Navigation

name Structure Reference Source Properties Activities Metabolism

(1R,2S)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid

AlkaPlorer ID: AK395396

Synonym: None

IUPAC Name: (1S,2S)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid

Structure

SMILES: N[C@H](C(=O)O)[C@H]1C[C@@H]1C(=O)O

copy

InChI: InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3-,4-/m0/s1

copy

InChIKey: GZOVEPYOCJWRFC-HZLVTQRSSA-N

copy

Source

Species Genus Family Order Class Phylum Kingdom Domain
Blighia sapida Blighia Sapindaceae Sapindales Magnoliopsida Streptophyta Viridiplantae Eukaryota

Properties Information

Molecule Weight: 159.141

TPSA？: 100.62000000000002

MolLogP？: -0.881

Number of H-Donors: 3

Number of H-Acceptors: 3

RingCount: 1

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Homo sapiens Cerebroside-sulfatase Potency 8492.1 nM None
Homo sapiens DNA-(apurinic or apyrimidinic site) lyase Potency 2511.9 nM None
Homo sapiens DNA-(apurinic or apyrimidinic site) lyase Potency 39810.7 nM None
Homo sapiens HEK293 Potency 11.2 nM None
Homo sapiens HEK293 Potency 259.2 nM None
Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Potency 16833.6 nM None
Homo sapiens Metabotropic glutamate receptor 1 Activity 23000.0 nM 10.1021/jm0110486
Homo sapiens Metabotropic glutamate receptor 1 Ki 50000.0 nM 10.1021/jm000007r
Homo sapiens Metabotropic glutamate receptor 2 Activity 300.0 nM 10.1021/jm0110486
Homo sapiens Metabotropic glutamate receptor 2 EC50 380.0 nM 10.1021/jm00009a001
Homo sapiens Metabotropic glutamate receptor 2 Ki 490.0 nM 10.1021/jm000007r
Homo sapiens Metabotropic glutamate receptor 3 Activity 600.0 nM 10.1021/jm0110486
Homo sapiens Metabotropic glutamate receptor 3 Ki 440.0 nM 10.1021/jm000007r
Homo sapiens Metabotropic glutamate receptor 4 Activity 4000.0 nM 10.1021/jm0110486
Homo sapiens Metabotropic glutamate receptor 4 Ki 50000.0 nM 10.1021/jm000007r
Homo sapiens Metabotropic glutamate receptor 5 Activity 17000.0 nM 10.1021/jm0110486
Homo sapiens Metabotropic glutamate receptor 5 Ki 3100.0 nM 10.1021/jm000007r
Homo sapiens Metabotropic glutamate receptor 6 Activity 600.0 nM 10.1021/jm0110486
Homo sapiens Metabotropic glutamate receptor 6 Ki 5800.0 nM 10.1021/jm000007r
Homo sapiens Metabotropic glutamate receptor 7 Activity 47000.0 nM 10.1021/jm0110486
Homo sapiens Metabotropic glutamate receptor 7 Ki 230000.0 nM 10.1021/jm000007r
Homo sapiens Metabotropic glutamate receptor 8 Activity 400.0 nM 10.1021/jm0110486
Homo sapiens Metabotropic glutamate receptor 8 Ki 3400.0 nM 10.1021/jm000007r
Homo sapiens M-phase phosphoprotein 8 Potency 794.3 nM None
Homo sapiens Peripheral myelin protein 22 Potency 84921.4 nM None
Homo sapiens Prelamin-A/C Potency 2.0 nM None
Rattus norvegicus Glutamate NMDA receptor IC50 100000.0 nM 10.1021/jm9606756
Rattus norvegicus Glutamate receptor ionotropic, AMPA IC50 100000.0 nM 10.1021/jm9606756
Rattus norvegicus Glutamate receptor ionotropic, kainate IC50 100000.0 nM 10.1021/jm9606756
Rattus norvegicus Metabotropic glutamate receptor 1 EC50 23000.0 nM 10.1021/jm030967o
Rattus norvegicus Metabotropic glutamate receptor 1 EC50 ratio 5.0 None 10.1021/jm980571q
Rattus norvegicus Metabotropic glutamate receptor 2 EC50 300.0 nM 10.1021/jm030967o
Rattus norvegicus Metabotropic glutamate receptor 2 EC50 750.0 nM 10.1021/jm00009a001
Rattus norvegicus Metabotropic glutamate receptor 2 EC50 ratio 0.04 None 10.1021/jm980571q
Rattus norvegicus Metabotropic glutamate receptor 3 EC50 600.0 nM 10.1021/jm030967o
Rattus norvegicus Metabotropic glutamate receptor 4 EC50 4000.0 nM 10.1021/jm030967o
Rattus norvegicus Metabotropic glutamate receptor 5 EC50 17000.0 nM 10.1021/jm030967o
Rattus norvegicus Metabotropic glutamate receptor 6 EC50 600.0 nM 10.1021/jm030967o
Rattus norvegicus Metabotropic glutamate receptor 7 EC50 47000.0 nM 10.1021/jm030967o
Rattus norvegicus Metabotropic glutamate receptor 8 EC50 400.0 nM 10.1021/jm030967o
Rattus norvegicus Rattus norvegicus EC50 1100.0 nM 10.1021/jm9606756
Rattus norvegicus Rattus norvegicus EC50 25400.0 nM 10.1021/jm9606756
Rattus norvegicus Rattus norvegicus IC50 700.0 nM 10.1021/jm9502908
Rattus norvegicus Rattus norvegicus Relative potency 6.0 None 10.1021/jm9502908
None No relevant target pKa 1.9 None 10.1021/jm9502908
None No relevant target pKa 4.2 None 10.1021/jm9502908
None No relevant target pKa 9.7 None 10.1021/jm9502908
None Unchecked IC50 100.0 nM 10.1021/jm9502908
None Unchecked IC50 454.0 nM 10.1021/jm9606756
None Unchecked Inhibition nan % 10.1038/nchembio873
None Unchecked Potency 11.2 nM None
None Unchecked Potency 158.5 nM None
None Unchecked Potency 707.9 nM None

Metabolism Information