8-Piperidinomethyl-7-hydroxycoumarin
AlkaPlorer ID: AK396734
Synonym: None
IUPAC Name: 7-hydroxy-8-(piperidin-1-ylmethyl)chromen-2-one
Structure
SMILES: O=C1C=CC2=CC=C(O)C(CN3CCCCC3)=C2O1
InChI: InChI=1S/C15H17NO3/c17-13-6-4-11-5-7-14(18)19-15(11)12(13)10-16-8-2-1-3-9-16/h4-7,17H,1-3,8-10H2
InChIKey: HCOQDCSXZLTSRQ-UHFFFAOYSA-N
Reference
PubChem CID: 10923235
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 259.3049999999999
TPSA？: 53.68
MolLogP？: 2.4845000000000006
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bovine viral diarrhea virus 1 | Bovine viral diarrhea virus 1 | EC50 | 100000.0 | nM | 10.1016/j.bmc.2007.11.045 |
| Coxsackievirus B2 | Coxsackievirus B2 | Activity | nan | None | 10.1016/j.bmc.2007.11.045 |
| Glycine max | Seed lipoxygenase-1 | IC50 | 37000.0 | nM | 10.1021/jm0580149 |
| Homo sapiens | MT4 | CC50 | 100000.0 | nM | 10.1016/j.bmc.2007.11.045 |
| Human immunodeficiency virus 1 | Human immunodeficiency virus 1 | Activity | nan | None | 10.1016/j.bmc.2007.11.045 |
| Poliovirus 1 | Poliovirus 1 | Activity | nan | None | 10.1016/j.bmc.2007.11.045 |
| Rattus norvegicus | Rattus norvegicus | Inhibition | 47.4 | % | 10.1021/jm0580149 |
| Reovirus sp. | Reovirus sp. | Activity | nan | None | 10.1016/j.bmc.2007.11.045 |
| Respiratory syncytial virus | Respiratory syncytial virus | EC50 | 100000.0 | nM | 10.1016/j.bmc.2007.11.045 |
| Vaccinia virus | Vaccinia virus | Activity | nan | None | 10.1016/j.bmc.2007.11.045 |
| Vesicular stomatitis virus | Vesicular stomatitis virus | Activity | nan | None | 10.1016/j.bmc.2007.11.045 |
| Yellow fever virus | Yellow fever virus | EC50 | 100000.0 | nM | 10.1016/j.bmc.2007.11.045 |
| None | Molecular identity unknown | Lipid peroxidation | 7.6 | % | 10.1021/jm0580149 |
| None | Molecular identity unknown | Lipid peroxidation | nan | None | 10.1021/jm0580149 |
| None | Molecular identity unknown | Scavenging Activity | nan | None | 10.1021/jm0580149 |