4-methoxy-N-(3-methylphenyl)benzamide
AlkaPlorer ID: AK368109
Synonym: None
IUPAC Name: 4-methoxy-N-(3-methylphenyl)benzamide
Structure
SMILES: COC1=CC=C(C(=O)NC2=CC=CC(C)=C2)C=C1
InChI: InChI=1S/C15H15NO2/c1-11-4-3-5-13(10-11)16-15(17)12-6-8-14(18-2)9-7-12/h3-10H,1-2H3,(H,16,17)
InChIKey: DOEUHYAIQRIZIY-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 241.29
TPSA？: 38.33
MolLogP？: 3.255920000000001
Number of H-Donors: 1
Number of H-Acceptors: 2
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | ATPase family AAA domain-containing protein 5 | Potency | 1995.3 | nM | None |
| Homo sapiens | ATPase family AAA domain-containing protein 5 | Potency | 2059.6 | nM | None |
| Homo sapiens | Cellular tumor antigen p53 | Potency | 5011.9 | nM | None |
| Homo sapiens | Cellular tumor antigen p53 | Potency | 6309.6 | nM | None |
| Homo sapiens | Chromobox protein homolog 1 | Potency | 89125.1 | nM | None |
| Homo sapiens | DNA polymerase iota | Potency | 31622.8 | nM | None |
| Homo sapiens | microRNA 21 | Potency | 414.0 | nM | None |
| Homo sapiens | Niemann-Pick C1 protein | Potency | 1258.9 | nM | None |
| Homo sapiens | Nuclear factor NF-kappa-B complex | EC50 | 6194.0 | nM | None |
| Homo sapiens | Ras-related protein Rab-9A | Potency | 1258.9 | nM | None |
| Homo sapiens | Survival motor neuron protein | Potency | 11220.2 | nM | None |
| Leishmania mexicana | Pyruvate kinase | Potency | 14125.4 | nM | None |
| Photinus pyralis | Luciferin 4-monooxygenase | EC50 | 16062.0 | nM | None |
| Photinus pyralis | Luciferin 4-monooxygenase | Potency | 3380.8 | nM | None |
| Photinus pyralis | Luciferin 4-monooxygenase | Potency | 6309.6 | nM | None |
| Photuris pennsylvanica | Luciferase | Potency | 10000.0 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 2332.3 | nM | None |
| Plasmodium falciparum | Plasmodium falciparum | Potency | 9285.0 | nM | None |
| None | ADMET | Activity | -1.7 | % | 10.1016/j.bmc.2010.06.034 |
| None | Molecular identity unknown | Activity | 100.8 | % | 10.1016/j.bmc.2010.06.034 |
| None | Unchecked | EC50 | 7085.0 | nM | None |
| None | Unchecked | Potency | 4466.8 | nM | None |
| None | Unchecked | Potency | 5011.9 | nM | None |