None
AlkaPlorer ID: AK323902
Synonym: None
IUPAC Name: [(2R,3R,5R,8R,10R,12S)-12-hydroxy-5,10,15-trimethyl-14-oxo-4,9-dioxa-13-azatetracyclo[10.3.0.03,5.08,10]pentadec-1(15)-en-2-yl] (E)-2-methylbut-2-enoate
Structure
SMILES: C/C=C(\C)C(=O)O[C@@H]1C2=C(C)C(O)=N[C@]2(O)C[C@@]2(C)O[C@@H]2CC[C@@]2(C)O[C@H]12
InChI: InChI=1S/C20H27NO6/c1-6-10(2)17(23)25-14-13-11(3)16(22)21-20(13,24)9-19(5)12(26-19)7-8-18(4)15(14)27-18/h6,12,14-15,24H,7-9H2,1-5H3,(H,21,22)/b10-6+/t12-,14-,15-,18-,19-,20+/m1/s1
InChIKey: XFPKBESLGWGFJQ-DSUMSCBMSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Salvia scapiformis | Salvia | Lamiaceae | Lamiales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 377.4370000000002
TPSA？: 104.18
MolLogP？: 2.3385000000000007
Number of H-Donors: 2
Number of H-Acceptors: 6
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | HUVEC | Inhibition | nan | % | 10.1021/acs.jnatprod.9b00648 |
| Homo sapiens | Vascular endothelial growth factor receptor 2 | IC50 | 40400.0 | nM | 10.1021/acs.jnatprod.9b00648 |
| Homo sapiens | Vascular endothelial growth factor receptor 2 | Inhibition | nan | % | 10.1021/acs.jnatprod.9b00648 |