None
AlkaPlorer ID: AK323956
Synonym: None
IUPAC Name: 2-amino-3,5-dihydropyrrolo[2,3-d]pyrimidin-4-one
Structure
SMILES: N=C1N=C(O)C2=C(N=CC2)N1
InChI: InChI=1S/C6H6N4O/c7-6-9-4-3(1-2-8-4)5(11)10-6/h2H,1H2,(H3,7,9,10,11)
InChIKey: LOSIULRWFAEMFL-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Streptomyces sp. | Streptomyces | Streptomycetaceae | Kitasatosporales | Actinomycetes | Actinomycetota | None | Bacteria |
Properties Information
Molecule Weight: 150.141
TPSA？: 85.12
MolLogP？: -0.14683
Number of H-Donors: 3
Number of H-Acceptors: 4
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bos taurus | Xanthine dehydrogenase | Ki | 3000.0 | nM | 10.1021/jm00374a008 |
| Homo sapiens | Rho-associated protein kinase 1 | Activity | 68.0 | % | 10.1016/j.bmcl.2010.11.060 |
| Leishmania major | Pteridine reductase 1 | Ki | 27000.0 | nM | 10.1021/jm901059x |
| Ricinus communis | Ricin | IC50 | 2800000.0 | nM | 10.1021/jm010186s |
| None | Unchecked | IC50 | 35.0 | ug.mL-1 | 10.1021/np50077a014 |
| None | Unchecked | IC50 | 2000000.0 | nM | 10.1021/jm010186s |
| None | Unchecked | Ki | 35000.0 | nM | 10.1021/jm901059x |