1-(10H-phenothiazin-10-ylcarbonyl)piperidine-4-carboxamide
AlkaPlorer ID: AK345791
Synonym: None
IUPAC Name: 1-(phenothiazine-10-carbonyl)piperidine-4-carboxamide
Structure
SMILES: NC(=O)C1CCN(C(=O)N2C3=CC=CC=C3SC3=CC=CC=C32)CC1
InChI: InChI=1S/C19H19N3O2S/c20-18(23)13-9-11-21(12-10-13)19(24)22-14-5-1-3-7-16(14)25-17-8-4-2-6-15(17)22/h1-8,13H,9-12H2,(H2,20,23)
InChIKey: BOJKPZJBTFHKKG-UHFFFAOYSA-N
Reference
Cytotoxic Indolocarbazoles from<i>Actinomadura melliaura</i>ATCC 39691
PubChem CID: 1389785
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 353.4470000000002
TPSA？: 66.64
MolLogP？: 3.606600000000002
Number of H-Donors: 1
Number of H-Acceptors: 3
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Equus caballus | Ferritin light chain | Potency | 25118.9 | nM | None |
| Homo sapiens | Aldehyde dehydrogenase 1A1 | Potency | 39810.7 | nM | None |
| Homo sapiens | FAD-linked sulfhydryl oxidase ALR | AC50 | 10780.0 | nM | None |
| Homo sapiens | HepG2 | Potency | 15848.9 | nM | None |
| Homo sapiens | Prelamin-A/C | Potency | 35481.3 | nM | None |
| Homo sapiens | Survival motor neuron protein | Potency | 446.7 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 11689.1 | nM | None |
| Trypanosoma cruzi | Cruzipain | Potency | 39810.7 | nM | None |