(3R)-3-hydroxy-2,2,10-trimethyl-3H,4H-pyrano[2,3-b]quinolin-5-one
AlkaPlorer ID: AK404757
Synonym: None
IUPAC Name: 3-hydroxy-2,2,10-trimethyl-3,4-dihydropyrano[2,3-b]quinolin-5-one
Structure
SMILES: CN1C2=C(CC(O)C(C)(C)O2)C(=O)C2=CC=CC=C21
InChI: InChI=1S/C15H17NO3/c1-15(2)12(17)8-10-13(18)9-6-4-5-7-11(9)16(3)14(10)19-15/h4-7,12,17H,8H2,1-3H3
InChIKey: HUPKGVIVTBASQC-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Teclea simplicifolia | Teclea | Rutaceae | Sapindales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 259.305
TPSA？: 51.46
MolLogP？: 1.6129000000000002
Number of H-Donors: 1
Number of H-Acceptors: 4
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Mus musculus | N1E-115 | BK | 0.0 | % | 10.1021/jm001007u |
| Mus musculus | N1E-115 | BNa | 0.0 | % | 10.1021/jm001007u |
| Mus musculus | Voltage-gated potassium channel subunit Kv1.3 | BK | nan | None | 10.1021/jm001007u |