Navigation

name Structure Reference Source Properties Activities Metabolism

Canertinib

AlkaPlorer ID: AK479894

Synonym: None

IUPAC Name: N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide

Structure

SMILES: C=CC(=O)NC1=C(OCCCN2CCOCC2)C=C2N=CN=C(NC3=CC=C(F)C(Cl)=C3)C2=C1

copy

InChI: InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)

copy

InChIKey: OMZCMEYTWSXEPZ-UHFFFAOYSA-N

copy

Source

Species Genus Family Order Class Phylum Kingdom Domain

Properties Information

Molecule Weight: 485.94700000000006

TPSA？: 88.61

MolLogP？: 4.391500000000003

Number of H-Donors: 2

Number of H-Acceptors: 7

RingCount: 4

Activities Information

Organism Target Name Standard Type Standard Value Standard Units doi
Canis lupus familiaris Liver microsome CLH 26.0 uL/min 10.1021/jm5014659
Chlorocebus sabaeus Vero CC50 10000.0 nM 10.1021/acs.jmedchem.0c01467
Gallus gallus Myosin light chain kinase, smooth muscle Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens 26S protease regulatory subunit 6B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens 3-phosphoinositide dependent protein kinase-1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens A-431 IC50 0.083 ug.mL-1 10.1016/s0960-894x(02)00598-x
Homo sapiens A-431 IC50 150.0 nM 10.1021/jm201591k
Homo sapiens A-431 Last therapy day 0.0 % 10.1021/jm990482t
Homo sapiens A-431 Last therapy day 4.0 % 10.1021/jm990482t
Homo sapiens A-431 T-C 41.3 day 10.1021/jm990482t
Homo sapiens A-431 T-C 53.2 day 10.1021/jm990482t
Homo sapiens A-431 Weight change -1.0 g 10.1021/jm990482t
Homo sapiens A-431 Weight change -0.4 g 10.1021/jm990482t
Homo sapiens A549 IC50 1590.0 nM 10.1021/jm201591k
Homo sapiens A549 IC50 7162.0 nM 10.1016/j.ejmech.2021.113328
Homo sapiens Actin-related protein 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Actin-related protein 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Activin receptor type-1 Kd 1700.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-1 Kd 1700.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Activin receptor type-1B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-1B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-1B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Activin receptor type-2A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-2A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-2B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Activin receptor type-2B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Activin receptor type-2B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Acyl-CoA dehydrogenase family member 10 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Acyl-CoA dehydrogenase family member 11 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Adaptor-associated kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Adaptor-associated kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Adaptor-associated kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Adaptor-associated kinase Kd nan None 10.1038/nbt1068
Homo sapiens Adenine phosphoribosyltransferase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Adenosine kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Adenylate kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ADP/ATP translocase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ADP/ATP translocase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ALK tyrosine kinase receptor Kd 7700.0 nM 10.1038/nbt.1990
Homo sapiens ALK tyrosine kinase receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens ALK tyrosine kinase receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens AMP-activated protein kinase, alpha-1 subunit Kd nan None 10.1038/nbt1068
Homo sapiens AMP-activated protein kinase, alpha-2 subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens AMP-activated protein kinase, alpha-2 subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens AMP-activated protein kinase, gamma-1 subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens AMP-activated protein kinase, gamma-2 subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ankyrin repeat and protein kinase domain-containing protein 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ankyrin repeat and protein kinase domain-containing protein 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens ATP-dependent RNA helicase DDX1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ATP-dependent RNA helicase DDX3X Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ATP-dependent RNA helicase DDX42 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens ATP-dependent RNA helicase DHX30 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens BJ IC50 5612.0 nM 10.1016/j.ejmech.2021.113328
Homo sapiens BMP-2-inducible protein kinase Kd 1600.0 nM 10.1038/nbt1068
Homo sapiens BMP-2-inducible protein kinase Kd 3800.0 nM 10.1038/nbt1358
Homo sapiens BMP-2-inducible protein kinase Kd 3800.0 nM 10.1038/nbt.1990
Homo sapiens BMP-2-inducible protein kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Bone morphogenetic protein receptor type-1A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Bone morphogenetic protein receptor type-1A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Bone morphogenetic protein receptor type-1A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Bone morphogenetic protein receptor type-1B Kd 2600.0 nM 10.1038/nbt.1990
Homo sapiens Bone morphogenetic protein receptor type-1B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Bone morphogenetic protein receptor type-2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Bone morphogenetic protein receptor type-2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Bone morphogenetic protein receptor type-2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Brain glycogen phosphorylase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Breakpoint cluster region protein Kd 687.0 nM 10.1126/science.aan4368
Homo sapiens BR serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens BR serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens BR serine/threonine-protein kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens BR serine/threonine-protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens BT-474 EC50 10.0 nM 10.1016/j.bmcl.2008.11.023
Homo sapiens Caco-2 Cell permeation nan None 10.1021/jm990482t
Homo sapiens Caco-2 Efflux nan None 10.1021/jm990482t
Homo sapiens Caco-2 Permeability 49.3 *10e6 10.1021/jm990482t
Homo sapiens Caco-2 Permeability 59.1 *10e6 10.1021/jm990482t
Homo sapiens CaM kinase I alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase I alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase I alpha Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase I delta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase I delta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase I delta Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase I gamma Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase I gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase I gamma Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase II alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II alpha Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase II beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II beta Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase II delta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II delta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II delta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens CaM kinase II delta Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase II gamma Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase II gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase II gamma Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens CaM kinase II gamma Kd nan None 10.1038/nbt1068
Homo sapiens CaM kinase IV Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM kinase IV Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM kinase IV Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens CaM-kinase kinase alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM-kinase kinase alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM-kinase kinase alpha Kd nan None 10.1038/nbt1068
Homo sapiens CaM-kinase kinase beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens CaM-kinase kinase beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens CaM-kinase kinase beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens CaM-kinase kinase beta Kd nan None 10.1038/nbt1068
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens cAMP-dependent protein kinase alpha-catalytic subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cAMP-dependent protein kinase beta-1 catalytic subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens cAMP-dependent protein kinase beta-1 catalytic subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens cAMP-dependent protein kinase beta-1 catalytic subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cAMP-dependent protein kinase, gamma catalytic subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cAMP-dependent protein kinase type II-alpha regulatory subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I delta Kd 4600.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I delta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I delta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I epsilon Kd 420.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I epsilon Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I epsilon Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I epsilon Kd nan None 10.1038/nbt1068
Homo sapiens Casein kinase I gamma 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I gamma 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I gamma 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I gamma 1 Kd nan None 10.1038/nbt1068
Homo sapiens Casein kinase I gamma 2 Kd 1862.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I gamma 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I gamma 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I gamma 2 Kd nan None 10.1038/nbt1068
Homo sapiens Casein kinase II alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase II alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase II alpha (prime) Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase II alpha (prime) Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase II alpha (prime) Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Casein kinase I isoform alpha-like Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I isoform alpha-like Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I isoform gamma-3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Casein kinase I isoform gamma-3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Casein kinase I isoform gamma-3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cell division cycle 2-like protein kinase 6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cell division cycle 2-like protein kinase 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cell division protein kinase 8 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cell division protein kinase 8 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens cGMP-dependent protein kinase 1 beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens cGMP-dependent protein kinase 1 beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens cGMP-dependent protein kinase 1 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens cGMP-dependent protein kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens cGMP-dependent protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Chaperone activity of bc1 complex-like, mitochondrial Kd 1500.0 nM 10.1038/nbt1358
Homo sapiens Chaperone activity of bc1 complex-like, mitochondrial Kd 1500.0 nM 10.1038/nbt.1990
Homo sapiens Chaperone activity of bc1 complex-like, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Chromodomain-helicase-DNA-binding protein 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Citron Rho-interacting kinase Kd 1300.0 nM 10.1038/nbt1358
Homo sapiens Citron Rho-interacting kinase Kd 1300.0 nM 10.1038/nbt.1990
Homo sapiens Citron Rho-interacting kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens c-Jun N-terminal kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens c-Jun N-terminal kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens c-Jun N-terminal kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens c-Jun N-terminal kinase 1 Kd nan None 10.1038/nbt1068
Homo sapiens c-Jun N-terminal kinase 2 Kd 1100.0 nM 10.1038/nbt1068
Homo sapiens c-Jun N-terminal kinase 2 Kd 1100.0 nM 10.1038/nbt.1990
Homo sapiens c-Jun N-terminal kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens c-Jun N-terminal kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens c-Jun N-terminal kinase 3 Kd 2800.0 nM 10.1038/nbt1068
Homo sapiens c-Jun N-terminal kinase 3 Kd 5500.0 nM 10.1038/nbt1358
Homo sapiens c-Jun N-terminal kinase 3 Kd 5500.0 nM 10.1038/nbt.1990
Homo sapiens c-Jun N-terminal kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 10 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 12 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 13 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 13 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 2 Kd nan None 10.1038/nbt1068
Homo sapiens Cyclin-dependent kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 5 Kd nan None 10.1038/nbt1068
Homo sapiens Cyclin-dependent kinase 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 7 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase 9 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Cyclin-dependent kinase 9 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase 9 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cyclin-dependent kinase-like 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase-like 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase-like 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cyclin-dependent kinase-like 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Cysteine--tRNA ligase, cytoplasmic Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Cytochrome c1, heme protein, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens dCTP pyrophosphatase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Death-associated protein kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Death-associated protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Death-associated protein kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Death-associated protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Death-associated protein kinase 2 Kd nan None 10.1038/nbt1068
Homo sapiens Death-associated protein kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Death-associated protein kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Death-associated protein kinase 3 Kd nan None 10.1038/nbt1068
Homo sapiens Delta(24)-sterol reductase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Deoxycytidine kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dipeptidyl peptidase I IC50 120.0 nM 10.1016/j.ejmech.2021.113818
Homo sapiens Dipeptidyl peptidase I IC50 2700.0 nM 10.1021/acs.jmedchem.9b00631
Homo sapiens Discoidin domain-containing receptor 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Discoidin domain-containing receptor 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Discoidin domain-containing receptor 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DnaJ homolog subfamily A member 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DNA replication licensing factor MCM4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens DNA topoisomerase II beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual serine/threonine and tyrosine protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Kd 1800.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Kd 1800.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Kd 1600.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Kd 1600.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 5 Kd 60.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity mitogen-activated protein kinase kinase 7 Kd 110.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase CLK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase CLK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase CLK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity protein kinase CLK2 Kd nan None 10.1038/nbt1068
Homo sapiens Dual specificity protein kinase CLK3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase CLK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase CLK3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity protein kinase CLK3 Kd nan None 10.1038/nbt1068
Homo sapiens Dual specificity protein kinase CLK4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase CLK4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase CLK4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity protein kinase CLK4 Kd nan None 10.1038/nbt1068
Homo sapiens Dual specificity protein kinase TTK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity protein kinase TTK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity protein kinase TTK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity protein kinase TTK Kd nan None 10.1038/nbt1068
Homo sapiens Dual specificity testis-specific protein kinase 1 Kd 3200.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity testis-specific protein kinase 1 Kd 3200.0 nM 10.1038/nbt.1990
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A Kd 1500.0 nM 10.1038/nbt.1990
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 1A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual-specificity tyrosine-phosphorylation regulated kinase 2 Kd 6700.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificty protein kinase CLK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Dual specificty protein kinase CLK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Dual specificty protein kinase CLK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Dual specificty protein kinase CLK1 Kd nan None 10.1038/nbt1068
Homo sapiens Dynamin-like 120 kDa protein, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Electron transfer flavoprotein subunit beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Elongation factor Tu, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 1 Kd 2500.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 1 Kd 2500.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 2 Kd nan None 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 3 Kd 650.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 3 Kd 2100.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 3 Kd 2100.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 4 Kd 310.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 4 Kd 3600.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 4 Kd 3600.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 5 Kd 270.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 5 Kd 1200.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 5 Kd 1200.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 5 Kd 1741.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 6 Kd 72.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 6 Kd 270.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 6 Kd 270.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 7 Kd 1190.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-A receptor 7 Kd 1500.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-A receptor 8 Kd 790.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-A receptor 8 Kd 2000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-A receptor 8 Kd 2000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 1 Kd 1400.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-B receptor 1 Kd 1500.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 2 Kd 2700.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 2 Kd 2700.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-B receptor 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-B receptor 4 Kd 1800.0 nM 10.1038/nbt1358
Homo sapiens Ephrin type-B receptor 4 Kd 1800.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 4 Kd 2083.0 nM 10.1126/science.aan4368
Homo sapiens Ephrin type-B receptor 4 Kd 5000.0 nM 10.1038/nbt1068
Homo sapiens Ephrin type-B receptor 6 Kd 640.0 nM 10.1038/nbt.1990
Homo sapiens Ephrin type-B receptor 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Epidermal growth factor receptor erbB1 IC50 0.1 nM 10.1016/j.bmc.2018.02.022
Homo sapiens Epidermal growth factor receptor erbB1 IC50 0.3 nM 10.1016/j.ejmech.2017.07.023
Homo sapiens Epidermal growth factor receptor erbB1 IC50 0.4 nM 10.1016/j.ejmech.2017.07.023
Homo sapiens Epidermal growth factor receptor erbB1 IC50 0.8 nM 10.1016/j.ejmech.2015.07.030
Homo sapiens Epidermal growth factor receptor erbB1 IC50 0.8 nM 10.1016/j.ejmech.2019.03.004
Homo sapiens Epidermal growth factor receptor erbB1 IC50 0.8 nM 10.1016/j.ejmech.2020.113016
Homo sapiens Epidermal growth factor receptor erbB1 IC50 0.8 nM 10.1021/acs.jmedchem.0c01467
Homo sapiens Epidermal growth factor receptor erbB1 IC50 1.26 nM 10.1016/j.bmc.2018.02.022
Homo sapiens Epidermal growth factor receptor erbB1 IC50 1.5 nM 10.1021/acs.jmedchem.0c01467
Homo sapiens Epidermal growth factor receptor erbB1 IC50 1.5 nM 10.1021/acs.jmedchem.1c01714
Homo sapiens Epidermal growth factor receptor erbB1 IC50 1.5 nM 10.1021/jm3003203
Homo sapiens Epidermal growth factor receptor erbB1 IC50 1.5 nM 10.1021/jm990482t
Homo sapiens Epidermal growth factor receptor erbB1 IC50 2.0 nM 10.1016/j.ejmech.2019.03.004
Homo sapiens Epidermal growth factor receptor erbB1 IC50 2.3 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Epidermal growth factor receptor erbB1 IC50 2.7 nM 10.1016/j.bmcl.2019.04.029
Homo sapiens Epidermal growth factor receptor erbB1 IC50 3.0 nM 10.1021/acs.jmedchem.5b01633
Homo sapiens Epidermal growth factor receptor erbB1 IC50 5.0 nM 10.1016/j.bmcl.2008.11.023
Homo sapiens Epidermal growth factor receptor erbB1 IC50 6.0 nM 10.1021/acs.jmedchem.5b01633
Homo sapiens Epidermal growth factor receptor erbB1 IC50 7.4 nM 10.1016/j.ejmech.2018.05.006
Homo sapiens Epidermal growth factor receptor erbB1 IC50 7.4 nM 10.1021/jm990482t
Homo sapiens Epidermal growth factor receptor erbB1 IC50 15.0 nM 10.1016/j.bmc.2018.12.032
Homo sapiens Epidermal growth factor receptor erbB1 IC50 26.0 nM 10.1016/j.ejmech.2017.07.023
Homo sapiens Epidermal growth factor receptor erbB1 IC50 74.0 nM 10.1016/s0960-894x(02)00598-x
Homo sapiens Epidermal growth factor receptor erbB1 Inhibition 80.0 % 10.1021/jm990482t
Homo sapiens Epidermal growth factor receptor erbB1 Inhibition nan % 10.1016/j.bmc.2018.02.022
Homo sapiens Epidermal growth factor receptor erbB1 Inhibition nan % 10.1021/jm400822z
Homo sapiens Epidermal growth factor receptor erbB1 Inhibition nan % 10.1021/ml4002437
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.1 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.13 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.13 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.17 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.17 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.19 nM 10.1021/acs.jmedchem.9b00350
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.19 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.19 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.22 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.22 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.24 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.24 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.26 nM 10.1038/nbt1358
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.26 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 0.28 nM 10.1038/nbt.1990
Homo sapiens Epidermal growth factor receptor erbB1 Kd 1.4 nM 10.1038/nbt1068
Homo sapiens Epidermal growth factor receptor erbB1 Kd 8.0 nM 10.1126/science.aan4368
Homo sapiens Epidermal growth factor receptor erbB1 Ki 0.11 nM 10.1021/acs.jmedchem.5b01633
Homo sapiens Epidermal growth factor receptor erbB1 Ratio 148000.0 /M/s 10.1021/acs.jmedchem.5b01633
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 400.0 nM 10.1038/nbt1358
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 400.0 nM 10.1038/nbt.1990
Homo sapiens Epithelial discoidin domain-containing receptor 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Eukaryotic peptide chain release factor GTP-binding subunit ERF3B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Eukaryotic translation initiation factor 5B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Exosome RNA helicase MTR4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ferrochelatase, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Fibroblast growth factor receptor 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Fibroblast growth factor receptor 1 Kd nan None 10.1038/nbt1068
Homo sapiens Fibroblast growth factor receptor 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 2 Kd nan None 10.1038/nbt1068
Homo sapiens Fibroblast growth factor receptor 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Fibroblast growth factor receptor 3 Kd nan None 10.1038/nbt1068
Homo sapiens Fibroblast growth factor receptor 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Fibroblast growth factor receptor 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Focal adhesion kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Focal adhesion kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Focal adhesion kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Focal adhesion kinase 1 Kd nan None 10.1038/nbt1068
Homo sapiens General transcription and DNA repair factor IIH helicase subunit XPD Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Glycine--tRNA ligase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Glycogen synthase kinase-3 alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Glycogen synthase kinase-3 alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Glycogen synthase kinase-3 alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Glycogen synthase kinase-3 beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Glycogen synthase kinase-3 beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Glycogen synthase kinase-3 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens G-protein coupled receptor kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens G protein-coupled receptor kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens G protein-coupled receptor kinase 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens GTP-binding nuclear protein Ran Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Guanine nucleotide-binding protein G(i) subunit alpha-2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens HCC827 IC50 0.3776 nM 10.1016/j.ejmech.2021.113328
Homo sapiens HEK-293T IC50 6000.0 nM 10.1016/j.ejmech.2021.113328
Homo sapiens Heme oxygenase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Hepatocyte growth factor receptor Kd 830.0 nM 10.1038/nbt.1990
Homo sapiens Hepatocyte growth factor receptor Kd 1700.0 nM 10.1038/nbt.1990
Homo sapiens Hepatocyte growth factor receptor Kd 5600.0 nM 10.1038/nbt1358
Homo sapiens Hepatocyte growth factor receptor Kd 5600.0 nM 10.1038/nbt.1990
Homo sapiens Hepatocyte growth factor receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens HepG2 IC50 relative 50000.0 nM 10.6019/EOS300108
Homo sapiens Histone deacetylase 6 Inhibition -6.72 % 10.6019/CHEMBL4808148
Homo sapiens Histone deacetylase 6 Inhibition 9.13 % 10.6019/CHEMBL4808148
Homo sapiens HN5 EC50 50.0 nM 10.1016/j.bmcl.2008.11.023
Homo sapiens Homeodomain-interacting protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Homeodomain-interacting protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Homeodomain-interacting protein kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Homeodomain-interacting protein kinase 4 Kd 1100.0 nM 10.1038/nbt.1990
Homo sapiens Hormonally up-regulated neu tumor-associated kinase Kd 6400.0 nM 10.1038/nbt.1990
Homo sapiens Inhibitor of nuclear factor kappa B kinase alpha subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Inhibitor of nuclear factor kappa B kinase beta subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Inhibitor of nuclear factor kappa B kinase epsilon subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Inosine-5'-monophosphate dehydrogenase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Insulin-like growth factor I receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Insulin-like growth factor I receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Insulin-like growth factor I receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Insulin receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Insulin receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Insulin receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Insulin receptor Kd nan None 10.1038/nbt1068
Homo sapiens Insulin receptor-related protein Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Insulin receptor-related protein Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Interferon-induced, double-stranded RNA-activated protein kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Interferon-induced, double-stranded RNA-activated protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Interleukin-1 receptor-associated kinase 1 Kd 450.0 nM 10.1038/nbt.1990
Homo sapiens Interleukin-1 receptor-associated kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Interleukin-1 receptor-associated kinase 3 Kd 3000.0 nM 10.1038/nbt1358
Homo sapiens Interleukin-1 receptor-associated kinase 3 Kd 3000.0 nM 10.1038/nbt.1990
Homo sapiens Interleukin-1 receptor-associated kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Interleukin-1 receptor-associated kinase 4 Kd 1200.0 nM 10.1038/nbt.1990
Homo sapiens Interleukin-1 receptor-associated kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Isoleucine--tRNA ligase, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Leucine-rich repeat serine/threonine-protein kinase 2 Kd 500.0 nM 10.1038/nbt.1990
Homo sapiens Leucine-rich repeat serine/threonine-protein kinase 2 Kd 1100.0 nM 10.1038/nbt.1990
Homo sapiens Leukocyte tyrosine kinase receptor Kd 5100.0 nM 10.1038/nbt.1990
Homo sapiens Leukocyte tyrosine kinase receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens LIM domain kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens LIM domain kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens LIM domain kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens LIM domain kinase 1 Kd nan None 10.1038/nbt1068
Homo sapiens LIM domain kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens LIM domain kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens LIM domain kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Liver glycogen phosphorylase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Liver microsome CLH 50.0 uL/min 10.1021/jm5014659
Homo sapiens Long-chain-fatty-acid--CoA ligase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Macrophage colony stimulating factor receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Macrophage colony stimulating factor receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Macrophage colony stimulating factor receptor Selectivity 0.0 None 10.1038/nbt1358
Homo sapiens Macrophage-stimulating protein receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Macrophage-stimulating protein receptor Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase-activated protein kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase-activated protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase-activated protein kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase-activated protein kinase 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase-activated protein kinase 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase-activated protein kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase ERK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase ERK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase ERK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase ERK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase ERK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase ERK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase-interacting serine/threonine-protein kinase MNK1 Kd 260.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase-interacting serine/threonine-protein kinase MNK1 Kd 260.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase p38 alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase p38 alpha Kd nan None 10.1038/nbt1068
Homo sapiens MAP kinase p38 beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase p38 beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP kinase p38 beta Kd nan None 10.1038/nbt1068
Homo sapiens MAP kinase p38 delta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 gamma Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase p38 gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP kinase p38 gamma Kd nan None 10.1038/nbt1068
Homo sapiens MAP kinase signal-integrating kinase 2 Kd 1300.0 nM 10.1038/nbt1068
Homo sapiens MAP kinase signal-integrating kinase 2 Kd 1800.0 nM 10.1038/nbt1358
Homo sapiens MAP kinase signal-integrating kinase 2 Kd 1800.0 nM 10.1038/nbt.1990
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens MAP/microtubule affinity-regulating kinase 2 Kd nan None 10.1038/nbt1068
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens MAP/microtubule affinity-regulating kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Maternal embryonic leucine zipper kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Maternal embryonic leucine zipper kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Maternal embryonic leucine zipper kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Membrane-associated progesterone receptor component 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Microtubule-associated serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Midasin Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Misshapen-like kinase 1 Kd 2100.0 nM 10.1038/nbt.1990
Homo sapiens Misshapen-like kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase 15 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 15 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 15 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase 4 Kd 5400.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 6 Kd 1700.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 6 Kd 1700.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase 7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase 7 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 10 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 10 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 11 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 12 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 13 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 15 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 2 Kd 3800.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 3 Kd 2300.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 2000.0 nM 10.1038/nbt1068
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 8400.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 8400.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 5 Kd nan None 10.1038/nbt1068
Homo sapiens Mitogen-activated protein kinase kinase kinase 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase 7 Kd 3300.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase 9 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase 9 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 2 Kd 330.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 1300.0 nM 10.1038/nbt1068
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 2600.0 nM 10.1038/nbt1358
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 2600.0 nM 10.1038/nbt.1990
Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mitotic checkpoint serine/threonine-protein kinase BUB1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Mixed lineage kinase 7 Kd 1200.0 nM 10.1038/nbt1358
Homo sapiens Mixed lineage kinase 7 Kd 1200.0 nM 10.1038/nbt.1990
Homo sapiens Mixed lineage kinase 7 Kd 2819.0 nM 10.1126/science.aan4368
Homo sapiens Multifunctional protein ADE2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Muscle, skeletal receptor tyrosine protein kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Muscle, skeletal receptor tyrosine protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin-10 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Myosin-14 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Myosin IIIA Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Myosin IIIA Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin-IIIB Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Myosin-IIIB Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin light chain kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin light chain kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens myosin light chain kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens myosin light chain kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens myosin light chain kinase 2 Kd nan None 10.1038/nbt1068
Homo sapiens Myosin light chain kinase family member 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Myosin light chain kinase family member 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin light chain kinase, smooth muscle Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Myosin light chain kinase, smooth muscle Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Myosin light chain kinase, smooth muscle Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Myotonin-protein kinase Kd 7000.0 nM 10.1038/nbt.1990
Homo sapiens Myotonin-protein kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens NCI-H1975 IC50 11.34 nM 10.1016/j.ejmech.2021.113328
Homo sapiens NCI-H1975 IC50 64.0 nM 10.1021/jm201591k
Homo sapiens NCI-H1975 IC50 101.0 nM 10.1016/j.ejmech.2017.07.023
Homo sapiens NCI-H1975 Inhibition nan % 10.1016/j.ejmech.2021.113328
Homo sapiens Nerve growth factor receptor Trk-A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Nerve growth factor receptor Trk-A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Nerve growth factor receptor Trk-A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Nerve growth factor receptor Trk-A Kd nan None 10.1038/nbt1068
Homo sapiens Neurotrophic tyrosine kinase receptor type 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Neurotrophic tyrosine kinase receptor type 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Non-receptor tyrosine-protein kinase TNK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Non-receptor tyrosine-protein kinase TNK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Non-receptor tyrosine-protein kinase TNK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens NT-3 growth factor receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens NT-3 growth factor receptor Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens NUAK family SNF1-like kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens NUAK family SNF1-like kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens NUAK family SNF1-like kinase 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens NUAK family SNF1-like kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens NUAK family SNF1-like kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Nucleolar GTP-binding protein 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Obg-like ATPase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens PC-9 IC50 0.8585 nM 10.1016/j.ejmech.2021.113328
Homo sapiens Peripheral plasma membrane protein CASK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Peroxisomal acyl-coenzyme A oxidase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Peroxisomal acyl-coenzyme A oxidase 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phenylalanine--tRNA ligase beta subunit Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphatidylethanolamine-binding protein 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphofructokinase platelet type Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphorylase kinase gamma subunit 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Phosphorylase kinase gamma subunit 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphorylase kinase gamma subunit 1 Kd nan None 10.1038/nbt1068
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Phosphorylase kinase gamma subunit 2 Kd nan None 10.1038/nbt1068
Homo sapiens PI3-kinase p110-alpha subunit Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens PI3-kinase p110-alpha subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-beta subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-delta subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI3-kinase p110-gamma subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PI4-kinase beta subunit Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens PITSLRE serine/threonine-protein kinase CDC2L2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Platelet-derived growth factor receptor alpha Kd 5200.0 nM 10.1038/nbt1358
Homo sapiens Platelet-derived growth factor receptor alpha Kd 5200.0 nM 10.1038/nbt.1990
Homo sapiens Platelet-derived growth factor receptor beta Kd 7500.0 nM 10.1038/nbt1358
Homo sapiens Platelet-derived growth factor receptor beta Kd 7500.0 nM 10.1038/nbt.1990
Homo sapiens Platelet-derived growth factor receptor beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Platelet-derived growth factor receptor beta Kd nan None 10.1038/nbt1068
Homo sapiens Probable ATP-dependent RNA helicase DDX6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein cereblon/Epidermal growth factor receptor Activity 15.0 % 10.1016/j.ejmech.2021.113328
Homo sapiens Protein cereblon/Epidermal growth factor receptor DC50 nan None 10.1016/j.ejmech.2021.113328
Homo sapiens Protein kinase C alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C alpha Kd nan None 10.1038/nbt1068
Homo sapiens Protein kinase C beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C delta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C delta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C delta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C epsilon Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C epsilon Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C eta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C eta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C iota Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C iota Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C mu Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C mu Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C nu Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C nu Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C nu Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C theta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase C theta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase C theta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase C zeta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase N1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase N1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase N1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein kinase N2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein kinase N2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein kinase N2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Protein tyrosine kinase 2 beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Protein tyrosine kinase 2 beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Protein tyrosine kinase 2 beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Proto-oncogene tyrosine-protein kinase MER Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Proto-oncogene tyrosine-protein kinase MER Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Proto-oncogene tyrosine-protein kinase ROS Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Proto-oncogene tyrosine-protein kinase ROS Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Putative heat shock protein HSP 90-beta 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Putative uncharacterized serine/threonine-protein kinase SgK110 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Pyridoxal kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Quinone reductase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Rab-like protein 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ras-related protein Rab-10 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ras-related protein Rab-27A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ras-related protein Rab-6A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Receptor-interacting serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Receptor-interacting serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Receptor-interacting serine/threonine-protein kinase 3 Kd 2254.0 nM 10.1126/science.aan4368
Homo sapiens Receptor-interacting serine/threonine-protein kinase 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 5.0 nM 10.1021/jm3003203
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 9.0 nM 10.1021/acs.jmedchem.0c01467
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 9.0 nM 10.1021/acs.jmedchem.1c01714
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 9.0 nM 10.1021/jm990482t
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 19.0 nM 10.1016/j.ejmech.2019.03.004
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 19.0 nM 10.1021/acs.jmedchem.0c01467
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 30.0 nM 10.1016/j.ejmech.2017.07.023
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 48.0 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 80.0 nM 10.1016/j.bmcl.2008.11.023
Homo sapiens Receptor protein-tyrosine kinase erbB-2 IC50 529.0 nM 10.1016/s0960-894x(02)00598-x
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Kd 8.4 nM 10.1038/nbt1068
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Kd 56.0 nM 10.1038/nbt.1990
Homo sapiens Receptor protein-tyrosine kinase erbB-2 Kd 87.0 nM 10.1038/nbt1358
Homo sapiens Receptor protein-tyrosine kinase erbB-4 IC50 7.0 nM 10.1021/acs.jmedchem.0c01467
Homo sapiens Receptor protein-tyrosine kinase erbB-4 IC50 10.0 nM 10.1021/jm3003203
Homo sapiens Receptor protein-tyrosine kinase erbB-4 IC50 14.0 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Receptor protein-tyrosine kinase erbB-4 Kd 6.5 nM 10.1038/nbt.1990
Homo sapiens Receptor tyrosine-protein kinase erbB-3 Kd 210.0 nM 10.1038/nbt.1990
Homo sapiens Rho-associated protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Rho-associated protein kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Rho-associated protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Rho-associated protein kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Rhodopsin kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 6200.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 6200.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 2 Kd nan None 10.1038/nbt1068
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 3 Kd nan None 10.1038/nbt1068
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Ribosomal protein S6 kinase alpha 5 Kd nan None 10.1038/nbt1068
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Ribosomal protein S6 kinase alpha 6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens RNA cytidine acetyltransferase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens S-adenosylmethionine synthase isoform type-2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Septin-9 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 10 Kd 430.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 10 Kd 1900.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 10 Kd 1900.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 10 Kd 5820.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 11 IC50 10000.0 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Serine/threonine-protein kinase 11 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 11 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 11 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 16 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 16 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 16 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 16 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 17A Kd 3800.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 17A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 17A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 17B Kd 7300.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 17B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 17B Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 2 Kd 440.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 2 Kd 1800.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 2 Kd 1800.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase 24 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 24 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 25 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 25 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 32A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 32B Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 32B Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 32C Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 32C Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 33 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 33 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 35 Kd 2900.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 36 Kd 2700.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase 36 Kd 4500.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 36 Kd 4500.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 38 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 38-like Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase 38-like Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase 38-like Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase AKT Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase AKT Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase AKT Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase AKT2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase AKT2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase AKT2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase AKT3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase AKT3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase AKT3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase A-Raf Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Aurora-A Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase Aurora-B Kd 4200.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Aurora-B Kd 4200.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Aurora-B Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Aurora-C Kd 2800.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Aurora-C Kd 2800.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Aurora-C Kd 3500.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase B-raf Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase B-raf Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase B-raf Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Chk1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Chk1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Chk1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Chk2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase c-TAK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase c-TAK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase c-TAK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase D2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase D2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase D2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase DCLK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase DCLK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase DCLK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase DCLK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase DCLK3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase DCLK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase GAK Kd 44.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase GAK Kd 100.0 nM 10.1021/acs.jmedchem.9b00350
Homo sapiens Serine/threonine-protein kinase GAK Kd 100.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase GAK Kd 100.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase GAK Kd 1351.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase ICK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ICK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase ILK-1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase LATS1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase LATS1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase LATS1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase LATS2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase LATS2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MAK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MARK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MARK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MRCK-A Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MRCK-A Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MRCK-A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MRCK beta Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MRCK beta Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MRCK beta Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MRCK gamma Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MRCK gamma Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MRCK gamma Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MST1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MST1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MST1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MST1 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase MST2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MST2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MST2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase MST4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase MST4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase MST4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase mTOR Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase mTOR Potency 11530.5 nM None
Homo sapiens Serine/threonine-protein kinase mTOR Potency 16287.3 nM None
Homo sapiens Serine/threonine-protein kinase Nek1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Nek1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Nek11 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase NEK2 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase Nek3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase Nek4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Nek5 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase Nek5 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK6 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase NEK7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK7 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase NEK9 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase NEK9 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase NEK9 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase NEK9 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase NIM1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine protein kinase NLK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine protein kinase NLK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine protein kinase NLK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase OSR1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 1 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PAK 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PAK 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 3 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PAK 4 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PAK6 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK6 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PAK6 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PAK7 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PAK7 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PAK7 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PCTAIRE-1 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PCTAIRE-2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PCTAIRE-2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PCTAIRE-2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PCTAIRE-3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PCTAIRE-3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PFTAIRE-1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PFTAIRE-1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PFTAIRE-2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PIM1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PIM1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PIM1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PIM1 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PIM2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PIM2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PIM2 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PIM3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PIM3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PLK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PLK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PLK4 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase PLK4 Kd nan None 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase PRKX Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase PRKX Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase PRP4 homolog Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RAF Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RAF Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase receptor R3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase receptor R3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIO1 Kd 8400.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIO1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RIO2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIO3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RIO3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 300.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 300.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 330.0 nM 10.1038/nbt1068
Homo sapiens Serine/threonine-protein kinase RIPK2 Kd 679.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase SBK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase Sgk3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SIK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SIK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SIK2 Kd 4900.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SIK2 Kd 4900.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SIK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase SIK3 Kd 700.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SIK3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase SRPK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SRPK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SRPK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase SRPK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase SRPK3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TAO1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TAO1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TAO2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TAO2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TAO3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TAO3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TBK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase TBK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase TNNI3K Kd 5600.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase TNNI3K Kd 5600.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase tousled-like 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase tousled-like 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase tousled-like 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase tousled-like 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ULK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ULK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase ULK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ULK3 Kd 4700.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase ULK3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Serine/threonine-protein kinase VRK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase WEE1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Serine/threonine-protein kinase WEE1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Serine/threonine-protein kinase WEE1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Signal recognition particle receptor subunit alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens SK-BR-3 IC50 0.102 ug.mL-1 10.1016/s0960-894x(02)00598-x
Homo sapiens SNF-related serine/threonine-protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens SPS1/STE20-related protein kinase YSK4 Kd 700.0 nM 10.1038/nbt.1990
Homo sapiens STE20-related kinase adapter protein alpha Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens STE20/SPS1-related proline-alanine-rich protein kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 600.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 700.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 1900.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 3900.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 3900.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 5700.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 7800.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 7800.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 7900.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd 7900.0 nM 10.1038/nbt.1990
Homo sapiens Stem cell growth factor receptor Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Stem cell growth factor receptor Kd nan None 10.1038/nbt1068
Homo sapiens Structural maintenance of chromosomes protein 1A Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Structural maintenance of chromosomes protein 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens SW-620 IC50 1.45 ug.mL-1 10.1016/s0960-894x(02)00598-x
Homo sapiens Testis-specific serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Testis-specific serine/threonine-protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens TGF-beta receptor type I Kd 9600.0 nM 10.1038/nbt1358
Homo sapiens TGF-beta receptor type I Kd 9600.0 nM 10.1038/nbt.1990
Homo sapiens TGF-beta receptor type I Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TGF-beta receptor type II Kd 800.0 nM 10.1038/nbt1358
Homo sapiens TGF-beta receptor type II Kd 800.0 nM 10.1038/nbt.1990
Homo sapiens Thyroid hormone receptor-associated protein 3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TP53-regulating kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TRAF2- and NCK-interacting kinase Kd 8200.0 nM 10.1038/nbt.1990
Homo sapiens TRAF2- and NCK-interacting kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens TRAF2- and NCK-interacting kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens TRAF2- and NCK-interacting kinase Kd nan None 10.1038/nbt1068
Homo sapiens Transient receptor potential cation channel subfamily M member 6 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine- and threonine-specific cdc2-inhibitory kinase Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine kinase non-receptor protein 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine kinase non-receptor protein 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine kinase non-receptor protein 2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine kinase non-receptor protein 2 Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 22.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 30.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 38.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 42.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 46.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 57.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 69.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 91.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 200.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 210.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 290.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 320.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 340.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 420.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 470.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 500.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 550.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 560.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 640.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 690.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 730.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 1000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 1000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 1400.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL Kd 1500.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 2900.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL Kd 3200.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase ABL2 Kd 870.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ABL2 Kd 870.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase ABL2 Kd 1300.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase ABL2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase BLK IC50 29.0 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Tyrosine-protein kinase BLK IC50 50.0 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Tyrosine-protein kinase BLK Kd 45.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BLK Kd 45.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase BMX Activity nan None 10.1016/j.bmcl.2008.07.062
Homo sapiens Tyrosine-protein kinase BMX IC50 62.0 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Tyrosine-protein kinase BMX IC50 586.0 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Tyrosine-protein kinase BMX Kd 1200.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase BMX Kd 2600.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BMX Kd 2600.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase BRK Kd 1100.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase BRK Kd 3800.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BRK Kd 3800.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase BRK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase BTK IC50 185.0 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Tyrosine-protein kinase BTK Kd 504.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase BTK Kd 750.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase BTK Kd 1600.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase BTK Kd 1600.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase CSK Kd 2900.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase CSK Kd 6100.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase CSK Kd 6100.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase CSK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase CTK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FER Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FER Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FER Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FER Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase FES Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FES Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FES Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FGR Kd 1700.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase FGR Kd 2800.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FGR Kd 2800.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FRK Kd 3400.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FRK Kd 3400.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FRK Kd 8100.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase FRK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FYN Kd 5300.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase FYN Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase FYN Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase FYN Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase HCK Kd 4200.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase HCK Kd 4200.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase HCK Kd 5700.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase HCK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase ITK/TSK IC50 5650.0 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Tyrosine-protein kinase ITK/TSK Kd 5600.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ITK/TSK Kd 5600.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase JAK1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase JAK1 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase JAK1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase JAK1 Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase JAK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase JAK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase JAK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase JAK2 Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase JAK3 IC50 2000.0 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Tyrosine-protein kinase JAK3 IC50 3880.0 nM 10.1016/j.bmcl.2008.07.062
Homo sapiens Tyrosine-protein kinase JAK3 Kd 630.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase JAK3 Kd 630.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase LCK Kd 320.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase LCK Kd 320.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase LCK Kd 560.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase LCK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase Lyn Kd 780.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase Lyn Kd 810.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase Lyn Kd 810.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase Lyn Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 490.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 730.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 730.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 1200.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 1200.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 1600.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 2400.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 2400.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 2700.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 2700.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 3000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 3000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase receptor FLT3 Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase receptor RET Kd 840.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor RET Kd 840.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor RET Kd 2485.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase receptor RET Kd 4200.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor RET Kd 4200.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor RET Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor Tie-1 Kd 2200.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor Tie-1 Kd 2200.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Kd 1000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor TYRO3 Kd 1000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase receptor UFO Kd 5700.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase receptor UFO Kd 5700.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase SRC Kd 760.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase SRC Kd 1100.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase SRC Kd 1100.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase SRC Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase Srms Kd 6700.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase Srms Kd 6700.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase SYK Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase SYK Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase SYK Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase SYK Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase TEC Kd 1500.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TEC Kd 1500.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TEC Kd 2132.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase TIE-2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TIE-2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TIE-2 Kd nan None 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase TXK Kd 700.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TXK Kd 700.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TYK2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase TYK2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase TYK2 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase YES Kd 1600.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase YES Kd 1600.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosine-protein kinase YES Kd 2500.0 nM 10.1038/nbt1068
Homo sapiens Tyrosine-protein kinase YES Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Tyrosine-protein kinase YES Potency 172.9 nM None
Homo sapiens Tyrosine-protein kinase ZAP-70 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Tyrosine-protein kinase ZAP-70 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 4731.8 nM None
Homo sapiens Tyrosyl-DNA phosphodiesterase 1 Potency 5309.1 nM None
Homo sapiens Tyrosyl-tRNA synthetase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens U5 small nuclear ribonucleoprotein 200 kDa helicase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens UMP-CMP kinase Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Uncharacterized aarF domain-containing protein kinase 1 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Uncharacterized aarF domain-containing protein kinase 4 Kd 3400.0 nM 10.1038/nbt1358
Homo sapiens Uncharacterized aarF domain-containing protein kinase 4 Kd 3400.0 nM 10.1038/nbt.1990
Homo sapiens Uncharacterized protein FLJ45252 Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Vascular endothelial growth factor receptor 1 Kd 7500.0 nM 10.1038/nbt.1990
Homo sapiens Vascular endothelial growth factor receptor 1 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Vascular endothelial growth factor receptor 2 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Vascular endothelial growth factor receptor 2 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Vascular endothelial growth factor receptor 2 Kd nan None 10.1038/nbt1068
Homo sapiens Vascular endothelial growth factor receptor 3 Kd 10000.0 nM 10.1038/nbt1358
Homo sapiens Vascular endothelial growth factor receptor 3 Kd 10000.0 nM 10.1038/nbt.1990
Homo sapiens Vascular endothelial growth factor receptor 3 Kd nan None 10.1038/nbt1068
Homo sapiens Very long-chain specific acyl-CoA dehydrogenase, mitochondrial Kd 30000.0 nM 10.1126/science.aan4368
Homo sapiens Wee1-like protein kinase 2 Kd 10000.0 nM 10.1038/nbt.1990
Mus musculus BaF3 IC50 9.2 nM 10.1016/j.ejmech.2021.113328
Mus musculus Liver CLH 5.0 uL/min 10.1021/jm5014659
Mus musculus Serine/threonine-protein kinase MST2 Kd nan None 10.1038/nbt1068
Mus musculus ULK3 kinase Kd nan None 10.1038/nbt1068
Mycobacterium tuberculosis Serine/threonine-protein kinase pknB Kd 10000.0 nM 10.1038/nbt.1990
Plasmodium falciparum Calcium-dependent protein kinase 1 Kd 10000.0 nM 10.1038/nbt.1990
Plasmodium falciparum (isolate 3D7) Cell division control protein 2 homolog Kd 10000.0 nM 10.1038/nbt.1990
Rattus norvegicus Liver microsome CLH 105.0 uL/min 10.1021/jm5014659
Rattus norvegicus Tubulin alpha-1 chain Kd 29.0 nM 10.1038/nbt1358
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition -67.61 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 Replicase polyprotein 1ab Inhibition 19.67 % 10.6019/CHEMBL4495564
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 19952.62 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 IC50 20000.0 nM 10.6019/CHEMBL4651402
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition -0.23 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 0.22 % 10.6019/CHEMBL4495565
Severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 Inhibition 3.21 % 10.21203/rs.3.rs-23951/v1
Variola virus Variola virus Activity 30.0 None 10.1021/acs.jmedchem.0c01467
None ADMET CLH 221.0 uL/min 10.1021/jm5014659
None ADMET IC50 2300.0 nM 10.1021/jm201591k
None ADMET permeability nan None 10.1021/acs.jmedchem.5b01633
None NON-PROTEIN TARGET IC50 1.0 nM 10.1021/jm201591k
None NON-PROTEIN TARGET Potency 10583.9 nM None
None NON-PROTEIN TARGET Potency 23485.0 nM None
None No relevant target Drug metabolism 100.0 % 10.1016/j.bmc.2016.04.046
None No relevant target LogD nan None 10.1021/acs.jmedchem.5b01633
None No relevant target Solubility 800.0 nM 10.6019/CHEMBL3301361
None No relevant target T1/2 0.35 hr 10.1021/acs.jmedchem.6b01894
None No relevant target T1/2 0.3833 hr 10.1021/jm400822z
None Unchecked Ac50 2.818 uM None
None Unchecked Ac50 3.162 uM None
None Unchecked Ac50 6.31 uM None
None Unchecked Ac50 13.67 uM None
None Unchecked Ac50 15.34 uM None
None Unchecked Ac50 24.32 uM None
None Unchecked AC50 2818.4 nM None
None Unchecked AC50 3162.3 nM None
None Unchecked AC50 6309.6 nM None
None Unchecked CC50 10000.0 nM 10.1021/acs.jmedchem.0c01467
None Unchecked IC50 0.04 nM 10.1016/j.bmc.2018.02.022
None Unchecked IC50 70.19 nM 10.1016/j.ejmech.2021.113328
None Unchecked IC50 80.0 nM 10.1021/acs.jmedchem.9b00350
None Unchecked IC50 1001.7 nM None
None Unchecked IC50 2093.6 nM None
None Unchecked IC50 4293.4 nM None
None Unchecked IC50 8872.9 nM None
None Unchecked IC50 9462.8 nM None
None Unchecked IC50 10000.0 nM None
None Unchecked IC50 17000.0 nM 10.1021/acs.jmedchem.9b00350
None Unchecked Inhibition nan % 10.1021/jm400822z
None Unchecked Kd 30000.0 nM 10.1126/science.aan4368
None Unchecked MOTILITY REDUCTION/CYTOTOXICITY 0.0 % 10.6019/CHEMBL3988181
None Unchecked Potency 5257.6 nM None
None Unchecked Potency 5899.2 nM None
None Unchecked Potency 7079.5 nM None
None Unchecked Potency 14818.0 nM None
None Unchecked Potency 16771.6 nM None
None Unchecked Potency 18654.8 nM None
None Unchecked Potency 26350.6 nM None
None Unchecked Potency 33173.4 nM None
None Unchecked Potency 35481.3 nM None
None Unchecked Potency 37221.2 nM None
None Unchecked Potency 74266.1 nM None
None Unchecked Ratio 1.0 None 10.1021/acs.jmedchem.5b01633

Metabolism Information