UNIFLORINE B
AlkaPlorer ID: AK398879
Synonym: None
IUPAC Name: (1S,2R,5R,7R,8S,8aS)-1,2,3,5,6,7,8,8a-octahydroindolizine-1,2,5,7,8-pentol
Structure
SMILES: O[C@H]1[C@H]2[C@H](O)[C@H](O)CN2[C@H](O)C[C@H]1O
InChI: InChI=1S/C8H15NO5/c10-3-1-5(12)9-2-4(11)8(14)6(9)7(3)13/h3-8,10-14H,1-2H2/t3-,4-,5-,6+,7-,8-/m1/s1
InChIKey: HHLGVTQXFOVXKK-CVBHLRHXSA-N
Reference
a-glucosidase Inhibitors From Paraguayan Natural Medicine, Ñangapiry, The Leaves Of Eugenia Uniflora
PubChem CID: 46879415
LOTUS: LTS0020046
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Eugenia uniflora | Eugenia | Myrtaceae | Myrtales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 205.21
TPSA？: 104.39
MolLogP？: -3.1637
Number of H-Donors: 5
Number of H-Acceptors: 6
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Rattus norvegicus | Acidic alpha-glucosidase | IC50 | 4000.0 | nM | 10.1021/np900435d |
| Rattus norvegicus | Sucrase-isomaltase | IC50 | 1800.0 | nM | 10.1021/np900435d |