None
AlkaPlorer ID: AK323006
Synonym: None
IUPAC Name: N-[1-[(5R,6S)-5,6-dihydroxy-1,3,3,4a-tetramethyl-4,7-dioxo-2,5-dihydrocyclopenta[c]pyridin-6-yl]-2-methylpropan-2-yl]acetamide
Structure
SMILES: CC(O)=NC(C)(C)C[C@@]1(O)C(=O)C2=C(C)NC(C)(C)C(=O)C2(C)[C@H]1O
InChI: InChI=1S/C18H28N2O5/c1-9-11-12(22)18(25,8-15(3,4)20-10(2)21)14(24)17(11,7)13(23)16(5,6)19-9/h14,19,24-25H,8H2,1-7H3,(H,20,21)/t14-,17?,18-/m1/s1
InChIKey: DJHKGUNMLJKYQF-FHKHCFAMSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Anacyclus pyrethrum | Anacyclus | Asteraceae | Asterales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 352.4310000000001
TPSA？: 119.22
MolLogP？: 1.0374
Number of H-Donors: 4
Number of H-Acceptors: 6
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Menin | Inhibition | 50.0 | % | 10.1021/acs.jnatprod.8b00239 |