Incarxanthone D
AlkaPlorer ID: AK324505
Synonym: None
IUPAC Name: (1R,13R,16R)-1,5,16-trihydroxy-10-oxa-14-azatetracyclo[11.2.1.02,11.04,9]hexadeca-2(11),4,6,8-tetraene-3,15-dione
Structure
SMILES: O=C1N[C@@H]2CC3=C(C(=O)C4=C(O)C=CC=C4O3)[C@@]1(O)[C@@H]2O
InChI: InChI=1S/C14H11NO6/c16-6-2-1-3-7-9(6)11(17)10-8(21-7)4-5-12(18)14(10,20)13(19)15-5/h1-3,5,12,16,18,20H,4H2,(H,15,19)/t5-,12-,14-/m1/s1
InChIKey: QPCOTBRTYCZCGH-DKEGVVEDSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Peniophora incarnata | Peniophora | Peniophoraceae | Russulales | Agaricomycetes | Basidiomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 289.243
TPSA？: 120.0
MolLogP？: -0.8984000000000003
Number of H-Donors: 4
Number of H-Acceptors: 6
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | A-375 | IC50 | 10000.0 | nM | 10.1021/acs.jnatprod.0c00523 |
| Homo sapiens | HL-60 | IC50 | 10000.0 | nM | 10.1021/acs.jnatprod.0c00523 |
| Homo sapiens | MCF7 | IC50 | 10000.0 | nM | 10.1021/acs.jnatprod.0c00523 |