None NON-PROTEIN TARGET MIC 14.4 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.00585-09
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.00942-07
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.01177-06
None NON-PROTEIN TARGET MIC 16.0 ug.mL-1 10.1128/aac.01467-08
None NON-PROTEIN TARGET MIC 63.0 ug.mL-1 10.1021/jm970726e
None NON-PROTEIN TARGET MIC 63.0 ug.mL-1 10.1021/jm9707277
None NON-PROTEIN TARGET MIC 35400.0 nM 10.1021/jm031089x
None NON-PROTEIN TARGET MIC nan None None
None NON-PROTEIN TARGET MIC50 0.031 ug.mL-1 10.1128/aac.01384-07
None NON-PROTEIN TARGET MIC50 0.032 ug.mL-1 10.1021/jm0494772
None NON-PROTEIN TARGET MIC50 0.063 ug.mL-1 10.1128/aac.01384-07
None NON-PROTEIN TARGET MIC50 0.063 ug.mL-1 10.1128/aac.01655-09
None NON-PROTEIN TARGET MIC50 0.1 ug.mL-1 10.1021/jm0494772
None NON-PROTEIN TARGET MIC50 0.12 ug.mL-1 10.1128/aac.01543-08
None NON-PROTEIN TARGET MIC50 0.125 ug.mL-1 10.1128/aac.01655-09
None NON-PROTEIN TARGET MIC50 0.5 ug.mL-1 10.1128/aac.01543-08
None NON-PROTEIN TARGET MIC50 0.78 ug.mL-1 10.1128/aac.00332-06
None NON-PROTEIN TARGET MIC50 2.0 ug.mL-1 10.1128/aac.01543-08
None NON-PROTEIN TARGET MIC50 8.0 ug.mL-1 10.1128/aac.01543-08
None NON-PROTEIN TARGET MIC90 0.063 ug.mL-1 10.1128/aac.01384-07
None NON-PROTEIN TARGET MIC90 0.125 ug.mL-1 10.1128/aac.01384-07
None NON-PROTEIN TARGET MIC90 0.125 ug.mL-1 10.1128/aac.01655-09
None NON-PROTEIN TARGET MIC90 0.25 ug.mL-1 10.1128/aac.01384-07
None NON-PROTEIN TARGET MIC90 0.25 ug.mL-1 10.1128/aac.01655-09
None NON-PROTEIN TARGET MIC90 0.524 ug.mL-1 10.1021/jm0494772
None NON-PROTEIN TARGET MIC90 1.0 ug.mL-1 10.1021/jm0494772
None NON-PROTEIN TARGET MIC90 1.56 ug.mL-1 10.1128/aac.00332-06
None NON-PROTEIN TARGET MIC90 8.0 ug.mL-1 10.1128/aac.01543-08
None NON-PROTEIN TARGET Potency 1332.4 nM None
None No relevant target Activity 2.5 uM 10.1021/jm100254w
None No relevant target Activity 6.9 % 10.1021/jm100254w
None No relevant target Activity 64.5 nm 10.1021/jm100254w
None No relevant target Activity 138.1 nm 10.1021/jm100254w
None No relevant target Activity nan None 10.1021/jm100254w
None No relevant target LogP 6.5 None 10.1021/jm021012t
None No relevant target log Pe -8.8 None 10.1021/acs.jmedchem.8b01283
None No relevant target pKa 3.7 None 10.1021/acs.jmedchem.1c00790
None No relevant target pKa 14.98 None 10.1124/dmd.112.050278
None No relevant target pKa nan None 10.1021/jm0200409
None No relevant target pKa nan None 10.1021/jm030408h
None No relevant target solubility nan None 10.1016/j.bmcl.2011.06.062
None No relevant target Solubility 0.0101 ug.mL-1 10.1021/acsmedchemlett.9b00438
None No relevant target Solubility 1.8 ug.mL-1 10.1016/j.bmcl.2011.06.062
None No relevant target Solubility 3.3 nM 10.1021/jm0706416
None No relevant target Solubility 800.0 nM 10.1016/j.ejmech.2018.11.056
None No relevant target Solubility 800.0 nM 10.1021/acs.jmedchem.8b01283
None Unchecked AbsAC35_uM 105.6 uM None
None Unchecked Ac50 0.631 uM None
None Unchecked Ac50 1.995 uM None
None Unchecked Ac50 2.512 uM None
None Unchecked Ac50 5.012 uM None
None Unchecked Ac50 39.81 uM None
None Unchecked AC50 631.0 nM None
None Unchecked AC50 2000.0 nM None
None Unchecked AC50 2511.9 nM None
None Unchecked AC50 5011.9 nM None
None Unchecked AC50 39810.7 nM None
None Unchecked Activity nan None 10.1016/j.ejmech.2010.07.050
None Unchecked Activity nan None 10.1021/jm100254w
None Unchecked EC50 100.0 nM None
None Unchecked EC50 49951.0 nM None
None Unchecked EC50 60000.0 nM None
None Unchecked EC50 120000.0 nM None
None Unchecked Hepatotoxicity (acute) 18.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (association with vascular disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (choleostasis) 10.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (chronic liver disease) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cirrhosis) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (comment) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (cytolytic) 10.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (malignant tumour) 0.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (severe hepatitis) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (steatosis) 1.0 None 10.1016/s0399-8320(04)95062-2
None Unchecked Hepatotoxicity (successful reintroduction) nan None 10.1016/s0399-8320(04)95062-2
None Unchecked IC50 125.0 nM 10.1016/j.bmcl.2022.129011
None Unchecked IC50 140.0 nM 10.1016/j.bmcl.2019.126794
None Unchecked IC50 140.0 nM 10.1021/acsmedchemlett.9b00188
None Unchecked IC50 170.0 nM 10.1021/acsmedchemlett.9b00438
None Unchecked IC50 500.0 nM 10.1016/j.ejmech.2022.114867
None Unchecked IC50 690.0 nM 10.1016/j.bmcl.2018.08.033
None Unchecked IC50 800.0 nM 10.1016/j.bmc.2010.07.038
None Unchecked IC50 800.0 nM 10.1021/acs.jmedchem.9b00188
None Unchecked IC50 1548.8 nM None
None Unchecked IC50 2050.0 nM 10.1021/acs.jmedchem.1c01710
None Unchecked IC50 2577.0 nM None
None Unchecked IC50 9300.0 nM 10.1016/j.bmc.2021.116458
None Unchecked IC50 10000.0 nM None
None Unchecked IC50 nan None None
None Unchecked Inhibition nan % 10.1021/acsmedchemlett.9b00188
None Unchecked Kd 100.0 nM 10.1128/aac.00446-08
None Unchecked Kd 780.0 nM 10.1128/aac.01237-08
None Unchecked Kd 1110.0 nM 10.1128/aac.01237-08
None Unchecked Kd 1260.0 nM 10.1128/aac.01237-08
None Unchecked Kd 3000.0 nM 10.1128/aac.01237-08
None Unchecked Ki 2351.0 nM None
None Unchecked Ki nan None None
None Unchecked MIC 100.0 ug.mL-1 10.1016/j.ejmech.2020.112768
None Unchecked Potency 0.9 nM None
None Unchecked Potency 525.8 nM None
None Unchecked Potency 742.7 nM None
None Unchecked Potency 1320.7 nM None
None Unchecked Potency 1778.3 nM None
None Unchecked Potency 5011.9 nM None
None Unchecked Potency 8332.8 nM None
None Unchecked Potency 10490.4 nM None
None Unchecked Potency 11220.2 nM None
None Unchecked Potency 14125.4 nM None
None Unchecked Potency 16626.1 nM None
None Unchecked Ratio 3.0 None 10.1128/aac.01237-08
None Unchecked Ratio 128.0 None 10.1016/j.ejmech.2021.113740
None Unchecked Ratio IC50 1.0 None 10.1021/jm200944b
None Unchecked Ratio IC50 100.0 None 10.1016/j.ejmech.2013.06.018
None Unchecked Selectivity Index 1.1 None 10.1016/j.bmcl.2014.05.068

Metabolism Information