Incarxanthone F
AlkaPlorer ID: AK324506
Synonym: None
IUPAC Name: methyl 8-hydroxy-9-oxo-2-[[(1R,2R,3R)-1,2,8-trihydroxy-1-methoxycarbonyl-9-oxo-3,4-dihydro-2H-xanthen-3-yl]amino]xanthene-1-carboxylate
Structure
SMILES: COC(=O)C1=C(N[C@@H]2CC3=C(C(=O)C4=C(O)C=CC=C4O3)[C@](O)(C(=O)OC)[C@@H]2O)C=CC2=C1C(=O)C1=C(O)C=CC=C1O2
InChI: InChI=1S/C30H23NO12/c1-40-28(37)20-12(9-10-18-23(20)25(34)21-14(32)5-3-7-16(21)42-18)31-13-11-19-24(30(39,27(13)36)29(38)41-2)26(35)22-15(33)6-4-8-17(22)43-19/h3-10,13,27,31-33,36,39H,11H2,1-2H3/t13-,27-,30-/m1/s1
InChIKey: SETPGQKQIHMBAF-ZHEHGQCCSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Peniophora incarnata | Peniophora | Peniophoraceae | Russulales | Agaricomycetes | Basidiomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 589.5090000000004
TPSA？: 205.97
MolLogP？: 2.0087
Number of H-Donors: 5
Number of H-Acceptors: 13
RingCount: 6
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | A-375 | IC50 | 10000.0 | nM | 10.1021/acs.jnatprod.0c00523 |
| Homo sapiens | HL-60 | IC50 | 10000.0 | nM | 10.1021/acs.jnatprod.0c00523 |
| Homo sapiens | MCF7 | IC50 | 10000.0 | nM | 10.1021/acs.jnatprod.0c00523 |