None
AlkaPlorer ID: AK323180
Synonym: None
IUPAC Name: 9-(3-hydroxy-4-methoxyphenyl)-6,7,8-trimethoxy-4,9-dihydro-3H-furo[3,4-b]quinolin-1-one
Structure
SMILES: COC1=CC=C(C2C3=C(COC3=O)NC3=CC(OC)=C(OC)C(OC)=C32)C=C1O
InChI: InChI=1S/C21H21NO7/c1-25-14-6-5-10(7-13(14)23)16-17-11(22-12-9-29-21(24)18(12)16)8-15(26-2)19(27-3)20(17)28-4/h5-8,16,22-23H,9H2,1-4H3
InChIKey: IBGDVWJNEJOUPY-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Bridelia ferruginea | Bridelia | Phyllanthaceae | Malpighiales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 399.39900000000017
TPSA？: 95.48000000000002
MolLogP？: 2.794900000000001
Number of H-Donors: 2
Number of H-Acceptors: 8
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | MCF7 | GI50 | 7.0 | ug.mL-1 | 10.1021/acs.jnatprod.5b00873 |
| Homo sapiens | NCI-H460 | GI50 | 10.1 | ug.mL-1 | 10.1021/acs.jnatprod.5b00873 |
| Mus musculus | P388 | ED50 | 0.78 | ug ml-1 | 10.1021/acs.jnatprod.5b00873 |
| None | NON-PROTEIN TARGET | GI50 | 6.5 | ug.mL-1 | 10.1021/acs.jnatprod.5b00873 |
| None | NON-PROTEIN TARGET | GI50 | 7.3 | ug.mL-1 | 10.1021/acs.jnatprod.5b00873 |
| None | NON-PROTEIN TARGET | GI50 | 10.0 | ug.mL-1 | 10.1021/acs.jnatprod.5b00873 |
| None | NON-PROTEIN TARGET | GI50 | nan | None | 10.1021/acs.jnatprod.5b00873 |