3-hydroxy-2,2-dimethyl-2H,3H,4H,5H,10H-pyrano[2,3-b]quinolin-5-one
AlkaPlorer ID: AK487723
Synonym: None
IUPAC Name: 3-hydroxy-2,2-dimethyl-4,10-dihydro-3H-pyrano[2,3-b]quinolin-5-one
Structure
SMILES: CC1(C)OC2=C(CC1O)C(=O)C1=CC=CC=C1N2
InChI: InChI=1S/C14H15NO3/c1-14(2)11(16)7-9-12(17)8-5-3-4-6-10(8)15-13(9)18-14/h3-6,11,16H,7H2,1-2H3,(H,15,17)
InChIKey: PFODDKQREAWOLH-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 245.278
TPSA？: 62.32
MolLogP？: 1.6024999999999996
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Mus musculus | N1E-115 | BK | 0.0 | % | 10.1021/jm001007u |
| Mus musculus | N1E-115 | BNa | 0.0 | % | 10.1021/jm001007u |
| Mus musculus | Voltage-gated potassium channel subunit Kv1.3 | BK | nan | None | 10.1021/jm001007u |