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name Structure Reference Source Properties Activities Metabolism

None

AlkaPlorer ID: AK323800

Synonym: None

IUPAC Name: N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-N-methylbenzamide

Structure

SMILES: CO[C@@H]1[C@H](N(C)C(=O)C2=CC=CC=C2)C[C@H]2O[C@]1(C)N1C3=CC=CC=C3C3=C4CN=C(O)C4=C4C5=CC=CC=C5N2C4=C31

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InChI: InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1

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InChIKey: BMGQWWVMWDBQGC-IIFHNQTCSA-N

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Reference

PubChem CID: 9829523

CAS: 120685-11-2

NPASS: NPC484828

Source

Species Genus Family Order Class Phylum Kingdom Domain

Properties Information

Molecule Weight: 570.6490000000002

TPSA？: 81.22

MolLogP？: 6.481600000000007

Number of H-Donors: 1

Number of H-Acceptors: 6

RingCount: 9

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Chlorocebus sabaeus Vero C1008 AUC cytotoxicity 144.2 None 10.1038/s41586-020-2286-9
Chlorocebus sabaeus Vero C1008 pCC50 7.924 None 10.1038/s41586-020-2286-9
Gallus gallus Myosin light chain kinase, smooth muscle Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens 23132-87 IC50 4638.37 nM 10.6019/CHEMBL1201861
Homo sapiens 26S protease regulatory subunit 6B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Kd 110.0 nM 10.1182/blood-2009-05-222034
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Kd 190.0 nM 10.1038/nbt1358
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Kd 190.0 nM 10.1038/nbt.1990
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Residual Activity 2.0 % 10.1042/bj20121418
Homo sapiens 5637 IC50 1774.22 nM 10.6019/CHEMBL1201861
Homo sapiens 639-V IC50 920.63 nM 10.6019/CHEMBL1201861
Homo sapiens 647-V IC50 12097.24 nM 10.6019/CHEMBL1201861
Homo sapiens 697 IC50 671.32 nM 10.6019/CHEMBL1201861
Homo sapiens 769-P IC50 120.82 nM 10.6019/CHEMBL1201861
Homo sapiens 786-0 IC50 473.44 nM 10.6019/CHEMBL1201861
Homo sapiens 8305C IC50 1680.34 nM 10.6019/CHEMBL1201861
Homo sapiens 8505C IC50 276.04 nM 10.6019/CHEMBL1201861
Homo sapiens 8-MG-BA IC50 198.1 nM 10.6019/CHEMBL1201861
Homo sapiens A101D IC50 587.89 nM 10.6019/CHEMBL1201861
Homo sapiens A 172 IC50 291.5 nM 10.6019/CHEMBL1201861
Homo sapiens A204 IC50 100.52 nM 10.6019/CHEMBL1201861
Homo sapiens A2058 IC50 528.44 nM 10.6019/CHEMBL1201861
Homo sapiens A253 cell line IC50 4903.07 nM 10.6019/CHEMBL1201861
Homo sapiens A2780 IC50 475.03 nM 10.6019/CHEMBL1201861
Homo sapiens A-375 IC50 180.0 nM 10.1182/blood-2009-05-222034
Homo sapiens A-375 IC50 561.03 nM 10.6019/CHEMBL1201861
Homo sapiens A388 IC50 12699.66 nM 10.6019/CHEMBL1201861
Homo sapiens A3-KAW IC50 839.93 nM 10.6019/CHEMBL1201861
Homo sapiens A-427 IC50 119.18 nM 10.6019/CHEMBL1201861
Homo sapiens A-431 IC50 112.16 nM 10.6019/CHEMBL1201861
Homo sapiens A498 IC50 476.93 nM 10.6019/CHEMBL1201861
Homo sapiens A4-Fuk IC50 560.48 nM 10.6019/CHEMBL1201861
Homo sapiens A673 IC50 1170.69 nM 10.6019/CHEMBL1201861
Homo sapiens A704 IC50 409.17 nM 10.6019/CHEMBL1201861
Homo sapiens ABC-1 IC50 134.15 nM 10.6019/CHEMBL1201861
Homo sapiens ACHN IC50 331.17 nM 10.6019/CHEMBL1201861
Homo sapiens ACN IC50 648.32 nM 10.6019/CHEMBL1201861
Homo sapiens Actin-related protein 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Actin-related protein 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Activin receptor type-1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Activin receptor type-1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Activin receptor type-1B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-1B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-1B Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Activin receptor type-1B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Activin receptor type-1B Residual Activity 102.0 % 10.1042/bj20121418
Homo sapiens Activin receptor type-1B Residual Activity 128.0 % 10.1042/bj20121418
Homo sapiens Activin receptor type-2A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-2A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-2A Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Activin receptor type-2B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-2B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-2B Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Activin receptor type-2B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Adaptor-associated kinase IC50 200.0 nM 10.1021/acs.jmedchem.0c01467
Homo sapiens Adaptor-associated kinase Kd 48.0 nM 10.1038/nbt1358
Homo sapiens Adaptor-associated kinase Kd 48.0 nM 10.1038/nbt.1990
Homo sapiens Adaptor-associated kinase Kd 48.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Adaptor-associated kinase Kd 413.0 nM 10.1126/science.aan4368
Homo sapiens Adenosine kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Adenylate kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ADP/ATP translocase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ADP/ATP translocase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens AGS IC50 173.52 nM 10.6019/CHEMBL1201861
Homo sapiens ALK tyrosine kinase receptor Kd 270.0 nM 10.1038/nbt1358
Homo sapiens ALK tyrosine kinase receptor Kd 270.0 nM 10.1038/nbt.1990
Homo sapiens ALK tyrosine kinase receptor Kd 270.0 nM 10.1182/blood-2009-05-222034
Homo sapiens ALK tyrosine kinase receptor Residual Activity 32.0 % 10.1042/bj20121418
Homo sapiens ALK tyrosine kinase receptor Residual Activity 33.0 % 10.1042/bj20121418
Homo sapiens ALL-PO IC50 145.46 nM 10.6019/CHEMBL1201861
Homo sapiens AM-38 IC50 728.71 nM 10.6019/CHEMBL1201861
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd 180.0 nM 10.1038/nbt1358
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd 180.0 nM 10.1038/nbt.1990
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd 180.0 nM 10.1182/blood-2009-05-222034
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd 12843.0 nM 10.1126/science.aan4368
Homo sapiens AMP-activated protein kinase, alpha-2 subunit Kd 460.0 nM 10.1038/nbt1358
Homo sapiens AMP-activated protein kinase, alpha-2 subunit Kd 460.0 nM 10.1038/nbt.1990
Homo sapiens AMP-activated protein kinase, alpha-2 subunit Kd 460.0 nM 10.1182/blood-2009-05-222034
Homo sapiens AMP-activated protein kinase, AMPK Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens AMP-activated protein kinase, AMPK Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1 Residual Activity 6.0 % 10.1042/bj20121418
Homo sapiens AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1 Residual Activity 10.0 % 10.1042/bj20121418
Homo sapiens AMP-activated protein kinase, gamma-1 subunit Kd 1168.0 nM 10.1126/science.aan4368
Homo sapiens AMP-activated protein kinase, gamma-2 subunit Kd 9128.0 nM 10.1126/science.aan4368
Homo sapiens AN3-CA IC50 321.98 nM 10.6019/CHEMBL1201861
Homo sapiens Ankyrin repeat and protein kinase domain-containing protein 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ankyrin repeat and protein kinase domain-containing protein 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ankyrin repeat and protein kinase domain-containing protein 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens ARH-77 IC50 3146.05 nM 10.6019/CHEMBL1201861
Homo sapiens Aspartyl/asparaginyl beta-hydroxylase IC50 6020.0 nM 10.1016/j.bmc.2020.115675
Homo sapiens Aspartyl/asparaginyl beta-hydroxylase IC50 7280.0 nM 10.1016/j.bmc.2020.115675
Homo sapiens Aspartyl/asparaginyl beta-hydroxylase IC50 9430.0 nM 10.1016/j.bmc.2020.115675
Homo sapiens Aspartyl/asparaginyl beta-hydroxylase IC50 12400.0 nM 10.1016/j.bmc.2020.115675
Homo sapiens Aspartyl/asparaginyl beta-hydroxylase Inhibition 91.7 % 10.1016/j.bmc.2020.115675
Homo sapiens ASPC1 IC50 9859.35 nM 10.6019/CHEMBL1201861
Homo sapiens ATN-1 IC50 8652.95 nM 10.6019/CHEMBL1201861
Homo sapiens ATP-dependent RNA helicase DDX1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ATP-dependent RNA helicase DDX3X Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens AU565 IC50 5548.49 nM 10.6019/CHEMBL1201861
Homo sapiens BB30-HNC IC50 323.67 nM 10.6019/CHEMBL1201861
Homo sapiens BB49-HNC IC50 5779.4 nM 10.6019/CHEMBL1201861
Homo sapiens BB65-RCC IC50 1474.36 nM 10.6019/CHEMBL1201861
Homo sapiens BC-3 IC50 487.41 nM 10.6019/CHEMBL1201861
Homo sapiens BCPAP IC50 298.79 nM 10.6019/CHEMBL1201861
Homo sapiens Bcr/Abl fusion protein GI50 20000.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens BE-13 IC50 4360.27 nM 10.6019/CHEMBL1201861
Homo sapiens Becker IC50 2694.75 nM 10.6019/CHEMBL1201861
Homo sapiens BEN IC50 3214.81 nM 10.6019/CHEMBL1201861
Homo sapiens BFTC-905 IC50 254.58 nM 10.6019/CHEMBL1201861
Homo sapiens BFTC-909 IC50 310.7 nM 10.6019/CHEMBL1201861
Homo sapiens BHT-101 IC50 2196.54 nM 10.6019/CHEMBL1201861
Homo sapiens BHY IC50 2349.12 nM 10.6019/CHEMBL1201861
Homo sapiens BL-41 IC50 925.39 nM 10.6019/CHEMBL1201861
Homo sapiens BL-70 IC50 7586.85 nM 10.6019/CHEMBL1201861
Homo sapiens BMP-2-inducible protein kinase Kd 220.0 nM 10.1038/nbt1358
Homo sapiens BMP-2-inducible protein kinase Kd 220.0 nM 10.1038/nbt.1990
Homo sapiens BMP-2-inducible protein kinase Kd 220.0 nM 10.1182/blood-2009-05-222034
Homo sapiens BMP-2-inducible protein kinase Kd 528.0 nM 10.1126/science.aan4368
Homo sapiens BOKU IC50 1569.7 nM 10.6019/CHEMBL1201861
Homo sapiens Bone morphogenetic protein receptor type-1A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Bone morphogenetic protein receptor type-1A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Bone morphogenetic protein receptor type-1A Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Bone morphogenetic protein receptor type-1A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Bone morphogenetic protein receptor type-1B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Bone morphogenetic protein receptor type-1B Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Bone morphogenetic protein receptor type-1B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Bone morphogenetic protein receptor type-2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Bone morphogenetic protein receptor type-2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Bone morphogenetic protein receptor type-2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Bone morphogenetic protein receptor type-2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens BPH-1 IC50 10377.71 nM 10.6019/CHEMBL1201861
Homo sapiens Brain glycogen phosphorylase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Breakpoint cluster region protein Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens BR serine/threonine-protein kinase 1 Kd 1200.0 nM 10.1038/nbt1358
Homo sapiens BR serine/threonine-protein kinase 1 Kd 1200.0 nM 10.1038/nbt.1990
Homo sapiens BR serine/threonine-protein kinase 1 Kd 1200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens BR serine/threonine-protein kinase 1 Residual Activity 3.0 % 10.1042/bj20121418
Homo sapiens BR serine/threonine-protein kinase 2 Kd 650.0 nM 10.1038/nbt1358
Homo sapiens BR serine/threonine-protein kinase 2 Kd 650.0 nM 10.1038/nbt.1990
Homo sapiens BR serine/threonine-protein kinase 2 Kd 650.0 nM 10.1182/blood-2009-05-222034
Homo sapiens BR serine/threonine-protein kinase 2 Residual Activity 3.0 % 10.1042/bj20121418
Homo sapiens BR serine/threonine-protein kinase 2 Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens BT-20 IC50 3665.3 nM 10.6019/CHEMBL1201861
Homo sapiens BT-474 IC50 86167.92 nM 10.6019/CHEMBL1201861
Homo sapiens BV-173 IC50 5448.99 nM 10.6019/CHEMBL1201861
Homo sapiens BXPC-3 IC50 493.66 nM 10.6019/CHEMBL1201861
Homo sapiens C2BBe1 IC50 13714.96 nM 10.6019/CHEMBL1201861
Homo sapiens C32 IC50 21863.51 nM 10.6019/CHEMBL1201861
Homo sapiens C-33-A IC50 2260.63 nM 10.6019/CHEMBL1201861
Homo sapiens C3A IC50 1445.39 nM 10.6019/CHEMBL1201861
Homo sapiens C-4-II IC50 348.89 nM 10.6019/CHEMBL1201861
Homo sapiens C8166 IC50 4487.93 nM 10.6019/CHEMBL1201861
Homo sapiens CA46 IC50 628.85 nM 10.6019/CHEMBL1201861
Homo sapiens Ca9-22 IC50 15300.61 nM 10.6019/CHEMBL1201861
Homo sapiens CAKI-1 IC50 215.05 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-120 IC50 210.61 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-12T IC50 280.01 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-148 IC50 18543.01 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-27 IC50 73258.85 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-33 IC50 11994.59 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-39 IC50 437.19 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-51 IC50 107.09 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-54 IC50 208.59 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-62 IC50 932.35 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-72 IC50 20177.52 nM 10.6019/CHEMBL1201861
Homo sapiens CAL-85-1 IC50 565.18 nM 10.6019/CHEMBL1201861
Homo sapiens Calu-1 IC50 2124.05 nM 10.6019/CHEMBL1201861
Homo sapiens Calu-3 IC50 368.25 nM 10.6019/CHEMBL1201861
Homo sapiens Calu-6 IC50 15958.24 nM 10.6019/CHEMBL1201861
Homo sapiens CAMA-1 IC50 21295.8 nM 10.6019/CHEMBL1201861
Homo sapiens CaM kinase I alpha Kd 2000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase I alpha Kd 2000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase I alpha Kd 2000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase I alpha Residual Activity 29.0 % 10.1042/bj20121418
Homo sapiens CaM kinase I alpha Residual Activity 84.0 % 10.1042/bj20121418
Homo sapiens CaM kinase I delta Kd 670.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase I delta Kd 670.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase I delta Kd 670.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase I delta Residual Activity 23.0 % 10.1042/bj20121418
Homo sapiens CaM kinase I delta Residual Activity 42.0 % 10.1042/bj20121418
Homo sapiens CaM kinase I gamma Kd 1800.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase I gamma Kd 1800.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II alpha Kd 20.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II alpha Kd 20.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II alpha Kd 20.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase II beta Kd 210.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II beta Kd 210.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II beta Kd 210.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase II beta Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens CaM kinase II beta Residual Activity 18.0 % 10.1042/bj20121418
Homo sapiens CaM kinase II delta Kd 36.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II delta Kd 36.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II delta Kd 36.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase II delta Kd 588.0 nM 10.1126/science.aan4368
Homo sapiens CaM kinase II delta Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens CaM kinase II delta Residual Activity 5.0 % 10.1042/bj20121418
Homo sapiens CaM kinase II gamma Kd 140.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II gamma Kd 140.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II gamma Kd 140.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase II gamma Kd 380.0 nM 10.1126/science.aan4368
Homo sapiens CaM kinase II gamma Kd 1800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase II gamma Residual Activity -1.0 % 10.1042/bj20121418
Homo sapiens CaM kinase II gamma Residual Activity 10.0 % 10.1042/bj20121418
Homo sapiens CaM kinase IV Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase IV Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase IV Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM kinase IV Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens CaM kinase IV Residual Activity 50.0 % 10.1042/bj20121418
Homo sapiens CaM kinase IV Residual Activity 98.0 % 10.1042/bj20121418
Homo sapiens CaM-kinase kinase alpha Kd 130.0 nM 10.1038/nbt1358
Homo sapiens CaM-kinase kinase alpha Kd 130.0 nM 10.1038/nbt.1990
Homo sapiens CaM-kinase kinase alpha Kd 130.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM-kinase kinase beta Kd 73.0 nM 10.1038/nbt1358
Homo sapiens CaM-kinase kinase beta Kd 73.0 nM 10.1038/nbt.1990
Homo sapiens CaM-kinase kinase beta Kd 73.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CaM-kinase kinase beta Kd 3616.0 nM 10.1126/science.aan4368
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Kd 720.0 nM 10.1038/nbt1358
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Kd 720.0 nM 10.1038/nbt.1990
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Residual Activity 10.0 % 10.1042/bj20121418
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Residual Activity 13.0 % 10.1042/bj20121418
Homo sapiens cAMP-dependent protein kinase beta-1 catalytic subunit Kd 240.0 nM 10.1038/nbt1358
Homo sapiens cAMP-dependent protein kinase beta-1 catalytic subunit Kd 240.0 nM 10.1038/nbt.1990
Homo sapiens cAMP-dependent protein kinase beta-1 catalytic subunit Kd 240.0 nM 10.1182/blood-2009-05-222034
Homo sapiens cAMP-dependent protein kinase beta-1 catalytic subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cAMP-dependent protein kinase, gamma catalytic subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cAMP-dependent protein kinase type II-alpha regulatory subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Caov-3 cell line IC50 41531.7 nM 10.6019/CHEMBL1201861
Homo sapiens Caov-4 IC50 1916.96 nM 10.6019/CHEMBL1201861
Homo sapiens CAPAN-1 IC50 2247.87 nM 10.6019/CHEMBL1201861
Homo sapiens Capan-2 IC50 2766.4 nM 10.6019/CHEMBL1201861
Homo sapiens CaR-1 IC50 644.76 nM 10.6019/CHEMBL1201861
Homo sapiens CAS-1 IC50 181.65 nM 10.6019/CHEMBL1201861
Homo sapiens Casein kinase I alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I alpha Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I delta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I delta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I delta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I delta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I delta Residual Activity 69.0 % 10.1042/bj20121418
Homo sapiens Casein kinase I delta Residual Activity 80.0 % 10.1042/bj20121418
Homo sapiens Casein kinase I epsilon IC50 10000.0 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Casein kinase I epsilon Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I epsilon Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I epsilon Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I epsilon Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I gamma 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I gamma 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I gamma 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I gamma 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I gamma 1 Residual Activity 49.0 % 10.1042/bj20121418
Homo sapiens Casein kinase I gamma 1 Residual Activity 66.0 % 10.1042/bj20121418
Homo sapiens Casein kinase I gamma 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I gamma 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I gamma 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I gamma 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I gamma 2 Residual Activity 68.0 % 10.1042/bj20121418
Homo sapiens Casein kinase I gamma 2 Residual Activity 82.0 % 10.1042/bj20121418
Homo sapiens Casein kinase II Residual Activity 73.0 % 10.1042/bj20121418
Homo sapiens Casein kinase II Residual Activity 97.0 % 10.1042/bj20121418
Homo sapiens Casein kinase II alpha Kd 250.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase II alpha Kd 250.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase II alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase II alpha (prime) Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase II alpha (prime) Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase II alpha (prime) Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase II alpha (prime) Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase II alpha (prime) Residual Activity 102.0 % 10.1042/bj20121418
Homo sapiens Casein kinase II alpha (prime) Residual Activity 117.0 % 10.1042/bj20121418
Homo sapiens Casein kinase I isoform alpha-like Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I isoform alpha-like Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I isoform gamma-3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I isoform gamma-3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I isoform gamma-3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Casein kinase I isoform gamma-3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I isoform gamma-3 Residual Activity 14.0 % 10.1042/bj20121418
Homo sapiens Casein kinase I isoform gamma-3 Residual Activity 66.0 % 10.1042/bj20121418
Homo sapiens Ca-Ski IC50 18534.28 nM 10.6019/CHEMBL1201861
Homo sapiens CCF-STTG1 IC50 253.35 nM 10.6019/CHEMBL1201861
Homo sapiens CCRF-CEM IC50 470.81 nM 10.6019/CHEMBL1201861
Homo sapiens CDK3/cyclin E Residual Activity 67.0 % 10.1042/bj20121418
Homo sapiens CDK3/cyclin E Residual Activity 76.0 % 10.1042/bj20121418
Homo sapiens CDK6/cyclin D3 Residual Activity 81.0 % 10.1042/bj20121418
Homo sapiens CDK6/cyclin D3 Residual Activity 87.0 % 10.1042/bj20121418
Homo sapiens CDK9/cyclin T1 Residual Activity 58.0 % 10.1042/bj20121418
Homo sapiens CDK9/cyclin T1 Residual Activity 70.0 % 10.1042/bj20121418
Homo sapiens Cell division cycle 2-like protein kinase 6 Kd 7200.0 nM 10.1038/nbt1358
Homo sapiens Cell division cycle 2-like protein kinase 6 Kd 7200.0 nM 10.1038/nbt.1990
Homo sapiens Cell division cycle 2-like protein kinase 6 Kd 7200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cell division protein kinase 8 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cell division protein kinase 8 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cell division protein kinase 8 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CESS IC50 1819.1 nM 10.6019/CHEMBL1201861
Homo sapiens cGMP-dependent protein kinase 1 beta Kd 250.0 nM 10.1038/nbt1358
Homo sapiens cGMP-dependent protein kinase 1 beta Kd 250.0 nM 10.1038/nbt.1990
Homo sapiens cGMP-dependent protein kinase 1 beta Kd 250.0 nM 10.1182/blood-2009-05-222034
Homo sapiens cGMP-dependent protein kinase 1 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cGMP-dependent protein kinase 1 beta Residual Activity 3.0 % 10.1042/bj20121418
Homo sapiens cGMP-dependent protein kinase 1 beta Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens cGMP-dependent protein kinase 1 beta Residual Activity 8.0 % 10.1042/bj20121418
Homo sapiens cGMP-dependent protein kinase 2 Kd 74.0 nM 10.1038/nbt1358
Homo sapiens cGMP-dependent protein kinase 2 Kd 74.0 nM 10.1038/nbt.1990
Homo sapiens cGMP-dependent protein kinase 2 Kd 74.0 nM 10.1182/blood-2009-05-222034
Homo sapiens CGTH-W-1 IC50 42.65 nM 10.6019/CHEMBL1201861
Homo sapiens ChaGo-K-1 IC50 2898.15 nM 10.6019/CHEMBL1201861
Homo sapiens Chaperone activity of bc1 complex-like, mitochondrial Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Chaperone activity of bc1 complex-like, mitochondrial Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Chaperone activity of bc1 complex-like, mitochondrial Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Chaperone activity of bc1 complex-like, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens CHL-1 IC50 7955.1 nM 10.6019/CHEMBL1201861
Homo sapiens CHP-126 IC50 4844.68 nM 10.6019/CHEMBL1201861
Homo sapiens CHP-212 IC50 87.73 nM 10.6019/CHEMBL1201861
Homo sapiens Citron Rho-interacting kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Citron Rho-interacting kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Citron Rho-interacting kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Citron Rho-interacting kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens c-Jun N-terminal kinase 1 Kd 4400.0 nM 10.1038/nbt1358
Homo sapiens c-Jun N-terminal kinase 1 Kd 4400.0 nM 10.1038/nbt.1990
Homo sapiens c-Jun N-terminal kinase 1 Kd 4400.0 nM 10.1182/blood-2009-05-222034
Homo sapiens c-Jun N-terminal kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens c-Jun N-terminal kinase 1 Residual Activity 67.0 % 10.1042/bj20121418
Homo sapiens c-Jun N-terminal kinase 1 Residual Activity 92.0 % 10.1042/bj20121418
Homo sapiens c-Jun N-terminal kinase 2 Kd 5000.0 nM 10.1038/nbt.1990
Homo sapiens c-Jun N-terminal kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens c-Jun N-terminal kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens c-Jun N-terminal kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens c-Jun N-terminal kinase 2 Residual Activity 91.0 % 10.1042/bj20121418
Homo sapiens c-Jun N-terminal kinase 2 Residual Activity 99.0 % 10.1042/bj20121418
Homo sapiens c-Jun N-terminal kinase 3 Kd 3600.0 nM 10.1038/nbt1358
Homo sapiens c-Jun N-terminal kinase 3 Kd 3600.0 nM 10.1038/nbt.1990
Homo sapiens c-Jun N-terminal kinase 3 Kd 3600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens c-Jun N-terminal kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens c-Jun N-terminal kinase 3 Residual Activity 27.0 % 10.1042/bj20121418
Homo sapiens c-Jun N-terminal kinase 3 Residual Activity 50.0 % 10.1042/bj20121418
Homo sapiens CMK IC50 1090.82 nM 10.6019/CHEMBL1201861
Homo sapiens COLO 205 IC50 432.22 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-320-HSR IC50 4646.56 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-668 IC50 1122.32 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-678 IC50 2734.77 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-679 IC50 4166.29 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-680N IC50 471.06 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-684 IC50 3347.45 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-741 IC50 55315.44 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-792 IC50 299.72 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-800 IC50 1403.6 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-824 IC50 2884.33 nM 10.6019/CHEMBL1201861
Homo sapiens COLO-829 IC50 11619.17 nM 10.6019/CHEMBL1201861
Homo sapiens COR-L105 IC50 370.71 nM 10.6019/CHEMBL1201861
Homo sapiens COR-L23 IC50 11187.82 nM 10.6019/CHEMBL1201861
Homo sapiens COR-L279 IC50 3563.57 nM 10.6019/CHEMBL1201861
Homo sapiens COR-L88 IC50 9600.55 nM 10.6019/CHEMBL1201861
Homo sapiens CP50-MEL-B IC50 14628.72 nM 10.6019/CHEMBL1201861
Homo sapiens CP66-MEL IC50 40603.04 nM 10.6019/CHEMBL1201861
Homo sapiens CPC-N IC50 91188.7 nM 10.6019/CHEMBL1201861
Homo sapiens CTB-1 IC50 1486.0 nM 10.6019/CHEMBL1201861
Homo sapiens CTV-1 IC50 2016.35 nM 10.6019/CHEMBL1201861
Homo sapiens CW-2 IC50 89273.62 nM 10.6019/CHEMBL1201861
Homo sapiens CWR22R IC50 9723.82 nM 10.6019/CHEMBL1201861
Homo sapiens Cyclin-dependent kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 12 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 13 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 13 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 1/cyclin B1 Residual Activity 80.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 1/cyclin B1 Residual Activity 82.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 2/cyclin A Residual Activity 39.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 2/cyclin A Residual Activity 80.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 2/cyclin E Residual Activity 60.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 2/cyclin E Residual Activity 70.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 5/CDK5 activator 1 IC50 10000.0 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Cyclin-dependent kinase 5/CDK5 activator 1 Residual Activity 40.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 5/CDK5 activator 1 Residual Activity 54.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 5/CDK5 activator 1 Residual Activity 57.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 5/CDK5 activator 1 Residual Activity 76.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 7 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase 7 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 7/ cyclin H Residual Activity 84.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 7/ cyclin H Residual Activity 90.0 % 10.1042/bj20121418
Homo sapiens Cyclin-dependent kinase 9 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 9 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 9 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase 9 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase-like 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase-like 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase-like 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase-like 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase-like 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase-like 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase-like 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Cyclin-dependent kinase-like 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cytochrome c1, heme protein, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens D-247MG IC50 250.13 nM 10.6019/CHEMBL1201861
Homo sapiens D-263MG IC50 414.13 nM 10.6019/CHEMBL1201861
Homo sapiens D283 Med IC50 20731.37 nM 10.6019/CHEMBL1201861
Homo sapiens D-336MG IC50 87.54 nM 10.6019/CHEMBL1201861
Homo sapiens D-392MG IC50 331.2 nM 10.6019/CHEMBL1201861
Homo sapiens D-502MG IC50 5842.31 nM 10.6019/CHEMBL1201861
Homo sapiens D-542MG IC50 23139.57 nM 10.6019/CHEMBL1201861
Homo sapiens Daoy IC50 1335.7 nM 10.6019/CHEMBL1201861
Homo sapiens Daudi IC50 5091.19 nM 10.6019/CHEMBL1201861
Homo sapiens DB IC50 1219.29 nM 10.6019/CHEMBL1201861
Homo sapiens DBTRG-05MG IC50 941.97 nM 10.6019/CHEMBL1201861
Homo sapiens dCTP pyrophosphatase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Death-associated protein kinase 1 Kd 4700.0 nM 10.1038/nbt1358
Homo sapiens Death-associated protein kinase 1 Kd 4700.0 nM 10.1038/nbt.1990
Homo sapiens Death-associated protein kinase 1 Kd 4700.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Death-associated protein kinase 1 Residual Activity 63.0 % 10.1042/bj20121418
Homo sapiens Death-associated protein kinase 1 Residual Activity 72.0 % 10.1042/bj20121418
Homo sapiens Death-associated protein kinase 2 Kd 890.0 nM 10.1038/nbt1358
Homo sapiens Death-associated protein kinase 2 Kd 890.0 nM 10.1038/nbt.1990
Homo sapiens Death-associated protein kinase 2 Kd 890.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Death-associated protein kinase 2 Residual Activity 54.0 % 10.1042/bj20121418
Homo sapiens Death-associated protein kinase 2 Residual Activity 71.0 % 10.1042/bj20121418
Homo sapiens Death-associated protein kinase 3 Kd 1800.0 nM 10.1038/nbt1358
Homo sapiens Death-associated protein kinase 3 Kd 1800.0 nM 10.1038/nbt.1990
Homo sapiens Death-associated protein kinase 3 Kd 1800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Death-associated protein kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Death-associated protein kinase 3 Residual Activity 56.0 % 10.1042/bj20121418
Homo sapiens Death-associated protein kinase 3 Residual Activity 59.0 % 10.1042/bj20121418
Homo sapiens DEL IC50 558.98 nM 10.6019/CHEMBL1201861
Homo sapiens Delta(24)-sterol reductase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Deoxycytidine kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Detroit 562 IC50 5667.65 nM 10.6019/CHEMBL1201861
Homo sapiens DG-75 IC50 57207.61 nM 10.6019/CHEMBL1201861
Homo sapiens Discoidin domain-containing receptor 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Discoidin domain-containing receptor 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Discoidin domain-containing receptor 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Discoidin domain-containing receptor 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Discoidin domain-containing receptor 2 Residual Activity 69.0 % 10.1042/bj20121418
Homo sapiens Discoidin domain-containing receptor 2 Residual Activity 106.0 % 10.1042/bj20121418
Homo sapiens DJM-1 IC50 14554.88 nM 10.6019/CHEMBL1201861
Homo sapiens DK-MG IC50 1580.48 nM 10.6019/CHEMBL1201861
Homo sapiens DMS-114 IC50 119770.93 nM 10.6019/CHEMBL1201861
Homo sapiens DMS-153 IC50 18016.64 nM 10.6019/CHEMBL1201861
Homo sapiens DMS-273 IC50 323.88 nM 10.6019/CHEMBL1201861
Homo sapiens DMS-53 IC50 32103.47 nM 10.6019/CHEMBL1201861
Homo sapiens DMS-79 IC50 66101.07 nM 10.6019/CHEMBL1201861
Homo sapiens DnaJ homolog subfamily A member 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DNA replication licensing factor MCM4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DNA topoisomerase II alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DNA topoisomerase II beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DOHH-2 IC50 38935.13 nM 10.6019/CHEMBL1201861
Homo sapiens DOK IC50 636.7 nM 10.6019/CHEMBL1201861
Homo sapiens DoTc2-4510 IC50 290.02 nM 10.6019/CHEMBL1201861
Homo sapiens DSH1 IC50 1023.89 nM 10.6019/CHEMBL1201861
Homo sapiens DU-145 IC50 318.89 nM 10.6019/CHEMBL1201861
Homo sapiens DU-4475 IC50 3871.34 nM 10.6019/CHEMBL1201861
Homo sapiens Dual serine/threonine and tyrosine protein kinase Kd 4700.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Residual Activity 56.0 % 10.1042/bj20121418
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Residual Activity 74.0 % 10.1042/bj20121418
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Kd 5300.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Kd 5300.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Kd 5300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 4 Kd 4800.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 4 Kd 4800.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 4 Kd 4800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Kd 6500.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Residual Activity 52.0 % 10.1042/bj20121418
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Residual Activity 58.0 % 10.1042/bj20121418
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 7 Residual Activity 111.0 % 10.1042/bj20121418
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 7 Residual Activity 135.0 % 10.1042/bj20121418
Homo sapiens Dual specificity protein kinase CLK2 IC50 2979.0 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Dual specificity protein kinase CLK2 Kd 860.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase CLK2 Kd 860.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase CLK2 Kd 860.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity protein kinase CLK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity protein kinase CLK2 Residual Activity 9.0 % 10.1042/bj20121418
Homo sapiens Dual specificity protein kinase CLK2 Residual Activity 17.0 % 10.1042/bj20121418
Homo sapiens Dual specificity protein kinase CLK3 IC50 10000.0 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Dual specificity protein kinase CLK3 Kd 3600.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase CLK3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase CLK3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity protein kinase CLK3 Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens Dual specificity protein kinase CLK3 Residual Activity 51.0 % 10.1042/bj20121418
Homo sapiens Dual specificity protein kinase CLK4 IC50 1555.0 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Dual specificity protein kinase CLK4 Kd 410.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase CLK4 Kd 410.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase CLK4 Kd 410.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity protein kinase CLK4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity protein kinase TTK Kd 350.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase TTK Kd 350.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase TTK Kd 350.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity testis-specific protein kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity testis-specific protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity testis-specific protein kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificity testis-specific protein kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A IC50 886.5 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A Kd 100.0 nM 10.1038/nbt.1990
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A Kd 100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B IC50 2035.0 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B Kd 330.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B Kd 330.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B Kd 330.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 2 IC50 10000.0 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 2 Residual Activity 88.0 % 10.1042/bj20121418
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 2 Residual Activity 90.0 % 10.1042/bj20121418
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 3 IC50 10000.0 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 4 IC50 10000.0 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Dual specificty protein kinase CLK1 IC50 1367.0 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Dual specificty protein kinase CLK1 Kd 350.0 nM 10.1038/nbt1358
Homo sapiens Dual specificty protein kinase CLK1 Kd 350.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificty protein kinase CLK1 Kd 350.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Dual specificty protein kinase CLK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DV-90 IC50 2242.15 nM 10.6019/CHEMBL1201861
Homo sapiens Dynamin-like 120 kDa protein, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens EB2 IC50 11996.82 nM 10.6019/CHEMBL1201861
Homo sapiens EB-3 IC50 5597.68 nM 10.6019/CHEMBL1201861
Homo sapiens ECC12 IC50 429.23 nM 10.6019/CHEMBL1201861
Homo sapiens ECC4 IC50 1261.82 nM 10.6019/CHEMBL1201861
Homo sapiens EC-GI-10 IC50 46746.39 nM 10.6019/CHEMBL1201861
Homo sapiens EFE-184 IC50 473.46 nM 10.6019/CHEMBL1201861
Homo sapiens EFM-19 IC50 212.13 nM 10.6019/CHEMBL1201861
Homo sapiens EFO-21 IC50 129.72 nM 10.6019/CHEMBL1201861
Homo sapiens EFO-27 IC50 525.24 nM 10.6019/CHEMBL1201861
Homo sapiens EGI-1 IC50 1300.89 nM 10.6019/CHEMBL1201861
Homo sapiens EHEB IC50 5112.24 nM 10.6019/CHEMBL1201861
Homo sapiens EKVX IC50 14513.55 nM 10.6019/CHEMBL1201861
Homo sapiens Electron transfer flavoprotein subunit beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Elongation factor Tu, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens EM-2 IC50 1565.54 nM 10.6019/CHEMBL1201861
Homo sapiens EOL1 Activity nan None 10.1021/acs.jnatprod.7b01079
Homo sapiens EOL1 IC50 3.8 nM 10.1021/acs.jnatprod.7b01079
Homo sapiens EOL1 IC50 52.08 nM 10.6019/CHEMBL1201861
Homo sapiens Ephrin type-A receptor 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 1 Residual Activity 81.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 1 Residual Activity 87.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 2 Residual Activity 95.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 2 Residual Activity 97.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 3 Residual Activity 97.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 3 Residual Activity 99.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 4 Residual Activity 90.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 4 Residual Activity 103.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 5 Residual Activity 86.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 5 Residual Activity 97.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 7 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 7 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 7 Residual Activity 70.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 7 Residual Activity 94.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 8 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 8 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 8 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-A receptor 8 Residual Activity 94.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-A receptor 8 Residual Activity 97.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-B receptor 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-B receptor 1 Residual Activity 78.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-B receptor 1 Residual Activity 97.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-B receptor 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-B receptor 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-B receptor 2 Residual Activity 111.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-B receptor 2 Residual Activity 222.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-B receptor 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-B receptor 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-B receptor 3 Residual Activity 119.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-B receptor 3 Residual Activity 130.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-B receptor 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-B receptor 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-B receptor 4 Residual Activity 107.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-B receptor 4 Residual Activity 372.0 % 10.1042/bj20121418
Homo sapiens Ephrin type-B receptor 6 Kd 3100.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 6 Kd 3100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ephrin type-B receptor 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Epidermal growth factor receptor erbB1 Kd 8.8 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 9.8 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 26.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Epidermal growth factor receptor erbB1 Kd 620.0 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 620.0 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 760.0 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 760.0 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 760.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1300.0 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1300.0 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1500.0 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1500.0 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1500.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1700.0 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1700.0 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1800.0 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1800.0 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1900.0 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1900.0 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 2800.0 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 2800.0 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 2800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Epidermal growth factor receptor erbB1 Kd 5300.0 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 5300.0 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 5300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Epidermal growth factor receptor erbB1 Kd 7000.0 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 7000.0 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Epidermal growth factor receptor erbB1 Residual Activity 98.0 % 10.1042/bj20121418
Homo sapiens Epidermal growth factor receptor erbB1 Residual Activity 101.0 % 10.1042/bj20121418
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 7200.0 nM 10.1038/nbt1358
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 7200.0 nM 10.1038/nbt.1990
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 7200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ES1 IC50 12086.2 nM 10.6019/CHEMBL1201861
Homo sapiens ES3 IC50 4055.57 nM 10.6019/CHEMBL1201861
Homo sapiens ES4 IC50 1164.62 nM 10.6019/CHEMBL1201861
Homo sapiens ES5 IC50 1329.81 nM 10.6019/CHEMBL1201861
Homo sapiens ES6 IC50 4106.66 nM 10.6019/CHEMBL1201861
Homo sapiens ES7 IC50 1538.48 nM 10.6019/CHEMBL1201861
Homo sapiens ES8 IC50 1223.04 nM 10.6019/CHEMBL1201861
Homo sapiens ESS-1 IC50 1076.18 nM 10.6019/CHEMBL1201861
Homo sapiens ETK-1 IC50 376.93 nM 10.6019/CHEMBL1201861
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 1 Kd 2047.0 nM 10.1126/science.aan4368
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 4 Kd 39.0 nM 10.1038/nbt1358
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 4 Kd 39.0 nM 10.1038/nbt.1990
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 4 Kd 39.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Eukaryotic translation initiation factor 5B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens EVSA-T IC50 42895.37 nM 10.6019/CHEMBL1201861
Homo sapiens EW-1 IC50 531.55 nM 10.6019/CHEMBL1201861
Homo sapiens EW-11 IC50 32924.79 nM 10.6019/CHEMBL1201861
Homo sapiens EW-13 IC50 435.48 nM 10.6019/CHEMBL1201861
Homo sapiens EW-16 IC50 314.3 nM 10.6019/CHEMBL1201861
Homo sapiens EW-18 IC50 322.33 nM 10.6019/CHEMBL1201861
Homo sapiens EW-24 IC50 21296.04 nM 10.6019/CHEMBL1201861
Homo sapiens EW-3 IC50 6498.26 nM 10.6019/CHEMBL1201861
Homo sapiens EW-7 IC50 681.95 nM 10.6019/CHEMBL1201861
Homo sapiens Exosome RNA helicase MTR4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens FaDu IC50 1185.47 nM 10.6019/CHEMBL1201861
Homo sapiens Ferrochelatase, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Fibroblast growth factor receptor 1 Kd 1600.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 1 Kd 1600.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 1 Kd 1600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Fibroblast growth factor receptor 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Fibroblast growth factor receptor 1 Residual Activity -4.0 % 10.1042/bj20121418
Homo sapiens Fibroblast growth factor receptor 1 Residual Activity 5.0 % 10.1042/bj20121418
Homo sapiens Fibroblast growth factor receptor 2 Kd 2400.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 2 Kd 2400.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 2 Kd 2400.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Fibroblast growth factor receptor 2 Residual Activity 7.0 % 10.1042/bj20121418
Homo sapiens Fibroblast growth factor receptor 2 Residual Activity 21.0 % 10.1042/bj20121418
Homo sapiens Fibroblast growth factor receptor 3 Kd 1700.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 3 Kd 1700.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 3 Kd 1700.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Fibroblast growth factor receptor 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Fibroblast growth factor receptor 3 Residual Activity 19.0 % 10.1042/bj20121418
Homo sapiens Fibroblast growth factor receptor 3 Residual Activity 34.0 % 10.1042/bj20121418
Homo sapiens Fibroblast growth factor receptor 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Fibroblast growth factor receptor 4 Residual Activity 41.0 % 10.1042/bj20121418
Homo sapiens Fibroblast growth factor receptor 4 Residual Activity 71.0 % 10.1042/bj20121418
Homo sapiens Focal adhesion kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Focal adhesion kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Focal adhesion kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Focal adhesion kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Focal adhesion kinase 1 Residual Activity 37.0 % 10.1042/bj20121418
Homo sapiens Focal adhesion kinase 1 Residual Activity 90.0 % 10.1042/bj20121418
Homo sapiens FTC-133 IC50 25665.76 nM 10.6019/CHEMBL1201861
Homo sapiens G-361 IC50 208.53 nM 10.6019/CHEMBL1201861
Homo sapiens G-401 IC50 223.39 nM 10.6019/CHEMBL1201861
Homo sapiens G-402 IC50 202.53 nM 10.6019/CHEMBL1201861
Homo sapiens GAK IC50 11334.76 nM 10.6019/CHEMBL1201861
Homo sapiens GAMG IC50 1178.66 nM 10.6019/CHEMBL1201861
Homo sapiens GB-1 IC50 560.07 nM 10.6019/CHEMBL1201861
Homo sapiens GCIY IC50 286.92 nM 10.6019/CHEMBL1201861
Homo sapiens GCT IC50 528.97 nM 10.6019/CHEMBL1201861
Homo sapiens GDM-1 IC50 172.62 nM 10.6019/CHEMBL1201861
Homo sapiens General transcription and DNA repair factor IIH helicase subunit XPD Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens GI-1 IC50 319.02 nM 10.6019/CHEMBL1201861
Homo sapiens GI-ME-N IC50 194.75 nM 10.6019/CHEMBL1201861
Homo sapiens GISTT1 GI50 235.0 nM 10.1021/acs.jmedchem.9b01229
Homo sapiens Glycine--tRNA ligase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Glycogen synthase kinase-3 alpha Kd 2500.0 nM 10.1038/nbt1358
Homo sapiens Glycogen synthase kinase-3 alpha Kd 2500.0 nM 10.1038/nbt.1990
Homo sapiens Glycogen synthase kinase-3 alpha Kd 2500.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Glycogen synthase kinase-3 alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Glycogen synthase kinase-3 alpha Residual Activity 14.0 % 10.1042/bj20121418
Homo sapiens Glycogen synthase kinase-3 alpha Residual Activity 17.0 % 10.1042/bj20121418
Homo sapiens Glycogen synthase kinase-3 beta IC50 4636.0 nM 10.1021/acs.jmedchem.2c02068
Homo sapiens Glycogen synthase kinase-3 beta Kd 1800.0 nM 10.1038/nbt1358
Homo sapiens Glycogen synthase kinase-3 beta Kd 1800.0 nM 10.1038/nbt.1990
Homo sapiens Glycogen synthase kinase-3 beta Kd 1800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Glycogen synthase kinase-3 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Glycogen synthase kinase-3 beta Residual Activity 19.0 % 10.1042/bj20121418
Homo sapiens Glycogen synthase kinase-3 beta Residual Activity 39.0 % 10.1042/bj20121418
Homo sapiens GMS-10 IC50 1538.37 nM 10.6019/CHEMBL1201861
Homo sapiens GOTO IC50 1958.32 nM 10.6019/CHEMBL1201861
Homo sapiens GP5d IC50 2075.34 nM 10.6019/CHEMBL1201861
Homo sapiens G-protein coupled receptor kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens G protein-coupled receptor kinase 4 Kd 110.0 nM 10.1038/nbt.1990
Homo sapiens G protein-coupled receptor kinase 4 Kd 110.0 nM 10.1182/blood-2009-05-222034
Homo sapiens G protein-coupled receptor kinase 5 Residual Activity 74.0 % 10.1042/bj20121418
Homo sapiens G protein-coupled receptor kinase 5 Residual Activity 82.0 % 10.1042/bj20121418
Homo sapiens G protein-coupled receptor kinase 6 Residual Activity 70.0 % 10.1042/bj20121418
Homo sapiens G protein-coupled receptor kinase 6 Residual Activity 79.0 % 10.1042/bj20121418
Homo sapiens G protein-coupled receptor kinase 7 Kd 48.0 nM 10.1038/nbt.1990
Homo sapiens G protein-coupled receptor kinase 7 Kd 48.0 nM 10.1182/blood-2009-05-222034
Homo sapiens G protein-coupled receptor kinase 7 Residual Activity 3.0 % 10.1042/bj20121418
Homo sapiens G protein-coupled receptor kinase 7 Residual Activity 8.0 % 10.1042/bj20121418
Homo sapiens GR-ST IC50 872.37 nM 10.6019/CHEMBL1201861
Homo sapiens GT3TKB IC50 380.43 nM 10.6019/CHEMBL1201861
Homo sapiens GTP-binding nuclear protein Ran Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Guanine nucleotide-binding protein G(i) subunit alpha-2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens H4 IC50 139.63 nM 10.6019/CHEMBL1201861
Homo sapiens HAL-01 IC50 8744.13 nM 10.6019/CHEMBL1201861
Homo sapiens HC-1 IC50 2895.29 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1143 IC50 41676.4 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1187 IC50 7907.46 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1395 IC50 84.28 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1419 IC50 31505.62 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1569 IC50 1170.18 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1599 IC50 879.1 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1806 IC50 1530.72 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1937 IC50 24650.91 nM 10.6019/CHEMBL1201861
Homo sapiens HCC1954 IC50 37406.26 nM 10.6019/CHEMBL1201861
Homo sapiens HCC2157 IC50 1738.98 nM 10.6019/CHEMBL1201861
Homo sapiens HCC2218 IC50 83052.84 nM 10.6019/CHEMBL1201861
Homo sapiens HCC 2998 IC50 11425.14 nM 10.6019/CHEMBL1201861
Homo sapiens HCC38 IC50 498.28 nM 10.6019/CHEMBL1201861
Homo sapiens HCC70 IC50 2449.49 nM 10.6019/CHEMBL1201861
Homo sapiens HCE-4 IC50 410.1 nM 10.6019/CHEMBL1201861
Homo sapiens HCE-T IC50 1934.51 nM 10.6019/CHEMBL1201861
Homo sapiens HCT-116 IC50 235.68 nM 10.6019/CHEMBL1201861
Homo sapiens HCT-15 IC50 334.32 nM 10.6019/CHEMBL1201861
Homo sapiens HDLM-2 IC50 13737.55 nM 10.6019/CHEMBL1201861
Homo sapiens HD-MY-Z IC50 60103.07 nM 10.6019/CHEMBL1201861
Homo sapiens HEC-1 IC50 4394.33 nM 10.6019/CHEMBL1201861
Homo sapiens HEL IC50 985.17 nM 10.6019/CHEMBL1201861
Homo sapiens Heme oxygenase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Hepatocyte growth factor receptor Kd 560.0 nM 10.1038/nbt.1990
Homo sapiens Hepatocyte growth factor receptor Kd 560.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Hepatocyte growth factor receptor Kd 690.0 nM 10.1038/nbt1358
Homo sapiens Hepatocyte growth factor receptor Kd 690.0 nM 10.1038/nbt.1990
Homo sapiens Hepatocyte growth factor receptor Kd 690.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Hepatocyte growth factor receptor Kd 2100.0 nM 10.1038/nbt.1990
Homo sapiens Hepatocyte growth factor receptor Kd 2100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Hepatocyte growth factor receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Hepatocyte growth factor receptor Residual Activity 35.0 % 10.1042/bj20121418
Homo sapiens Hepatocyte growth factor receptor Residual Activity 40.0 % 10.1042/bj20121418
Homo sapiens HepG2 IC50 relative 1900.0 nM 10.6019/EOS300108
Homo sapiens HGC-27 IC50 3229.9 nM 10.6019/CHEMBL1201861
Homo sapiens HH IC50 4893.03 nM 10.6019/CHEMBL1201861
Homo sapiens Histone deacetylase 6 Inhibition -23.2 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition -9.74 % 10.6019/CHEMBL4808148
Homo sapiens HL-60 IC50 500.0 nM 10.1021/acs.jmedchem.1c02079
Homo sapiens HL-60 IC50 10000.0 nM 10.1021/acs.jnatprod.9b00468
Homo sapiens HL-60 IC50 22590.13 nM 10.6019/CHEMBL1201861
Homo sapiens HLE IC50 337.52 nM 10.6019/CHEMBL1201861
Homo sapiens HMV-2 cell line IC50 1793.86 nM 10.6019/CHEMBL1201861
Homo sapiens HN IC50 6990.41 nM 10.6019/CHEMBL1201861
Homo sapiens HO-1-N-1 IC50 3155.69 nM 10.6019/CHEMBL1201861
Homo sapiens Homeodomain-interacting protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Homeodomain-interacting protein kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Homeodomain-interacting protein kinase 1 Residual Activity 83.0 % 10.1042/bj20121418
Homo sapiens Homeodomain-interacting protein kinase 1 Residual Activity 95.0 % 10.1042/bj20121418
Homo sapiens Homeodomain-interacting protein kinase 2 Kd 3100.0 nM 10.1038/nbt.1990
Homo sapiens Homeodomain-interacting protein kinase 2 Kd 3100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Homeodomain-interacting protein kinase 2 Residual Activity 35.0 % 10.1042/bj20121418
Homo sapiens Homeodomain-interacting protein kinase 2 Residual Activity 75.0 % 10.1042/bj20121418
Homo sapiens Homeodomain-interacting protein kinase 3 Kd 2300.0 nM 10.1038/nbt.1990
Homo sapiens Homeodomain-interacting protein kinase 3 Kd 2300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Homeodomain-interacting protein kinase 3 Residual Activity 68.0 % 10.1042/bj20121418
Homo sapiens Homeodomain-interacting protein kinase 3 Residual Activity 80.0 % 10.1042/bj20121418
Homo sapiens Homeodomain-interacting protein kinase 4 Kd 950.0 nM 10.1038/nbt.1990
Homo sapiens Homeodomain-interacting protein kinase 4 Kd 950.0 nM 10.1182/blood-2009-05-222034
Homo sapiens HOP-62 IC50 180.73 nM 10.6019/CHEMBL1201861
Homo sapiens HOP-92 IC50 698.65 nM 10.6019/CHEMBL1201861
Homo sapiens Hormonally up-regulated neu tumor-associated kinase Kd 240.0 nM 10.1038/nbt.1990
Homo sapiens Hormonally up-regulated neu tumor-associated kinase Kd 240.0 nM 10.1182/blood-2009-05-222034
Homo sapiens HOS IC50 458.88 nM 10.6019/CHEMBL1201861
Homo sapiens HPAF-II IC50 19487.09 nM 10.6019/CHEMBL1201861
Homo sapiens Hs-578T IC50 2307.09 nM 10.6019/CHEMBL1201861
Homo sapiens HSC-2 IC50 247.34 nM 10.6019/CHEMBL1201861
Homo sapiens HSC-3 IC50 1816.75 nM 10.6019/CHEMBL1201861
Homo sapiens HSC-4 IC50 4403.37 nM 10.6019/CHEMBL1201861
Homo sapiens HT IC50 27139.55 nM 10.6019/CHEMBL1201861
Homo sapiens HT-1080 IC50 159.82 nM 10.6019/CHEMBL1201861
Homo sapiens HT1197 IC50 30493.73 nM 10.6019/CHEMBL1201861
Homo sapiens HT-1376 IC50 929.18 nM 10.6019/CHEMBL1201861
Homo sapiens HT-144 IC50 389.48 nM 10.6019/CHEMBL1201861
Homo sapiens HT-29 IC50 979.96 nM 10.6019/CHEMBL1201861
Homo sapiens HT-3 IC50 7102.61 nM 10.6019/CHEMBL1201861
Homo sapiens HT55 IC50 2773.21 nM 10.6019/CHEMBL1201861
Homo sapiens HTC-C3 IC50 1640.35 nM 10.6019/CHEMBL1201861
Homo sapiens HuCCT-1 IC50 178.56 nM 10.6019/CHEMBL1201861
Homo sapiens Huh-7 IC50 2789.23 nM 10.6019/CHEMBL1201861
Homo sapiens HuO-3N1 IC50 154.63 nM 10.6019/CHEMBL1201861
Homo sapiens HuO9 IC50 441.35 nM 10.6019/CHEMBL1201861
Homo sapiens HuP-T3 IC50 3207.9 nM 10.6019/CHEMBL1201861
Homo sapiens HuP-T4 IC50 34944.18 nM 10.6019/CHEMBL1201861
Homo sapiens HuTu80 IC50 172.79 nM 10.6019/CHEMBL1201861
Homo sapiens IA-LM IC50 4706.35 nM 10.6019/CHEMBL1201861
Homo sapiens IGR-1 IC50 393.69 nM 10.6019/CHEMBL1201861
Homo sapiens IGROV-1 IC50 1693.17 nM 10.6019/CHEMBL1201861
Homo sapiens IM-9 IC50 2105.17 nM 10.6019/CHEMBL1201861
Homo sapiens IMR-5 IC50 2714.65 nM 10.6019/CHEMBL1201861
Homo sapiens Inhibitor of nuclear factor kappa B kinase alpha subunit Kd 3800.0 nM 10.1038/nbt.1990
Homo sapiens Inhibitor of nuclear factor kappa B kinase alpha subunit Kd 3800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Inhibitor of nuclear factor kappa B kinase alpha subunit Residual Activity 91.0 % 10.1042/bj20121418
Homo sapiens Inhibitor of nuclear factor kappa B kinase alpha subunit Residual Activity 101.0 % 10.1042/bj20121418
Homo sapiens Inhibitor of nuclear factor kappa B kinase beta subunit Kd 6300.0 nM 10.1038/nbt.1990
Homo sapiens Inhibitor of nuclear factor kappa B kinase beta subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Inhibitor of nuclear factor kappa B kinase beta subunit Residual Activity 84.0 % 10.1042/bj20121418
Homo sapiens Inhibitor of nuclear factor kappa B kinase beta subunit Residual Activity 89.0 % 10.1042/bj20121418
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Kd 160.0 nM 10.1038/nbt1358
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Kd 160.0 nM 10.1038/nbt.1990
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Kd 160.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Kd 443.0 nM 10.1126/science.aan4368
Homo sapiens Insulin-like growth factor I receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Insulin-like growth factor I receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Insulin-like growth factor I receptor Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Insulin-like growth factor I receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Insulin-like growth factor I receptor Residual Activity 68.0 % 10.1042/bj20121418
Homo sapiens Insulin-like growth factor I receptor Residual Activity 84.0 % 10.1042/bj20121418
Homo sapiens Insulin-like growth factor I receptor Residual Activity 92.0 % 10.1042/bj20121418
Homo sapiens Insulin-like growth factor I receptor Residual Activity 115.0 % 10.1042/bj20121418
Homo sapiens Insulin receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Insulin receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Insulin receptor Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Insulin receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Insulin receptor Residual Activity 72.0 % 10.1042/bj20121418
Homo sapiens Insulin receptor Residual Activity 80.0 % 10.1042/bj20121418
Homo sapiens Insulin receptor Residual Activity 87.0 % 10.1042/bj20121418
Homo sapiens Insulin receptor Residual Activity 88.0 % 10.1042/bj20121418
Homo sapiens Insulin receptor-related protein Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Insulin receptor-related protein Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Insulin receptor-related protein Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Insulin receptor-related protein Residual Activity 57.0 % 10.1042/bj20121418
Homo sapiens Insulin receptor-related protein Residual Activity 98.0 % 10.1042/bj20121418
Homo sapiens Interferon-induced, double-stranded RNA-activated protein kinase Kd 6900.0 nM 10.1038/nbt1358
Homo sapiens Interferon-induced, double-stranded RNA-activated protein kinase Kd 6900.0 nM 10.1038/nbt.1990
Homo sapiens Interferon-induced, double-stranded RNA-activated protein kinase Kd 6900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Interleukin-1 receptor-associated kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Interleukin-1 receptor-associated kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Interleukin-1 receptor-associated kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Interleukin-1 receptor-associated kinase 1 Residual Activity 74.0 % 10.1042/bj20121418
Homo sapiens Interleukin-1 receptor-associated kinase 1 Residual Activity 85.0 % 10.1042/bj20121418
Homo sapiens Interleukin-1 receptor-associated kinase 3 Kd 180.0 nM 10.1038/nbt1358
Homo sapiens Interleukin-1 receptor-associated kinase 3 Kd 180.0 nM 10.1038/nbt.1990
Homo sapiens Interleukin-1 receptor-associated kinase 3 Kd 180.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Interleukin-1 receptor-associated kinase 3 Kd 3759.0 nM 10.1126/science.aan4368
Homo sapiens Interleukin-1 receptor-associated kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Interleukin-1 receptor-associated kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Interleukin-1 receptor-associated kinase 4 Residual Activity 47.0 % 10.1042/bj20121418
Homo sapiens Interleukin-1 receptor-associated kinase 4 Residual Activity 53.0 % 10.1042/bj20121418
Homo sapiens IPC-298 IC50 3556.72 nM 10.6019/CHEMBL1201861
Homo sapiens IST-MEL1 IC50 2218.3 nM 10.6019/CHEMBL1201861
Homo sapiens IST-MES1 IC50 1560.74 nM 10.6019/CHEMBL1201861
Homo sapiens IST-SL1 IC50 2703.27 nM 10.6019/CHEMBL1201861
Homo sapiens IST-SL2 IC50 6007.53 nM 10.6019/CHEMBL1201861
Homo sapiens J82 IC50 4431.78 nM 10.6019/CHEMBL1201861
Homo sapiens JAR IC50 63845.88 nM 10.6019/CHEMBL1201861
Homo sapiens JEG-3 IC50 12528.1 nM 10.6019/CHEMBL1201861
Homo sapiens JIYOYE IC50 2364.05 nM 10.6019/CHEMBL1201861
Homo sapiens J-RT3-T3-5 IC50 18239.22 nM 10.6019/CHEMBL1201861
Homo sapiens JVM-2 IC50 8220.65 nM 10.6019/CHEMBL1201861
Homo sapiens JVM-3 IC50 66149.35 nM 10.6019/CHEMBL1201861
Homo sapiens K052 IC50 1746.14 nM 10.6019/CHEMBL1201861
Homo sapiens K5 IC50 361.49 nM 10.6019/CHEMBL1201861
Homo sapiens K562 GI50 20000.0 nM 10.1021/acs.jmedchem.9b01229
Homo sapiens K562 IC50 10000.0 nM 10.1021/acs.jnatprod.9b00468
Homo sapiens K562 IC50 14574.68 nM 10.6019/CHEMBL1201861
Homo sapiens KALS-1 IC50 659.03 nM 10.6019/CHEMBL1201861
Homo sapiens KARPAS-299 IC50 94249.73 nM 10.6019/CHEMBL1201861
Homo sapiens KARPAS-422 IC50 59938.68 nM 10.6019/CHEMBL1201861
Homo sapiens KARPAS-45 IC50 4651.65 nM 10.6019/CHEMBL1201861
Homo sapiens Kasumi 1 GI50 284.0 nM 10.1021/acs.jmedchem.9b01229
Homo sapiens Kasumi 1 IC50 60.16 nM 10.6019/CHEMBL1201861
Homo sapiens KE-37 IC50 31963.51 nM 10.6019/CHEMBL1201861
Homo sapiens KG-1 IC50 554.19 nM 10.6019/CHEMBL1201861
Homo sapiens KGN IC50 117.41 nM 10.6019/CHEMBL1201861
Homo sapiens KINGS-1 IC50 2302.71 nM 10.6019/CHEMBL1201861
Homo sapiens KLE IC50 2307.34 nM 10.6019/CHEMBL1201861
Homo sapiens KM12 IC50 92.75 nM 10.6019/CHEMBL1201861
Homo sapiens KM-H2 IC50 9761.9 nM 10.6019/CHEMBL1201861
Homo sapiens KMOE-2 IC50 4797.89 nM 10.6019/CHEMBL1201861
Homo sapiens KMS-12-PE IC50 53824.94 nM 10.6019/CHEMBL1201861
Homo sapiens KNS-42 IC50 12991.83 nM 10.6019/CHEMBL1201861
Homo sapiens KNS-81-FD IC50 5436.17 nM 10.6019/CHEMBL1201861
Homo sapiens KOSC-2 IC50 4399.28 nM 10.6019/CHEMBL1201861
Homo sapiens KP-4 IC50 615.85 nM 10.6019/CHEMBL1201861
Homo sapiens KP-N-YS IC50 24648.79 nM 10.6019/CHEMBL1201861
Homo sapiens KS-1 IC50 130.06 nM 10.6019/CHEMBL1201861
Homo sapiens KU-19-19 IC50 26103.05 nM 10.6019/CHEMBL1201861
Homo sapiens KU812 cell line IC50 1111.64 nM 10.6019/CHEMBL1201861
Homo sapiens KURAMOCHI IC50 1109.35 nM 10.6019/CHEMBL1201861
Homo sapiens KY821 IC50 78363.09 nM 10.6019/CHEMBL1201861
Homo sapiens KYSE-140 IC50 1144.44 nM 10.6019/CHEMBL1201861
Homo sapiens KYSE-150 cell line IC50 262.82 nM 10.6019/CHEMBL1201861
Homo sapiens KYSE-180 IC50 478.25 nM 10.6019/CHEMBL1201861
Homo sapiens KYSE-270 IC50 167.78 nM 10.6019/CHEMBL1201861
Homo sapiens KYSE-410 IC50 312.54 nM 10.6019/CHEMBL1201861
Homo sapiens KYSE-450 IC50 2592.02 nM 10.6019/CHEMBL1201861
Homo sapiens KYSE-510 IC50 785.39 nM 10.6019/CHEMBL1201861
Homo sapiens KYSE-520 cell line IC50 402.38 nM 10.6019/CHEMBL1201861
Homo sapiens KYSE-70 cell line IC50 820.41 nM 10.6019/CHEMBL1201861
Homo sapiens L-363 IC50 5482.79 nM 10.6019/CHEMBL1201861
Homo sapiens L-428 IC50 5838.96 nM 10.6019/CHEMBL1201861
Homo sapiens L-540 IC50 394.54 nM 10.6019/CHEMBL1201861
Homo sapiens LAMA-84 IC50 7266.93 nM 10.6019/CHEMBL1201861
Homo sapiens LAN-6 IC50 56357.14 nM 10.6019/CHEMBL1201861
Homo sapiens LB1047-RCC IC50 154.87 nM 10.6019/CHEMBL1201861
Homo sapiens LB2241-RCC IC50 987.07 nM 10.6019/CHEMBL1201861
Homo sapiens LB2518-MEL IC50 6257.12 nM 10.6019/CHEMBL1201861
Homo sapiens LB373-MEL-D IC50 26439.5 nM 10.6019/CHEMBL1201861
Homo sapiens LB647-SCLC IC50 4225.08 nM 10.6019/CHEMBL1201861
Homo sapiens LB771-HNC IC50 8138.3 nM 10.6019/CHEMBL1201861
Homo sapiens LB831-BLC IC50 299.46 nM 10.6019/CHEMBL1201861
Homo sapiens LB996-RCC IC50 3986.44 nM 10.6019/CHEMBL1201861
Homo sapiens LC-1F IC50 2147.64 nM 10.6019/CHEMBL1201861
Homo sapiens LC-2-ad IC50 113.45 nM 10.6019/CHEMBL1201861
Homo sapiens LC4-1 IC50 4510.96 nM 10.6019/CHEMBL1201861
Homo sapiens LCLC-103H cell line IC50 214.96 nM 10.6019/CHEMBL1201861
Homo sapiens LCLC-97TM1 IC50 753.96 nM 10.6019/CHEMBL1201861
Homo sapiens Leucine-rich repeat serine/threonine-protein kinase 2 Kd 180.0 nM 10.1038/nbt.1990
Homo sapiens Leucine-rich repeat serine/threonine-protein kinase 2 Kd 570.0 nM 10.1038/nbt.1990
Homo sapiens Leukocyte tyrosine kinase receptor Kd 3000.0 nM 10.1038/nbt1358
Homo sapiens Leukocyte tyrosine kinase receptor Kd 3000.0 nM 10.1038/nbt.1990
Homo sapiens Leukocyte tyrosine kinase receptor Kd 3000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens LIM domain kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens LIM domain kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens LIM domain kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens LIM domain kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens LIM domain kinase 1 Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens LIM domain kinase 1 Residual Activity 22.0 % 10.1042/bj20121418
Homo sapiens LIM domain kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens LIM domain kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens LIM domain kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens LIM domain kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Liver glycogen phosphorylase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens LK-2 IC50 3715.52 nM 10.6019/CHEMBL1201861
Homo sapiens LN-405 IC50 54718.62 nM 10.6019/CHEMBL1201861
Homo sapiens LNCaP-Clone-FGC IC50 35335.46 nM 10.6019/CHEMBL1201861
Homo sapiens LOUCY IC50 805.0 nM 10.6019/CHEMBL1201861
Homo sapiens LoVo IC50 4229.85 nM 10.6019/CHEMBL1201861
Homo sapiens LOX IMVI IC50 7988.34 nM 10.6019/CHEMBL1201861
Homo sapiens LP-1 IC50 17506.16 nM 10.6019/CHEMBL1201861
Homo sapiens LS-1034 IC50 905.28 nM 10.6019/CHEMBL1201861
Homo sapiens LS-123 IC50 5637.14 nM 10.6019/CHEMBL1201861
Homo sapiens LS-411N IC50 2749.99 nM 10.6019/CHEMBL1201861
Homo sapiens LS-513 IC50 38311.8 nM 10.6019/CHEMBL1201861
Homo sapiens LU-134-A IC50 5000.07 nM 10.6019/CHEMBL1201861
Homo sapiens LU-139 IC50 8926.15 nM 10.6019/CHEMBL1201861
Homo sapiens LU-165 IC50 4465.13 nM 10.6019/CHEMBL1201861
Homo sapiens Lu-65 IC50 4651.98 nM 10.6019/CHEMBL1201861
Homo sapiens LU-99A IC50 558.49 nM 10.6019/CHEMBL1201861
Homo sapiens LXF-289 cell line IC50 329.65 nM 10.6019/CHEMBL1201861
Homo sapiens M059J IC50 1392.31 nM 10.6019/CHEMBL1201861
Homo sapiens M14 IC50 15845.17 nM 10.6019/CHEMBL1201861
Homo sapiens Macrophage colony stimulating factor receptor Activity 3.0 % 10.1016/j.bmc.2010.01.056
Homo sapiens Macrophage colony stimulating factor receptor Activity 21.0 % 10.1016/j.bmc.2010.01.056
Homo sapiens Macrophage colony stimulating factor receptor Activity 110.0 % 10.1016/j.bmc.2010.01.056
Homo sapiens Macrophage colony stimulating factor receptor IC50 142.0 nM 10.1016/j.bmc.2010.01.056
Homo sapiens Macrophage colony stimulating factor receptor Inhibition nan % 10.1016/j.bmc.2010.01.056
Homo sapiens Macrophage colony stimulating factor receptor Kd 330.0 nM 10.1038/nbt1358
Homo sapiens Macrophage colony stimulating factor receptor Kd 330.0 nM 10.1038/nbt.1990
Homo sapiens Macrophage colony stimulating factor receptor Kd 330.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Macrophage colony stimulating factor receptor logIC50 2.15 None 10.1016/j.bmc.2010.01.056
Homo sapiens Macrophage colony stimulating factor receptor Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens Macrophage colony stimulating factor receptor Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Macrophage-stimulating protein receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Macrophage-stimulating protein receptor Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Macrophage-stimulating protein receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Macrophage-stimulating protein receptor Residual Activity 47.0 % 10.1042/bj20121418
Homo sapiens Macrophage-stimulating protein receptor Residual Activity 56.0 % 10.1042/bj20121418
Homo sapiens MAP kinase-activated protein kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase-activated protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase-activated protein kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase-activated protein kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase-activated protein kinase 2 Residual Activity 47.0 % 10.1042/bj20121418
Homo sapiens MAP kinase-activated protein kinase 2 Residual Activity 75.0 % 10.1042/bj20121418
Homo sapiens MAP kinase-activated protein kinase 3 Residual Activity 37.0 % 10.1042/bj20121418
Homo sapiens MAP kinase-activated protein kinase 3 Residual Activity 68.0 % 10.1042/bj20121418
Homo sapiens MAP kinase-activated protein kinase 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase-activated protein kinase 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase-activated protein kinase 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase-activated protein kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase-activated protein kinase 5 Residual Activity 57.0 % 10.1042/bj20121418
Homo sapiens MAP kinase-activated protein kinase 5 Residual Activity 102.0 % 10.1042/bj20121418
Homo sapiens MAP kinase ERK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase ERK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase ERK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase ERK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase ERK1 Residual Activity 75.0 % 10.1042/bj20121418
Homo sapiens MAP kinase ERK1 Residual Activity 79.0 % 10.1042/bj20121418
Homo sapiens MAP kinase ERK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase ERK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase ERK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase ERK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase ERK2 Residual Activity 98.0 % 10.1042/bj20121418
Homo sapiens MAP kinase ERK2 Residual Activity 101.0 % 10.1042/bj20121418
Homo sapiens MAP kinase-interacting serine/threonine-protein kinase MNK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase-interacting serine/threonine-protein kinase MNK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase-interacting serine/threonine-protein kinase MNK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase p38 alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase p38 alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 alpha Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase p38 alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase p38 alpha Residual Activity 71.0 % 10.1042/bj20121418
Homo sapiens MAP kinase p38 alpha Residual Activity 78.0 % 10.1042/bj20121418
Homo sapiens MAP kinase p38 beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase p38 beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 beta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase p38 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase p38 beta Residual Activity 86.0 % 10.1042/bj20121418
Homo sapiens MAP kinase p38 beta Residual Activity 98.0 % 10.1042/bj20121418
Homo sapiens MAP kinase p38 delta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 delta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase p38 delta Residual Activity 77.0 % 10.1042/bj20121418
Homo sapiens MAP kinase p38 delta Residual Activity 92.0 % 10.1042/bj20121418
Homo sapiens MAP kinase p38 gamma Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase p38 gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 gamma Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase p38 gamma Residual Activity 87.0 % 10.1042/bj20121418
Homo sapiens MAP kinase p38 gamma Residual Activity 104.0 % 10.1042/bj20121418
Homo sapiens MAP kinase signal-integrating kinase 2 Kd 950.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase signal-integrating kinase 2 Kd 950.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase signal-integrating kinase 2 Kd 950.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP kinase signal-integrating kinase 2 Residual Activity 27.0 % 10.1042/bj20121418
Homo sapiens MAP kinase signal-integrating kinase 2 Residual Activity 44.0 % 10.1042/bj20121418
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd 100.0 nM 10.1038/nbt1358
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd 100.0 nM 10.1038/nbt.1990
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd 100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd 759.0 nM 10.1126/science.aan4368
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Residual Activity 2.0 % 10.1042/bj20121418
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Kd 370.0 nM 10.1038/nbt1358
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Kd 370.0 nM 10.1038/nbt.1990
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Kd 370.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Maternal embryonic leucine zipper kinase Kd 280.0 nM 10.1038/nbt1358
Homo sapiens Maternal embryonic leucine zipper kinase Kd 280.0 nM 10.1038/nbt.1990
Homo sapiens Maternal embryonic leucine zipper kinase Kd 280.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Maternal embryonic leucine zipper kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Maternal embryonic leucine zipper kinase Residual Activity 2.0 % 10.1042/bj20121418
Homo sapiens Maternal embryonic leucine zipper kinase Residual Activity 5.0 % 10.1042/bj20121418
Homo sapiens MC116 IC50 715.81 nM 10.6019/CHEMBL1201861
Homo sapiens MC-CAR IC50 3781.33 nM 10.6019/CHEMBL1201861
Homo sapiens MCF7 IC50 332.74 nM 10.6019/CHEMBL1201861
Homo sapiens MC-IXC IC50 266.29 nM 10.6019/CHEMBL1201861
Homo sapiens MDA-MB-134-VI IC50 4791.07 nM 10.6019/CHEMBL1201861
Homo sapiens MDA-MB-157 IC50 420.15 nM 10.6019/CHEMBL1201861
Homo sapiens MDA-MB-175-VII IC50 6599.15 nM 10.6019/CHEMBL1201861
Homo sapiens MDA-MB-231 IC50 281.01 nM 10.6019/CHEMBL1201861
Homo sapiens MDA-MB-361 IC50 29540.85 nM 10.6019/CHEMBL1201861
Homo sapiens MDA-MB-415 IC50 29170.06 nM 10.6019/CHEMBL1201861
Homo sapiens MDA-MB-453 IC50 34226.19 nM 10.6019/CHEMBL1201861
Homo sapiens MDA-MB-468 IC50 13036.65 nM 10.6019/CHEMBL1201861
Homo sapiens ME-180 IC50 17463.22 nM 10.6019/CHEMBL1201861
Homo sapiens MEG-01 IC50 4062.97 nM 10.6019/CHEMBL1201861
Homo sapiens MEL-HO IC50 726.64 nM 10.6019/CHEMBL1201861
Homo sapiens MEL-JUSO IC50 492.14 nM 10.6019/CHEMBL1201861
Homo sapiens MES-SA IC50 75.44 nM 10.6019/CHEMBL1201861
Homo sapiens MeWo IC50 12857.79 nM 10.6019/CHEMBL1201861
Homo sapiens MFE-280 IC50 5395.69 nM 10.6019/CHEMBL1201861
Homo sapiens MFE-296 IC50 1679.51 nM 10.6019/CHEMBL1201861
Homo sapiens MFH-ino IC50 174.55 nM 10.6019/CHEMBL1201861
Homo sapiens MFM-223 IC50 146137.21 nM 10.6019/CHEMBL1201861
Homo sapiens MG-63 IC50 164.37 nM 10.6019/CHEMBL1201861
Homo sapiens MHH-CALL-2 IC50 10016.92 nM 10.6019/CHEMBL1201861
Homo sapiens MHH-ES-1 IC50 249.4 nM 10.6019/CHEMBL1201861
Homo sapiens MHH-NB-11 IC50 3018.78 nM 10.6019/CHEMBL1201861
Homo sapiens MHH-PREB-1 IC50 6099.45 nM 10.6019/CHEMBL1201861
Homo sapiens MIA PaCa-2 IC50 20740.02 nM 10.6019/CHEMBL1201861
Homo sapiens Microtubule-associated serine/threonine-protein kinase 1 Kd 190.0 nM 10.1038/nbt.1990
Homo sapiens Microtubule-associated serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Midasin Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Misshapen-like kinase 1 Kd 170.0 nM 10.1038/nbt.1990
Homo sapiens Misshapen-like kinase 1 Kd 170.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Misshapen-like kinase 1 Residual Activity 18.0 % 10.1042/bj20121418
Homo sapiens Misshapen-like kinase 1 Residual Activity 52.0 % 10.1042/bj20121418
Homo sapiens Mitogen-activated protein kinase 15 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 15 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 15 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase 15 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase 6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase 7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 7 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase 7 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 10 Kd 790.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 10 Kd 790.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 10 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 17.0 nM 10.1021/jm401094t
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 17.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 17.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 790.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 799.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 12 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 13 Kd 2800.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 13 Kd 2800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 15 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 15 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 2 Kd 140.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 2 Kd 140.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 3 Kd 210.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 3 Kd 210.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Residual Activity 75.0 % 10.1042/bj20121418
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Residual Activity 96.0 % 10.1042/bj20121418
Homo sapiens Mitogen-activated protein kinase kinase kinase 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 Kd 130.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 Kd 130.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 Residual Activity 25.0 % 10.1042/bj20121418
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 Residual Activity 39.0 % 10.1042/bj20121418
Homo sapiens Mitogen-activated protein kinase kinase kinase 9 Kd 15.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 9 Kd 15.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 9 Kd 15.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase 9 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 1 Kd 2100.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 1 Kd 2100.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 1 Kd 2100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 2 Kd 2500.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 2 Kd 2500.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 2 Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 2 Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 3 Kd 120.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 3 Kd 120.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 3 Kd 120.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Kd 650.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Kd 650.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Kd 650.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 1100.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 1100.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 1100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mixed lineage kinase 7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mixed lineage kinase 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mixed lineage kinase 7 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Mixed lineage kinase 7 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MKN-1 IC50 884.12 nM 10.6019/CHEMBL1201861
Homo sapiens MKN-28 IC50 1198.16 nM 10.6019/CHEMBL1201861
Homo sapiens MKN-45 IC50 419.31 nM 10.6019/CHEMBL1201861
Homo sapiens MKN-7 IC50 36282.59 nM 10.6019/CHEMBL1201861
Homo sapiens ML-2 IC50 798.59 nM 10.6019/CHEMBL1201861
Homo sapiens MLMA IC50 4460.9 nM 10.6019/CHEMBL1201861
Homo sapiens MMAC-SF IC50 4058.47 nM 10.6019/CHEMBL1201861
Homo sapiens MN-60 IC50 1834.89 nM 10.6019/CHEMBL1201861
Homo sapiens Mo IC50 147085.49 nM 10.6019/CHEMBL1201861
Homo sapiens MOLM-13 Activity nan None 10.1021/acs.jnatprod.7b01079
Homo sapiens MOLM-13 GI50 55.0 nM 10.1021/acs.jmedchem.9b01229
Homo sapiens MOLM-13 IC50 4.7 nM 10.1021/acs.jnatprod.7b01079
Homo sapiens MOLT-16 IC50 6377.51 nM 10.6019/CHEMBL1201861
Homo sapiens MOLT-4 IC50 6736.73 nM 10.6019/CHEMBL1201861
Homo sapiens MONO-MAC-6 IC50 111.36 nM 10.6019/CHEMBL1201861
Homo sapiens MPP-89 IC50 439.45 nM 10.6019/CHEMBL1201861
Homo sapiens MRK-nu-1 IC50 339.6 nM 10.6019/CHEMBL1201861
Homo sapiens MS-1 IC50 4924.48 nM 10.6019/CHEMBL1201861
Homo sapiens MSTO-211H IC50 83920.84 nM 10.6019/CHEMBL1201861
Homo sapiens Multifunctional protein ADE2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Muscle, skeletal receptor tyrosine protein kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Muscle, skeletal receptor tyrosine protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Muscle, skeletal receptor tyrosine protein kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Muscle, skeletal receptor tyrosine protein kinase Residual Activity 13.0 % 10.1042/bj20121418
Homo sapiens Muscle, skeletal receptor tyrosine protein kinase Residual Activity 32.0 % 10.1042/bj20121418
Homo sapiens MV4-11 FC 1000.0 None 10.1021/jm201198w
Homo sapiens MV4-11 GI50 38.0 nM 10.1021/acs.jmedchem.9b01229
Homo sapiens MV4-11 IC50 12.0 nM 10.1182/blood-2009-05-222034
Homo sapiens MV4-11 IC50 19.83 nM 10.6019/CHEMBL1201861
Homo sapiens MV4-11 IC50 40.0 nM 10.1021/acs.jnatprod.9b00468
Homo sapiens Myelin transcription factor 1 Activity 5.0 % 10.1016/j.ejmech.2012.06.007
Homo sapiens Myelin transcription factor 1 IC50 nan None 10.1016/j.ejmech.2012.06.007
Homo sapiens Myosin-14 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Myosin IIIA Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Myosin IIIA Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin IIIA Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myosin-IIIB Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Myosin-IIIB Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin-IIIB Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myosin light chain kinase Kd 2300.0 nM 10.1038/nbt.1990
Homo sapiens Myosin light chain kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens myosin light chain kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens myosin light chain kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens myosin light chain kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myosin light chain kinase family member 4 Kd 640.0 nM 10.1038/nbt1358
Homo sapiens Myosin light chain kinase family member 4 Kd 640.0 nM 10.1038/nbt.1990
Homo sapiens Myosin light chain kinase family member 4 Kd 640.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myosin light chain kinase, smooth muscle Kd 220.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myosin light chain kinase, smooth muscle Kd 2000.0 nM 10.1038/nbt1358
Homo sapiens Myosin light chain kinase, smooth muscle Kd 2000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin light chain kinase, smooth muscle Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myosin light chain kinase, smooth muscle Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Myosin light chain kinase, smooth muscle Residual Activity 10.0 % 10.1042/bj20121418
Homo sapiens Myosin light chain kinase, smooth muscle Residual Activity 13.0 % 10.1042/bj20121418
Homo sapiens Myotonin-protein kinase Kd 3800.0 nM 10.1038/nbt1358
Homo sapiens Myotonin-protein kinase Kd 3800.0 nM 10.1038/nbt.1990
Homo sapiens Myotonin-protein kinase Kd 3800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Myotonin-protein kinase Residual Activity 90.0 % 10.1042/bj20121418
Homo sapiens Myotonin-protein kinase Residual Activity 98.0 % 10.1042/bj20121418
Homo sapiens MZ1-PC IC50 417.83 nM 10.6019/CHEMBL1201861
Homo sapiens MZ2-MEL IC50 5669.02 nM 10.6019/CHEMBL1201861
Homo sapiens MZ7-mel IC50 4156.62 nM 10.6019/CHEMBL1201861
Homo sapiens NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens NALM-6 IC50 108.03 nM 10.6019/CHEMBL1201861
Homo sapiens NB1 IC50 107674.63 nM 10.6019/CHEMBL1201861
Homo sapiens NB10 IC50 18614.58 nM 10.6019/CHEMBL1201861
Homo sapiens NB12 IC50 4837.64 nM 10.6019/CHEMBL1201861
Homo sapiens NB13 IC50 820.57 nM 10.6019/CHEMBL1201861
Homo sapiens NB5 IC50 8643.43 nM 10.6019/CHEMBL1201861
Homo sapiens NB6 IC50 1444.6 nM 10.6019/CHEMBL1201861
Homo sapiens NB69 IC50 734.67 nM 10.6019/CHEMBL1201861
Homo sapiens NCCIT IC50 767.75 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1092 IC50 9792.53 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1155 IC50 140618.84 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1299 IC50 515.72 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1304 IC50 2288.67 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1355 IC50 678.16 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1395 IC50 25941.89 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1417 IC50 35644.01 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1436 IC50 1740.54 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1437 IC50 3559.32 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1522 IC50 1545.0 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1563 IC50 414.84 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1581 IC50 29848.87 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1618 IC50 1955.21 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1623 IC50 26128.17 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1648 IC50 2234.28 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1650 IC50 889.16 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1651 IC50 6707.71 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1693 IC50 1634.92 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1694 IC50 9372.53 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1703 IC50 704.73 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1734 IC50 774.83 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1755 IC50 62.73 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1770 IC50 1313.82 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1792 IC50 330.96 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1793 IC50 800.88 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1838 IC50 15963.6 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H187 IC50 44908.45 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1882 IC50 26457.4 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1963 IC50 4113.51 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H1993 IC50 3536.67 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2009 IC50 486.89 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2030 IC50 230.06 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2052 IC50 698.94 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2081 IC50 23430.79 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2087 IC50 677.82 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H209 IC50 37889.61 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2122 IC50 322.85 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2126 IC50 643.25 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2141 IC50 38032.95 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2170 IC50 443.53 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2171 IC50 28658.73 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2196 IC50 7071.34 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2227 IC50 21384.54 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2228 IC50 2383.84 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H226 IC50 2386.63 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H23 IC50 53686.36 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2342 IC50 108.81 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2347 IC50 2869.73 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2405 IC50 351.15 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H2452 IC50 2805.14 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H28 IC50 265.85 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H292 IC50 773.93 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H322M IC50 84788.51 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H345 IC50 59716.36 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H358 IC50 335.51 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H441 IC50 5072.03 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H446 IC50 14353.45 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H460 IC50 3263.06 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H510A IC50 55441.48 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H520 IC50 12289.64 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H522 IC50 423.0 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H524 IC50 77485.05 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H526 IC50 719.25 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H596 IC50 39180.1 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H630 IC50 1288.05 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H64 IC50 3003.72 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H650 IC50 117.08 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H661 IC50 2023.61 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H69 IC50 1395.49 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H716 IC50 1154.87 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H719 IC50 706.76 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H720 IC50 113826.23 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H727 IC50 11139.18 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H747 IC50 1777.06 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H748 IC50 8067.78 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H810 IC50 210.27 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H82 IC50 85124.17 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H838 IC50 1638.95 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-H889 IC50 74477.94 nM 10.6019/CHEMBL1201861
Homo sapiens NCI-N87 IC50 5326.99 nM 10.6019/CHEMBL1201861
Homo sapiens NEC8 IC50 2156.01 nM 10.6019/CHEMBL1201861
Homo sapiens Nerve growth factor receptor Trk-A Kd 380.0 nM 10.1038/nbt1358
Homo sapiens Nerve growth factor receptor Trk-A Kd 380.0 nM 10.1038/nbt.1990
Homo sapiens Nerve growth factor receptor Trk-A Kd 380.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Nerve growth factor receptor Trk-A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Nerve growth factor receptor Trk-A Residual Activity -1.0 % 10.1042/bj20121418
Homo sapiens Nerve growth factor receptor Trk-A Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens Neurotrophic tyrosine kinase receptor type 2 Kd 310.0 nM 10.1038/nbt1358
Homo sapiens Neurotrophic tyrosine kinase receptor type 2 Kd 310.0 nM 10.1038/nbt.1990
Homo sapiens Neurotrophic tyrosine kinase receptor type 2 Kd 310.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Neurotrophic tyrosine kinase receptor type 2 Residual Activity -12.0 % 10.1042/bj20121418
Homo sapiens Neurotrophic tyrosine kinase receptor type 2 Residual Activity 23.0 % 10.1042/bj20121418
Homo sapiens NH-12 IC50 1402.62 nM 10.6019/CHEMBL1201861
Homo sapiens NKM-1 IC50 39.42 nM 10.6019/CHEMBL1201861
Homo sapiens NMC-G1 IC50 223.59 nM 10.6019/CHEMBL1201861
Homo sapiens no-10 IC50 9306.33 nM 10.6019/CHEMBL1201861
Homo sapiens no-11 IC50 3232.09 nM 10.6019/CHEMBL1201861
Homo sapiens NOMO-1 IC50 23532.75 nM 10.6019/CHEMBL1201861
Homo sapiens Non-receptor tyrosine-protein kinase TNK1 Kd 83.0 nM 10.1038/nbt1358
Homo sapiens Non-receptor tyrosine-protein kinase TNK1 Kd 83.0 nM 10.1038/nbt.1990
Homo sapiens Non-receptor tyrosine-protein kinase TNK1 Kd 83.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Non-receptor tyrosine-protein kinase TNK1 Kd 863.0 nM 10.1126/science.aan4368
Homo sapiens NOS-1 IC50 3098.72 nM 10.6019/CHEMBL1201861
Homo sapiens NT-3 growth factor receptor Kd 1700.0 nM 10.1038/nbt1358
Homo sapiens NT-3 growth factor receptor Kd 1700.0 nM 10.1038/nbt.1990
Homo sapiens NT-3 growth factor receptor Kd 1700.0 nM 10.1182/blood-2009-05-222034
Homo sapiens NTERA-2-cl-D1 IC50 208.95 nM 10.6019/CHEMBL1201861
Homo sapiens NUAK family SNF1-like kinase 1 Kd 41.0 nM 10.1038/nbt1358
Homo sapiens NUAK family SNF1-like kinase 1 Kd 41.0 nM 10.1038/nbt.1990
Homo sapiens NUAK family SNF1-like kinase 1 Kd 41.0 nM 10.1182/blood-2009-05-222034
Homo sapiens NUAK family SNF1-like kinase 1 Residual Activity 7.0 % 10.1042/bj20121418
Homo sapiens NUAK family SNF1-like kinase 2 Kd 63.0 nM 10.1038/nbt1358
Homo sapiens NUAK family SNF1-like kinase 2 Kd 63.0 nM 10.1038/nbt.1990
Homo sapiens NUAK family SNF1-like kinase 2 Kd 63.0 nM 10.1182/blood-2009-05-222034
Homo sapiens NUAK family SNF1-like kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens NUGC-3 IC50 1569.28 nM 10.6019/CHEMBL1201861
Homo sapiens NY IC50 137.48 nM 10.6019/CHEMBL1201861
Homo sapiens OAW-28 IC50 1056.9 nM 10.6019/CHEMBL1201861
Homo sapiens OAW-42 IC50 580.91 nM 10.6019/CHEMBL1201861
Homo sapiens Obg-like ATPase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens OCI-AML2 GI50 6244000.0 nM 10.1021/acs.jmedchem.8b01594
Homo sapiens OCI-AML2 IC50 2074.76 nM 10.6019/CHEMBL1201861
Homo sapiens OCUB-M IC50 1359.15 nM 10.6019/CHEMBL1201861
Homo sapiens OE19 IC50 5517.21 nM 10.6019/CHEMBL1201861
Homo sapiens OE33 IC50 4986.09 nM 10.6019/CHEMBL1201861
Homo sapiens OMC-1 IC50 30064.65 nM 10.6019/CHEMBL1201861
Homo sapiens ONS-76 IC50 278.41 nM 10.6019/CHEMBL1201861
Homo sapiens OPM-2 IC50 1658.01 nM 10.6019/CHEMBL1201861
Homo sapiens OS-RC-2 IC50 335.12 nM 10.6019/CHEMBL1201861
Homo sapiens OVCAR-3 IC50 1226.96 nM 10.6019/CHEMBL1201861
Homo sapiens OVCAR-4 IC50 1847.7 nM 10.6019/CHEMBL1201861
Homo sapiens OVCAR-5 IC50 691.67 nM 10.6019/CHEMBL1201861
Homo sapiens OVCAR-8 IC50 2031.5 nM 10.6019/CHEMBL1201861
Homo sapiens P12-Ichikawa IC50 11109.55 nM 10.6019/CHEMBL1201861
Homo sapiens P30-OHK IC50 612.46 nM 10.6019/CHEMBL1201861
Homo sapiens P31-FUJ IC50 125376.1 nM 10.6019/CHEMBL1201861
Homo sapiens PA-1 IC50 184.99 nM 10.6019/CHEMBL1201861
Homo sapiens PANC-03-27 IC50 160.2 nM 10.6019/CHEMBL1201861
Homo sapiens PANC-08-13 IC50 4804.63 nM 10.6019/CHEMBL1201861
Homo sapiens Panc1005 IC50 356.33 nM 10.6019/CHEMBL1201861
Homo sapiens PAS domain-containing serine/threonine-protein kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens PAS domain-containing serine/threonine-protein kinase Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens PAS domain-containing serine/threonine-protein kinase Residual Activity 85.0 % 10.1042/bj20121418
Homo sapiens PBMC IC50 10000.0 nM 10.1021/acs.jnatprod.9b00468
Homo sapiens PC-14 IC50 538.55 nM 10.6019/CHEMBL1201861
Homo sapiens PC-3 IC50 4665.09 nM 10.6019/CHEMBL1201861
Homo sapiens Peripheral plasma membrane protein CASK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Peroxisomal acyl-coenzyme A oxidase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens PF-382 IC50 387.56 nM 10.6019/CHEMBL1201861
Homo sapiens PFSK-1 IC50 14106.7 nM 10.6019/CHEMBL1201861
Homo sapiens Phenylalanine--tRNA ligase beta subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphatidylethanolamine-binding protein 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide Kd 1400.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma Kd 570.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma Kd 570.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha Kd 310.0 nM 10.1038/nbt1358
Homo sapiens Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha Kd 310.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha Kd 310.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 beta Kd 270.0 nM 10.1038/nbt1358
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 beta Kd 270.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 beta Kd 270.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphofructokinase platelet type Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphorylase kinase gamma subunit 1 Kd 190.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphorylase kinase gamma subunit 1 Kd 900.0 nM 10.1038/nbt1358
Homo sapiens Phosphorylase kinase gamma subunit 1 Kd 900.0 nM 10.1038/nbt.1990
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd 900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd 1400.0 nM 10.1038/nbt1358
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd 1400.0 nM 10.1038/nbt.1990
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphorylase kinase gamma subunit 2 Residual Activity 29.0 % 10.1042/bj20121418
Homo sapiens Phosphorylase kinase gamma subunit 2 Residual Activity 44.0 % 10.1042/bj20121418
Homo sapiens PI3-kinase p110-alpha subunit Kd 1100.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-alpha subunit Kd 1100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PI3-kinase p110-alpha subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens PI3-kinase p110-alpha subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-alpha subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PI3-kinase p110-beta subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-beta subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PI3-kinase p110-delta subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-delta subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PI3-kinase p110-gamma subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-gamma subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PI4-kinase beta subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI4-kinase beta subunit Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Platelet-derived growth factor receptor alpha Kd 180.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Platelet-derived growth factor receptor alpha Kd 380.0 nM 10.1038/nbt1358
Homo sapiens Platelet-derived growth factor receptor alpha Kd 380.0 nM 10.1038/nbt.1990
Homo sapiens Platelet-derived growth factor receptor alpha Residual Activity 32.0 % 10.1042/bj20121418
Homo sapiens Platelet-derived growth factor receptor alpha Residual Activity 54.0 % 10.1042/bj20121418
Homo sapiens Platelet-derived growth factor receptor beta Kd 110.0 nM 10.1038/nbt1358
Homo sapiens Platelet-derived growth factor receptor beta Kd 110.0 nM 10.1038/nbt.1990
Homo sapiens Platelet-derived growth factor receptor beta Kd 380.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Platelet-derived growth factor receptor beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Platelet-derived growth factor receptor beta Residual Activity 25.0 % 10.1042/bj20121418
Homo sapiens Platelet-derived growth factor receptor beta Residual Activity 46.0 % 10.1042/bj20121418
Homo sapiens PLC-PRF-5 IC50 44411.04 nM 10.6019/CHEMBL1201861
Homo sapiens Probable ATP-dependent RNA helicase DDX6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein delta homolog 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C alpha Kd 720.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C alpha Residual Activity 14.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C alpha Residual Activity 36.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C beta Residual Activity 14.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C beta Residual Activity 45.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C beta Residual Activity 61.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C beta Residual Activity 66.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C delta Kd 320.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C delta Kd 320.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C delta Kd 320.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C delta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C delta Residual Activity 9.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C delta Residual Activity 21.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C epsilon Kd 540.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C epsilon Kd 540.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C epsilon Kd 540.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C epsilon Residual Activity 14.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C epsilon Residual Activity 42.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C eta Kd 290.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C eta Kd 290.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C eta Kd 290.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C eta Residual Activity 29.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C eta Residual Activity 84.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C gamma Residual Activity 6.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C gamma Residual Activity 15.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C iota Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C iota Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C iota Residual Activity 79.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C iota Residual Activity 85.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C mu Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C mu Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C mu Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C mu Residual Activity 79.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C mu Residual Activity 85.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C nu Kd 3200.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C nu Kd 3200.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C nu Kd 3200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C nu Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C theta Kd 920.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C theta Kd 920.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C theta Kd 920.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase C theta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C theta Residual Activity 11.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C theta Residual Activity 15.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C zeta Residual Activity 101.0 % 10.1042/bj20121418
Homo sapiens Protein kinase C zeta Residual Activity 102.0 % 10.1042/bj20121418
Homo sapiens Protein kinase N1 Kd 9.3 nM 10.1038/nbt1358
Homo sapiens Protein kinase N1 Kd 9.3 nM 10.1038/nbt.1990
Homo sapiens Protein kinase N1 Kd 9.3 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase N1 Kd 189.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase N2 Kd 15.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase N2 Kd 15.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase N2 Kd 15.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein kinase N2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase N2 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Protein kinase N2 Residual Activity 2.0 % 10.1042/bj20121418
Homo sapiens Protein tyrosine kinase 2 beta Kd 660.0 nM 10.1038/nbt1358
Homo sapiens Protein tyrosine kinase 2 beta Kd 660.0 nM 10.1038/nbt.1990
Homo sapiens Protein tyrosine kinase 2 beta Kd 660.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Protein tyrosine kinase 2 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein tyrosine kinase 2 beta Residual Activity 10.0 % 10.1042/bj20121418
Homo sapiens Protein tyrosine kinase 2 beta Residual Activity 16.0 % 10.1042/bj20121418
Homo sapiens Proto-oncogene tyrosine-protein kinase MER Kd 2900.0 nM 10.1038/nbt1358
Homo sapiens Proto-oncogene tyrosine-protein kinase MER Kd 2900.0 nM 10.1038/nbt.1990
Homo sapiens Proto-oncogene tyrosine-protein kinase MER Kd 2900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Proto-oncogene tyrosine-protein kinase MER Residual Activity 6.0 % 10.1042/bj20121418
Homo sapiens Proto-oncogene tyrosine-protein kinase MER Residual Activity 8.0 % 10.1042/bj20121418
Homo sapiens Proto-oncogene tyrosine-protein kinase ROS Kd 430.0 nM 10.1038/nbt1358
Homo sapiens Proto-oncogene tyrosine-protein kinase ROS Kd 430.0 nM 10.1038/nbt.1990
Homo sapiens Proto-oncogene tyrosine-protein kinase ROS Kd 430.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Proto-oncogene tyrosine-protein kinase ROS Residual Activity 50.0 % 10.1042/bj20121418
Homo sapiens Proto-oncogene tyrosine-protein kinase ROS Residual Activity 63.0 % 10.1042/bj20121418
Homo sapiens PSN1 IC50 51755.46 nM 10.6019/CHEMBL1201861
Homo sapiens Putative heat shock protein HSP 90-beta 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Putative uncharacterized serine/threonine-protein kinase SgK110 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Putative uncharacterized serine/threonine-protein kinase SgK110 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Pyridoxal kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens QIMR-WIL IC50 1653.64 nM 10.6019/CHEMBL1201861
Homo sapiens Quinone reductase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Rab-like protein 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Raji IC50 54813.14 nM 10.6019/CHEMBL1201861
Homo sapiens Ramos-2G6-4C10 IC50 2943.87 nM 10.6019/CHEMBL1201861
Homo sapiens Ras-related protein Rab-10 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ras-related protein Rab-6A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens RCC10RGB IC50 1858.68 nM 10.6019/CHEMBL1201861
Homo sapiens RCM-1 IC50 2292.98 nM 10.6019/CHEMBL1201861
Homo sapiens RD IC50 1072.08 nM 10.6019/CHEMBL1201861
Homo sapiens Receptor-interacting serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Receptor-interacting serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Receptor-interacting serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Receptor-interacting serine/threonine-protein kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Receptor-interacting serine/threonine-protein kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Receptor-interacting serine/threonine-protein kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Receptor protein-tyrosine kinase erbB-4 Kd 3100.0 nM 10.1038/nbt.1990
Homo sapiens Receptor protein-tyrosine kinase erbB-4 Kd 3100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Receptor protein-tyrosine kinase erbB-4 Residual Activity 51.0 % 10.1042/bj20121418
Homo sapiens Receptor protein-tyrosine kinase erbB-4 Residual Activity 67.0 % 10.1042/bj20121418
Homo sapiens Receptor tyrosine-protein kinase erbB-3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Receptor tyrosine-protein kinase erbB-3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens REH IC50 513.34 nM 10.6019/CHEMBL1201861
Homo sapiens RERF-LC-MS IC50 3983.53 nM 10.6019/CHEMBL1201861
Homo sapiens RH-1 IC50 56437.62 nM 10.6019/CHEMBL1201861
Homo sapiens Rho-associated protein kinase 1 Kd 7800.0 nM 10.1038/nbt.1990
Homo sapiens Rho-associated protein kinase 1 Kd 7800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Rho-associated protein kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Rho-associated protein kinase 1 Residual Activity 110.0 % 10.1042/bj20121418
Homo sapiens Rho-associated protein kinase 1 Residual Activity 115.0 % 10.1042/bj20121418
Homo sapiens Rho-associated protein kinase 2 Kd 2300.0 nM 10.1038/nbt.1990
Homo sapiens Rho-associated protein kinase 2 Kd 2300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Rho-associated protein kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Rho-associated protein kinase 2 Residual Activity 57.0 % 10.1042/bj20121418
Homo sapiens Rho-associated protein kinase 2 Residual Activity 79.0 % 10.1042/bj20121418
Homo sapiens Rhodopsin kinase Kd 85.0 nM 10.1038/nbt.1990
Homo sapiens Rhodopsin kinase Kd 85.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase 1 Kd 1300.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase 1 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase 1 Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 260.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 690.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 690.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 740.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 1 Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 1 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd 240.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd 730.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd 730.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 2 Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 2 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd 740.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd 740.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd 3497.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 3 Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 3 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 260.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 260.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 690.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 4 Residual Activity 8.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 4 Residual Activity 12.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 240.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 240.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 730.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 5 Residual Activity 8.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 5 Residual Activity 13.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 419.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 1500.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 1500.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 1500.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Ribosomal protein S6 kinase alpha 6 Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens Ribosomal protein S6 kinase alpha 6 Residual Activity 3.0 % 10.1042/bj20121418
Homo sapiens RKO IC50 420.17 nM 10.6019/CHEMBL1201861
Homo sapiens RL IC50 110401.09 nM 10.6019/CHEMBL1201861
Homo sapiens RL95-2 IC50 795.72 nM 10.6019/CHEMBL1201861
Homo sapiens RMG-I IC50 2864.07 nM 10.6019/CHEMBL1201861
Homo sapiens RNA cytidine acetyltransferase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens RO82-W-1 IC50 1544.06 nM 10.6019/CHEMBL1201861
Homo sapiens RPMI-2650 IC50 2786.33 nM 10.6019/CHEMBL1201861
Homo sapiens RPMI-6666 IC50 3411.59 nM 10.6019/CHEMBL1201861
Homo sapiens RPMI-7951 IC50 611.23 nM 10.6019/CHEMBL1201861
Homo sapiens RPMI-8226 IC50 20378.74 nM 10.6019/CHEMBL1201861
Homo sapiens RPMI 8402 IC50 577.66 nM 10.6019/CHEMBL1201861
Homo sapiens RPMI-8866 IC50 109035.88 nM 10.6019/CHEMBL1201861
Homo sapiens RS4-11 GI50 400.0 nM 10.1021/acs.jmedchem.9b01229
Homo sapiens RS4-11 IC50 624.17 nM 10.6019/CHEMBL1201861
Homo sapiens RT-112 IC50 974.83 nM 10.6019/CHEMBL1201861
Homo sapiens RT-4 IC50 4617.34 nM 10.6019/CHEMBL1201861
Homo sapiens RVH-421 IC50 24894.83 nM 10.6019/CHEMBL1201861
Homo sapiens RXF 393 IC50 406.04 nM 10.6019/CHEMBL1201861
Homo sapiens S-117 IC50 24111.38 nM 10.6019/CHEMBL1201861
Homo sapiens S-adenosylmethionine synthase isoform type-2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens SAOS-2 IC50 3742.8 nM 10.6019/CHEMBL1201861
Homo sapiens SAS IC50 54879.18 nM 10.6019/CHEMBL1201861
Homo sapiens SBC-1 IC50 53824.14 nM 10.6019/CHEMBL1201861
Homo sapiens SBC-5 IC50 1273.89 nM 10.6019/CHEMBL1201861
Homo sapiens SCC-15 IC50 574.07 nM 10.6019/CHEMBL1201861
Homo sapiens SCC-25 IC50 1048.87 nM 10.6019/CHEMBL1201861
Homo sapiens SCC-3 IC50 128769.76 nM 10.6019/CHEMBL1201861
Homo sapiens SCC-4 IC50 239.67 nM 10.6019/CHEMBL1201861
Homo sapiens SCC-9 IC50 872.86 nM 10.6019/CHEMBL1201861
Homo sapiens SCH IC50 115065.09 nM 10.6019/CHEMBL1201861
Homo sapiens SCLC-21H IC50 151728.39 nM 10.6019/CHEMBL1201861
Homo sapiens Septin-9 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 10 Kd 590.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 10 Kd 590.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 10 Kd 590.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 10 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 10 Residual Activity 9.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase 10 Residual Activity 21.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase 11 Kd 350.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 11 Kd 350.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 11 Kd 350.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 11 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 11 Residual Activity 93.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase 11 Residual Activity 95.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase 16 Kd 280.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 16 Kd 280.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 16 Kd 280.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 16 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 17A Kd 1900.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 17A Kd 1900.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 17A Kd 1900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 17A Residual Activity 9.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase 17A Residual Activity 16.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase 17B Kd 4700.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 17B Kd 4700.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 17B Kd 4700.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 2 Kd 220.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 2 Kd 220.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 2 Kd 220.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 24 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 24 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 24 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 24 Residual Activity 7.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase 24 Residual Activity 17.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase 25 Kd 1800.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 25 Kd 1800.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 25 Kd 1800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 32A Kd 2400.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 32B Inhibition nan % 10.1021/jm201265f
Homo sapiens Serine/threonine-protein kinase 32B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 32B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 32B Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 32C Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 32C Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 32C Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 33 Kd 190.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 33 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 33 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 33 Residual Activity 13.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase 33 Residual Activity 25.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase 35 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 35 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 36 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 36 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 36 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 38 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 38 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase 38-like Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 38-like Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 38-like Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase AKT Kd 950.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase AKT Kd 950.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase AKT Kd 950.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase AKT Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase AKT Residual Activity 97.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase AKT Residual Activity 99.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase AKT2 Kd 780.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase AKT2 Kd 780.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase AKT2 Kd 780.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase AKT2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase AKT2 Residual Activity 46.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase AKT2 Residual Activity 80.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase AKT3 Kd 4400.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase AKT3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase AKT3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase AKT3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase AKT3 Residual Activity 14.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase AKT3 Residual Activity 22.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase A-Raf Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Aurora-A IC50 80.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 19.29 nM 10.6019/CHEMBL3885741
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 120.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 120.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 120.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 477.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Aurora-A k_off 0.004557 s-1 10.6019/CHEMBL3885741
Homo sapiens Serine/threonine-protein kinase Aurora-A kon 238000.0 Ms-1 10.6019/CHEMBL3885741
Homo sapiens Serine/threonine-protein kinase Aurora-A Residual Activity -3.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Aurora-A Residual Activity -2.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Aurora-B Kd 62.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Aurora-B Kd 62.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Aurora-B Kd 62.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Aurora-B Kd 2409.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Aurora-B Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Aurora-B Residual Activity 3.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Aurora-C Kd 170.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Aurora-C Kd 170.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Aurora-C Kd 170.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Aurora-C Residual Activity 20.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Aurora-C Residual Activity 62.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase B-raf Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase B-raf Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase B-raf Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase B-raf Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Chk1 Kd 1300.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Chk1 Kd 1300.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Chk1 Kd 1300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Chk1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Chk1 Residual Activity 59.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Chk1 Residual Activity 65.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Chk2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Chk2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Chk2 Residual Activity 54.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Chk2 Residual Activity 79.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase c-TAK1 Kd 21.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase c-TAK1 Kd 21.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase c-TAK1 Kd 21.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase c-TAK1 Kd 1090.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase D2 Kd 6300.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase D2 Kd 6300.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase D2 Kd 6300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase D2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase D2 Residual Activity 92.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase D2 Residual Activity 101.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase DCLK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase DCLK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase DCLK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase DCLK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase DCLK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase DCLK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase DCLK2 Residual Activity 38.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase DCLK2 Residual Activity 75.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase DCLK3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase DCLK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase DCLK3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase EEF2K Residual Activity 83.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase EEF2K Residual Activity 98.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1 Kd 2300.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1 Kd 2300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase GAK Kd 380.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase GAK Kd 380.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase GAK Kd 380.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase GAK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase haspin Residual Activity 43.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase haspin Residual Activity 78.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase ICK Kd 5900.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ICK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase ILK-1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase LATS1 Kd 1100.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase LATS1 Kd 1100.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase LATS1 Kd 1100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase LATS1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase LATS2 Kd 2200.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase LATS2 Kd 2200.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase LATS2 Kd 2200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MAK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MAK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MARK1 Kd 170.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MARK1 Kd 170.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MARK1 Kd 170.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MARK1 Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase MARK1 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase MRCK-A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MRCK-A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MRCK-A Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MRCK-A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MRCK-A Residual Activity 93.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase MRCK-A Residual Activity 102.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase MRCK beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MRCK beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MRCK beta Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MRCK beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MRCK beta Residual Activity 68.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase MRCK beta Residual Activity 85.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase MRCK gamma Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MRCK gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MRCK gamma Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MST1 Kd 17.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MST1 Kd 40.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MST1 Kd 40.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MST1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MST1 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase MST1 Residual Activity 2.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase MST2 Kd 40.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MST2 Kd 220.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MST2 Kd 220.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MST2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MST2 Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase MST2 Residual Activity 3.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase MST4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MST4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MST4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase MST4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase mTOR Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase mTOR Residual Activity 83.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase mTOR Residual Activity 95.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase mTOR Residual Activity 103.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase mTOR Residual Activity 107.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Nek1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Nek1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase Nek1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Nek11 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek11 Residual Activity 47.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Nek11 Residual Activity 49.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase NEK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase NEK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase NEK2 Residual Activity 82.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase NEK2 Residual Activity 86.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Nek3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Nek3 Residual Activity 37.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Nek3 Residual Activity 102.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Nek4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Nek5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek5 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase NEK6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase NEK6 Residual Activity 92.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase NEK6 Residual Activity 93.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase NEK7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK7 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase NEK7 Residual Activity 82.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase NEK7 Residual Activity 91.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase NEK9 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK9 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK9 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase NEK9 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase NIM1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NIM1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine protein kinase NLK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine protein kinase NLK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine protein kinase NLK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine protein kinase NLK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine protein kinase NLK Residual Activity 73.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine protein kinase NLK Residual Activity 90.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase OSR1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase OSR1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK 1 Kd 2000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK 1 Kd 2100.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 1 Kd 2100.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 2 Kd 2100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK 2 Kd 3300.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 2 Kd 3300.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PAK 2 Residual Activity 50.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PAK 2 Residual Activity 72.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PAK 3 Kd 180.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 3 Kd 180.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 3 Kd 3300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK 3 Residual Activity 33.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PAK 3 Residual Activity 107.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PAK 4 Residual Activity 43.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PAK 4 Residual Activity 64.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PAK6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK6 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK6 Residual Activity 26.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PAK6 Residual Activity 49.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PAK7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK7 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PAK7 Residual Activity 48.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PAK7 Residual Activity 52.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PCTAIRE-2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PCTAIRE-2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PCTAIRE-2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PCTAIRE-3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PCTAIRE-3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PCTAIRE-3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PFTAIRE-1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PFTAIRE-1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PFTAIRE-1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PFTAIRE-2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PFTAIRE-2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PIM1 Kd 560.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PIM1 Kd 560.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PIM1 Kd 560.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PIM1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PIM1 Residual Activity 16.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PIM1 Residual Activity 33.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PIM2 Kd 3100.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PIM2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PIM2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PIM2 Residual Activity 80.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PIM2 Residual Activity 94.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PIM3 Kd 560.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PIM3 Kd 560.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PIM3 Kd 560.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PIM3 Residual Activity 88.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PIM3 Residual Activity 93.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PLK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PLK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PLK1 Residual Activity 61.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PLK1 Residual Activity 87.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PLK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PLK2 Residual Activity 86.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PLK2 Residual Activity 100.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PLK3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PLK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PLK3 Residual Activity 92.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PLK3 Residual Activity 95.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 66.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 66.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 66.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 213.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PRKX Kd 960.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PRKX Kd 960.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PRKX Kd 960.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase PRKX Residual Activity 12.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PRKX Residual Activity 24.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase PRP4 homolog Kd 55.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PRP4 homolog Kd 55.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RAF Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RAF Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RAF Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RAF Residual Activity 80.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase RAF Residual Activity 90.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase receptor R3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase receptor R3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase receptor R3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RIO1 Kd 1200.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RIO1 Kd 1200.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIO1 Kd 1200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RIO2 Kd 97.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIO2 Kd 97.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RIO3 Kd 398.11 nM None
Homo sapiens Serine/threonine-protein kinase RIO3 Kd 420.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RIO3 Kd 420.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIO3 Kd 420.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RIO3 Kd 420.0 nM None
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase RIPK2 Residual Activity 70.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase RIPK2 Residual Activity 88.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase SBK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Sgk1 Residual Activity 18.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Sgk1 Residual Activity 57.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Sgk2 Residual Activity 46.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Sgk2 Residual Activity 80.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Sgk3 Kd 1400.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Sgk3 Residual Activity 78.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase Sgk3 Residual Activity 87.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase SIK1 Kd 160.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SIK1 Kd 160.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SIK1 Kd 160.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase SIK1 Residual Activity 2.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase SIK1 Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase SIK2 Kd 560.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SIK2 Kd 560.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SIK2 Kd 560.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase SIK2 Kd 1149.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase SIK3 Kd 98.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SIK3 Kd 98.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase SIK3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase SRPK1 Kd 42.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SRPK1 Kd 42.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SRPK1 Kd 42.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase SRPK1 Residual Activity 55.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase SRPK1 Residual Activity 78.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase SRPK2 Kd 330.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SRPK2 Kd 330.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SRPK2 Kd 330.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase SRPK2 Residual Activity 48.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase SRPK2 Residual Activity 64.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase SRPK3 Kd 80.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SRPK3 Kd 80.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase SRPK3 Residual Activity 77.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase SRPK3 Residual Activity 96.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase TAO1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TAO1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase TAO1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TAO1 Residual Activity 17.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase TAO1 Residual Activity 50.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase TAO2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TAO2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TAO2 Residual Activity 47.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase TAO2 Residual Activity 83.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase TAO3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TAO3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase TAO3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TAO3 Residual Activity 29.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase TAO3 Residual Activity 42.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase TBK1 Kd 9.3 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TBK1 Kd 9.3 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase TBK1 Kd 188.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TBK1 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase TBK1 Residual Activity 2.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase TNNI3K Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase TNNI3K Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TNNI3K Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase tousled-like 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase tousled-like 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase tousled-like 1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase tousled-like 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase tousled-like 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase tousled-like 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase tousled-like 2 Residual Activity 72.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase tousled-like 2 Residual Activity 95.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase ULK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ULK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase ULK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase ULK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ULK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase ULK2 Residual Activity 76.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase ULK2 Residual Activity 96.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase ULK3 Kd 1300.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ULK3 Kd 1300.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase ULK3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase ULK3 Residual Activity 5.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase ULK3 Residual Activity 17.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase VRK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase VRK2 Residual Activity 94.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase VRK2 Residual Activity 99.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase WEE1 Kd 4600.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase WEE1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase WEE1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Serine/threonine-protein kinase WEE1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase WNK2 Residual Activity 60.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase WNK2 Residual Activity 90.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase WNK3 Residual Activity 76.0 % 10.1042/bj20121418
Homo sapiens Serine/threonine-protein kinase WNK3 Residual Activity 91.0 % 10.1042/bj20121418
Homo sapiens Serum PPB nan % 10.1021/acsmedchemlett.5b00498
Homo sapiens SF-126 IC50 247.31 nM 10.6019/CHEMBL1201861
Homo sapiens SF-268 IC50 393.81 nM 10.6019/CHEMBL1201861
Homo sapiens SF-295 IC50 272.57 nM 10.6019/CHEMBL1201861
Homo sapiens SF-539 IC50 27924.79 nM 10.6019/CHEMBL1201861
Homo sapiens SH-4 IC50 492.71 nM 10.6019/CHEMBL1201861
Homo sapiens SHP77 IC50 6872.31 nM 10.6019/CHEMBL1201861
Homo sapiens SIG-M5 IC50 482.99 nM 10.6019/CHEMBL1201861
Homo sapiens SiHa IC50 13104.46 nM 10.6019/CHEMBL1201861
Homo sapiens SIMA IC50 2708.6 nM 10.6019/CHEMBL1201861
Homo sapiens SJRH30 IC50 1788.8 nM 10.6019/CHEMBL1201861
Homo sapiens SJSA-1 IC50 8403.63 nM 10.6019/CHEMBL1201861
Homo sapiens SK-CO-1 IC50 518.49 nM 10.6019/CHEMBL1201861
Homo sapiens SKG-IIIa IC50 3765.72 nM 10.6019/CHEMBL1201861
Homo sapiens SK-HEP1 IC50 512.97 nM 10.6019/CHEMBL1201861
Homo sapiens SK-LMS-1 IC50 353.35 nM 10.6019/CHEMBL1201861
Homo sapiens SK-LU-1 IC50 439.85 nM 10.6019/CHEMBL1201861
Homo sapiens SK-MEL-1 IC50 22693.28 nM 10.6019/CHEMBL1201861
Homo sapiens SK-MEL-2 IC50 2970.03 nM 10.6019/CHEMBL1201861
Homo sapiens SK-MEL-24 IC50 41487.33 nM 10.6019/CHEMBL1201861
Homo sapiens SK-MEL-28 IC50 34809.98 nM 10.6019/CHEMBL1201861
Homo sapiens SK-MEL3 IC50 1263.72 nM 10.6019/CHEMBL1201861
Homo sapiens SK-MEL-30 IC50 399.13 nM 10.6019/CHEMBL1201861
Homo sapiens SK-MES-1 IC50 314.85 nM 10.6019/CHEMBL1201861
Homo sapiens SK-MM-2 IC50 2176.22 nM 10.6019/CHEMBL1201861
Homo sapiens SK-N-AS IC50 35399.65 nM 10.6019/CHEMBL1201861
Homo sapiens SK-N-DZ IC50 36200.47 nM 10.6019/CHEMBL1201861
Homo sapiens SK-NEP-1 IC50 15238.18 nM 10.6019/CHEMBL1201861
Homo sapiens SK-N-FI IC50 109732.76 nM 10.6019/CHEMBL1201861
Homo sapiens SK-OV-3 IC50 5718.1 nM 10.6019/CHEMBL1201861
Homo sapiens SK-PN-DW IC50 2460.29 nM 10.6019/CHEMBL1201861
Homo sapiens SK-UT-1 IC50 329.52 nM 10.6019/CHEMBL1201861
Homo sapiens SN12C IC50 2627.5 nM 10.6019/CHEMBL1201861
Homo sapiens SNB-75 IC50 773.11 nM 10.6019/CHEMBL1201861
Homo sapiens SNF-related serine/threonine-protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens SNG-M IC50 492.83 nM 10.6019/CHEMBL1201861
Homo sapiens SNU1 IC50 2703.25 nM 10.6019/CHEMBL1201861
Homo sapiens SNU-16 IC50 150284.93 nM 10.6019/CHEMBL1201861
Homo sapiens SNU-387 IC50 138.72 nM 10.6019/CHEMBL1201861
Homo sapiens SNU-423 IC50 236.57 nM 10.6019/CHEMBL1201861
Homo sapiens SNU-449 IC50 131.7 nM 10.6019/CHEMBL1201861
Homo sapiens SNU-475 IC50 7249.92 nM 10.6019/CHEMBL1201861
Homo sapiens SNU-5 IC50 10324.22 nM 10.6019/CHEMBL1201861
Homo sapiens SNU-C1 IC50 5168.75 nM 10.6019/CHEMBL1201861
Homo sapiens SNU-C2B IC50 60951.53 nM 10.6019/CHEMBL1201861
Homo sapiens SPS1/STE20-related protein kinase YSK4 Kd 15.0 nM 10.1038/nbt.1990
Homo sapiens SPS1/STE20-related protein kinase YSK4 Kd 15.0 nM 10.1182/blood-2009-05-222034
Homo sapiens SR IC50 365.71 nM 10.6019/CHEMBL1201861
Homo sapiens ST486 IC50 349.39 nM 10.6019/CHEMBL1201861
Homo sapiens STE20-related kinase adapter protein alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens STE20/SPS1-related proline-alanine-rich protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens STE20/SPS1-related proline-alanine-rich protein kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor IC50 109.0 nM 10.1021/acs.jmedchem.9b01229
Homo sapiens Stem cell growth factor receptor Kd 7.7 nM 10.1016/j.ejmech.2011.02.057
Homo sapiens Stem cell growth factor receptor Kd 7.7 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 7.7 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 7.7 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Kd 16.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 41.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 41.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Kd 43.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 150.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 150.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 150.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Kd 200.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 200.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Kd 220.0 nM 10.1016/j.ejmech.2011.02.057
Homo sapiens Stem cell growth factor receptor Kd 220.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 220.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 220.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Kd 1600.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 1600.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 1600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Stem cell growth factor receptor Residual Activity 39.0 % 10.1042/bj20121418
Homo sapiens Stem cell growth factor receptor Residual Activity 65.0 % 10.1042/bj20121418
Homo sapiens Structural maintenance of chromosomes protein 1A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Structural maintenance of chromosomes protein 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens SU-DHL-1 IC50 3069.59 nM 10.6019/CHEMBL1201861
Homo sapiens SUP-T1 IC50 654.24 nM 10.6019/CHEMBL1201861
Homo sapiens SW1088 IC50 337.97 nM 10.6019/CHEMBL1201861
Homo sapiens SW13 IC50 6544.51 nM 10.6019/CHEMBL1201861
Homo sapiens SW1417 IC50 5504.05 nM 10.6019/CHEMBL1201861
Homo sapiens SW1463 IC50 18174.07 nM 10.6019/CHEMBL1201861
Homo sapiens SW1573 IC50 2284.72 nM 10.6019/CHEMBL1201861
Homo sapiens SW1710 IC50 133.16 nM 10.6019/CHEMBL1201861
Homo sapiens SW1783 IC50 733.37 nM 10.6019/CHEMBL1201861
Homo sapiens SW1990 IC50 8472.25 nM 10.6019/CHEMBL1201861
Homo sapiens SW48 IC50 266.8 nM 10.6019/CHEMBL1201861
Homo sapiens SW-620 IC50 1617.01 nM 10.6019/CHEMBL1201861
Homo sapiens SW626 IC50 1168.13 nM 10.6019/CHEMBL1201861
Homo sapiens SW684 IC50 4788.38 nM 10.6019/CHEMBL1201861
Homo sapiens SW756 IC50 29286.6 nM 10.6019/CHEMBL1201861
Homo sapiens SW780 IC50 411.42 nM 10.6019/CHEMBL1201861
Homo sapiens SW837 IC50 70153.73 nM 10.6019/CHEMBL1201861
Homo sapiens SW872 IC50 944.59 nM 10.6019/CHEMBL1201861
Homo sapiens SW948 IC50 21458.18 nM 10.6019/CHEMBL1201861
Homo sapiens SW 954 IC50 1259.11 nM 10.6019/CHEMBL1201861
Homo sapiens SW 962 IC50 4364.27 nM 10.6019/CHEMBL1201861
Homo sapiens SW982 IC50 45.58 nM 10.6019/CHEMBL1201861
Homo sapiens T-24 IC50 1918.93 nM 10.6019/CHEMBL1201861
Homo sapiens T47D IC50 5248.03 nM 10.6019/CHEMBL1201861
Homo sapiens T84 IC50 16449.66 nM 10.6019/CHEMBL1201861
Homo sapiens T98G IC50 189.95 nM 10.6019/CHEMBL1201861
Homo sapiens TALL-1 IC50 123127.45 nM 10.6019/CHEMBL1201861
Homo sapiens Tankyrase-2 Kd 120.0 nM 10.1182/blood-2009-05-222034
Homo sapiens TCC-SUP IC50 164.69 nM 10.6019/CHEMBL1201861
Homo sapiens TE-1 IC50 4094.58 nM 10.6019/CHEMBL1201861
Homo sapiens TE-10 IC50 1281.4 nM 10.6019/CHEMBL1201861
Homo sapiens TE-11 IC50 1071.54 nM 10.6019/CHEMBL1201861
Homo sapiens TE-12 IC50 611.99 nM 10.6019/CHEMBL1201861
Homo sapiens TE-15 IC50 1537.48 nM 10.6019/CHEMBL1201861
Homo sapiens TE-441-T IC50 994.34 nM 10.6019/CHEMBL1201861
Homo sapiens TE-5 IC50 31334.82 nM 10.6019/CHEMBL1201861
Homo sapiens TE-6 IC50 1648.33 nM 10.6019/CHEMBL1201861
Homo sapiens TE-8 IC50 1679.0 nM 10.6019/CHEMBL1201861
Homo sapiens TE-9 IC50 6725.01 nM 10.6019/CHEMBL1201861
Homo sapiens Testis-specific serine/threonine-protein kinase 1 Kd 4800.0 nM 10.1038/nbt1358
Homo sapiens Testis-specific serine/threonine-protein kinase 1 Kd 4800.0 nM 10.1038/nbt.1990
Homo sapiens Testis-specific serine/threonine-protein kinase 1 Kd 4800.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Testis-specific serine/threonine-protein kinase 1 Residual Activity 6.0 % 10.1042/bj20121418
Homo sapiens Testis-specific serine/threonine-protein kinase 1 Residual Activity 15.0 % 10.1042/bj20121418
Homo sapiens Testis-specific serine/threonine-protein kinase 2 Residual Activity 30.0 % 10.1042/bj20121418
Homo sapiens Testis-specific serine/threonine-protein kinase 2 Residual Activity 51.0 % 10.1042/bj20121418
Homo sapiens TGBC1TKB IC50 3175.57 nM 10.6019/CHEMBL1201861
Homo sapiens TGBC24TKB IC50 5200.55 nM 10.6019/CHEMBL1201861
Homo sapiens TGF-beta receptor type I Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens TGF-beta receptor type I Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens TGF-beta receptor type I Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens TGF-beta receptor type I Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TGF-beta receptor type I Residual Activity 81.0 % 10.1042/bj20121418
Homo sapiens TGF-beta receptor type I Residual Activity 85.0 % 10.1042/bj20121418
Homo sapiens TGF-beta receptor type II Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens TGF-beta receptor type II Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens TGF-beta receptor type II Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens TGF-beta receptor type II Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TGW IC50 52828.72 nM 10.6019/CHEMBL1201861
Homo sapiens THP-1 IC50 12074.77 nM 10.6019/CHEMBL1201861
Homo sapiens TK-10 IC50 391.44 nM 10.6019/CHEMBL1201861
Homo sapiens TP53-regulating kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TRAF2- and NCK-interacting kinase Kd 1600.0 nM 10.1038/nbt1358
Homo sapiens TRAF2- and NCK-interacting kinase Kd 1600.0 nM 10.1038/nbt.1990
Homo sapiens TRAF2- and NCK-interacting kinase Kd 1600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens TRAF2- and NCK-interacting kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Transient receptor potential cation channel subfamily M member 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens TT IC50 20241.52 nM 10.6019/CHEMBL1201861
Homo sapiens TUR IC50 413.74 nM 10.6019/CHEMBL1201861
Homo sapiens TYK-nu IC50 40395.32 nM 10.6019/CHEMBL1201861
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine kinase non-receptor protein 2 Kd 120.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine kinase non-receptor protein 2 Kd 120.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine kinase non-receptor protein 2 Kd 303.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine kinase non-receptor protein 2 Residual Activity -1.0 % 10.1042/bj20121418
Homo sapiens Tyrosine kinase non-receptor protein 2 Residual Activity 11.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase ABL Kd 790.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 3100.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 3200.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 3200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL Kd 4900.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 5600.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase ABL Residual Activity 81.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase ABL Residual Activity 89.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase ABL2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ABL2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase ABL2 Residual Activity 45.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase ABL2 Residual Activity 77.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase BLK Kd 500.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BLK Kd 500.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase BLK Kd 500.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase BLK Residual Activity 5.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase BLK Residual Activity 7.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase BMX Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BMX Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase BMX Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase BMX Residual Activity 10.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase BMX Residual Activity 12.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase BRK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BRK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase BRK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase BRK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase BRK Residual Activity 93.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase BRK Residual Activity 98.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase BTK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BTK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase BTK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase BTK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase BTK Residual Activity 35.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase BTK Residual Activity 60.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase CSK Kd 8700.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase CSK Kd 8700.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase CSK Kd 8700.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase CSK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase CSK Residual Activity 78.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase CSK Residual Activity 82.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase CTK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase CTK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FER Kd 1200.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FER Kd 1200.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FER Kd 1200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FER Kd 2985.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FER Residual Activity 14.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase FER Residual Activity 26.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase FES Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FES Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FES Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FES Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FES Residual Activity 9.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase FES Residual Activity 15.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase FGR Kd 730.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FGR Kd 730.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FGR Kd 730.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FGR Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase FGR Residual Activity 7.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase FRK Kd 2400.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FRK Kd 2400.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FRK Kd 2400.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FRK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FRK Residual Activity 23.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase FRK Residual Activity 33.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase FYN Kd 2100.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FYN Kd 2100.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FYN Kd 2100.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase FYN Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FYN Residual Activity 6.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase FYN Residual Activity 10.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase HCK Kd 720.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase HCK Kd 720.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase HCK Kd 720.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase HCK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase HCK Residual Activity 5.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase HCK Residual Activity 7.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase HCK Residual Activity 12.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase HCK Residual Activity 13.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase ITK/TSK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ITK/TSK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ITK/TSK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ITK/TSK Residual Activity 31.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase ITK/TSK Residual Activity 56.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase JAK1 Kd 670.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase JAK1 Kd 670.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase JAK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase JAK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase JAK1 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase JAK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase JAK2 Kd 94.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase JAK2 Kd 94.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase JAK2 Kd 94.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase JAK2 Residual Activity 2.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase JAK2 Residual Activity 7.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase JAK3 Kd 12.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase JAK3 Kd 12.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase JAK3 Kd 12.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase JAK3 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase LCK Kd 280.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase LCK Kd 280.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase LCK Kd 280.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase LCK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase LCK Residual Activity 5.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase LCK Residual Activity 6.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase LCK Residual Activity 13.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase Lyn Kd 4200.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase Lyn Kd 4200.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase Lyn Kd 4200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase Lyn Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase Lyn Residual Activity 2.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase Lyn Residual Activity 6.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase receptor FLT3 GI50 38.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Tyrosine-protein kinase receptor FLT3 GI50 55.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Tyrosine-protein kinase receptor FLT3 GI50 400.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 1.0 nM 10.1021/acs.jmedchem.0c00696
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 13.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 15.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 30.0 nM 10.1016/j.ejmech.2019.111710
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 37.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 40.0 nM 10.1021/acs.jmedchem.9b01229
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 501.0 nM 10.1016/j.ejmech.2020.112205
Homo sapiens Tyrosine-protein kinase receptor FLT3 IC50 528.0 nM 10.1016/j.bmc.2021.116596
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 2.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 2.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 6.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 6.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 6.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 6.8 nM 10.1021/acs.jmedchem.8b01714
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 6.8 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 6.8 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 6.8 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 11.0 nM 10.1016/j.ejmech.2019.06.002
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 11.0 nM 10.1021/acs.jmedchem.8b01714
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 11.0 nM 10.1021/jm401094t
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 11.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 11.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 11.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 12.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 15.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 15.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 15.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 341.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd nan None 10.1021/acs.jmedchem.8b01714
Homo sapiens Tyrosine-protein kinase receptor FLT3 Residual Activity 0.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase receptor FLT3 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase receptor FLT3 Selectivity 0.0764 None 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor RET Kd 20.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor RET Kd 20.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor RET Kd 27.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor RET Kd 27.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor RET Kd 130.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor RET Kd 130.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor RET Kd 130.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor RET Kd 350.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor RET Kd 350.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor RET Kd 350.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor RET Kd 19822.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase receptor RET Residual Activity 5.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase receptor RET Residual Activity 8.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase receptor Tie-1 Kd 1400.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor Tie-1 Kd 1400.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor Tie-1 Kd 1400.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Kd 88.0 nM 10.1016/j.ejmech.2019.06.002
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Residual Activity 83.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Residual Activity 84.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase receptor UFO Kd 620.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor UFO Kd 620.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor UFO Kd 620.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase receptor UFO Residual Activity 9.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase receptor UFO Residual Activity 14.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase SRC Kd 1200.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase SRC Kd 1200.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase SRC Kd 1200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase SRC Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase SRC Residual Activity 24.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase SRC Residual Activity 40.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase Srms Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase Srms Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase Srms Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase SYK Kd 88.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase SYK Kd 88.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase SYK Kd 88.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase SYK Kd 9226.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase SYK Residual Activity 2.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase SYK Residual Activity 3.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase TEC Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TEC Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TEC Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase TEC Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase TEC Residual Activity 40.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase TEC Residual Activity 85.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase TIE-2 Kd 1900.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TIE-2 Kd 1900.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TIE-2 Kd 1900.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase TIE-2 Residual Activity 73.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase TIE-2 Residual Activity 133.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase TXK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TXK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TXK Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase TXK Residual Activity 69.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase TXK Residual Activity 82.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase TYK2 Kd 250.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TYK2 Kd 250.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TYK2 Kd 250.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase TYK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TYK2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase TYK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase YES Kd 950.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase YES Kd 950.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase YES Kd 950.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase YES Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase YES Potency 109.1 nM None
Homo sapiens Tyrosine-protein kinase YES Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase YES Residual Activity 5.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase ZAP-70 Kd 2600.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ZAP-70 Kd 2600.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ZAP-70 Kd 2600.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Tyrosine-protein kinase ZAP-70 Residual Activity 60.0 % 10.1042/bj20121418
Homo sapiens Tyrosine-protein kinase ZAP-70 Residual Activity 70.0 % 10.1042/bj20121418
Homo sapiens Tyrosyl-tRNA synthetase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens U-118-MG IC50 11277.94 nM 10.6019/CHEMBL1201861
Homo sapiens U-251 IC50 616.21 nM 10.6019/CHEMBL1201861
Homo sapiens U-266 IC50 983.02 nM 10.6019/CHEMBL1201861
Homo sapiens U2OS IC50 1169.96 nM 10.6019/CHEMBL1201861
Homo sapiens U5 small nuclear ribonucleoprotein 200 kDa helicase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens U-698-M IC50 55317.32 nM 10.6019/CHEMBL1201861
Homo sapiens U-87 MG IC50 2681.24 nM 10.6019/CHEMBL1201861
Homo sapiens U-937 GI50 1400.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens U-937 GI50 1400.0 nM 10.1021/acs.jmedchem.9b01229
Homo sapiens UACC-257 IC50 3818.44 nM 10.6019/CHEMBL1201861
Homo sapiens UACC-62 IC50 4257.64 nM 10.6019/CHEMBL1201861
Homo sapiens UACC-812 IC50 154215.04 nM 10.6019/CHEMBL1201861
Homo sapiens UACC-893 IC50 47373.55 nM 10.6019/CHEMBL1201861
Homo sapiens UMC-11 IC50 1782.78 nM 10.6019/CHEMBL1201861
Homo sapiens UMUC3 IC50 1006.89 nM 10.6019/CHEMBL1201861
Homo sapiens Uncharacterized aarF domain-containing protein kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Uncharacterized aarF domain-containing protein kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Uncharacterized aarF domain-containing protein kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Uncharacterized aarF domain-containing protein kinase 4 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Uncharacterized protein FLJ45252 Kd 293.0 nM 10.1126/science.aan4368
Homo sapiens UO-31 IC50 196.98 nM 10.6019/CHEMBL1201861
Homo sapiens VA-ES-BJ IC50 248.83 nM 10.6019/CHEMBL1201861
Homo sapiens Vascular endothelial growth factor receptor 1 Kd 450.0 nM 10.1038/nbt1358
Homo sapiens Vascular endothelial growth factor receptor 1 Kd 450.0 nM 10.1038/nbt.1990
Homo sapiens Vascular endothelial growth factor receptor 1 Kd 450.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Vascular endothelial growth factor receptor 1 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Vascular endothelial growth factor receptor 1 Residual Activity 4.0 % 10.1042/bj20121418
Homo sapiens Vascular endothelial growth factor receptor 2 IC50 250.0 nM 10.1016/j.ejmech.2015.05.008
Homo sapiens Vascular endothelial growth factor receptor 2 Kd 3200.0 nM 10.1038/nbt1358
Homo sapiens Vascular endothelial growth factor receptor 2 Kd 3200.0 nM 10.1038/nbt.1990
Homo sapiens Vascular endothelial growth factor receptor 2 Kd 3200.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Vascular endothelial growth factor receptor 2 Residual Activity 2.0 % 10.1042/bj20121418
Homo sapiens Vascular endothelial growth factor receptor 2 Residual Activity 3.0 % 10.1042/bj20121418
Homo sapiens Vascular endothelial growth factor receptor 3 Kd 670.0 nM 10.1038/nbt1358
Homo sapiens Vascular endothelial growth factor receptor 3 Kd 670.0 nM 10.1038/nbt.1990
Homo sapiens Vascular endothelial growth factor receptor 3 Kd 670.0 nM 10.1182/blood-2009-05-222034
Homo sapiens Vascular endothelial growth factor receptor 3 Residual Activity 1.0 % 10.1042/bj20121418
Homo sapiens Vascular endothelial growth factor receptor 3 Residual Activity 3.0 % 10.1042/bj20121418
Homo sapiens Very long-chain specific acyl-CoA dehydrogenase, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens VM-CUB-1 IC50 736.7 nM 10.6019/CHEMBL1201861
Homo sapiens VMRC-RCZ IC50 369.35 nM 10.6019/CHEMBL1201861
Homo sapiens Wee1-like protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Wee1-like protein kinase 2 Kd 10000.0 nM 10.1182/blood-2009-05-222034
Homo sapiens WM-115 IC50 2359.68 nM 10.6019/CHEMBL1201861
Homo sapiens WSU-NHL IC50 1391.85 nM 10.6019/CHEMBL1201861
Homo sapiens YAPC IC50 37009.85 nM 10.6019/CHEMBL1201861
Homo sapiens YKG-1 IC50 195.68 nM 10.6019/CHEMBL1201861
Homo sapiens YT IC50 262.82 nM 10.6019/CHEMBL1201861
Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 416.0 nM 10.1021/acs.jmedchem.0c01467
Mus musculus BaF3 GI50 10.0 nM 10.1039/d2md00067a
Mus musculus BaF3 GI50 100.0 nM 10.1039/d2md00067a
Mus musculus BaF3 GI50 540.0 nM 10.1021/acs.jmedchem.9b01229
Mus musculus BaF3 IC50 4.14 nM 10.1021/acs.jmedchem.0c00696
Mus musculus BaF3 IC50 10.0 nM 10.1039/d2md00067a
Mus musculus BaF3 IC50 200.0 nM 10.1021/jm2006222
Mus musculus HT-22 IC50 1000.0 nM 10.1021/acs.jmedchem.2c02068
Mus musculus Mus musculus AUC 1426.62 ng.hr.mL-1 10.1182/blood-2009-05-222034
Mus musculus Mus musculus Cmax 770.0 nM 10.1182/blood-2009-05-222034
Mus musculus Mus musculus Tmax 0.67 hr 10.1182/blood-2009-05-222034
Mycobacterium tuberculosis Serine/threonine-protein kinase pknB Kd 10000.0 nM 10.1038/nbt.1990
Plasmodium falciparum Calcium-dependent protein kinase 1 Kd 950.0 nM 10.1038/nbt.1990
Plasmodium falciparum (isolate 3D7) Cell division control protein 2 homolog Kd 10000.0 nM 10.1038/nbt.1990
Rattus norvegicus Tubulin alpha-1 chain Kd 3100.0 nM 10.1038/nbt1358
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 11.93 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 19.68 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Activity nan None 10.1038/s41586-020-2286-9
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 AUC 506.4 None 10.1038/s41586-020-2286-9
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Hit score -0.02037 None 10.1101/2020.04.21.054387
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 336.51 nM 10.1038/s41586-020-2286-9
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -37.43 % 10.21203/rs.3.rs-23951/v1
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 0.11 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 0.12 % 10.6019/CHEMBL4495565
None ADMET Activity nan None 10.1021/acs.jmedchem.8b01594
None ADMET AUC Ratio 0.2848 None 10.1038/s41586-020-2286-9
None ADMET T1/2 20.0 hr 10.1021/acsmedchemlett.0c00202
None BC1 cell line IC50 565.58 nM 10.6019/CHEMBL1201861
None Unchecked Activity 80.0 % 10.1021/acs.jmedchem.9b00196
None Unchecked Activity nan None 10.1021/acs.jmedchem.8b01594
None Unchecked Activity nan None 10.1021/acsmedchemlett.0c00202
None Unchecked CC50 400.0 nM 10.1021/acs.jmedchem.0c01467
None Unchecked GI50 16.0 nM 10.1021/acs.jmedchem.9b01229
None Unchecked GI50 43.0 nM 10.1021/acs.jmedchem.9b01229
None Unchecked GI50 47.0 nM 10.1021/acs.jmedchem.9b01229
None Unchecked GI50 94900.0 nM 10.1021/acs.jmedchem.8b01594
None Unchecked GI50 10000000.0 nM 10.1021/acs.jmedchem.8b01594
None Unchecked IC50 10.0 nM 10.1016/j.ejmech.2019.06.002
None Unchecked IC50 10.0 nM 10.1021/acsmedchemlett.0c00202
None Unchecked IC50 50.0 nM 10.1021/acsmedchemlett.0c00202
None Unchecked IC50 200.0 nM 10.1016/j.bmc.2010.01.056
None Unchecked IC50 500.0 nM 10.1021/acs.jmedchem.1c02079
None Unchecked Inhibition nan % 10.1021/jm201265f
None Unchecked Kd 11.0 nM 10.1182/blood-2009-05-222034
None Unchecked Kd 620.0 nM 10.1182/blood-2009-05-222034
None Unchecked Kd 1700.0 nM 10.1182/blood-2009-05-222034
None Unchecked Kd 1800.0 nM 10.1182/blood-2009-05-222034
None Unchecked Kd 1900.0 nM 10.1182/blood-2009-05-222034
None Unchecked Kd 7000.0 nM 10.1182/blood-2009-05-222034
None Unchecked Kd 30000.0 nM 10.1126/science.aan4368
None Unchecked logIC50 2.29 None 10.1016/j.bmc.2010.01.056
None Unchecked Potency 234.8 nM None
None Unchecked Potency 468.6 nM None
None Unchecked Potency 742.7 nM None
None Unchecked Potency 935.0 nM None
None Unchecked Potency 1049.0 nM None
None Unchecked Potency 2093.1 nM None
None Unchecked Potency 5899.2 nM None
None Unchecked Ratio IC50 1.4 None 10.1016/j.bmc.2010.01.056
None Unchecked Ratio IC50 1.54 None 10.1021/acs.jmedchem.2c02068
None Unchecked Ratio IC50 2.3 None 10.1021/acs.jmedchem.2c02068
None Unchecked Ratio IC50 5.23 None 10.1021/acs.jmedchem.2c02068
None Unchecked Ratio IC50 20.0 None 10.1021/acs.jmedchem.0c02247

Metabolism Information