None
AlkaPlorer ID: AK323689
Synonym: None
IUPAC Name: N-(2-azidoethyl)-2-[(2R)-2-methyl-2-[(1E)-2-methylbuta-1,3-dienyl]-5-oxothiophen-3-yl]oxyacetamide
Structure
SMILES: C=C/C(C)=C/[C@@]1(C)SC(=O)C=C1OCC(O)=NCCN=[N+]=[N-]
InChI: InChI=1S/C14H18N4O3S/c1-4-10(2)8-14(3)11(7-13(20)22-14)21-9-12(19)16-5-6-17-18-15/h4,7-8H,1,5-6,9H2,2-3H3,(H,16,19)/b10-8+/t14-/m1/s1
InChIKey: GUFIEOGGCSKHND-QSYFUGGGSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 322.39000000000004
TPSA？: 107.65
MolLogP？: 3.318100000000001
Number of H-Donors: 1
Number of H-Acceptors: 5
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Francisella tularensis | Francisella tularensis | MIC90 | 39.0 | ug.mL-1 | 10.1021/acs.jmedchem.6b00236 |
| Mycobacterium tuberculosis | Mycobacterium tuberculosis | MIC90 | 100.0 | ug.mL-1 | 10.1021/acs.jmedchem.6b00236 |
| Staphylococcus aureus | Staphylococcus aureus | MIC90 | 64.0 | ug.mL-1 | 10.1021/acs.jmedchem.6b00236 |
| None | Unchecked | Activity | nan | None | 10.1021/acs.jmedchem.6b00236 |
| None | Unchecked | Ki | 200000.0 | nM | 10.1021/acs.jmedchem.6b00236 |