None
AlkaPlorer ID: AK324788
Synonym: None
IUPAC Name: 2-[(2R)-9,10,14-trimethyl-4-oxo-3-azatricyclo[7.3.2.02,6]tetradeca-5,13-dien-3-yl]acetic acid
Structure
SMILES: CC1=CC2CCC(C)C1(C)CCC1=CC(=O)N(CC(=O)O)[C@@H]12
InChI: InChI=1S/C18H25NO3/c1-11-4-5-13-8-12(2)18(11,3)7-6-14-9-15(20)19(17(13)14)10-16(21)22/h8-9,11,13,17H,4-7,10H2,1-3H3,(H,21,22)/t11?,13?,17-,18?/m1/s1
InChIKey: PIWAJVIRUDUXKZ-UMVQVTCQSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Lamellodysidea herbacea | Lamellodysidea | Dysideidae | Dictyoceratida | Demospongiae | Porifera | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 303.402
TPSA？: 57.61
MolLogP？: 3.000700000000001
Number of H-Donors: 1
Number of H-Acceptors: 2
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Tumour suppressor p53/oncoprotein Mdm2 | Inhibition | None | % | 10.1021/acs.jnatprod.7b00610 |
| Homo sapiens | Ubiquitin carboxyl-terminal hydrolase 7 | Inhibition | None | % | 10.1021/acs.jnatprod.7b00610 |
| Homo sapiens | Ubiquitin-like modifier-activating enzyme 1 | Inhibition | None | % | 10.1021/acs.jnatprod.7b00610 |
| None | Macrophage | Inhibition | None | % | 10.1021/acs.jnatprod.7b00610 |
| None | Unchecked | Inhibition | None | % | 10.1021/acs.jnatprod.7b00610 |