None
AlkaPlorer ID: AK323331
Synonym: None
IUPAC Name: (4S)-2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane
Structure
SMILES: ClC1=NC=C(C2C[C@@H]3CCC2N3)C=C1
InChI: InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9?,10?/m0/s1
InChIKey: NLPRAJRHRHZCQQ-IDKOKCKLSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Drimys winteri | Drimys | Winteraceae | Canellales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 208.692
TPSA？: 24.92
MolLogP？: 2.3429
Number of H-Donors: 1
Number of H-Acceptors: 2
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Neuronal acetylcholine receptor; alpha3/beta4 | Activity | nan | None | 10.1021/acs.jnatprod.7b00893 |
| Homo sapiens | Neuronal acetylcholine receptor; alpha4/beta2 | Activity | nan | None | 10.1021/acs.jnatprod.7b00893 |
| Homo sapiens | Neuronal acetylcholine receptor; alpha4/beta2 | Inhibition | nan | % | 10.1021/acs.jnatprod.7b00893 |
| Homo sapiens | Neuronal acetylcholine receptor; alpha4/beta2 | Ki | 0.05 | nM | 10.1016/j.bmcl.2003.07.035 |
| Homo sapiens | Neuronal acetylcholine receptor protein alpha-7 subunit | Activity | nan | None | 10.1021/acs.jnatprod.7b00893 |