4-(2-amino-2-carboxyethyl)-5-methyl-1,2-oxazole-3-carboxylic acid
AlkaPlorer ID: AK419654
Synonym: None
IUPAC Name: 4-[(2S)-2-amino-2-carboxyethyl]-5-methyl-1,2-oxazole-3-carboxylic acid
Structure
SMILES: CC1=C(C[C@H](N)C(=O)O)C(C(=O)O)=NO1
InChI: InChI=1S/C8H10N2O5/c1-3-4(2-5(9)7(11)12)6(8(13)14)10-15-3/h5H,2,9H2,1H3,(H,11,12)(H,13,14)/t5-/m0/s1
InChIKey: JDNMYUBSFDGCSX-YFKPBYRVSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Apis cerana | Apis | Apidae | Hymenoptera | Insecta | Arthropoda | Metazoa | Eukaryota |
Properties Information
Molecule Weight: 214.177
TPSA？: 126.65000000000002
MolLogP？: -0.36438
Number of H-Donors: 3
Number of H-Acceptors: 5
RingCount: 1
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Cystine/glutamate transporter | Activity | 98.0 | % | 10.1016/j.bmc.2009.11.001 |
| Homo sapiens | Glutamate receptor ionotropic, AMPA 1 | EC50 | 270.0 | nM | 10.1016/j.bmc.2009.12.072 |
| Homo sapiens | Glutamate receptor ionotropic, AMPA 3 | EC50 | 1600.0 | nM | 10.1016/j.bmc.2009.12.072 |
| None | Unchecked | EC50 | 1700.0 | nM | 10.1016/j.bmc.2009.12.072 |