Cladodionen
AlkaPlorer ID: AK326522
Synonym: None
IUPAC Name: 3-(2-methyl-2,3-dihydropyran-6-ylidene)-5-propan-2-ylidenepyrrolidine-2,4-dione
Structure
SMILES: CC(C)=C1N=C(O)C(=C2C=CCC(C)O2)C1=O
InChI: InChI=1S/C13H15NO3/c1-7(2)11-12(15)10(13(16)14-11)9-6-4-5-8(3)17-9/h4,6,8H,5H2,1-3H3,(H,14,16)
InChIKey: SICSPZGTMAHWBZ-UHFFFAOYSA-N
Reference
Cladodionen, a Cytotoxic Hybrid Polyketide from the Marine-Derived Cladosporium sp. OUCMDZ-1635
PubChem CID: 139590582
LOTUS: LTS0192177
COCONUT: CNP0072598.2
{NPAtlas: NPA023298
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Cladosporium sp. OUCMDZ-1635 | Cladosporium | Cladosporiaceae | Cladosporiales | Dothideomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 233.267
TPSA？: 58.89000000000001
MolLogP？: 2.438600000000001
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Acinetobacter baumannii | Acinetobacter baumannii | MIC | 100000.0 | nM | 10.1016/j.ejmech.2020.112159 |
| Enterococcus faecalis | Enterococcus faecalis | MIC | nan | None | 10.1016/j.ejmech.2020.112159 |
| Mus musculus | L5178Y | Activity | 0.0 | % | 10.1016/j.ejmech.2020.112159 |
| Mus musculus | L5178Y | EC50 | 3700.0 | nM | 10.1016/j.ejmech.2020.112159 |
| Mycobacterium tuberculosis | Mycobacterium tuberculosis | MIC | 100000.0 | nM | 10.1016/j.ejmech.2020.112159 |
| Ustilago maydis | Ustilago maydis | IZ | 9.7 | mm | 10.1016/j.ejmech.2020.112159 |
| None | Unchecked | MIC | 100000.0 | nM | 10.1016/j.ejmech.2020.112159 |
| None | Unchecked | MIC | nan | None | 10.1016/j.ejmech.2020.112159 |