(1S,6S,8S,8Ar)-1,6,8-Trihydroxyindolizidine
AlkaPlorer ID: AK323209
Synonym: None
IUPAC Name: (1S,6S,8S,8aR)-1,2,3,5,6,7,8,8a-octahydroindolizine-1,6,8-triol
Structure
SMILES: O[C@H]1C[C@H](O)[C@H]2[C@@H](O)CCN2C1
InChI: InChI=1S/C8H15NO3/c10-5-3-7(12)8-6(11)1-2-9(8)4-5/h5-8,10-12H,1-4H2/t5-,6-,7-,8+/m0/s1
InChIKey: CTNHKDHQKRJTIU-DKXJUACHSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Castanospermum australe | Castanospermum | Fabaceae | Fabales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 173.21199999999993
TPSA？: 63.93
MolLogP？: -1.4529
Number of H-Donors: 3
Number of H-Acceptors: 4
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bos taurus | Beta-glucuronidase | Activity | nan | None | 10.1021/np50069a011 |
| Rattus norvegicus | Sucrase-isomaltase | Activity | nan | None | 10.1021/np50069a011 |
| Rattus norvegicus | Sucrase-isomaltase | Inhibition | 30.0 | % | 10.1021/np50069a011 |
| None | Unchecked | Activity | nan | None | 10.1021/np50069a011 |
| None | Unchecked | Inhibition | 20.0 | % | 10.1021/np50069a011 |
| None | Unchecked | Inhibition | 35.0 | % | 10.1021/np50069a011 |
| None | Unchecked | Inhibition | 50.0 | % | 10.1021/np50069a011 |