None
AlkaPlorer ID: AK323626
Synonym: None
IUPAC Name: (13aS)-3,9,10-trihydroxy-2,4-dimethoxy-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
Structure
SMILES: COC1=CC2=C(CCN3C(=O)C4=C(O)C(O)=CC=C4C[C@@H]23)C(OC)=C1O
InChI: InChI=1S/C19H19NO6/c1-25-14-8-11-10(18(26-2)17(14)23)5-6-20-12(11)7-9-3-4-13(21)16(22)15(9)19(20)24/h3-4,8,12,21-23H,5-7H2,1-2H3/t12-/m0/s1
InChIKey: GRFDYPYGHWGVQE-LBPRGKRZSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Miliusa cuneata | Miliusa | Annonaceae | Magnoliales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 357.3620000000002
TPSA？: 99.46
MolLogP？: 2.1163000000000003
Number of H-Donors: 3
Number of H-Acceptors: 6
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Chlorocebus sabaeus | Vero | IC50 | 47800.0 | nM | 10.1021/acs.jnatprod.5b01054 |
| Homo sapiens | KB | IC50 | 47800.0 | nM | 10.1021/acs.jnatprod.5b01054 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 26100.0 | nM | 10.1021/acs.jnatprod.5b01054 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 38100.0 | nM | 10.1021/acs.jnatprod.5b01054 |