(2R)-5-hydroxy-11-methyl-2-(1,2,3-trihydroxypropan-2-yl)-1H,2H-furo[2,3-c]acridin-6-one
AlkaPlorer ID: AK388501
Synonym: None
IUPAC Name: 5-hydroxy-11-methyl-2-(1,2,3-trihydroxypropan-2-yl)-1,2-dihydrofuro[2,3-c]acridin-6-one
Structure
SMILES: CN1C2=CC=CC=C2C(=O)C2=C(O)C=C3OC(C(O)(CO)CO)CC3=C21
InChI: InChI=1S/C19H19NO6/c1-20-12-5-3-2-4-10(12)18(24)16-13(23)7-14-11(17(16)20)6-15(26-14)19(25,8-21)9-22/h2-5,7,15,21-23,25H,6,8-9H2,1H3
InChIKey: GJDBWKOONRHBIM-UHFFFAOYSA-N
Reference
Gravacridondiolacetate, A New Dihydrofuroacridone Alkaloid from<i>Ruta graveolens</i>
PubChem CID: 21586648
LOTUS: LTS0127873
COCONUT: CNP0420844.1
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Thamnosma montana | Thamnosma | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 357.36200000000014
TPSA？: 112.15000000000002
MolLogP？: 0.4164999999999997
Number of H-Donors: 4
Number of H-Acceptors: 7
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | A-431 | IC50 | None | None | 10.1021/np800644y |
| Homo sapiens | HeLa | IC50 | None | None | 10.1021/np800644y |
| Homo sapiens | MCF7 | IC50 | None | None | 10.1021/np800644y |