(8R)-4,8-dimethoxy-8-(3-methylbut-2-en-1-yl)furo[2,3-b]quinolin-7-one
AlkaPlorer ID: AK334399
Synonym: None
IUPAC Name: 4,8-dimethoxy-8-(3-methylbut-2-enyl)furo[2,3-b]quinolin-7-one
Structure
SMILES: COC1=C2C=COC2=NC2=C1C=CC(=O)C2(CC=C(C)C)OC
InChI: InChI=1S/C18H19NO4/c1-11(2)7-9-18(22-4)14(20)6-5-12-15(21-3)13-8-10-23-17(13)19-16(12)18/h5-8,10H,9H2,1-4H3
InChIKey: AOCCRKXUBBAOQI-UHFFFAOYSA-N
Reference
Components of Haplophyllum latifolium
PubChem CID: 3110227
CAS: 59557-95-8
LOTUS: LTS0203394
COCONUT: CNP0185989.2
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Haplophyllum acutifolium | Haplophyllum | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 313.35300000000007
TPSA？: 61.56
MolLogP？: 3.6303000000000014
Number of H-Donors: 0
Number of H-Acceptors: 5
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Aldehyde dehydrogenase 1A1 | Potency | 44668.4 | nM | None |
| Homo sapiens | DNA polymerase iota | Potency | 89125.1 | nM | None |
| Homo sapiens | HepG2 | Potency | 112.2 | nM | None |
| Homo sapiens | Parathyroid hormone receptor | Potency | 35481.3 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 25929.0 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 29092.9 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 10417.9 | nM | None |